JP6647783B2 - Information processing device and program - Google Patents

Description

  The present invention relates to a technique for determining a therapeutic agent used for treating an infectious disease.

  There are techniques for determining the therapeutic to use in the treatment of an infectious disease. For example, Patent Literature 1 discloses a technique for determining a priority index indicating that an antimicrobial should be preferentially selected for a pathogenic microorganism based on case data.

JP-A-2004-206555

According to the technique disclosed in Patent Document 1, when the name of a pathogenic bacterium, which is a microorganism causing an infectious disease, is specified, a therapeutic agent to be used for treating infectious disease is determined based on the priority index described above. Therapeutic agents effective against bacilli can be administered. However, after the patient is first diagnosed and before the name of the causative bacterium is identified, it is necessary, for example, to culture and increase the microorganisms collected from the patient before testing, usually one day or more. It takes a period of time. Nevertheless, if nothing is done during this period, the patient's condition may be deteriorated, so that a treatment that is likely to be effective is administered as much as possible to prevent the condition from being deteriorated.
Therefore, an object of the present invention is to make it possible to use a therapeutic agent which can obtain an effect with a higher probability for the treatment of infectious diseases even if the microorganism causing the infectious disease is not specified.

The present invention provides an acquiring means for acquiring a list of therapeutic agents for infectious diseases used in a medical facility, and a microorganism collected from a patient who is treated for infectious diseases in the medical facility, is classified into a first taxonomic category. If it is presumed to belong, the list is obtained from the patient from the list obtained by the obtaining means based on the first results previously tested for the efficacy of the therapeutic agent on the microorganisms belonging to the first category. Selection means for selecting a therapeutic drug expected to have an effect on microorganisms, which corresponds to a therapeutic drug for infectious disease and a category of the same class as the first category of microorganisms having no resistance gene to the therapeutic drug. with the, information obtained as a result of inspecting the gene of the microorganism, out to output a selection means for use as the first result, the information representative of the therapeutic agent which is selected by said selection means An information processing apparatus and means.

Further, the information corresponding to the classification of microorganisms having no resistance gene is information created based on information provided from a database that collects the results of tests for each therapeutic drug performed at a plurality of medical facilities. it may be.

The present invention provides a computer, an acquiring means for acquiring a list of therapeutic agents for infectious diseases used in a medical facility, and a microorganism collected from a patient who is treated for infectious diseases in the medical facility, the taxonomical data. When it is estimated that the patient belongs to one category, the patient obtains the list from the list acquired by the acquisition unit based on the first result previously tested for the effect of the therapeutic agent on the microorganism belonging to the first category. Selection means for selecting a therapeutic agent expected to be effective against the collected microorganisms, wherein the therapeutic agent for infectious disease and microorganisms having no resistance gene to the therapeutic agent have the same class as the first category. preparative associated, the information obtained as a result of inspecting the gene of the microorganism, and selecting means used as the first result represents a therapeutic agent selected by said selection means It provides a program for causing the functions as an output means for outputting a broadcast.

  ADVANTAGE OF THE INVENTION According to this invention, even if the microorganism which causes an infectious disease is not specified, the therapeutic agent which can obtain an effect with a higher probability can be used for treatment of infectious disease.

The figure showing the whole structure of the medical information system concerning embodiment. Diagram showing hardware configuration of server device Diagram showing hardware configuration of user device Diagram showing functional configuration realized in medical information system Diagram showing an example of an image for requesting reference information FIG. 7 is a diagram illustrating an example of a first result of a past test on the efficacy of a therapeutic agent. The figure showing an example of the information showing the displayed therapeutic agent Diagram showing an example of displayed supplementary information The figure showing an example of the procedure of operation | movement of each apparatus until the list of therapeutic agents is acquired. Diagram showing an example of the procedure of the operation of each device until the reference information is displayed Diagram showing an example of information provided by ARDB Diagram showing an example of a resistance gene table Diagram showing an example of a resistance gene table

[1] Embodiment [1-1] Overall Configuration, etc. FIG. 1 shows an overall configuration of a medical information system 1 according to an embodiment. The medical information system 1 is a system for providing medical information to medical staff such as doctors and nurses who are users of the system. In the present embodiment, the medical information system 1 provides the user with information (hereinafter referred to as “reference information”) that is used as a reference when determining a therapeutic agent to be used for treating an infectious disease.

