JP5347691B2 - Blood purification device and heater - Google Patents

Description

  The present invention relates to a blood purification apparatus including a warmer that warms a fluid used for blood purification, and the warmer.

  Conventionally, for example, for patients with renal insufficiency, in order to purify their blood, continuous slow hemofiltration (CHF) and continuous hemodiafiltration (CHDF) have been performed. The treatment used is being performed.

  CHF is blood purified by injecting blood taken from a patient into a blood purifier provided with a semipermeable membrane for filtration (hereinafter referred to as “filtration membrane”) and filtering the blood using a filtration membrane. Is returned to the patient, and waste products (for example, electrolyte substances such as urea and sodium chloride) and the solvent (water) in the blood obtained by filtration are discarded. At the same time, in order to compensate for the decrease in the solvent in the patient's blood, a method of continuously and slowly replenishing the patient's blood with a predetermined replenisher (hereinafter referred to as “replacement”). In CHF, waste products and solvents in blood to be discarded are referred to as filtrate (hereinafter referred to as “filtrate”).

  On the other hand, CHDF is a method for improving small molecule removal ability in CHF, and is a method of performing dialysis treatment in addition to CHF. That is, CHDF also supplies dialysate to the blood purifier and moves waste products still contained in the blood purified by filtration into the dialysate through the dialysis membrane. Remove waste products. Then, the blood purified by filtration and dialysis is returned to the patient and the replacement fluid is replenished to the patient's blood continuously and slowly. In CHDF, waste products and solvents in blood obtained by filtration and used dialysate are referred to as filtrate.

  By the way, when the patient's blood volume changes rapidly, the patient's condition rapidly deteriorates. In order to prevent this, the flow rate of blood drawn from the patient must be balanced with the flow rate of blood returned to the patient and the replacement fluid injected into the patient. For this reason, when performing the above-described blood purification treatment, a blood purification device has been proposed for balancing the flow rate of blood taken from a patient with the flow rate of blood returned to the patient and the flow rate of replacement fluid injected into the patient. (For example, refer to Patent Document 1).

  FIG. 8 is a diagram for explaining a conventional blood purification apparatus.

  As shown in the figure, in the conventional blood purification apparatus 2, three containers 3 each containing a dialysate, a replacement fluid, and a filtrate are suspended from a weight measuring device 4, and the weight of each container 3 is The total weight of the three containers 3 is measured. Thereby, the flow volume of the dialysate and replacement fluid used, and the flow volume of the discarded filtrate can be balanced.

JP 2007-285830 A

  Here, since the dialysate and the replacement fluid are injected into the blood returned to the patient, it is desirable that the dialysate and the replacement fluid be heated to a temperature close to that of the blood.

  For this reason, in the conventional blood purification apparatus, a heater and a heating container are provided downstream of the weight measuring device 4 and the container 3 shown in FIG. 8 to heat the dialysate and the replacement fluid.

  Each container is disposable and needs to be attached for each treatment. In this case, in addition to the operation of attaching the container 3 to the weight measuring device 4, the operation of attaching the heating container to the heater is performed. Since it is necessary, the installation becomes complicated and very troublesome. In addition, a space for attaching a heater to the blood purification device is required.

  Therefore, if the weight measuring device 4 and the warmer can be integrated and the container can be made into one, the mounting work becomes simple, and the warmer can be installed in a small space.

  However, this system has a problem that the dialysate and the replacement fluid stored in the container cannot be efficiently heated. Furthermore, when heating and weight measurement are simultaneously performed in a form that places importance on heating, there is a problem that accurate measurement cannot be performed particularly when a small amount of liquid is measured.

  In other words, since the container containing the dialysate or the replacement fluid is suspended from the weight measuring device, while accurately measuring the weight of the dialysate or the replacement fluid in the container while being suspended, It is difficult to heat the replacement fluid efficiently. This is because, since the container is suspended, the dialysis liquid and the replacement fluid in the container are biased by gravity, particularly when the dialysate and the replacement fluid in the container are small.

