JP6511896B2 - Coating composition for lid for PTP packaging, and PTP package using the same - Google Patents

Description

  TECHNICAL FIELD The present invention relates to a coating composition of a PTP (Press Through Pack) package used for packaging pharmaceuticals and the like.

  A PTP package, which is widely used for packaging pharmaceuticals and the like, comprises two parts, a base material for storing contents and a lid material for sealing the base material containing contents. The bottom material is constituted by a processed and formed body of a plastic sheet in which a pocket is formed. The lid is formed by providing a printing layer such as characters and designs on one side or both sides of a metal foil, particularly aluminum foil, and further providing a coating agent layer and a heat sealing agent layer on each side thereof. .

  As a plastic sheet for forming the bottom material, a vinyl chloride resin sheet, a polypropylene sheet or the like is used because it is excellent in processability. On the other hand, mainly metal foils, particularly aluminum foils, are usually used as the base material of the lid because of the method of using the PTP package in which the lid is ruptured and the contents are taken out.

  In the packing operation, the contents are filled and the heat sealing operation is carried out by storing the contents in a processed and formed product of a vinyl chloride resin sheet or a polypropylene sheet provided with a pocket serving as the above-mentioned bottom material, The lid of the foil is laminated so that the heat sealing agent layer comes in contact, and heat and pressure is applied to the non-pocket portion of the plastic container by heating and pressing with a heat sealing roll from the surface provided with the coating agent layer of the lid. It is accomplished by

  The surface of the heat sealing roll is usually embossed in a grid pattern, and the heating and pressing conditions differ depending on the type of laminated material, but the roll temperature and the roll pressure are 120 to 280 ° C. and 0. 0, respectively. It is often set between 1 and 0.6 MPa.

  As the coating agent for the lid, a thermosetting resin such as an epoxy-amino resin or a nitrifying cotton-amino resin is usually used in the resin composition. The heat sealing agent is usually made of a thermoplastic resin, and depending on the material of the processed and formed body (plastic container), vinyl chloride-vinyl acetate copolymer, ethylene-vinyl acetate copolymer, chlorinated polypropylene, acid modified, respectively. A resin composition containing a resin such as polypropylene as a main component is used (Patent Document 1).

Japanese Patent Publication No. 5-0330

  When a thermosetting resin such as an epoxy-amino resin or a nitrifying cotton-amino resin is used as the resin component of the coating agent composition, the heat resistance of the aluminum foil itself at the time of heat sealing and the printing layer such as characters and design is good. However, formaldehyde is easily released during the coating operation of the coating agent, the packaging operation, and the storage environment in the PTP package after heat sealing.

  Depending on the type of medicines stored, etc., it has an impact on health for workers during coating work and packaging work, and under storage environment in the PTP package state after heat sealing. There is a disadvantage that the medicinal quality itself decreases.

  However, when a thermosetting resin such as an epoxy-amino resin or a nitrifying cotton-amino resin is not used as the resin component of the coating agent composition, heat resistance sufficient to withstand the heating temperature at the time of heat sealing can not be obtained. Various problems occur such as discoloration and detachment of aluminum foil pinholes, thermal expansion glazes, coating agent layers and printing layers. There is a demand for technological development on a coating agent composition for a PTP package which does not easily release formaldehyde and which has heat resistance enough to withstand heating at the time of heat sealing.

  An object of the present invention is to provide a coating agent composition for a PTP package which does not release formaldehyde and has sufficient heat resistance.

  The inventors of the present invention have conducted intensive studies on the basis of these problems, and as a result, they contain a hydroxyl group-containing acrylic resin (A), a hydroxyl group-containing silicone-modified acrylic resin (B) and a polyisocyanate compound (C) blocked. It has been found that the coating agent composition is excellent for use in PTP packaging.

