JP4602005B2 - Antibacterial and deodorant for livestock and poultry - Google Patents
Antibacterial and deodorant for livestock and poultry Download PDFInfo
- Publication number
- JP4602005B2 JP4602005B2 JP2004186939A JP2004186939A JP4602005B2 JP 4602005 B2 JP4602005 B2 JP 4602005B2 JP 2004186939 A JP2004186939 A JP 2004186939A JP 2004186939 A JP2004186939 A JP 2004186939A JP 4602005 B2 JP4602005 B2 JP 4602005B2
- Authority
- JP
- Japan
- Prior art keywords
- antibacterial
- livestock
- poultry
- deodorant
- zeolite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Description
本発明は家畜や家禽類に投与するための抗菌、防臭剤に関するものである。 The present invention relates to an antibacterial and deodorant for administration to livestock and poultry.
家畜、家禽類の飼育を目的とする設備では、家畜、家禽類の健康維持のために、各種抗生物質等を投与している。しかしこうした薬剤が動物の体内に侵入すると抗原が作られ、この抗原と特異的に反応する抗体が発現するため、効力がなくなり、次々と新しい抗生物質を開発してそれに変えなければならない。しかしながら病原菌に対しては抗生物質、ワクチン等の投与というのが社会通念になっており、しかも、例えばサルモネラ菌その他の病原菌から家畜、家禽類を守ることにはこれまで成功していない。 In facilities for raising livestock and poultry, various antibiotics are administered to maintain the health of livestock and poultry. However, when these drugs enter the animal's body, antigens are produced and antibodies that react specifically with the antigens are expressed, so they become ineffective, and new antibiotics must be developed and replaced one after another. However, it is common practice to administer antibiotics and vaccines against pathogenic bacteria, and for example, it has not been successful in protecting livestock and poultry from Salmonella and other pathogenic bacteria.
これに対して本件発明者は、銀及び銅の抗菌性に着目してそれらの有機化合物を還元して活性炭に付着させたものや、その問題点を解決すべく開発した、硝酸銀や硫酸銅を使用した抗菌、防臭剤に関する研究を行って来た。後の発明は２〜１０ｍｍの粒径から成る無機質多孔体を使用し、これを担体として硝酸銀や硫酸銅の水溶液を含浸させ、数百度の温度で焼成したもので、得られた抗菌、防臭剤は、水道水に対する濾過剤であるとか、養魚池の水質改善剤、水耕田の水質改善剤として使用する（特開平５−５８８２９号）。 On the other hand, the present inventors focused on the antibacterial properties of silver and copper, and reduced those organic compounds to adhere to activated carbon, and developed silver nitrate and copper sulfate developed to solve the problems. We have conducted research on the antibacterial and deodorant used. The later invention uses an inorganic porous material having a particle diameter of 2 to 10 mm, impregnates an aqueous solution of silver nitrate or copper sulfate as a carrier, and fires it at a temperature of several hundred degrees. The obtained antibacterial and deodorant Is used as a filtering agent for tap water, as a water quality improving agent for fish ponds, and as a water quality improving agent for hydroponic fields (Japanese Patent Laid-Open No. 5-58829).
しかし同発明及び、それに先行する特開昭６０−１００５０４号、同じく６１−２７９０６号などの抗菌剤類は、細菌が存在している水中に投与して使用する。故に、目的とする家畜、家禽類の体内に既に存在している細菌に対しては効果がない。 However, the present invention and the antibacterial agents such as JP-A-60-100504 and 61-27906 preceding the same are administered and used in water in which bacteria are present. Therefore, it has no effect on the bacteria already existing in the target livestock and poultry.
