JP5340352B2 - Syringe pump inspection and calibration machine - Google Patents

Description

  The present invention relates to an inspection / calibration device for a syringe pump, and more particularly to an inspection / calibration device suitable for checking whether the housing side of a syringe pump operates correctly or as a closing adjustment jig.

  Syringe pumps are widely used for applications in which a drug solution or nutrient is delivered to a patient accurately and over a long period of time. This syringe pump is configured such that a syringe is set in a housing, and a chemical solution stored in a main body case of the syringe is pushed out by a slide of a pusher.

Thus, when a malfunction occurs in the syringe pump, it is related to the life of the patient, so that it is regularly checked for proper operation.
The main items of inspection are as follows.
(1) Has the outer cylinder of the syringe been confirmed to be properly clamped?
(2) Is the size of the syringe being measured?
(3) Have you confirmed that the syringe pusher is properly clamped?
(4) Is the liquid delivered accurately with the set liquid delivery amount?
(5) Is the warning operation properly performed when the liquid supply path is blocked?

The inspection items (1) to (3) can be confirmed by actually setting the syringe in the housing and checking whether a predetermined display is made on the display portion of the housing and whether the pusher is operated.
However, for the inspection item (4), the syringe filled with water is set in the housing, the syringe pump is operated, the water delivered from the syringe is taken into a measuring cylinder and weighed, and the actual liquid supply amount is determined in advance. It is confirmed whether it matches with the set liquid supply amount.
As for the inspection item (5), a device that applies the same force as when the liquid supply path is blocked to the syringe side pusher, for example, a spring-like device is attached, and the housing side performs a warning operation. I have confirmed.

JP 2010-88564 A

As for the inspection item (4), it is not easy to accurately read the scale of the measuring cylinder, and skill is required. In addition, a certain amount of water is required to perform measurement with the graduated cylinder, and therefore the syringe pump must be driven for a considerable time.
In addition, for the inspection item (5), it is necessary to prepare a dedicated product. By implementing both the inspection item (4) and the inspection item (5), the number of items for inspection items increases.
Furthermore, since the blockage detection plate changes with time, it is necessary to periodically perform calibration for detecting the closed pressure, but it is also necessary to prepare a dedicated product called a blockage adjustment jig for this calibration.

  The present invention has been made paying attention to the above-mentioned conventional problems, and the inspection items (1) to (5) including the inspection items (4) and (5) and the calibration described above are combined into one. It is an object of the present invention to provide a novel and useful syringe pump inspection and calibration machine that can be performed easily and accurately with an apparatus.

SUMMARY OF THE INVENTION The present invention has been made to solve the above-mentioned problems, and the invention according to claim 1 includes a guide part formed in a cylindrical shape imitating an outer cylinder of a syringe, and an axial tip part of the guide part. A cylindrical detection unit that is provided continuously and communicates with the guide unit, a fixed slit plate provided on an inner surface of the detection unit, a presser that is incorporated in the guide unit so as to be axially movable, and the presser A moving slit plate that is fixed to an axial tip of the moving member and moves in a state of facing the solid slit plate following the movement of the pusher, and is accommodated in the guide portion, and is attached to the pusher. It has a closing spring that restricts movement in the axial direction by contact, a computer unit, and a display unit provided in the computer unit, and has a rod shape as a whole, and is set in the housing instead of a syringe. Check and calibrate the housing side When the housing pump is inspected and calibrated in place of the syringe and operated, the computer unit uses the translucency of the two slits that change with time to move the pusher. calculates a check calibration machine syringe pump, characterized in that to be displayed on said display means an operating state of the housing on the basis of the result.

  According to a second aspect of the present invention, in the syringe pump inspection / calibration machine according to the first aspect, the computer unit is configured to feed and block the corresponding syringe from the movement distance of the pusher during non-regulation and regulation by the closure spring. An inspection / calibration machine for a syringe pump, characterized by deriving pressure.

  According to a third aspect of the present invention, in the syringe pump inspection / calibration machine according to the first or second aspect, the fixed slit plate or the movable slit plate is provided with two or more rows of slit groups whose slit positions are shifted along the moving direction. This is a syringe pump inspection and calibration machine.

  According to a fourth aspect of the present invention, there is provided the syringe pump inspection and calibration machine according to any one of the first to third aspects, wherein the computer unit includes a communication unit for communication with an external host computer. It is an inspection and calibration machine.

If the inspection / calibration machine for syringe pumps of the present invention is used, the following inspection items can be easily and accurately confirmed with a single device.
(1) Has the outer cylinder of the syringe been confirmed to be properly clamped?
(2) Is the size of the syringe being measured?
(3) Have you confirmed that the syringe pusher is properly clamped?
(4) Is the liquid delivered accurately with the set liquid delivery amount?
(5) Is the warning operation properly performed when the liquid supply path is blocked?
In addition, the occlusion detection can be calibrated.

