JP4968774B2 - Cream composition - Google Patents

Description

  The present invention relates to a cream composition. In more detail, even when polar oils that generally affect the viscosity stability of the preparation are blended, the stability is good in a wide temperature range from high to low, and there is no stickiness and the skin spreads well. The present invention relates to an oil-in-water (O / W) emulsification type cream composition having a good feel.

  Methods for preparing an emulsified composition such as cream include a method using a nonionic surfactant and a higher alcohol, a method using an anionic surfactant and a higher alcohol, a method using a cationic surfactant, a method using a fatty acid soap, and A method of using them together is known.

  In the emulsified composition, a polar oil may be blended as an active ingredient for the skin and for the purpose of improving the spread on the skin without sticking to the touch. However, in general, it is known that the viscosity reduction phenomenon occurs at a high temperature due to the blending of the polar oil, and it is necessary to change the blending components of the system in order to cope with this phenomenon. Specifically, methods for increasing the blending amount of surfactants, higher alcohols, soaps and the like are known. Japanese Patent Application Laid-Open No. 2001-2553 (Patent Document 1) describes a method in which an N-alkylmethyl taurine salt is used in combination with a nonionic surfactant.

  However, when a surfactant, higher alcohol, soap, or the like is added in a high amount, the spread is heavy and an undesirable feeling of use such as stickiness is generated.

  Moreover, in the method of using N-alkylmethyl taurate in combination with a nonionic surfactant, sufficient viscosity required as an emulsified composition may not be obtained, and stability when stored at high temperatures is not sufficient.

  In addition, the present applicant has previously used a higher alcohol, a long-chain acyl sulfonate anionic surfactant and water, and has a specific NMR value and melting point, which may affect the stability of the preparation. Even when a large amount of ascorbic acid-2-glucoside is added, a gel composition having good stability in a wide temperature range from high temperature to low temperature and having a good feeling to use, and a cream composition using the same in the outer phase are obtained. (See Patent Document 2). However, in this patent document 2, the examination about the stable mixing | blending of polar oil was not performed.

JP 2001-2553 A JP 2005-132808 A

  The present invention was made in view of the above circumstances, and even when a polar oil component that affects the viscosity stability of the preparation is blended, the stability is good in a wide temperature range from high temperature to low temperature, and there is no stickiness. An object of the present invention is to provide an oil-in-water emulsification type cream composition that has a good feel on use and has a good feeling on use.

In order to achieve the above object, the present invention includes the following components (a) to (d), the blending ratio (molar ratio) of the component (a) to the component (b) is 3 or more, and the viscosity of the system is 8, 000mPa · s (B-type viscometer, 30 ° C.) Ri der above, when a polar oil having a molecular weight over 400, the amount provides an der Ru cream composition most 1 mass%.
Component (a): One or more higher alcohols selected from stearyl alcohol, batyl alcohol, and behenyl alcohol.
(B) Component: A long-chain acyl sulfonate type anionic surfactant represented by the following general formula (I).

_{R 1 CO-a- (CH 2} ) n SO 3 M 1 (I)

[In the formula (I), R ₁ CO— represents a saturated or unsaturated fatty acid residue (acyl group) having an average carbon number of 10 to 22; a represents —O— or —NR ₂ — (where R ₂ Represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms); M ₁ represents a hydrogen atom, an alkali metal, an alkaline earth metal, ammonium or an organic amine; n represents 1 to 3 Indicates an integer. ]
(C) Component: One or two or more polar oils having a molecular weight of 400 or less selected from octanoic acid ester, isooctanoic acid ester, palmitic acid ester, adipic acid diester, isononanoic acid ester, and succinic acid diester .
(D) Component: Water.

  Moreover, this invention provides the said cream composition whose compounding ratio (molar ratio) of (a) component with respect to (b) component is 4-10.

  Moreover, this invention provides the said cream composition which contains 5-30 mass% of (c) component in the composition whole quantity.