本件の発明に当たり、発明者は銀ゼオライト及び銅ゼオライトの生体に与える影響について研究した。ゼオライトは極めて安全な物質であり、整腸作用、臭気除去作用があり、家畜について経口投与最大量５ｇ／ｋｇでも死亡例は見られず、皮膚刺激に反応なく、変異原性試験では突然変異誘起性は陰性であるという報告もあった。また摂取後、銀及び銅ともに適時排泄され、事実上無毒性として扱えることも判明した。本発明に係る抗菌、防臭剤１グラムを１リットルの蒸留水に常温にて２４時間浸漬させ、遠心分離後上澄み液について溶存している銀及び銅の濃度を検査したところ、銀、銅ともミリグラム単位で０．０１未満、即ち０．０１ｐｐｍ未満であり、生体に吸収されることなく排泄されることと相俟って、安全性に全く問題のないことを確認することができた。 In the present invention, the inventors studied the influence of silver zeolite and copper zeolite on the living body. Zeolite is an extremely safe substance, has an intestinal regulating action, and an odor removal action. No fatal cases have been observed in domestic animals even at the maximum oral dose of 5 g / kg, and it does not respond to skin irritation. There were also reports that sex was negative. It was also found that after ingestion, both silver and copper are excreted in a timely manner and can be treated as virtually non-toxic. 1 gram of antibacterial and deodorant according to the present invention was immersed in 1 liter of distilled water at room temperature for 24 hours, and the concentration of silver and copper dissolved in the supernatant after centrifugation was examined. The unit was less than 0.01, that is, less than 0.01 ppm, and it was confirmed that there was no problem in safety in combination with being excreted without being absorbed by the living body.
本発明はこのような知見に着目してなされたもので、その課題は、家畜、家禽類の体内に存在する細菌類に対して効果的な殺菌能力を発揮する家畜、家禽用抗菌、防臭剤を提供することである。 The present invention has been made paying attention to such knowledge, and the subject is livestock, livestock, antibacterial for poultry, and deodorant that exert effective disinfecting ability against bacteria present in the body of livestock and poultry. Is to provide.
前記の課題を解決するため本発明は、家畜や家禽類に投与するための抗菌、防臭剤について、銀ゼオライト及び銅ゼオライトの混合物を重量比で全量の４．５〜８．０％含有し、２〜５％の酸化チタンと、３〜５％のカルシウムを含み粒径約１ｍｍ以下のものから成るものとするという手段を講じたものである。 In order to solve the above-mentioned problems, the present invention contains a mixture of silver zeolite and copper zeolite in a weight ratio of 4.5 to 8.0% by weight with respect to antibacterial and deodorant for administration to livestock and poultry, A measure was taken to comprise 2 to 5% titanium oxide and 3 to 5% calcium and a particle size of about 1 mm or less.
本発明に係る抗菌、防臭剤は、家畜や家禽類に投与することを目的とするものであり、投与方法は様々であるが、最終的には家畜や家禽類の体内に導入され、体内に生存している細菌に作用してこれを殺菌の上、体外へ排出させる使用方法を取る。即ち本発明は、銀ゼオライト及び銅ゼオライトを家畜、家禽類の生体内に導入して、細菌を殺菌する方法にも関するものである。 The antibacterial and deodorant according to the present invention is intended to be administered to livestock and poultry, and there are various administration methods, but it is finally introduced into the livestock and poultry, It is used by acting on living bacteria and sterilizing them, and discharging them outside the body. That is, the present invention also relates to a method for sterilizing bacteria by introducing silver zeolite and copper zeolite into living bodies of domestic animals and poultry.