  The medical information system 1 includes a network 2, a server device 10, and a user device 20. The network 2 is a system that mediates data exchange between devices, and is, for example, a LAN (Local Area Network) provided in a medical facility. A server device 10 and a user device 20 are connected to the network 2. The user device 20 is an information processing device that accepts input of information by a user and displays information provided from the server device 10, and functions as an interface when the user uses medical information. The server device 10 is an information processing device that processes information transmitted from the user device 20, and is a device that provides the processed information to the user via the user device as medical information. The server device 10 provides the above-mentioned reference information to the user as one of the medical information.

  FIG. 2 illustrates a hardware configuration of the server device 10. The server device 10 is a computer including a control unit 11, a storage unit 12, and a communication unit 13. The control unit 11 includes a CPU (Central Processing Unit), a ROM (Read Only Memory), a RAM (Random Access Memory), and a real-time clock. The CPU controls the operations of the storage unit 12 and the communication unit 13 by executing a program stored in the ROM or the storage unit 12 using the RAM as a work area. The real-time clock has a classification function for calculating the current date and time. The storage unit 12 includes a hard disk or the like, and stores data, programs, and the like used by the control unit 11 for control. The communication unit 13 includes a communication circuit for performing communication via the network 2, and transmits and receives data via the network 2.

  FIG. 3 shows a hardware configuration of the user device 20. The user device 20 is a computer including a control unit 21, a storage unit 22, a communication unit 23, a display unit 24, and an operation unit 25. The control unit 21 is the same type of hardware as the control unit 11. The storage unit 22 is the same type of hardware as the storage unit 12, and the communication unit 23 is the same type of hardware as the communication unit 13. The display unit 24 has, for example, a liquid crystal display, and displays an image on a display surface based on control performed by the control unit 21. The operation unit 25 includes operation devices such as a keyboard and a mouse, and supplies operation data representing the contents of the operation to the control unit 21 in response to a user operation.

[1-2] Functional Configuration A program for realizing a function of providing medical information to a user is stored in each storage unit of the server device 10 and the user device 20, and by executing this program, Are implemented.
FIG. 4 shows a functional configuration realized in the medical information system 1. The server device 10 includes an acquisition unit 101, a selection unit 102, and an output unit 103, and the user device 20 includes a transmission unit 201, a request unit 202, and a display unit 203.

  The transmitting unit 201 is a unit that transmits a list of therapeutic agents for infectious diseases used in the medical facility to the server device 10. The medical facilities referred to here include general facilities such as hospitals and clinics where administration of therapeutic agents to patients with infectious diseases is performed. Infectious diseases are diseases caused by pathogenic microorganisms such as bacteria and viruses. In the present embodiment, the medical information system 1 is introduced in the hospital A, and the list of antibacterial drugs (medicines used for the treatment of infectious diseases caused by bacteria) used in the medical facility of the hospital A is the treatment of infectious diseases. Treated as a list of drugs.

  For example, even if the same kind of antibacterial drug such as a penicillin-based antibacterial drug is used, the effect is not always the same if the companies that manufacture it are different. However, because it is difficult to keep antibiotics available for all companies, many healthcare facilities use antibiotics manufactured by a specific company to maintain a list of antibiotics. If this antimicrobial list is managed, for example, in a paper ledger, the user inputs the name of the antimicrobial included in the list to the user device 20. The transmitting unit 201 transmits a list of antibacterial agents having the names thus input to the server device 10.

