JP6527005B2 - Deodorant composition, external preparation for skin containing the deodorant composition - Google Patents

Description

  The present invention is a plant-derived deodorant composition that is effective against a wide range of unpleasant single odors and complex odors, is particularly safe for the human body, has excellent solubility in a base and is easy to handle. The present invention relates to a skin external preparation and a deodorant product.

Although sprays and wet tissues containing silica and magnesium oxide, which are cosmetic minerals, are distributed for the purpose of deodorizing sweat, moxibustion and foot odor, white floats on dark clothes such as black formal clothes and dark suits. Have problems.
In addition, as a plant-derived deodorant, green tea extract, dokudami extract, melon extract, lavender extract, persimmon leaf extract, mate extract and the like are known (Non-Patent Document 1) When the purpose is to deodorize body odor, there are many opportunities for direct contact with the skin, and safety to the skin is also required.

As another plant-derived deodorant, a sulfur-based malodor-selective deodorant (Patent Document 1) comprising Tangerine (Tangjin) or an extract of a closely related species thereof as an essential component has been proposed, and chrysanthemum flowers (Kikuka) ), Gold and silver (Kinjiinka), Dinji (Ginkgo), Yellow Gon (Ougon), Goubeiko (Gobaishi), Aoyu (Seitai), Gyoza (Binrouge), Deca Aiko (Ketmeishi), Apricot (Saujutsu), Licorice (Lancho) Although an aroma deodorant (Patent Document 2) and the like containing a crude drug extract of ice pieces (Gyotogen) has been proposed, the safety to these skins has not been verified.
As plant-derived deodorants for which safety to the skin has been confirmed, deodorants consisting of an extract of a mixture of touki, peony, senkyu and diow (Patent Document 3), touoki, peony, senkyu, diow and ginger A deodorant composition (Patent Document 4) comprising an extract of

Unexamined-Japanese-Patent No. 1-218457 Unexamined-Japanese-Patent No. 2-264663 Japanese Patent Application Publication No. 2007-325693 JP 2012-308 A

Fragrance Journal No.65 (Vol.12, No.2) (1984) Issued by Fragrance Journal

  However, there is a continuing demand for the provision of deodorants having improved deodorizing power, human safety and handleability as compared to existing deodorants. Body odor is a mixture of many odorous components, and the individual species and amounts of the components are large among individuals. Therefore, it has been pointed out that the existing deodorants do not provide deodorants that are less irritating to the skin and at the same time exert a deodorizing effect on a wide range of various body odors. It had been.

The present invention solves the above-mentioned problems in existing deodorants, and includes a wide range of body odors such as fatty acids having 2 to 12 carbon atoms, alcohols such as hexanol, unsaturated aldehydes such as 2-nonenal, etc. It is an object of the present invention to provide a useful deodorant composition that is effective for the ingredients, has no skin irritation, has good solubility in a base, is easy to handle, and has few problems such as coloring on clothes. Do.

  In order to solve the above-mentioned subject, the present inventors searched various plant extracts and their mixtures. As a result, focusing on the various herbal medicines used in the soup of Chinese medicine dish called Shishin-to (su-su-stain tongue), combining four herbal medicines uniquely formulated among them, the simultaneous extract from their mixture is synergistic The present invention has been accomplished by finding that the deodorizing effect is extremely excellent and there is no irritation to the skin.

That is, the present invention is as follows.
(1) A deodorant composition comprising, as an active ingredient, an extract of a mixture of rennik, kenjitsu, yokinin and sandalwood.
(2) The above-mentioned deodorant composition characterized in that the compounding ratio of rennik, kenjitsu, yokinin and birch in the mixture is 1 to 6: 1 to 6: 1 to 6: 1 to 6 in mass ratio.
(3) The above deodorant composition characterized in that the compounding ratio of rennik, kenjitsu, yokinin and birch in the mixture is 3-4: 3-4: 3-4: 3-4 by mass ratio.
(4) The above-mentioned deodorant composition characterized in that it is an extract of water or an alcohol or a mixture thereof.
(5) Extraction with water, ethanol, 1,3-butylene glycol, propylene glycol, dipropylene glycol, glycerin, diglycerin, 1,2-pentanediol, 1,3-propanediol or a mixture of two or more thereof The above-mentioned deodorant composition characterized in that
(6) The above-mentioned deodorant composition characterized in that it is an extract with an aqueous ethanol solution.
(7) The above-mentioned deodorant composition characterized in that the aqueous ethanol solution is a 10-90% aqueous solution.
(8) The above-mentioned deodorant composition characterized in that the amount of the extraction solvent is 10 to 100 times the total amount of the extract in mass ratio.
(9) The above-mentioned deodorant composition which is an external preparation directly applied to human skin and body hair by spraying or application.
(10) A skin external preparation comprising the above deodorant composition as an active ingredient.
(11) A deodorant product comprising the above deodorant composition as an active ingredient.
(12) The mixture ratio of rennik, kenjitsu, yokinin, and birch is 1 to 6: 1 to 6: 1 to 6: 1 to 6 in mass ratio, and the mass ratio is 10 to 10% of the total amount of the extract A method for producing a deodorant composition comprising extracting with 100 times amount of water or an alcohol or a mixture thereof.