ゼオライトは、調整された多孔質のアルミニウム、カルシウム（或いはナトリウム）のケイ酸塩（例えばＣａＯ・２Ａｌ２Ｏ３・５ＳｉＯ２、Ｎａ２Ｏ・２Ａｌ２Ｏ３・５ＳｉＯ２）水和物であり、これに銀又は銅を固定したものが銀ゼオライト又は銅ゼオライトである。ゼオライトに銀又は銅を固定する方法は従来と同様で良く、自己の先登録例である特開平５−５８８２９号に記載してある方法を利用することができる。具体的には、硝酸銀の０．１〜１％の水溶液を用意し、これとゼオライトを攪拌混合機で混合してゼオライトの無機質多孔体表面に硝酸銀を付着させ、これを４００〜６００℃の温度において焼成することによって、硝酸銀を固定する方法が取られる。銅ゼオライトの場合には、硝酸銀に変えて硝酸銅を使用するが、その水溶液濃度及び混合後の焼成温度等は硝酸銀の場合と同じで良い。 Zeolites, silicates (e.g. CaO · 2Al 2 O 3 · 5SiO 2, Na 2 O · 2Al 2 O 3 · 5SiO 2) of the adjusted porous aluminum, calcium (or sodium) a hydrate, What fixed silver or copper to this is silver zeolite or copper zeolite. The method for fixing silver or copper to zeolite may be the same as the conventional method, and the method described in Japanese Patent Application Laid-Open No. 5-58829, which is an example of self-registration, can be used. Specifically, a 0.1 to 1% aqueous solution of silver nitrate is prepared, and this and zeolite are mixed with a stirring mixer to adhere silver nitrate to the surface of the inorganic porous body of the zeolite. The method of fixing silver nitrate is performed by baking in step. In the case of copper zeolite, copper nitrate is used instead of silver nitrate, but the concentration of the aqueous solution and the firing temperature after mixing may be the same as in the case of silver nitrate.
但し、ゼオライトの粒径は、最大約１ｍｍとする。家畜、家禽の経口投与の妨げとならないようにする必要があり、上記ゼオライトの粒径は最大値であるので、これ以下であれば何ら支障はない。ゼオライトを硝酸銀の０．１〜１％水溶液又は硝酸銅の０．１〜１％の水溶液とゼオライトを攪拌混合機で混合する時間は約２０分間を上限とし、硝酸銀又は硫酸銅の付着しているゼオライトを焼成する温度は４００〜６００℃の範囲とする。混合時間が１０分未満では硝酸銀又は硫酸銅をゼオライトに十分に付着させることができず、３０分を越えても硝酸銀又は硫酸銅のゼオライト付着量の増加は頭打ちとなる。また焼成時間４００℃未満では焼成後、硝酸イオン、硫酸イオンが残存する余地があり、６００℃を越えると、ゼオライトの多孔質部分が溶解などで崩壊して機能を喪失する場合があるからであり、焼成時間はおおよそ１時間ないし２時間前後が良い。 However, the maximum particle size of the zeolite is about 1 mm. It is necessary not to interfere with the oral administration of livestock and poultry, and the particle size of the zeolite is the maximum value. The time for mixing zeolite with 0.1 to 1% aqueous solution of silver nitrate or 0.1 to 1% of copper nitrate and zeolite with a stirring mixer is about 20 minutes, and silver nitrate or copper sulfate is adhered. The temperature at which the zeolite is calcined is in the range of 400 to 600 ° C. If the mixing time is less than 10 minutes, the silver nitrate or copper sulfate cannot be sufficiently adhered to the zeolite, and even if it exceeds 30 minutes, the increase in the amount of silver nitrate or copper sulfate adhering to the zeolite reaches a peak. Also, if the firing time is less than 400 ° C, there is room for nitrate ions and sulfate ions to remain after firing, and if it exceeds 600 ° C, the porous part of the zeolite may collapse due to dissolution and lose its function. The firing time is preferably about 1 to 2 hours.
