JP4860441B2 - Light irradiation apparatus and program - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a light irradiating apparatus for alleviating a sleep disorder or feeling of fatigue such as a jet lag syndrome efficiently in a short time, a program, and a light irradiating method. <P>SOLUTION: The light irradiating apparatus comprises an illuminating device 13 emitting light of a prescribed wavelength, a time difference obtaining part 1 for obtaining a time difference from a place of departure to a destination, and an irradiation period of time determining part 2 for determining a period of time for irradiating with the irradiating light from the time difference, and further comprises an irradiation time determining part 4 for determining the time for irradiating with the irradiating light from the time difference, and an irradiation control part 5 for controlling the irradiation of the light of the prescribed wavelength coming out of the illuminating device 13 from the determined irradiating period of time and the irradiating time. <P>COPYRIGHT: (C)2008,JPO&amp;INPIT

Description

The present invention relates to a light irradiation apparatus and program , and more particularly to a light irradiation apparatus and program for reducing jet lag.

  A person has a biological rhythm (circucdian rhythm) of a cycle of about one day, and thereby, awakening during the day and sleep at night are repeated. This biological rhythm is actually slightly longer than 24 hours, but the biological rhythm is adapted to the actual living environment by advancing the phase of the biological rhythm cycle by exposure to light in the morning. That is, light is important for the adjustment of biological rhythm.

  It is also known that light affects the secretion of a sleep-related hormone called melatonin. Melatonin is a hormone that is generally secreted from the pineal gland of the brain from the time before sleep at night to the first half of sleep. It is believed that the secretion of melatonin promotes a decrease in body temperature and promotion of falling asleep, but it is known that the secretion is suppressed by exposure to relatively strong light at night and affects subsequent sleep. On the other hand, it is also known that the amount of melatonin secretion at night increases when exposed to relatively strong light during the day.

As described above, light has a great relationship with adjustment of biological rhythms and suppression of melatonin secretion, and is important for humans in the time of light irradiation, the energy (intensity) of light, and the time of light irradiation. It has been said.
Therefore, when a person moves to a place where a time difference occurs using a moving means such as an aircraft, the biological rhythm that has adapted to the light environment of the departure place is the daytime / nighttime light / dark environment of the destination. It is impossible to adjust to the cycle immediately, and symptoms such as sleep disturbance and fatigue appear.
This is generally called jet lag (time difference blur), and is known as a problem that plagues long-distance travellers.
In addition, shift workers who cannot get up and go to sleep at regular times, rhythm disabled persons, and the like, are unable to adapt their biological rhythm to the light environment, and thus suffer from the same symptoms as jet lag.

As a technique for solving the above-mentioned symptoms, a light irradiation device described in Patent Document 1 is known. This light irradiation device utilizes the fact that irradiation of high illuminance light from morning to past noon is effective for adjustment of biological rhythm. Illumination light is emitted, and illumination light with a low light emission level is emitted during the calming period.
However, recently, it has become clear that the influence of light on the secretion of melatonin varies depending on the wavelength (Non-patent Document 1). In this Non-Patent Document 1, investigation is made on the influence of single wavelength light having a wavelength of 440 [nm] to 600 [nm] on the secretion of melatonin, and in particular, single wavelength light in the vicinity of a wavelength of 470 [nm] is melatonin. It has been reported to suppress secretion.

  FIG. 15 is a graph showing the relationship between the wavelength of light and the magnitude of the effect on melatonin secretion, where the horizontal axis represents the wavelength of light [nm] and the vertical axis represents the degree of influence on melatonin secretion ( Non-patent document 1). In FIG. 15, light having a wavelength of 464 [nm] most suppresses the secretion of melatonin, and the degree of influence thereof is 1. The degree of influence on light having a wavelength other than 464 [nm] is shown as a relative value for the degree of influence (= 1) on light having a wavelength of 464 [nm]. That is, even with light having the same amount of luminescence, the magnitude of the influence on the secretion of melatonin varies depending on the spectral distribution, and light containing a large amount of energy in the wavelength region near the wavelength 464 [nm] is effective in suppressing the secretion of melatonin. Is big.

FIG. 16 is a graph showing the relationship between the time period during which light is irradiated and the magnitude of the forward or backward effect of the phase of the biological rhythm (see Non-Patent Document 2). In FIG. 16, the horizontal axis of the graph indicates the time when the minimum body temperature appearance time of the person is 0, and the vertical axis indicates the number of times the phase of the biological rhythm moves forward or backward as a positive value and a negative value, respectively. ing. For example, if light is irradiated 4 hours after the lowest body temperature appearance time, the phase of the biological rhythm advances about 2 hours, and if light irradiation is performed 3 hours before the lowest body temperature appearance time, the phase of the biological rhythm is about Retreat for 3 hours.
In addition, irradiation of light from about 1 hour to about 10 hours after the lowest body temperature appearance time advances the phase of the biological rhythm, and conversely, about 12 hours before the lowest body temperature appearance time and about 1 of the lowest body temperature appearance time. Light irradiation until after the time reverses the phase of the biological rhythm.

  As a technique for adjusting the biological rhythm using the above research results, a light irradiation device described in Patent Document 2 is known. In the light irradiation device described in Patent Document 2, in the time zone from the lowest body temperature appearance time of the biological rhythm to at least 11 hours later, it contains a lot of energy in the wavelength range of 410 [nm] to 505 [nm], In addition, light irradiation is performed by a light source with less energy included in a wavelength range of 510 [nm] to 610 [nm]. In other time periods, the biological rhythm is adjusted by illuminating with a general white light source.

In the light irradiation device described in Patent Document 1, the biological rhythm of a person is divided into a calming period and an activation period, illumination with a low light emission level is irradiated in the calming period, and a high light emission level is activated in the activation period. In addition, illumination including low color temperature light is irradiated during the calming period, and illumination including a lot of high color temperature light is activated during the activation period.
When using this light irradiation device to mitigate jet lag that occurs when traveling to a country with a time difference, the jet lag can be adjusted by gradually matching the lifestyle pattern before travel to the daytime and night fluctuations of the outside world at the destination. It has been resolved. For example, when traveling to a country with a jet lag of about 12 hours, the calming period of the destination is the activation period of the departure place, and the day and night are almost reversed. Light irradiation is performed in accordance with the external environment of the ground, and the illumination turn-off time is gradually shifted from the next cycle, and finally irradiation light that is synchronized with the daytime and nighttime fluctuations of the external environment at the destination is irradiated.

