JP6594114B2 - Multi-agent hair treatment agent and hair treatment method - Google Patents

Description

  The present invention relates to a multi-component hair treatment agent and a hair treatment method using the multi-component hair treatment agent.

  Protein derivatives such as hydrolyzed proteins are known as hair protection and repair components, and various treatments using the derivatives have been proposed. Patent Document 1 uses a hair modifying agent having a hair cosmetic containing soluble keratin added with an anionic surfactant as a first agent and a hair cosmetic containing a nonionic surfactant as a second agent. It is disclosed to fix soluble keratin on and inside the hair. Patent Document 2 discloses that penetration of hydrolyzed keratin into hair is promoted by containing a specific diester together with hydrolyzed keratin. Patent Document 3 discloses that hair repair by a specific protein derivative is improved by blending leucine.

JP-A-8-109114 JP 2013-53171 A Japanese Patent Laying-Open No. 2015-81245

  As described above, there are hair treatment proposals using protein derivatives. Further, hydrolyzed keratin and hydrolyzed keratin derivatives are known as keratin derivatives that are protein derivatives, and it is expected that the feel of hair can be adjusted if the permeability to these hairs can be controlled.

  In view of the above circumstances, an object of the present invention is to provide a multi-component hair treatment agent and a hair treatment method capable of controlling the permeability of hydrolyzed keratin and its derivatives to hair.

  As a result of intensive studies by the present inventors, if a treatment containing tannic acid is applied to the hair before applying the treatment containing hydrolyzed keratin or a derivative thereof to the hair, hydrolyzed keratin and its It has been found that it is possible to control the penetration of the derivative into hair, and the present invention has been completed.

  That is, the multi-component hair treatment agent according to the present invention is characterized by including a pretreatment agent containing tannic acid and a posttreatment agent containing hydrolyzed keratin or a hydrolyzed keratin derivative.

  It is preferable that hydrolyzable tannin is blended as tannic acid in the pretreatment agent.

As the hydrolyzed keratin derivative in the post-treatment agent, one having one or more side chain groups having units selected from the structures represented by the following formulas (I) to (III) and salts of these structures: It should be blended.
_{-S-S- (CH 2) n} -COOH (I)
(In the formula (I), n is 1 or 2.)
_{-S-S-CH (CH 3} ) -COOH (II)
_{-S-S-CH (COOH)} -CH 2 -COOH (III)

  The hair treatment method according to the present invention comprises a pretreatment step of applying a pretreatment agent containing tannic acid to hair, and a posttreatment agent containing hydrolyzed keratin or a hydrolyzed keratin derivative after the pretreatment step. And a post-treatment step applied to the hair.

  According to the present invention, after applying the pretreatment agent containing tannic acid to the hair, and then applying the posttreatment agent containing hydrolyzed keratin or a derivative thereof to the hair, the hydrolyzed keratin and the derivative thereof are applied to the hair. The permeability of is suppressed.

It is the picked-up image which observed the cut surface of the hair which performed the hair treatment of the Example by the fluorescence microscope. It is the picked-up image which observed the cut surface of the hair which performed the hair treatment of the comparative example by the fluorescence microscope.

Based on an embodiment of the present invention, the present invention will be described below.
The multi-component hair treatment agent of this embodiment comprises a pretreatment agent and a posttreatment agent used after the pretreatment agent.

(Pretreatment agent)
The pretreatment agent according to this embodiment is obtained by blending tannic acid with water (the blending amount of water is, for example, 25% by mass or more). Moreover, the raw material for well-known hair treatment agents may be mix | blended with the pretreatment agent of this embodiment as an arbitrary raw material according to a use.

Tannic acid Commercially available tannic acid or a plant extract containing tannic acid may be added to the pretreatment agent of the present embodiment.

  It is preferable that hydrolyzable tannin is blended as the tannic acid. Here, hydrolyzable tannin is an ester bond between glucose and gallic acid, and a depside bond between the ester bond and gallic acid. This hydrolyzable tannin is represented by the following general formula (A), for example.

[In the general formula (A), G represents a gallic acid residue after an ester bond or a depside bond, and k, l, m, and n each represent 0 or a positive integer. ]

  The blending amount of tannic acid in the pretreatment agent of this embodiment is preferably 0.1% by mass or less, preferably 0.05% by mass or less, and preferably 0.02% by mass or less in order to make the pretreatment agent inexpensive. Is more preferable. Moreover, the compounding quantity of a tannic acid may be trace amount, and the compounding quantity is 0.005 mass%, for example, 0.008 mass% or more is good, and 0.01 mass% or more is preferable.

