JP4543166B2 - Database and analysis service operation integration system, method and program thereof - Google Patents

Description

The present invention relates to an interface technology, and more particularly to an operation integration system for a database and an analysis service.

With the development of the Internet, various services have been provided through the WWW. Since services through the WWW can be used in a unified environment using a Web browser, technical barriers for users to use are low, and the convenience of being accessible anywhere, anytime is spreading. .
On the other hand, with the rapid development of biotechnology in recent years, resources such as biological databases and analysis services such as proteins and nucleic acids have been established, and these have been provided through the WWW.

For example, the following are provided as databases.
(1) NCBI Protein (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Protein): Protein database (NCBI: National Center for Biolotechnology Information (USA))
(2) NCBI Nucleotide (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Nucleotide): Nucleic acid database (3) NCBI UniGene (http: //www.ncbi.nlm.nih .gov / entrez / query.fcgi? db = unigene): Sequence database without protein duplication (4) NCBI OMIM (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM ): Gene database (disease related)
(5) Protein Data Bank (http://www.rcsb.org/pdb/): Protein 3D structure database

In addition, the following services are provided as analysis services.
(1) CBS TMHMM (http://www.cbs.dtu.dk/services/TMHMM/): prediction of transmembrane region of protein
CBS: center for biological sequence Analysis at the Technical University of Denmark
(2) CBS NetNGlyc 1.0 Server (http://www.cbs.dtu.dk/services/NetNGlyc/): N-type sugar chain binding site prediction (3) CBS NetOGlyc 3.0 Server Beta (http://www.cbs. dtu.dk/services/NetOGlyc/): O-glycan binding site prediction (4) CBS NetPhos 2.0 Server (http://www.cbs.dtu.dk/services/NetPhos/): phosphorylation site prediction (5) CBS TargetP Server v1.01 (http://www.cbs.dtu.dk/services/TargetP/): Prediction of protein location

The specific advantages and disadvantages of each service are described below.
・ Http://bioinfo.pl/Meta/(Polish Bioinformatics Site MetaServer)
For this service, enter an array and select a service to return the result. An advantage of this service is that a plurality of services can be selected. However, the disadvantage of this service is that there is no database part (that is, it is necessary to set data by yourself) and that only one array can be selected at a time.
・ Http://www.genome.ad.jp/dbget/dbget.links.html (genome net WWW server integrated database search system)
In this database, it is possible to access various databases and obtain information from keywords. The advantage of this service is that it covers many databases. A disadvantage of this service is the lack of a service section (function to analyze the array).
・ Http://srs.embl-heidelberg.de:8000/srs5/(Sequence Retrieval System)
The advantage of this service is that it covers many databases. A disadvantage of this service is the lack of a service section (function to analyze the array).

  As described above, there is no service that integrates the functions of the database and the analysis service, and it is necessary to learn how to use each when using them. In addition, in order to use the database search result to analyze with the analysis service, the search result must be manually input as an analysis condition. This imposes a heavy burden on the user.

  Resources that exist on the Internet as described above have different usage methods and interfaces, and it takes a lot of time to learn how to use multiple services. Each user must work not only on the contents of the service but also on which Web site the service is provided. Since services provided on different websites need to be operated according to different usage procedures for each service, more time is required for operation. When a plurality of resources are used, the work time gradually increases as the number of resources increases. In addition, in order to use other services using the results of each service, it is necessary to connect the output format of the service results to the input format of other services, which also takes a lot of time. . In addition, beginners in the field of biology need knowledge to find out what databases and analysis services are available.

  The present invention is a system for solving such a problem, and provides a system that provides a user with an environment for efficient work by making it possible to use biological resources on a network with a unified interface. With the goal.

The above problems are solved by the present invention having the following features. That is, the invention described in claim 1 includes an input unit for inputting information from a user and a display unit for displaying information to the user, and each provides one or more database servers and analysis services that respectively provide databases. A database functioning computer and analysis service operation integration system connected to one or more analysis service servers through the Internet, using an address for connecting to each of the database servers and each of the databases a database access information storage means for storing a database access information indicating the operation procedure information including information and data format of an interface for, the database represented on the display unit has an input field for inputting a search condition And, a database symbol storage means for storing a database symbol, for accepting an operation on the database, the address for connection to the respective analysis service server, and information of an interface for using each of the analysis service and Analysis service access information storage means for storing analysis service access information representing operation procedure information including a data format, and an integrated resource in which a plurality of databases and resources of the analysis service are associated in a predetermined access order and operation order Resource integrated information storage means for storing resource integrated information, and an analysis service for displaying the analysis service on the display means and storing an analysis service symbol for accepting an operation on the analysis service Symbol storage means, resource integrated symbol storage means for displaying the integrated resource on the display means, and storing a resource integration symbol for accepting an operation on the integrated resource, the database symbol, and the analysis service symbol And symbol display means for displaying the resource integration symbol on the display means, input operation for the database, the analysis service, or the integrated resource input through the input means from the user , and the User interface processing unit that acquires search conditions for the database, what operation the acquired input operation performs for which database or the analysis service , and the acquired search condition for which database for Operation information indicating what kind of search condition is specified, symbol interpretation means for interpreting the integrated resource by referring to the resource integration information, and setting information for making the database usable Based on the address included in the database access information, the request is transmitted to the database server through the Internet, and based on the operation procedure information included in the database access information, a request representing the operation related to the database represented by the operation information is generated. , based on the generated the request to the address contained in the database access information sent to the database server via the Internet, a database access means for receiving a response to it, the analysis service Setting information for allowing use on the basis of the address contained in the analysis service access information and sends to the analysis service server through the Internet, based on the operation procedure information included in the analysis service access information, the operation An analysis that generates a request representing an operation related to the analysis service represented by the information, transmits the generated request to the analysis service server through the Internet based on an address included in the analysis service access information, and receives a response to the request Service access means, and operation result display means for causing the display means to display an operation result for the database or the analysis service based on the received response.

The invention according to claim 2, in addition to the characteristics of the invention according to claim 1 or 2, stores the operation object symbol representing an operation object to be operated with respect to the database or the analysis service on the display unit An operation object symbol storage means that further displays the operation object symbol stored in the operation object symbol storage means on the display means, and the user interface processing section The operation information is obtained by further using the operation object symbol.

The invention according to claim 3, in addition to the features of the invention described in claim 2, the response to which the database access means or the analyzing service access means has received, as a target of operation on the database or the analysis service An operation object symbol generating unit that generates an operation object symbol representing the object on the display unit when the predetermined object is represented, and further stores the generated operation object symbol in the operation object symbol storage unit; It is characterized by having.

In addition to the features of the invention described in claim 2 or 3 , the invention described in claim 4 is an operation object information storage means for storing information related to the operation object, and the operation in response to an instruction from the user. Operation object information display means for displaying the information related to the object on the display means is further provided.

The invention described in claim 5 is characterized in that, in addition to the features of the invention described in claim 4 , the object symbols are classified into categories including proteins, nucleic acids, and groups thereof.