On the other hand, in the light irradiation apparatus described in Patent Document 2, a biological rhythm is predicted by using a general minimum body temperature appearance time of a person, and the light irradiation time is determined. The maximum peak is in the wavelength range of 410 [nm] to 505 [nm], with the recommended period of time from at least 11 hours after the lowest body temperature appearance time and from about 15:00 in the morning to the normal business start time. In addition, light irradiation is performed by a light source having a large amount of energy included in the wavelength region. Further, from the end time of the recommended irradiation time zone to the start time of the next recommended irradiation time zone from at least about 5 hours later, the irradiation stop time zone is set, and light irradiation is prohibited. In other words, in the time zone from sunset time to the time before sunrise, light irradiation is prohibited to prevent suppression of melatonin secretion, and in the time zone from about sunrise time to 15:00, Irradiation is performed to improve the melatonin secretion effect at night.
JP 2000-294388 A JP 2005-310654 A "Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor", Brainerd et al, 2001 "A Phase Response Curve to Single Bright Light Pulses in Human Subjects", Sat Bir S. Kha006Csa et al, 2003

  However, the light irradiation device described in Patent Document 1 has a problem that it takes 1 day per hour difference to eliminate the jet lag. If the cycle is shifted by 1 hour, it takes 12 days to eliminate the 12-hour time difference, which is inefficient, and the light source is used at the departure point to adapt to the destination environment. In the meantime, there is also a problem that the life at the departure point is disturbed.

  Moreover, in the light irradiation apparatus described in patent document 2, in order to adjust to an appropriate biological rhythm in the light environment where the user lives, the recommended irradiation time zone and the minimum body temperature appearance time of the user are used. The irradiation stop time zone is determined. Therefore, for example, immediately after the user moves to a place where a time difference occurs, the biological rhythm of the user adapts to the light environment in the place before the movement. For this reason, there is a problem that the jet lag cannot be eliminated even if the lowest body temperature appearance time of the user in such a state is used.

This invention is made | formed in view of the said situation, The objective is to provide the light irradiation apparatus and program which can reduce sleep disorders, such as a jet lag, and a feeling of fatigue efficiently in a short time. . Although it is conceivable to eliminate the jet lag by continuously irradiating light of a predetermined wavelength, the following method can bring about a very large effect on the jet lag.

(1) A light irradiation apparatus according to a first aspect of the present invention includes a light source unit that irradiates light of a predetermined wavelength, a time difference acquisition unit that acquires a time difference from a starting point to a destination, the time difference , and biological rhythm an irradiation time period determination unit which determines the irradiation time period of the illumination light based on the maximum time of the phase shift in the phase response curve, and the irradiation time determining unit that determines the irradiation time of the irradiation light on the basis of the time difference, before An irradiation control unit that controls the irradiation of the light of the predetermined wavelength from the light source unit , the irradiation control unit based on the time difference and the maximum time of phase shift in the phase response curve The number of times of irradiation is determined, and the light source unit is irradiated with light of the predetermined wavelength for the number of times of irradiation.

(2) In the light irradiation apparatus according to the first aspect of the present invention, the light source unit irradiates light having a large energy in a wavelength region near 464 [nm] as the light having the predetermined wavelength. May be.

(3) Moreover, in the light irradiation apparatus according to the first aspect of the present invention, the irradiation control unit sets the irradiation time and a predetermined light energy value in the irradiation time zone determined by the light irradiation time zone determination unit. Based on this, the irradiation of light from the light source unit may be controlled.

(4) The light irradiation device according to the first aspect of the present invention further includes a phase response curve storage unit that stores a phase response curve of a biological rhythm, and the maximum time of deviation due to phase advance in the phase response curve. When the A time and the maximum time of deviation due to the phase retreat are set as B time and the time difference from the departure point to the destination is set as T time, the irradiation time zone determination unit is -24B / (A + B) <T <0. Alternatively, when the relationship of 24A / (A + B) <T <24 is satisfied, the irradiation time zone of light that can reverse the phase of the biological rhythm is determined as the irradiation time zone, and −24 <T <−. When the relationship of 24B / (A + B) or 0 <T <24A / (A + B) is satisfied, the irradiation time zone of light that can advance the phase of the biological rhythm is determined as the irradiation time zone. May be.

(5) Moreover, the light irradiation apparatus according to the first aspect of the present invention includes an instruction acquisition unit that acquires a lighting or extinguishing instruction, and the irradiation control unit is configured to perform predetermined processing by the light source unit when the lighting instruction is acquired. When the light of the wavelength is irradiated and the turn-off instruction is acquired, the light of the predetermined wavelength by the light source unit may be stopped.

(6) A program according to the second aspect of the present invention provides a computer with a time difference acquisition procedure for acquiring a time difference from a departure place to a destination, the time difference, and a maximum time of phase shift in a phase response curve of biological rhythm. The irradiation time zone determination procedure for determining the irradiation time zone of the irradiation light based on the above, the irradiation intensity determination procedure for determining the irradiation intensity of the irradiation light based on the time difference, and the irradiation time of the irradiation light based on the time difference An irradiation time determination procedure to be determined and an irradiation control procedure to control irradiation of light of a predetermined wavelength from the light source unit are executed. In the irradiation control procedure, the time difference and the maximum time of phase shift in the phase response curve are determined. Based on the above, the number of times of light irradiation is determined, and the light source unit is irradiated with light of the predetermined wavelength by the number of times of irradiation.

  According to the present invention, sleep disorders such as jet lag and fatigue can be efficiently reduced in a short time.

Hereinafter, embodiments of the present invention will be described with reference to the drawings.
FIG. 1 is a block diagram showing a configuration of a light irradiation apparatus 100 according to the first embodiment of the present invention. The light irradiation device 100 includes an information input device 11, a control device 12, a lighting device 13, and a switch 14. The control device 12 includes a time difference acquisition unit 1, an irradiation time zone determination unit 2, an irradiation intensity determination unit 3, an irradiation time determination unit 4, an irradiation control unit 5, an instruction acquisition unit 6, and a phase response curve storage unit 7.

The time difference acquisition unit 1 is connected to the information input device 11, acquires the time difference from the departure point to the destination from the information input device 11, and calculates the time difference from the irradiation time zone determination unit 2, the irradiation intensity determination unit 3, and the irradiation It outputs to the time determination part 4, respectively.
The irradiation time zone determination unit 2 includes a phase response curve stored in the phase response curve storage unit 7, a shift due to a phase advance or a shift due to a phase retraction, and a departure from a start point output from the time difference acquisition unit 1 to a destination. Based on the time difference, the irradiation time zone of the irradiation light irradiated by the illumination device 13 is determined, and the result is output to the irradiation controller 5.
The irradiation intensity determination unit 3 determines the irradiation intensity of the irradiation light irradiated by the illumination device 13 based on the time difference output from the time difference acquisition unit 1 and outputs the result to the irradiation control unit 5.