Optional raw materials The optional raw materials blended in the pretreatment agent of the present embodiment are appropriately selected from known raw materials for hair treatment agents. These optional raw materials are surfactants, higher alcohols, polyhydric alcohols, saccharides, ester oils, fats and oils, fatty acids, hydrocarbons, waxes, silicones, polymer compounds, amino acids, animal and plant extracts, microorganism-derived substances, inorganic compounds, and fragrances. , Antiseptics, sequestering agents, UV absorbers and the like. The pretreatment agent may contain hydrolyzed keratin and / or hydrolyzed keratin derivative.

Dosage Form The pretreatment agent of the present embodiment is preferably an aqueous one whose outer phase is an aqueous phase in order to make it easier to adjust to hair. And the dosage form at the time of use of the said pretreatment agent is not specifically limited, For example, liquid form, cream form, gel form, foam form (foam form), and mist form are mentioned.

pH
The pH of the pretreatment agent of the present embodiment is, for example, 4 or more and 7 or less, and preferably 5 or more.

(Post-treatment agent)
The post-treatment agent according to this embodiment is hydrolyzed keratin, hydrolyzed keratin derivative, or hydrolyzed keratin and hydrolyzed keratin derivative blended in water (the blending amount of water is, for example, 25% by mass or more) ). Moreover, the raw material for well-known hair treatment agents may be mix | blended with the post-treatment agent of this embodiment as an arbitrary raw material according to a use.

Hydrolyzed keratin, hydrolyzed keratin derivative The “hydrolyzed keratin” in the present embodiment is based on the international labeling name created in accordance with the International Nomenclature Cosmetic Ingredient. The component which gave the display name "hydrolysis keratin" corresponds. Further, the “hydrolyzed keratin derivative” is a keratin derivative that does not correspond to the hydrolyzed keratin and is produced with cleavage of the main chain of keratin. These hydrolyzed keratin and hydrolyzed keratin derivative are preferably derived from wool that is easily available in a stable manner.

Examples of the hydrolyzed keratin derivative include a side chain having a unit selected from the structures represented by the following formulas (I) to (III) and salts of these structures disclosed in JP2012-224573A The thing provided with 1 type or 2 types or more of group is mentioned.
_{-S-S- (CH 2) n} -COOH (I)
(In the formula (I), n is 1 or 2.)
_{-S-S-CH (CH 3} ) -COOH (II)
_{-S-S-CH (COOH)} -CH 2 -COOH (III)

  The smaller the molecular weight of the hydrolyzed keratin and hydrolyzed keratin derivative, the more easily it penetrates into the hair and the effect on the solubility when the pH of the post-treatment agent is set low. Therefore, the hydrolyzed keratin and the hydrolyzed keratin derivative may contain those having a molecular weight of 20000 or less, preferably those having a molecular weight of 10,000 or less, and preferably those having a molecular weight of 5000 or less. . On the other hand, in order to suppress the permeability to hair, the hydrolyzed keratin and hydrolyzed keratin derivative preferably contain those having a molecular weight of 500 or more, preferably those having a molecular weight of 1000 or more. More preferably 2000 or more are included. Here, with respect to the molecular weight, the molecular weight calculated from the relative distance between the band of hydrolyzed keratin and the like and the molecular weight marker band by Sodium Dodecyl Sulfate-polyacrylamide gel electrophoresis (SDS-PAGE method) The molecular weight is considered to be adopted.

  In the post-treatment agent of this embodiment, one or more selected from hydrolyzed keratin and derivatives thereof are blended. The blending amount of hydrolyzed keratin and its derivative in this post-treatment agent is, for example, 0.0005 mass% or more, preferably 0.001 mass% or more, and preferably 0.01 mass% or more. On the other hand, the upper limit of the blending amount is preferably 1% by mass and preferably 0.1% by mass from the viewpoint of making the post-treatment agent inexpensive.