That is, the present invention is a coating agent composition for a lid for PTP packaging, which has a laminated structure in the order of a coating agent layer, an aluminum foil and a heat seal layer,
The coating agent composition is a hydroxyl group-containing acrylic resin (A) (with the exception of the following resin (B)), a hydroxyl group-containing silicon-modified acrylic resin (B), and a blocked polyisocyanate compound The present invention relates to a coating agent composition for a lid for PTP packaging, which comprises (C).

  Further, according to the present invention, a hydroxyl group-containing silicone-modified acrylic resin (B) comprises a monomer (a) having an α, β-unsaturated double bond group and a polyorganosiloxane chain; Monomer (b) having a heavy bond group and a hydroxyl group, and monomer (c) having an α, β-unsaturated double bond group (however, monomers (a) and (b)) The coating agent composition according to the present invention relates to the above-mentioned coating agent composition in which the monomer (a) is 1.5 to 5% by weight based on the total of the resin (A) and the resin (B).

  The present inventors relate to the above-mentioned coating agent composition characterized in that the hydroxyl value of the hydroxyl group-containing acrylic resin (A) is 10 to 60 mg KOH / g.

  The present inventors relate to the above-mentioned coating agent composition characterized in that the dissociation temperature of the blocking agent of the blocked polyisocyanate compound (C) is 90 ° C. or less.

  The present inventors relate to a lid for PTP packaging, which is obtained by coating the above-mentioned coating agent composition on aluminum foil and thermally curing it.

  The present inventors further relate to the above-mentioned lid member having a heat seal layer on the aluminum foil surface opposite to the coating agent layer.

  The present inventors relate to a PTP package formed by heat-sealing a transparent plastic bottom material with the lid material.

  In the application of the coating agent composition of the present invention to a PTP package, formaldehyde is not released during the coating operation of the coating agent, during the packaging operation, or under the storage environment in the PTP package after heat sealing. Therefore, it does not cause harmful effects on health of formaldehyde to workers and users. Also, the contents to be packaged are not affected by formaldehyde. Furthermore, it withstands the heating temperature at the time of heat sealing, and there is no occurrence of various problems such as discoloration and detachment of pinholes of the base material such as aluminum foil, thermal expansion scale, coating agent layer and printing layer.

  Hereinafter, the coating agent composition of the present invention and the application of the coating agent composition to a PTP package will be described. First, the coating agent composition will be described. The coating agent composition is characterized by containing a hydroxyl group-containing acrylic resin (A), a hydroxyl group-containing silicone-modified acrylic resin (B), and a blocked polyisocyanate compound (C). However, the hydroxyl group-containing silicon-modified acrylic resin (B) is not included in the hydroxyl group-containing acrylic resin (A).

  The hydroxyl group-containing silicone-modified acrylic resin (B) constituting the present invention comprises a monomer (a) having an α, β-unsaturated double bond group and a polyorganosiloxane chain, and an α, β-unsaturated double resin. A monomer (b) having a bonding group and a hydroxyl group, and a monomer (c) having an α, β-unsaturated double bond group (provided that the monomers (a) and (b) are excluded) ) And react.

  The hydroxyl group-containing acrylic resin (A) is a monomer (b) having an α, β-unsaturated double bond group and a hydroxyl group, and a monomer (c) having an α, β-unsaturated double bond group (Except in the case of the monomers (a) and (b)).

  The monomer (a) having an α, β-unsaturated double bond and a polyorganosiloxane chain is represented by the general formula a.

_{^{R 1: CH 2 = CH-}} COO- (CH 2) m -, CH 2 = C (CH 3) -COO- (CH 2) m -CH 2 = CH- (CH 2) m -, or CH ₂ = C (CH ₃ )-(CH ₂ ) _m- (m is an integer of 0 to 10)
R ^{2 is selected from} hydrogen, a methyl group, or the same functional group as R ¹ , R ³ , R ⁴ , R ⁵ , R ⁶ , R ⁷ , R ⁸ : an alkyl group, a phenyl group, a hydroxyl group or a carboxyl group.