本発明に係る家畜、家禽用抗菌、防臭剤は、このようにして製造した銀ゼオライト及び銅ゼオライトの混合物を重量比で全量の４．５〜８．０％含有する。銀ゼオライトと銅ゼオライトの混合比率は任意で良い。銀ゼオライト、銅ゼオライトの他には、２〜５％の酸化チタンと３〜５％のカルシウムを含める。酸化チタンは光抗菌のために必要であり、そのための適量が２〜５％の範囲である。またカルシウムは栄養補給のために必要であり、そのための適量が３〜５％の範囲である。 The antibacterial and deodorant for livestock and poultry according to the present invention contain 4.5 to 8.0% of the total amount of the mixture of silver zeolite and copper zeolite thus produced. The mixing ratio of silver zeolite and copper zeolite may be arbitrary. In addition to silver zeolite and copper zeolite, 2-5% titanium oxide and 3-5% calcium are included. Titanium oxide is necessary for photoantibacterial activity, and the appropriate amount thereof is in the range of 2 to 5%. Calcium is necessary for nutritional supplementation, and the appropriate amount is 3 to 5%.
本発明に係る家畜、家禽用抗菌、防臭剤を家畜、家禽類へ供給する方法は、飼料への添加、或いは水への混合、或いは畜舎、禽舎等飼育設備への散布となる。飼料への添加量、及び飲料への混合量は重量比でいずれも０．４〜６％の範囲とするのが望ましい。０．４％未満では抗菌力の不足する場合があり、６％を越えても抗菌効果は向上しないからである。また、畜舎、禽舎など飼育設備への散布は、散布した抗菌、防臭剤の殺菌効果と、舎内に舞い上がるパウダーを吸引させることによって、家畜、家禽類の生体に作用させることも期待される。このように本発明に係る抗菌、防臭剤は経口的に家畜、家禽類に投与され消化器系に作用する、その一方では、呼吸器系において作用する余地もある。 The method for supplying the livestock, poultry antibacterial and deodorizers to the livestock and poultry according to the present invention involves adding to feed, mixing with water, or spraying to breeding facilities such as livestock and poultry houses. The amount added to the feed and the amount mixed into the beverage is preferably in the range of 0.4 to 6% by weight. If it is less than 0.4%, the antibacterial activity may be insufficient, and if it exceeds 6%, the antibacterial effect is not improved. In addition, spraying to breeding facilities such as livestock houses and poultry houses is expected to act on the livestock of livestock and poultry by sucking the antibacterial effect of the sprayed antibacterial and deodorants and the powder that soars in the house. Thus, the antibacterial and deodorant agents according to the present invention are orally administered to livestock and poultry and act on the digestive system, while there is room for acting on the respiratory system.
本発明は以上の如く構成されかつ作用するものであるから、本発明に係る家畜、家禽用抗菌、防臭剤を、飼料や飲料などを通して家畜、家禽類の体内に投与し、体内に生存している細菌類に作用してこれを殺菌することができ、抗菌、防臭剤は消化器系を通って体外に排泄され、生体に対して必要以上に作用し続けることがないので、摂取と排泄を繰り返す間に体内の細菌を死滅させることができ、しかも排泄物中の抗菌、防臭剤は排泄物中の細菌類に対しても殺菌効果を発揮するので、清潔な飼育環境を維持することができる等、顕著な効果を奏する。 Since the present invention is configured and operates as described above, the livestock, poultry antibacterial and deodorant according to the present invention are administered to livestock and poultry through feeds and beverages, and survive in the body. Can be sterilized by acting on bacteria, antibacterial and deodorants are excreted outside the body through the digestive system and do not continue to act on the living body more than necessary. Bacteria in the body can be killed during repetition, and the antibacterial and deodorant in the excrement also exerts a bactericidal effect on the bacteria in the excrement, thus maintaining a clean breeding environment And so on.
以下、本発明に係る家畜、家禽類用の抗菌、防臭剤を実施するための最良の形態について説明する。 Hereinafter, the best mode for carrying out the antibacterial and deodorant for livestock and poultry according to the present invention will be described.
＜銀ゼオライト、銅ゼオライトの製造＞
実施例の場合、平均粒径０．２ｍｍのゼオライトを使用し、０．５％の硝酸銀水溶液とゼオライトを撹拌混合機で約２０分間混合し、脱水、乾燥ののち、加熱炉で４００℃にて１．５時間加熱、焼成し、銀ゼオライトを製造した。同じく、粒径０．２ｍｍのゼオライトを使用し、０．５％の硫酸銅水溶液とゼオライトを撹拌混合機で約１５分間混合し、脱水、乾燥ののち、加熱炉で５００℃にて１．５時間加熱、焼成し、銅ゼオライトを製造した。
<Manufacture of silver zeolite and copper zeolite>
In the case of the examples, zeolite having an average particle diameter of 0.2 mm is used, 0.5% aqueous silver nitrate solution and zeolite are mixed for about 20 minutes with a stirring mixer, dehydrated and dried, and then heated at 400 ° C. in a heating furnace. It was heated and calcined for 1.5 hours to produce silver zeolite. Similarly, a zeolite having a particle size of 0.2 mm is used, and a 0.5% copper sulfate aqueous solution and zeolite are mixed for about 15 minutes with a stirring mixer, dehydrated and dried, and then heated at 500 ° C. in a heating furnace at 1.5 ° C. Copper zeolite was produced by heating and calcining for a period of time.
＜実施例１＞
上記の銀ゼオライトと銅ゼオライトの１：０．１混合物を重量比で７．５％含有し、これに２．５％の酸化チタン、３．５％のカルシウム、残部タルクを混合して、本発明に係る家畜、家禽用抗菌、防臭剤１を製造した。この抗菌、防臭剤１を養鶏飼料に重量比で５％添加し、これを摂取した群と、抗菌、防臭剤１を全く摂取しなかった群に分け、夫々の群の鶏のサルモネラ菌に対する抗菌性を比較したところ、次の結果を得た。
抗菌、防臭剤１を５％添加した群
１）１時間後のサルモネラ生菌数は、初発菌数の４７％であった。
２）３時間後のサルモネラ生菌数は、初発菌数の４％であった。
３）６時間後のサルモネラ生菌数は、初発菌数の３％であった。
抗菌、防臭剤１を使用しなかった群
１）１時間後のサルモネラ生菌数は、補充菌数の８０％であった。
２）３時間後のサルモネラ生菌数は、補充菌数の１８８％であった。
３）６時間後のサルモネラ生菌数は、補充菌数の８２２％であった。
<Example 1>
It contains 7.5% by weight of the above 1: 0.1 mixture of silver zeolite and copper zeolite, mixed with 2.5% titanium oxide, 3.5% calcium and the balance talc. Antibacterial and deodorant 1 for livestock and poultry according to the invention were produced. This antibacterial and deodorant 1 was added to the poultry feed by 5% by weight and divided into a group ingested and a group in which no antibacterial and deodorant 1 was ingested, and the antibacterial properties of each group of chickens against Salmonella The following results were obtained.
Group 1 to which 5% of antibacterial and deodorant 1 was added 1) Salmonella viable count after 1 hour was 47% of the initial bacterial count.
2) The number of viable Salmonella after 3 hours was 4% of the initial number of bacteria.
3) The number of viable Salmonella after 6 hours was 3% of the initial number of bacteria.
Group 1 in which antibacterial and deodorant 1 was not used 1) Salmonella viable count after 1 hour was 80% of the supplemented bacterial count.
2) The number of viable Salmonella after 3 hours was 188% of the number of supplemented bacteria.
3) The number of viable Salmonella after 6 hours was 822% of the number of supplemented bacteria.