It is a perspective view which shows the state which set the inspection calibration machine of the syringe pump which concerns on embodiment of this invention to the housing. It is a perspective view of the inspection / calibration machine of FIG. It is a partial cross section top view of the inspection / calibration machine of FIG. It is a partial cross section side view of the inspection / calibration machine of FIG. FIG. 3 is a layout view of two slit plates of the inspection / calibration machine of FIG. 2. FIG. 6 is a superimposed view of the two slit plates of FIG. 5. It is an electrical block diagram centering on the computer part of the inspection / calibration machine of FIG. It is a partial cross section side view which shows the state just before the start of regulation by the closure spring at the time of the action | operation of the inspection / calibration machine of FIG. It is a partial cross section side view which shows the state after the regulation start by the closure spring at the time of the action | operation of the inspection / calibration machine of FIG.

A syringe pump inspection and calibration machine 1 according to an embodiment of the present invention will be described with reference to the drawings.
As shown in FIGS. 1 and 2, in the inspection / calibration machine 1, a guide unit 3, a pusher 13, a detection unit 31, and a computer unit 47 are integrated. In the inspection / calibration machine 1, the guide unit 3, the detection unit 31, and the computer unit 47 are connected in a straight line, and are formed in a rod shape as a whole.
In the inspection / calibration machine 1, the outer surface of the guide portion 3 and the proximal end portion of the pusher 13 are provided with external shapes simulating a syringe so that they can be set in the housing 101 instead of the syringe of the syringe pump, and the axial direction is horizontal. In this state, when the guide unit 3 is placed on the syringe placement unit 103, clamped by the rotation lever 105, and the presser 13 is fixed to the slider 107, the housing 101 side is inspected in the same manner as when the pseudo syringe is set. The calibrator 1 can be driven.

The configuration will be described in detail with reference to FIGS.
The guide portion 3 of the inspection / calibration machine 1 has a cylindrical shape, and the distal end portion and the proximal end portion in the axial direction are open. A step 5 for narrowing the passage is provided on the inner surface on the tip side. Further, the base end side is closed with a mounting plate 7, and the outer edge of the mounting plate 7 extends outward to correspond to the outer cylinder flange of the pseudo syringe. A through hole is formed in the center of the mounting plate 7, and a guide cylinder 11 is attached to surround the through hole. The hollow portion of the guide cylinder 11 and the internal space of the guide part 3 communicate with each other through the through hole. doing.

A pusher 13 is incorporated in the guide portion 3 having the above-described configuration.
A plate 17 is fixed to the base end portion of the shaft 15 of the pusher 13, and the plate 17 is fixed to the slider 107 of the housing 101. A cylindrical joint 19 is attached to the tip of the shaft 15. The joint 19 is provided with two steps, and the diameter is reduced toward the traveling direction side. The shaft 15 is inserted through the guide tube 11 and is supported so as to be movable in the axial direction, and the tip portion and the joint 19 enter the internal space of the guide portion 3.

  A load spring (coil spring) 21 is wound around a portion of the shaft 15 protruding from the guide tube 11, and one end of the load spring 21 is fixed to a stopper 23 attached to the outer periphery of the shaft 15. The other end is fixed to the guide tube 11. The shaft 15 is urged by the load spring 21 toward the traveling direction, which is the pushing direction of the chemical solution.

  Reference numeral 25 denotes a closing spring (coil spring), and the closing spring 25 is accommodated in the guide portion 3. The central diameter of the closing spring 25 is set so as not to contact the inner peripheral surface of the guide portion 3, but to overlap the peripheral surface that has been reduced in diameter by the step 5. The closing spring 25 is wound around the joint 19, the rear end on the traveling direction side is fixed to the outer peripheral surface of the step in the middle of the joint 19, and the front end on the traveling direction side is a free end.

  Reference numeral 29 denotes a moving slit plate. The moving slit plate 29 is fixed with its base end side edge inserted into the insertion groove of the joint 19 described above with the rectangular plate surface directed in the vertical direction. The closing spring 25 described above is arranged in a state of surrounding the moving slit plate 29. The closing spring 25 is not in contact with the moving slit plate 29.

The detection unit 31 is connected to the distal end side in the axial direction of the guide unit 3. Similarly to the guide part 3, the detection part 31 has a cylindrical shape, and its outer peripheral surface is flush with the guide part 3. In addition, the internal spaces communicate with each other.
A light receiving element 33 is attached to the upper side of the inner surface of the detection unit 31, and a light emitting element 35 is attached to the lower side so as to face the light receiving element 33. The light emitting element 35 is composed of a light emitting diode.