Specifically, for example, one-terminal vinyl group-containing polyorganosiloxane compound such as TSL 9705 manufactured by Toshiba Silicone Co., Ltd., one end such as Silaprene FM-0711, FM-0721, FM-0725 manufactured by Chisso Co. The (meth) acryloxy group containing polyorganosiloxane compound etc. are mentioned. The monomer (a) having an α, β-unsaturated double bond group and a polyorganosiloxane chain is essential for imparting heat resistance sufficient to withstand heating at the time of heat sealing, and the required performance Accordingly, one or two or more of them can be mixed and used, and a copolymerization ratio of 1 to 80% by weight based on the resin (B) can be used, but the solvent containing no halogen atom can be used. In order to obtain sufficient solubility and the like, it is desirable to set the copolymerization ratio to 60% by weight or less.

  The monomer (b) having an α, β-unsaturated double bond group and a hydroxyl group is used for crosslinking after coating. Examples of the monomer (b) having an α, β-unsaturated double bond group and a hydroxyl group include 2-hydroxyethyl (meth) acrylate, 1-hydroxypropyl (meth) acrylate and 2-hydroxypropyl (meth) Acrylate, 4-hydroxybutyl (meth) acrylate, polyethylene glycol mono (meth) acrylate, polypropylene glycol mono (meth) acrylate, polytetramethylene glycol mono (meth) acrylate, hydroxystyrene and the like.

  The monomer (b) can be used alone or in combination of two or more of them depending on the required performance. Further, those used in the hydroxyl group-containing acrylic resin (A) and those used in the hydroxyl group-containing silicon-modified acrylic resin (B) are not necessarily the same.

  The monomer (c) having an α, β-unsaturated double bond group other than the monomer (a) or (b) used in the present invention has improved hardness, toughness, scratch resistance, gloss, etc. It is used for giving various coating film properties. As this monomer (i) (meth) acrylic acid derivative (however, except for a monomer having a hydroxyl group and a polyorganosiloxane chain), (ii) an aromatic vinyl monomer, (iii) an olefin hydrocarbon alone The monomer, (iv) vinyl ester monomer, (v) vinyl halide monomer, (vi) vinyl ether monomer and the like can be mentioned.

(i) Examples of (meth) acrylic acid derivatives include (meth) acrylonitrile, (meth) acrylate, methyl (meth) acrylate, butyl (meth) acrylate, ethylhexyl (meth) acrylate, stearyl (meth) acrylate, benzyl Examples include (meth) acrylates and the like.
(ii) Examples of the aromatic vinyl monomer include styrene, methylstyrene, ethylstyrene, chlorostyrene and the like.
(iii) Examples of the olefin hydrocarbon monomer include ethylene, propylene, butadiene, isobutylene, isoprene, 1,4-pentadiene and the like.
(iv) Examples of vinyl ester monomers include vinyl acetate and the like.
Examples of (v) vinyl halide monomers include vinyl chloride, vinylidene chloride, monofluoroethylene, difluoroethylene, trifluoroethylene and the like.
(vi) Examples of vinyl ether monomers include vinyl methyl ether and the like.
Two or more of these may be used. The monomer (c) is used in an amount of 0 to 90% by weight in the hydroxyl group-containing acrylic resin (A) and the hydroxyl group-containing silicon-modified acrylic resin (B). If it is more than 90% by weight, sufficient adhesion to the substrate can not be obtained. In addition, the compatibility between the hydroxyl group-containing acrylic resin (A) and the hydroxyl group-containing silicon-modified acrylic resin (B) decreases, and a uniform and good coating film can not be obtained.

  The hydroxyl group-containing acrylic resin (A) and the hydroxyl group-containing silicon-modified acrylic resin (B) can be obtained by a known method, for example, solution polymerization. As a solvent to be used, alcohols such as methanol, ethanol, propanol, butanol, ethylene glycol methyl ether, diethylene glycol methyl ether, acetone, methyl ethyl ketone, ketones such as methyl isobutyl ketone and cyclohexanone, tetrahydrofuran, dioxane, ethylene glycol dimethyl ether, diethylene glycol dimethyl ether It is possible to use ethers such as ethers, hydrocarbons such as hexane, heptane and octane, aromatics such as benzene, toluene, xylene and cumene, and esters such as ethyl acetate and butyl acetate. The solvent may be a mixture of two or more. The feed concentration of the monomer at the time of synthesis is preferably 0 to 80% by weight.