The invention according to claim 6, in addition to the features of the invention described in any one of claims 1 to 5, the database symbol, for receiving a predetermined input operation associated with the predetermined operation The analysis service symbol has a predetermined area, the analysis service symbol has a predetermined area for receiving a predetermined input operation associated with the predetermined operation, and the user interface processing unit has the database symbol or the analysis An operation corresponding to the predetermined input operation on the predetermined area of the service symbol is acquired as operation information.

According to a seventh aspect of the invention, in addition to the features of the invention of the sixth aspect, the user interface processing unit is configured such that the operation object symbol is associated with a predetermined region of the database symbol or the analysis service symbol. Thus, operation information in which the operation object symbol is associated with an operation corresponding to the predetermined region of the database symbol or the analysis service symbol is acquired.

In addition to the features of the invention described in claim 1, the invention described in claim 8 generates the resource integration information and the resource integration symbol based on an instruction input from a user, and generates the resource integration It further comprises resource editing means for further storing information and resource integration symbols in the resource integration information storage means and the resource integration symbol storage means, respectively.

In the invention described in claim 9 , in addition to the features of the invention described in claim 7 , the integrated symbol has a predetermined area for receiving a predetermined input operation associated with the predetermined operation, The user interface processing unit further acquires, as operation information, an operation corresponding to the predetermined input operation on the predetermined area of the integrated symbol.

According to a tenth aspect of the present invention, in addition to the features of the invention according to the ninth aspect, the user interface processing unit associates the operation object symbol with a predetermined region of the integrated symbol, thereby the integrated symbol. The operation information in which the operation object symbol is associated with the operation corresponding to the predetermined area is acquired.

According to an eleventh aspect of the present invention, in addition to the features of the invention according to the ninth or tenth aspect, at least one of the database symbol, the analysis service symbol, and the integrated symbol is for receiving a predetermined input operation. The predetermined area is sequentially changed according to the input operations performed so far.

The invention described in claim 12 is characterized in that, in addition to the features of the invention described in any one of claims 1 to 11 , the database is a biological database, and the analysis service is a biological analysis service. Features.

Invention according to claim 13, in addition to the characteristics of the invention defined in any one of claims 2 12, the operation result display means, the response from a plurality of the analysis service for the same control object, The display means is simultaneously displayed by superimposing a plurality of characteristic portions for the same operation object displayed on the display means.

The invention described in claim 14 is a computer-operated database and analysis service connected through the Internet to one or more database servers that respectively provide databases and one or more analysis service servers that provide analysis services. In the operation integrated system, database access information representing operation procedure information including an address for connecting to each database server via the Internet and interface information and data format for using each database is stored in the computer. a step to be stored, representing the database on the screen has an input field for inputting a search condition, and a database symbol for receiving an operation on the database, The computer stores analysis service access information representing operation procedure information including a step of storing in the computer, an address for connecting to each of the analysis service servers, and interface information and data format for using each of the analysis services. A step of storing, a step of storing, in a computer, resource integration information relating to integrated resources in which a plurality of databases and resources of the analysis service are associated in a predetermined access order and operation order, and the analysis service is represented on the screen. Storing an analysis service symbol for accepting an operation for the analysis service in a computer, displaying the integrated resource on the screen, and operating the integrated resource Storing a resource integration symbol to be received in a computer; displaying the database symbol, the analysis service symbol, and the resource integration symbol on the screen by the computer; and the database input from the user and the analysis Steps for obtaining the input operation for the service or the integrated resource and the search condition for the database by the computer, and what operation the acquired input operation performs for which database or the analysis service , And the acquired search condition refers to the operation information indicating which search condition is specified for which database, and the integrated resource is referred to the resource integration information for the computer. And the operation procedure information included in the database access information is transmitted to the database server via the Internet based on the address included in the database access information. And generating a request representing the operation related to the database represented by the operation information, transmitting the generated request to the database server through the Internet based on the address included in the database access information, and responding to the request. receiving a computer, the Internet based on the setting information to be able to use the analysis service address included in the analysis service access information Through transmitted to the analysis service server, on the basis of operation procedure information included in the analysis service access information, generates a request that represents an operation related to the analysis service to which the operation information is represented, the analyzing generated the request A step of transmitting to the analysis service server through the Internet based on the address included in the service access information and receiving a response to the server by the computer, and an operation result for the database or the analysis service based on the received response. And a step of displaying the display means by a computer.

The invention described in claim 15 is a computer-operated database and analysis service connected through the Internet to one or more database servers and database analysis services that respectively provide databases. In the operation integrated system, database access information representing operation procedure information including an address for connecting to each of the database servers via the Internet and interface information and data format for using each of the databases in the computer a step of storing in the computer, indicates the database on the screen has an input field for inputting a search condition, and data for accepting an operation on the database Sushinboru, and storing the to the computer, each address for connection to the analysis service server, and analyzing service access information indicating the operation procedure information including information and data format interface for using each of the analysis service Storing a plurality of the database and the analysis service resources in a computer in a predetermined access order and an operation order, and storing the resource integration information on the computer on the screen. A step of causing the computer to store an analysis service symbol for accepting an operation on the analysis service, and displaying the integrated resource on the screen and displaying the integrated resource. Storing a resource integration symbol that accepts an operation on a computer in a computer, displaying the database symbol, the analysis service symbol, and the resource integration symbol on the screen by a computer, and input from the user, The step of acquiring the input operation for the database, the analysis service, or the integrated resource , and the search condition for the database by a computer , and the input operation acquired for any database or the analysis service Refer to the resource integration information for the integrated resource for the operation information that indicates what kind of search condition is specified for which database the acquired search condition is for the relevant database And transmitting the setting information for making the database usable by the computer to the database server through the Internet based on the address included in the database access information, and included in the database access information. Based on the operation procedure information, a request representing an operation related to the database represented by the operation information is generated, and the generated request is transmitted to the database server through the Internet based on an address included in the database access information, receiving a response by the computer for it, based on the setting information to be able to use the analysis service address included in the analysis service access information the Transmitted to the analysis service server through the Internet, based on the operation procedure information included in the analysis service access information, generates a request that represents an operation related to the analysis service to which the operation information is represented, the analyzing generated the request A step of transmitting to the analysis service server through the Internet based on the address included in the service access information and receiving a response to the server by the computer, and an operation result for the database or the analysis service based on the received response. And causing the display means to display by a computer.

  As described above, the system according to the present invention allows the user to operate the unified interface provided by the system, so that the user can easily and quickly do not need specific knowledge about resources such as DB and AS. It is possible to obtain an effect that resources can be used. In addition, since the user can set an interface suitable for his / her purpose, there is an effect that it is possible to construct an environment that uses resources optimal for the user. In addition, there is an effect that a single operation can access a plurality of analysis servers or use a plurality of arrays simultaneously in the analysis service, which can greatly save the user and work efficiently. . Furthermore, the simultaneous display of the service results and the display on the three-dimensional structure can provide an effect that the user can study the correlation between services and the three-dimensional structure. In particular, the present invention, when used for information biology education, can reduce education content and education time in that it can concentrate on biology without requiring detailed computer knowledge. Is obtained.

