JP5509452B2 - EEG display apparatus, EEG display method, and program - Google Patents

Description

  The present invention relates to an electroencephalogram display device.

  For example, Patent Document 1 discloses a brain function site estimation system that estimates a brain function from a head surface position of a subject using a three-dimensional position measurement device.

JP 2009-160281 A

  The present invention provides an electroencephalogram display device capable of calculating an electroencephalogram in a standard brain expressed in three dimensions with simple equipment.

An electroencephalogram display device according to the present invention includes an electroencephalogram measurement means for measuring electroencephalograms at a plurality of parts of the head, a two-dimensional electroencephalogram calculation means for calculating a two-dimensional electroencephalogram based on the electroencephalogram measured by the electroencephalogram measurement means, and And a three-dimensional electroencephalogram calculation means for calculating an electroencephalogram in a standard brain expressed in three dimensions based on the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation means.
Preferably, the three-dimensional electroencephalogram calculation means is a modification that expands and contracts the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation means and transforms it into the same form as a standard brain expressed in two dimensions. Processing, a cutting process for concentrically cutting the two-dimensional electroencephalogram deformed by the deformation process, and each part of the two-dimensional electroencephalogram cut by the cutting process is represented in a three-dimensional standard brain A standard expressed in three dimensions by executing a pasting process to be pasted at a corresponding position on the surface of the image and an interpolation process for interpolating a gap between each part of the two-dimensional electroencephalogram pasted by the pasting process. An electroencephalogram in the brain is calculated.

  Further, the program according to the present invention includes an electroencephalogram measurement function that measures electroencephalograms at a plurality of parts of the head, and a two-dimensional electroencephalogram calculation function that calculates a two-dimensional electroencephalogram based on the electroencephalograms measured by the electroencephalogram measurement function. The computer realizes a three-dimensional electroencephalogram calculation function for calculating an electroencephalogram in the standard brain expressed in three dimensions based on the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation function.

  Further, the electroencephalogram display method according to the present invention includes an electroencephalogram measurement step for measuring electroencephalograms at a plurality of parts of the head, and a two-dimensional electroencephalogram calculation for calculating a two-dimensional electroencephalogram based on the electroencephalogram measured by the electroencephalogram measurement step. And a three-dimensional electroencephalogram calculation step for calculating an electroencephalogram in a standard brain expressed in three dimensions based on the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation step.

  According to the present invention, an electroencephalogram in a standard brain expressed in three dimensions can be calculated with simple equipment.

It is a figure showing the state which is measuring the electroencephalogram using the electroencephalogram display apparatus. 2 is a diagram illustrating a functional configuration of an electroencephalogram display program 100. FIG. It is a schematic diagram which illustrates steps 1-4 in electroencephalogram standardization processing S10. It is a figure which illustrates the three-dimensional electroencephalogram (The electroencephalogram in the standard brain represented by three dimensions) calculated based on the two-dimensional electroencephalogram.

FIG. 1 is a diagram showing a state in which an electroencephalogram is measured using an electroencephalogram display device 10.
As illustrated in FIG. 1, the electroencephalogram display device 10 is connected to an electroencephalogram cap 20 placed on a subject via a signal cable 40.

  The electroencephalogram display apparatus 10 is a computer including a CPU and a storage medium, and an electroencephalogram display program 100 (described later with reference to FIG. 2) is installed. A plurality of electrodes 30 are arranged on the electroencephalogram cap 20. The position where the electrode 30 is disposed on the electroencephalogram cap 20 is not particularly limited. For example, the electrode 30 may be disposed on the electroencephalogram cap 20 based on an international 10-20 electrode placement method or the like. By covering the brain wave cap 20 on the subject, the electrode 30 is placed at a predetermined position on the subject's head. The electroencephalogram display apparatus 10 measures the electroencephalogram at a predetermined position on the subject's head using each electrode 30 disposed on the electroencephalogram cap 20. Then, the electroencephalogram display apparatus 10 calculates an electroencephalogram in a standard brain expressed in three dimensions based on the measured electroencephalogram by executing an electroencephalogram standardization process S10 (described later with reference to FIG. 3). An electroencephalogram is represented by the magnitude of a potential, current, magnetic field, or the like in each part of the brain. The standard brain is modeled so that the data of a plurality of subjects can be normalized and the brain images of each subject can be identified by coordinates. As the standard brain, for example, there is a Taillac brain or a Montreal brain.

  As described above, the electroencephalogram display apparatus 10 can calculate an electroencephalogram in the standard brain expressed in three dimensions with simple equipment.

FIG. 2 is a diagram illustrating a functional configuration of the electroencephalogram display program 100.
As illustrated in FIG. 2, the electroencephalogram display program 100 includes an electroencephalogram measurement unit 102, a two-dimensional electroencephalogram calculation unit 104, a three-dimensional electroencephalogram calculation unit 106, and a display unit 108. The electroencephalogram display program 100 is executed using the hardware resources (CPU, storage medium, etc.) of the electroencephalogram display apparatus 10. The electroencephalogram display program 100 may be partially or entirely realized by hardware such as an ASIC.

The electroencephalogram measurement unit 102 measures electroencephalograms at a plurality of parts of the head.
In the present embodiment, the electroencephalogram measurement unit 102 receives and measures the electroencephalogram detected by the electrode 30 disposed on the electroencephalogram cap 20 via the signal cable 40.

The two-dimensional electroencephalogram calculation unit 104 calculates a two-dimensional electroencephalogram based on the electroencephalogram measured by the electroencephalogram measurement unit 102.
In the present embodiment, the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation unit 104 represents the magnitude of the electroencephalogram measured by the electroencephalogram measurement unit 102 as a contour map.

The three-dimensional electroencephalogram calculation unit 106 calculates an electroencephalogram in the standard brain expressed in three dimensions based on the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation unit 104.
In this embodiment, the electroencephalogram calculated by the three-dimensional electroencephalogram calculation unit 106 is a standard brain expressed in three dimensions by processing the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation unit 104 by image processing. Is pasted on.

  The display unit 108 outputs the electroencephalogram in the standard brain calculated by the three-dimensional electroencephalogram calculation unit 106 to a display device such as a display.

FIG. 3 is a schematic view illustrating steps 1 to 4 in the electroencephalogram standardization process S10.
As illustrated in FIG. 3, in step 1, the two-dimensional electroencephalogram calculation unit 104 calculates a two-dimensional electroencephalogram representing the magnitude of the electroencephalogram measured by the electroencephalogram measurement unit 102 with a contour map.

  In step 2, the three-dimensional electroencephalogram calculation unit 106 expands and contracts the two-dimensional electroencephalogram calculated in step 1 and transforms it into the same form as the standard brain expressed in two dimensions. More specifically, the three-dimensional electroencephalogram calculation unit 106 matches the two-dimensional electroencephalogram calculated in step 1 with the standard brain expressed in two dimensions so that the center portions O of the two-dimensional electroencephalograms coincide with each other. Overlapping. Then, the three-dimensional electroencephalogram calculation unit 106 expands and contracts the two-dimensional electroencephalogram calculated in step 1 on the radiation from the central portion O, and deforms it into the same form as the standard brain represented in two dimensions. .

  In step 3, the three-dimensional electroencephalogram calculation unit 106 cuts the two-dimensional electroencephalogram deformed in step 2 concentrically at a predetermined interval. Then, the three-dimensional electroencephalogram calculation unit 106 pastes each part of the cut two-dimensional electroencephalogram on the corresponding position on the surface of the standard brain represented in three dimensions.

  In step 4, the three-dimensional electroencephalogram calculation unit 106 interpolates a gap between each part of the two-dimensional electroencephalogram pasted in step 3. The method for interpolating the gaps between the portions of the two-dimensional electroencephalogram pasted in step 3 is not particularly limited. For example, the three-dimensional electroencephalogram calculation unit 106 may interpolate the gaps between the portions of the two-dimensional electroencephalogram pasted in step 3 using a linear interpolation method or a spline interpolation method.

FIG. 4 is a diagram illustrating a three-dimensional electroencephalogram (an electroencephalogram in a standard brain expressed in three dimensions) calculated based on the two-dimensional electroencephalogram.
As illustrated in FIG. 4, the electroencephalogram display program 100 executes the above-described electroencephalogram standardization process S <b> 10, and thereby, based on the two-dimensional electroencephalogram 200 calculated by the two-dimensional electroencephalogram calculator 104, 3D electroencephalogram 210 viewed from the rear side, the left side, the right side, and the upper side.

Through the processing described above, the electroencephalogram display device 10 can display the electroencephalogram measured as one-dimensional data in association with the standard brain represented in three dimensions. Thereby, the user can create an average image and a standard deviation map of an electroencephalogram based on the standard brain, and objectively compare and analyze the measured electroencephalogram and the electroencephalogram of a normal person. Furthermore, the electroencephalogram display device 10 associates the electroencephalogram with a standard brain used in cerebral blood flow SPECT or FDG-PET, so that the user examines the relationship between the cerebral blood flow or cerebral metabolism and the electroencephalogram, A specific disease or the like in Alzheimer's disease can be diagnosed.
Note that the electroencephalogram display device 10 may display the electroencephalogram image converted into the standard brain and another examination image related to the brain in an overlapping manner.

DESCRIPTION OF SYMBOLS 10 EEG display apparatus 20 EEG cap 30 Electrode 100 EEG display program 102 EEG measurement part 104 Two-dimensional EEG figure calculation part 106 Three-dimensional EEG figure calculation part 108 Display part

Claims (3)

An electroencephalogram measuring means for measuring electroencephalograms at a plurality of parts of the head;
A two-dimensional electroencephalogram calculation means for calculating a two-dimensional electroencephalogram based on the electroencephalogram measured by the electroencephalogram measurement means;
Based on said two-dimensional electroencephalogram calculated by two-dimensional electroencephalogram calculating means, possess a three-dimensional electroencephalogram calculating means for calculating the electroencephalogram in standard brain represented in three dimensions,
The three-dimensional electroencephalogram calculation means includes:
Deformation processing for expanding and contracting the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation means, and transforming it into the same form as the standard brain represented in two dimensions;
A cutting process for concentrically cutting the two-dimensional electroencephalogram deformed by the deformation process;
A pasting process for pasting each part of the two-dimensional electroencephalogram cut by the cutting process to a corresponding position on the surface of the standard brain represented in three dimensions;
An interpolation process for interpolating a gap between each part of the two-dimensional electroencephalogram pasted by the pasting process;
An electroencephalogram display device that calculates an electroencephalogram in a standard brain expressed in three dimensions by executing An electroencephalogram measurement function for measuring electroencephalograms at multiple parts of the head;
A two-dimensional electroencephalogram calculation function for calculating a two-dimensional electroencephalogram based on the electroencephalogram measured by the electroencephalogram measurement function;
Based on the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation function, the computer realizes a three-dimensional electroencephalogram calculation function for calculating an electroencephalogram in the standard brain represented in three dimensions ,
The three-dimensional electroencephalogram calculation function is:
A deformation process for expanding and contracting the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation function, and transforming it into the same form as the standard brain represented in two dimensions;
A cutting process for concentrically cutting the two-dimensional electroencephalogram deformed by the deformation process;
A pasting process for pasting each part of the two-dimensional electroencephalogram cut by the cutting process to a corresponding position on the surface of the standard brain represented in three dimensions;
An interpolation process for interpolating a gap between each part of the two-dimensional electroencephalogram pasted by the pasting process;
The program which calculates the electroencephalogram in the standard brain expressed in three dimensions by executing . An electroencephalogram measurement step for measuring electroencephalograms at a plurality of parts of the head; and
A two-dimensional electroencephalogram calculation step for calculating a two-dimensional electroencephalogram based on the electroencephalogram measured by the electroencephalogram measurement step;
Based on the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation step, it possesses a three-dimensional electroencephalogram calculating a electroencephalogram in standard brain represented in three dimensions,
The three-dimensional electroencephalogram calculation step includes:
Deformation processing for expanding and contracting the two-dimensional electroencephalogram calculated by the two-dimensional electroencephalogram calculation step, and transforming it into the same form as the standard brain represented in two dimensions;
A cutting process for concentrically cutting the two-dimensional electroencephalogram deformed by the deformation process;
A pasting process for pasting each part of the two-dimensional electroencephalogram cut by the cutting process to a corresponding position on the surface of the standard brain represented in three dimensions;
An interpolation process for interpolating a gap between each part of the two-dimensional electroencephalogram pasted by the pasting process;
EEG display method including

Images