  As a polymerization initiator, common peroxides or azo compounds such as benzoyl peroxide, azoisobutylvalenonitrile, azobisisobutyronitrile, di-t-butyl peroxide, t-butyl perbenzoate, t-butyl Peroctoate, cumene hydroxyperoxide and the like are used, and the polymerization temperature is 50 to 140 ° C, preferably 70 to 140 ° C. The preferable average weight molecular weight of the polymer obtained is 2,000 to 100,000 for both the hydroxyl group-containing acrylic resin (A) and the hydroxyl group-containing silicon-modified acrylic resin (B).

  Since the monomer (a) has a polyorganosiloxane chain, the resin (B) obtained by copolymerizing the monomer (a) or the like tends to segregate on the surface of the coating film and contributes to heat resistance. . Also, conversely, if the polysiloxane chain is present in the coating film more than necessary, a part thereof is also present on the aluminum foil side, and the adhesion between the aluminum foil or the printing ink layer and the coating film is lowered. It becomes easy to do. In order to sufficiently obtain the heat resistance and adhesion of the coating film, the monomer (a) is a solid content relative to the total of the hydroxyl group-containing acrylic resin (A) and the hydroxyl group-containing silicon-modified acrylic resin (B) It is particularly desirable that the ratio be 1.5 to 5% by weight. If the amount is less than 1.5% by weight, the heat resistance may be insufficient. If the amount is more than 5% by weight, the adhesion may not be sufficient.

  The hydroxyl value of the hydroxyl group-containing acrylic resin (A) is preferably 10 to 60 mg KOH / g. If it is less than 10 mg KOH / g, sufficient crosslinking reaction may not proceed, and if it is more than 60 mg KOH / g, sufficient coating agent stability may not be ensured.

  The hydroxyl value was determined by the following method. Add 25 cc of an acetylating agent mixed with acetic anhydride and pyridine at a volume ratio (acetic anhydride / pyridine) of 1/9 to 40 g of sample, react at 100 ° C. for 1 hour, add 10 cc of n-butanol and add N / 2 It titrated with the alcohol solution of potassium hydroxide, and calculated | required the hydroxyl value.

  The blocked polyisocyanate compound (C) used in the present invention is one in which an isocyanate group is reacted with an active hydrogen group-containing compound (blocking agent) to render it inactive at room temperature, and when this is heated, the blocking agent It has the property of being dissociated to regenerate an isocyanate group. For this reason, it becomes possible to mix | blend beforehand with the main ingredient which has an active hydrogen group by blocking the isocyanate group of a hardening | curing agent.

  As a blocking agent for blocking an isocyanate group, alcohols, phenols, lactams, oximes, acetoacetic acid alkyl esters, malonic acid alkyl esters, phthalimides, imidazoles, hydrogen chloride, hydrogen cyanide or sodium hydrogen sulfite Etc. are known. Among these, blocked isocyanate compounds in which an isocyanate group is blocked with substituted phenols, oximes, acetoacetic acid alkyl esters, malonic acid alkyl esters, phthalimides, imidazoles, hydrogen chloride, hydrogen cyanide or sodium hydrogen sulfite, It dissociates at relatively low temperature to regenerate isocyanate groups.

  The blocked polyisocyanate compound (C) of the present invention is preferably an aliphatic isocyanate type, more preferably an HDI type. The use of aliphatic isocyanates is characterized in that the coating composition is less likely to yellow as compared to the use of aromatic isocyanates. The blocking agent is preferably an active methylene type such as acetoacetic acid alkyl esters or malonic acid alkyl esters which dissociates at a relatively low temperature so that a sufficient curing reaction proceeds in the drying step after coating agent application, and the blocking agent The dissociation temperature of is preferably 90 ° C. or less.