  Therefore, the present invention has been made in view of such a problem, and the mounting operation of the container is simple and can be arranged in a space-saving manner, so that the dialysate and the replacement fluid contained in the container can be efficiently used. An object of the present invention is to provide a blood purification device and a warmer that can be warmed up.

  In order to achieve the above object, a blood purification device according to the present invention is a blood purification device comprising a weight measuring device that suspends a container containing a fluid used for blood purification and measures the weight of the fluid. And a heater that is suspended from the weight measuring instrument and that heats the fluid contained in the container, wherein the heater is inclined at a predetermined angle from a vertical direction, and the container is disposed. And a heating surface portion in contact with the container.

  According to this, the container is placed on the warming surface part by the warming surface part being inclined with respect to the vertical direction and the container being in contact with the warming surface part. For this reason, even if the amount of fluid in the container is small, the deviation of the fluid in the container due to gravity can be suppressed, and the fluid can be uniformly heated while accurately measuring the fluid in the container. In addition, since the heater is integrated with the weight measuring instrument, the measuring container and the heating container can be combined into one, making the mounting operation simple and space-saving. is there. Therefore, the mounting operation of the container is simple and can be arranged in a space-saving manner, and the dialysate and the replacement fluid stored in the container can be efficiently heated.

  Preferably, the predetermined angle is 10 to 30 degrees.

  According to this, since the inclination with respect to the vertical direction of a heating surface part is as small as 10-30 degrees, in order to arrange | position a warmer, it is not necessary to ensure a big space. Therefore, the dialysate and the replacement fluid stored in the container can be efficiently heated in a space-saving manner.

  Preferably, the warmer includes a first warming unit that warms the fluid accommodated in the container via the warming surface, and the blood purification device further includes the first warming unit. And a second heating unit that further heats the fluid contained in the container.

  According to this, a container is covered so that it may be pinched | interposed into a 1st heating part and a 2nd heating part, and the fluid accommodated in the container is heated from the both sides of a container. Therefore, the dialysate and the replacement fluid stored in the container can be efficiently heated.

  Preferably, the warmer further includes a heating member that includes the heating surface portion and holds the container, and a slide member that advances and retracts the holding member in the horizontal direction.

  According to this, the holding member holding the container can be moved back and forth in the horizontal direction, and the container can be easily detached from the blood purification apparatus. Therefore, the dialysate and the replacement fluid stored in the container can be efficiently heated while facilitating the detachment of the container.

  Further, the present invention can be realized not only as such a blood purification apparatus but also as a warmer provided in the blood purification apparatus.

  According to the present invention, in a blood purification apparatus and a warmer provided with a heater for heating a fluid used for blood purification, the mounting operation of the container is simple and can be arranged in a space-saving manner, and accommodated in the container It is possible to efficiently warm the dialysate and the replacement fluid. In addition, even a small amount of liquid can be accurately measured.

It is an external view which shows the blood purification apparatus in embodiment of this invention. It is a block block diagram which shows the blood purification apparatus in embodiment of this invention. It is a figure explaining the structure of a heating apparatus in detail. It is a figure explaining the structure of a heating apparatus in detail. It is a figure explaining the inclination of a heating surface part. It is a figure explaining the structure of a slide member. It is a figure explaining that a slide member advances and retracts a 1st holding member. It is a figure which shows the structure of the heating apparatus in the modification of this Embodiment. It is a figure explaining the conventional blood purification apparatus.

  EMBODIMENT OF THE INVENTION Below, the form for implementing this invention is demonstrated with reference to drawings.

  FIG. 1 is an external view showing a blood purification apparatus 1 according to an embodiment of the present invention.

  The blood purification apparatus 1 is an apparatus that removes waste products in blood by dialysis treatment in order to purify blood of patients with renal insufficiency or the like.

