JP4705403B2 - Underwear - Google Patents

Description

The present invention relates to an undergarment in which microcapsule fine particles exhibiting a moisturizing and skin-beautifying effect are fixed to a surface of the underwear that contacts the skin so as to have washing resistance.
In addition, the present invention provides a skin resident bacteria present in the skin by the exuding component of the microcapsule fine particles fixed to the skin contact surface of the underwear, which is contained so that sugar alcohol and organic acid are exuded. It is related with the underwear which improves the moisture retention and the beautiful skin effect of skin so that it may raise selectively.
More specifically, the present invention is based on the exudation component of the fine particles fixed to the underwear, keeping the skin surface at pH 4.5 to 6.0, supplying sugar alcohol to the skin, In particular, the present invention relates to an undergarment that is selectively cultivated with Staphylococcus epidermidis and has improved skin moisturizing and beautifying effects.

  Conventionally, underwear with skin care effects by attaching skin care agents such as vitamin C, vitamin E, seaweed extract, etc. to textile products has been announced, but there are problems with the stability and washing resistance of functional ingredients. As measures for improving the problem, a fiber material having a slimming effect by inclusion of a functional component in cyclodextrin (Japanese Patent Laid-Open No. 2004-027372), and a skin care garment in which squalane is included in cyclodextrin (Japanese Patent Laid-Open No. 06-322670) Although the stability of fixation is improved by inclusion of cyclodextrin, the washing resistance against repeated washing is not improved. It is also known that ascorbic acids and tocopherols are contained in microcapsules mainly composed of formalin-based resin and adhere to undergarments (Japanese Patent No. 2562233). However, microcapsules are components that are permeable to cells. Otherwise, there is a defect that the contents components do not function unless the cell is destroyed, and there is a problem in practical use. Further, there is a technique (Japanese Patent Application Laid-Open No. 2004-308063) for fixing an active ingredient to an undergarment as a sanitary processed undergarment, but there is a conventional defect as well.

  Development of an external preparation for skin that selectively grows and antibacterials skin resident bacteria using sugar alcohol is also known. For example, according to Japanese Patent Laid-Open No. 2000-302674, a combination of farnesol and xylitol is effective as an antibacterial agent used as a skin external agent for the treatment and prevention of skin diseases because it has a selective antibacterial effect on skin resident bacteria. In JP 2000-302673 A, a topical skin preparation formulated with farnesol and / or xylitol is effective in treating atopic dermatitis by selectively exerting an antibacterial effect on skin resident bacteria. ing. Furthermore, in Japanese Patent Application Laid-Open No. 2002-302404, since bacteria are covered with secretions to form a biofilm, this biofilm serves as a barrier and the antibacterial agent is difficult to act. Since the sugar alcohol reduces or eliminates biofilms, it is effective as an antibacterial aid for obtaining an antibacterial effect, but the above-described problems cannot be solved.

JP 2004-027372 A Japanese Patent Laid-Open No. 06-322670 Japanese Patent No. 2562233 JP 2004-308063 A JP 2000-302694 A JP 2000-302673 A JP 2002-302404 A

Originally, the skin is a mechanism that can naturally maintain the skin's moisturizing and skin-beautifying effects by the action of components secreted by the presence of skin resident bacteria. However, for example, when the skin is cooled by exposure of the skin or exposed to ultraviolet rays, beneficial skin resident bacteria are reduced, and dry skin, rough skin, atopic skin, and the like are easily caused.
Therefore, in the present invention, based on the idea opposite to the conventional idea of utilizing antibacterial action, attention was paid to a method of growing good bacteria and utilizing it for beauty. In other words, as an idea to selectively cultivate skin resident bacteria and utilize it for skin beauty, sugar alcohol is used to antibacterial Staphylococcus aureus harmful to the skin resident bacteria (so-called bad bacteria) and at the same time, Staphylococcus epidermidis (So-called good bacteria) was selectively grown. Specifically, by cultivating good bacteria, proteolytic enzymes secreted from the good bacteria are abundant in the skin, and stratum corneum peeling is activated, and the skin is renewed (1) Moisturizing and skin-beautifying effects Can be improved.
“Stratum corneum exfoliation” means that a peptide called “desmosome” that adheres corneocytes to each other is decomposed with an enzyme to exfoliate the stratum corneum, so that it becomes so-called “smudge” and falls off the skin. Degradation produces (2) an amino acid, and this amino acid functions as a natural moisturizing factor to exert moisturizing and beautifying skin effects.