＜実施例２＞
前記の銀ゼオライトと銅ゼオライトの１：１混合物を重量比で６．５％含有し、これに３．５％の酸化チタン、４．０％のカルシウム、残部タルクを混合して、本発明に係る家畜、家禽用抗菌、防臭剤２を製造した。この抗菌、防臭剤２を養豚飼料に重量比で２．５％添加し、これを摂取した群と、抗菌、防臭剤２を全く摂取しなかった群に分け、夫々の群の豚の糞便性大腸菌に対する抗菌性を比較したところ、次の結果を得た。
抗菌、防臭剤２を２．５％添加した群
１）１時間後の糞便性大腸菌生菌数は、初発菌数の５０％であった。
２）３時間後の糞便性大腸菌生菌数は、初発菌数の５％であった。
３）６時間後の糞便性大腸菌生菌数は、初発菌数の２％であった。
抗菌、防臭剤２を添加しなかった群
１）１時間後の糞便性大腸菌生菌数は、初発菌数の１２０％であった。
２）３時間後の糞便性大腸菌生菌数は、初発菌数の２５０％であった。
３）６時間後の糞便性大腸菌生菌数は、初発菌数の７５０％であった。
<Example 2>
The present invention contains a 1: 1 mixture of silver zeolite and copper zeolite in a weight ratio of 6.5%, and this is mixed with 3.5% titanium oxide, 4.0% calcium and the balance talc. Such antibacterial and deodorant 2 for livestock and poultry were produced. This antibacterial and deodorant 2 is added to pig feed by 2.5% by weight and divided into a group ingesting this and a group in which no antibacterial and deodorant 2 is ingested. When the antibacterial activity against E. coli was compared, the following results were obtained.
Group 1 to which 2.5% of antibacterial and deodorant 2 was added 1) The number of viable fecal coliforms after 1 hour was 50% of the initial bacterial count.
2) The number of viable fecal Escherichia coli after 3 hours was 5% of the initial bacterial count.
3) The number of viable fecal Escherichia coli after 6 hours was 2% of the initial bacterial count.
Group 1 to which antibacterial and deodorant 2 was not added 1) The number of viable fecal Escherichia coli after 1 hour was 120% of the initial number of bacteria.
2) The number of viable fecal Escherichia coli after 3 hours was 250% of the initial bacterial count.
3) The number of viable fecal Escherichia coli after 6 hours was 750% of the initial bacterial count.
＜実施例３＞
前記銀ゼオライトと銅ゼオライトの２：１混合物を重量比で５．０％含有し、これに５％の酸化チタン、４．５％のカルシウム、残部タルクを混合して、本発明に係る家畜、家禽用抗菌、防臭剤３を製造した。この抗菌、防臭剤３を養牛飼料に重量比で５％添加し、これを摂取した群と、抗菌、防臭剤３を全く摂取しなかった群に分け、夫々の群の牛の糞便性大腸菌に対する抗菌性を比較したところ、次の結果を得た。
抗菌、防臭剤３を５％添加した群
１）１時間後の糞便性大腸菌生菌数は、初発菌数の５５％であった。
２）３時間後の糞便性大腸菌生菌数は、初発菌数の７％であった。
３）６時間後の糞便性大腸菌生菌数は、初発菌数の２％であった。
抗菌、防臭剤３を使用しなかった群
１）１時間後の糞便性大腸菌生菌数は、初発菌数の１２０％であった。
２）３時間後の糞便性大腸菌生菌数は、初発菌数の２５０％であった。
３）６時間後の糞便性大腸菌生菌数は、初発菌数の７５０％であった。
<Example 3>
Containing a 2: 1 mixture of silver zeolite and copper zeolite in a weight ratio of 5.0%, mixed with 5% titanium oxide, 4.5% calcium and the balance talc, Antibacterial and deodorant 3 for poultry was produced. This antibacterial and deodorant 3 is added to the cattle feed by 5% by weight and divided into a group that has been ingested and a group that has not received the antibacterial and deodorant 3 at all. When the antibacterial properties were compared, the following results were obtained.
Group 1 to which 5% of antibacterial and deodorant 3 was added 1) The number of viable fecal Escherichia coli after 1 hour was 55% of the initial bacterial count.
2) The number of viable fecal Escherichia coli after 3 hours was 7% of the initial bacterial count.
3) The number of viable fecal Escherichia coli after 6 hours was 2% of the initial bacterial count.