  Specifically, the blood purification apparatus 1 removes waste products in the blood with the dialysate and discharges the filtrate. In addition, in order to compensate for the decrease in the solvent in the blood, a replacement fluid is replenished to the blood. These dialysate, replacement fluid, and filtrate are stored in a measuring container, and in order to balance the flow rate of the dialysate and replacement fluid to be used with the flow rate of the discarded filtrate, the weight is measured with a weight meter. The weight of the container is measured.

  In addition, the dialysate and the replacement fluid come into contact with the patient's blood through the blood purifier (dialysis solution) and are injected into the blood returned to the patient (replacement fluid). The replacement fluid is heated to a temperature close to blood by a heating device.

  And these weight measuring devices and a heating apparatus are arrange | positioned in the position shown by A of the same figure. Below, these weight measuring devices and a heating apparatus are demonstrated in detail.

  FIG. 2 is a block configuration diagram showing blood purification apparatus 1 according to the embodiment of the present invention.

  As shown in the figure, the blood purification apparatus 1 includes a weight measuring device 10 and a heating device 20. In addition, the weight measuring device 10 and the heating apparatus 20 are arrange | positioned in the position of A shown in FIG.

  The blood purifier 60 is an instrument that purifies blood. Specifically, the blood purifier 60 allows a bundle of many hollow fibers to pass through the inside of the cylinder, conducts blood to the inside of the hollow fiber, and passes through the dialysate flowing in the cylinder and the hollow fiber membrane. Purifies blood by indirect contact. Due to the principle of diffusion, ultrafiltration and osmotic pressure, wastes in the blood such as urea, uric acid, creatine, and excess water are discharged into the dialysate, and electrolytes in the dialysate are taken into the blood.

  Here, the dialysate is a chemical that exchanges substances with blood in the blood purifier 60, and the replacement fluid is a chemical that replenishes water and electrolytes in the blood lost by passing through the blood purifier, In both cases, a chemical solution such as an isotonic solution adjusted so that the body fluid and the osmotic pressure and electrolyte are equal is used. For this reason, hereinafter, the dialysate and the replacement fluid are collectively referred to as a liquid supply.

  The weight measuring device 10 is a device that suspends a container that contains a fluid used for blood purification and measures the weight of the fluid. Here, the fluid used for blood purification is a liquid supply (dialysate and replacement fluid) and a filtrate. That is, the weight measuring device 10 suspends the liquid supply container 40 which is a measurement container in which the liquid supply is stored and the filtrate container 50 which is a measurement container in which the filtrate is stored, and measures the weight.

  The heating device 20 is a device that is suspended from the weight measuring instrument 10 and heats the liquid supply contained in the liquid supply container 40. Details of the heating device 20 will be described later.

  3A and 3B are diagrams for explaining the configuration of the heating device 20 in detail. Specifically, FIG. 3A is a view of the warming device 20 as seen from the left side of the blood purification device 1 shown in FIG. 1, and FIG. 3B is a view of the warming device 20 as seen from above.

  As shown in these drawings, the heating device 20 includes a heater 100 that is suspended from the weight measuring instrument 10 and that heats the liquid supply contained in the liquid supply container 40. The warmer 100 includes a first heating unit 110, a first holding member 120, and a slide member 130.

  The first holding member 120 is a resin flat plate member that holds the liquid supply container 40. That is, the liquid supply container 40 is attached and fixed to the first holding member 120. The 1st holding member 120 is provided with the heating surface part 120a which is a surface part to which the liquid supply container 40 is attached. In addition, the 1st holding member 120 should just be provided with the heating surface part 120a, and the material and shape of the 1st holding member 120 are not limited to the flat plate-shaped members made from resin.

  The heating surface portion 120a is inclined at a predetermined angle from the vertical direction, and contacts the liquid supply container 40 in a state where the liquid supply container 40 is disposed. The details of the heating surface portion 120a being inclined at a predetermined angle will be described later.

  Here, the liquid supply container 40 is a soft, flat bag-shaped container made of resin, and its shape is deformed depending on the amount of liquid supply accommodated and the direction in which the container is arranged. That is, the liquid supply container 40 is attached to the first holding member 120 so that the surface on the heating surface portion 120a side of the liquid supply container 40 and the heating surface portion 120a are in contact with each other.

  Accordingly, the first holding member 120 holds the liquid supply container 40 so that the liquid supply container 40 is inclined at a predetermined angle. The first holding member 120 corresponds to a “holding member” recited in the claims.

  The 1st heating part 110 is a metal flat plate-shaped member which heats the liquid supply accommodated in the liquid supply container 40 via the heating surface part 120a. Specifically, the first heating unit 110 generates heat by being heated and heats the liquid supply container 40 attached to the first holding member 120. In addition, the 1st heating part 110 is not limited to a metal flat member, The material and shape of the 1st heating part 110 may be anything as long as the liquid supply container 40 can be heated. Good.

  The slide member 130 is a member that advances and retracts the first holding member 120 in the horizontal direction with respect to the first heating unit 110. That is, the slide member 130 is a rail for pulling out and pushing in the first holding member 120 from the first heating unit 110 in order to detach the liquid supply container 40. Details of the slide member 130 will be described later.

  The heating device 20 includes a second heating unit 200 that further heats the liquid supply contained in the liquid supply container 40.

  The second heating unit 200 is a metal flat plate member disposed so as to sandwich the liquid supply container 40 with the first heating unit 110. Specifically, the second heating unit 200 is arranged in parallel with the heating surface unit 120a so as to cover the liquid supply container 40, and is connected and fixed to the first heating unit 110 by the connecting member 201. . And the 2nd heating part 200 emits heat by being heated, and heats the liquid supply container 40 attached to the 1st holding member 120. FIG. That is, the 2nd heating part 200 heats the surface of the liquid supply container 40 on the opposite side to the 1st heating part 110 heating.

  In addition, the 2nd heating part 200, the connection member 201, and the 1st heating part 110 may be integrally molded by bend | folding a metal flat plate, and may be formed by another member. Moreover, the 2nd heating part 200 is not limited to a metal flat member, The material and shape of the 2nd heating part 200 may be anything as long as the liquid supply container 40 can be heated. Good.

  Thus, since the 1st heating part 110 is attached to the weight measuring instrument 10, and the heating apparatus 20 is suspended from the weight measuring instrument 10, the weight measuring instrument 10 deducts the weight of the heating apparatus 20. Thus, the weight of the liquid supply container 40 is measured.

  In addition to the heating device 20, the blood purification device 1 also includes a second holding member 30 that holds the filtrate container 50.

  The second holding member 30 is a resin-made flat plate member suspended from the weight measuring instrument 10. That is, the filtrate container 50 is attached and fixed to the second holding member 30, and the weight measuring instrument 10 measures the weight of the filtrate container 50 through the second holding member 30. In addition, the 2nd holding member 30 should just hold the filtrate container 50, and the material and shape of the 2nd holding member 30 are not limited to resin flat members.

  In addition, since a filtrate is an effluent containing a waste product, it is not necessary to heat. For this reason, no heater is disposed around the filtrate container 50.

  Next, the inclination of the heating surface portion 120a will be described in detail.

  FIG. 4 is a diagram for explaining the inclination of the heating surface portion 120a.

  As shown in the figure, the warming surface portion 120a is disposed at an angle of a from the vertical direction (Y direction shown in the figure).

  Moreover, the 1st heating part 110 is provided with the 1st heating surface part 110a which is a surface at the side of the liquid supply container 40. As shown in FIG. And the 1st heating part 110 is arrange | positioned so that the 1st heating surface part 110a may become parallel to the heating surface part 120a.

  Furthermore, the 2nd heating part 200 is provided with the 2nd heating surface part 200a which is a surface at the side of the liquid supply container 40. As shown in FIG. And the 2nd heating part 200 is arrange | positioned so that the 2nd heating surface part 200a may become in parallel with the heating surface part 120a.