According to the present invention, it is possible to provide a deodorant composition that exerts a deodorizing effect on a wide range of body odor components quickly and does not cause skin irritation.
In particular, since the deodorant composition of the present invention uses as raw materials plants conventionally used as herbal medicines and food raw materials, it can be taken not only as cosmetics and medicines but also as food.
Further, although it is conceivable to spray or apply directly to the skin because of the property of a body odor deodorant, it has traditionally been formulated with a herbal medicine that is considered good for the skin, and is designed with consideration for the skin.

Graph showing the results of skin irritation test [Test Example 2] of the product of the present invention Graph showing the rapid deodorizing effect of the product of the present invention on isovaleric acid Graph showing the rapid deodorizing effect of the product of the present invention on enanthate Graph showing the rapid deodorizing effect of the product of the present invention on 2-nonenal Graph showing the deodorizing effect on fatty acid (C 5-12 carbon) of the product of the present invention

[1] Deodorant Composition Plants used in the deodorant composition of the present invention are as follows, and any of leaves, stems, roots, flowers, seeds or whole grass can be used. Moreover, you may utilize the herbal medicine which originates in the following plant.
(1) Rennik Nelumbo nucifera (the lotus family)
(2) Kenjitsu Euryale forox SALIS B.
(3) Yokinin Coix lacryma-jobi Linn ever. Mayuen Stapf (Poaceae)
(4) Bitter gourd Lilium lancifolium Thunberg, Lilium brownie FE Brown var. Colchesteri Wilson, Lilium brownie FE Brown or Lilium pumilum De Candolle (Liliaceae)
The type of each herbal medicine is not limited to the above, and variants, congeners and other related species can also be used.

  Shishinyu is basically based on 4 types of rennik, kenjitsu, bokuryoou (Salnococcus sclerotisum), and sanyak (rhizome of pokeweed family), but in addition to yokinin, byakukou, kukoshi, jujube, hormone, etc., or The one that replaced some of the basic four herbal medicines is being eaten in areas such as Taiwan as medicinal soup. Shishin-to makes the spleen, stomach, kidneys and lungs healthy, and is said to enhance immunity (for example, "Let's eat this if you go to Taiwan!" Issued by Seibundo Shinkosha, February 18, 2015 version reference).

  In addition, rennik, kenjitsu, yokuinin is considered to have a beautifying effect and is one of the herbal medicines favored by women. In particular, Yokuinin has long been recognized as a good herbal medicine for skin in Japan and has been used for a long time ("Konso Komeme Kazuhiro Teiuchi's Inner Women's Fostering Face", written by Zhang Xiao-Wan, published by Gold Bull Culture Business Co., Ltd., 2010 11 Moon; "The Chinese Medicine Dictionary", published by Shanghai Science and Technology Publishing Company, Shogakukan, December 1985).

  In the present invention, each herbal medicine is mixed prior to extraction. The compounding ratio can be arbitrarily adjusted and used according to the purpose, but usually, the compounding ratio of rennik, kenjitsu, yokinin and sandalwood is 1 to 6: 1 to 6: 1 to 6: 1 by mass ratio. It is .about.6, preferably 3 to 4: 3 to 4: 3 to 4: 3 to 4. Typically, rennik, kenjitsu, yokinin and sandalwood are used at a blending ratio of 1: 1: 1: 1.

  The active ingredient is extracted from a mixture of these plants using an appropriate solvent. The solvent may be water, alcohols (eg, lower alcohols such as methanol, ethanol, propanol, isopropanol, etc., or 1,3-butylene glycol, propylene glycol, dipropylene glycol, glycerin, diglycerin, 1,2-pentanediol, 1 Polyhydric alcohols such as 3-propanediol) and the like can be used alone or as a mixture of two or more.

  It is preferable to use an aqueous ethanol solution as the extraction solvent used in the present invention, but in view of the preservative effect of the extract, the concentration is usually 10 to 90% (v / v), preferably It is used at 30 to 70% (v / v). If the ethanol concentration is less than 10% (v / v), anxiety will arise in terms of preservative effect.

  The amount of the extraction solvent used is preferably 10 to 100 times, particularly 15 to 50 times the total amount of the extract (rennik, kenjitsu, yokinin and sandalwood) by mass ratio.

  Although the temperature at the time of extraction is not particularly limited, it is usually carried out in a temperature range of 0 to 150 ° C., preferably 20 to 100 ° C., more preferably 25 to 80 ° C. When the extraction temperature is less than 0 ° C., extraction may take time, and when the extraction temperature exceeds 150 ° C., it may cause turbidity and the like.

  The present invention is characterized in that all four types of each herbal medicine are mixed and then extracted, but (1) a method of extracting and mixing each of the plants, and (2) some of rennik, kenjitsu, yokinin and birch gauw Compared with the method of mixing the one extracted at the same time and the one extracted separately, the one extracted after blending all four types is advantageous in that the generation of a precipitate due to aging is less, and The synergetic effect of the four types of herbal medicines can provide an excellent deodorizing effect.

[2] Skin external preparation The skin external preparation according to the present invention is produced by using the above-mentioned deodorant composition in combination with, for example, a base, an additive, etc. which are usually used in cosmetics as shown below. be able to.

  (1) Various fats and oils: avocado oil, almond oil, bilberry oil, sesame oil, olive oil, olive oil, orange oil, orange raffi oil, sesame oil, cocoa butter, chamomile oil, carrot oil, cucumber oil, beef tallow fatty acid, kucunut oil, safflower Oil, shea butter, liquid shea butter, soybean oil, camellia oil, corn oil, rapeseed oil, persic oil, castor oil, castor oil, cottonseed oil, peanut oil, turtle oil, mink oil, egg yolk oil, palm oil, palm kernel oil, coconut oil , Beef tallow, pork fat or hydrogenated products of these fats and oils (hardened oil etc.).

  (2) Waxes: beeswax, locust wax, carnauba wax, spermaceti wax, lanolin, liquid lanolin, reduced lanolin, hard lanolin, candelilla wax, montan wax, shellac wax, rice wax, squalene, squalane, pristane and the like.

  (3) Mineral oil: liquid paraffin, petrolatum, paraffin, ozokeride, ceresin, microcrystalline wax and the like.

  (4) Fatty acids: Natural fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, 12-hydroxystearic acid, undecylenic acid, tall oil fatty acid, lanolin fatty acid, isononanoic acid, caproic acid, Synthetic fatty acids such as 2-ethylbutanoic acid, isopentanoic acid, 2-methylpentanoic acid, 2-ethylhexanoic acid, isopentanoic acid and the like.

  (5) Alcohols: Natural alcohols such as ethanol, isopropanol, lauryl alcohol, cetanol, stearyl alcohol, oleyl alcohol, lanolin alcohol, cholesterol, and phytosterol, and synthetic alcohols such as 2-hexyldecanol, isostearyl alcohol and 2-octyldodecanol.

  (6) Polyhydric alcohols: ethylene glycol, diethylene glycol, triethylene glycol, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, polyethylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, 1,3-butylene glycol, 1,2-pentanediol, glycerin, diglycerin, pentaerythritol, sorbitol, mannitol and the like.

  (7) Esters: isopropyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, oleyl oleate, decyl oleate, octyldodecyl myristate, hexyl decyl dimethyl octanoate, cetyl lactate, myristyl lactate , Diethyl phthalate, dibutyl phthalate, lanolin acetate, ethylene glycol monostearate, propylene glycol monostearate, propylene glycol dioleate and the like.

  (8) Metal soaps: aluminum stearate, magnesium stearate, zinc stearate, calcium stearate, zinc palmitate, magnesium myristate, zinc laurate, zinc undecylenate and the like.

  (9) gum, saccharides or water-soluble polymer compounds: gum arabic, benzoin gum, dammar gum, guaiac fat, irish candy, karaya gum, tragant gum, carob gum, quinseed, agar, casein, lactose, fructose, sucrose or ester thereof , Trehalose or derivatives thereof, dextrin, gelatin, pectin, starch, carrageenan, carboxymethyl chitin or chitosan, hydroxyalkyl (C2 to C4) chitin or chitosan having an alkylene (C2 to C4) oxide such as ethylene oxide added, low molecular weight Chitin or chitosan, chitosan salt, sulfated chitin or chitosan, phosphorylated chitin or chitosan, alginic acid or salt thereof, hyaluronic acid or salt thereof, chondroitin sulfate or salt thereof, heparin, ethyl cellulose, methyl cellulose , Carboxymethyl cellulose, carboxyethyl cellulose, sodium carboxyethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, nitrocellulose, crystalline cellulose, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, polyvinyl methacrylate, polyacrylate, polyethylene oxide, polypropylene oxide, etc. Polyalkylene oxides or cross-linked polymers thereof, carboxyvinyl polymers, polyethyleneimines and the like.