  An operation integration system 100 for a database (hereinafter abbreviated as DB) and an analysis service (hereinafter abbreviated as AS (Analysis Service)) according to an embodiment of the present invention will be described with reference to the drawings. First, the configuration of the DB and AS operation integration system 100 will be described. FIG. 1 is a system configuration diagram showing a configuration of a DB and AS operation integration system 100. The DB and AS operation integration system 100 is mainly composed of a DB related unit 20, an analysis service related unit 30, an object related unit 40, a resource related unit 50, and a user interface (hereinafter abbreviated as UI) related unit 60. Is done. The DB related unit 20 is a subsystem that performs processing related to a database, and further includes a DB processing unit 2, a DB symbol storage unit 2A, a DB access unit 3, and a DB access information storage unit 3A. The analysis service related unit 30 is a subsystem that performs processing related to the analysis service, and further includes an AS processing unit 4, an AS symbol storage unit 4A, an AS access unit 5, and an AS access information storage unit 5A. The object-related unit 40 is a subsystem that performs processing related to an operation object that represents an object to be operated by the DB and AS, and further includes an object management unit 6, an operation object information storage unit 6A, and an operation object symbol storage unit 6B. Consists of The resource related unit 50 is a subsystem for integrating and handling a plurality of DB and AS resources, and further includes a resource management unit 7, a resource integration information storage unit 7A, and a resource integration symbol storage unit 7B. . The UI-related unit 60 is a subsystem that inputs and outputs information with the user, and further includes a UI processing unit 8, an input unit 9A, and a display unit 9B. Below, each component is demonstrated in detail.

  The DB and AS operation integration system 100 typically uses a computer including a CPU, a memory, a storage device such as a hard disk drive, a network interface, and a user interface as a platform. In the DB and AS operation integration system 100, components that perform information processing are implemented by loading an application stored in the hard disk drive onto the memory and executing it by the CPU. The DB and AS operation integration system 100 is also connected to the first DB server 71, the second DB server 72, the first AS server 81, and the second AS server 82 through the Internet.

  The DB processing means 2 is a component for providing a DB search service with a unified interface, and is typically in the form of a CPU executing an application that realizes the function. The DB symbol storage means 2A is a component for storing a DB symbol form and function for representing a DB on the screen and receiving an operation on the DB in order to provide a unified interface to the user. Typically, the hard disk drive stores the DB symbol data. Regarding the input, the DB processing unit 2 interprets the input operation representing the screen operation on the DB symbol received from the UI processing unit 8 as operation information representing what kind of actual operation has been commanded. Regarding the output, the DB processing means 2 reads the DB symbol from the DB symbol storage means 2A, configures the DB symbol based on the DB symbol, and causes the UI related unit 60 to display it.

  The DB access means 3 is a component for individually accessing various DBs whose operation procedures such as interface and data format may be different, and is typically a CPU that executes an application that realizes the function. And a network interface that provides connection to the Internet. The DB access information storage unit 3A is a component for storing DB access information including various DB addresses and operation procedure information (operation command method, input data format, output data format, operation order, etc.). Typically, the hard disk drive stores the DB access information. The DB access means 3 reads the DB access information from the DB access information storage means 3A, and accesses the DB server on the Internet at the address included in the DB access information. Based on the operation procedure information included in the DB access information, the DB access means 3 transmits an operation request including a search condition to a DB search service provided by the DB server, and includes a search result for the DB server ( A response of a first DB server 71, a second DB server 72, etc., which will be described later, is received.

  The AS processing means 4 is a component for providing a user with a unified interface analysis service, and typically has the form of a CPU executing an application that realizes the function. The AS symbol storage means 4A is a component for storing the AS symbol form and function for representing the AS on the screen and accepting operations on the AS in order to provide a unified interface to the user. Typically, the hard disk drive stores the AS symbol data. Regarding the input, the AS processing means 4 interprets the input operation representing the screen operation for the AS symbol received from the UI processing unit 8 as operation information representing what kind of actual operation is instructed. As for output, the AS processing unit 4 reads out the AS symbol from the AS symbol storage unit 4A, configures the AS symbol based on the AS symbol, and causes the UI related unit 60 to display the AS symbol.

  The AS access means 5 is a component for individually accessing various ASs whose operation procedures such as interface and data format may be different, and is typically a CPU that executes an application that realizes the function. And a network interface that provides connection to the Internet. The AS access information storage means 5A is a component for storing AS access information including various AS addresses and operation procedure information (operation command method, input data format, output data format, operation order, etc.). Typically, the hard disk drive stores the AS access information. The AS access means 5 reads the AS access information from the AS access information storage means 5A, and accesses the AS server on the Internet at the address included in the AS access information. The AS access means 5 transmits an operation request including an analysis condition to an analysis service provided by the AS server based on the operation procedure information included in the AS access information, and an AS server (described later) including an analysis result for the analysis request. , The first AS server 81, the second AS server 82, etc.).

The object management means 6 is a component for managing an operation object symbol representing an operation object to be operated on the DB or AS on the screen, and typically executes an application that realizes the function. It is a form of CPU. Examples of operation objects for DB or AS include proteins, nucleic acids, and groups thereof. The operation object information storage means 6A is a component for storing information related to the operation object, and is typically in the form of a hard disk drive that stores the operation object information. The information about the operation object includes various properties. For example, if it is a protein, it has a three-dimensional structure, if it is a nucleic acid, the position information (nucleic acid map) of the protein in the nucleic acid, It is information corresponding to the type of object, such as the object to be configured and the order in which the AS is operated. As detailed information, for proteins and nucleic acids, sequences, names, descriptions indicating their functions, biological species, classification on phylogenetic trees, coordinate information of three-dimensional structures, and the like can be stored. By defining a group, it becomes possible to handle a plurality of proteins and the like, and the user's operation can be made very simple. The operation object information storage means 6A preferably stores operation objects by dividing them into categories of proteins, nucleic acids, and groups thereof. The operation object symbol storage means 6B represents the operation object on the screen and provides an operation object symbol form for accepting an operation on the DB or AS using the operation object in order to provide a unified interface to the user. It is a component for storing functions, and is typically in the form of a hard disk drive that stores data of its operation object symbols. The object management unit 6 receives information on the operation object from the operation object information storage unit 6A in response to a request for object information display from the UI related unit 60, and passes it to the UI related unit 60 for display. Regarding the input, the object management means 6 receives an input operation representing a screen operation for the operation object symbol from the UI related unit 60, and interprets it as operation information indicating what kind of actual operation has been commanded. Regarding output, the object management unit 6 reads out the operation object symbol from the operation object symbol storage unit 6B, configures the operation object symbol based on the operation object symbol, and causes the UI related unit 60 to display it.