Arbitrary raw material The arbitrary raw material mix | blended with the post-processing agent of this embodiment is suitably selected from the raw material for well-known hair processing agents. These optional raw materials are surfactants, higher alcohols, polyhydric alcohols, saccharides, ester oils, fats and oils, fatty acids, hydrocarbons, waxes, silicones, polymer compounds, amino acids, animal and plant extracts, microorganism-derived substances, inorganic compounds, and fragrances. , Antiseptics, sequestering agents, UV absorbers and the like. In addition, although tannic acid may be mix | blended with the post-processing agent of this embodiment, the compounding quantity is good to make it smaller than the compounding quantity of a pre-processing agent (for example, 1/100 or less of the compounding quantity of a pre-processing agent) ).

Dosage Form The post-treatment agent of this embodiment is preferably an aqueous one in which the outer phase is an aqueous phase in order to make it easier to adjust to the hair. And the dosage form at the time of use of the said post-processing agent is not specifically limited, For example, liquid form, cream form, gel form, foam form (foam form), and mist form are mentioned.

pH
The pH of the post-treatment agent of this embodiment is, for example, 4 or more and 7 or less. When the pH is set low, when the dispersibility of the hydrolyzed keratin and / or hydrolyzed keratin derivative is low, the pH is preferably 5 or more, and preferably 6 or more.

(how to use)
The multi-component hair treatment agent of the present embodiment is a post-treatment step of applying a post-treatment agent after washing the pre-treatment agent or without washing off the pre-treatment agent after the pre-treatment step of applying the pre-treatment agent to the hair. Used in. The post-treatment agent may be washed off after application or not.

  The multi-component hair treatment agent of this embodiment may include one or more other treatment agents in addition to the pre-treatment agent and the post-treatment agent. For example, the order of use of other treatment agents after three-component hair treatment is not limited as long as the post-treatment agent is used in a state where the tannic acid of the pre-treatment agent is present in the hair. It may be used before, may be used between the pretreatment agent and the posttreatment agent, or may be used after the posttreatment agent.

  The multi-component hair treatment agent of this embodiment can be used as a hair care agent or the like. A “hair care agent” is a hair treatment agent used for the care and care of hair. Examples of hair care agents include treatments used after shampooing, treatments for pre-treatment of perms, treatments for post-treatment of perms, treatments for pre-treatment of coloring, treatments for post-treatment of coloring, Treatment for pre-treatment of bleach and treatment for post-treatment of bleach.

  EXAMPLES Hereinafter, although this invention is explained in full detail based on an Example, this invention is not interpreted limitedly based on description of this Example.

  A pretreatment agent and a posttreatment agent were produced, and the hair treatment of Examples and Comparative Examples was performed. The details are as follows.

(Pretreatment agent)
A 1% by mass aqueous solution of hydrolyzable tannin (“G Tannic Acid” manufactured by DSP Gokyo Food & Chemical Co., Ltd.) was produced as a pretreatment agent.

(Post-treatment agent)
Follows keratin derivative, a -S-S-CH ₂ -COOH or a salt thereof according to the reduction step and the oxidizing agent mixing process to produce a keratin derivative comprising a side group, the keratin derivative according to the solid-liquid separation step and the recovery step It collect | recovered and the solution of the hydrolysis keratin derivative provided with the said side chain group was manufactured by the process of the keratin derivative in a heating process.

Reduction step Merino wool, washed with a neutral detergent and dried, was cut to about 5 mm. 5 parts by weight of this wool, 15.4 parts by weight of a 30% by weight aqueous sodium thioglycolate solution and 8.5 parts by weight of a 6 mol / L aqueous sodium hydroxide solution are mixed, and water is further mixed to give a total amount of 150 parts by weight and a pH 11 coating. A treatment solution was prepared. This liquid to be treated was stirred at 45 ° C. for 1 hour. Subsequently, water was further mixed to make the total amount 200 parts by mass, left under conditions of 45 ° C. for 2 hours, and then naturally cooled until the liquid temperature reached room temperature.

Oxidant mixing step While stirring the liquid to be treated after the reduction step, 178 parts by mass of an aqueous solution containing 15.26 parts by mass of 35% by mass hydrogen peroxide was mixed with the liquid while stirring over about 30 minutes. (The pH of the liquid to be treated increased with the mixing of the hydrogen peroxide solution, but the pH range was adjusted to 10 or more and 11 or less by mixing an aqueous solution of about 20% by mass acetic acid.) Then, about 20 mass% acetic acid aqueous solution was mixed gradually, and it adjusted so that the pH of a to-be-processed liquid might become 11-7 gradually. Thus, a keratin derivative solution was obtained.