  Reference numeral 37 denotes a fixed slit plate. The fixed slit plate 37 is supported by being suspended from the inner upper surface of the detection unit 31 with a rectangular plate surface facing the vertical direction. The fixed slit plate 37 is sandwiched between the light receiving element 33 and the light emitting element 35 described above.

The leading end side of the moving slit plate 29 in the advancing direction enters the internal space of the detector 31 and faces the fixed slit plate 37 in a state of facing from below.
As shown in FIG. 4, a slit pattern is formed in each of the moving slit plate 29 and the fixed slit plate 37.

  As shown in FIG. 5, a slit group 39 is formed in the fixed slit plate 37, each slit 41 has a rectangular shape with the same dimension, the short side is parallel to the moving direction indicated by the arrow, and the long side Are aligned in a vertical state, and the spacing between adjacent slits 41 is the same. The spacing dimension (D1) between adjacent slits 41 is also 50 microns. Further, the length dimension of the short side of each slit 41, that is, the width dimension (D2) is 50 microns. The fixed slit plate 37 is formed with two rows of the slit groups 39 described above, and the slit interval is shifted by 25 microns.

A slit group 43 is also formed on the moving slit plate 29, and each slit 45 has a rectangular shape with the short side parallel to the moving direction indicated by the arrow and the long side being vertical. Aligned. The width dimension of each slit 45 and the interval dimension between adjacent slits 45 are set in the same manner as the slit 41. However, the long side of the slit 45 is longer than the short side of the fixed slit plate 37.
In the inspection / calibration machine 1, the light receiving element 33 detects interference fringes generated by passing the light irradiated from the light emitting element 35 through the moving slit plate 29 and the fixed slit plate 37.

The computer unit 47 is connected to the distal end side in the axial direction of the detection unit 31. The computer unit 47 has a box shape, and its outer dimensions are slightly smaller than those of the guide unit 3 and the detection unit 31 described above.
Reference numeral 27 denotes a magnet of the magnet switch 28, and the magnet 27 is attached to the front end of the moving slit plate 29 in the traveling direction. The magnet switch 28 that is turned on when the magnet 27 approaches is provided on the computer unit 47 side. When the tip of the closing spring 25 comes into contact with the step 5 and starts to be restricted in the compression direction, the magnet switch 28 is turned on. Switch 28 is positioned.
As shown in FIG. 7, the computer unit 47 includes a one-chip computer 49. The computer 49 is provided with various memories 51 and a counter 53 for storing various data and procedures and securing a work area.
A display unit 48 is disposed on the surface of the computer unit 47, and the display unit 48 is under display control by a computer 49. In addition, a connector 50 of a communication unit is provided at the tip, and data can be written and changed from an external personal computer via a wired cable.

Various memories 51 of the computer 49 store pseudo syringe data and processing procedures.
The computer 49 follows the movement of the presser 13 and the moving slit plate 29 moves. The computer 49 detects the change in the light / dark pattern of the interference fringes caused by light passing through the moving slit plate 29 and the fixed slit plate 37. The number of changes is detected and calculated as the movement distance of the pusher 13.

When checking the accuracy of the liquid feeding amount, the computer 49 derives the moving speed by dividing the moving distance by the difference in the count number counted by the counter 53. And this moving speed is converted into a liquid feeding amount according to the pseudo syringe. Then, the set liquid supply amount on the housing 101 side is read from the various memories 51, the accuracy of “+ ◯%” and “− ○%” is calculated, and displayed on the display unit 48.
Since the two slit groups 39 of the fixed slit plate 37 are deviated by 25 microns with respect to the moving direction, even if the width of the slit is 50 microns, the speed is obtained with the same effective number of digits as in the case where a slit having a width of 25 microns is provided. A value is obtained.

  When confirming the warning operation of the blocking pressure, the computer 49 confirms that the blocking spring 25 hits the step 5 and has created the blocking pressure by turning on the magnet switch 28, and then from the various memories 51 to the blocking spring 25. Spring characteristic data (calibration curve data) is read out, and the sequentially input moving distance is converted into a load value applied as a contraction of the closing spring 25, and further converted in accordance with the pseudo syringe to calculate the closing pressure. . Then, the value is displayed on the display unit 48. Also, the moving speed is sequentially calculated in the same manner as described above. When it is determined that the moving slit plate 29 has stopped, it is determined whether or not the calculated closing pressure coincides with the closing pressure of the warning action activation on the housing 101 side, and the calculated closing pressure value is simultaneously determined. indicate.

The inspection / calibration machine 1 is configured as described above. Next, an inspection procedure by the inspection / calibration machine 1 will be described.
First, in the various memories 51 of the inspection / calibration machine 1, the liquid supply amount corresponding to the pseudo syringe set on the housing 101 side and the threshold value of the blocking pressure are stored.
Then, as shown in FIG. 1, the inspection / calibration machine 1 is set in the housing 101, and the dial 109 is turned to match the liquid feeding amount set on the computer 49 side. If the set state is OK, the clamp confirmation LED and the slider confirmation LED on the housing 101 side change from the blinking state to the unlit state. Thereby, it can confirm that LED is operate | moving correctly.