  The resource management means 7 is a component for integrating and handling a plurality of DB and AS resources, and is typically in the form of a CPU executing an application that realizes the function. The resource integration information storage means 7A is a resource integration information that indicates which resource is operated in what access order and operation order so that resources including a plurality of DBs and ASs can be used in a single operation. Is typically in the form of a hard disk drive that stores the resource integration information. The resource integration symbol storage means 7B is a component for managing the resource integration symbols representing the integrated resources on the screen, and is typically in the form of a hard disk drive that stores the resource integration symbols. . As for input, the resource management means 7 receives an input operation representing a screen operation for the resource integration symbol from the UI related unit 60, interprets what integrated entity operation is commanded, and which DB or This is interpreted as specific operation information indicating what kind of operation is performed in what access order and operation order for the AS. Regarding the output, the resource management means 7 reads out the resource integration symbol from the resource integration symbol storage means 7B, configures the resource integration symbol based on the resource integration symbol, and causes the UI related unit 60 to display it.

  The UI processing unit 8 is a component for performing information processing for input / output of information with a user. Typically, a keyboard / mouse interface is used as an input interface, and a symbol is used as an output interface. It is a form of a CPU and a graphics card that execute an application to be generated. The UI processing unit 8 receives an input such as an operation through the input unit 9A from the user, and sends information related to the input operation based on the input to the DB related unit 20, the AS related unit 30, the object related unit 40, or the resource related unit 50. Deliver. In addition, the UI processing unit 8 displays the DB symbol, the AS symbol, the operation object symbol, or the resource integration symbol on the display unit 9B.

  In addition, the process regarding symbols, such as DB symbol, AS symbol, operation object symbol, and resource integration symbol, is specifically performed as follows. First, as the data of each symbol, graphics data for representing the symbol on the screen and text data of characters displayed on the symbol are stored. Further, when a predetermined input operation is accepted for the entire symbol or a specific area, the position information of the area and the format / type of data input to the position are stored. When data is input from a user through a symbol, an input operation using a screen or a keyboard or a mouse is input from the UI processing unit 8. If the input operation was a click on the screen, it is determined whether there is a symbol displayed at the clicked position, and if there is a symbol, whether a specific area within the symbol was clicked. Judgment is made. If there is text input from the keyboard, it is determined that the input is commanded to the cursor position on a predetermined input field on the screen (or a symbol on the screen) and is associated with the function of the input field. Text data is acquired. This makes it possible to know what input operation (positioning by click, text input, etc.) was performed for which symbol, and collating it with the symbol data to input the actual operation information. Is interpreted. On the other hand, when a symbol is displayed on the screen, the symbol is generated from the graphic data of the symbol based on the type and position of the symbol to be displayed, and is arranged on the screen.

  The first DB server 71 and the second DB server 72 are servers that provide a Web site that provides a database search service on the Internet, and are typically Web servers that cooperate with a database management system. Since one or more DB servers can be connected to the DB and AS operation integration system 100, the two DB servers are shown as the first DB server 71 and the second DB server 72 as representatives. The first AS server 81 and the second AS server 82 are servers that provide websites that provide analysis services on the Internet, and are typically web servers that cooperate with an analysis system. Since one or more AS servers can be connected to the DB and AS operation integration system 100, the two AS servers are shown as a first AS server 81 and a second AS server 82 as representatives.

The operation of the DB and AS operation integration system 100 will now be described with reference to the drawings. First, the terms are explained.
Input operation: An operation for specifying an operation target performed by the user through the input unit 9A, such as coordinate input by mouse point-and-click, character input from a keyboard, or the like.
Operation information: a substantive operation that the user intends to instruct through an input operation, such as a search instruction based on a specific search condition for a specific DB.
Operation request: This is an operation command transmitted from the DB / AS operation integration system 100 to the DB server or AS server via the Internet.
Response: Information on the result of the operation of the DB server or AS server, which is transmitted to the DB and AS operation integration system 100 in response to the operation request.
DB symbol: A symbol for representing DB on the display means 9B, and preferably a search keyword input field is provided.
AS symbol: a symbol for representing AS on the display means 9B. FIG. 2 to FIG. 4 are operation flow diagrams in the operation mode using the DB symbol and AS symbol of the DB and AS operation integration system 100.
Manipulation object: An object to be manipulated by DB or AS, such as protein, nucleic acid, or a group thereof.
Operation object symbol: a symbol for representing an operation object on the display means 9B.
Resource: A resource for performing search or analysis, such as DB or AS.
Resource integration symbol: a symbol for integrating a plurality of DBs and ASs on the display means 9B.

  First, the operation in the first embodiment using DB symbols and AS symbols will be described. 2 to 4 are operation flowcharts in the first embodiment using the DB symbol and AS symbol of the DB and AS operation integration system 100. FIG. 9 to 14 are image diagrams of display screens at predetermined steps in the operation flow. In the initial state, the DB processing unit 2, the AS processing unit 4, the object management unit 6, and the resource management unit 7 are respectively connected to the DB symbol storage unit 2A, the AS symbol storage unit 4A, the operation object symbol storage unit 6B, and the resource integration symbol. The DB symbol, AS symbol, operation object symbol, and resource integration symbol stored in the storage unit 7B are displayed on the display unit 9B (step S101). FIG. 8 is an image diagram of an initial screen on which DB symbols, AS symbols, operation object symbols, and resource integration symbols are displayed. In FIG. 9, protein (DB1) and structure (DB2) are used as DB symbols, transmembrane portion prediction (AS1), sugar chain binding site prediction (AS2), transport destination prediction (AS3), and function prediction (AS4) as AS symbols. ), Three-dimensional structure prediction (AS5), phosphate binding site prediction (AS6), and signal peptide prediction (AS7) are protein 1 (PR1), protein 2 (PR2), and nucleic acid 1 (NA1) as operation object symbols. , Nucleic acid 2 (NA2), group 1 (GR1), and group 2 (GR2), and protein DB & transmembrane portion prediction (RI) are displayed as resource integration symbols. These symbols are associated with each other by dragging and dropping them on the display means 9B, or those having an input field are input there, thereby allowing the user to input an operation command or the like. Can be accepted. In the following description, since the operation object symbol and the resource integration symbol need not be displayed on the initial screen, the description will be continued with reference to a diagram in which they are not displayed. The DB represented by the DB symbol DB1 is provided by the first DB server 71, the DB represented by the DB symbol DB2 is provided by the second DB server 72, the AS represented by the AS symbol AS1 is provided by the first AS server 81, and the AS symbol AS2 The AS represented by is assumed to be provided by the second AS server 82.