  If the list of antimicrobial agents is stored in another device included in the medical information system 1, the transmitting unit 201 requests the list of antimicrobial agents from the device and sends the transmitted list to the server. The data may be transferred to the device 10. When the list of antibacterial agents is updated, the transmission unit 201 transmits the list of antibacterial agents to the server device 10 each time. In this case, the transmitting unit 201 may transmit only the updated list. The list of antimicrobial agents received by the server device 10 is supplied to the acquisition unit 101.

  The acquiring unit 101 is a unit for acquiring a list of therapeutic agents for infectious diseases described above. In the present embodiment, the acquisition unit 101 acquires the list of antimicrobial agents transmitted from the transmission unit 201 to the own device and the list of therapeutic agents for infectious diseases, as described above. Note that the acquisition unit 101 may acquire the list of antibacterial drugs by another method. For example, the list may be sent from a device that manages the list of antibacterial drugs periodically or whenever the list is updated. A list of antimicrobial agents may be obtained. The acquisition unit 101 supplies the acquired antimicrobial agent list to the selection unit 102.

  The request unit 202 is a unit that requests the above-mentioned reference information (information that is used when determining a therapeutic agent to be used for treating an infectious disease) based on a user operation. This request can be made even if the microorganism of the pathogen that caused the infection has not been identified. The fact that the microorganism is specified means that the taxonomic classification of the microorganism is specified up to the “species” which is the lowest class. In order to specify the species of the microorganism, it is necessary to culture and increase the microorganism before conducting the test. It takes a period of one day or more after the collection of the microorganism until the result is obtained. The user of the medical information system 1 performs an operation of requesting the user device 20 for reference information for determining a therapeutic drug in order to perform treatment on the patient during this period.

  The request for the reference information is based on the premise that the “genus” (a class of one rank higher than “species”) of microorganisms collected from a patient has been estimated. The genus is estimated by, for example, observing an image of a gram-stained bacterium using a microscope by a medical worker. At this stage, it is not possible to identify the genus of the microorganism, but it is possible to get a rough estimate. Since the time required for estimating the genus by Gram staining is about 30 minutes, the operation for requesting the reference information can be performed in less than one hour as soon as the diagnosis of the patient is started. The request unit 202 displays an image for the user to perform this operation on the display unit 24 as the display unit.

  FIG. 5 shows an example of an image for requesting reference information. In this example, a display section A1 for displaying the estimated genus and an operator B1 for deciding to request the reference information are displayed on the display section 24. The user inputs the estimated genus into the display column A1 or selects from the pull-down list A2 of the genus shown in the figure. After that, when the user performs an operation on the operation element B1, the requesting unit 202 outputs a message to the patient with an infection caused by a bacterium belonging to the genus (in this example, Staphylococcus: staphylococcus) displayed in the display column A1. Request data indicating that reference information for determining a therapeutic agent to be used for treatment is transmitted to the server device 10. The request data received by the server device 10 is supplied to the selection unit 102.

  The selection unit 102 is a unit that selects a therapeutic agent that is expected to have an effect on the microorganisms collected from the patient from among the therapeutic agents included in the use list acquired by the acquiring unit 101. The selection of the therapeutic agent by the selecting means 102 may be one or two or more. In any case, for example, a doctor who is a user is used to determine a therapeutic agent to be actually used for treating an infectious disease from the selected therapeutic agent. That is, the selection unit 102 selects a candidate for a therapeutic agent to be actually used for treating an infectious disease.

  More specifically, when the microorganisms collected from a patient who is treated for an infectious disease at a medical facility are presumed to belong to the taxonomic first category, the selecting means 102 performs the treatment on the microorganisms belonging to the first category. The selection is made based on the results of a past test on the efficacy of the drug (hereinafter referred to as “first results”). In this embodiment, the genus (Staphylococcus in the example of FIG. 5) input or selected by the user in the example of FIG. 5 is used as the first category of the estimated microorganism. The first result will be described with reference to FIG.