Group 1 in which antibacterial and deodorant 3 was not used 1) The number of viable fecal coliforms after 1 hour was 120% of the number of the first germs.
2) The number of viable fecal Escherichia coli after 3 hours was 250% of the initial bacterial count.
3) The number of viable fecal Escherichia coli after 6 hours was 750% of the initial bacterial count.
次に、実施例１の抗菌、防臭剤１について、社団法人東京都食品衛生協会に委託して行った抗菌性（サルモネラ・シェークフラスコ法）試験の結果を示す。
試験方法
１）供試菌液の調整方法
サルモネラ（Ｓａｌｍｏｎｅｌｌａ ｅｎｔｅｒｉｔｉｄｉｓ ＩＰＯ ３３１３）を、普通ブイヨン培地を用いて３５℃において１８時間培養し、供試菌液とした。
２）試験用細菌浮遊液の調整方法
５００分の１濃度普通ブイヨン培地に、滅菌リン酸緩衝生理食塩水で希釈した上記１）の供試菌液を均一に分散させ、試験用細菌浮遊液とした。
３）検体の調整方法
試験品３ｇを１００ｍｌ容三角フラスコに採取し、１２１℃で１５分間高圧滅菌したものを検体とした。
４）試験操作の方法
上記３）の三角フラスコに、上記２）の試験用細菌浮遊液３０ｍｌを加え、３５℃において振とう処理（１２０ｒ．ｐ．ｍ．）し、指定時間ごとにサルモネラの生菌数を測定した。
５）生菌数の測定方法
寒天培地を用い、３５℃において２４時間培養後に形成された集落数を測定した。
試験結果 （ＣＦＵ/ｍｌ）
Test method 1) Preparation method of test bacterial solution Salmonella (Salmonella enteritidis IPO 3313) was cultured at 35 ° C. for 18 hours in a normal broth medium to obtain a test bacterial solution.
2) Preparation of test bacterial suspension The test bacterial suspension of 1) above, diluted with sterile phosphate buffered saline, is uniformly dispersed in a 1/500 concentration normal bouillon medium. did.
3) Preparation method of specimen 3 g of the test product was collected in a 100 ml Erlenmeyer flask and autoclaved at 121 ° C for 15 minutes to prepare a specimen.
4) Method of test operation To the Erlenmeyer flask of 3) above, add 30 ml of the test bacterial suspension of 2) above and shake at 35 ° C. (120 rpm), The number of bacteria was measured.
5) Method for measuring the number of viable bacteria Using an agar medium, the number of colonies formed after culturing at 35 ° C for 24 hours was measured.
Test result (CFU / ml)
このように本発明に係る家畜、家禽類のための抗菌、防臭剤は、飼料への添加、飲料への混合等による生体内への摂取を可能とし、１日に何回かの摂取と排泄を繰り返す間に、サルモネラ菌や大腸菌等を死滅させることとなり、排泄された糞には消臭性、抗菌性があるので安全であり、しかもワクチン、構成物質と異なり耐性菌を作らないので安心して続けることができ、また使用上、製造上有害物質が発生することもない。 As described above, the antibacterial and deodorizing agents for livestock and poultry according to the present invention can be taken into the living body by adding to feed, mixing with beverages, etc., and ingesting and excreting several times a day During this process, Salmonella and Escherichia coli, etc. will be killed, and excreted feces are safe because they have deodorant and antibacterial properties. In addition, no harmful substances are produced during production.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004186939A JP4602005B2 (en) | 2004-06-24 | 2004-06-24 | Antibacterial and deodorant for livestock and poultry |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004186939A JP4602005B2 (en) | 2004-06-24 | 2004-06-24 | Antibacterial and deodorant for livestock and poultry |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006006172A JP2006006172A (en) | 2006-01-12 |
| JP4602005B2 true JP4602005B2 (en) | 2010-12-22 |
Family
ID=35774085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004186939A Expired - Fee Related JP4602005B2 (en) | 2004-06-24 | 2004-06-24 | Antibacterial and deodorant for livestock and poultry |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4602005B2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100835885B1 (en) | 2006-07-04 | 2008-06-09 | 주식회사 에스에프 | Health functional eggs to increase high density cholesterol content |
| KR100890245B1 (en) | 2007-11-23 | 2009-03-24 | (주)하이드로 비티 | Drinking water composition for poultry and preparation method thereof |
| CN113016943A (en) * | 2021-04-01 | 2021-06-25 | 联科华技术有限公司 | Monoatomic feed additive for replacing antibiotics and preparation method thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2567719B2 (en) * | 1990-05-14 | 1996-12-25 | 日本化学工業株式会社 | Antibacterial zeolite |