The irradiation time determination unit 4 determines the irradiation time of the irradiation light based on the time difference output from the time difference acquisition unit 1 and outputs the result to the irradiation control unit 5.
The irradiation controller 5 is based on the irradiation time zone determined by the irradiation time zone determination unit 2, the irradiation intensity determined by the irradiation intensity determination unit 3, and the irradiation time determined by the irradiation time determination unit 4. The irradiation of light having a predetermined wavelength is controlled.
Further, the irradiation control unit 5 causes the illumination device 13 to irradiate light of a predetermined wavelength when a lighting instruction is acquired from the switch 14, and emits light of a predetermined wavelength by the illumination device 13 when acquiring a turn-off instruction. Stop.
The instruction acquisition unit 6 is connected to the switch 14 and acquires a lighting or extinguishing instruction from the switch 14.
The phase response curve storage unit 7 is a storage device such as a memory, and stores a phase response curve of biological rhythm. The phase response curve of the biological rhythm will be described later with reference to FIG.

The information input device 11 is an input device such as a touch panel, and acquires a time difference from a departure place to a destination based on a user operation. The information input device 11 is provided with a storage unit for storing the longitude of each place and the time difference determined based on the difference between the longitudes, and when the user inputs the place name of the departure place and the destination, the difference in longitude is displayed. The time difference corresponding to the difference in the longitude may be read out.
The illumination device 13 (light source unit) irradiates light of a predetermined wavelength based on the control of the irradiation control unit 5. In the present specification, light having a predetermined wavelength means light having a lot of energy in a wavelength region near 464 [nm].
The switch 14 is an input device such as a button, and acquires an instruction to turn on or turn off the lighting device 13 based on a user operation.

FIG. 2 is a flowchart showing processing of the light irradiation apparatus 100 according to the first embodiment of the present invention.
First, the time difference acquisition unit 1 determines whether or not a time difference is acquired from the information input device 11 (step S01). If the time difference is not acquired, NO is determined in step S01, and the time difference acquisition unit 1 proceeds to step S01. On the other hand, when the time difference is acquired, YES is determined in step S01, and the time difference acquisition unit 1 proceeds to step S02.

Then, the irradiation time zone determination unit 2 determines the irradiation time zone based on the time difference input in step S01 (step S02). Next, the irradiation intensity determination unit 3 determines the irradiation intensity based on the time difference input in Step S01 (Step S03).
And the irradiation time determination part 4 determines irradiation time based on the time difference input by step S01 (step S04). Here, the case where the processing is performed in the order of steps S02, S03, and S04 has been described. However, the present invention is not limited to this, and the processing of steps S02 to S04 may be performed in an arbitrary order.

  Next, the instruction acquisition unit 6 determines whether or not a turn-off instruction has been acquired from the switch 14 (step S05). When the turn-off instruction is acquired, YES is determined in step S05, and the instruction acquisition unit 6 determines that the irradiation control unit 5 turns off the illumination device 13 (step S06). On the other hand, when the turn-off instruction has not been acquired, NO is determined in step S05, and the instruction acquisition unit 6 proceeds to step S07.

  And the instruction | indication acquisition part 6 determines whether the lighting instruction | indication is acquired from the switch 14 (step S07). If the lighting instruction has been acquired, the instruction acquisition unit 6 determines YES in step S07, and the irradiation control unit 5 turns on the illumination device 13 (step S08). On the other hand, if the lighting instruction has not been acquired, the instruction acquisition unit 6 determines NO in step S07, and proceeds to step S09.

  And the instruction | indication acquisition part 6 determines whether the present | current time became the irradiation time slot | zone determined by step S02 (step S09). If it is not in the irradiation time zone, the irradiation control unit determines NO in step S09, and proceeds to step S09. On the other hand, if it is the irradiation time zone, the irradiation control unit determines YES in step S09, and the process proceeds to step S10.

And the irradiation control part 5 lights the illuminating device 13 with the irradiation intensity | strength determined by step S03 (step S10).
Next, the irradiation control unit 5 determines whether or not the irradiation time determined in step S04 has elapsed since the lighting device 13 was turned on in step S10 (step S11). If the irradiation time has not elapsed, NO is determined in step S11, and the irradiation control unit 5 proceeds to step S11. On the other hand, if the irradiation time has elapsed, the irradiation control unit 5 determines YES in step S11, and proceeds to step S12.
Then, the irradiation control unit 5 turns off the illumination device 13 (step S12).

  Next, a method for determining the irradiation time zone, irradiation intensity, and irradiation time according to the first embodiment of the present invention will be described. First, the irradiation time zone will be described without considering the energy amount of light having a predetermined wavelength. For example, when moving to a destination with a time difference of 2 hours, the light / dark cycle of the destination is advanced in phase by 2 hours relative to the light / dark cycle of the departure place. Therefore, in order to adjust the biological rhythm to the environment of the destination, the phase of the biological rhythm adapted to the departure place may be advanced by 2 hours.

  FIG. 3 is a graph showing how much the phase of a human biological rhythm shifts depending on the time period of light irradiation. The graph of FIG. 3 shows the phase response curve of the biological rhythm and is stored in the phase response curve storage unit 7. In FIG. 3, an auxiliary line is drawn on the curve g1, and the horizontal axis indicates approximate time information. Regarding the time information on the horizontal axis, since the lowest body temperature appearance time of a healthy person is approximately 3 to 5 o'clock, it is expressed as time information by defining the reference time as 4 o'clock (lower horizontal axis). . This time is set as a reference time. In addition, the time when the effect of the forward and backward of the phase of the biological rhythm due to light irradiation is switched is 5 o'clock, about 1 hour after the reference time. The time zone of light irradiation that can advance the phase of the biological rhythm is the time zone a from 5 o'clock to 13 o'clock, and the phase can be advanced by about 2 hours at the maximum. Conversely, the phase of the biological rhythm can be reversed by light irradiation in the time zone b from 13:00 to 5:00 on the previous day.

  From the above, the light irradiation time zone for eliminating the jet lag is obtained. For example, if the time difference from the departure point moves to a destination of -3 hours, the destination's dawn time or sunset time is 3 hours later than the departure point, that is, the day / night light / dark cycle of the destination starts. 3 hours later than that of the ground. For this reason, the biological rhythm of a general person who has adapted to the light / dark cycle of the destination is also 3 hours later than that of the person who has adapted to the light / dark cycle of the departure place, and is retreated by 3 hours as a phase. Therefore, the biological rhythm adapted to the light / dark cycle at the destination can be adjusted by retreating the phase of the biological rhythm adapted to the light / dark cycle at the starting point for 3 hours, thereby eliminating the jet lag. That is, the jet lag can be eliminated by performing light irradiation in the time zone b of FIG.