  Moreover, this invention provides the said cream composition whose (b) component is N-stearoyl-N-methyltaurine salt.

  Moreover, this invention provides the said cream composition whose (a) component consists of 2 or more types of higher alcohol.

  Moreover, this invention provides the said cream composition by which a nonionic surfactant is mix | blended more than 0.3 mass% in the composition whole quantity.

  The present invention also provides the above cream composition substantially free from polar oils having a molecular weight of more than 400.

  Moreover, this invention provides the said cream composition which is cosmetics.

  According to the present invention, even when polar oils that generally affect the viscosity stability of the preparation are blended, in a wide temperature range from high temperature to low temperature, there is no precipitation of higher alcohol crystals, etc., and stable blending is possible. Thus, an oil-in-water emulsified type cream composition can be obtained which does not have a low viscosity, and does not have stickiness and has a good feeling of spreading on the skin.

  The higher alcohol as the component (a) in the present invention is particularly limited as long as it has an average alkyl chain length of 18 or more obtained by arithmetic average and can be used in the fields of cosmetics, pharmaceuticals, quasi drugs and the like. Examples thereof include saturated linear monohydric alcohols and unsaturated monohydric alcohols. As saturated linear monohydric alcohols, octadecanol (= stearyl alcohol), nonadecanol, icosanol (= aralkyl alcohol), heenicosanol, docosanol (= behenyl alcohol), tricosanol, tetracosanol (= carnerville alcohol), pentacosa Nord, hexacosanol (= seryl alcohol) and the like. Examples of unsaturated monohydric alcohols include elaidyl alcohol. In the present invention, a saturated linear monohydric alcohol is preferable from the viewpoint of stability and the like.

  When the average alkyl chain length of the higher alcohol as the component (a) is less than 18, the melting point of the cream composition becomes low and the high temperature stability is not sufficient. The preferred upper limit of the average alkyl chain length is not particularly limited, but the upper limit of the average alkyl chain length is preferably about 26, more preferably about 24, and particularly preferably about 22. .

  The component (a) can be used singly or in combination of two or more. In the present invention, the use of two or more different alkyl chains means that the prevention of precipitation of the component (a) is realized in terms of formulation design. It is preferable from the point of view.

  The long chain acyl sulfonate type anionic surfactant as the component (b) of the present invention is represented by the following general formula (I).

_{R 1 CO-a- (CH 2} ) n SO 3 M 1 (I)

In the general formula (I), R ₁ CO— represents a saturated or unsaturated fatty acid residue (acyl group) having an average carbon number of 10 to 22. As R ₁ CO, C ₁₁ H ₂₃ CO, C ₁₂ H ₂₅ CO, C ₁₃ H ₂₇ CO, C ₁₄ H ₂₉ CO, C ₁₅ H ₃₁ CO, C ₁₆ H ₃₃ CO, C ₁₇ H ₃₅ CO, coconut fatty acid residue Groups, palm palm fatty acid residues and the like. R ₁ CO is more preferably one having an average carbon atom number of 12 to 22 from the viewpoint of safety and the like.

a represents -O- or -NR- (wherein R represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms). These are electron donating groups. a is preferably —O—, —NH—, or —N (CH ₃ ) —.

M ₁ represents a hydrogen atom, an alkali metal, an alkaline earth metal, ammonium or an organic amine. Examples of M ₁ include lithium, potassium, sodium, calcium, magnesium, ammonium, monoethanolamine, diethanolamine, triethanolamine, sodium taurine, sodium N-methyltaurine, and the like.

  n represents an integer of 1 to 3.

  As the component (b), a compound in which a represents —O— in the above general formula (I), that is, as a long-chain acyl isethionate type anionic surfactant, cocoyl isethionate, stearoyl isethionate , Lauryl isethionate, myristoyl isethionate and the like.

  In the above general formula (I), a compound in which a represents —NH—, ie, a long-chain acyl taurine salt type anionic surfactant includes N-lauroyl taurine salt, N-cocoyl-N-ethanol taurine salt, N -Myristoyl taurine salt, N-stearoyl taurine salt and the like are exemplified.

