JP6086757B2 - Aerosol insecticide - Google Patents

Description

  The present invention relates to an aerosol type insecticide.

  Conventionally, in order to control insects such as cockroaches, ticks, fleas, mosquitoes, flies, etc., it has been common to treat closed spaces such as indoors with a space treatment agent containing active ingredients (insecticidal ingredients). Has been done. As a space treatment agent used for such a purpose, a smoke type insecticide, an aerosol type insecticide, etc. are common.

In recent years, pyrethroid compounds and oxadiazole compounds have become mainstream as active ingredients blended in space treatment agents for the purpose of cockroach control. Among them, pyrethroid compounds are widely used because they act on the nervous system of cockroaches, have an excellent knockdown effect, and have low toxicity to the human body.
Recently, however, cockroaches having a strong resistance to these drugs (pyrethroid-resistant cockroaches) have been generated along with the extensive use of pyrethroid compounds, making it difficult to control.

  An oxadiazol-based compound, 5-methoxy-3- (2-methoxyphenyl) -1,3,4-oxadiazol-2 (3H) -one (generic name: methoxadiazone) is against pyrethroid-resistant cockroaches. It is known to exhibit an excellent insecticidal effect. For example, Patent Document 1 discloses a fumigant for pest control using methoxadiazone.

However, since methoxadiazone is poorly soluble, there are limited solvents that can be used as aerosol pesticides.
Known solvents that can dissolve methoxadiazone include propylene carbonate, N-alkyl-pyrrolidone, γ-butyrolactone, dimethyl carbonate, diethyl carbonate, methyl lactate, ethyl lactate, and butyl lactate. For example, Patent Document 2 discloses an insecticide containing methoxadiazone and propylene carbonate.

Japanese Patent Laid-Open No. 9-165307 Japanese Patent No. 2959995

By the way, methoxadiazone has a strong unpleasant odor and a unique irritation. Therefore, after using an insecticide containing methoxadiazone, it sometimes felt remarkably uncomfortable.
When propylene carbonate is used as a solvent as described in Patent Document 2, propylene carbonate itself has a lower odor than other solvents such as N-alkyl-pyrrolidone, but reduces the unpleasant odor and irritation of methoxadiazone. Was difficult.
In particular, in the case of all-injection aerosol pesticides, odor and irritation tend to be enhanced when methoxadiazone is injected and atomized.

  The present invention has been made in view of the above circumstances, and an object of the present invention is to provide an aerosol-type insecticide that has a high insecticidal effect and maintains an unpleasant odor and irritation without causing an unnecessary scent.

  As a result of intensive studies, the present inventors have found that by combining a specific essential oil with methoxadiazone and propylene carbonate, the unpleasant odor and irritation derived from methoxadiazone can be effectively reduced, and the present invention has been completed.

That is, this invention has the following aspects.
[1] An aerosol type insecticide containing the following components (A) to (C).
Component (A): 5-methoxy-3- (2-methoxyphenyl) -1,3,4-oxadiazol-2 (3H) -one.
(B) component: Propylene carbonate.
(C) component: 1 or more types chosen from the group which consists of grapefruit oil, rose oil, Gaiakwood oil, eucalyptus oil, orange oil.
[2] The content of the component (B) is 250 to 1500 parts by mass with respect to 100 parts by mass of the component (A), and the content of the component (C) is 0.001 to 1 part by mass. The aerosol type insecticide according to [1].

  ADVANTAGE OF THE INVENTION According to this invention, the insecticidal effect is high and can provide the aerosol type insecticide which the suppression of an unpleasant odor and irritation | stimulation continues without making an unnecessary fragrance feel.

Hereinafter, the present invention will be described in detail.
The aerosol type insecticide of the present invention (hereinafter simply referred to as “insecticide”) contains the following components (A) to (C).

<(A) component>
Component (A) is 5-methoxy-3- (2-methoxyphenyl) -1,3,4-oxadiazol-2 (3H) -one, which is known by the general name of methoxadiazone.
The component (A) is an active ingredient (insecticidal ingredient) that exterminates insects such as flies, mosquitoes and cockroaches. Among them, an excellent insecticidal effect is exhibited against cockroaches, particularly pyrethroid resistant cockroaches.

  (A) 0.1-5.5 mass% is preferable in 100 mass% of insecticides, and, as for content of a component, 0.8-3.5 mass% is more preferable. If content of (A) component is 0.1 mass% or more, an insecticidal effect can be improved more. On the other hand, if the content of the component (A) is 5.5% by mass or less, the effect when the component (C) described later is used is further enhanced, and the unpleasant odor and irritation of the component (A) are further suppressed. it can. In addition, since the component (A) is an oily component, it may become cloudy or lose its gloss when adhered to a large amount of floor or glass in the room, but the content of the component (A) is 5.5 mass. If it is less than%, it is difficult to remain in the room, so the room is difficult to get dirty.