Solid-liquid separation step and recovery step By filtering the keratin derivative solution, insoluble matters in the solution were removed. Then, 160 mass parts of aqueous solution which mix | blended 97.2 mass parts of 36 mass% hydrochloric acid aqueous solution was added to the collect | recovered liquid part (filtrate). By this addition, the pH of the keratin derivative solution was changed from 7 to 4, thereby causing precipitation of the keratin derivative. This precipitate was recovered and washed with water to obtain a solid keratin derivative.

Heating Step An aqueous solution in which the solid keratin derivative obtained in the recovery step was 1% by mass and the pH was 8 with 2-amino-2-methyl-1-propanol was heated at 85 ° C. for 5 hours. The liquid was cooled to room temperature and then filtered to obtain an aqueous solution of a hydrolyzed keratin derivative.

The preparation of the post-treatment agent was 1% by mass of the hydrolyzed keratin derivative obtained in the heating step, 3% by mass of 1,3-butylene glycol, 1% by mass of phenoxyethanol, 3% by mass of lauryldimethylaminoacetic acid betaine and water (remainder). It was performed by blending. And in order to confirm the permeability of the hydrolyzed keratin derivative described later to the hair, FTSC-MES was added to the post-treatment agent, and unreacted FTSC was removed by a gel filtration column . The FTSC-MES has a pH of 5 by adding a 0.2M NaOH aqueous solution dropwise to a solution obtained by dissolving 1.065 parts by mass of 2- (N-Morpholino) ethansulfuric Acid (MES) in 40 parts by mass of water. Prepared by dissolving 0.00042 parts by mass of the fluorescent dye Fluorescein-5-thiosemicarbazide (FTSC) in MES aqueous solution and adding water to a total amount of about 50 parts by mass It is.

(Example)
A hair sample containing hair with a history of hair dyeing with an oxidative hair dye is collected from a Japanese woman, and this is subjected to washing with a commercially available shampoo, ethanol washing, washing with water and drying in order. It was prepared as a hair treatment target. In the hair treatment of Examples, the hair was immersed in the prepared pretreatment agent for 5 minutes, and then the FTSC-MES was added and then immersed in the treatment agent for 30 minutes. Thereafter, the hair was washed with water and dried.

(Comparative example)
The hair treatment was performed in the same manner as in Example except that the pretreatment agent was changed to water.

(Evaluation of permeability)
The hair tips of Examples and Comparative Examples were cut with a microtome, and the cut surface was observed with a fluorescence microscope (excitation light wavelength: 340 nm). FIG. 1 is a photographed image showing the result of observation of the cut surface of the example with a fluorescence microscope, and FIG. 2 is a photographed image showing the result of observation of the cut surface of the comparative example with a fluorescence microscope. As shown in FIG. 1 and FIG. 2, while in the captured image of the comparative example, uniform fluorescence can be confirmed over the entire cut surface (see FIG. 2), in the example, the fluorescence is weakened toward the center (FIG. 1). reference). That is, in the hair treatment of the example using the pretreatment agent, the penetration of the hydrolyzed keratin derivative into the hair was suppressed.

Claims (4)

A pretreatment agent containing tannic acid,
And a post-treatment agent containing hydrolyzed keratin or hydrolyzed keratin derivative.   The multi-component hair treatment agent according to claim 1, wherein hydrolyzable tannin is blended as tannic acid in the pretreatment agent. As the hydrolyzed keratin derivative in the post-treatment agent, one having one or more side chain groups having units selected from the structures represented by the following formulas (I) to (III) and salts of these structures: The multi-component hair treatment agent according to claim 1 or 2, which is blended.
_{-S-S- (CH 2) n} -COOH (I)
(In the formula (I), n is 1 or 2.)
_{-S-S-CH (CH 3} ) -COOH (II)
_{-S-S-CH (COOH)} -CH 2 -COOH (III) A pretreatment step of applying a pretreatment agent containing tannic acid to the hair;
After the pretreatment step, a posttreatment step of applying to the hair a posttreatment agent containing hydrolyzed keratin or hydrolyzed keratin derivative; and
A hair treatment method comprising: