JP5970706B2 - Pet taste improver - Google Patents

Description

  The present invention relates to a pet taste improver and a method for using the same. Specifically, the present invention relates to a powdery palatability improver that can handle both powders and tablets.

It is extremely difficult to administer medicines and supplements to pets such as dogs and cats because pets often recognize them as foreign substances and resist them.
Therefore, a pet palatability improver for increasing the palatability of drugs and supplements has been proposed.
Traditionally, preference improvers that have been developed for drugs and supplements were mainly jerky types. However, since the jerky type has hard physical properties, it breaks when a large tablet is embedded, and there is a problem that it cannot be used for powders such as powders.
There has also been proposed an attempt to improve the palatability of tablets by embedding tablets and capsules in a solid carrier made of edible materials. For example, Patent Document 1 describes an edible drug carrier that is manufactured from the same material as that of a pet food and has the same shape as that of a pet food and includes a drug container. However, the method of using such an edible drug carrier also has problems that there are limitations on the shape and size of tablets that can be used, and that powdered products such as powders cannot be used.

JP2011-224000

  Therefore, as a result of intensive studies to solve the above problems, the present inventors, as a result, a powder-like preference agent that can be used for both tablets and powders by blending pregelatinized starch and oil into a preference raw material such as a powder extract. To develop the present invention.

That is, the present invention provides the following.
(1) (i) starchy raw material, (ii) oil and fat selected from powdered oil and fat and solid oil and fat, and (iii) a pet taste improver comprising a powder extract,
(I) The starchy raw material is contained in an amount of 15 to 50% by mass relative to the total amount of the pet taste improver,
60-100% by mass of the starchy raw material is pregelatinized starch,
(Ii) 10 to 200 parts by mass of fats and oils are contained with respect to 100 parts by mass of the starchy raw material when the fats and oils are powdered fats and oils, or 5 to 100 parts by mass of the starchy raw materials when the fats and oils are solid fats and oils. 100 parts by weight, and (iii) 10 to 250 parts by weight of the powder extract is contained with respect to 100 parts by weight of the starchy raw material,
The pet taste improver.
(2) A method of administering powder medicine to pets (excluding humans), wherein the powder medicine and the pet palatability improver described in (1) above are a ratio of the powder powder mass a and the palatability improver mass b. a: b = 1: 1 to 3 are administered, and the method is administered.
(3) A method of administering a solid preparation to pets (excluding humans), wherein water and the pet palatability improver according to (1) are mixed with water mass c and palatability improver mass d. The method according to claim 1, wherein the mixture is mixed at a ratio c: d = 1: 2 to 5 to form a clay-like composition, and a solid agent is wrapped with the composition and administered to a pet (excluding humans).

  The present invention is effective in improving the palatability of powdered medicines by blending oils and fats and having physical properties that are difficult to remove even in powder form and difficult to adhere to the oral cavity. Further, in the present invention, by adding a pregelatinized starch, when it is added to water, it becomes an elongated clay, so that tablets of any size can be wrapped, and it is effective in improving the tablet's palatability.

  In the present invention, a pet refers to a pet animal, which is an animal raised as a target of fun. Pets do not include humans. The animal is preferably a mammal. Examples of pets include dogs and cats.

  In the present invention, palatability is an indicator of whether or not a pet likes to eat, and can be determined, for example, by whether or not a pet eats spontaneously within a limited time.

  In the present invention, powdery medicine means powdery medicines and supplements. Powders include powders, granules, tablets, pills and foods that are pulverized into a powder form.

  In the present invention, the solid agent means a solid drug and supplement. Solid preparations include tablets, capsules, pills, foods and the like with certain shapes.

  The starch-based raw material used in the present invention can be used without particular limitation as long as it contains starch as a main component, wheat flour, barley flour, corn flour, wheat flour, rye flour, oat flour, rice flour, etc. Potato starch, wheat starch, sweet potato starch, tapioca starch, starch such as corn starch, and processed starches using these as raw materials can be used, and it is preferable to use 1 to 3 of these in combination.

In the pet palatability improver of the present invention, the starchy raw material is contained in an amount of 15 to 50% by mass, preferably 23 to 47% by mass, based on the total amount of the pet palatability improver. If it is less than 15% by mass, it is difficult to enclose the solid agent when it is hydrated. When it exceeds 50% by mass, it is unsuitable because it sticks to the oral cavity and is difficult to swallow when administered in a mixture with a powder.
Moreover, 60-100 mass% of the said starch raw material, Preferably 80-100 mass% is pregelatinized starch. If it is less than 60% by mass, the dough is difficult to be stretched when it is hydrated, which is not suitable.

  As fats and oils used in the present invention, vegetable oils such as palm oil, rapeseed oil, soybean oil and corn oil, animal oils such as beef tallow, chicken fat and pork fat can be used, and in the form of powdered fat or solid fat Can be used. Powdered fats and oils are those obtained by adding proteins, sugars and emulsifiers to the fats and spraying them into powders, and those having a lipid content of 50 to 80% can be used. Moreover, solid fats and oils are fats and oils which are solid at normal temperature, for example, shortening, margarine, etc. are mentioned. It is preferable to use 1 to 3 types of fats and oils in combination.

  In the palatability improver for pets of the present invention, the blending ratio of fats and oils is 10 to 200 parts by weight, preferably 60 to 100 parts by weight for starchy raw materials in powdered fats and oils. 120 parts by mass. If it is less than 10 parts by mass, it is unsuitable because it sticks to the oral cavity and is difficult to swallow when it is mixed with powdered medicine. When the amount exceeds 200 parts by mass, it is difficult to encapsulate the solid agent when water is added. In solid fat, it is 5-100 mass parts with respect to 100 mass parts of starchy raw materials, Preferably it is 20-40 mass parts with respect to 100 mass parts of starchy raw materials. If it is less than 5 parts by mass, it is unsuitable because it sticks to the oral cavity and is difficult to swallow when it is mixed with a powdered drug, and it is not suitable because it cannot be mixed with other raw materials uniformly.

  The powder extract used in the present invention is not particularly limited as long as it is a powdery extract used in conventional pet foods. For example, birds such as chickens, ducks, quails, turkeys, cows, pigs, horses, sheep , Powdered livestock extracts made from rabbits, sardines, tuna, bonito, mackerel, Thai, flounder, salmon, trout, crab, shrimp, squid, octopus etc. A powdery yeast extract made from beer yeast, torula yeast or the like can be used.

  In the pet taste improver of the present invention, the blending ratio of the powder extract is 10 to 250 parts by mass with respect to 100 parts by mass of the starchy raw material. If the amount is less than 10 parts by mass, the palatability is not improved, so that it is unsuitable. If the amount exceeds 250 parts by mass, it is not suitable because it is sticky when water is added and the solid agent is not easily wrapped.

The palatability improver for pets of the present invention can use saccharides, celluloses, dextrins and vegetable powders, fruit powders, milk powder, etc. as other raw materials, and it is preferable to use 1 to 3 of these components in combination. .
In the pet taste improver of the present invention, the blending ratio of the other raw materials is 0 to 200 parts by mass with respect to 100 parts by mass of the starchy raw material. When the amount exceeds 200 parts by mass, it is difficult to wrap the tablet when water is added.

  When used for powder medicine, the pet taste improver of the present invention may be administered in a ratio a: b = 1: 1 to 3 between the mass a of the powder medicine and the mass b of the taste improver. it can.

  The pet taste improver of the present invention, when used as a solid preparation, is a clay composition obtained by mixing at a ratio c: d = 1: 2 to 5 of the mass c of water and the weight d of the taste improver. Can be administered by wrapping a solid in the composition.

The palatability improver for pets of the present invention is produced by weighing and mixing raw materials, granulating water as a binder using a granulator such as a fluidized bed granulator, and then drying.
As for the fluidized bed granulator, any one of the generally observed fluidized bed granulator, the stirred fluidized bed granulator, and the rolling fluidized bed granulator can be used without any particular limitation.
Specifically, granulation is performed under the following granulation conditions. As a fluidized bed granulator, 30 kg of all raw materials other than water are introduced into a flow coater FLO-30 (Freund Sangyo Co., Ltd.) and premixed for 4 to 10 minutes. After the pre-mixing is completed, the spray time of 20 to 60 seconds and the shaking time of 2 to 10 seconds are repeated, and the target total amount of water (10 l) is sprayed little by little. In some cases, intermediate drying is set for several minutes. At this time, the supply air temperature is 60 to 85 ° C., and the water addition rate is 40 to 350 ml / min. The obtained granulated product was dried at 90 ° C. for 10 minutes.

EXAMPLES Examples will be shown below for specifically explaining the present invention, but the present invention is not limited to the following examples.
Test Example 1 [Production of palatability improver]
The composition of the raw materials of each Example and Comparative Example is as shown in Table 1. In addition, the numerical value in Table 1 shows a mass part. Matsunoline M or Matsunoline A from Matsutani Chemical Co., Ltd. was used as the pregelatinized starch. Dextrins with DE10 or less such as Paindex # 2 and Paindex # 100 were used as dextrin, and KC Flock W-200G manufactured by Nippon Paper Chemicals Co., Ltd. was used as cellulose.
Each raw material was weighed and mixed with powder. Next, the powder mixture was put into a fluidized bed granulator (flow coater FLO-30 type (manufactured by Freund Sangyo Co., Ltd.)) and premixed for 4 to 10 minutes. After pre-mixing is completed, spray the target water (10 l) at an addition rate of 40 to 350 ml / min, repeat spraying time 20 to 60 seconds, shaking time 2 to 10 seconds, and supply air temperature 60 to 85 ° C. Granulated for 60 minutes. The obtained granulated product was dried at 90 ° C. for 10 minutes.

Test Example 2 [Evaluation of physical properties of mouthfeel improver (melted in mouth) and workability during water addition]
About the palatability improvers of Examples 1 to 10 and Comparative Examples 1 to 8 obtained in Test Example 1, B. Melting in mouth when a person takes in powder. Workability (addition amount is as shown in Table 2 below) when water is added to form a viscosity is evaluated by 10 skilled panelists based on Example 1 according to the evaluation criteria shown in Table 3 and averaged. I asked for a point. The results obtained are shown in Table 4 below.

上記表４の結果から、実施例１〜１０では、粉末での物性、加水時の作業性ともに優れた嗜好性向上剤が得られることが確認された。
一方、α化澱粉の割合が澱粉性原材料の６０質量％よりも低い比較例１、澱粉性原材料１００質量部に対し固形油脂の割合が１００質量部より高い比較例２、及び粉末エキスの割合が２００質量部より高い比較例６では粉末での口溶け及び加水時の作業性、特に加水時の作業性が劣っていた。また油脂の割合が低い比較例３及び粉末油脂の割合が２００質量部より多い比較例４では粉末での口溶け及び加水時の作業性、特に粉末での口溶けが劣っていた。さらに澱粉性原材料の割合がペット用嗜好性向上剤の全量に対し５０質量％より高い比較例７では粉末での口溶けが劣っており、１５質量％より低い比較例８では加水時の作業性が劣っていた。

From the result of the said Table 4, in Examples 1-10, it was confirmed that the palatability improver excellent in the physical property in powder and the workability | operativity at the time of water addition is obtained.
On the other hand, Comparative Example 1 in which the proportion of pregelatinized starch is lower than 60% by mass of the starchy raw material, Comparative Example 2 in which the proportion of the solid fat is higher than 100 parts by mass with respect to 100 parts by mass of the starchy raw material, and the proportion of the powder extract is In Comparative Example 6, which is higher than 200 parts by mass, the meltability in the powder and workability at the time of addition, particularly the workability at the time of addition, were inferior. Further, in Comparative Example 3 in which the ratio of fats and oils was low and in Comparative Example 4 in which the ratio of powdered fats and oils was more than 200 parts by mass, meltability in the powder and workability at the time of addition, particularly meltability in the powder was inferior. Furthermore, in Comparative Example 7 in which the proportion of the starchy raw material is higher than 50% by mass with respect to the total amount of the pet taste improver, the powder is poorly melted in the powder, and in Comparative Example 8 lower than 15% by mass, the workability during addition is high. It was inferior.

Test Example 3 [Preference test using animals]
The palatability test was conducted on Example 5 and Example 6 and Comparative Example 5 in which the results of the evaluation of the physical properties (melting in the mouth) and the workability during water addition were good overall in Test Example 2 above. went.
In the palatability test, 10 dogs and 15 cats were used, and it was evaluated whether the test samples were fed once a day and eaten for 10 minutes. The test was conducted for 2 days and the number of statements was counted. Test samples include A. Powder only, B. A mixture of powdered medicine and invention product in a mass ratio of 1: 2, C.I. Tablets only Four types of tablets were used, which were kneaded with water and made into a clay. In addition, chondroitin-containing supplements were used for both powders and tablets. The results are shown below.

・加水して粘土状にし、錠剤を包み込んで与えた場合

Test result (dog)
・ When mixed with powder and given as powder

・ When water is added to make clay, and tablets are wrapped

・加水して粘土状にし、錠剤を包み込んで与えた場合

上記表４の結果から、実施例の嗜好性向上剤についてはイヌ及びネコのいずれにおいても優れた嗜好性が得られることが確認された。 Test result (cat)
・ When mixed with powder and given as powder

・ When water is added to make clay, and tablets are wrapped

From the results of Table 4 above, it was confirmed that excellent palatability was obtained in both dogs and cats for the palatability improvers of the examples.

Claims (1)

A method of administering a solid agent to a pet (excluding humans),
Water and
(I) a starchy raw material, (ii) an oil and fat selected from powdered oil and fat and solid oil and fat, and (iii) a palatability improver comprising a powder extract,
(I) The starchy raw material is contained in an amount of 15 to 50% by mass relative to the total amount of the pet taste improver,
60-100% by mass of the starchy raw material is pregelatinized starch,
(Ii) 10 to 200 parts by mass of fats and oils are contained with respect to 100 parts by mass of the starchy raw material when the fats and oils are powdered fats and oils, or 5 to 100 parts by mass of the starchy raw materials when the fats and oils are solid fats and oils. 100 parts by weight, and (iii) 10 to 250 parts by weight of the powder extract is contained with respect to 100 parts by weight of the starchy raw material,
The palatability improver for pets,
Ratio c of water mass c and mass d of said palatability improver c: d = 1: 2 to 5 are mixed to form a clay-like composition. ), Wherein said method is administered .