  (10) Surfactants: anionic surfactants (alkyl carboxylates, alkyl sulfonates, alkyl sulfates, alkyl phosphates), cationic surfactants (alkyl amines, alkyl quaternary ammonium salts), Amphoteric surfactant [Carboxylic acid type amphoteric surfactant (amino type, betaine type), sulfuric acid ester type amphoteric surfactant, sulfonic acid type amphoteric surfactant, phosphoric acid ester type amphoteric surfactant], nonionic surfactant Agents (ether type nonionic surfactant, ether ester type nonionic surfactant, ester type nonionic surfactant, block polymer type nonionic surfactant, nitrogen containing type nonionic surfactant), other surface active agents Agents (natural surfactants, derivatives of protein hydrolysates, polymeric surfactants, surfactants containing titanium and silicon, Carbon-based surface active agent), such as.

  (11) Various vitamins Vitamin A group: retinol, retinal (vitamin A1), dehydro retinal (vitamin A2), carotene, lycopene (provitamin A), vitamin B group: thiamine hydrochloride, thiamine sulfate (vitamin B1), Riboflavin (vitamin B2), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12), folates, nicotinic acids, pantothenic acids, biotins, choline, inositols, vitamin C group: vitamin C acid or derivatives thereof, vitamin D group: Ergocalciferol (vitamin D2), cholecalciferol (vitamin D3), dihydrotachysterol, vitamin E group: vitamin E or derivatives thereof, ubiquinones, vitamin K group: phytonadione (vitamin K1), menaquinone (vitamin K2), Menadione (vitamin K3), menadiol (vitamin K4), other essential fatty acids (vitamin F), carnitine, ferulic acid, γ-oryzanol, orotic acid, vitamin Ps (rutin, eriocitrin, hesperidin), vitamin U and the like.

  (12) Various amino acids: valine, leucine, isoleucine, threonine, methionine, phenylalanine, tryptophan, lysine, glycine, alanine, asparagine, glutamine, serine, cysteine, cystine, tyrosine, proline, hydroxyproline, aspartic acid, glutamic acid, hydroxy Lysine, arginine, ornithine, histidine etc. and their sulfates, phosphates, nitrates, citrates or amino acid derivatives such as pyrrolidone carboxylic acid etc.

  (13) Various additives derived from plant or animal raw materials: These are processed according to the type and form of the product to be added in a conventional manner (eg, grinding, milling, washing, hydrolysis, fermentation, Purification, squeezing, extraction, fractionation, filtration, drying, powdering, granulation, dissolution, sterilization, pH adjustment, deodorization, decolorization, etc. are arbitrarily selected and combined) and any of various materials is selected. It should be provided as

  The solvent used for extraction of the above plant or animal material may be selected in consideration of the purpose of use, type of the product to be provided, or processing to be performed later, etc., but in general, water and water It is desirable to use a mixture of one or more selected from organic solvents such as ethanol, propylene glycol, 1,3-butylene glycol and the like. However, when the content of the organic solvent is not preferable depending on the use, it is sufficient to use only water, or to employ ethanol which is easy to remove after extraction, and use it alone or in any mixture with water. It may be the one extracted and extracted.

  When the additive derived from the plant or animal material is applied to an external preparation for systemic use or topical use, cosmetics, the protection of the skin and hair, moisturizing, improvement of feel and feel, impartation of softness, Alleviation of irritation, alleviation of stress due to aroma, cell activation (cell aging prevention), suppression of inflammation, improvement of skin and hair quality, prevention of rough skin and improvement thereof, hair growth, hair growth, hair loss prevention, addition of gloss, cleaning effect In addition to cosmetic effects such as relieving fatigue, blood flow promotion, and bathing effects, other effects such as incense, deodorization, thickening, preservatives and buffering can also be expected.