  The dissociation temperature of the blocked polyisocyanate compound (C) was determined by measuring the temperature at which the gel fraction of the heat-cured coating film is 90% by weight or more. The gel fraction is prepared by blending a hydroxyl group-containing acrylic resin having a hydroxyl value of 100 mg KOH / g and a blocked polyisocyanate compound (C) so that the isocyanate equivalent becomes 1.0, and coating the film for 30 minutes in an electric oven It heat-hardened and calculated | required from the insoluble content after immersing the obtained coating film in 20 degreeC acetone for 24 hours.

  The OH groups of the hydroxyl group-containing acrylic resin (A) and the hydroxyl group-containing silicon-modified acrylic resin (B) undergo a crosslinking reaction with NCO groups after dissociation of the blocked polyisocyanate compound (C). The addition amount of the blocked polyisocyanate compound (C) is preferably 0.6 to 1.4 in equivalent.

  In the present invention, other resins are used in combination with the hydroxyl group-containing acrylic resin (A), the hydroxyl group-containing silicon-modified acrylic resin (B) and the blocked polyisocyanate compound (C) for the purpose of improving the coating film performance. be able to. Other resins include nitrified cotton, vinyl chloride / vinyl acetate copolymer, polyester resin, polyamide resin, polyvinyl butyral and the like.

  In addition, if necessary, antiblocking agents such as fine powder silicon and zeolite, slip agents such as dimethylpolysiloxane and wax, pigments, antioxidants, ultraviolet absorbers, matting materials such as silica powder, etc., formaldehyde is not included. Additives can be included.

  The coating agent composition of the present invention is a PTP package comprising a base of a molded transparent plastic sheet and a lid of an aluminum foil, and an aluminum foil which is in contact with the surface of the transparent plastic sheet that contacts the base of the transparent plastic sheet via a heat seal layer. Is coated on the opposite side to become a coating agent for PTP packaging.

  A well-known aluminum base material can be used for the aluminum foil used as a base material, and it is not particularly limited, but an aluminum base material having a thickness of 5 μm to 50 μm and an aluminum purity of 98.0 to 99.9% by weight It can be used preferably. According to JISH4160, aluminum substrates such as 1000 series (1N30, 1070, etc.), 3000 series, 8000 series (8021, 8079, etc.) can be used, and the temper (sort by quality) is also a hard material (H material (JISH0001)) Both semi-hard and soft materials (O material (JISH0001)) can be used. In particular, when used for PTP packaging, hard materials are preferred. The above-mentioned aluminum base is called a glossy surface on one side and a glossy surface on the other side (also referred to simply as a poppy surface), and the gloss on both sides is different. The coating agent layer may be provided on either side of the surface. Moreover, you may provide printing layers, such as a character and a design, between an aluminum base material and a coating agent layer.

Coating agent layer is preferably a unit area per ^{0.5g / m 2 ~3.0g / m 2} , more preferably from 1.0 to 2.0 g / m ^2. The coating agent layer is formed by printing and coating. The printing and coating methods include known methods such as printing by gravure printing, offset printing, flexographic printing, etc., coating by a gravure roll coater, curtain flow coater or the like, and coating.

  The coating agent coating for PTP packaging in which the coating agent layer is formed is coated with a heat seal agent on the opposite surface to form a heat seal layer, and becomes a lid of aluminum foil, and heat is applied from the surface provided with the coating agent layer. The PTP package heat-sealed by heat-sealing with the bottom material of the transparent plastic sheet by heating and pressing with a sealing roll.

Hereinafter, the present invention will be described in more detail by way of Examples and Comparative Examples, but the present invention is not limited thereto. In the present invention, “parts” and “%” represent “parts by weight” and “% by weight”, respectively, unless otherwise specified.