Therefore, in the present invention, as described above, to selectively grow only good bacteria such as Staphylococcus epidermidis among the resident bacteria present in the skin, to eliminate harmful pathogenic bad bacteria, It is an object of the present invention to supply sugar alcohol in an environment of pH 4.5 to 6.0, and further repeat the supply of the sugar alcohol and the acid component to realize underwear having excellent washability.
To solve this problem, sugar alcohol itself is water-soluble, and it is difficult to obtain a durable effect of washing resistance by inclusion with cyclodextrin. It is necessary to create microcapsules, and it is possible to provide underwear that becomes beautiful skin without wearing the wearer's consciousness by wearing underwear, by realizing it as an underwear with washing resistance that has a fungicidal and antibacterial effect It has become possible.

This invention solves the said subject by having the following structures, and is as follows. The underwear according to claim 1 is an underwear having microcapsule fine particles of a polyacrylic resin or polyurethane resin containing an exuding component, and the exuding component is composed of an oil component containing a sugar alcohol and an organic acid. The exuding component is used to cultivate Staphylococcus epidermidis while maintaining the pH of the skin surface in contact with the underwear at 4.5 to 6.0 and to exude the exudation component even after washing the underwear repeatedly. .
The underwear according to claim 2 is characterized in that the fine particles have a diameter of more than 3 μm and less than 10 μm.
The underwear according to claim 3 is characterized in that the sugar alcohol is one or more selected from oligosaccharides, xylitol or farnesol.
The underwear according to claim 4 is characterized in that the oil component is one or more components selected from olive oil, jojoba oil, squalane, squalene, liquid paraffin, paraffin, or wax.
The underwear according to claim 5 is characterized in that the underwear is underwear, underwear, bottom, trousers, nightclothes, socks, socks, pantyhose, T-shirt, lingerie, blouse, bra or sportswear.

  The microcapsules containing the sugar alcohol and organic acid according to the present invention can be obtained by suspension polymerization of a synthetic resin monomer or prepolymer with oil-in-water droplets. A particle size of 10 μm or more is not preferable because the dyeing of underwear changes to pastel. Preferably it is 8 μm or less. If it is 3 μm or less, it is difficult to produce the microcapsule particles. As the synthetic resin component, a polyacrylic or polyurethane monomer or prepolymer is microparticulated by suspension polymerization using oil-in-water droplets. Specifically, Patent No. 3610301 according to the application of the present inventor can be improved to obtain exudable microcapsule fine particles containing a water-soluble sugar alcohol and an organic acid. That is, in Patent No. 3610301, for the production of exudable microcapsule fine particles by suspension polymerization, if the component is difficult to exude, blending one selected from low molecular weight polyethylene, paraffin, triglyceride as an exudation aid, When the component is excessively exuded, it is a technique of blending silica powder or the like impregnated with the component as an exudation inhibitor, but in the present invention, the active component to be contained is a water-soluble sugar alcohol, In the emulsification / suspension polymerization process, the active ingredient is eluted into the aqueous system and emulsification is difficult. Emulsified by maintaining the temperature at a high temperature during emulsification, and emulsifying the emulsified components at a low temperature during suspension polymerization to prevent elution. Improved.

  Moreover, the sugar alcohol in this invention can use 1 type (s) or 2 or more types selected from oligosaccharide, xylitol, or farnesol. As the organic acid, one selected from citric acid, malic acid or tartaric acid is used. In order to blend sugar alcohol and organic acid into the oily component of the oil-in-water droplet, an oily component selected from olive oil, jojoba oil, squalane, squalene, liquid paraffin or paraffin is used as a carrier.

  The present invention is characterized in that the microcapsule fine particles contain 5 to 50% by weight of a component containing the sugar alcohol and organic acid. It is difficult to obtain fine microcapsules of 10 μm or less containing 50% by weight or more by oil-in-water polymerization. If it is contained in an amount of 5% by weight or less, there are few exudation components, which is not preferable. There are dipping methods, coating methods, spraying methods, and printing methods for imparting the fine particles to the underwear, but these methods are not limited to these methods. Although it may be given to the entire surface of the underwear, it may be given partially like a heel part of a sock. As an oily component containing a sugar alcohol and an organic acid, squalane is preferable because it does not feel oily and feels good, but in order to improve the exudability of microcapsule fine particles, liquid paraffin, paraffin, and wax are further added to increase the temperature. It is effective to emulsify and cool and then suspension polymerization.

In order to fix the microcapsule fine particles to the underwear, the microcapsule fine particles are blended in a binder liquid such as polyurethane, epoxy, or acrylic, immersed in a treatment liquid, and fixed by drawing or drying. In addition, there are a coating method, a spraying method, and a printing method, and the fixing method is not specified. Although it may adhere to the entire surface of the underwear, it may partially adhere like the heel of the socks.
Examples of the undergarments to be treated according to the present invention include underwear, underwear, bottom, trousers, nightclothes, socks, socks, pantyhose, T-shirt, lingerie, blouse, bra, or sportswear. Is mentioned.