  (14) Flavoring agents: Natural animal flavorings such as musk, civette, kathrium, ambergris, anise essential oil, angelica essential oil, ylang ylang essential oil, iris essential oil, fennel essential oil, orange essential oil, cananga essential oil, caraway essential oil, cardamom essential oil, guaiac wood essential oil , Cumin essential oil, black letters essential oil, cinnamon essential oil, cinnamone essential oil, geranium essential oil, copaiba balsam essential oil, coriander essential oil, shiso essential oil, cedarwood essential oil, citronella essential oil, jasmine essential oil, gingergrass essential oil, cedar essential oil, spearmint essential oil, Daigo incense essential oil, tuberose essential oil, clove essential oil, orange flower essential oil, winter green essential oil, torubalsam essential oil, patchouli essential oil, rose essential oil, palma rosa essential oil, persimmon essential oil, hiba essential oil, birch essential oil, puchigren essential oil, bay essential oil, vetiver essential oil, berga Vegetable flavors such as persimmon essential oil, peru balsam essential oil, boad rose essential oil, rich essential oil, mandarin essential oil, eucalyptus essential oil, eucalyptus essential oil, lime essential oil, lavender essential oil, linaloe essential oil, lemon grass essential oil, lemon grass essential oil, lemon essential oil, rosemary essential oil, Japanese peppermint essential oil Such.

  Synthetic perfume ingredients include hydrocarbons such as aliphatic hydrocarbons, terpene hydrocarbons and aromatic hydrocarbons, alcohols such as aliphatic alcohols, terpene alcohols and aromatic alcohols, ethers such as aliphatic ethers and aromatic ethers , Aliphatic oxides, oxides of terpene oxides, aliphatic aldehydes, terpene aldehydes, hydrogenated aromatic aldehydes, thioaldehydes, aldehydes such as aromatic aldehydes, aliphatic ketones, terpene ketones, hydrogenated aromatic compounds Aliphatic ketones, aliphatic cyclic ketones, non-benzene aromatic ketones, ketones such as aromatic ketones, acetals, ketals, phenols, phenol ethers, fatty acids, terpene carboxylic acids, hydrogenated aromatic carboxylic acids, Acids such as aromatic carboxylic acids, acid amides, aliphatic lactones Macrocyclic lactone, terpene series lactone, hydrogenated aromatic lactone, lactones such as aromatic lactone, aliphatic esters, carboxylic acid family esters of furan series, esters such as aliphatic cyclic carboxylic acid esters, aromatic carboxylic acid esters Nitromusk, nitrile, amine, pyridines, quinolines, nitrogen-containing compounds such as pyrrole, indole and the like. More specific examples of synthetic flavors include, for example, Chemical Chemical Daily, 1996, Motoichi Into (Synthetic Flavor Chemistry and Commodity Knowledge), 1969, Stephan Arctander (STEFFEN ARCTAMDER) (Puffum and Fleber Chemicals <Perfume and The fragrance etc. which were described in <Flavor Chemicals> etc. can be used suitably.

  The main flavors are shown below. Aldehydes C6 to C12, anisaldehyde, acetal R, acetophenone, acetyl cedrene, adoxyl, allyl amyl glycolate, allyl cyclohexane propionate, alpha damascone, beta damascone, delta damascone, ambretlid, ambroxane, amyl Cinnamic aldehyde, amyl cinnamic aldehyde dimethyl acetal, amyl valerianate, amyl salicylate, iso amyl acetate, iso amyl salicylate, auranthiol, acetyl ugenol, bacdanol, benzyl acetate, benzyl alcohol, benzyl alcohol, benzyl salicylate, bergamil acetate, bornyl acetate , Butyl butyrate, para-tert-butyl cyclohexanol, para-tert-butyl ester Lohexyl acetate, ortho tertiary butyl cyclohexanol, benzaldehyde, benzyl formate, cariolefin, kashmelan, carvone, sedoroamber, sedolyl acetate, cedrol acetate, cerythroid, cinnamic alcohol, cinnamic aldehyde, cisjasmon, citral, citral Dimethyl acetal, citrosal, citronellol, citronellyl acetate, citronellyl formate, citronellyl nitrile, cyclaset, cyclamenaldehyde, cyclaprop, caron, coumarin, cinnamyl acetate, delta C6 to C13 lactone, dimethyl benzyl carbinol, dihydrojasmon , Dihydrolinalool, dihydromyrcenol, dimethol, dimyrsetol, dif Nil oxide, ethyl crocodilene, jugenol, fluitate, fenkyl alcohol, phenylethyl phenyl acetate, galaki solid, gamma C6 to C13 lactone, geraniol, geranyl acetate, geranyl formate, geranyl nitrile, hedion, helional, heliotropin, cis-3-hexenol , Cis-3-hexenyl acetate, cis-3-hexenylulsalicylate, hexyl cinnamic aldehyde, hexyl salicylate, hyacinth dimethyl acetal, hydrotropic alcohol, hydroxycitronellal, indole, isobornyl acetate, isocyclocitral, iso E Super, isojugenol, isononyl acetate, isobutyl quinoline, jasmar, jasmolact And jasmophilan, coabon, ligstral, liliar, lime oxide, limonene, linalool, linalool oxide, linalyl acetate and the like.

  Furthermore, in addition to the above, each raw material known so far, for example, α-hydroxy acids, inorganic pigments, ultraviolet light absorbers, whitening agents, tyrosinase activity inhibitors, melanin pigment decomposition substances, cell activating substances, astringents , Active oxygen scavenging agent, antioxidant, antiglycation, lipid peroxide formation inhibitor, anti-inflammatory agent, antibacterial agent, moisturizing agent, elastase activity inhibitor, antiandrogenic agent, warming agent, cooling agent, pigment, hormone Sequestering agents, pH adjusters, chelating agents, preservatives / biocides, refreshing agents, stabilizers, emulsifiers, animal and animal proteins or their degradation products, animal and vegetable polysaccharides or their decomposition products, It can be used in combination with animal and plant glycoproteins or their degradation products, anti-inflammatory agents / anti-allergic agents, wound healing agents, foams / foamers, thickeners, oral agents, deodorants / deodorants, enzymes etc. .

  In the skin external preparation in which the deodorant composition of the present invention is used, the deodorant composition contains about 0.0001 to 5% by mass, preferably about 0.001 to 1% by mass as a dry extract. When it is used, it is easy to use and good effects can be obtained. As a specific example of the skin external preparation in the present invention, the following deodorizing products are mentioned.

[3] Deodorant Product The deodorant product in which the deodorant composition of the present invention is used is not particularly limited as long as a deodorant effect is required, and, for example, a cosmetic composition for deodorant Products, bath compositions, detergent compositions and other products, each of which is exemplified by liquid, emulsion, paste, gel, powder (powder), granular, pellet, stick, solid, etc. It may be provided in any form.

  Deodorant cosmetic compositions include deodorant sprays, lotions, emulsions, creams, oils, ointments, packs, lips, lipsticks, foundations, eyeliners, blushers, mascaras, eye shadows, manicures and pedicures, Nail coating agent, nail coating remover, shaving agent, shampoo, rinse, hair treatment, hair tonic, hair spray, hair cream, hair lotion, hair setting agent, hair growth agent, permanent solution, hair dye, hand soap, body soap Toothpaste, mouthwash, face wash, soaps and the like. In the deodorant cosmetic composition of the present invention, the deodorant composition of the present invention is used in the range of 0.001 to 99% by mass, preferably in the range of 0.1 to 30% by mass.

  The bath agent composition is used by being poured into bath water at the time of bathing, and may be in any form such as liquid, powder, granular, solid and the like. When in the form of powder, granules or solid, it is possible to produce the deodorant composition of the present invention by spraying it in a liquid state and drying it without drying. In the bath agent composition of the present invention, the deodorant composition of the present invention is usually used in the range of 0.00001 to 99% by mass, preferably in the range of 0.0001 to 30% by mass as a dry extract. And more preferably in the range of 0.001 to 10% by mass.

  Detergent compositions include detergents for clothing, fabric softeners, clothing products such as laundry paste, kitchen detergents used on a daily basis, bath, washroom or toilet detergents, glass cleaners, eyeglasses and contact lenses cleaning Agents, car cleaners, building materials cleaners etc. In the detergent composition of the present invention, the deodorant composition of the present invention is used in the range of 0.001 to 99% by mass, preferably in the range of 0.1 to 30% by mass.

Other products include the following.
Household products sprayed or applied with the deodorant composition of the present invention, such as futon and duvet covers, sheets, blankets and blanket covers, pillows and pillow covers, tatami mats, fittings, towels and the like.
Deodorant composition of the type used by spraying on indoor fragrances / deodorants, toilet fragrances / deodorants, automotive fragrances / deodorants, clothes / furniture, etc.
A medical deodorant composition used for a hospital, a doctor's office, a clinic, a curtain for a sick room, bedding for a sick room, a nursing home, care products and the like.
Deodorant composition used in public institutions and facilities such as interior products for railways, buses, taxis, hires, aircraft and ships, and public toilets.
Deodorant composition used for sanitary products, wet type tissue paper, non-woven fabric, paper towel, cotton and the like.

  The present invention will be described below with reference to production examples, test examples and formulation examples, but the present invention is not limited thereto.

Example 1 (Production Example 1)
Water (500 ml) was added to a mixture of 5 g of rennik, 5 g of kenjitsu, 5 g of yokinin and 5 g of sandalwood and extracted under reflux for 1 hour. Next, this is filtered to obtain an extract, and the extract is further concentrated and dried to extract the deodorant composition of the present invention as a light brown powder.
I got .5g.