  Moreover, although mentioned later in detail, when using the insecticide of this invention as a total injection type aerosol type insecticide, content of (A) component is 0.2-2. 7g is preferable and 0.4-1.6g is more preferable.

<(B) component>
Component (B) is propylene carbonate.
The component (B) acts as a solvent for the component (A). Moreover, the unpleasant odor and irritation | stimulation of (A) component can be remarkably and continuously reduced by using together with (C) component mentioned later.

  (B) As for content of a component, 250-1500 mass parts is preferable with respect to 100 mass parts of (A) component, and 300-1000 mass parts is more preferable. If content of (B) component is 250 mass parts or more, since the (A) component and (C) component are fully compatible, the reduction effect of an unpleasant odor and irritation | stimulation can be maintained more. By the way, since (B) component is an oil-based component, when it adheres abundantly to an indoor floor, glass, etc. similarly to (A) component, cloudiness may arise or gloss may lose | disappear. In particular, when an insecticide is used as a full spray aerosol type insecticide, many components (B) tend to adhere to the room. If the content of the component (B) is 1500 parts by mass or less, even if the insecticide of the present invention is used as a full-injection aerosol type insecticide, it is difficult to remain in the room, so that the room is difficult to get dirty.

<(C) component>
Component (C) is one or more essential oils selected from the group consisting of grapefruit oil, rose oil, Gaiakwood oil, eucalyptus oil, and orange oil.
Component (C) is a component that remarkably and continuously reduces the unpleasant odor and irritation of component (A) when used in combination with component (B).

Grapefruit oil is an essential oil (essential oil) collected from the peel and / or fruit of grapefruit by a pressing method.
Examples of main components contained in grapefruit oil include limonene, octanal, decanal, and nootkaton.
A commercially available product can be used as the grapefruit oil.

Rose oil is an essential oil obtained by distilling rose petals by steam distillation.
Examples of main components contained in rose oil include phenylethyl alcohol, geraniol, citronellol, linalool, and nerol.
A commercially available product can be used as the rose oil.

Gaiakwood oil is an essential oil obtained by distilling trunks and / or wood chips by a steam distillation method.
Examples of main components contained in Gaiakwood oil include guaiacol (guaiacol) and brunesole.
A commercially available product can be used as the Gaiac wood oil.

Eucalyptus oil is an essential oil obtained by distilling eucalyptus leaves by a steam distillation method.
Examples of main components contained in eucalyptus oil include 1,8-cineole, α-pinene, and camphene.
A commercially available product can be used as the eucalyptus oil.

Orange oil is an essential oil collected by pressing from orange peel and / or fruit.
Examples of main components contained in orange oil include limonene, octanal, nonanal, and decanal.
A commercially available product can be used as the orange oil.

  As for content of (C) component, 0.001-1 mass part is preferable with respect to 100 mass parts of (A) component, and 0.005-0.5 mass part is more preferable. If content of (C) component is 0.001 mass part or more, the reduction effect of an unpleasant odor and irritation | stimulation can be maintained more. On the other hand, even if the content of the component (C) exceeds 1 part by mass, the unpleasant odor and irritation of the component (A) can be suppressed, but when the content of the component (C) increases, the component (C) is derived. For example, when the insecticide of the present invention is used as a spray-injection aerosol-type insecticide, the fragrance derived from the component (C) tends to remain even if the room is ventilated, and the insecticide is used. May be felt for a long time. Therefore, the content of the component (C) is preferably 1 part by mass or less.

The insecticide of the present invention is an aerosol-type insecticide in which a liquid agent (insecticide liquid agent) containing the components (A), (B), and (C) and a propellant are filled in an aerosol can or a pressure-resistant container. It is. The spraying method is not particularly limited, and it may be a spray type in which the contents of the aerosol can are directly sprayed toward the target pests, or almost all of the contents of the pressure vessel can be operated indoors with one operation (opening the valve, etc.). A full-quantity injection type in which spraying (spreading) is performed in a closed space such as the above.
The spray type is particularly suitable for use against dwarf pests and flying pests that move quickly. On the other hand, the all-injection type is particularly suitable for spreading insecticidal components to every corner of the room.
Hereinafter, an insecticide sprayed by the spray method is particularly referred to as a “spray aerosol type insecticide”, and an insecticide sprayed by the total amount spray method is particularly referred to as a “full amount aerosol type insecticide”.