In the above general formula (I), a compound in which a represents —N (CH ₃ ) —, that is, a long-chain acylmethyl taurate salt type anionic surfactant includes N-lauroyl-N-methyl taurate, N— Examples include palmitoyl-N-methyltaurine salt, N-stearoyl-N-methyltaurine salt, N-cocoyl-N-methyltaurine salt and the like.

  Among these, N-stearoyl-N-methyltaurine salt is particularly preferable as the component (b). (B) A component can use 1 type (s) or 2 or more types.

  When a nonionic surfactant used in a conventional oil-in-water emulsion type cream base is blended as the surfactant, as shown in Comparative Examples 3 and 4 (Table 1), The α gel produced by the ionic surfactant and the higher alcohol cannot obtain the viscosity stability in the presence of polar oil, and the melting point of the α gel also changes, so that the effect of the present invention cannot be obtained.

  The blending ratio (molar ratio) of the component (a) and component (b) in the present invention will be described later.

  The polar oil as the component (c) in the present invention has a molecular weight of 400 or less and an organic value / inorganic value ratio (IOB value) of 0.1 or more, such as cosmetics, pharmaceuticals, quasi drugs and the like. There is no particular limitation as long as it can be used in the field. For example, octanoic acid esters such as cetyl octanoate, isooctanoic acid esters such as cetyl isooctanoate, lauric acid esters such as hexyl laurate, myristic acid esters such as isopropyl myristate, palmitic acid esters such as octyl palmitate and isopropyl palmitate , Isostearic acid esters such as isopropyl isostearate, isopalmitic acid esters such as octyl isopalmitate, adipic acid diesters such as diisopropyl adipate and di (2-ethylhexyl) adipate, sebacic acid diesters such as diethyl sebacate, isononanoic acid Examples thereof include isononanoic acid esters such as isononyl and succinic acid diesters such as di-2-ethylhexyl succinate. Among them, isononyl isononanoate, di-2-ethylhexyl succinate, cetyl isooctanoate, cetyl octanoate, di (2-ethylhexyl) adipate, isopropyl palmitate and the like are preferable examples.

  By setting the molecular weight of the component (c) to 400 or less, the spreadability on the skin can be improved. When the molecular weight exceeds 400, there is a concern that the spread on the skin is deteriorated.

  (C) Although it does not specifically limit as a compounding quantity of a component, It is preferable to mix | blend about 5-30 mass% with respect to the composition whole quantity. If it is less than 5% by mass, there is no stickiness, it is difficult to obtain a good feeling of spreading on the skin, and there is a possibility that the usefulness to the skin as a cream cannot be fully exhibited. On the other hand, if it exceeds 30% by mass, there is a concern about destabilization due to coalescence of oil particles and the like, and an oily feeling tends to be obtained.

  In the present invention, it is preferable that the polar oil component having a molecular weight of more than 400 is not substantially contained, and even when blended, it is not desirable to blend more than 1% by mass.

  In the cream composition of the present invention, in the presence of water (component (d)), the component (b) and the component (a) together with the component (a) form a lamellar bimolecular membrane, so-called α-gel. The plastic fluid property of this α-gel is obtained by retaining the oil particles as component (c). The α-gel can be obtained by dissolving the surfactant and higher alcohol at high temperature and cooling after mixing with water, or melting the higher alcohol at high temperature and mixing with surfactant-dissolved water and cooling. White, highly viscous gel.

  That is, in the production of the cream composition of the present invention, specifically, the component (a), the component (b) and the component (c) are dissolved at a high temperature, mixed with the component (d), and then cooled. Although it can be carried out by a method, a method in which the component (b) is added to the component (d) and dissolved, and the component (a) and the component (c) dissolved at a high temperature are added and mixed. It is not limited to.

  The cream composition of the present invention can be stably blended in a wide temperature range from high temperature to low temperature without crystallizing the component (a) even if the component (c) that affects the viscosity stability of the preparation is blended. It is an object of the present invention to provide an oil-in-water emulsified type cream composition that can achieve the above-described properties, has no stickiness, has a good feeling on use, and spreads well on the skin.

  The cream composition of the present invention is an oil-in-water (O / W) emulsion type emulsion composition. Whether the type of emulsification is “oil-in-water (O / W)” can be confirmed by measuring electrical conductivity.

  In the present invention, “cream” is defined as having a viscosity that does not flow even when the bottle is tilted when the composition is filled in a glass bottle. Specifically, it is 8,000 mPa · s (30 ° C.) or more, more preferably 20,000 mPa · s (30 ° C.) or more, with a B-type viscometer (rotor number 3 and rotor rotation speed 12 rpm). Although the upper limit of the viscosity is not particularly limited, it is preferably about 200,000 mPa · s (30 ° C.) or less because it is inferior in terms of usability when it is too high, but it is appropriately determined depending on the dosage form. Can change.

  The cream composition of the present invention exhibits good stability without water separation. This is thought to be due to the following reasons.

  Cream compositions used as cosmetics are required not to change state from a low temperature to a high temperature, and are particularly required to maintain stability on the high temperature side. The α gel constituting the present invention has a melting point, and the viscosity is lowered at a temperature equal to or higher than the melting point, and when stored for a long period of time, components having different specific gravities are finally completely separated. The fact that the melting point of α-gel varies depending on the type of higher alcohol and the molar ratio of higher alcohol to surfactant is described in Shoji Fukushima, “Physical Chemistry of Cetyl Alcohol” (Fragrance Journal, 1992). Yes.

  That is, an α gel formed from a higher alcohol, a surfactant, and water usually exhibits a single melting point of the higher alcohol and the surfactant that are constituent components thereof. When the higher alcohol / surfactant ratio is small, the melting point of the α gel gradually changes to higher temperatures as the higher alcohol ratio increases, and when the higher alcohol / surfactant ratio reaches 3: 1, the melting point does not change. It is known.

  From this knowledge, the desirable molar ratio of the component (a) to the component (b) in the cream composition of the present invention is 3: 1 or more, that is, the molar ratio of (a) / (b) is 3 or more, more preferably It is 4 or more, particularly preferably 4 to 10. When the molar ratio is less than 3, the melting point of the α gel is not sufficiently increased and the high temperature stability is not sufficient. On the other hand, if the molar ratio exceeds 10, coexisting higher alcohol crystals grow and the α-gel may become unstable, which is not desirable.

  The cream composition of this invention can mix | blend the various components normally used for cosmetics in the range which does not impair the effect of this invention. Examples of these components include monohydric alcohols, polyhydric alcohols, water-soluble polymers, sequestering agents, antioxidants, fragrances, pigments, powders, non-polar oils, silicone oils, and the like. It is not limited.

  In addition, conventionally used surfactants such as nonionic surfactants may be blended in the cream composition of the present invention as long as the effects of the present invention are not impaired, but the blending amount is 0.3 mass. %, And it is preferable that a surfactant other than the component (b), particularly a nonionic surfactant, is not substantially contained.

  The cream composition of the present invention is a moisturizing cream, massage cream, cleansing cream, skin care cosmetics such as essence, hair care cosmetics such as hair cream, body care cosmetics such as sunscreen and body cream, rinses such as gel foundation, etc. It can be used for all possible cosmetics such as cleaning agents.

  EXAMPLES Hereinafter, although this invention is demonstrated further in detail based on an Example, this invention is not limited to a following example. In addition, all compounding quantities are shown by the mass%. Moreover, in Tables 1-5, (a) component / (b) component (molar ratio) was shown by the value rounded off after the decimal point.

<Sample and preparation method used in this example>
1. Sample (surfactant)
N-stearoyl-N-methyltaurine sodium (component of the present invention (b)) and nonionic surfactant polyoxyethylene (20 mol) behenyl ether or polyoxyethylene (60 mol) glyceryl isostearate as a comparative sample Was used.
(Higher alcohol)
Behenyl alcohol and stearyl alcohol were used.