When the underwear obtained in the present invention is worn, as a result of selectively growing Staphylococcus epidermidis by the exuding component of the microcapsule, the proteolytic enzyme secreted by the fungus is abundant, and exfoliation is promoted by the enzyme. An excellent moisturizing and beautifying effect can be obtained by renewing the skin. In addition, the sugar alcohol and organic acid present on the surface of the microcapsule fine particles are washed away by washing, and the sugar alcohol and organic acid exude to the surface of the underwear after repeated washing of the underwear, and this washing is performed. Even if it is repeated 30 times (after 116 days), this exudation effect does not fade.

  By the underwear of the present invention, the selective growth of the skin resident bacteria can be achieved by keeping the pH of the skin surface in contact with the component from the microcapsule adhering to the underwear at 4.5 to 6.0 and leaching into the sugar alcohol. It is to provide an environment suitable for the growth of Staphylococcus epidermidis. This environment is an antibacterial environment against the Staphylococcus aureus. A pH of 6 or more is not preferable because it is suitable for growing bad bacteria.

In the present invention, the mechanism that brings about the moisturizing and beautifying effects of the skin by wearing the underwear obtained in the present invention is considered as follows.
In other words, when wearing underwear, the selective growth of Staphylococcus epidermidis by the exudate component of microcapsules fixed to the underwear, resulting in an abundance of proteolytic enzymes secreted by the bacteria, which promotes exfoliation Thus, moisturizing and beautifying effects can be obtained by renewing the skin. Exfoliation is due to the degradation of filaggrin peptide that adheres keratinocytes to each other. Amino acids are produced by this degradation, and this amino acid functions as a natural moisturizing factor to obtain moisture and moisturize. A beautiful skin effect is obtained.

  In the present invention, sugar alcohol is allowed to function for the growth of good bacteria, the bad bacteria are made to function as antibacterial, and the increase in the secretion of good bacteria provides natural skin moisturizing and skin beautifying effects. . The exuding component on the surface of the microcapsule is temporarily removed by washing the underwear, but after 2-3 days, the component exudes, so the surface of the microparticles is temporarily washed against repeated washing. However, the effect continues due to the exudation effect. Such an effect cannot be obtained with a general microcapsule.

  Below, the underwear of this invention is demonstrated concretely based on an Example.

[Examples 1 to 5]
(A) Methyl methacrylate / (B) Ethylene glycol dimethacrylate / (C) Squalane / (D) Wax / (E) Sugar alcohol / (F) Citric acid = (A) 50 / (B) 6 / (C While stirring 300g of polymer mixture consisting of 25 / (D) 5 / (E) A / (F) 1, part by weight into 600g of 2.0% aqueous solution of Kuraray Co., Ltd. Poval 220 at 250rpm as suspension stabilizer solution ABN-V 0.6 g of Nippon Hydrazine Co., Ltd. was added as an azo compound initiator as a polymerization initiator, and the mixture was stirred at 30 ° C. for 10 minutes and then reacted at 55 ° C. for 2 hours. .
The reaction was performed in nitrogen gas. Thereafter, 5 g of sodium hypochlorite was added and stirred for 30 minutes to decompose Poval 220 and cooled to room temperature. Next, the reaction product was solid-liquid separated, washed thoroughly with water, and then dried at 70 ° C. for 12 hours. Table 1 shows the formulation A of sugar alcohol to polyacrylic acid resin particles having an average particle size of 7 μm. Such exudable microcapsules were obtained.

[Examples 6 to 10]
(A) Isocyanate prepolymer / (B) Squalene / (C) Paraffin / (D) Sugar alcohol / (E) Citric acid = (A) 60 / (B) 20 / (C) 5 / (D) B / ( E) 300 g of a mixture consisting of 1 part by weight was added as a suspension stabilizer solution to 600 g of a 2.0% aqueous solution of Kuraray Co., Ltd. Poval 220 at 30 ° C. with stirring at 350 rpm, and reacted at 60 ° C. for 2 hours. Thereafter, 5 g of sodium hypochlorite was added and stirred for 30 minutes to decompose Poval 220, and toluene was distilled at 100 ° C. Next, the reaction product was separated into solid and liquid, thoroughly washed with water, and then dried at 70 ° C. for 12 hours. The polyurethane resin particles having an average particle size of 6 μm were blended with sugar alcohol B as shown in Table 2. Sex microcapsules were obtained.

  100 g of microcapsules according to the example were added to 1 L of Superflex E-2000 (Daiichi Kogyo Seiyaku Co., Ltd. product, polyurethane adhesive, 50% solids emulsion) diluted to 10% solids by adding water. Mix and stir. A skin knitted cotton knitted fabric was dipped in the mixture and squeezed with a mangle, and a liquid application rate of 90% by weight with respect to the base fabric weight was applied, followed by drying at 95 ° C. for 30 minutes. The processed underwear fabric was washed for 30 minutes at 40 ° C. with Method B Synthetic Detergent 1 according to JISL0844, a dyeing fastness test for washing, and dried.