  Next, the UI processing unit 8 acquires a search condition input operation for the DB symbol input from the input unit 9A by the user (step S103). FIG. 10 is an image diagram of a screen in which a search condition is input to the DB symbol. In FIG. 10, “Cancer” is input to the DB symbol DB1 as a search condition. The DB processing means 2 interprets the search condition input operation as operation information related to the database (step S105). That is, the DB processing means 2 interprets that the search keyword “Cancer” has been input to the DB represented by the DB symbol DB1. At this time, an input field for inputting additional search conditions may be displayed so that more detailed search conditions can be set. Next, the DB access unit 3 collates the operation information with the DB access information read from the DB access information storage unit 3A, generates an operation request, and transmits it to the address of the first DB server 71 (step S107). The DB access information represents an operation procedure such as an interface for accessing the DB and a data format for each individual DB. By using DB access information, the difference in the operation procedure of DBs with different interfaces, data formats, etc. is absorbed by the DB and AS operation integration system 100, and various DBs are accessed without making the user aware of the difference. It becomes possible. That is, the user operates the symbol operation method of the DB and AS operation integration system 100, the DB access means 3 adjusts the operation information input from the user based on the DB access information, and the first DB server 71 interprets it. Change to a format that can be used to generate an operation request. Then, the DB access unit 3 transmits an operation request to the first DB server 71 via the Internet. Some DBs require login by entering a user name and password at the time of use, or various settings at the time of use. The DB access means 3 stores in advance setting information for enabling use of such a DB and transmits it to the first DB server 71 so that the user does not have to perform such setting work. , DB can be made available. This eliminates the need for the user to perform troublesome routine operations, and allows the user to efficiently operate the DB.

The first DB server 71 that has received the operation request executes a DB search service in accordance with the search condition included in the operation request, and transmits the search result as a response to the DB and AS operation integration system 100 (step S109). Here, a protein that hits the keyword “Cancer” is searched, and the search result is transmitted to the operation integration system 100 of DB and AS. The DB access means 3 receives the response and causes the UI processing unit 8 to display an operation result (here, a search result) based on the response (step S111). FIG. 11 is an image diagram of a screen on which the search result list LIST is displayed. Three proteins are displayed in the search result list LIST. A check column for selection is displayed at the beginning of each protein name. Here, when the user selects “NP — 009225”, the UI processing unit 8 interprets the input operation of selection from the input unit 9A as operation information (step S113). That is, it is interpreted that the detailed information for the protein “NP — 009225” is requested. Next, the DB access means 3 collates the operation information for requesting detailed information with the DB access information read from the DB access information storage means 3A, generates an operation request, and transmits it to the address of the first DB server 71 ( Step S115). The first DB server 71 receives the operation request, executes the DB search service in accordance with the information request included therein, and transmits the search result information as a response (step S117). The DB access unit 3 receives the response, and causes the UI processing unit 8 to display the operation result based on the response (step S119). The operation object may be displayed before displaying the search result information. FIG. 12 is an image diagram of a screen on which detailed information RES1 about the protein “NP — 009225” is displayed. The analysis result RES1 may include a link to another DB or AS, a link to a term explanation page, or the like. Next, when the response represents an object to be operated on the DB or AS, the operation object management unit 6 generates an operation object representing the object, and the operation object information storage unit 6A stores the search result information as object information. (Step S121). Here, the search result is the protein “NP — 009225”, which is an operation target of DB or AS, and therefore an operation object representing it can be generated. The generated operation object is displayed as an operation object symbol. FIG. 13 is an image diagram of a screen on which the operation object symbol PR3 of the protein “NP_009225” is generated and displayed. Preferably, when the operation object symbol PR3 is double-clicked, detailed information on the protein “NP_009225” shown in FIG. 11 is displayed.

  A procedure for using AS using the DB search result will now be described. The UI processing unit 8 acquires an input operation by associating the operation object input from the input unit 9A by the user with the AS symbol (step S123). FIG. 14 is an image diagram of a screen in which the operation object is associated with the AS symbol. On the screen, the operation object symbol PR3 of the protein “NP — 009225” is overlapped by being dragged and dropped on the membrane passage portion prediction AS symbol AS1. The AS processing means 4 interprets an input operation accompanied by an association by superimposing these symbols as operation information (step S125). That is, the AS processing means 4 interprets that the analysis service by the membrane passage portion prediction AS of the protein “NP_009225” is requested by the user. At this time, an input field for inputting additional analysis conditions may be displayed so that more detailed analysis conditions can be set. The AS access means 5 collates the operation information with the AS access information read from the AS access information storage means 5A, generates an operation request, and sends it to the address of the first AS server 81 (step S127). That is, the AS access means 5 generates an operation request in a format that can be interpreted by the first AS server 81 for analyzing the protein “NP_009225” by the transmembrane portion prediction AS, and transmits it to the address of the first AS server 81. Note that, as in the case of the above-described DB, some ASs require login by entering a user name and password at the time of use, or various settings at the time of use. The AS access means 5 stores in advance setting information for enabling the use of such AS, and transmits it to the first AS server 81 so that the user does not have to perform such setting work. AS can also be made available. This eliminates the need for the user to perform cumbersome routine operations and allows the user to operate the AS efficiently. The first AS server 81 receives the operation request, executes the analysis service according to the analysis included therein, and transmits the analysis result as a response (step S129). The AS access means 5 receives the response, and the UI processing unit 8 Based on this, the operation result is displayed (step S131). FIG. 15 is an image diagram of a screen on which the analysis result RES2 of the transmembrane portion prediction for the protein “NP — 009225” is displayed. The analysis result RES2 may include a link to another DB or AS, a link to a term explanation page, or the like. When the response represents an object to be operated on the DB or AS, the object management means 6 generates an operation object representing the object, and the operation object information storage means 6A stores the search result information as object information. it can. Further, detailed information on the analysis result can be acquired from the first AS server 81 and displayed in association with the operation object. This is the end of the description of the operation in the first embodiment using the DB symbol and the AS symbol.

  Next, an operation in the second embodiment using the operation object symbol and the resource integration symbol will be described. 5 to 6 are operation flow diagrams in the second embodiment using the operation object symbol and the resource integration symbol of the operation integration system 100 of DB and AS. In the third embodiment, the resource integration symbol is obtained by integrating one DB and one AS. First, the DB processing unit 2, the AS processing unit 4, the object management unit 6, and the resource management unit 7 are respectively a DB symbol storage unit 2A, an AS symbol storage unit 4A, an operation object symbol storage unit 6B, and a resource integrated symbol storage unit. The symbol stored in 7B is displayed on the display means 9B (step S201). FIG. 9 is an image diagram of an initial screen on which DB symbols, AS symbols, operation object symbols, and resource integration symbols are displayed. In FIG. 9, protein DB & transmembrane part prediction (RI) is displayed as a resource integration symbol.

  Next, the UI processing unit 8 acquires an input operation for the resource input by the user from the input unit 9A and associated with the resource integration symbol of the operation object symbol (step S203). FIG. 16 is an image diagram of a screen in which the operation object symbol NA1 of the nucleic acid 1 is associated with the protein DB & transmembrane portion prediction and the resource integration symbol RI. By this operation, the user searches for a protein corresponding to the nucleic acid 1, and tries to analyze a transmembrane portion prediction for the protein searched for. The object management means 6 interprets the input operation as operation information related to the operation object (step S205). That is, it is interpreted that an operation related to the nucleic acid 1 has been input. The resource management unit 7 interprets the input operation as operation information related to the resource (DB or AS) (step S207). That is, it is interpreted that an operation related to the integrated resource of protein DB & transmembrane portion prediction is input. The resource management unit 7 specifies integrated operation information by associating the above operation information with the resource integration information stored in the resource integration information storage unit 7A (step S209). Here, an integrated operation for further analysis by AS1 based on the search result of DB1 is defined in the resource integration information. Next, the UI processing unit 8 inputs additional search conditions for the DB as operation information as necessary (step S211). The DB access unit 3 compares the operation information with the DB access information read from the DB access information storage unit 3A, generates an operation request, and transmits the operation request to the address of the first DB server 71 (step S213). The first DB server 71 executes a search service according to the search condition included in the operation request, and transmits the search result as a response to the DB and AS operation integration system 100 (step S215). The DB access means 3 receives the response, and if it represents an object to be operated on the DB or AS, the operation object management means 6 generates an operation object representing it (step S217). The UI processing unit 8 inputs an additional analysis condition for the AS as operation information as necessary (step S219). The AS access means 5 collates the operation information with the AS access information read from the AS access information storage means 5A, generates an operation request, and sends it to the address of the first AS server 81 (step S221). The first AS server 81 executes the analysis service according to the analysis conditions included in the operation request, and transmits the analysis result as a response (step S223). When the AS access means 5 receives the response and represents an object to be operated on the DB or AS, the operation object management means 6 generates an operation object representing it (step S225). The UI processing unit 8 displays the operation result on the display unit 9B based on the response (step S227).

  Next, the operation in the third embodiment using the operation object symbol and the resource integration symbol will be described. FIGS. 7 to 8 are operation flowcharts in the third embodiment using the operation object symbol and the resource integration symbol of the DB and AS operation integration system 100. In the third embodiment, the resource integration symbol is an integration of two ASs. First, the DB processing unit 2, the AS processing unit 4, the object management unit 6, and the resource management unit 7 are respectively a DB symbol storage unit 2A, an AS symbol storage unit 4A, an operation object symbol storage unit 6B, and a resource integrated symbol storage unit. The symbol stored in 7B is displayed on the display means 9B (step S301). FIG. 8 is an image diagram of an initial screen on which DB symbols, AS symbols, operation object symbols, and resource integration symbols are displayed. In FIG. 9, protein DB & transmembrane part prediction (RI) is displayed as a resource integration symbol.

  Next, the UI processing unit 8 acquires an input operation for a resource input from the input unit 9A by the user and associated with the resource integration symbol of the operation object symbol (step S303). FIG. 17 is an image diagram of a screen on which the transmembrane portion prediction & sugar chain binding site prediction of the operation object symbol PR1 of protein 1 is associated with the resource integration symbol RI2. By this operation, the user intends to analyze the transmembrane portion prediction and the sugar chain binding site prediction for protein 1. The object management means 6 interprets the input operation as operation information related to the operation object (step S305). The resource management unit 7 interprets the input operation as operation information related to the resource (DB or AS) (step S307). The resource management unit 7 associates the above operation information with the resource integration information stored in the resource integration information storage unit 7A, thereby obtaining integrated operation information (here, the analysis result of AS1 and the analysis result of AS2). To be compared (step S309). The UI processing unit 8 inputs an additional analysis condition for the AS as operation information as necessary (step S311). The AS access unit 5 compares the operation information with the AS access information read from the AS access information storage unit 5A, generates an operation request, and transmits it to the address of the first AS server 81 (step S313). The first AS server 81 executes the analysis service according to the analysis conditions included in the operation request, and transmits the analysis result as a response (step S315). When the AS access means 5 receives the response and represents an object to be operated on the DB or AS, the operation object management means 6 generates an operation object representing it (step S317). The UI processing unit 8 inputs an additional analysis condition for the AS as operation information as necessary (step S319). The AS access means 5 collates the operation information with the AS access information read from the AS access information storage means 5A, generates an operation request, and transmits it to the address of the second AS server 82 (step S321). The second AS server 82 executes the analysis service according to the analysis conditions included in the operation request, and transmits the analysis result as a response (step S323). Here, it is assumed that the second AS server 82 provides a sugar chain binding site prediction analysis service, for example. When the AS access means 5 receives the response and represents an object to be operated on the DB or AS, the operation object management means 6 generates an operation object representing it (step S325). The UI processing unit 8 simultaneously displays the operation results on the display unit 9B based on the responses of steps S217 and S225 (step S327). Here, responses from a plurality of the analysis services for the same operation object are displayed on the display unit at the same time by overlapping them as a plurality of characteristic portions for the same operation object displayed on the screen. FIG. 18 is an amino acid sequence table in which characteristic portions are superimposed. In the figure, the transmembrane portion analyzed by the transmembrane portion analysis service, the N-type sugar chain binding site and the O-type sugar chain binding site analyzed by the sugar chain binding site prediction analysis service are superimposed on the sequence of protein NP_015097. Is displayed. Thus, by simultaneously displaying the operation results for the same operation object, the operation results can be compared on one screen. As described above, a plurality of analysis results can be obtained using a plurality of analysis services for one protein (nucleic acid) operation object. For specific analysis (eg, transmembrane region prediction, sugar chain binding site prediction, phosphate binding site prediction), the analysis result that the specific site of protein amino acid sequence (base sequence of nucleic acid) has characteristics is obtained. It is done. Preferably, the plurality of analysis results are displayed on one screen. For example, the array is displayed first, and the result of the transmembrane region is displayed as a symbol in the next row. For example, if the result is the fifth to tenth range, the symbol is displayed below the fifth to tenth range of the array. The result of the sugar chain binding site is displayed in the next line. In this way, by displaying the analysis results for one array in the lower row, it is possible to see a plurality of analysis results superimposed on one screen. As a result, it is possible to obtain an effect of comparing and examining the relationship between users and analysis results in a list.

  Note that various operations including the above-described operations can be called through a hierarchical menu displayed on the screen. FIG. 18 is an example of a menu configuration diagram of an operation menu for displaying and editing object information. Object functions can be displayed / edited using the functions shown in each level of the operation menu. FIG. 19 is an example of a menu configuration diagram of an operation menu for interface customization. By utilizing the functions shown in each level of the operation menu, the interface can be customized so that the user can easily use it.

  The above embodiment can be variously modified as follows. By registering a plurality of proteins and nucleic acids in a group of operation object symbols, a plurality of analyzes can be performed in a single operation. In this case, a plurality of proteins (or nucleic acid objects) are combined into one group of operation objects. This group of operation objects is generated by associating with the analysis service on the user interface. When an operation is performed on an operation object symbol including a plurality of objects, the object management means 6 transmits an operation request to the AS for each protein object (or nucleic acid object) in the operation object representing the group. Thus, AS can be used for a plurality of objects in one operation.