  FIG. 6 shows an example of the first result obtained in the past inspection. In this example, the susceptibility rate (unit:%) of each Staphylococcus tested at Hospital A for each antibacterial drug is represented by a bar graph. Such a graph is called an antibiogram. In the antibiogram shown in FIG. 6, the name of each antibacterial drug is represented by a generic name such as ABCC (Ampicillin). For example, when a plurality of companies manufacture the antibacterial drug with the generic name Shows the results of tests performed with antimicrobial agents of a company that has a transaction at Hospital A.

  In different medical facilities, different companies may produce different antimicrobial agents, or patients may have different germs of the same genus but different species. is there. Therefore, the antibiogram differs for each medical facility, and is generally created for each medical facility. The antibiogram shown in FIG. 6 represents the result of a test that tests the effect of a therapeutic agent on microorganisms collected from a patient previously treated at Hospital A.

  Some antimicrobials, including, for example, ABPC, have a susceptibility of 0%. This indicates that tests performed at Hospital A showed that these antibiotics had no effect on Staphylococcus in all tests. In the case of an antimicrobial with a sensitivity of 100%, such as ABK (Arbekacin: arbekacin), the efficacy appears in all tests. This indicates that the effect has appeared. Therefore, antimicrobial drugs with higher susceptibility are expected to be more effective. In Hospital A, the susceptibility of ABK, VCM (Vancomycin: vancomycin), TEIC (Teicoplanin: teicoplanin), and LZD (Linezolid: linezolid) was 100%. Four antimicrobial agents are expected to be the most effective.

  In the storage unit 12 of the server device 10, in addition to the antibiogram shown in FIG. 6, data representing an antibiogram of another genus is stored. The selection means 102 refers to the antibiogram data indicating the result of the test for the bacterium of the estimated genus indicated by the request data transmitted from the user device 20, and determines the antimicrobial agent having the highest susceptibility (that is, If there is more than one, the plurality of antibiotics) are selected as therapeutic agents that are expected to be effective against microorganisms collected from the patient. As described above, in the present embodiment, the selection unit 102 performs the test for testing the effect of the therapeutic agent on the microorganisms collected from the patient previously treated at the medical facility (hospital A in this example) where the patient is to be treated. The result is used as the first result described above. The selection unit 102 supplies information representing the selected therapeutic agent to the output unit 103.

  The output unit 103 is a unit that outputs information indicating the therapeutic agent selected by the selection unit 102. In the present embodiment, the output unit 103 outputs the information representing the therapeutic agent supplied from the selection unit 102 to the user device 20 to which the request data has been transmitted. The output unit 103 outputs, in addition to the information indicating the selected therapeutic agent, information indicating the organ transferability, excretion route, administration method, contraindications, and side effects of the therapeutic agent as supplementary information of the therapeutic agent.

  Organ transferability is information indicating the degree to which the administered therapeutic agent migrates (reaches) to organs such as the kidney and liver, and the excretion route passes when the administered therapeutic agent is excreted This is information indicating a route (mainly, kidney and liver). The administration method is information indicating a method of administering the therapeutic agent (oral administration, intravenous injection, sublingual administration, etc.), and the contraindications are information indicating a patient who should not administer the therapeutic agent. In addition, the side effect is information indicating an effect that is not useful for treating a disease. The storage unit 12 of the server device 10 stores such additional information in association with, for example, the name of a therapeutic agent. When outputting the information indicating the therapeutic agent, the output unit 103 reads the incidental information stored in association with the name of the therapeutic agent and outputs the information together with the information indicating the therapeutic agent.

  The display means 203 displays the information representing the therapeutic agent and the accompanying information output by the output means 103 as reference information requested by the requesting means 202 (information that is used as reference when determining a therapeutic agent to be used for treatment of an infectious disease patient). ). Upon receiving both information output from the output unit 103, the display unit 203 displays the received information using the display unit 24, which is a display unit of its own device.