Example 2 (Production Example 2)
Water (500 l) was added to 5 kg of rennik, 5 kg of kenjitsu, 5 kg of yokinin, and 5 kg of sandalwood, and immersion extraction was performed overnight. Next, this was filtered to obtain an extract, and further concentrated and dried to obtain 2.5 kg of the deodorant composition of the present invention as a light brown powder.

Example 3 (Production Example 3)
200 liters of ethanol and 300 liters of water were added to 5 kg of rennik, 5 kg of kenjitsu, 5 kg of yokinin, and 5 kg of sandalwood, and immersion extraction was performed overnight. Then, it was filtered to obtain 495 kg of a slightly yellowish extract as a deodorant composition of the present invention.

Comparative Example 1 (Production Example 4)
To 20 g of commercially available green tea leaves, 200 ml of ethanol and 300 ml of water were added, and immersion extraction was performed overnight. Then, this was filtered to obtain 495 g of a slightly yellowish extract as the deodorant composition of Comparative Example 1.

[Test Example 1] Safety test Evaluation of skin irritation 1
In order to evaluate the skin irritation of the deodorant composition of the present invention, a closed method patch test was conducted by continuous 24-hour application with a monitor of 20 healthy people (men and women aged 20 to 60).
(sample)
1: The deodorant composition of Example 1 was diluted with distilled water to adjust the solid content to 5% by mass. 2: The deodorant composition of Example 2 was diluted with distilled water, and the solid content was 5% by mass. : 3. The deodorant composition of Example 3 was concentrated and adjusted to a solid content of 5% by mass (method)
Using a patch tape for skin test (patch tester "Torii" Torii Pharmaceutical Co., Ltd. product) filled with 0.03 ml of the sample, it was judged by sticking for 24 hours on the back of the subject. That is, the sample was removed at 24 hours after the application, and the condition of the skin was observed for each determination. (Judgment criteria) Judgment was performed by the following criteria.
(+) Positive: clear erythema (±) weak positive: slight erythema (-) negative: no response The results are shown in Table 1.

  From Table 1, the deodorizing composition according to the present invention did not show any skin irritation.

[Test Example 2] Safety test Evaluation of skin irritation 2
In order to evaluate the skin irritation of the deodorant composition of the present invention, a skin application test was conducted on 24 healthy people (females aged 30 to 49) with a monitor.
(sample)
4: Deodorant composition obtained in Example 3.
(Method)
The samples were concentrated, and those prepared to have a solid content of 5% by mass were applied twice daily as morning and evening on a monitor as a lotion, and the state change was observed by visual observation for 4 weeks and a questionnaire survey on the monitor. As a control, 5% by mass ethanol aqueous solution was used. In addition, as physical measurement, measurement of skin water content was performed in parallel with SKICON-200EX. The results are shown in FIG.

  As a result of the above test, no skin adverse event occurred in all 24 monitors, but rather a significant improvement was observed in the skin roughness (drying) of the questionnaire compared to the control group. This is also supported by the result that the skin moisture amount of the monitor increased as a result of FIG.

[Test Example 3] Deodorizing effect on malodor component Deodorization of the present invention is known for acetic acid, isovaleric acid, enanthate, pelargonic acid, capric acid, lauric acid and 2-nonenal known as malodor components of body odor. The effect was tested.
(Sample) 5: The deodorant composition obtained in Example 3 was concentrated to adjust the solid content to 8% by mass.
(Method) A 100 ppm aqueous solution of each of the above malodorous components was prepared, and 0.5 ml was put in a 20 ml vial to make a malodor target. After adding 0.5 ml of samples to this and incubating it at 40 degreeC for 10 minutes, the head space was extract | collected and it measured by GC-MS. Evaluation made the measured value of the offensive odor component in the blank (distilled water) 100, and made the relative measured value the residual rate. Further, a commercially available green tea extract (Fresh E: manufactured by Shirai Matsushinyaku Co., Ltd.) was similarly measured as Reference Product 1. The results are shown in Table 2.

  From the results of Table 2, the deodorant of the present invention exhibited superior effects as compared to the commercially available green tea extract.

[Test Example 4] Measurement of immediate effect The immediate effect of the deodorizing effect of the present invention was tested on isovaleric acid, enanthate and 2-nonenal which are known as malodorous components of body odor. The method was performed according to the method published in the 58th debate on perfume, terpene and essential oil chemistry.
(sample)
6: What concentrated the deodorant composition obtained in Example 3 and adjusted it to 8 mass% of solid content.
(Method)
A 100 ppm aqueous solution of each of the above-mentioned malodorous components was prepared, and 9.5 ml was put in a 20 ml vial to make it an odor. To this was added 0.5 ml of a sample, and while passing air at 200 ml / min, the odor in the gas phase was continuously measured for 10 minutes with a soft ionization mass spectrometer (* AirSense (Alpha MOS)). In the evaluation method, the measured value when no sample was added was taken as 100, and the relative measured value every 0.3 seconds was taken as the remaining rate. Distilled water was added as a control. The results are shown in FIGS.