Here, the time difference is expressed with a minus sign, but this is minus the time difference of the place between the west side of the departure place and the date change line, and between the east side of the departure place and the date change line. The time difference between places is expressed as a plus.
Also, for example, when moving to a destination with a time difference of 2 hours, the light / dark cycle of the destination is 2 hours earlier than that of the departure place, and the biological rhythm of the person who has adapted to the light / dark cycle of the destination is also the departure place. It is 2 hours earlier than that of the other person, that is, the phase is advanced 2 hours. Therefore, the jet lag can be eliminated by advancing the phase of the biological rhythm adapted to the light / dark cycle of the departure place for 2 hours, and for that purpose, the jet lag is reduced by performing light irradiation in the time zone a of FIG. Can be resolved.

However, as shown in FIG. 3, the advance of the phase of the biological rhythm by one light irradiation is about 2 hours at the maximum, and the backward is about 3 hours. That is, in the phase response curve (FIG. 3) of the biological rhythm stored in the phase response curve storage unit 7, the maximum time of deviation due to phase advance is A time, and the maximum time of deviation due to phase backward is B time. In this case, A = 2 and B = 3. The irradiation time zone determination unit 2 determines the irradiation time zone so as to satisfy the relationship of A <0.8B.
Therefore, when moving to a place where a time difference more than that occurs, multiple times of light irradiation are required.

  For example, when moving to a destination with a time difference of 6 hours, the jet lag can be eliminated by advancing the phase of the biological rhythm for 6 hours. The number of times of light irradiation necessary for this is 3 times obtained by dividing the time difference of 6 hours by the time A (= 2 hours) at which the phase advance is maximum. However, the second light irradiation time zone needs to be advanced by 2 hours from the first light irradiation time zone. This is because the phase of the biological rhythm has already advanced by 2 hours by the first light irradiation. If the biological rhythm that has already been advanced for 2 hours is further advanced for 2 hours, it will be advanced for a total of 4 hours. Further, similarly, the third light irradiation time zone is advanced by 2 hours from the second light irradiation time zone, so that the phase can be advanced for 6 hours, and the jet lag can be eliminated.

  FIG. 4 is a diagram for explaining a method of eliminating the jet lag of 6 hours by performing irradiation with the illumination device 13 three times. The horizontal axis of FIG. 4 shows the time difference between the biological rhythm adapted to the light / dark rhythm of the departure place and the biological rhythm adapted to the light / dark cycle of the destination. Since the time difference is 6 hours before the light irradiation, the phase difference between the biological rhythm adapted to the light / dark cycle of the departure place and the biological rhythm adapted to the light / dark rhythm of the destination is 6 hours. The phase of the biological rhythm can be advanced by 2 hours by the first light irradiation. Therefore, the time difference after the first light irradiation is reduced to 4 hours. Similarly, the time difference is reduced to 2 hours by the second light irradiation, and the time difference becomes 0 by the third light irradiation. As a result, the biological rhythm adapts to the light and dark rhythm of the destination, and the jet lag of 6 hours is eliminated.

  By using the above method, even when moving to a destination with a larger time difference, it is possible to efficiently reduce the jet lag. This is the same when moving to a destination where the time difference is negative. In that case, the phase of the biological rhythm may be set back by light irradiation, and the second light irradiation time zone may be delayed from the previous light irradiation time zone. However, since the maximum time B (see FIG. 3) in which the phase of the biological rhythm is retreated is about 3 hours, the time for delaying the light irradiation time zone is 3 hours.

  Next, a description will be given of which of the light irradiation that advances the phase of the biological rhythm and the light irradiation that moves backward can effectively eliminate the jet lag with a small number of light irradiations. From the methods described so far, if the time difference is positive, light irradiation that advances the phase of the biological rhythm is performed, and if it is negative, light irradiation that reverses the light may be performed, but this method is appropriate depending on the degree of the time difference. It may not be.

  FIG. 5 is a diagram illustrating a case where the time difference between the departure point and the destination is −18 hours. In FIG. 5, the inner circle C1 is the earth, and the starting point when viewed from the north pole P1 and the position of the destination located at a time difference of -18 hours from the starting point are shown. When the light irradiation time is determined from the sign of the time difference, since the sign is negative, light irradiation that reverses the phase of the biological rhythm may be performed. The number of times of light irradiation required at this time is a maximum of approximately 3 hours for the backward phase of the biological rhythm, so | -18/3 | = 6 times of light irradiation is required. However, as shown in FIG. 5, the destination where the time difference of −18 hours occurs is the time difference when considering the westbound direction from the starting point. The difference in time is 6 hours. Therefore, if the jet lag is to be eliminated by performing light irradiation for advancing the phase of the biological rhythm, the advance time is 2 hours at the maximum, so | 6/2 | = 3 times of light irradiation is sufficient. Therefore, performing light irradiation for advancing the phase of the biological rhythm is less efficient and more efficient.

As described above, the number of times of light irradiation required for each is used for selecting whether to advance or reverse the phase of the biological rhythm. And the smaller the number of times of light irradiation, the shorter the jet lag can be done and the less the burden on the user. Therefore, the one with the smaller number of times of light irradiation is selected.
Therefore, the time difference between the points where the number of times of light irradiation necessary for eliminating the jet lag by the advance of the phase of the biological rhythm and the number of times of light irradiation necessary for eliminating the jet lag by the backward movement are equal is obtained. Based on the time difference at that point, it is easy to determine whether light irradiation that advances the phase of the biological rhythm should be performed or light irradiation that makes it move backward depending on the magnitude relationship between the time difference between the destination and that point. Can do.

  First, the case where the time difference of the destination is negative will be described. The maximum time to advance the phase of the biological rhythm is A time, the maximum time to reverse is the B time, the time difference of the destination is T, the number of times of light irradiation necessary to reduce the jet lag by advancing the phase of the biological rhythm When the number of times of light irradiation necessary to reduce the jet lag by retreating Na and the phase of the biological rhythm is Nb, the following relations (1-1) and (1-2) are established.

Na = (24 + T) / A (1-1)
Nb = −T / B (1-2)

  Here, the time difference T at which Na = Nb is a time difference serving as a reference for selecting light irradiation (hereinafter referred to as a reference time difference), and when T is obtained from the expressions (1-1) and (1-2), (1-3) is established.

