JP5929022B2 - Extracorporeal circulation device and priming method thereof - Google Patents

Description

  The present invention relates to an extracorporeal circulation device and a priming method thereof, and more particularly, to an extracorporeal circulation device that is used for extracorporeal circulation of blood after the priming operation and a priming method in the extracorporeal circulation device.

  Extracorporeal circulation devices are used for patients who require severe heart failure such as myocardial infarction, low-output syndrome after open heart surgery, assisted circulation by macrovascular surgery, and emergency cardiopulmonary resuscitation for cardiopulmonary arrest. The extracorporeal circulation device includes an extracorporeal circulation circuit for blood removal and blood return. By using an extracorporeal circulation device, for patients with ventricular fibrillation or decreased cardiac output, it is possible to secure a predetermined blood flow as an auxiliary circulation of the heart, and for patients whose blood flow has stopped As a result, it is possible to return to the state where the blood is circulating.

  As disclosed in JP 2006-130078 (Patent Document 1) and JP 2007-236564 A (Patent Document 2), before the extracorporeal circulation device is used for extracorporeal circulation of blood, extracorporeal circulation. A priming operation is performed on the circuit.

  When using an extracorporeal circulation device, the patient's blood vessel is cannulated (referred to as cannulation). An extracorporeal circuit is connected to a cannula inserted into the patient's blood vessel. The priming operation is performed before the extracorporeal circuit is connected to the cannula.

  In the priming operation, a priming solution such as physiological saline is introduced into the extracorporeal circuit. The air in the extracorporeal circuit is discharged to the outside by the priming liquid. By performing the priming operation, the air remaining in the extracorporeal circuit is prevented from entering the patient's body.

  After completion of the priming operation, the extracorporeal circuit blood removal port is connected to a cannula inserted into the patient's femoral vein. The blood return port of the extracorporeal circuit is connected to a cannula inserted into the patient's femoral artery. The extracorporeal circulation device circulates blood through these two cannulas. As a result, the patient can be returned to a state in which blood is circulating.

JP 2006-130078 A JP 2007-236564 A

  In the medical field where the extracorporeal circulation device is used, it is not limited to the priming operation of the extracorporeal circulation device, the cannula is inserted into the patient's blood vessel by the doctor, various medical instruments are prepared by the technician, the nurse Various chemicals are prepared by. It is desired that the priming operation in the extracorporeal circulation apparatus is efficiently performed without requiring human resources as much as possible.

  An object of the present invention is to provide an extracorporeal circulation device and a priming method thereof that can efficiently perform a priming operation without requiring human resources as much as possible.

An extracorporeal circulation apparatus according to the present invention is an extracorporeal circulation apparatus used for extracorporeal circulation of blood after a priming operation is performed, and includes a pump unit driven by a drive unit, and a position above the pump unit in the direction of gravity. A blood processing unit disposed in the body, and an extracorporeal circuit that is formed in an annular shape and communicates with the pump unit and the blood processing unit, and is connected to the extracorporeal circuit and introduces a priming solution into the extracorporeal circuit A priming fluid introduction section, an air discharge section connected to the extracorporeal circulation circuit and disposed above the blood treatment section in the direction of gravity, and the priming fluid introduction section introduced into the extracorporeal circulation circuit from the priming fluid introduction section. The priming liquid is in a region above the pump unit in the gravity direction in the extracorporeal circuit, and below the air discharge unit in the gravity direction. And when the priming operation is carried out, the priming fluid is introduced into the extracorporeal circuit from the priming fluid introduction unit, whereby the extracorporeal circulation is detected. The air in the circuit is discharged to the outside through the air discharge unit, and the drive unit drives the pump unit after a predetermined time has elapsed since the detection unit has detected that the priming liquid has reached the region. is, by the pump unit, the priming liquid circulates in the extracorporeal circuit, air remaining in the above extracorporeal circulation circuit, by the priming fluid circulating in the extracorporeal circuit of the blood treatment unit A part of the air that has reached the inside of the blood processing unit is not allowed to pass through the extracorporeal circuit, so that the blood It is discharged to the outside of the processing section.

  Preferably, the pump unit is a centrifugal pump capable of feeding a liquid by centrifugal force. Preferably, the blood processing unit is an artificial lung that removes carbon dioxide from the blood and adds oxygen to the blood.

A priming method for an extracorporeal circulation device according to the present invention is a priming method for an extracorporeal circulation device used for extracorporeal circulation of blood. The extracorporeal circulation device includes a pump unit driven by a driving device, and a pump unit. Is connected to the extracorporeal circuit and the extracorporeal circuit that is formed in an annular shape and communicates with the pump unit and the blood processor, and is connected to the extracorporeal circuit. A priming fluid introduction section that introduces a priming fluid into the body, an air discharge section that is connected to the extracorporeal circuit and is disposed above the blood treatment section in the direction of gravity, and from the priming fluid introduction section into the extracorporeal circuit. The priming liquid introduced into the body is above the pump part in the extracorporeal circulation circuit in the direction of gravity and from the air discharge part. A detection unit that detects that the region has reached a region below the direction of gravity, and the air in the extracorporeal circuit is introduced by introducing the priming solution from the priming solution introduction unit into the extracorporeal circuit. A step of discharging to the outside through the air discharge unit, and a step of driving the pump unit by the driving device after a predetermined time has elapsed after the detection unit detects that the priming liquid has reached the region. When provided with, by the pump unit, the priming liquid circulates in the extracorporeal circuit, air remaining in the extracorporeal circuit, said blood by said priming fluid circulating in the extracorporeal circuit A part of the air that has reached the treatment unit and has reached the blood treatment unit does not pass through the extracorporeal circulation circuit, and thus rises from the blood treatment unit. It is discharged to the outside of the blood treatment unit.

  ADVANTAGE OF THE INVENTION According to this invention, the extracorporeal circulation apparatus and its priming method which can perform a priming operation | movement efficiently without requiring human resources as much as possible can be obtained.

It is a figure which shows the extracorporeal circulation apparatus in embodiment. It is a figure which shows the 1st process of the priming method of the extracorporeal circulation apparatus in embodiment. It is a figure which shows the 2nd process of the priming method of the extracorporeal circulation apparatus in embodiment. It is a figure which shows the 3rd process of the priming method of the extracorporeal circulation apparatus in embodiment. It is a figure which shows the 4th process of the priming method of the extracorporeal circulation apparatus in embodiment. It is a figure which shows the 5th process of the priming method of the extracorporeal circulation apparatus in embodiment. It is a figure which shows the 6th process of the priming method of the extracorporeal circulation apparatus in embodiment. It is a figure which shows the 7th process of the priming method of the extracorporeal circulation apparatus in embodiment. It is a figure which shows a mode that the blood removal port and the blood return port were formed in the extracorporeal circuit of the extracorporeal circulation apparatus in embodiment. It is a figure which shows a mode that the extracorporeal circuit of the extracorporeal circulation apparatus in embodiment was connected to the cannula. It is a figure which shows the extracorporeal circulation apparatus in the 1st modification of embodiment. It is a figure which shows the extracorporeal circulation apparatus in the 2nd modification of embodiment. It is a figure which shows the extracorporeal circulation apparatus in the 3rd modification of embodiment. It is a figure which shows the extracorporeal circulation apparatus in the 4th modification of embodiment.

  Embodiments based on the present invention will be described below with reference to the drawings. In the description of the embodiments, when referring to the number, amount, and the like, the scope of the present invention is not necessarily limited to the number, amount, or the like unless otherwise specified. In the description of the embodiments, the same parts and corresponding parts are denoted by the same reference numerals, and redundant description may not be repeated.

(Extracorporeal circulation device 100)
FIG. 1 is a diagram illustrating an extracorporeal circulation device 100 according to an embodiment. The extracorporeal circulation device 100 includes a centrifugal pump 10 (pump unit), an artificial lung 20 (blood processing unit), an extracorporeal circulation circuit 30, a priming fluid introduction unit 40, an air discharge unit 50, and a detection unit 60. Although details will be described later, a priming operation is performed on the extracorporeal circuit 30 of the extracorporeal circulation apparatus 100. After this priming operation is performed, the extracorporeal circulation device 100 is used for extracorporeal circulation or auxiliary circulation of blood.

  The centrifugal pump 10 sends a liquid such as a priming liquid or blood by centrifugal force. The centrifugal pump 10 is driven by a driving device 12 connected to the controller 14. The controller 14 is provided with a power switch 16. In the extracorporeal circulation device 100, instead of the centrifugal pump 10, a squeeze pump (a pump that operates to squeeze the elastic tube from the outside with a roller and squeeze the liquid), a roller blood pump, or the like is used as a pump unit. May be used as

  The artificial lung 20 is disposed above the centrifugal pump 10 in the gravity direction. The artificial lung 20 is composed of a plurality of hollow fiber membranes (not shown) bundled together. The artificial lung 20 removes carbon dioxide from the blood and adds oxygen to the blood. In the extracorporeal circulation device 100, instead of the artificial lung 20, a specific substance is removed from the blood, a specific substance is added to the blood, or the blood temperature is adjusted to a predetermined value. A thing etc. may be used as a blood processing part.

  The extracorporeal circuit 30 is formed in an annular shape from a tubular member. The extracorporeal circuit 30 includes a first path 32 and a second path 34. The second path 34 of the extracorporeal circuit 30 communicates with the inside of the centrifugal pump 10 and the inside of the oxygenator 20. The centrifugal pump 10 and the artificial lung 20 are configured as a part of the extracorporeal circuit 30.

  The priming liquid introduction unit 40 includes a priming liquid 42, a storage bag 44, and a priming line 46. The priming liquid introduction unit 40 introduces the priming liquid 42 into the extracorporeal circuit 30. The priming liquid 42 is, for example, physiological saline. The storage bag 44 stores the priming liquid 42. The priming line 46 is formed from a tubular member. In the present embodiment, the storage bag 44 is disposed above the extracorporeal circuit 30 in the direction of gravity.

  One end of the priming line 46 is connected to the storage bag 44. The other end of the priming line 46 is connected to the extracorporeal circuit 30. The extracorporeal circuit 30 branches from a portion connected to the priming line 46 into a first path 32 and a second path 34. The 1st path | route 32 and the 2nd path | route 34 merge in the vicinity of the air discharge part 50 mentioned later.

  As the priming fluid introduction section 40, in addition to the priming fluid 42 introduced into the extracorporeal circulation circuit 30 by a drop, the priming fluid 42 enters the extracorporeal circulation circuit 30 by the pressure applied to the priming fluid 42 from the outside. May be introduced. When the priming liquid 42 is introduced into the extracorporeal circuit 30 by external pressure, the storage bag 44 may be provided above the extracorporeal circuit 30 in the gravitational direction, and the gravitational direction more than the extracorporeal circuit 30. Or may be provided at the same height as the extracorporeal circuit 30.

  The air discharge unit 50 is also connected to the extracorporeal circuit 30. The air discharge unit 50 is disposed above the artificial lung 20 in the gravity direction. Preferably, the air discharge part 50 is arrange | positioned at the uppermost part of the gravity direction of the extracorporeal circuit 30. FIG. Specifically, the air discharge unit 50 includes a hydrophobic filter 52, a housing case 54, an opening / closing cock 56, and a discharge line 58. A discharge line 58 is connected to the extracorporeal circuit 30. An open / close cock 56 is provided on the discharge line 58. A hydrophobic filter 52 is provided in the housing case 54.

  The hydrophobic filter 52 is composed of a member having a porous structure, for example. A member having a porous structure tends to repel water droplets because of its low surface tension. The hydrophobic filter 52 can restrict the passage of the priming liquid 42 while ensuring air permeability. As a material of the member used for the hydrophobic filter 52, for example, it is obtained by polymerizing or copolymerizing monomers such as cellulose, polytetrafluoroethylene resin, ethylene, propylene, 4-methylpentene-1, 1-butene alone. And polyolefin resin.

  The detection unit 60 includes a flow rate sensor connected to the controller 14. The detection unit 60 detects that the priming liquid 42 introduced into the extracorporeal circuit 30 from the priming liquid introduction unit 40 has reached a predetermined region 36 in the extracorporeal circuit 30.

  The region 36 is a region above the centrifugal pump 10 in the gravity direction in the extracorporeal circuit 30 and below the air discharge unit 50 in the gravity direction. The region 36 in the present embodiment is a region above the artificial lung 20 in the extracorporeal circuit 30 in the gravity direction and below the air discharge unit 50 in the gravity direction. As the detector 60, a sensor other than a flow sensor is used as long as it detects the priming liquid 42 flowing through the region 36 in the extracorporeal circuit 30 based on optical, electrical, or electromagnetic means. May be.

(Priming operation of extracorporeal circulation device 100)
With reference to FIGS. 2-8, the priming operation | movement (priming method of the extracorporeal circulation apparatus 100) implemented with respect to the extracorporeal circulation circuit 30 of the extracorporeal circulation apparatus 100 is demonstrated.

  As shown in FIG. 2, when using the extracorporeal circulation apparatus 100, first, various devices constituting the extracorporeal circulation apparatus 100 are prepared (see also FIG. 10). At the time when various devices are prepared, the detection unit 60 is separated from the extracorporeal circuit 30. The driving device 12 is separated from the centrifugal pump 10. The priming line 46 is also not connected to the storage bag 44.

  After various devices are prepared, the drive device 12 is attached to the centrifugal pump 10 (see arrow AR1). The detector 60 is attached to the region 36 of the extracorporeal circuit 30 (see arrow AR2). The priming line 46 is connected (punctured) to the storage bag 44 (see arrow AR3).

  Next, the power switch 16 of the controller 14 is turned on. The power switch 16 may be turned on before the priming line 46 is connected to the storage bag 44. The power switch 16 may be turned on before the detection unit 60 is attached to the region 36 of the extracorporeal circuit 30. The power switch 16 may be turned on before the drive device 12 is attached to the centrifugal pump 10. When the power switch 16 is turned on, the driving device 12 is not driving the centrifugal pump 10.

  Although details will be described below, the actions of a worker (such as a doctor, a technician, or a nurse) necessary for the priming operation of the extracorporeal circulation device 100 are only the above operations. In the extracorporeal circulation device 100, the subsequent priming operation is automatically performed until the priming operation is completed.

  Accordingly, the doctor can leave the extracorporeal circuit 30 or the like and cannulate the patient's blood vessel (cannulation) or make other preparations. The engineer can also prepare various medical instruments and the like away from the extracorporeal circuit 30 and the like. The nurse can also prepare various chemicals and the like away from the extracorporeal circuit 30 and the like.

  Referring to FIG. 3, priming line 46 communicates with the inside of storage bag 44 by connecting priming line 46 to storage bag 44. The priming liquid 42 flows downward in the direction of gravity in the priming line 46 due to its own weight (see arrow AR4). The air in the extracorporeal circuit 30 is discharged to the outside through the discharge line 58, the open / close cock 56, and the hydrophobic filter 52 (see arrow DR1).

  Referring to FIG. 4, priming liquid 42 passes through priming line 46 and is introduced into extracorporeal circuit 30 (second path 34) (see arrow AR5). The air in the extracorporeal circuit 30 is continuously discharged to the outside through the discharge line 58, the open / close cock 56, and the hydrophobic filter 52 (see arrow DR1).

  Referring to FIG. 5, the priming liquid 42 flows upward in the direction of gravity in the first path 32 due to a drop between the priming liquid introducing unit 40 and the extracorporeal circuit 30 (see arrow AR6). The priming liquid 42 also flows upward in the direction of gravity in the second path 34 (see arrow AR7).

  The priming liquid 42 flowing in the first path 32 and the priming liquid 42 flowing in the second path 34 further flow upward in the direction of gravity. The priming liquid 42 flowing in the second path 34 passes through the inside of the centrifugal pump 10. Thereafter, the priming solution 42 flowing in the second path 34 passes through the inside of the artificial lung 20.

  Referring to FIG. 6, the priming liquid 42 flowing in the first path 32 further flows upward in the direction of gravity (see arrow AR7). The priming liquid 42 flowing in the second path 34 further flows upward in the direction of gravity (see arrow AR8).

  As shown in FIG. 6, it is assumed that the priming liquid 42 flowing in the second path 34 reaches the region 36. The detection unit 60 detects that the priming liquid 42 has reached the region 36. This information is input to the controller 14 as a signal. The controller 14 has a built-in timer (not shown), and after a predetermined time (for example, 10 to 20 seconds) has elapsed since the detection unit 60 detects that the priming liquid 42 has reached the region 36. Then, the driving device 12 is driven.

  Referring to FIG. 7, the extracorporeal circulation circuit 30 is between the detection unit 60 detecting that the priming liquid 42 has reached the region 36 and the elapse of a predetermined time (for example, 10 seconds to 20 seconds). The inside and the inside of the discharge line 58 are filled with the priming liquid 42. Most of the air present in the priming line 46, the extracorporeal circuit 30, the centrifugal pump 10, the artificial lung 20, and the discharge line 58 is discharged to the outside.

  The air that has not been discharged to the outside is very small in the centrifugal pump 10, the artificial lung 20, and the extracorporeal circuit 30 (the joint between the extracorporeal circuit 30 and the priming line 46 or the portion where the extracorporeal circuit 30 is bent). It remains as a simple bubble. In the extracorporeal circulation device 100, the driving device 12 drives the centrifugal pump 10 to discharge minute bubbles.

  Referring to FIG. 8, specifically, controller 14 drives drive device 12 after the elapse of the predetermined time (for example, 10 seconds to 20 seconds). The priming solution 42 circulates in the extracorporeal circuit 30, the inside of the centrifugal pump 10, and the inside of the oxygenator 20 by the centrifugal pump 10 (see arrow AR9). Bubbles (air) remaining in the extracorporeal circuit 30 or the like are discharged from the extracorporeal circuit 30 to the outside by the circulation of the priming liquid 42.

  In the present embodiment, bubbles (air) remaining in the extracorporeal circuit 30 or the like are discharged to the outside through the artificial lung 20 (see arrow DR2). At this time, the open / close cock 56 may be closed, or the open / close cock 56 may be provided at a position in the extracorporeal circuit 30 where there is no negative pressure (for example, near the downstream of the centrifugal pump 10). Alternatively, a one-way valve (check valve) may be provided instead of the opening / closing cock 56. Air bubbles (air) remaining in the extracorporeal circuit 30 or the like are passed from the inside of the hollow fiber membrane to the outside (artificial) by passing the priming liquid 42 through the plurality of hollow fiber membranes constituting the artificial lung 20. It is discharged toward the outside of the lung 20).

  In the extracorporeal circuit 30 or the like, the priming solution 42 is circulated for about 5 minutes, for example. Bubbles remaining in the extracorporeal circuit 30, the centrifugal pump 10, and the artificial lung 20 can be completely discharged from the extracorporeal circuit 30 to the outside. Thus, the priming operation of extracorporeal circulation device 100 is completed.

  Referring to FIG. 9, after the priming operation is completed, extracorporeal circuit 30 is disconnected at a predetermined position. A blood removal port 33 and a blood return port 35 are formed in the extracorporeal circuit 30. The position at which the extracorporeal circuit 30 is cut is not limited to the position shown in FIG. The extracorporeal circuit 30 may be cut at other positions that do not separate the air discharge part 50 from the extracorporeal circuit 30, for example.

  Referring to FIG. 10, while the priming operation is performed, the cannula 72 is percutaneously inserted into the patient's general artery 82 by cannulation. The cannula 74 is inserted percutaneously into the patient's general vein 84. The tip of cannula 74 is placed in right atrium 86. The blood removal port 33 of the extracorporeal circuit 30 is connected to a cannula 74. The blood return port 35 of the extracorporeal circuit 30 is connected to a cannula 72.

  When the extracorporeal circulation device 100 is used, in addition to the above, a gantry 68, an oxygen tank 62, a battery 64, a heat exchanger 66, and the like are prepared. As described above, the extracorporeal circulation device 100 that has been prepared, primed, and installed can be used for extracorporeal circulation of blood.

(Action / Effect)
As described above, the actions of a worker (such as a doctor, a technician, or a nurse) required for the priming operation of the extracorporeal circulation device 100 are mainly performed by connecting (puncturing) the priming line 46 to the containing bag 44 and the controller. 14 power switches 16 are only turned on. Thereafter, a priming operation is automatically performed on the extracorporeal circulation device 100.

  The physician can leave the extracorporeal circuit 30 or the like and cannulate the patient's blood vessel (cannulation) or make other preparations. The engineer can also prepare various medical instruments and the like away from the extracorporeal circuit 30 and the like. The nurse can also prepare various chemicals and the like away from the extracorporeal circuit 30 and the like.

  According to the extracorporeal circulation device 100, the operator does not need to check whether the priming fluid is filled in the extracorporeal circulation circuit, and waits for the priming fluid to be filled in the extracorporeal circulation circuit. There is also no need to drive the device. In the extracorporeal circulation device 100, the driving device 12 is automatically driven at a predetermined timing by the detection unit 60 and the controller 14. Therefore, according to the extracorporeal circulation device 100, it is possible to efficiently perform the priming operation without requiring human resources as much as possible.

(First modification)
Like the extracorporeal circulation device 101 shown in FIG. 11, the region 36 where the detection unit 60 is disposed is above the centrifugal pump 10 in the gravity direction in the extracorporeal circulation circuit 30 and is more gravitational than the artificial lung 20. It may be a region below the direction.

  Also in this modified example, the region 36 is located above the centrifugal pump 10 in the extracorporeal circulation circuit 30 in the gravitational direction and below the air discharging unit 50 in the gravitational direction. Also with this configuration, the same operations and effects as those of the above-described embodiment can be obtained.

(Second modification)
In the extracorporeal circulation device 102 shown in FIG. 12, the region 36 is located closer to the air discharge unit 50 than in the case of the above-described embodiment. Also in this modified example, the region 36 is located above the centrifugal pump 10 in the extracorporeal circulation circuit 30 in the gravitational direction and below the air discharging unit 50 in the gravitational direction. Also with this configuration, the same operations and effects as in the above-described embodiment can be obtained.

(Third Modification)
In the extracorporeal circulation device 103 shown in FIG. 13, the region 36 is located in the first path 32. The region 36 is located above the centrifugal pump 10 in the extracorporeal circulation circuit 30 in the gravity direction and below the artificial lung 20 in the gravity direction.

  Also in this modified example, the region 36 is located above the centrifugal pump 10 in the extracorporeal circulation circuit 30 in the gravitational direction and below the air discharging unit 50 in the gravitational direction. Also with this configuration, the same operations and effects as those of the above-described embodiment can be obtained.

(Fourth modification)
In the extracorporeal circulation device 104 shown in FIG. 14, the region 36 is located in the first path 32. The region 36 is located above the artificial lung 20 in the extracorporeal circuit 30 in the gravitational direction and below the air discharging unit 50 in the gravitational direction.

  Also in this modified example, the region 36 is located above the centrifugal pump 10 in the extracorporeal circulation circuit 30 in the gravitational direction and below the air discharging unit 50 in the gravitational direction. Also with this configuration, the same operations and effects as those of the above-described embodiment can be obtained.

  Although the embodiment and each modification based on the present invention have been described above, the embodiment and each modification disclosed this time are illustrative in all points and are not restrictive. The technical scope of the present invention is defined by the terms of the claims, and is intended to include any modifications within the scope and meaning equivalent to the terms of the claims.

  DESCRIPTION OF SYMBOLS 10 Centrifugal pump, 12 Drive apparatus, 14 Controller, 16 Power switch, 20 Artificial lung, 30 Extracorporeal circulation circuit, 32 1st path | route, 33 Blood removal opening | mouth, 34 2nd path | route, 35 Blood return opening | mouth, 36 area | region, 40 Priming liquid Introducing section, 42 priming liquid, 44 storage bag, 46 priming line, 50 air discharge section, 52 hydrophobic filter, 54 storage case, 56 open / close cock, 58 discharge line, 60 detection section, 62 oxygen tank, 64 battery, 66 heat Exchanger, 68 platform, 72, 74 cannula, 82 general artery, 84 general vein, 100, 101, 102, 103, 104 extracorporeal circulation device, AR1, AR2, AR4, AR5, AR6, AR7, AR8, AR9, DR1, DR2 arrow.

Claims (4)

An extracorporeal circulation device used for extracorporeal circulation of blood after a priming operation has been performed,
A pump unit driven by a drive device;
A blood processing unit disposed above the pump unit in the direction of gravity;
An extracorporeal circuit that is annularly formed and communicates with the pump unit and the blood processing unit;
A priming fluid introduction section connected to the extracorporeal circulation circuit for introducing a priming fluid into the extracorporeal circulation circuit;
An air discharge unit connected to the extracorporeal circuit and disposed above the blood treatment unit in the direction of gravity;
The priming liquid introduced into the extracorporeal circuit from the priming liquid introduction part is above the pump part in the extracorporeal circuit and in the gravitational direction below the air discharge part. A detection unit that detects that the region has been reached,
When the priming operation is performed,
By introducing the priming liquid into the extracorporeal circuit from the priming liquid introduction part, the air in the extracorporeal circuit is discharged outside through the air discharge part,
The drive device drives the pump unit after a predetermined time has elapsed since the detection unit has detected that the priming liquid has reached the region,
The pump unit circulates the priming liquid in the extracorporeal circuit,
The air remaining in the extracorporeal circuit reaches the blood treatment unit by the priming liquid circulating in the extracorporeal circuit ,
A part of the air that has reached the blood processing unit is discharged from the blood processing unit to the outside of the blood processing unit without going through the extracorporeal circuit.
Extracorporeal circulation device. The pump unit is a centrifugal pump capable of sending liquid by centrifugal force.
The extracorporeal circulation apparatus according to claim 1. The blood processing unit is an artificial lung that removes carbon dioxide from blood and adds oxygen to blood.
The extracorporeal circulation apparatus according to claim 1 or 2. A method of priming an extracorporeal circulation device used for extracorporeal circulation of blood,
The extracorporeal circulation device is
A pump unit driven by a drive device;
A blood processing unit disposed above the pump unit in the direction of gravity;
An extracorporeal circuit that is annularly formed and communicates with the pump unit and the blood processing unit;
A priming fluid introduction section connected to the extracorporeal circulation circuit for introducing a priming fluid into the extracorporeal circulation circuit;
An air discharge unit connected to the extracorporeal circuit and disposed above the blood treatment unit in the direction of gravity;
The priming liquid introduced into the extracorporeal circuit from the priming liquid introduction part is above the pump part in the extracorporeal circuit and in the gravitational direction below the air discharge part. A detection unit for detecting that the region has been reached,
By introducing the priming liquid into the extracorporeal circuit from the priming liquid introduction section, whereby the air in the extracorporeal circuit is discharged to the outside through the air discharge section;
The drive unit drives the pump unit after a predetermined time has elapsed since the detection unit has detected that the priming liquid has reached the region,
The pump unit circulates the priming liquid in the extracorporeal circuit,
The air remaining in the extracorporeal circuit reaches the blood treatment unit by the priming liquid circulating in the extracorporeal circuit ,
A part of the air that has reached the blood processing unit is discharged from the blood processing unit to the outside of the blood processing unit without going through the extracorporeal circuit.
Priming method for extracorporeal circulation device.

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