  The pesticide solution may contain a solvent other than the component (B). Examples of other solvents include ethanol (including anhydrous ethanol), methanol, acetone, glycol ethers (ethylene glycol and derivatives thereof, diethylene glycol and derivatives thereof, other alkylene glycols and derivatives thereof), dimethyl carbonate, and N-methyl. Examples include pyrrolidone, N-ethylpyrrolidone, γ-butyrolactone, methyl lactate, ethyl lactate, dibutyl lactate, isoparaffin, normal paraffin, kerosene, and water.

Examples of the propellant include liquefied gas (dimethyl ether, liquefied petroleum gas, chlorofluorocarbon, hydrochlorofluorocarbon, hydrofluorocarbon, hydrofluoroolefin, etc.), compressed gas (carbon dioxide gas, nitrogen gas, nitrous oxide, etc.) and the like.
The blending ratio of the insecticide and the propellant is appropriately determined in consideration of jetting characteristics and safety. For example, the mass ratio represented by the insecticide / propellant is preferably 1/99 to 90/10, and more preferably 10/90 to 50/50.

In addition, the insecticide of the present invention includes an active ingredient (insecticide component) other than the component (A), a stabilizer, a rust inhibitor, an emulsifier, a dispersant, an excipient, as long as the effects of the present invention are not impaired. You may mix | blend additives, such as a pigment | dye and a fragrance | flavor, as needed.
Examples of the active ingredient other than the component (A) include insecticidal active ingredients such as pyrethroid compounds such as permethrin and phenothrin, neonicotinoids and organic phosphorus compounds, and insect growth inhibitors.

When the pesticide of the present invention is used as a full spray aerosol pesticide, the pesticide is sprayed so that the amount of the component (A) sprayed indoors (methoxadiazone spray amount) is 3 mg or more per 1 m ^{3 of the} room. It is preferably 6 mg or more, more preferably 9 mg or more. If the amount of methoxadiazone sprayed is ³ mg or more per 1 m ^{3 of} room (about 7 mg or more per 1 m ² in terms of area), a high insecticidal effect may be exerted on many cockroaches including pyrethroid resistant cockroaches. it can. The methoxadiazone application amount is preferably 150 mg or less, more preferably 100 mg or less per 1 m ^{3 of} the room in consideration of safety and economic efficiency.

  On the other hand, when the insecticide of the present invention is used as a spray aerosol insecticide, the amount of the component (A) sprayed toward the target pest (methoxadiazone spray amount) is 0.1 mg or more per time. It is preferable to spray an insecticide on the surface, more preferably 1 mg or more. When the injection amount of methoxadiazone is 0.1 mg or more per shot, a high insecticidal effect can be exhibited against many cockroaches including pyrethroid resistant cockroaches. Further, the methoxadiazone injection amount is preferably 500 mg or less, more preferably 250 mg or less, in consideration of safety and economy.

  The filling amount of the insecticide into the pressure-resistant container is appropriately determined so that the methoxadiazone application amount and the methoxadiazone injection amount are within the above ranges. Moreover, when using an insecticide indoors, it determines suitably according to the magnitude | size of the indoor processed.

Moreover, in this invention, although (C) component is injected with (A) component which is an active ingredient, unpleasant odor and irritation | stimulation can be suppressed, but if (C) component is easy to diffuse, unpleasant odor And more effectively suppress irritation. In particular, in the case of a full-injection aerosol type insecticide, from the viewpoint of the insecticidal effect, it is desired that the component (A) is distributed to every corner of the room. At this time, the component (C) is also spread to every corner of the room. By traveling, it is possible to more effectively suppress unpleasant odors and irritation.
In the case of a full-amount aerosol type insecticide, in order to spread the component (A) and the component (C) to every corner of the room, the insecticide should have a particle state with an average particle size of 50 μm or less, more preferably an average particle size. Is preferably dispersed indoors in a particle state of 15 μm or less.
On the other hand, in the case of a spray aerosol type insecticide, in order to facilitate the diffusion of the component (C), the insecticide is sprayed in a particle state having an average particle size of 100 μm or less, more preferably in a particle state having an average particle size of 50 μm or less. It is preferable to do this.
The average particle diameter of the insecticide at the time of spraying can be adjusted by the blending ratio of the insecticide and the propellant, the nozzle hole diameter of the pressure vessel filled with the insecticide, the injection pressure, and the like.

The insecticide of the present invention can be used indoors or outdoors, but is used mainly indoors, particularly when the insecticide of the present invention is used as a full-injection aerosol type insecticide. The room to be processed is a space that can be sealed, and examples thereof include indoors and vehicles.
On the other hand, when the insecticide of the present invention is used as a spray aerosol insecticide, it may be used indoors or outdoors. When used indoors, the room to be processed may not be sealable or may be a sealable space.