  Since there is a structure DB in the DB, sequence information and three-dimensional structure information can be acquired when a protein is acquired as a search result from the structure DB. When AS is performed on a protein manipulation object containing this information, the amino acid sequence of the protein (nucleic acid sequence of the nucleic acid) is determined for specific analysis (eg, transmembrane region prediction, sugar chain binding site prediction, phosphate binding site prediction). An analysis result that a specific part of the base sequence) has a characteristic is acquired. When there is three-dimensional structure information, when the analysis result is displayed on the three-dimensional structure, the part can be displayed on the three-dimensional structure (for example, by giving a specific color to the part to make it stand out) Can also be.) Thereby, the analysis result by the analysis service can be confirmed on the display screen of the three-dimensional structure. Thereby, the user can obtain an effect of being able to consider the correlation between the analysis result and the three-dimensional structure of the protein.

  With respect to the nucleic acid sequence, sequence information at each step such as transcription, splicing, and translation may be stored, and the sequence at an arbitrary step may be displayed in response to a request from the user.

1 is a system configuration diagram of a DB and AS operation integration system 100 according to an embodiment of the present invention. FIG. It is an operation | movement flowchart in 1st Embodiment using DB symbol and AS symbol of the operation integration system 100 of DB and AS. FIG. 6 is an operation flow diagram in the first embodiment using the DB symbol and AS symbol of the DB and AS operation integration system 100, and is a continuation of FIG. FIG. 6 is an operation flowchart in the first embodiment using the DB symbol and AS symbol of the DB and AS operation integration system 100, and is a continuation of FIG. It is an operation | movement flowchart in 2nd Embodiment using the operation object symbol and resource integration symbol of operation integration system 100 of DB and AS. FIG. 6 is an operation flow diagram in the second embodiment using the operation object symbol and the resource integration symbol of the operation integration system 100 of DB and AS, and is a continuation of FIG. 5. It is an operation | movement flowchart in 3rd Embodiment using the operation object symbol and resource integration symbol of operation integration system 100 of DB and AS. FIG. 10 is an operation flow diagram in the third embodiment using the operation object symbol and the resource integration symbol of the DB and AS operation integration system 100, and is a continuation of FIG. It is an image figure of the initial screen on which DB symbol, AS symbol, operation object symbol, and resource integration symbol were displayed. It is an image figure of the screen where search conditions were inputted into DB symbol DB1. It is an image figure of the screen where the search result list LIST was displayed. It is an image figure of the screen on which the detailed information RES1 about protein "NP_009225" is displayed. It is an image figure of the screen where the operation object symbol PR3 of protein “NP_009225” is generated and displayed. It is an image figure of the screen associating the operation object with the AS symbol. It is an image figure of the screen on which the analysis result RES2 of transmembrane part prediction about protein "NP_009225" is displayed. It is an image figure of the screen associating the operation object with the resource integration symbol. It is an image figure of the screen associating the operation object with the resource integration symbol. It is the amino acid sequence table | surface which superimposed the characteristic part. It is an example of the menu block diagram of the operation menu for the information display / edit of an object. It is an example of the menu block diagram of the operation menu for customization of an interface.

Explanation of symbols

2 DB processing means 2A DB symbol storage means 3 DB access means 3A DB access information storage means 4 AS processing means 4A AS symbol storage means 5 AS access means 5A AS access information storage means 6 Object management means 6A Operation object information storage means 6B Operation Object symbol storage means 7 Resource management means 7A Resource integrated information storage means 7B Resource integrated symbol storage means 8 UI processing section 9A Input means 9B Display means 20 DB related section 30 Analysis service related section 40 Object related section 50 Resource related section 60 UI related Unit 71 1st DB server 72 2nd DB server 81 1st AS server 82 2nd AS server 100 Operation integration system of DB and AS

Claims (15)