  FIG. 7 shows an example of information indicating the displayed therapeutic agent. In this example, the display means 203 displays on the display unit 24 a display column A11 for displaying “Staphylococcus” which is the genus entered or selected in the example of FIG. 5, and it is expected that the bacteria of this genus have an effect. Display columns A21, A22, A23, and A24 displaying the antimicrobial agents (ABK, VCM, TEIC, LZD in this example). The display unit 203 displays operators B21, B22, B23, and B24 for displaying additional information, arranged in each display column. When these operators are operated, the display unit 203 displays the supplementary information of the therapeutic agent displayed side by side with the operated operators.

  FIG. 8 shows an example of the displayed supplementary information. In this example, the display means 203 displays the name of the antibacterial drug “XXX” in the display field A31, and displays incidental information (organ transferability, excretion route, administration method, contraindications, and side effects) of the antibacterial drug in the display field A31. , A32, A33, A34 and A35. These display columns also serve as operators, and when each display column is operated, the display means 203 displays detailed information of the incidental information displayed in the display column.

  When the user operates the operation element B1 described with reference to FIG. 5 to request the reference information, the reference information as shown in FIGS. 7 and 8 is displayed as described above. Since these pieces of reference information are displayed based on the estimated genus, it is possible to display the information even before the species of the microorganism is identified by the inspection. A doctor who is a user of the medical information system 1 refers to this reference information and determines, for example, one of the antibacterial drug candidates shown in FIG. 7 as a therapeutic drug to be used for treating a patient with an infectious disease. Administered to the patient. The antimicrobial agent administered in this way is a therapeutic agent that has proven effective with a high probability in the past in tests for bacteria belonging to the estimated genus, and if it is against bacteria belonging to the same genus, other The effect is likely to appear as compared with the remedy. As described above, according to the present embodiment, even if the microorganism causing the infectious disease has not been identified, a higher probability than the case where the selection of the therapeutic agent based on the first result is not performed is performed. Can be used for the treatment of infectious diseases.

  In addition, when information indicating a plurality of therapeutic agents is displayed as in the example of FIG. 7, by comparing the accompanying information, for example, a treatment that has higher organ transferability and has a higher effective effect when administered to a patient. The drug can be used to treat an infection. In addition, it is possible to prevent a therapeutic agent from being administered to a patient having a disease in the excretion route (mainly, kidney or liver), or to use an incorrect administration method. In addition, it is possible to prevent the administration of a therapeutic drug to a patient who is a contraindicated subject or the administration of a therapeutic drug having a large side effect.

  Further, in the present embodiment, the candidate of the therapeutic agent is selected using the antibiogram as the first result. Antibiograms are results of previous testing at a healthcare facility that treats a patient, for example, using results previously tested at another healthcare facility that uses a drug manufactured by a different company than that medical facility Therapeutic agents that are more likely to be effective than may be used to treat an infection.

[1-3] Operation The medical information system 1 performs a providing process for providing reference information to a user based on the above configuration. Hereinafter, a procedure of an operation performed by each device included in the medical information system 1 in the providing process will be described with reference to FIGS. 9 and 10.

  FIG. 9 shows an example of a procedure of operation of each device until a list of therapeutic agents is obtained. This procedure is started when, for example, the user operates the user device 20 to display an image for inputting the name of a therapeutic agent included in the therapeutic agent list. When this procedure is started, first, the user device 20 accepts the input of the name of the therapeutic agent by the user (step S11). Next, when the user device 20 transmits a list including the name of the inputted therapeutic agent, that is, a list of therapeutic agents to the server device 10 (step S12), the server device 10 acquires the transmitted therapeutic agent list. (Step S13). The operations of steps S11 and S12 are performed by the transmitting unit 201, and the operations of step S13 are performed by the obtaining unit 101. Thus, the list of therapeutic agents is obtained by the server device 10.

  FIG. 10 shows an example of the operation procedure of each device until the reference information is displayed. This procedure is performed, for example, by assuming that a medical worker as a user estimates that a microorganism collected from a patient belongs to the first taxonomic category (the genus “Staphylococcus” in the above example), The operation starts when the image shown in FIG. 5 is displayed by operating. When this procedure is started, first, the user device 20 receives an input of the estimated first category (step S21). Next, the user device 20 receives an operation for requesting reference information to be used when determining a therapeutic agent to be used for treatment of a patient from whom a microorganism presumed to belong to the first category is collected (step S22), The request data indicating the request is transmitted to the server device 10 (Step S23). The operations of steps S21, S22, and S23 are performed by the request unit 202.