  Examples of the insect pests to which the insecticide of the present invention is applied include cockroaches such as German cockroaches, black cockroaches, cockroaches, American cockroaches, flying cockroaches, etc .; Dust mites; dust mites such as nymph dust mites; claw mites such as southern mites Flies such as butterflies; lice; bed bugs; moths; high insecticidal effects against clothing pests such as moths, moths and cutworms, and their practicality is extremely high.

According to the insecticide of this invention demonstrated above, since (A) component is contained, an insecticidal effect is high. In particular, it exhibits a high insecticidal effect against pyrethroid resistant cockroaches.
In addition, since the insecticide of the present invention contains the component (C) in addition to the component (B), the unpleasant odor and irritation of the component (A) can be reduced without causing an unnecessary scent, and the reduction. The effect can be sustained.

  EXAMPLES The present invention will be specifically described below with reference to examples, but the present invention is not limited to these examples.

[Raw materials]
As the component (A), methoxadiazone was used.
As the component (B), propylene carbonate was used. Moreover, 1-methyl-2-pyrrolidone was used as a comparative product (component (B ′)) of component (B).
As the component (C), grapefruit oil, orange oil, rose oil, Gaiakwood oil, and eucalyptus oil containing the main components shown in Table 1 were used. In addition, peppermint oil and spearmint oil containing main components shown in Table 1 were used as comparative products (component (C ′)) of component (C).
Absolute ethanol was used as another solvent.
Dimethyl ether was used as a propellant.

[Example 1]
<Preparation of all-injection aerosol type insecticide>
An insecticide was prepared by mixing 0.8 g of methoxadiazone, 5 g of propylene carbonate, 0.00008 g of rose oil, and a balance amount of absolute ethanol as another solvent. This was filled in a container of Mist Balsan (manufactured by Lion Corporation) and subjected to the following evaluation test.
Specifically, the obtained insecticide was placed in a pressure resistant container, 35 g of dimethyl ether as a propellant was pressure-filled and sealed, and an injection device was attached to obtain a full-injection aerosol-type insecticide. The following evaluation was performed about the obtained all-injection aerosol type insecticide. The results are shown in Table 2.
The “balance” is an amount by which the total volume (total amount) of the aerosol spray insecticide is 50 g.

<Evaluation>
(No unpleasant odor)
A full-injection aerosol type insecticide was placed in the center of the floor of a 32 m ³ sealed room, and a button was pressed to inject the entire amount of the full-injection aerosol type insecticide. Then, it entered the room and sensory evaluation was performed according to the following evaluation criteria.
Next, the room was ventilated at a ventilation rate of 10 times / hour, and the room was entered 15 minutes and 30 minutes after ventilation, and sensory evaluation was performed again according to the following evaluation criteria. Note that the ventilation rate is the number of times that all the indoor air has been changed during one hour, and the ventilation rate of 10 times / hour means that the indoor air has been changed ten times during one hour. means.
The average value of five panelists was determined, and ◎: 3.5 points to 4.0 points, ○: 3.0 points to less than 3.5 points, Δ: 2.0 points to less than 3.0 points, ×: The score was 1.0 point or higher and lower than 2.0 point, and the absence of unpleasant odor was evaluated.
Evaluation criteria;
4 points: No unpleasant odor.
3 points: Does not feel unpleasant odor.
2 points: A slight unpleasant odor is felt.
1 point: An unpleasant odor is felt.

(No stimulation)
A full-injection aerosol type insecticide was placed in the center of the floor of a 32 m ³ sealed room, and a button was pressed to inject the entire amount of the full-injection aerosol type insecticide. Then, it entered the room and sensory evaluation was performed according to the following evaluation criteria.
Next, the room was ventilated at a ventilation rate of 10 times / hour, and the room was entered 15 minutes and 30 minutes after ventilation, and sensory evaluation was performed again according to the following evaluation criteria.
The average value of five panelists was determined, and ◎: 3.5 points to 4.0 points, ○: 3.0 points to less than 3.5 points, Δ: 2.0 points to less than 3.0 points, ×: The score was 1.0 point or more and less than 2.0 point, and the absence of stimulation was evaluated.
Evaluation criteria;
4 points: I do not feel irritation.
3 points: I do not feel much stimulation.
2 points: I feel some stimulation.
1 point: I feel irritation.

(No scent)
A full-injection aerosol type insecticide was placed in the center of the floor of a 32 m ³ sealed room, and a button was pressed to inject the entire amount of the full-injection aerosol type insecticide. Then, it entered the room and sensory evaluation was performed according to the following evaluation criteria.
Next, the room was ventilated at a ventilation rate of 10 times / hour, and the room was entered 15 minutes and 30 minutes after ventilation, and sensory evaluation was performed again according to the following evaluation criteria.
The average value of five panelists was determined, and ◎: 3.5 points to 4.0 points, ○: 3.0 points to less than 3.5 points, Δ: 2.0 points to less than 3.0 points, ×: The fragrance was evaluated as 1.0 or more and less than 2.0.
Evaluation criteria;
4 points: The fragrance derived from the component (C) is not felt so much.
3 points: A slight scent derived from the component (C).
2 points: A fragrance derived from component (C) is felt.
1 point: The scent derived from the component (C) is very felt.

[Examples 2 to 9, Comparative Examples 1 to 4]
Except that the insecticide was prepared in accordance with the composition shown in Tables 2 and 3, a full spray aerosol type insecticide was obtained in the same manner as in Example 1. The obtained all-injection aerosol type insecticide was evaluated in the same manner as in Example 1. The results are shown in Tables 2 and 3.

As is apparent from Tables 2 and 3, the all-injection aerosol type insecticides obtained in Examples 1 to 9 exhibited the masking effect by the (B) component and (C) component, I was able to reduce irritation. Moreover, the fragrance derived from the component (C) was hardly felt.
In particular, Examples 1 to 7, in which the content of the component (B) is 250 parts by mass or more and the content of the component (C) is 0.001 parts by mass or more with respect to 100 parts by mass of the component (A). The all-injection aerosol-type insecticide obtained in No. 9 was able to sustain the effect of reducing unpleasant odor and irritation.
Thus, the all-injection aerosol type insecticides obtained in Examples 1 to 9 were able to reduce unpleasant odors and irritation over a long period of time without causing an unnecessary scent.

On the other hand, although the total amount injection type aerosol insecticide obtained in Comparative Examples 1 and 2 using peppermint oil or spearmint oil instead of the component (C) was able to reduce the unpleasant odor immediately after entering the room, This mitigation effect could not be sustained. Moreover, irritation could not be reduced.
(B) Instead of the component, the all-injection aerosol-type insecticide obtained in Comparative Example 3 using 1-methyl-2-pyrrolidone was able to reduce the unpleasant odor and irritation immediately after entering the room to some extent, The reduction effect could not be sustained.
(B) Instead of the component, 1-methyl-2-pyrrolidone was used, and the all-injection aerosol-type insecticide obtained in Comparative Example 4 using peppermint oil instead of the component (C) had an unpleasant odor and Irritation could not be reduced.

[Example 10]
<Preparation of spray aerosol insecticide>
An insecticide was prepared by mixing 0.8 g of methoxadiazone, 5 g of propylene carbonate, 0.00008 g of rose oil, and a balance amount of absolute ethanol as another solvent. This was filled in a container of Balsan this one spray (manufactured by Lion Corporation) and subjected to the following evaluation test.
Specifically, the obtained insecticide is placed in an aerosol can, 35 g of liquefied petroleum gas (0.15 mPa / 25 ° C.) is pressure-filled and sealed as a propellant, and a spray aerosol is attached thereto. A type insecticide was obtained.
The “balance” is an amount that causes the content (total amount) of the spray aerosol insecticide to be 50 g.

<Evaluation>
The resulting spray aerosol insecticide was sprayed for 10 seconds indoors. The absence of an unpleasant odor immediately after injection, no irritation, and no fragrance were evaluated according to the same evaluation criteria as in Example 1.
As a result, all results were “「 ”, the masking effect by the component (B) and the component (C) was exhibited, and the unpleasant odor and irritation could be continuously reduced. Moreover, the scent derived from the component (C) was not felt.
Thus, the spray aerosol insecticide obtained in Example 10 was able to reduce unpleasant odor and irritation over a long period of time without causing an unnecessary scent.

Claims (2)

An aerosol-type insecticide containing the following components (A) to (C).
Component (A): 5-methoxy-3- (2-methoxyphenyl) -1,3,4-oxadiazol-2 (3H) -one.
(B) component: Propylene carbonate.
(C) component: 1 or more types chosen from the group which consists of grapefruit oil, rose oil, Gaiakwood oil, eucalyptus oil, orange oil.   The content of the component (B) is 250 to 1500 parts by mass with respect to 100 parts by mass of the component (A), and the content of the component (C) is 0.001 to 1 part by mass. 2. The aerosol type insecticide according to 1.