It has an input means for inputting information from a user and a display means for displaying information to the user, and is connected to one or more database servers for providing databases and one or more analysis service servers for providing analysis services, respectively, via the Internet. An integrated system for database and analysis service operation that is made to function by a computer, including an address for connecting to each of the database servers, and interface information and data format for using each of the databases Database access information storage means for storing database access information representing procedure information;
Database symbol storage means for representing the database on the display means, having an input field for inputting a search condition, and storing a database symbol for accepting an operation on the database;
Analysis service access information storage means for storing analysis service access information representing an operation procedure information including an address for connecting to each of the analysis service servers, and interface information and data format for using each of the analysis services When,
Resource integrated information storage means for storing resource integrated information related to integrated resources in which a plurality of the databases and resources of the analysis service are associated in a predetermined access order and operation order;
Analysis service symbol storage means for storing the analysis service symbol for representing the analysis service on the display means and receiving an operation for the analysis service;
Resource integrated symbol storage means for representing the integrated resource on the display means and storing a resource integrated symbol for accepting an operation on the integrated resource;
Symbol display means for displaying the database symbol, the analysis service symbol, and the resource integration symbol on the display means;
A user interface processing unit for obtaining an input operation for the database, the analysis service, or the integrated resource, and a search condition for the database, which are input through the input means from the user;
The acquired input operation indicates what operation is performed on which database or the analysis service, and the acquired search condition indicates what search condition is specified for which database. Symbol interpretation means for interpreting operation information with reference to the resource integration information for the integrated resources;
Setting information for making the database usable is transmitted to the database server through the Internet based on an address included in the database access information, and based on operation procedure information included in the database access information, the operation Database access means for generating a request representing an operation related to the database represented by the information, transmitting the generated request to the database server through the Internet based on an address included in the database access information, and receiving a response to the request ,
Setting information for enabling use of the analysis service is transmitted to the analysis service server through the Internet based on an address included in the analysis service access information, and based on operation procedure information included in the analysis service access information Generating a request representing an operation related to the analysis service represented by the operation information, and transmitting the generated request to the analysis service server through the Internet based on an address included in the analysis service access information, An analysis service access means for receiving the response;
An operation integration system for a database and an analysis service, comprising: an operation result display unit that causes the display unit to display an operation result for the database or the analysis service based on the received response. In the database and analysis service operation integration system according to claim 1 ,
An operation object symbol storage means for storing an operation object symbol representing an operation object to be operated on the database or the analysis service on the display means;
The symbol display means further causes the display means to display the operation object symbol stored in the operation object symbol storage means,
The database and analysis service operation integration system, wherein the user interface processing unit acquires operation information by further using the operation object symbol. In the database and analysis service operation integration system according to claim 2,
When the response received by the database access means or the analysis service access means represents a predetermined object to be operated on the database or the analysis service, an operation object symbol representing the object on the display means is generated. And an operation object symbol generation unit for further storing the generated operation object symbol in the operation object symbol storage unit. In the database and analysis service operation integration system according to claim 2 or 3, an operation object information storage means for storing information about the operation object;
An operation object information display unit for displaying the information on the operation object on the display unit in response to an instruction from the user, further comprising an operation integration system for a database and an analysis service. In the database and analysis service operation integration system according to claim 4,
A database and analysis service operation integration system, wherein the object symbols are classified into categories including proteins, nucleic acids, and groups thereof. In the database and analysis service operation integration system according to any one of claims 1 to 5,
The database symbol has a predetermined area for receiving a predetermined input operation associated with a predetermined operation,
The analysis service symbol has a predetermined region for receiving a predetermined input operation associated with a predetermined operation, and the user interface processing unit is configured to store the database symbol or the predetermined region of the analysis service symbol. An operation integration system for a database and an analysis service, wherein operation corresponding to the predetermined input operation is acquired as operation information. In the database and analysis service operation integration system according to claim 6,
The user interface processing unit associates the operation object symbol with an operation corresponding to the predetermined region of the database symbol or the analysis service symbol by associating the operation object symbol with the predetermined region of the database symbol or the analysis service symbol. An operation integration system for a database and an analysis service, wherein operation information associated with an object symbol is acquired. In the database and analysis service operation integration system according to claim 1,
The resource integration information and the resource integration symbol are generated based on an instruction input from a user, and the generated resource integration information and the resource integration symbol are further stored in the resource integration information storage unit and the resource integration symbol storage unit, respectively. A database and analysis service operation integration system, further comprising resource editing means for storing. In the database and analysis service operation integration system according to claim 7,
The integrated symbol has a predetermined area for receiving a predetermined input operation associated with a predetermined operation,
The database and analysis service operation integration system, wherein the user interface processing unit further acquires, as operation information, an operation corresponding to the predetermined input operation on the predetermined region of the integrated symbol. In the database and analysis service operation integration system according to claim 9,
The user interface processing unit acquires operation information in which the operation object symbol is associated with an operation corresponding to the predetermined region of the integrated symbol by associating the operation object symbol with the predetermined region of the integrated symbol. An integrated operation system for database and analysis service. In the database and analysis service operation integration system according to claim 9 or 10,
At least one of the database symbol, the analysis service symbol, and the integration symbol is configured to sequentially change a predetermined area for receiving a predetermined input operation according to the input operation performed so far. Database and analysis service operation integration system. In the database and analysis service operation integration system according to any one of claims 1 to 11,
The database is a biological database;
A database and analysis service operation integration system, wherein the analysis service is a biological-related analysis service. In the database and analysis service operation integration system according to any one of claims 2 to 12,
The operation result display means causes the display means to simultaneously display responses from the plurality of analysis services for the same operation object as a plurality of characteristic portions for the same operation object displayed on the display means. A database and analysis service operation integration system characterized by the above. Database and analysis service in a computer-operated database and analysis service operation integrated system connected via the Internet to one or more database servers and analysis service servers each providing a database, respectively. The operation integration method of
Storing database access information representing operating procedure information including an address for connecting to each of the database servers via the Internet and interface information and data format for using each of the databases; and
Representing the database on the screen, having an input field for inputting a search condition, and storing a database symbol for accepting an operation for the database in a computer;
Storing in the computer analysis service access information representing operation procedure information including an address for connecting to each of the analysis service servers, and interface information and data format for using each of the analysis services;
Storing, in a computer, resource integration information relating to integrated resources in which a plurality of resources of the database and the analysis service are associated in a predetermined access order and operation order;
Representing the analysis service on a screen and storing an analysis service symbol for accepting an operation for the analysis service in a computer;
Representing the integrated resource on the other surface, and storing a resource integration symbol for accepting an operation for the integrated resource in a computer;
Causing the computer to display the database symbol, the analysis service symbol, and the resource integration symbol on the screen;
Obtaining an input operation for the database, the analysis service, or the integrated resource, and a search condition for the database, which are input by the user;
The acquired input operation indicates what operation is performed on which database or the analysis service, and the acquired search condition indicates what search condition is specified for which database. Interpreting operation information by the computer with reference to the resource integration information for the integrated resources;
Setting information for making the database usable is transmitted to the database server through the Internet based on an address included in the database access information, and based on operation procedure information included in the database access information, the operation Generating a request representing an operation related to the database represented by information, transmitting the generated request to the database server through the Internet based on an address included in the database access information, and receiving a response to the request by a computer; ,
Setting information for enabling use of the analysis service is transmitted to the analysis service server through the Internet based on an address included in the analysis service access information, and based on operation procedure information included in the analysis service access information Generating a request representing an operation related to the analysis service represented by the operation information, and transmitting the generated request to the analysis service server through the Internet based on an address included in the analysis service access information, Receiving a response by the computer;
And a step of causing the display means to display an operation result for the database or the analysis service on the display unit based on the received response. Realizing an integrated database and analysis service operation system that is connected to one or more database servers and analysis services that respectively provide a database to a computer and that is connected to one or more analysis service servers that provide an analysis service through the Internet. A database and analysis service operation integration program, wherein the database and analysis service operation integration program are stored in the computer,
Storing database access information representing operating procedure information including an address for connecting to each of the database servers via the Internet and interface information and data format for using each of the databases; and
Representing the database on the screen, having an input field for inputting a search condition, and storing a database symbol for accepting an operation for the database in a computer;
Storing in the computer analysis service access information representing operation procedure information including an address for connecting to each of the analysis service servers, and interface information and data format for using each of the analysis services;
Storing, in a computer, resource integration information relating to integrated resources in which a plurality of resources of the database and the analysis service are associated in a predetermined access order and operation order;
Representing the analysis service on a screen and storing an analysis service symbol for accepting an operation for the analysis service in a computer;
Representing the integrated resource on the screen and storing a resource integration symbol in a computer for accepting an operation on the integrated resource;
Causing the computer to display the database symbol, the analysis service symbol, and the resource integration symbol on the screen;
Obtaining an input operation for the database, the analysis service, or the integrated resource, and a search condition for the database, which are input by the user;
The acquired input operation indicates what operation is performed on which database or the analysis service, and the acquired search condition indicates what search condition is specified for which database. Interpreting operation information by the computer with reference to the resource integration information for the integrated resources;
Setting information for making the database usable is transmitted to the database server through the Internet based on an address included in the database access information, and based on operation procedure information included in the database access information, the operation Generating a request representing an operation related to the database represented by information, transmitting the generated request to the database server through the Internet based on an address included in the database access information, and receiving a response to the request by a computer; ,
Setting information for enabling use of the analysis service is transmitted to the analysis service server through the Internet based on an address included in the analysis service access information, and based on operation procedure information included in the analysis service access information Generating a request representing an operation related to the analysis service represented by the operation information, and transmitting the generated request to the analysis service server through the Internet based on an address included in the analysis service access information, Receiving a response by the computer;
An operation integration program for a database and an analysis service, comprising: causing the display unit to display an operation result for the database or the analysis service based on the received response.

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