  From the results of FIGS. 2 to 4, it is found that the deodorant composition of the present invention shows a rapid deodorizing effect on malodorous substances, and in particular, a remarkable deodorizing effect on 2-nonenal within 2 minutes. It has been shown.

[Test Example 5] Deodorizing effect on malodor of multi-component system A simulated sweat odor composition was prepared, and the immediate effect of the deodorizing effect of the present invention was evaluated by a sensory test.
(sample)
7: Deodorant composition obtained in Example 3.
(Method)
The simulated sweat odor composition in Table 3 was prepared, and a 62.5 ppm aqueous solution was prepared. To 5 ml of this aqueous solution, 15 mg of the deodorant composition of Example 3 was added in terms of solid content, and sensory evaluation was performed by 62 skilled panelists. As a standard product, 15 mg of a 40% ethanol aqueous solution was used, and as a comparative example, 15 mg of the deodorant composition of Production Example 4 as a solid content was used.
Evaluation criteria are as follows.
Evaluation point 4: equivalent to standard product Evaluation point 3: smell slightly weaker than standard product Evaluation point 2: smell weaker than standard product Evaluation point 1: very weak odor than standard product Evaluation score 0: odor of simulated sweat odor The average score is shown in Fig.5.

  The results shown in FIG. 5 indicate that the deodorant composition of the present invention is also significantly effective against combined malodor.

Preparation of Various Skin External Composition (Deodorant Product) Various skin external compositions according to the present invention were manufactured. Although the formulation example is shown below, this invention is not limited to these. All prescription examples are shown in mass%.

Example 4
According to the following formulation example, cosmetic obtained by mixing, at room temperature, purified water with a moisturizing agent such as 1,3-butylene glycol and glycerin, a skin nutrient such as oleyl alcohol, and an ethyl alcohol in which a preservative, a fragrance and the like are dissolved. 0.3% of the deodorant composition of Example 1 was added to the base to prepare a lotion of the present invention.

[Example 5]
A room-use deodorant a (liquid type) was prepared according to the following formulation.

[Example 6]
The indoor deodorizer b (liquid type) was prepared according to the following formulation.

[Example 7]
An indoor deodorant c (liquid type) was prepared according to the following formulation.

[Example 8]
An automotive deodorant (liquid type) was prepared according to the following formulation.

[Example 9]
A toilet deodorant (liquid type) was prepared according to the following formulation.

[Example 10]
Bath agent a (liquid type) was prepared according to the following formulation.

[Example 11]
Bath agent b (powder type) was prepared according to the following formulation.

[Example 12]
An antiperspirant (deodorant spray) was prepared according to the following formulation.

[Example 13]
Body soap was prepared according to the following formulation.

Example 14
The hygienic article of the present invention was prepared by spraying the deodorant composition of Example 3 on a commercial disposable napkin until the entire area of the napkin was wet and then drying.

  The deodorant of the present invention is effective against a wide range of malodorous components such as fatty acids having 2 to 12 carbon atoms, alcohols such as hexanol, and unsaturated aldehydes such as 2-nonenal, and there is no skin irritation and dissolution Can provide useful deodorizers that are easy to handle, easy to handle, and have few problems such as coloring

Claims (7)

  A deodorant composition comprising as an active ingredient an extract of a mixture of rennik, kenjitsu, yokinin and sandalwood.   The deodorant composition according to claim 1, characterized in that the compounding ratio of rennik, kenjitsu, yokinin and birch in the mixture is 1 to 6: 1 to 6: 1 to 6: 1 to 6 in mass ratio. object.   The deodorant composition according to claim 1, characterized in that the compounding ratio of rennik, kenjitsu, yokinin and birch in the mixture is 3-4: 3-4: 3-4: 3-4 in mass ratio. object. The deodorant composition according to any one of claims 1 to 3 , which is an external preparation directly applied to human skin and body hair by spraying or application. The skin external preparation containing the deodorizer composition of any one of Claims 1-4 as an active ingredient. A deodorant product comprising the deodorant composition according to any one of claims 1 to 4 as an active ingredient.   10 to 100 times the total amount of extractables in a mass ratio of a mixture in which the blending ratio of rennik, kenjitsu, yokinin, and birch is 1 to 6: 1 to 6: 1 to 6: 1 to 6 in mass ratio A method for producing a deodorant composition comprising extracting with water or an alcohol of the present invention or a mixture thereof.

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