  And the inclination a degree of the heating surface part 120a becomes like this. Preferably, it is 10-30 degrees, More preferably, it is 15 degrees-20 degrees.

  When the a degree is less than 10 degrees, the liquid supply container 40 held by the first holding member is deformed by gravity, and the surface of the liquid supply container 40 on the heating surface part 120a side and the heating surface part 120a are sufficiently in contact with each other. I can't. For this reason, the surface on the heating surface portion 120a side of the liquid supply container 40 and the first heating surface portion 110a are not parallel, and the first heating portion 110 uniformly heats the liquid supply accommodated in the liquid supply container 40. Can not do it.

  Similarly, if the a degree is less than 10 degrees, the surface of the liquid supply container 40 on the second heating unit 200 side and the second heating surface unit 200a are not parallel, and the first heating unit 110 is evenly supplied. The liquid supply accommodated in the liquid container 40 cannot be heated.

  Moreover, since the whole heating apparatus 20 will incline rather than 30 degree | times if a degree is larger than 30 degree | times, in order to arrange | position the heating apparatus 20, it is necessary to ensure many spaces.

  And when a degree is 15 to 20 degree | times, the surface by the side of the heating surface part 120a of the liquid supply container 40 and the heating surface part 120a can fully contact | connect, and the space where the heating apparatus 20 is arrange | positioned is sufficient. It can be kept low.

  As described above, the inclination a degree of the heating surface portion 120a is preferably 10 to 30 degrees, and more preferably 15 to 20 degrees.

  Next, the slide member 130 will be described in detail.

  FIG. 5 is a diagram illustrating the configuration of the slide member 130. Specifically, FIG. 3 is a view of the state in which the first holding member 120 of the heating device 20 shown in FIG.

  As shown in the figure, the slide member 130 includes a first slide member 131 and a second slide member 132.

  The first slide member 131 is a metal rail with a concave cross section attached to the first heating unit 110.

  The second slide member 132 is a metal cross-section convex rail attached to the first holding member 120.

  That is, when the second slide member 132 is engaged with the first slide member 131 and moves back and forth in the horizontal direction (X direction shown in the figure), the first holding member 120 is horizontal with respect to the first heating unit 110. Advance and retreat in the direction.

  In addition, the first holding member 120 includes a grip portion 121 that is a handle when the first holding member 120 is advanced and retracted in the horizontal direction with respect to the first heating unit 110.

  FIG. 6 is a diagram illustrating that the slide member 130 moves the first holding member 120 forward and backward.

  The first holding member that holds the liquid supply container 40 by sliding the second slide member 132 with respect to the first slide member 131 by pulling the grip portion 121 in the X direction from the state of FIG. 120 is withdrawn.

  And it will be in the state as shown in (b) of the figure, and the liquid supply container 40 can be easily taken out from the heating apparatus 20 and removed from the first holding member 120.

  Further, when the liquid supply container 40 is stored in the heating device 20, the liquid supply container 40 is attached to the first holding member 120 by pulling the grip portion 121 in the X direction and pulling out the first holding member 120. . And the liquid supply container 40 attached to the 1st holding member 120 can be easily accommodated in the heating apparatus 20 by pushing in the holding part 121.

  As described above, according to the blood purification apparatus 1 of the present invention, the warming surface portion 120a is inclined with respect to the vertical direction, and the liquid supply container 40 comes into contact with the warming surface portion 120a, whereby the liquid supply container 40 is heated. It is placed on the warm surface portion 120a. For this reason, even if the amount of liquid supply in the liquid supply container 40 is small, it is possible to suppress the bias of the liquid supply in the liquid supply container 40 due to gravity, and evenly supply liquid while accurately measuring the liquid supply in the liquid supply container 40. The liquid supply in the container 40 can be heated.

  In addition, since the heating device 20 is integrated with the weight measuring instrument 10, since the measuring container and the heating container can be combined into one, the mounting operation is simplified and the space-saving arrangement is provided. Is possible.

  Moreover, since the inclination with respect to the vertical direction of the heating surface part 120a is as small as 10 to 30 degrees, it is not necessary to secure a large space for arranging the heating device 20.

  Moreover, since the liquid supply container 40 is arrange | positioned so that it may be pinched | interposed into the 1st heating part 110 and the 2nd heating part 200, the liquid supply accommodated in the liquid supply container 40 from the both sides of the liquid supply container 40 Can be heated.

  Further, the first holding member 120 holding the liquid supply container 40 can be advanced and retracted in the horizontal direction, and the liquid supply container 40 can be easily detached from the blood purification apparatus 1.

  Therefore, the dialysate and the replacement fluid stored in the liquid supply container 40 can be efficiently heated while saving the space and facilitating the detachment of the liquid supply container 40.

  As mentioned above, although the blood purification apparatus concerning this invention was demonstrated using the said embodiment, this invention is not limited to this.

  That is, the embodiment disclosed this time should be considered as illustrative in all points and not restrictive. The scope of the present invention is defined by the terms of the claims, rather than the description above, and is intended to include any modifications within the scope and meaning equivalent to the terms of the claims.

  For example, in the above embodiment, the first holding member 120 includes the heating surface portion 120a and holds the liquid supply container 40. However, as shown in FIG. 7, the 1st heating part 110 may be provided with the heating surface part 120a, and you may hold | maintain the liquid supply container 40. FIG. FIG. 7 is a diagram illustrating a configuration of the heating device 20 according to a modification of the present embodiment. According to this, although the removal | desorption of the liquid supply container 40 becomes easy, the 1st heating part 110 can heat the liquid supply container 40 efficiently.

  In the above embodiment, the dialysate and the replacement fluid are stored in one liquid supply container 40, and the heating device 20 heats the liquid supply stored in the liquid supply container 40. However, the dialysate and the replacement fluid may be stored in different measuring containers, and the heating device 20 may heat each measuring container. In this case, the blood purification apparatus 1 may include a plurality of heating devices 20 that heat each measuring container.

  The blood purification apparatus according to the present invention is useful, for example, as a blood purification apparatus capable of efficiently heating dialysate and replacement fluid to a patient with renal insufficiency when purifying the blood of the patient. is there.

DESCRIPTION OF SYMBOLS 1 Blood purification apparatus 10 Weight measuring device 20 Heating apparatus 30 2nd holding member 40 Liquid supply container 50 Filtration container 60 Blood purifier 100 Heater 110 1st heating part 110a 1st heating surface part 120 1st holding member 120a Heating surface portion 121 Grip portion 130 Slide member 131 First slide member 132 Second slide member 140 Suspension member 200 Second heating portion 200a Second heating surface portion 201 Connecting member

Claims (5)

A blood purification apparatus comprising a weight measuring device for measuring a weight of the fluid by hanging a container containing a fluid used for blood purification,
A heater that is suspended from the weight measuring instrument and that heats the fluid contained in the container,
The heater is
A blood purification apparatus comprising a heating surface portion that is inclined at a predetermined angle from a vertical direction and contacts the container in a state where the container is disposed. The blood purification apparatus according to claim 1, wherein the predetermined angle is 10 to 30 degrees. The warmer includes a first warming unit that warms the fluid stored in the container via the warming surface unit,
The blood purification device further includes:
The blood purification apparatus according to claim 1, further comprising a second heating unit that is disposed so as to sandwich the container with the first heating unit, and further heats the fluid stored in the container. The warmer further includes
A holding member that includes the heating surface portion and holds the container;
The blood purification apparatus according to any one of claims 1 to 3, further comprising a slide member that advances and retracts the holding member in a horizontal direction. A heater that suspends a container that contains a fluid used for blood purification and measures the weight of the fluid, and that heats the fluid.
A heating surface portion that comes into contact with the container in a state where the container is disposed at a predetermined angle from a vertical direction;
A warmer comprising: a first warming unit that warms the fluid stored in the container via the warming surface unit.

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