Synthesis Example 1 Resin (A1)
Charge 9.5 g of 2-hydroxyethyl methacrylate, 60 g of methyl methacrylate, 30.5 g of butyl methacrylate and 200 g of methyl ethyl ketone (MEK) into a four-necked flask equipped with a condenser, a stirrer and a thermometer while stirring under a nitrogen stream. The temperature was raised to 80 ° C., 1.6 g of azobisisobutyronitrile was added and polymerization was carried out for 2 hours, and 0.4 g of azobisisobutyronitrile was further added and polymerization was conducted for 2 hours. Then, MEK was added so that solid content might be 30%, and the hydroxyl value containing acrylic resin (A1) solution of hydroxyl value 40 mgKOH / g was obtained.

Synthesis Examples 2 to 5 Resins (A2) to (A5)
The synthesis example 2-the synthesis example 5 were synthesize | combined by the same method as the synthesis example 1 except having changed it into the mixing | blending of Table 1, and obtained the hydroxyl-containing acrylic resin (A2)-(A5) solution. The solid content and the hydroxyl value of the obtained resins (A2) to (A5) are shown in Table 1.

(Synthesis example 6 resin (B))
45 g of one-terminal methacryloxy group-containing polysiloxane compound ("Silaplain FM-0721" manufactured by Chisso Corporation), 10 g of 2-hydroxyethyl methacrylate, 45 g of methyl methacrylate, 200 g of methyl ethyl ketone (MEK) as a cooling pipe, a stirrer, a thermometer Charge into a equipped four-necked flask, raise the temperature to 80 ° C while stirring under a nitrogen stream, add 1.6 g of azobisisobutyronitrile, perform polymerization reaction for 2 hours, and then add azobisisobutyronitrile 0 .4g was added and polymerization was performed for 2 hours. Thereafter, MEK was added so that the solid content was 30%, to obtain a hydroxyl group-containing silicon-modified acrylic resin (B) solution having a hydroxyl value of 42 mg KOH / g.
In addition, the symbol of the monomer used for the synthesis is as follows.
2HEMA: 2-hydroxyethyl methacrylate MMA: methyl methacrylate BMA: butyl methacrylate FM-0721: syraplane FM-0721

Example 1
Each resin solution is mixed so as to be 20 g of hydroxyl group-containing acrylic resin (A1) and 1 g of hydroxyl group-containing silicon-modified acrylic resin (B) in terms of solid content, and polyisocyanate compound (C1) (blocked as Asahi Kasei) We added "Duranate MFK-60B", manufactured by Chemicals Co., Ltd., blocking agent dissociation temperature: 90 ° C) so that the isocyanate equivalent becomes 1.0, and further added MEK to obtain a coating agent with a solid content of 20%. . These coating agents are coated with a bar coater on the shiny side of a 20 μm thick hard aluminum foil so that the dry coating amount will be about 1.5 g / m ² and heat cured in an electric oven at 180 ° C. for 10 seconds The coating agent coating was obtained.

(Examples 2 to 10, Comparative Examples 1 to 3)
The coating agent was produced by the same method as Example 1 except having changed into the compounding of Table 2 in Examples 2-10 and Comparative Examples 1-3, and the coating agent coating was obtained.
In the present specification, the coating agent and coating agent coating of Example 8 are reference examples.
In addition, the blocked polyisocyanate compound (C) used for the Example and the comparative example is described below.
(C1): manufactured by Asahi Kasei Chemicals Duranate MFK-60B, dissociation temperature 90 ° C.
(C2): manufactured by Asahi Kasei Chemicals Duranate SBN-70D, dissociation temperature 110 ° C.
(C3): manufactured by Asahi Kasei Chemicals Duranate E402-B80B, dissociation temperature 130 ° C.

  With respect to the coating agent and the coating agent coating material, the evaluation of the coating agent stability, adhesion, and heat resistance was performed. The evaluation results are shown in Table 2. The evaluation method and the evaluation criteria are as follows.