    T = −24B / (A + B) (1-3)

The reference time difference T can be obtained by substituting specific numerical values of the maximum time A that advances the phase of the biological rhythm and the maximum time B that moves backward in this equation (1-3).
However, this is limited to the case where the time difference of the destination is negative. When the time difference of the destination is positive, if the same as in the case of negative, the relationship of the following formulas (2-1), (2-2), and (2-3) with respect to Na and Nb and the reference time difference T is It holds.

Na = (24−T) / B (2-1)
Nb = T / A (2-2)
T = 24A / (A + B) (2-3)

  The reference time difference T is obtained by substituting the biological rhythm phase forward time and backward time into the equations (1-3) and (2-3). Therefore, the irradiation time zone determination unit 2 determines the time between 14:00 and 5:00 at the departure time when the relationship of −24B / (A + B) <T <0 or 24A / (A + B) <T <24 is satisfied. If the zone is determined as the irradiation time zone and the relationship of −24 <T <−24B / (A + B) or 0 <T <24A / (A + B) is satisfied, the time between 5 o'clock and 14 o'clock at the departure time The belt is determined as the irradiation time zone.

In the above description of the light irradiation method for advancing or retreating the phase of the biological rhythm, the biological rhythm advance effect and the backward effect have been described as about 2 hours. However, when more accurate values are read from FIG. The phase advance time is a maximum of 1.8 hours and the reverse time is a maximum of 3.2 hours.
When the reference time difference is obtained using these pieces of information, T = −15.4 when the time difference is negative, and T = 8.6 when the time difference is positive. The irradiation time zone determination unit 2 sets the time zone between 14:00 and 5:00 as the irradiation time zone when the relationship of −15.4 <T <0 or 8.6 <T <24 is satisfied. decide. On the other hand, the irradiation time zone determination unit 2 irradiates the time zone between 5 o'clock and 14 o'clock at the departure time when the relationship of −24 <T <−15.4 or 0 <T <8.6 is satisfied. It is determined as a time zone.
By performing such processing in the irradiation time zone determining unit 2, it is possible to reduce the jet lag in a short time.

  FIG. 6 is a diagram for explaining at which point the reference time difference T is from the departure point. FIG. 6 is a view of the state where the innermost circle C1 is regarded as the earth and viewed from the north pole P1, similarly to FIG. 5, and the point of the reference time difference obtained from FIG. The outermost circle C11 shows a positive time difference, and the inner circle C12 shows a negative time difference. The light irradiation time zone can be determined based on the time difference between the points located at Tp. As shown in FIG. 6, the reference time difference T is not 12 hours or -12 hours located on the opposite side from the starting point through the center of the earth. This is because the reference time difference T is obtained from the values of the maximum time A for which the biological rhythm advances and the maximum time B for which the biological rhythm advances, and the respective effects are not equal.

  Next, the energy of light that the irradiation control unit 5 irradiates the illumination device 13 will be described. Advancing or retreating the arousal level or the phase of the biological rhythm has a large relationship not only with the light irradiation time zone but also with the energy of light. The more energy that is incident on the retina, the greater the effect. By obtaining the minimum light energy required for the advance or retreat of the phase of the biological rhythm, more efficient light irradiation and jet lag reduction can be achieved.

When light is expressed as energy, the concept of radiant flux is used. This is radiant energy passing through a certain surface per unit time, and the unit is represented by [W]. Moreover, the radiant flux of the light radiated | emitted per unit area is called irradiance, and a unit is represented by [W / m < ² >]. In this way, a physical quantity that considers space, time, and wavelength with respect to the energy quantity of light radiated into the space is called a radiation quantity. However, the amount of radiation is not taken into account until it appears to the human eye. For example, light such as infrared rays is not visible light even if it has a lot of energy, so human eyes cannot see it and it does not feel dazzling.

  The amount obtained by applying the sensitivity to the light of the human eye to the amount of radiation is called a photometric amount, and the unit of the amount of radiation corresponds to the photometric amount. For example, a light flux that considers the sensitivity of the human eye to the radiant flux and a illuminance that considers the sensitivity of the human eye to the irradiance. The sensitivity of the human eye is called visual sensitivity, but this depends on the wavelength of light. In photopic vision, light of 555 [nm] is felt brightest in the visible light region from 380 [nm] to 780 [nm], and the visibility at this time is called maximum visibility. This maximum visual sensitivity is set to 1, and relative visual sensitivity at other wavelengths is referred to as specific visual sensitivity. Furthermore, a numerical value standardized by the International Commission on Illuminance regarding the specific luminous efficiency is called an aiming specific luminous sensitivity, and a curve representing it is called a standard specific luminous curve.

  FIG. 7 is a graph showing a standard relative luminous sensitivity curve. The horizontal axis in FIG. 7 represents the wavelength of light (visible light region), and the vertical axis represents the relative luminous sensitivity of each wavelength. From FIG. 7, the sensitivity to the wavelength of human light is highest at 555 [nm], and the sensitivity decreases around that. The luminous flux is obtained by multiplying the specific luminous sensitivity at each wavelength, the radiant flux, and the maximum luminous efficacy (a value relating the photometric amount and the radiation amount), and adding, that is, integrating in the visible light region.

  The above is expressed by a formula. When the radiant flux at a certain wavelength is expressed as Φ [W / nm], the standard relative luminous sensitivity as V, and the maximum luminous effectiveness [lm / W] as K, the luminous flux is expressed by the following equation (3-1). Can do.

Similarly, when the irradiance is expressed as Φa [W / m ² ], the illuminance is expressed by Expression (3-2).

Here, in order to obtain the illuminance, the value of irradiance at each wavelength is required. This is the relative spectral distribution in which the value of irradiance at each wavelength is expressed as a relative value, and the energy of the wavelength having the highest energy. Can be determined by the value of.
The relative spectral distribution is a graph showing the maximum energy of each wavelength in the light source as 1, and the energy of other wavelengths as a relative value with respect to that, and shows a general spectral distribution of illumination. It is used for.

FIG. 8 is a graph showing the relative spectral distribution. FIG. 8 shows the relative spectral distribution of a general fluorescent lamp, the horizontal axis indicates the wavelength, and the vertical axis indicates the relative value of the energy of each wavelength. This light source has a peak in the vicinity of about 540 [nm], energy at the wavelength is set to 1, and energy at other wavelengths is expressed as a relative value thereto. Therefore, the energy of other wavelengths is a value obtained by adding the relative value of the desired wavelength to the energy of the wavelength having a relative value of 1. From the above, when the energy of the wavelength having the highest energy is expressed as Φmax [lm · m ² / nm] and the relative value of each wavelength relative thereto is expressed as R (λ), the illuminance is expressed by the following equation (3-3). Can be expressed.

  However, the photometric quantity such as illuminance is energy that considers how the light looks to the human eye, and does not indicate the effect on the human biological rhythm. As described above, it is a sleep-related hormone called melatonin that is greatly related to human biological rhythm, and its inhibition rate is represented by FIG. Therefore, if the melatonin secretion inhibition rate shown in FIG. 1 is used instead of the standard spectral relative luminous sensitivity V (λ) in the equation (3-3), the energy affecting the melatonin inhibition can be obtained. It can be considered as energy that affects the rhythm. When the suppression rate of melatonin is Vm and the energy that affects the suppression of melatonin secretion is expressed using irradiance, the following equation (3-4) is obtained.

  Using formula (3-4), energy that affects biological rhythm is obtained. From the light irradiation condition in the light irradiation experiment for obtaining the phase response curve of FIG. 3, the energy required for the advance or retreat of the phase of the biological rhythm can be obtained.

  FIG. 9 is a diagram showing light irradiation conditions in a light irradiation experiment for obtaining a phase response curve. FIG. 9 shows the light irradiation conditions from the start to the end of the experiment and the conditions of the task imposed on the subject in time series, and the conditions are roughly divided into four. In 3 minutes immediately after the start of the experiment, the illuminance is gradually increased from approximately 15 [lx] to 10000 [lx], and during this time, the subject is gazing at the target near the ceiling (condition 1). In the next 6 minutes, the illuminance is 10,000 [lx], but there is no particular gaze instruction, and the illuminance condition is substantially 5000 [lx] to 9000 [lx] (condition 2). In the next 6 minutes, the user is gazing at an illuminance of 10000 [lx] (condition 3). However, for conditions 2 and 3, these two conditions are set as one set and are repeated 33 times. That is, the irradiation control unit 5 irradiates the illumination device 13 with light having a predetermined wavelength a plurality of times. In the last 3 minutes, the illuminance is gradually decreased from 10000 [lx] to 15 [lx] at the light irradiation end time, and during this time, the subject is gazed (condition 4).

  In the condition 1 and the condition 4, the actual amount of light irradiated to the subject is light irradiation for 3 minutes at an illuminance of 4993 [lx] which is between 10000 [lx] and 15 [lx]. equal. Therefore, the illuminance in these time zones is 4993 [lx]. Similarly, in condition 2, since the illumination condition is substantially 5000 [lx] to 9000 [lx], it is 7000 [lx] between them. Condition 3 is 10000 [lx].

From the above illuminance conditions, the light irradiation energy by the illuminating device 13 used in the experiment is obtained, and then the energy affecting the biological rhythm is obtained. Actually, Φmax is obtained by substituting the value of illuminance under each condition into Equation (3-3), and the irradiance at each wavelength is obtained using this. By substituting the calculated irradiance and the value of the relative spectral distribution into the equation (3-4), the energy per unit time affecting the biological rhythm can be obtained, and the time spent for each condition is integrated. Thus, the energy [J / m ² ] in the entire experiment is obtained.

When the energy was calculated | required with the above method, it was about 6.4 [kJ / m < ² >]. Therefore, by performing light irradiation with energy equivalent to this, the biological rhythm can be adjusted and the time difference can be reduced. However, the illuminance and light irradiation time conditions need not be exactly the same as the experimental conditions. The balance between the energy per unit time and the light irradiation time may be adjusted within a possible range. For example, when it is desired to reduce the time difference with a light irradiation time shorter than that of the experiment, the energy per unit time may be increased by increasing the illuminance of light. Conversely, it is also possible to decrease the illuminance and increase the light irradiation time. Furthermore, if the illumination device 13 that irradiates light having a lot of energy in a light region of a predetermined wavelength, the jet lag can be eliminated in a short time even with a small light emission amount.
With the above method, the jet lag can be efficiently reduced in a short time.

  FIG. 10 is a view showing a light irradiation apparatus 100a according to the second embodiment of the present invention. The light irradiation device 100a is adapted to an aircraft which is a general means for moving to a destination at high speed. In the present embodiment, an information input device 11 for inputting information of a departure place and a destination, a control means 12 for obtaining a time difference from the inputted information and controlling a light emission amount and a light emission time of the light source, and at least a predetermined wavelength The illumination device 13 includes a light source that irradiates the light and a switch 14 that can switch the light source on and off. Since the functions of the information input device 11, the switch 14, the control device 12, and the lighting device 13 are the same as those in FIG. 1, their descriptions are omitted.

In this embodiment, the user M of the aircraft uses the information input device 11 to input the time information of the departure point and the destination, so that the light irradiation suitable for reducing the jet lag is given to the user M. On the other hand, it is performed by the lighting device 13.
Here, the person who inputs information to the information input device 11 may be an aircraft user M or an airline related person (such as a flight attendant). The information input to the information input device 11 may be time information of a departure place and a destination, but is not limited thereto. For example, the name of the place of departure and destination may be used, or the name of the place of departure and destination may be selectable. In other words, the information to be input only needs to be information that can identify the time information of the departure point and the destination, and the information of the departure point and the destination may be used as electronic information by electronic devices in the aircraft. Therefore, the information may be automatically acquired and reflected on the control device 12 without using the input device 11.

  In addition, an airline official can operate the switch 14 to turn off the light source provided in the lighting device 13 at an arbitrary timing. The light source provided in the illuminating device 13 may be of any type as long as it emits light of a predetermined wavelength. Any light source may be used as long as it can be used for lighting such as fluorescent lamps and LEDs (Light Emitting Diodes). In addition, a light source that emits light having a different color temperature from a light source that emits light of a predetermined wavelength may be used in combination. In that case, the control device 12 adjusts the intensity of various light sources, and irradiates the user M with light having a color temperature that does not give a sense of incongruity. It is also possible to use only a light source having a color temperature different from that of the light source that emits light of a predetermined wavelength.

  The light irradiation apparatus 100a has been described as applied to a moving body that moves at high speed to a destination such as an aircraft. However, the moving body is not limited to this, and may be a destination where a time difference occurs such as a night train or a night bus. It can also be applied to other mobile objects that can be used to move It can also be used to reduce sleep disorders and fatigue, such as shift workers and people with rhythm disorders.

  FIG. 11 is a view showing a light irradiation apparatus 100b according to the third embodiment of the present invention. The light irradiation device 100b includes an information input device 11, a control device 12, a lighting device 23 that irradiates the periphery of the user M with a light source that emits light of at least a predetermined wavelength, and a switch that includes means for switching the light source on and off. 14. The functions of the information input device 11, the switch 14, the control device 12, and the lighting device 23 are the same as those of the information input device, the switch, the control device, and the lighting device in FIG.

  The light irradiation device 100b is applied to a reading light provided at each seat, which can be personally used by the user M. The user M can use the switch 14 to select whether or not to use light irradiation suitable for reducing the jet lag. When using light irradiation, light irradiation is performed by the same method as that of the light irradiation apparatus 100a. When not using the light irradiation, switching on / off of the light source provided in the lighting apparatus 23 is switched at an arbitrary timing of the user M. Is possible.

  Here, the light source provided in the illumination device 23 may be of any type as long as it emits light of a predetermined wavelength. Any light source may be used as long as it can be used for illumination including fluorescent lamps and LEDs. Furthermore, a light source that emits light having a different color temperature from a light source that emits light of a predetermined wavelength may be used in combination. In this case, the control device 12 adjusts the intensity of various light sources, and irradiates the user M with light having a color temperature that does not give a sense of incongruity. It is also possible to use only a light source having a color temperature different from that of the light source that emits light of a predetermined wavelength.

  The light irradiation device 100b has been applied to a means for moving to a destination such as an aircraft at high speed. However, the movement means is not limited to this, and for moving to a destination where a time difference occurs such as a night train or a night bus. It can also be applied to other available transportation means. Further, the place of use is not limited to the moving means, and may be provided inside a building, for example. Furthermore, the form is not limited to the reading light, but may be any form that can illuminate a personal space.

  FIG. 12 is a view showing a light irradiation apparatus 100c according to the fourth embodiment of the present invention. The light irradiation device 100c includes an information input device 11, a control device 12, a lighting device 33 including a light source that emits light of at least a predetermined wavelength, a display device 35 that performs display using the lighting device 33, and a light source. The switch 14 is provided with means for switching on / off and switching the power of the display device 35 on and off. The functions of the information input device 11, the switch 14, and the control device 12 are the same as those of the information input device, the switch, and the control device in FIG.

  The light irradiation device 100c is applied to a display device that a user views. The user M can browse the information displayed on the display device 35 and can receive light irradiation suitable for reducing the jet lag by the light source used for the information. Further, at any timing of the user M, the light source provided in the illumination device 33 can be turned on and off, and the power of the display device 35 can be switched on and off.

  Here, the light source provided in the illumination device 33 may be of any type as long as it emits light of a predetermined wavelength. Any light source that can be used for illumination such as a backlight or LED may be used, and a light source that emits light of a different color from a light source that emits light of a predetermined wavelength may be used together. In that case, the control device 12 adjusts the intensity of various light sources, and irradiates the user M with light having a color temperature that does not give a sense of incongruity. It is also possible to use only a light source having a color temperature different from that of the light source that emits light of a predetermined wavelength.

  The light irradiation apparatus 100c has been described as applied to a means for moving to a destination such as an aircraft at high speed. However, the movement means is not limited to this, and a destination such as a night train or a night bus may be used. The present invention can also be applied to other moving means that can be used for movement. Further, the place of use is not limited to the moving means, and may be provided inside a building, for example.

  FIG. 13 is a view showing a light irradiation apparatus 100d according to the fifth embodiment of the present invention. Here, the light irradiation device 100d is applied to a portable mobile phone. The light irradiation device 100d includes an information input unit 41, a control device 42 built in the medium 46, an illumination device 43 including a light source that emits light of at least a predetermined wavelength built in the medium 46, and a display device 45. The switch 44 includes means for switching on / off the light source and switching the power of the display device 45 on and off, and a medium 46 for holding them all. The functions of the information input unit 41, the control device 42, the lighting device 43, and the switch 44 are the same as those of the information input device, the control device, the lighting device, and the switch in FIG.

  The light irradiation device 100d is applied to a mobile phone that can be personally used by a user and portable. The user can enjoy the information displayed using the display device 45, and by inputting the time information of the departure point and the destination to the information input unit 41, while enjoying the displayed information, the jet Light irradiation suitable for reducing the lag can be received through the display device 45. Further, the user can use the switch 46 to turn on and off the light source provided in the lighting device 43 and turn on and off the power of the display device 44 at an arbitrary timing.

  Here, examples of information to be input to the information input unit 41 include time information of a departure place and a destination, but are not limited thereto. In addition, when using time information, it is generally possible to store the time information in a mobile phone, so that the information may be automatically used and reflected in the control device 42. Alternatively, the time information may be obtained from the outside using a communication means and reflected. Further, the light source provided in the illumination device 43 may be of any type as long as it emits light of a predetermined wavelength. Any light source can be used as long as it can be used for portable lighting devices such as LEDs and backlights. In addition, a light source that emits light having a color temperature different from that of the light source that emits light of a predetermined wavelength may be used together. In that case, the control device 42 adjusts the intensity of various light sources, and irradiates the user M with light having a color temperature that does not give a sense of incongruity. In addition, it is possible to use only a light source having a color temperature different from that of the light source that emits light of a predetermined wavelength.

  The light irradiation device 100d has been described as applied to a mobile phone, but is not limited thereto. The present invention can also be applied to other devices that are portable and have the function of a display device.

  FIG. 14 is a view showing a light irradiation apparatus 100e according to the sixth embodiment of the present invention. Here, the light irradiation device 100e is applied to a light irradiation device that can be carried by a user. The light irradiation device 100 e includes an information input unit 41, a control device 42 built in the medium 46, an illumination device 53 including a light source that emits light of at least a predetermined wavelength built in the medium 46, and a display device 44. , A medium 46 that holds all of these, and a switch 44 that includes means for switching on / off of the light source. The functions of the information input unit 41, the control device 42, the lighting device 53, and the switch 44 are the same as those of the information input device, the control device, the lighting device, and the switch in FIG.

  The light irradiation device 100e is applied to a light irradiation device that can be personally used by a user and portable. The user can receive light irradiation suitable for reducing the jet lag from the lighting device 53 by inputting the time information of the departure point and the destination to the information input unit 41. In addition, the user can use the switch 44 to switch on and off the light source provided in the illumination device 43 at an arbitrary timing.

Here, the light source provided in the illumination device 53 may be of any type as long as it emits light of a predetermined wavelength. Any light source can be used as long as it can be used for portable lighting devices such as LEDs and backlights. Furthermore, a light source that emits light having a different color temperature from a light source that emits light of a predetermined wavelength may be used in combination. In that case, the control device 42 adjusts the intensity of various light sources, and irradiates the user M with light having a color temperature that does not give a sense of incongruity. In addition, it is possible to use only a light source having a color temperature different from that of the light source that emits light of a predetermined wavelength.
The light irradiation device 100e has been described as applied to a portable light irradiation device, but is not limited thereto. It is portable and can be applied to other devices that emit light.

