JP5369780B2 - Laminated body for sachet and packaging bag for sachet - Google Patents

Description

  The present invention relates to a laminate for packaging pharmaceuticals, foods, cosmetics and the like and a packaging bag for packaging, and more particularly, packaging useful for filling and packaging powdered or granular pharmaceutical products. The present invention relates to a laminated body for packaging and a packaging bag for packaging.

  Conventionally, various packaging bags have been proposed using synthetic resin films or sheets and used for filling and packaging various pharmaceuticals. For example, in the case of a pharmaceutical product in powder form or granular form, it is packaged in a wrapping form.

  In recent years, laminating films, etc., in which low-density polyethylene or the like is laminated on cellophane, can be easily torn by hand as a packaging laminate for filling and packaging pharmaceutical products. It is widely used because the contents of the bag can be visually confirmed (for example, Patent Document 1).

  In addition, from the viewpoint of safety to the human body, the administration period of internal medicines and external medicines was conventionally regulated by the Pharmaceutical Affairs Law as “Internal medicines and external medicines within 14 days at a time”. The “Responsibility for Medical Institutions and Insurance Medical Care” has been amended, and in principle, there will be no limit on the administration period, and a limit of 14 days, 30 days, and 90 days for each oral and external medicine prescribed by the Minister of Health, Labor and Welfare The content has been revised.

  For this reason, since a pharmaceutical product is stored in the packaging bag for a long time than before, there is an increasing demand for a packaging bag that does not change into a stored pharmaceutical product.

  However, when a packaging bag having a laminated film made of a conventional cellophane film is used, moisture that permeates the packaging laminate (hereinafter referred to as “moisture resistance”) is prevented. Insufficient and long-term storage has the problem that the medicine absorbs moisture and changes its quality.

  In addition, the conventional laminate for packaging using cellophane as a base material has poor dimensional accuracy due to changes in humidity and causes curling due to moisture absorption.

  In order to improve the moisture resistance and dimensional accuracy of conventional films, plastic film or vapor-deposited film such as silicon oxide can be used without using cellophane. There is a problem that it cannot be torn and opened.

  In addition, cellophane has the disadvantage of being inferior in cost performance as compared with plastic films such as polyethylene terephthalate and polypropylene.

  In addition, when cellophane is changed to a plastic film such as polyethylene terephthalate or polypropylene, in order to impart hand cutting properties, scratching is performed on a base material or a laminate (Patent Document 2). The number of processing steps increases, leading to an increase in cost, and there is still a problem because film fragments generated during processing may adhere to the packaging material and become foreign matter when scratch processing is performed.

Japanese Utility Model Publication No. 1-33765 JP 2005-305830 A

  The object of the present invention is excellent in gas barrier properties, moisture resistance, dimensional accuracy, mechanical suitability, and can be easily torn by hand, so that it is useful for filling and packaging powdered or granular pharmaceutical products. It is to provide a body and a packaging bag for packaging using the body.

  The present invention solves the problem by using an easily tearable aliphatic polyester stretched film.

The invention of claim 1 of the present invention is formed by laminating a transparent easily tearable aliphatic polyester-based stretched film with a sealant layer forming a heat seal layer through an electrostatic induction preventing layer, and the easily tearable A layered product for packaging characterized by laminating a gas barrier coating layer composed of a polyvinyl alcohol resin and an inorganic layered compound as an intermediate layer between the stretched aliphatic polyester film and the antistatic induction layer It is.

In the invention of claim 2 of the present invention, a vapor deposition layer is provided as an intermediate layer between the easily tearable aliphatic polyester stretched film and the electrostatic induction preventing layer, and a gas barrier coating layer is provided on the vapor deposition layer. The laminated body for packaging according to claim 1, wherein:
It is what.

  The invention of claim 3 of the present invention is a packaging bag for packaging characterized by being formed using the laminated body for packaging of claim 1 or 2.

The invention according to claim 4 of the present invention is the packaging bag for packaging according to claim 3 , characterized in that it is formed by connecting a plurality of storage parts for storing medicines in one direction. is there.

  As the easily tearable aliphatic polyester-based stretched film, a film that tears in all directions is suitable. For example, an easily tearable polyester in which a polyester film having a thickness of 6 μm and at least two polyester resin layers having different melting points are laminated. Etc. can be used.

  According to the first and second aspects of the present invention, the easily tearable aliphatic polyester-based stretched film does not have the necessary hand cutting ability unless laminated with aluminum foil or paper. As in the invention, in a configuration in which polyethylene is extruded and laminated on an easily tearable aliphatic polyester-based stretched film, necessary hand cutting properties can be obtained.

  Since the present invention is configured as described above, it has excellent gas barrier properties, moisture resistance, dimensional accuracy, and mechanical suitability, and can be easily torn by hand. It is possible to obtain a laminate for packaging useful for packaging and a packaging bag for packaging using the same. Furthermore, the processing process (scratch processing) that imparts hand-cutting properties is eliminated, which simplifies the processing, prevents foreign matter from entering in the processing step that provides hand-cutting properties (scratch processing), and has high production efficiency for packaging. It can be a bag.

It is explanatory drawing which showed the example of the laminated body for packaging of this invention in the cross section.

Embodiments of the present invention will be described below. FIG. 1 is an explanatory view showing a cross-section of one embodiment of the sachet of the present invention in cross section. FIG. 1 (a) shows an electrostatic charge on one side of a transparent easily tearable aliphatic polyester stretched film (1). The induction preventing layer (2) is laminated, and the molten resin is further extruded to form the sealant layer (3), thereby obtaining the packaging laminate of the present invention. Figure (b) shows the formation of a vapor-deposited layer (10) on one side of a transparent easily tearable aliphatic polyester stretched film (1), a further layer of antistatic induction (2), and extrusion of the molten resin. It is set as the sealant layer (3) and the laminated body for packaging of the present invention.

  In order to improve the adhesion of the deposited thin film layer to the surface of the easily tearable aliphatic polyester-based stretched film (1), pretreatment may be performed with corona treatment, low-temperature plasma treatment, ion bombardment treatment, Chemical treatment, solvent treatment, and the like may be performed.

  The thickness of the easily tearable aliphatic polyester stretched film (1) is not particularly limited, but considers suitability as a packaging material, processability when laminating other films or forming a vapor deposition layer, and the like. Then, the range of 5-30 micrometers is preferable.

  In consideration of mass productivity, it is desirable to use a long film so that the deposited thin film layer can be continuously formed. If it does in this way, the packaging bag for packaging formed by connecting a plurality of storage parts for storing medicines in one direction can be made into a long shape for mass production.

  The vapor deposition layer is made of silicon oxide, aluminum oxide, or magnesium oxide, and the film thickness is preferably in the range of 5 to 300 nm, and the value is appropriately selected. However, if the film thickness is 5 nm or less, a uniform thin film may not be formed on the entire surface of the transparent film substrate (1), and the function as a gas barrier material may not be sufficiently achieved. On the other hand, when the film thickness exceeds 300 nm, the deposited thin film cannot be kept flexible, and the deposited thin film may be cracked due to external factors such as bending and pulling after the deposition.

  Moreover, you may use the barrier property laminated film which laminated | stacked the gas barrier film layer which consists of a polyvinyl alcohol resin and an inorganic layered compound on a vapor deposition layer, The compounding ratio of the polyvinyl alcohol resin and an inorganic layered compound in that case is, When the polyvinyl alcohol resin / inorganic layered compound is in the range of 60/40 to 40/60 by weight% ratio, particularly high gas barrier properties can be obtained.

  The polyvinyl alcohol resin is generally obtained by saponifying polyvinyl acetate, and several tens percent of acetic acid groups remain. A completely saponified polyvinyl alcohol in which only several percent of acetic acid groups remain from a so-called partially saponified polyvinyl alcohol resin. Including resin, it is not particularly limited.

  Examples of the inorganic layered compound include a kaolinite group, a smectite group, and a mica group. Among these, smectite groups such as montmorillonite, hectorite, and saponite are preferable, and a resin is easily taken in between layers of the inorganic layered compound to easily form a composite. In particular, even higher gas barrier properties can be imparted by selecting montmorillonite from this group.

  The electrostatic induction preventing layer (2) is obtained by applying an electrostatic induction preventing agent containing polyethyleneimine as a main component by a gravure printing method or the like. This antistatic layering agent improves the adhesive strength with the transparent film substrate (1) and the sealant layer (3) made of polyethylene for sand lamination, and provides water resistance and solvent resistance. In addition, the antistatic effect can be imparted to the outer surface of the transparent film substrate (1) due to its electrostatic induction preventing performance.

Further, the electrostatic induction preventing agent will be described in detail. An anchor coating agent comprising a crosslinkable reactive polymer containing polyethyleneimine as a component and having electrostatic induction preventing properties. More specifically, for example, methyl methacrylate or A monomer such as acrylic acid is copolymerized in a mixed solvent of water and alcohol to form a solution for a transparent binder, and this solution is a main component of polyglycidyl ether of a divalent or tetravalent aliphatic alcohol as a crosslinking curing agent. Polyethyleneimine can be added and mixed, and the concentration can be adjusted with isopropyl alcohol or the like to obtain an electrostatic induction preventing agent. These electrostatic induction preventing anchor coating agents are applied to a transparent film substrate (1) by a gravure method, a roll coating method, a lip coating method or the like, dried at about 90 ° C. for several seconds, and a coating amount of 0.15 g to 0 An electrostatic induction preventing layer (2) having an electrostatic induction preventing property of 3 g / m ² (dry) can be obtained.

  The sealant layer (3) preferably has a thickness of about 30 to 50 μm such as linear low density polyethylene (LLDPE) or low density polyethylene (LDPE) as a resin excellent in heat sealability.

  Hereinafter, description will be made based on specific examples.

<Example 1>
As a transparent film substrate (1), a 12 μm thick easily tearable aliphatic polyester-based stretched film (Toyobo Co., Ltd., trade name: TF110) formed by laminating two types of polyester resin layers having different melting points Polymer antistatic agent containing polyethyleneimine as a main component: 10 parts by weight of BONDEIP-PA100 (manufactured by Altec) and 10 parts by weight of the curing agent with 20 parts of methanol and 15 parts of water The antistatic agent dissolved in the mixed solution is applied to one side of the transparent film substrate (1) by a gravure coating method, dried in an atmosphere of 90 ° C. with an air volume of 35 to 40 m ² , and applied. An electrostatic induction preventing layer (2) having a work amount of 0.2 g / m ² (dry) was obtained. Subsequently, a molten low density polyethylene is extruded on the surface of the antistatic induction layer (2) obtained above to form a sealant layer (3) having a thickness of 40 μm, thereby producing a laminated bag for packaging according to the present invention. did.

<Example 2>
In Example 1, except having laminated | stacked the gas barrier layer which consists of an inorganic stratiform compound and polyvinyl alcohol resin between the easily tearable aliphatic polyester-type stretched film and the electrostatic induction prevention layer, it carried out similarly to Example 1. A laminated bag for packaging according to the present invention was produced.

<Comparative example 1>
In Example 1, a comparison was made in the same manner except that a 12 μm thick biaxially stretched polyethylene terephthalate film (Futamura Chemical Co., Ltd., trade name: FE2201) was used as the transparent film substrate (1). Example 1 was made.

<Comparative example 2>
In Example 1, the transparent film substrate (1) was the same except that a transparent vapor-deposited polyethylene terephthalate film having a thickness of 12 μm without any tearability (Toppan Printing Co., Ltd., trade name: GL-AE) was used. Thus, Comparative Example 2 of the present invention was produced.

<Evaluation 1>
Evaluation was performed by the method for measuring the frictional voltage of the laminated bags for packaging in Examples 1 and 2 and Comparative Examples 1 and 2. The results are shown in Table 1.

<Measurement method 1>
JIS L1094 B method Based on frictional voltage measurement method. A cotton cloth (Kanakin No. 3) was used as the friction cloth. A sample is set in a test machine, and the change of the sample when rotated without rubbing for 60 seconds is recorded with a recorder. Both sides of the sample were measured.

<Evaluation 2>
In the three-sided bags obtained from Examples 1 and 2 and Comparative Examples 1 and 2, it was confirmed that the bag could be easily cut by hand from the edge.

From the results in Table 1, it was confirmed that sufficient antistatic properties were obtained in Examples 1 and 2 and Comparative Examples 1 and 2.

Moreover, from the results of Table 2, it was confirmed that Examples 1 and 2 were easily cut by hand as compared with Comparative Examples 1 and 2.

DESCRIPTION OF SYMBOLS 1 .... Transparent easily tearable aliphatic polyester-type stretched film 10 ... Deposition layer 2 .... Static induction prevention layer 3 .... Sealant layer

Claims (4)

A transparent easily stretchable aliphatic polyester stretched film is formed by laminating a sealant layer that forms a heat seal layer via an electrostatic induction preventing layer, and the easily tearable aliphatic polyester stretched film and electrostatic induction A laminate for packaging, wherein a gas barrier coating layer made of a polyvinyl alcohol resin and an inorganic layered compound is laminated as an intermediate layer between the prevention layer and the prevention layer . 2. A vapor deposition layer is provided as an intermediate layer between the easily tearable aliphatic polyester-based stretched film and the electrostatic induction preventing layer, and a gas barrier coating layer is provided on the vapor deposition layer. Laminate for packaging.   A packaging bag for packaging, which is formed using the packaging laminate according to claim 1 or 2. 4. The packaging bag according to claim 3 , wherein a plurality of storage portions for storing a medicine are continuously provided in one direction.

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