2. Preparation Method Each of the water-soluble component and the oil-soluble component was dissolved and mixed at 90 ° C., mixed at 9000 rpm for 1 minute with a homomixer, and then cooled (30 ° C.) using an ice bath to form an α gel.

<Test method and evaluation method used in this example>
[viscosity]
The viscosity at 30 ° C. was measured using a B-type viscometer (rotor number 3 and rotor rotation speed 12 rpm).

[Stability test]
Using samples obtained in Examples and Comparative Examples, viscosity change after storage at 50 ° C. for 1 month (B-type viscometer, 30 ° C.),
<Stability evaluation criteria>
(Viscosity change after storage at 50 ° C for 1 month)
A: The value obtained by dividing the viscosity of the sample after storage by the viscosity of the sample immediately after preparation is 0.9 or more and less than 1.1. ○: The value obtained by dividing the viscosity of the sample after storage by the viscosity of the sample immediately after preparation. Is 0.7 or more and less than 0.9, or 1.1 or more and less than 1.3. Δ: The value obtained by dividing the viscosity of the sample after storage by the viscosity of the sample immediately after preparation is 0.5 or more and less than 0.7. Or 1.3 or more and less than 1.5 ×: The value obtained by dividing the viscosity of the sample after storage by the viscosity of the sample immediately after preparation is less than 0.5 or 1.5 or more

[Feel of use (no stickiness)]
An actual use test (applied to the face) was conducted by 10 professional panelists and evaluated according to the following evaluation criteria.
<Evaluation criteria for feel of use (no stickiness)>
○: 5 or more out of 10 responded that there was no stickiness △: 3 to 4 out of 10 responded that there was no stickiness ×: 2 or less out of 10 responded that there was no stickiness

[Feel of use (goodness)]
An actual use test (applied to the face) was conducted by 10 professional panelists and evaluated according to the following evaluation criteria.
<Evaluation criteria for feel in use>
○: 5 or more out of 10 responded that the spread on the skin was good. △: 3-4 out of 10 responded that the spread on the skin was good. ×: 2 or less out of 10 persons answered Answers good on skin

(Example 1, Comparative Examples 1-6)
Samples having the compositions shown in Table 1 below were prepared. Using the obtained sample, according to the above evaluation method and evaluation criteria, the viscosity immediately after production (30 ° C.) and high-temperature stability (50 ° C., 1 month), feeling of use (no stickiness, on the skin) Evaluation of goodness of spread. The results are shown in Table 1.

  As is apparent from the results in Table 1, Example 1 having the constituent elements of the present invention is very good in both stability and feel. Since Comparative Example 1 does not contain the component (c), the spread on the skin is poor. Since Comparative Example 2 does not contain the component (a) and contains a higher alcohol having an average alkyl chain length of 16, the stability is poor. Since Comparative Examples 3 and 4 do not contain the component (b) and a nonionic surfactant is blended, both stability and feeling in use are bad. Although the comparative example 5 contains the component (c), since the polar oil component having a molecular weight of more than 400 is highly blended, the spread on the skin is inferior to that of the first embodiment. In Comparative Example 6, since the molar ratio of the component (a) / the component (b) is less than 3, and the viscosity of the system is 6,000, the stability at high temperature is poor.

(Examples 2-3)
Samples having the compositions shown in Table 2 below were prepared. Using the obtained sample, according to the above evaluation method and evaluation criteria, the viscosity immediately after production (30 ° C.) and high-temperature stability (50 ° C., 1 month), feeling of use (no stickiness, on the skin) Evaluation of goodness of spread. The results are shown in Table 2.

  As is apparent from the results in Table 2, in Example 2, the molar ratio of component (a) / component (b) was 10/1, and the stability was very good. In Example 3, the molar ratio of component (a) / component (b) was 15/1, and the stability was good although it did not reach Example 2.

(Examples 4 to 6)
Samples having the compositions shown in Table 3 below were prepared. Using the obtained sample, according to the above evaluation method and evaluation criteria, the viscosity immediately after production (30 ° C.) and high-temperature stability (50 ° C., 1 month), feeling of use (no stickiness, on the skin) Evaluation of goodness of spread. The results are shown in Table 3.

  As is clear from the results shown in Table 3, Example 4 was very good in use because it contained 15% by mass of component (c). In Example 5, the compounding amount of the component (c) was 3% by mass, and although the elongation on the skin did not reach that of Example 4, the usability was good. In Example 6, the blending amount of component (c) was 40% by mass, and although the feeling of stickiness did not reach that of Example 4, the usability was good.

(Examples 7 to 9)
Samples having the compositions shown in Table 4 below were prepared. Using the obtained sample, according to the above evaluation method and evaluation criteria, the viscosity immediately after production (30 ° C.) and high-temperature stability (50 ° C., 1 month), feeling of use (no stickiness, on the skin) Evaluation of goodness of spread. The results are shown in Table 4.

  As apparent from the results in Table 4, Example 7 was very good in stability because it contained two types of component (a). Since Examples 8 and 9 contained only one type of component (a), the stability was good although it did not reach Example 7.

(Examples 10 to 11)
Samples having the compositions shown in Table 5 below were prepared. Using the obtained sample, according to the above evaluation method and evaluation criteria, the viscosity immediately after production (30 ° C.) and high-temperature stability (50 ° C., 1 month), feeling of use (no stickiness, on the skin) Evaluation of goodness of spread. The results are shown in Table 5.

  As is apparent from the results in Table 5, Example 10 was very good to use because it contained no nonionic active agent. In Example 11, 0.5% by mass of the nonionic activator was blended, so that the usability did not reach that in Example 10, but it was good.

Claims (8)

The following components (a) to (d) are included, the compounding ratio (molar ratio) of the component (a) to the component (b) is 3 or more, and the viscosity of the system is 8,000 mPa · s (B-type viscometer, 30 ° C. ) Ri der above, when a polar oil having a molecular weight over 400, der Ru cream composition the amount thereof is less than 1 wt%.
Component (a): One or more higher alcohols selected from stearyl alcohol, batyl alcohol, and behenyl alcohol.
(B) Component: A long-chain acyl sulfonate type anionic surfactant represented by the following general formula (I).
_{R 1 CO-a- (CH 2} ) n SO 3 M 1 (I)
[In the formula (I), R ₁ CO— represents a saturated or unsaturated fatty acid residue (acyl group) having an average carbon number of 10 to 22; a represents —O— or —NR ₂ — (where R ₂ Represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms); M ₁ represents a hydrogen atom, an alkali metal, an alkaline earth metal, ammonium or an organic amine; n represents 1 to 3 Indicates an integer. ]
(C) Component: One or two or more polar oils having a molecular weight of 400 or less selected from octanoic acid ester, isooctanoic acid ester, palmitic acid ester, adipic acid diester, isononanoic acid ester, and succinic acid diester .
(D) Component: Water.   The cream composition of Claim 1 whose compounding ratio (molar ratio) of (a) component with respect to (b) component is 4-10.   (C) Cream composition of any one of Claims 1-2 which contains 5-30 mass% of components in composition whole quantity.   The cream composition according to any one of claims 1 to 3, wherein the component (b) is N-stearoyl-N-methyltaurine salt.   The cream composition according to any one of claims 1 to 4, wherein the component (a) comprises two or more higher alcohols.   The cream composition according to any one of claims 1 to 5, wherein the nonionic surfactant is not blended in an amount exceeding 0.3% by mass in the total amount of the composition.   The cream composition according to any one of claims 1 to 6, which is substantially free of polar oil having a molecular weight of more than 400.   The cream composition according to any one of claims 1 to 7, which is a cosmetic.