| JP3422762B2 (en) * | 1992-05-08 | 2003-06-30 | 松下電器産業株式会社 | Odor control pet food |
| JP3159772B2 (en) * | 1992-05-08 | 2001-04-23 | 松下電器産業株式会社 | Antibacterial wax |
| JPH11196831A (en) * | 1998-01-14 | 1999-07-27 | Kenji Nakamura | Agent for modification of material, and modification of material |
-
2004
- 2004-06-24 JP JP2004186939A patent/JP4602005B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006006172A (en) | 2006-01-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10781118B2 (en) | Recirculating, purifying, disinfecting, cooling, decontaminating feedback controlled water system for drinking water and other uses to improve health and well being of animals and humans | |
| US20090283050A1 (en) | Feed composition and method for breeding animals | |
| US20170251674A1 (en) | Application of porous materials for bacterial quorum sensing inhibition/disruption | |
| US20070110822A1 (en) | Use of an aqueous solution in the treatment of live animals | |
| JP2004504823A (en) | Livestock feed composition for antibiotic replacement | |
| CN101237876B (en) | Bacterial management in animal holding systems | |
| JP4602005B2 (en) | Antibacterial and deodorant for livestock and poultry | |
| CN104054753A (en) | Antibacterial and sterilization disinfectant for killing avian influenza viruses | |
| KR100772054B1 (en) | Avian Influenza Disinfection Composition | |
| CN111869680B (en) | Nano dry powder for disinfecting and self-cleaning floor of livestock and poultry house and application method thereof | |
| CN104224824A (en) | Iodine disinfection solution for preventing and treating freshwater biological virus erosion | |
| WO2017173393A1 (en) | Clay-based materials for animal feeding and care | |
| EP4658237A1 (en) | Use of oxidative precursors in poultry farming | |
| CN116139178A (en) | A kind of animal dry powder with disinfection function and preparation method thereof | |
| CN101161070A (en) | Double chain quaternary ammonium salt complex phthalic two methylene oxide disinfectant | |
| JP2000143521A (en) | Animal biomaterials and feed and plant chemicals | |
| CN100361584C (en) | Broad-spectrum antiseptics and production thereof | |
| IE20160180A1 (en) | A composition and a method for controlling bacterial infection | |
| Karomy et al. | Effect of the frequency of the microsafe spraying on the production performance and the microbial presence in mouth and vent of broiler chickens | |
| JPH06303920A (en) | Microbicidal grit for chicken raising | |
| Ymas et al. | Detection of veterinary antibiotic residues in fresh fecal samples collected from selected pig farms in the City of Baybay, Leyte, Philippines | |
| WO2014033490A1 (en) | Preventive products against pathogenic germs, and method for use thereof | |
| JP2004049202A (en) | Feeding of drinking water disinfected by chlorine dioxide and chlorine dioxide agent to cattle | |
| JP2000060442A (en) | Raw material for feed for domestic animal and formulated feed | |
| JP5888872B2 (en) | High concentration metal ion water production |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070319 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100309 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100428 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100907 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20100929 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20131008 Year of fee payment: 3 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20131008 Year of fee payment: 3 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20131008 Year of fee payment: 3 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |