JP5172300B2 - Non-contact fungicide composition - Google Patents

Description

  The present invention relates to a non-contact type fungicide composition and a package thereof.

  Generally, clothes are used in a cycle of “wear → washing → storage” after purchase, but it is important to protect (care) from troubles such as mold and odor that are anxious during storage. . Conventional antifungal agents are powders or crystals such as methyl paraoxybenzoate, ethyl paraoxybenzoate, benzoic acid, sodium benzoate, orthophenylphenol, or liquids such as 2-phenoxyethanol and benzalkonium chloride, In either case, the mold-proof performance cannot be sufficiently imparted unless the mold is brought into contact with the article to be protected.

On the other hand, although the technique regarding a non-contact type antifungal agent is disclosed, the antifungal performance is not sufficient. Patent Document 1 discloses a technique related to an antibacterial / antifungal agent for closed spaces. Patent Document 2 describes a technique relating to a water-soluble composition for deodorization and / or sterilization and a method for treating an object using the same. Patent Document 3 describes a technique related to a fungicide composition. Patent Document 4 discloses a technique related to a wood preservative.
JP 2003-286114 A JP 2002-369873 A JP 2003-12411 A JP 2002-337109 A

  Patent Document 1 describes an antibacterial / antifungal agent for closed spaces containing an odorless or slightly odorizable vaporizing antibacterial / antifungal component, and the closed space here is a washing tub of a washing machine, It is a storage box under a clog box and sink, and the effect on clothes stored in a closet or closet is not sufficient. Patent Document 2 describes a technique related to deodorization and sterilization using a water-soluble composition containing a lower alcohol or the like, but it needs to be applied as an aerosol or using a hand spray to exert its effect. . Patent Document 3 describes a technique relating to an antifungal agent containing an acylated glycerol mixture or a fragrance, but in order to exert its effect, it is necessary to spray directly using a trigger type sprayer or an aerosol type sprayer. . Patent Document 4 describes a technique related to a wood preservative having an ant-repellent effect by a branched alcohol, but it is applied directly to wood in order to exert an anti-feeding action, repellent action, insecticidal action, etc. of wood pests. There is a need.

  Therefore, an object of the present invention is to provide a non-contact type anti-fungal agent composition that can exhibit excellent anti-mold performance without being brought into direct contact with the article to be protected, and is particularly suitable for use in a space containing clothing. Is to provide.

  The present inventors have found that an alcohol compound having a specific branched chain has an excellent antifungal performance even when it is not in contact with an article to be protected such as clothing.

  That is, the present invention relates to a non-contact type fungicide composition containing a compound represented by the following general formula (1) (hereinafter referred to as compound (1)), as well as this non-contact type fungicide composition in a container. An antifungal composition package is provided that is housed in a container.

R ¹ —CH ₂ OH (1)
[In formula, R < ¹ > shows a C5-C10 branched saturated aliphatic hydrocarbon group. ]

  The non-contact type anti-fungal agent composition of the present invention and its package are capable of exhibiting an excellent anti-fungal function in a wide range without being in contact with the article to be protected, and particularly clothes that are stored in closets, closets, etc. Excellent anti-fungal performance.