<Coating agent stability>
When finished, the viscosity of the coating agent and the viscosity after storage for 3 days in an electric oven at 40 ° C. were measured, and the coating agent stability was evaluated based on the degree of thickening. The viscosity is Zahn cup no. It measured by 3.
:: viscosity increase less than 5 seconds ○: viscosity increase 5 seconds to less than 10 seconds Δ: viscosity increase 10 seconds to less than 20 seconds ×: viscosity increase 20 seconds or more Practical level is ○ or more.

<Adhesiveness>
A cellophane tape was attached to the coated surface of the coating agent-coated material, and after pressure bonding with a finger five times, the tape was peeled off. The adhesion to the aluminum foil was evaluated from the comparison of the area where the tape was attached and the area where the coating agent coating film peeled off from the aluminum foil.
:: The coating film did not peel at all ○: The area where the coating film peeled from the aluminum foil is less than 20% of the tape adhesion area Δ: The area where the coating film peeled from the aluminum foil is 20% of the tape adhesion area More than 50% x: The area where the coating film is peeled from the aluminum foil is 50% or more of the tape adhesion area, and the practical level is ○ or more.

<Heat resistance>
The coated surface of aluminum foil and the surface coated with aluminum powder coated in the same size as the coated material are placed on top of each other and heat-sealed using a heat seal tester at a temperature of 300 ° C and a pressure of ² kg / cm ² for 1 second. The aluminum foil was pressed, and the aluminum foil and the coated surface of the coating agent coated material were peeled off. The heat resistance was evaluated from the comparison of the pressed area and the transfer area of the coating agent coating film to the aluminum foil after peeling.
:: There is no transfer of the coating film to the aluminum foil ○: The transfer area of the coating film to the aluminum foil is less than 20% of the pressed area Δ: The transfer area of the coating film to the aluminum foil is pressed 20% or more and less than 50% of x: 50% or more of the area of the transferred area of the coated film to the pressed aluminum foil The practical level is ○ or more.

  From the results of the examples, it was found that the present invention can provide a coating agent composition for PTP packages which does not release formaldehyde and has sufficient heat resistance. On the other hand, in the comparative example, the heat resistance was insufficient.

  The present invention can provide a coating composition for a PTP package which does not release formaldehyde and has sufficient heat resistance, and a PTP package using the coating composition. Therefore, the present invention is effective in a wide range of fields such as the PTP packaging field used for packaging pharmaceuticals and the like.

Claims (6)

A coating agent composition for a lid for PTP packaging, which has a laminated structure in the order of a coating agent layer, an aluminum foil and a heat seal layer,
The coating agent composition is a hydroxyl group-containing acrylic resin (A) having a hydroxyl value of 10 to 60 mg KOH / g (except in the case of the following resin (B)), and a hydroxyl group-containing silicone-modified acrylic resin A coating agent composition for a lid material for PTP packaging, comprising a resin (B) and a blocked polyisocyanate compound (C).   A hydroxyl group-containing silicone-modified acrylic resin (B) comprises a monomer (a) having an α, β-unsaturated double bond group and a polyorganosiloxane chain, and an α, β-unsaturated double bond group and a hydroxyl group (B) and a monomer (c) having an α, β-unsaturated double bond group (except in the case of the monomer (a) and the monomer (b)) The coating agent composition according to claim 1, wherein the monomer (a) is 1.5 to 5% by weight based on the total of the resin (A) and the resin (B). The coating agent composition according to claim 1 or 2, wherein the dissociation temperature of the blocking agent of the blocked polyisocyanate compound (C) is 90 ° C or less. A cover material for a TP package, which is obtained by applying the coating agent composition according to any one of claims 1 to 3 on an aluminum foil and thermally curing it. Furthermore, the lid material of Claim 4 which has a heat seal layer in the aluminum foil surface on the opposite side of a coating agent layer. A lid according to claim 5 , wherein the transparent plastic base material is heat sealed.