Next, the pusher 13 is advanced in the direction of pushing out the chemical solution. Since the slider 107 fixed to the pusher 13 does not operate unless the diameter of the guide portion 3 is measured, it can be confirmed that the measurement function on the housing 101 side works by the advancement of the pusher 13.
When the pusher 13 is moved, the computer 49 performs the processing relating to the liquid feeding amount and the blocking pressure as described above, so that the display unit 48, the display unit 111 on the housing 101 side and the warning lamp 113 are turned on and the alarm is activated. By comparing, it is possible to confirm whether the liquid feeding is accurately performed with the set liquid feeding amount and whether the warning operation is properly performed when the liquid feeding path is blocked.

Next, the calibration procedure for blockage detection will be described.
As in the case of the inspection, as shown in FIG. 1, the inspection / calibration machine 1 is set in the housing 101, and the dial 109 is turned to match the liquid feeding amount set on the computer 49 side. The housing 101 side is set to a blockage detection calibration mode by pressing a predetermined switch.
Then, the pusher 13 is advanced in the direction of pushing out the chemical solution to generate a blocking pressure. When a predetermined blockage pressure (value) is displayed on the display unit 48 of the inspection / calibration machine 1, the pusher 13 is stopped and the blockage pressure (value) is written to the housing 101 side by pressing a predetermined switch. Thereafter, the pusher 13 is advanced again. The above operation is repeated and three occlusion pressures (values) are written.
By this writing, the blockage detection on the housing 101 side is calibrated.

  As described above, if this inspection / calibration machine 1 is used, not only can all necessary items (1) to (5) be easily and accurately inspected, but also occlusion detection can be calibrated.

The embodiment of the present invention has been described in detail above. However, the specific configuration is not limited to this embodiment, and the present invention can be changed even if there is a design change without departing from the gist of the present invention. included.
For example, the display unit 48 may indicate the operation status numerically, or may indicate “OK”, “NO”, or “abnormality occurrence”.

  Since the inspection / calibration machine of the present invention can not only inspect the housing of the syringe pump but also calibrate the clogging detection, if only this is prepared, it can cope with the inspection / calibration.

1 …… Inspection and calibration machine 3 …… Guide part 5 …… Step 7 …… Mounting plate 11 …… Guide cylinder 13 …… Pusher 15 …… Shaft 17 …… Plate 19 …… Joint 21 …… Load spring 23 …… Stopper 25... Closing spring 27... Magnet 28. Magnet switch 29... Moving slit plate 31... Detection unit 33. … Slit 43 …… Slit group 45 …… Slit 47 …… Computer section 48 …… Display section 49 …… Computer 50 …… Connector 51 …… Memory 53 …… Counter D1 …… Spacing between adjacent slits D2 …… Slit Width dimension 101 …… housing 103 …… syringe mounting portion 105 …… rotating lever 107 …… slider 109 …… dial 111 …… table Part 113 ...... warning lamp

Claims (4)

A guide part formed in a cylindrical shape that mimics the outer cylinder of a syringe, a cylindrical detection part that communicates with the guide part in the axial direction, and an inner surface of the detection part. A fixed slit plate provided, a pusher incorporated in the guide portion so as to be movable in the axial direction, and fixed to the tip end portion in the axial direction of the pusher, and following the movement of the pusher, the inside of the detection portion is A moving slit plate that moves in a state of facing the solid slit plate, a closing spring that is accommodated in the guide portion and restricts movement in the axial direction by contact with the pusher, a computer portion, and the computer portion An inspection / calibration machine for a housing pump that has a bar-like shape as a whole, is set in place of a syringe in a housing and inspects and calibrates the housing side,
Actuation is set in place of the syringe to the housing, wherein the computer unit by using the light-transmitting of the two slits time varying calculates the moving distance of the push rod, the housing on the basis of the result An inspection / calibration machine for a syringe pump, characterized in that the operation status of the syringe pump is displayed on the display means. In the syringe pump inspection and calibration machine according to claim 1,
The computer unit is an inspection / calibration machine for a syringe pump, which derives the corresponding liquid feeding amount and blocking pressure from the movement distance of the pusher when not controlled and controlled by the closing spring. In the syringe pump inspection and calibration machine according to claim 1 or 2,
An inspection / calibration machine for a syringe pump, wherein the fixed slit plate or the moving slit plate is provided with two or more rows of slit groups whose slit positions are shifted along the moving direction. In the syringe pump inspection and calibration machine according to any one of claims 1 to 3,
An inspection / calibration machine for a syringe pump, wherein the computer unit includes a communication unit for communication with an external host computer.

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