The polyacrylic microcapsules, by fixing the cotton knitted as in Example by polyurethane adhesive, by measuring the absorbance 3360.1110.1090.1063.1010. Cm ^-1 xylitol by infrared analyzer, exudative and laundering The properties are shown in Tables 3 and 4. Tables 3 and 4 show the results of confirming xylitol by the infrared analyzer before and after washing for the first, fifth and tenth times. Laundry was measured and left for 3 days, and then washed on the 4th day. The measurement of xylitol was performed before and after the washing, so the 5th wash from the first wash is 4 days. × 4 = It was done on the 16th day, and the 10th washing was done on the 4th × 9 = 36th day. The 30th wash requires 116 days.

  As shown in Tables 3 and 4, the presence of sugar alcohol was confirmed before washing, but was not confirmed after washing. This means that the sugar alcohol present on the surface of the fine particles is washed away by washing, but exudes to the surface of the underwear after being left for 3 days. This also indicates that the sugar alcohol on the underwear surface is washed away by washing, but even if this washing is repeated 30 times (after 116 days), this exudation effect does not fade.

Using as a sample a skin-wearing cotton knitted fabric (fabric whose processing conditions are described in [0019]) treated with fine particles according to the formulations of Examples 1 to 10, 1 × 10 ⁶ epidermis staphylococci / cc, 1 × 10 S. aureus The same amount of ⁶ / cc was mixed and the number of bacteria was measured according to the antibacterial test method of JIS1902 textiles. Table 5 shows the change in the number of bacteria after 12 hours of culture.

In all of Examples 1 to 10, (1) Staphylococcus epidermidis (good bacteria) is remarkably increased from 10 ⁶ to 10 ¹¹ to ¹³ and retains its effect even after repeated washing. (2) Staphylococcus aureus (bad bacteria) has been reduced from 10 ⁶ to 10 ² to ³ and an antibacterial effect appears. At the 10 ² level, bacteria are said to hardly function.
The present invention is expected as a technology that responds to the strong needs of society seeking safety and hygiene for cosmetics used directly on the skin. In the comparative example, conversely, (1) Staphylococcus epidermidis (good bacteria) is reduced, and (2) Staphylococcus aureus (bad bacteria) is increased. This is a sanitary problem.

[Confirmation of bactericidal and moisturizing effects]
In the examples according to the present invention, Staphylococcus epidermidis is significantly grown and Staphylococcus aureus is reduced, whereas in the comparative example, Staphylococcus epidermidis is conversely reduced and Staphylococcus aureus is significantly increased.
Wear the cotton underwear processed in Example 5 for 1 day, wash it, leave it for 3 days, keep the exudation period, wear it again after 4 days, wear 4 underwear one after another and wear for 1 month As a result of continuing the test on 20 people, 18 people, corresponding to 90%, were noticeably moisturized. Ten people with dry skin were all moisturized. The skin beautifying effect due to stratum corneum peeling was observed in 16% of 80%. As described above, it was confirmed that the wearing of the underwear has the effect of moisturizing the skin and having a beautiful skin. All six people who had itchy skin no longer feel itchy.
As described above, as shown in Table 5, the majority of the people whose skin was markedly moistened by wearing the undergarments obtained by the steps of the examples were particularly moisturizing for all dry skin. I was able to confirm. Moreover, the skin-beautifying effect by stratum corneum peeling was also recognized. Moreover, even for those who had itchy skin, there was an effect of not feeling itching.

Claims (5)

Underwear having microcapsule fine particles of polyacrylic resin or polyurethane resin containing an exudation component ,
The exudate component is composed of an oily component blended with sugar alcohol and an organic acid, and the exudate component is used to grow staphylococcus epidermidis while maintaining the pH of the skin surface in contact with the underwear at 4.5 to 6.0, and the above underwear is repeated. An underwear characterized in that the exuding component is exuded even after washing . The underwear according to claim 1, wherein the fine particles have a diameter of more than 3 µm and less than 10 µm . The undergarment according to claim 1 or 2 , wherein the sugar alcohol is one or more selected from oligosaccharides, xylitol or farnesol. The oil component is, olive oil, jojoba oil, squalane, squalene, according to any one of claims 1 to 3, wherein the liquid paraffin, paraffin, or one or more components selected from waxes Underwear. The underwear is underwear, underwear, bottom, trousers, nightclothes, socks, socks, pantyhose, T-shirt, lingerie, blouse, bra, or sportswear, according to any one of claims 1 to 4. Underwear.