  As described above, when the light irradiation apparatus according to the first to sixth embodiments of the present invention is used, the irradiation time zone, intensity, and irradiation time of light of a predetermined wavelength using the time information of the departure place and the destination. By irradiating with light of a predetermined wavelength adjusted, jet lag can be efficiently reduced in a short time. In addition, the light irradiation device according to the embodiment of the present invention shifts the phase difference of the sleep / wake cycle between the shift worker such as the night worker and the normal worker as the time difference in the jet lag described above. It can also be applied to workers.

  In the embodiment described above, the functions of the time difference acquisition unit 1, the irradiation time zone determination unit 2, the irradiation intensity determination unit 3, the irradiation time determination unit 4, the irradiation control unit 5, the instruction acquisition unit 6 in FIG. Even if the program for realizing a part of the function is recorded on a computer-readable recording medium, the program recorded on the recording medium is read into a computer system and executed to control the light irradiation apparatus. Good. Here, the “computer system” includes an OS and hardware such as peripheral devices.

  The “computer-readable recording medium” refers to a storage device such as a flexible medium, a magneto-optical disk, a portable medium such as a ROM and a CD-ROM, and a hard disk incorporated in a computer system. Further, the “computer-readable recording medium” dynamically holds a program for a short time, like a communication line when transmitting a program via a network such as the Internet or a communication line such as a telephone line. In this case, it is also assumed that a server that holds a program for a certain time, such as a volatile memory inside a computer system that serves as a server or client. The program may be a program for realizing a part of the functions described above, and may be a program capable of realizing the functions described above in combination with a program already recorded in a computer system.

  The embodiment of the present invention has been described in detail with reference to the drawings. However, the specific configuration is not limited to this embodiment, and includes designs and the like that do not depart from the gist of the present invention.

It is a block diagram which shows the structure of the light irradiation apparatus 100 by the 1st Embodiment of this invention. It is a flowchart which shows the process of the light irradiation apparatus 100 by the 1st Embodiment of this invention. It is the graph which showed how much the phase of a human biological rhythm shifted | deviated with the time zone of light irradiation. It is a figure for demonstrating the method of eliminating the jet lag of 6 hours by performing irradiation by the illuminating device 13 3 times. It is a figure explaining the case where the time difference of the departure place and the destination is -18 hours. It is a figure for demonstrating in which point the reference | standard time difference T exists from a departure place. It is a graph which shows a standard specific visibility curve. It is a graph which shows a relative spectral distribution. It is a figure which shows the light irradiation conditions in the light irradiation experiment for calculating | requiring a phase response curve. It is the figure which showed the light irradiation apparatus 100a by the 2nd Embodiment of this invention. It is the figure which showed the light irradiation apparatus 100b by the 3rd Embodiment of this invention. It is the figure which showed the light irradiation apparatus 100c by the 4th Embodiment of this invention. It is the figure which showed the light irradiation apparatus 100d by the 5th Embodiment of this invention. It is the figure which showed the light irradiation apparatus 100e by the 6th Embodiment of this invention. It is a graph which shows the relationship between the magnitude | size of the influence which acts on the wavelength of light, and melatonin secretion. It is a graph which shows the relationship between the time slot | zone which irradiates light, and the magnitude | size of the advance effect of the phase of a biological rhythm, or the reverse effect by it.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Time difference acquisition part, 2 ... Irradiation time zone determination part, 3 ... Irradiation intensity determination part, 4 ... Irradiation time determination part, 5 ... Irradiation control part, 6 ... Instruction acquisition , 7 ... Phase response curve storage unit, 10 ... Control device, 11 ... Information input device, 12 ... Control device, 13 ... Lighting device, 14 ... Switch, 23 ...・ Lighting device 33 ... Lighting device 35 ... Display device 41 ... Information input unit 42 ... Control device 43 ... Lighting device 44 ... Switch 45 ... Display device, 46 ... medium, 53 ... lighting device, 100, 100a to 100e ... light irradiation device

Claims (6)

A light source unit that emits light of a predetermined wavelength;
A time difference acquisition unit for acquiring the time difference from the departure place to the destination;
An irradiation time zone determination unit that determines an irradiation time zone of irradiation light based on the time difference and the maximum time of phase shift in the phase response curve of the biological rhythm ;
An irradiation time determination unit for determining the irradiation time of the irradiation light based on the time difference;
And a radiation control unit for controlling the irradiation of light of the predetermined wavelength from the front Symbol source unit,
The irradiation control unit determines the number of times of light irradiation based on the time difference and the maximum time of phase shift in the phase response curve, and irradiates the light source unit with light of the predetermined wavelength by the number of times of irradiation. The light irradiation apparatus characterized by making it do.   The light source device according to claim 1, wherein the light source unit irradiates light having a lot of energy in a wavelength region near 464 [nm] as the light having the predetermined wavelength.   The irradiation control unit controls irradiation of light from the light source unit based on an irradiation time and an energy value of predetermined light in the irradiation time zone determined by the light irradiation time zone determination unit. The light irradiation apparatus according to claim 2. A phase response curve storage unit for storing a phase response curve of a biological rhythm;
In the phase response curve, when the maximum time of deviation due to phase advance is A time, the maximum time of deviation due to phase backward is B time, and the time difference from the starting point to the destination is T time,
The irradiation time zone determination unit, when satisfying the relationship of −24B / (A + B) <T <0 or 24A / (A + B) <T <24 , When the irradiation time zone is determined as the irradiation time zone and the relationship of −24 <T <−24B / (A + B) or 0 <T <24A / (A + B) is satisfied , the biological rhythm phase is advanced. The light irradiation apparatus according to claim 1, wherein an irradiation time zone of light that can be emitted is determined as the irradiation time zone. Provided with an instruction acquisition unit for acquiring an on / off instruction,
The irradiation control unit irradiates light of a predetermined wavelength by the light source unit when acquiring a lighting instruction, and stops irradiation of light of a predetermined wavelength by the light source unit when acquiring a turn-off instruction. The light irradiation apparatus according to any one of claims 1 to 4 . On the computer,
Time difference acquisition procedure to acquire the time difference from the departure point to the destination,
An irradiation time zone determination procedure for determining an irradiation time zone of irradiation light based on the time difference and the maximum time of phase shift in the phase response curve of the biological rhythm ;
An irradiation intensity determination procedure for determining the irradiation intensity of the irradiation light based on the time difference;
An irradiation time determination procedure for determining the irradiation time of the irradiation light based on the time difference;
To execute an irradiation control step of controlling the irradiation of light of a predetermined wavelength from the light source unit,
In the irradiation control procedure, the number of times of light irradiation is determined based on the time difference and the maximum time of phase shift in the phase response curve, and the light source unit is irradiated with light of the predetermined wavelength by the number of times of irradiation. Program to let you .

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