JP6411733B2 - Hair coloring agent in spray container - Google Patents

Description

  The present invention relates to a hair coloring agent in a spray container in which a hair coloring agent is accommodated in a spray container.

  Conventionally, various hair coloring agents have been proposed in order to change the color of hair to a target color (hereinafter referred to as target color).

  For example, a hair coloring agent for coloring white hair appearing in hair to a target color is generally referred to as white hair dyeing, and is widely used as an appearance mainly for the elderly.

  Such a hair coloring agent is used by directly applying to hair, and the pigment contained in the hair coloring agent is attached to the surface of the hair or impregnated in the hair, so that the color of the hair becomes the target color. It is common to change.

  If an example of the pigment | dye contained in a hair coloring agent is shown, the pigment | dye already exhibiting the target color (henceforth a target color pigment | dye) will be mentioned, for example, before applying to hair.

  According to the coloring agent containing the target color pigment, since the pigment has already exhibited the target color at the time before use, the hair can be quickly colored into the target color.

  Moreover, when paying attention to the dosage form of the hair coloring agent, foams and pastes are widely used.

Japanese Patent Application Laid-Open No. 2012-116829

  However, although the above-mentioned conventional hair coloring agent can quickly dye the target color by containing the target color pigment as described above, an unnecessary hair coloring agent adheres to the scalp. In some cases, a relatively clear pigment mark may be left on the scalp.

  In addition, because the dosage form is foamy or pasty, it is often cumbersome to use, for example, it is necessary to apply it to the hair while extending it with the palm of your hand, or it is necessary to wash or wash your hair after the hair coloring treatment. .

  Therefore, in order to avoid such drawbacks, compounds that exhibit polyphenols and exhibit the target color by oxidative polymerization without using the target color dyes as described above (hereinafter generically referred to as compounds before polymerization). In other words, there is a technique for dyeing hair by binding the produced polyphenols to the hair.

  However, compared with the target color pigment, the coloration with the polyphenol has a problem that the color development speed is slow and it takes time to reach the target color.

  The present invention has been made in view of such circumstances, and does not require a mixing operation on the palm of the user, and more quickly achieves the target color as compared with conventional polyphenol hair coloring agents. Provided is a hair coloring agent in a spray container that can be dyed.

で示される酸化補助剤とを混合した染毛基液に酸化酵素液を混合して、ノズルから噴霧可能に構成し、前記染毛基液は、0.01〜3重量％の前記ポリフェノール構成化合物と、0.001〜0.01重量％の前記酸化補助剤とを含み、前記酸化酵素液は、0.01〜2重量％の酸化酵素を含むと共に、前記噴霧容器内にて区画された２つの収容部に前記染毛基液と前記酸化酵素液とをそれぞれ別個に収容し、前記ノズルの噴霧口は、噴霧した液が互いに交差する角度で配設されており、吹き出した直後に前記染毛基液と前記酸化酵素液とが混合されるように構成したことに特徴を有する。
また、本発明では、噴霧容器入りヘアカラーリング剤であって、互いに酸化重合することによりポリフェノール類を構成するポリフェノール構成化合物と、一般式 [I]：

で示される酸化補助剤とを混合した染毛基液に酸化酵素液を混合して、ノズルから噴霧可能に構成したことを特徴とする噴霧容器入りヘアカラーリング剤であって、前記染毛基液は、0.01〜3重量％の前記ポリフェノール構成化合物と、0.1〜0.2重量％の前記酸化補助剤とを含み、前記酸化酵素液は、0.01〜3重量％の酸化酵素を含むと共に、前記噴霧容器内にて区画された２つの収容部に前記染毛基液と前記酸化酵素液とをそれぞれ別個に収容し、前記ノズルの噴霧口は、噴霧した液が互いに交差する角度で配設されており、吹き出した直後に前記染毛基液と前記酸化酵素液とが混合されるように構成していることに特徴を有する。 In order to solve the above-described conventional problems, the present invention is a hair coloring agent in a spray container, which comprises a polyphenol-constituting compound constituting a polyphenol by oxidative polymerization with each other, and a general formula [I]:

An oxidase enzyme solution is mixed with a hair dye base solution mixed with an oxidizing aid represented by the composition, and is configured to be sprayable from a nozzle, and the hair dye base solution includes 0.01 to 3% by weight of the polyphenol constituent compound, 0.001 to 0.01% by weight of the oxidative auxiliary agent, and the oxidase solution contains 0.01 to 2% by weight of oxidase, and the hair dye group is contained in two housing parts partitioned in the spray container. The liquid and the oxidase liquid are separately stored, and the spray port of the nozzle is disposed at an angle at which the sprayed liquids intersect with each other, and immediately after being blown out, the hair dye base liquid and the oxidase liquid And are configured to be mixed.
Further, in the present invention, a hair coloring agent in a spray container, which comprises a polyphenol-constituting compound constituting a polyphenol by oxidative polymerization with each other, and a general formula [I]:

A hair coloring agent in a spray container, wherein the hair coloring base solution is mixed with an oxidative enzyme solution mixed with an oxidation auxiliary agent represented by The liquid contains 0.01 to 3% by weight of the polyphenol constituent compound and 0.1 to 0.2 % by weight of the oxidative aid, and the oxidase liquid contains 0.01 to 3% by weight of oxidase and the spray container The hair dye base solution and the oxidase solution are separately stored in two storage sections partitioned inside, and the spray ports of the nozzles are arranged at angles at which the sprayed liquids intersect each other. The hair dye base solution and the oxidase solution are mixed immediately after being blown out.

In the present invention, the oxidative auxiliary agent is characterized in that it has a higher substrate binding property to an oxidase contained in the oxidase solution than the polyphenol constituent compound and is not easily oxidized.

In the present invention, the oxidation aid is characterized in that it is catechol, pyrogallol, gallic acid, or a mixture thereof.

In the present invention, the oxidase contained in the oxidase solution is characterized in that it is any one polyphenol oxidase selected from laccase, tyrosinase, and bilirubin oxidase, or two or more polyphenol oxidase mixed enzymes. .

In the present invention, the polyphenol constituent compound is quercetin.

で示される酸化補助剤とを混合した染毛基液に酸化酵素液を混合して、ノズルから噴霧可能に構成し、前記染毛基液は、0.01〜3重量％の前記ポリフェノール構成化合物と、0.001〜0.01重量％又は0.1〜0.2重量％の前記酸化補助剤とを含み、前記酸化酵素液は、0.01〜2重量％又は0.01〜3重量％の酸化酵素を含むと共に、前記噴霧容器内にて区画された２つの収容部に前記染毛基液と前記酸化酵素液とをそれぞれ別個に収容し、前記ノズルの噴霧口は、噴霧した液が互いに交差する角度で配設されており、吹き出した直後に前記染毛基液と前記酸化酵素液とが混合されるように構成したため、使用者による手のひら上での混合作業の必要がなく、しかも、従来のポリフェノール系ヘアカラーリング剤に比して速やかに目的色に染毛することのできる噴霧容器入りヘアカラーリング剤を提供することができる。また、前記染毛基液と前記酸化酵素液は、前記噴霧容器内にて区画された２つの収容部にそれぞれ別個に収容されていることとしたため、噴霧容器内における染毛基液と酸化酵素液との反応を確実に抑制することができる。 According to the present invention, the polyphenol-constituting compounds constituting the polyphenols by oxidative polymerization with each other, and the general formula [I]:

An oxidase enzyme solution is mixed with a hair dye base solution mixed with an oxidizing aid represented by the composition, and is configured to be sprayable from a nozzle, and the hair dye base solution includes 0.01 to 3% by weight of the polyphenol constituent compound, 0.001-0.01 and a weight percent, or 0.1 to 0.2 wt% of the oxidizing aid, the oxidizing enzyme solution, together containing 0.01 to 2 wt%, or 0.01 to 3 wt% of the oxidase in the spray container The hair dye base solution and the oxidase solution are separately stored in two compartments, and the spray port of the nozzle is disposed at an angle at which the sprayed liquid intersects each other, and is blown out. Since the hair dye base solution and the oxidase solution are mixed immediately afterwards, there is no need for mixing work on the palm by the user, and compared to conventional polyphenol hair coloring agents. Spray that can quickly dye the target color It is possible to provide a vessel containing hair coloring agent. In addition, since the hair dye base solution and the oxidase solution are separately stored in two storage sections partitioned in the spray container, the hair dye base solution and the oxidase in the spray container Reaction with a liquid can be suppressed reliably.

In addition, according to the present invention, the oxidation auxiliary agent has a higher substrate binding property to the oxidase contained in the oxidase solution than the polyphenol constituent compound and is less likely to be oxidized. Since the oxidation auxiliary agent can be oxidized prior to the constituent compound and the polyphenol constituent compound can be oxidatively polymerized by the oxidation auxiliary agent, the polyphenol can be synthesized more efficiently and the hair dyeing speed can be improved.

Further, according to the present invention, since the oxidation auxiliary agent is catechol, pyrogallol, gallic acid, or a mixture thereof, the hair dyeing speed can be improved more steadily.

According to the present invention, the oxidase contained in the oxidase solution is any one polyphenol oxidase selected from laccase, tyrosinase, and bilirubin oxidase, or two or more polyphenol oxidase mixed enzymes. The oxidation auxiliary can be efficiently oxidized prior to the polyphenol constituent compound.

In addition, according to the present invention, since the polyphenol constituent compound is quercetin, it is possible to efficiently perform oxidative polymerization by oxidation with an oxidative auxiliary agent, and to have as little discomfort to the hair as possible. Coloring can be applied.

It is explanatory drawing which showed the use condition of the hair coloring agent A with a spraying container which concerns on this embodiment. It is explanatory drawing which showed the structure of the hair coloring agent A with a spray container which concerns on this embodiment.

で示される酸化補助剤とを混合した染毛基液に酸化酵素液を混合して、ノズルから噴霧可能に構成したことを特徴とする噴霧容器入りヘアカラーリング剤を提供するものである。 The present invention relates to a polyphenol-constituting compound constituting a polyphenol by oxidative polymerization with each other, a general formula [I]:

A hair coloring agent in a spray container is provided, wherein the hair dye base solution mixed with the oxidative auxiliary agent is mixed with an oxidase enzyme solution and sprayable from a nozzle.

  The hair coloring agent containing the spray container according to the present embodiment is configured by accommodating the hair coloring agent in the spray container, and the hair coloring agent includes two agents of a hair dye base solution and an oxidase solution. Consists of. The hair coloring agent in the spray container according to the present embodiment mixes the above-mentioned hair dye base solution and the oxidase solution for hair dyeing and attaches them to the hair. In addition to the mixed liquid in which the agents are mixed, the two agents before mixing may be collectively referred to as hair coloring agents.

  The hair dye base solution is a solution containing a polyphenol constituent compound and an oxidation aid.

  A polyphenol constituent compound is a compound that constitutes polyphenols that play a role of pigments on the surface of hair by oxidative polymerization with each other. The polyphenol-constituting compound may also be a compound generally classified as a polyphenol.

  Examples of such polyphenol-constituting compounds include quercetin, resveratrol, oxyresveratrol, chlorogenic acid, catechin, epigallocatechin, tetrahydropiperine, rosmarinic acid, epicatechin gallate, epigallocatechin gallate, bradylin, ellagic acid Xymenic acid, ursolic acid, lupeol, proanthocyanidins, L-dopa, β-glucogallin, hematein, anthocyanins, and the like can be used. Any one of these polyphenol-constituting compounds may be used, or two or more may be used in combination.

  In addition, the polyphenol constituent compound is contained in the hair dye base solution in an amount of 0.01 to 3.0% by weight, more preferably 0.2 ± 0.1% by weight. When the content is less than 0.01% by weight, the formation rate of polyphenol formed by polymerization is slow, which is not preferable. Even if the concentration exceeds 3.0% by weight, the effect of improving the formation rate of polyphenol cannot be expected, which is not economical. By setting the concentration of the polyphenol constituent compound in the hair dye base solution to 0.01 wt% or more and 3.0 wt% or less, preferably 0.2 ± 0.1 wt%, polyphenols can be efficiently formed.

  By the way, a general polyphenol-based hair coloring agent causes a polymerization reaction by causing an oxidase to act on such a polyphenol-constituting compound, and synthesizes polyphenols exhibiting a predetermined color to color hair. There are many cases. Therefore, as described above, there is a problem that the color development speed is relatively slow.

  Therefore, in the hair coloring agent with a spray container according to the present embodiment, an oxidation aid is added to the hair dye base solution as one of the characteristic configurations.

  This oxidizing aid is a compound that is oxidized by an oxidase contained in an oxidase solution described later, and is particularly a compound that is oxidized by an oxidase in preference to a polyphenol constituent compound.

  In other words, comparing the compound that constitutes the oxidation auxiliary agent and the polyphenol component compound from the viewpoint of the reaction rate in the oxidase, the number of molecules oxidized per unit time by a predetermined amount of oxidase is greater than that of the polyphenol component compound. I try to use more drugs.

  In order to achieve such a relationship between the compound constituting the oxidation aid and the polyphenol constituting compound, for example, the compound constituting the oxidation aid can be a compound having a lower molecular weight than the polyphenol constituting compound.

  By setting it as such a structure, an oxidase will preferentially oxidize an oxidation adjuvant over a polyphenol compound.

  Moreover, the compound which comprises an oxidation adjuvant is made into the compound which is hard to oxidize compared with a polyphenol structural compound. In other words, the compound constituting the oxidation aid is a compound that can oxidize the polyphenol-constituting compound when it is in the oxidized form.

  Therefore, an oxidation aid that has been oxidized efficiently and in large quantities by oxidase functions as an oxidant for the polyphenol constituent compound to undergo oxidative polymerization, compared to when the polyphenol constituent compound is oxidatively polymerized only by oxidase. And can quickly produce polyphenols.

  That is, in the hair coloring agent with a spray container according to the present embodiment, since the oxidation auxiliary agent is added to the hair dye base solution, the color development speed can be improved.

  As a compound constituting such an oxidation aid, a compound generally called simple polyphenol can be used. For example, divalent phenol catechol, trivalent phenol pyrogallol, gallic acid, or the like can be used. .

  Further, the concentration of the oxidation aid in the hair dye base solution is preferably 0.001 to 0.01% by weight, preferably 0.001 to 0.005% by weight, and particularly preferably 0.002 ± 0.001% by weight. When the content is less than 0.001% by weight, the formation rate of polyphenol formed by polymerization, that is, the color development rate becomes slow, which is not preferable. Even if the concentration exceeds 0.01% by weight, the effect of improving the formation rate of polyphenol cannot be expected, which is not economical. By setting the concentration of the oxidation aid in the hair dye base solution to 0.001 wt% or more and 0.01 wt% or less, preferably 0.002 ± 0.001 wt%, polyphenols can be efficiently formed.

  On the other hand, the oxidase solution mixed with the hair dye base solution contains oxidase in the solution.

  As the oxidase contained in the oxidase solution, laccase, which is a copper enzyme that catalyzes the reaction of converting benzenediol into benzoquinone, is preferably used. In addition, tyrosinase and bilirubin oxidase can be used.

  These oxidases oxidize the hydroxyl group of the aromatic ring when mixed with a polyphenol-constituting compound having an aromatic ring substituted with a hydroxyl group or an oxidation aid. In particular, in the hair coloring agent in the present embodiment, the oxidation aid is oxidized in preference to the polyphenol constituent compound.

  Then, the oxidation auxiliary agent converted into an oxidized form by the oxidase secondarily oxidizes the polyphenol constituent compound, and the polymerization between the polyphenol constituent compounds or the polymerization between the already formed polyphenols and the polyphenol constituent compound is promoted. Will be.

  The concentration of the oxidase in the oxidase solution is 0.01 to 2.0% by weight, preferably 0.5 to 1.0% by weight. When the concentration of the oxidase is less than 0.01% by weight, the formation rate of polyphenols, that is, the color development rate becomes slow. Further, even if the concentration of the oxidase exceeds 2.0% by weight, it is not economical because a significant improvement in the color development rate cannot be expected. By containing 0.01 to 2.0% by weight, preferably 0.5 to 1.0% by weight of the oxidase in the oxidase solution, efficient color development can be performed.

  Thus, in the hair coloring agent containing a spray container according to this embodiment, the hair dye base solution and the oxidase solution prepared as described above are accommodated in the spray container as a hair coloring agent.

  In addition, the hair coloring agent containing the spray container according to the present embodiment is characteristically stored separately in the two storage sections partitioned in the spray container, the hair dye base solution and the oxidase solution. . That is, a two-component spray container that is isolated so that both the hair dye base solution and the oxidase solution are not mixed before spraying is used, and the hair dye base solution and the oxidase solution are immediately discharged from the nozzle. Try to mix.

  By adopting such a configuration, it is possible to start the reaction at the time of use while suppressing the reaction between the hair dye base solution and the oxidase solution contained in the spray container. The present hair dye can be uniformly attached. In addition, the amount of the hair coloring agent adhering to the scalp can be reduced as much as possible. Furthermore, it is easy to partially dye the hair.

  Further, it is desirable to use a container that can seal at least a section for storing the hair dye base solution as the spray container. The polyphenol and the oxidation auxiliary agent contained in the hair dye base solution are liable to cause air oxidation, and the use of a sealable container can prevent the hair dye base solution from being modified as much as possible.

  In addition, in this embodiment, although the container which accommodates a hair coloring agent is used as the spray container, it is not necessarily limited to this. For example, the container for storing the hair coloring agent may be a dripping type as well as a spraying type (aerosol type).

  The hair coloring agent in the present embodiment is a dye that dyes a polyphenol component compound and an oxidase by oxidation reaction in the cuticle of hair, and this oxidation reaction is mixed when the solution dries. No longer reacts. When the container is a spray type, the mixed solution is in a spray form as compared with the dropping type, and thus the time until drying is short. Therefore, in the case of the dropping type, there is an advantage that the time until drying is lengthened and the reaction time can be secured.

  However, when it is inconvenient when the hair remains wet, for example, when it is desired to dye hair immediately before going out, it is desirable that the time until drying is short.

  On the other hand, in the hair coloring agent with a spray container according to the present embodiment, the hair dye base solution contains an oxidation auxiliary agent, and can rapidly develop color as described above. Therefore, even if the container is a spray type, a desired hair color can be obtained before the hair coloring agent attached to the hair surface is dried.

  That is, it can be said that the hair coloring agent in a spray container according to the present embodiment is a hair coloring agent in a container that can achieve both rapid drying of hair and sufficient color development in a short time.

  Below, the hair coloring agent containing a spray container concerning this embodiment is demonstrated more concretely, referring drawings, a preparation example, a test result, etc.

  Drawing 1 is an explanatory view showing the state where hair coloring agent A with a spraying container concerning this embodiment is used. As shown in FIG. 1, the hair coloring agent A in the spray container is used by spraying the hair coloring agent 10 contained in the spray container 11 toward the hair H by the user P.

  FIG. 2 is an explanatory view showing the appearance of the hair coloring agent A in the spray container according to the present embodiment. A container manufactured by Sanpo Kasei Co., Ltd. is used as the spray container of this embodiment.

  As shown in FIG. 2, a hair coloring agent A containing a spray container includes a hair coloring agent 10 for dyeing hair, and a spray container 11 for containing the hair coloring agent 10 and spraying it in use. It consists of.

  The hair coloring agent 10 is composed of a hair dye base solution 10a containing a polyphenol constituent compound constituting polyphenols by oxidative polymerization with each other and the above-mentioned oxidizing aid, and an oxidase enzyme solution 10b containing an oxidase. Composed. The composition of the hair dye base solution 10a and the oxidase solution 10b will be described in detail later, and here, first, the configuration of the spray container 11 will be mainly described.

  The spray container 11 sucks and sprays the container main body 12 for storing the hair coloring agent 10 and the hair coloring agent 10 (the hair dye base solution 10a and the oxidase solution 10b) stored in the container main body 12. It is comprised with the pump part 13 for doing.

  The container body 12 is provided with a partition wall 12b that bisects the internal space in a peripheral wall 12a that forms the appearance of the container.

  That is, the inside of the container main body 12 is partitioned by the partition wall 12b, and a hair dye base solution storage space 14a as a first storage portion and an oxidase solution storage space 14b as a second storage portion are formed. .

  The hair dye base solution 10a and the oxidase enzyme solution 10b are separately stored in the hair dye base solution storage space 14a and the oxidase solution storage space 14b, respectively, so that they do not mix with each other in the container body 12. Yes.

  The pump part 13 is a part for sucking up and spraying the hair coloring agent 10 accommodated in the container main body part 12, and includes a pump base part 15 and a pressing nozzle 16.

  The pump base 15 is a member formed separately from the container main body 12 and is configured to be fitted in a sealed state in an opening (not shown) formed in the upper part of the container main body 12.

  That is, the pump base 15 has a degree that the hair coloring agent 10 does not flow out and the air oxidation of the hair dye base solution 10a does not proceed even when the hair coloring agent A in the spray container falls, for example. It is configured to ensure a tightness.

  Two suction tubes 17 are disposed below the pump base 15. These suction tubes 17 are provided at the back surface positions of the pump base 15 corresponding to the hair dye base solution storage space 14a and the oxidase solution storage space 14b, respectively, when the pump unit 13 is fitted to the container body 12. Yes.

  Further, inside the pump base portion 15, a pump mechanism (not shown) that is activated by the operation of the pressing nozzle 16 and a hair coloring agent 10 sucked up through the suction tube 17 by the operation of the pump mechanism are guided to the pump mechanism. An upper flow path and a discharge flow path for guiding the hair coloring agent 10 discharged by the operation of the pump mechanism to the spray ports 18a and 18b described later are provided, and are stored in the hair dye base liquid storage space 14a. The hair dye base solution 10a and the oxidase enzyme solution 10b accommodated in the oxidase solution storage space 14b each flow through a suction tube 17 through a suction channel, a pump mechanism, and a discharge channel (not shown) through the spray port. It is comprised so that it may be guide | induced to 18a, 18b. The spray ports 18a and 18b are oriented at an angle such that the sprayed hair dye base solution 10a and the oxidase enzyme solution 10b intersect each other, and when the hair dye base solution 10a and the oxidase solution 10b are sprayed from the container. It is configured to mix.

  On the upper part of the pump base 15, a pressing nozzle 16 having spray ports 18 a and 18 b for discharging the hair coloring agent 10 in a mist form is disposed.

  The pressing nozzle 16 is connected to a pump mechanism disposed in the pump base 15 via an elastic body, and the pump mechanism is activated when the user P presses the pressing nozzle 16 against the elastic force. It is configured as follows.

  Thus, the spray container 11 of the hair coloring agent A containing the spray container according to the present embodiment separately accommodates the hair dye base solution 10a and the oxidase enzyme solution 10b in two compartments partitioned inside. However, it can be mixed and sprayed at the time of use.

  Next, the hair coloring agent 10 accommodated in the spray container 11 will be specifically described with reference to preparation examples and test results.

[1. Preparation of hair dye base solution)
First, the hair dye base solution which comprises a hair coloring agent was prepared. Here, two types of hair dye base solutions X1 and X2 having different concentrations using catechol as an oxidation aid and two types of hair dye base solutions having different concentrations using pyrogallol as an oxidation aid. A total of five samples of X3 and hair dye base solution X4 and a comparative base solution Y1 not containing an oxidizing aid were prepared. The specific composition is shown in Table 1. The pH values of the comparative base solution Y1 and the hair dye base solution X1 to the hair dye base solution X4 were all adjusted to 4.6.

  The hair dye base solutions X1 to X4 and the comparative base solution Y1 shown in Table 1 were prepared as follows.

  Add 0.2 g of hydroxypropyltrimonium chloride (DOC Japan Co., Ltd., DOCSTARCH CP) and 0.1 g of white jellyfish polysaccharide (Nihon Seika Co., Ltd., Tremoist-TP) to deionized water, up to 80 ° C. After warming, the mixture was sufficiently dissolved while stirring for 20 minutes, and then cooled to 40 ° C. (Liquid L1).

  Next, 5.0 g of ethoxydiglycol (manufactured by Gatefosse, TRANSCUTOL CG), 0.255 g of citric acid (anhydrous), and 0.245 g of trisodium citrate dihydrate were added to the L1 solution and dissolved while stirring. (L2 liquid).

  Next, cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol (manufactured by Nippon Seika Co., Ltd., Neosolue-Aqulio) and ethanol were stirred and dissolved in another container, and then added to the above-mentioned L2 liquid (L3 liquid).

  Next, 5.0 g of 1,3-butylene glycol (manufactured by Daicel Chemical), 0.045 g of L-tyrosine, 0.0045 g of L-cysteine, 2.0 g of quercetin (manufactured by Tokiwa Plant Chemical Research Co., Ltd.), and hair dye base solution X1 In the hair dyeing base solution X2, 0.2 g of catechol, in the hair dyeing base solution X3, 0.1 g, and in the hair dyeing base solution X4, 0.2 g of pyrogallol was stirred and mixed in a separate container and added to the L3 solution (L4 solution). ). In the preparation of the comparative base solution Y1, no catechol or pyrogallol was added.

  Next, 0.02 g of hydrolyzed keratin (manufactured by Seiwa Chemical Co., Ltd., Promois KR-30), 0.04 g of polyaminopropyl biguanide (manufactured by Nikko Chemicals Co., Ltd., Cosmocil CQ) and 0.1 g of L-ascorbic acid were added to the L4 solution. The solution was stirred and dissolved (Liquid L5).

  And this L5 liquid is adjusted to 100 g with deionized water, and the hair dyeing base solution X1 to hair dyeing base solution X4 as the hair dyeing base solution constituting the hair coloring agent and comparison used as a control in the test described later A base solution Y1 was obtained.

[2. Preparation of enzyme solvent
Next, the oxidase solution which comprises a hair coloring agent was prepared. Specific compositions are shown in Table 2. The pH value of the oxidase solution was adjusted to 4.6.

  The oxidase solution shown in Table 2 was prepared as follows.

  Hydroxypropyltrimonium chloride starch and white jellyfish polysaccharide were added to deionized water, heated to 80 ° C, stirred and dissolved for 20 minutes, and then cooled to 40 ° C (L6 solution).

  Next, 0.255 g of anhydrous citric acid (manufactured by Iwata Chemical Co., Ltd.) and 0.245 g of trisodium citrate dihydrate (manufactured by Iwai Chemical Co., Ltd.) are sufficiently dissolved in deionized water in a separate container, Was added to L6 solution (L7 solution).

  Next, 15.0 g of 1,3-butylene glycol (manufactured by Daicel Chemical Industries) and laccase (manufactured by Amano Enzyme, M120, laccase derived from white rot fungus (Trametes sp.) (EC 1.10.3.2, activity 108,000 U / g or more), 3.0 g Was sufficiently dissolved in deionized water in a separate container, and then added to the L7 solution (L8 solution).

  Next, 0.02 g of hydrolyzed keratin (manufactured by Seiwa Chemical Co., Ltd., Promois KR-30), 0.04 g of polyaminopropyl biguanide (manufactured by Nikko Chemicals Co., Ltd., Cosmocil CQ) and 0.1 g of L-ascorbic acid (manufactured by Maruzen Pharmaceutical Industry Co., Ltd.) The solution was added to the L8 solution and dissolved by stirring (L9 solution).

  And this L9 liquid was adjusted to 100g with deionized water, and the oxidase enzyme liquid which comprises a hair coloring agent was obtained.

[3. (Color development speed verification test)
Next, in order to examine the difference in the color development rate due to the presence of the oxidation aid in the hair dye base solution, the change with time at a wavelength of 450 nm was measured using a spectrophotometer.

  Specifically, 5 ml of a sample prepared by mixing an equal amount of any one of hair dye base solutions X1, X2 and comparative base solution Y1 and an oxidase solution was transferred to a quartz glass cell, and a spectrophotometer (V- 530 UV / VIS Spectrophotometer: JASCO). Moreover, the measurement was performed 3 times in total, 5 minutes later and 10 minutes later, with 0 minute immediately after mixing. The results are shown in Table 3.

  As can be seen from Table 3, the comparative base solution Y1 to which no oxidation assistant was added had an absorbance of 0.55489 after 10 minutes, whereas the hair dye base solution X1 to which catechol was added as an oxidation aid. And X2 both showed higher absorbance than the comparative base solution Y1.

  Further, the hair dye base solution X1 to which catechol was added at 0.1% had an absorbance of 0.65338, whereas the hair dye base solution X2 to which catechol was added at 0.2% had an absorbance of 0.75223. It was suggested that it is possible to change the hair dyeing speed by changing the concentration of.

[4. Hair dyeing test 1]
Next, the hair coloring agent A containing the spray container according to the present embodiment was used for white hair of human hair, and the difference in coloration due to the presence of the oxidation auxiliary agent was examined.

  Specifically, about 0.8g of a hair coloring agent in a mixed state is sprayed and applied to 1g of human white hair parts (product number BM-WA, manufactured by Beaulux Co., Ltd.). The hair sample washed with shampoo after being left at room temperature for 2 hours and dried with a dryer was subjected to measurement with a color difference meter. In addition, five types of hair samples, one using X1 to X4 as a hair dye base solution to be mixed with an oxidase solution and one using a comparative base solution Y1, were prepared.

  The five hair samples thus obtained were measured with a color difference meter (manufactured by NIPPONN DENSHOKU, NR-300) using the color value before dyeing as a reference color. The results are shown in Table 4.

  As can be seen from Table 4, according to the hair coloring agent A in the spray container provided with the hair coloring agent using the hair dye base solutions X1 to X4, when the comparison base solution Y1 containing no oxidation auxiliary is used It was shown that good hair dyeing results can be obtained as compared with.

[5. Hair dyeing test 2]
Next, regarding the assumed dyeing time (after 5 minutes and 10 minutes) from when the hair coloring agent A is actually applied to the hair to drying, the hair coloring agent A in the spray container according to this embodiment is used. Was used for human white hair, and the difference in coloration due to the presence of an oxidizing aid was examined.

  Specifically, about 0.8g of a hair coloring agent in a mixed state is sprayed and applied to 1g of human white hair parts (product number BM-WA, manufactured by Beaulux Co., Ltd.). The hair samples washed with shampoo after standing at room temperature for 5 minutes or 10 minutes and dried with a dryer were subjected to measurement with a color difference meter. In addition, five types of hair samples, one using X1 to X4 as a hair dye base solution to be mixed with an oxidase solution and one using a comparative base solution Y1, were prepared.