In the compound (1) used in the present invention, R ¹ is a branched saturated aliphatic hydrocarbon group having 5 to 10 carbon atoms, preferably a branched saturated aliphatic hydrocarbon group having 6 to 10 carbon atoms, A branched saturated aliphatic hydrocarbon group having 7 to 10 carbon atoms is more preferable, and a branched saturated aliphatic hydrocarbon group having 8 to 10 carbon atoms is still more preferable. Specific examples of R ¹ include CH ₃ CH (CH ₃ ) — (CH ₂ ) _a — (a is an integer of 2 to 7), CH ₃ (CH ₂ ) _b CH (CH ₃ ) — (b is 2 to 2). 7 an _{integer), CH 3 (CH 2)} c CH (C 2 H 5) - (c is an integer of 1 to _{6), CH 3 (CH 2)} d CH (CH 3) - (CH 2) e - ( d is 1-6, e is an integer of 1 to 6, d + e = 2~7), CH 3 CH (CH 3) - (CH 2) f CH (CH 3) - (f is an integer of from 1 to 5), CH ₃ CH (CH ₃ ) — (CH ₂ ) _g CH (CH ₃ ) — (CH ₂ ) _h — (g is an integer of 1 to 4, h is an integer of 1 to 4, g + h = 2 to 5), CH ₃ (CH ₂ ) _i CH (CH ₃ )-(CH ₂ ) _j CH (CH ₃ )-(i is an integer of 1 to 4, j is an integer of 1 to 4, i + j = 2 to 5), CH ₃ ( CH ₂ ) _k CH (CH ₃ )-(CH ₂ ) _l CH (CH ₃ )-(CH ₂ ) _m — (K is an integer of 1 to 3, l is an integer of 1 to 3, m is an integer of 1 to 3, k + l + m = 3~5 ), CH 3 CH (CH 3) CH (CH 3) - (CH 2) n - (n is an integer of from 1 to _{5), CH 3 CH (CH 3} ) CH (CH 3) - (CH 2) p CH (CH 3) - (p is an integer of 1 to 3), CH ₃ CH (CH ₃ ) CH (CH ₃ )-(CH ₂ ) _q CH (CH ₃ )-(CH ₂ ) _r — (q is an integer of 1 to 2, r is an integer of 1 to 2, q + r = 2 to 3) And the like.

  Specific examples of the compound (1) include, for example, isohexanol, isoheptanol, isooctanol, isononanol, isodecanol, isoundecanol, 2-methylpentanol, 2-methylhexanol, 2-methylheptanol, 2- Examples include methyl octanol, 2-methyl nonanol, 2-methyl decanol, 2-ethyl butanol, 2-ethyl pentanol, 2-ethyl hexanol, 2-ethyl heptanol, 2-ethyl octanol, 2-ethyl nonanol and the like. It is done.

  Among these, from the viewpoint of antifungal effect, isoheptanol, isooctanol, isononanol, isodecanol, isoundecanol, 2-methylhexanol, 2-methylheptanol, 2-methyloctanol, 2-methylnonanol, 2-Methyldecanol, 2-ethylpentanol, 2-ethylhexanol, 2-ethylheptanol, 2-ethyloctanol, 2-ethylnonanol are preferred, isooctanol, isononanol, isodecanol, isoundecanol, 2- More preferred are methylheptanol, 2-methyloctanol, 2-methylnonanol, 2-methyldecanol, 2-ethylhexanol, 2-ethylheptanol, 2-ethyloctanol, 2-ethylnonanol, isononanol, isodecano Le, iso undecanol, 2-methyl-octanol, 2-methyl nonanol, 2-methyl decanol, 2-ethyl heptanol, 2-ethyl octanol, 2-ethyl nonanol is more preferable.

  Compound (1) can be used alone or in combination of two or more.

  The non-contact type fungicide composition of the present invention contains the compound (1) as a main component, and the form thereof may be any form such as gel, powder, granule, and liquid.

  Although content of the compound (1) in the non-contact-type antifungal agent composition of this invention can be suitably adjusted with the kind and usage pattern, 0.1-100 mass% is preferable normally, and 1-100 The mass% is more preferable.

  When the non-contact type fungicide composition of the present invention is gelled, it is common to use a gelling agent. The gelling agent is not particularly limited. For example, polyvinyl alcohol, polyethylene glycol, polyvinyl pyrrolidone, alginic acid, cellulose, starch, etc., or derivatives or salts thereof formed from water-soluble organic polymers such as vinyl acetate Resin emulsions, synthetic resin emulsions such as vinyl acetate and vinyl chloride copolymer resin emulsions, water soluble emulsions such as rubber latex, carrageenan, agar, gelatin, pectin and other animals, plants, algae, and microorganisms Examples thereof include gelling agents derived from natural products to be extracted.

  Although content of the compound (1) in a gel-like non-contact-type antifungal agent composition can be suitably adjusted with the kind and usage form, 0.1-60 mass% is preferable normally, and 1-50 The mass% is more preferable.

  In order to disperse and emulsify the compound (1) in the gel-like non-contact type fungicide composition, it is preferable to use a surfactant. There is no restriction | limiting in particular as surfactant, At least 1 sort (s) chosen from a nonionic surfactant, a cationic surfactant, an anionic surfactant, and an amphoteric surfactant can be used. .