  The five hair samples thus obtained were measured with a color difference meter (manufactured by NIPPONN DENSHOKU, NR-300) using the color value before dyeing as a reference color. The results for the dyeing time of 5 minutes are shown in Table 5, and the results for the dyeing time of 10 minutes are shown in Table 6.

  As can be seen from Tables 5 and 6, according to the hair coloring agent A in the spray container provided with the hair coloring agent using the hair dye base solutions X1 to X4, it is assumed to be applied to the hair and dried. It was shown that the hair coloring result can be obtained that the color of the hair can be changed in the time (5 minutes, 10 minutes) applied.

で示される酸化補助剤とを混合した染毛基液に酸化酵素液を混合して、ノズルから噴霧可能に構成したため、ノズルから噴霧可能に構成したため、使用者による手のひら上での混合作業の必要がなく、しかも、従来のポリフェノール系ヘアカラーリング剤に比して速やかに目的色に染毛することのできる噴霧容器入りヘアカラーリング剤を提供することができる。 As described above, according to the hair coloring agent A contained in the spray container according to the present embodiment, the polyphenol constituting compound constituting the polyphenols by oxidative polymerization with each other, and the general formula [I]:

Since the oxidase enzyme solution is mixed with the hair dye base solution mixed with the oxidation auxiliary agent shown in Fig. 1 and is configured to be sprayable from the nozzle, it is configured to be sprayable from the nozzle, so the user needs to perform mixing work on the palm. In addition, it is possible to provide a hair coloring agent in a spray container that can be dyed to the target color more quickly than conventional polyphenol hair coloring agents.

DESCRIPTION OF SYMBOLS 10 Hair coloring agent 10a Hair dye base solution 10b Oxidase enzyme solution 11 Spray container 12b Bulkhead 13 Pump part 14a Hair dye base solution storage space 14b Oxidase solution storage space 18a, 18b Spray port A Hair coloring agent with spray container

Claims (6)

Polyphenol constituent compounds that constitute polyphenols by oxidative polymerization with each other, and the general formula [I]:

A hair coloring agent in a spray container, characterized in that it is configured to be sprayable from a nozzle by mixing an oxidase enzyme solution with a hair dye base solution mixed with an oxidation auxiliary agent represented by
The hair dye base solution contains 0.01 to 3% by weight of the polyphenol constituent compound and 0.001 to 0.01% by weight of the oxidative aid, and the oxidase solution contains 0.01 to 2% by weight of oxidase. ,
The hair dye base solution and the oxidase solution are separately stored in two storage sections partitioned in the spray container, and the spray ports of the nozzles are arranged at angles at which the sprayed liquids intersect each other. A hair coloring agent in a spray container, wherein the hair dye base solution and the oxidase solution are mixed immediately after being blown out. Polyphenol constituent compounds that constitute polyphenols by oxidative polymerization with each other, and the general formula [I]:

A hair coloring agent in a spray container, characterized in that it is configured to be sprayable from a nozzle by mixing an oxidase enzyme solution with a hair dye base solution mixed with an oxidation auxiliary agent represented by
The Somekemotoeki includes: the polyphenol structure compound of 0.01 to 3 wt%, and a said oxidizing aids 0.1-0.2 wt%, the oxidation enzyme solution, together containing 0.01 to 3 wt% of the oxidase ,
The hair dye base solution and the oxidase solution are separately stored in two storage sections partitioned in the spray container, and the spray ports of the nozzles are arranged at angles at which the sprayed liquids intersect each other. A hair coloring agent in a spray container, wherein the hair dye base solution and the oxidase solution are mixed immediately after being blown out. 3. The oxidation auxiliary agent according to claim 1 or 2 , wherein the oxidative auxiliary agent has a higher substrate binding property to an oxidase contained in the oxidase solution than the polyphenol constituent compound and is not easily oxidized. The hair coloring agent in a spray container as described. The hair coloring agent in a spray container according to any one of claims 1 to 3 , wherein the oxidation auxiliary agent is catechol, pyrogallol, gallic acid, or a mixture thereof. The oxidase contained in oxidase solution, laccase, tyrosinase, one of claims 1-4, characterized in that any one of polyphenol oxidase, or two or more polyphenol oxidase mixed enzyme selected from bilirubin oxidase A hair coloring agent in a spray container according to claim 1. The hair coloring agent in a spray container according to any one of claims 1 to 5 , wherein the polyphenol constituent compound is quercetin.

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