  Nonionic surfactants include polyoxyalkylene alkyl or alkenyl ether, polyoxyalkylene alkyl phenyl ether, polyoxyalkylene fatty acid ester, polyoxyalkylene sorbitan fatty acid ester or polyoxyalkylene glycerin fatty acid ester, polyoxyalkylene sorbit fatty acid ester , Polyoxyalkylene castor oil or hydrogenated castor oil, alkyl or alkenyl diethanolamide, alkylamine or alkyldimethylamine, alkenylamine or alkenyldimethylamine, polyoxyalkylenealkyl or alkenylamine and the like.

  Examples of the cationic surfactant include primary amine salts, secondary amine salts, tertiary amine salts, and quaternary ammonium salts.

  Anionic surfactants include alkyl benzene sulfonates, alkyl sulfates or alkenyl sulfates, olefin sulfonates, alkane sulfonates, salts of alkyl polyhydric alcohol ether sulfonates such as alkyl glyceryl ether sulfonates, Examples include higher fatty acid salts, alkyl or alkenyl ether sulfates, alkyl or alkenyl ether carboxylates, and the like.

  Amphoteric surfactants include alkyl or alkenylamine oxide, amidopropylamine oxide (obtained by reacting amide compound of lauric acid and dimethylaminopropylamine with hydrogen peroxide, etc.), dimethyllaurylamine oxide, dimethylamino Examples include betaine acetate, imidazolinium betaine, fatty acid amidopropyldimethylaminoacetic acid betaine, N-acylamino acid or a salt thereof, and N-acylmethyltaurate.

  When the non-contact fungicide composition of the present invention is powdered or granular, as a powder or granular carrier, silica gel, zeolite, calcium silicate, diatomaceous earth, alumina, allophane, vermiculite, perlite, shirasu balloon, sepiolite, Inorganic porous carriers such as kaolin, hydrotalcite, talc, snow tech and bentonite, and organic porous carriers such as activated carbon, pulp, fiber material and synthetic resin can be used.

  The content of the compound (1) in the powdery or granular non-contact type antifungal agent composition can be appropriately adjusted depending on the type and use form, but is usually preferably 0.1 to 70% by mass. -60 mass% is more preferable.

  When the non-contact type fungicide composition of the present invention is made liquid, the above-mentioned surfactant or a solvent such as alcohol can be used as a solubilizer. The liquid composition can be used by a conventionally known method such as a method of soaking in a core rod, filter paper, nonwoven fabric or the like and volatilizing using a permeable membrane.

  The content of the compound (1) in the liquid non-contact fungicide composition can be appropriately adjusted depending on the type and use form, but is usually 0.1 to 40% by mass, preferably 1 to 30% by mass. % Is more preferable.

  The non-contact type anti-fungal agent composition of the present invention can be added to various solvents, oils, sodium sulfate, sodium sulfate, N, N, Other components such as a salt such as N-trimethylglycine, a pH adjuster, an antioxidant, an antiseptic, a bactericidal / antibacterial agent, a deodorant, a fragrance, a dye, and an ultraviolet absorber can be contained.

  The non-contact type fungicide composition of the present invention can be provided as a fungicide composition package in a container. The non-contact type fungicide composition of the present invention is air permeable as it is or dissolved in a volatile solvent such as alcohol and remains in a liquid state or in the form of gel, powder, granule or the like. Place in a container. Examples of the breathable container include a bag-like product made of a laminate composed of a breathable thermoplastic resin on the inner surface and a breathable support on the outer surface. For example, a nonwoven fabric is used as the breathable support. And a bag made of laminated paper made by laminating a breathable thermoplastic resin film such as a polyethylene film.

  The non-contact fungicide composition of the present invention and its package can be installed in, for example, a closet, a closet, a shoe box, etc. to prevent the occurrence of mold on clothes, shoes, wall surfaces, floor surfaces, etc. In particular, it is suitable for use in a space storing clothes such as a closet and a closet to prevent generation of mold on the clothes.

Examples 1-5 and Comparative Examples 1-5
Using the following blending components, a non-contact type fungicide composition having the blending formulation shown in Table 1 was prepared. About the obtained non-contact-type antifungal agent composition, antifungal performance was evaluated by the following method. The results are shown in Table 1.

<Blending ingredients>
Compound (1)
a-1: isoheptanol a-2: isooctanol a-3: isononanol a-4: isodecanol a-5: isoundecanol a-6: 2-ethylhexanol Comparison product a′-1 of compound (1) : 2-methylpropanol a'-2: 2-heptanol a'-3: isotridecanol a'-4: 1-hexanol a'-5: 1-dodecanol <Antifungal performance evaluation method>
(1) Preparation of Test Bacteria Aspergillus.niger and Cladosporium spores and mycelia grown on potato dextrose agar (manufactured by Wako Pure Chemical Industries, Ltd.) were dispersed in a sterilized 0.05% Tween80 (Rheodor TW-0120) aqueous solution. A mold suspension of × 10 ⁶ to 1 × 10 ⁷ cells / mL was prepared.

(2) Preparation of mold test piece Cotton melias cloth cut to 3 cm x 3 cm and black dyed cotton broad cloth were sterilized (autoclave: 2 atm (202650 Pa), 125 ° C / 15 min), and 90 mm plastic as shown in Fig. 1 Two pieces each were allowed to stand on Petri dish 1 (Nissui Pharmaceutical, Nissui A Petri dish, sterilized shallow mold). 200 μL of a 2.4% potato dextrose broth aqueous solution (manufactured by Wako Pure Chemical Industries, Ltd.) sterilized on each test cloth was applied, and 100 μL of the above mold suspension was applied as a mold test piece 2, 2 ′.

(3) Mold prevention test A cloth 4 (cotton Melias cloth, 1.5 cm × 1.5 cm) impregnated with the non-contact type mold prevention agent composition described in Table 1 was applied to the center of the lid 3 of the petri dish at 25 ° C. After culturing at 100% RH for 7 days, the growth state of the mold was visually observed and evaluated based on the following five-stage criteria. Among them, those with a rating of-and + suppress the growth of mold, and the antifungal effect can be recognized remarkably. In addition, when the growth state of mold | fungi was observed similarly without sticking the cloth which impregnated the non-contact-type antifungal agent composition on the petri dish lid | cover, it confirmed that the antifungal effect was not recognized. The results are shown in Table 1.
-: No mold growth +: Only mildew mycelium grows slightly ++: Only mildew mycelium grows +++: In addition to mold mycelium, mildew spores grow slightly +++++: Both mold spores and mycelia are sufficient Growing in

  From Table 1, the compositions of Comparative Examples 1 to 5 have insufficient antifungal performance against Aspergillus.niger or Cladosporium, whereas the non-contact antifungal compositions of Examples 1 to 5, Aspergillus.niger It can be seen that the antifungal performance is high with respect to both Cladosporium and Cladosporium.

Example 6
A non-contact type anti-fungal agent was impregnated in a non-woven fabric (Toyobo Co., Ltd., Toyobo Spunbond, Borans 4301N) with 150% by mass of the non-contact anti-fungal composition of the formulation shown in Example 1 of Table 1. A composition-impregnated nonwoven fabric was prepared. In the plastic storage box (64 cm × 40 cm × 23 cm, made by Yoshikawa, Neo Tenor Middle M23) having an internal volume of about 60 L, 1.7 g of the non-contact type fungicide composition-impregnated nonwoven fabric and the same mold test as in Example 1 The pieces 2 and 2 'were left standing with the petri dish 1 removed. The mold was cultured at 25 ° C. and 100% RH for 7 days, and the antifungal effect was determined in the same manner as in Example 1. As a result, the determination was “−” for both Aspergillus.niger and Cladosporium, and the mold prevention performance was high.

In an Example, it is the schematic of the petri dish used for evaluation of mold prevention performance.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Petri dish 2,2 'Mold test piece 3 Petri dish cover 4 Cloth impregnated with non-contact type fungicide composition

Claims (3)

A liquid non-contact fungicide composition containing at least one compound selected from isoheptanol, isooctanol, isononanol, isodecanol, and 2-ethylhexanol, and used by being volatilized in a space containing clothing . The liquid non-contact type fungicide composition according to claim 1 , wherein the compound is infiltrated into a core rod, filter paper, non-woven fabric, or Melias cloth and volatilized . An antifungal composition package comprising the liquid non-contact type antifungal composition according to claim 1 housed in a container.

Images