  When the server device 10 receives the request data in step S23, based on the first section indicated by the request data and the antibiogram described in FIG. 6, the server device 10 retrieves the patient from the list of therapeutic agents acquired in step S13 in FIG. A therapeutic agent that is expected to have an effect on the microorganisms collected from is selected (step S24). Subsequently, the server device 10 outputs information indicating the selected therapeutic agent to the user device 20 (step S25), and the user device 20 outputs the output information, that is, the information indicating the selected therapeutic agent. It is displayed (step S26). The operation of step S24 is performed by the selection unit 102, and the operation of step S25 is performed by the output unit 103. The operation of step S26 is performed by the display unit 203.

[2] Modifications The embodiment described above is merely an example of the embodiment of the present invention, and may be modified as follows. In addition, the above-described embodiments and the modifications described below may be implemented in combination as needed.

[2-1] First Result The first result used by the selection unit 102 is not limited to the one described in the embodiment. The selection means 102 uses, for example, information associating a therapeutic drug for an infectious disease with a category of the same class as the first category of microorganisms having a resistance gene to the therapeutic drug. The first result is information obtained as a result of examining the gene of the microorganism. ARDB (Antibiotic Resistance Genes Database) is known as a database that collects such information for each antibacterial drug obtained as a result of tests performed in medical facilities around the world. The ARDB is open to the public on the Internet or the like, and when an antibacterial drug is designated, information on the genus and species of a bacterium having a resistance gene to the antibacterial drug is provided.

  FIG. 11 shows an example of information provided by the ARDB. In this example, “benzylpenicillin” is designated as an antibacterial agent, and the genus of bacteria having a resistance gene to this antibacterial agent is listed. The storage unit 12 of the server device 10 stores whether or not the bacterium belonging to each genus is an antibacterial agent having no resistance gene, which is created based on the information provided in this way, in other words, belongs to each genus. A table (hereinafter referred to as a “resistance gene table”) is stored for each antibacterial agent, indicating whether the antibacterial agent is effective against the bacteria.

  FIG. 12 shows an example of the resistance gene table. In this example, an antimicrobial agent without a resistance gene is indicated by “○”, and an antimicrobial agent with a resistance gene is indicated by “×”. For example, as for the genus “Shigella” (Shigella), the bacterium belonging to this genus does not have a resistance gene for the antibacterial agents α and γ that are marked “O”, and is marked “X”. It has been shown to have resistance genes to certain antimicrobial agents β and Δ. In other words, in the case of bacteria belonging to this genus, the antibacterial agents α and γ are likely to be effective regardless of the bacterial species, and the antibacterial agents β and Δ have no effect or are effective depending on the bacterial species. However, the effect is likely to be small. Therefore, if the genus indicated by the request data transmitted from the requesting means 202 is “Shigella”, the selecting means 102 expects that the antibacterial agents α and γ have an effect on the microorganisms collected from the patient. Be selected as a treatment.

  The antibiogram described in the embodiment may not be created in a small-scale medical facility, and even in a medical facility that creates this, if the genus of a microorganism that has not been tested in the past is estimated. Will have no antibiogram. On the other hand, the test for the resistance gene described in the present modified example is performed in medical facilities around the world, and the mechanism for sharing the results is in place, so that the antibiogram cannot be used as described above. Even in this case, the selection of the therapeutic agent using the first result can be performed.

[2-2] Specified Category In the treatment of infectious diseases, as described in the embodiment, after estimating the "genus" of a microorganism, the "species" of the microorganism is specified. The selecting means 102 selects a therapeutic agent based on the estimated first category (in the embodiment, the genus) and, in addition, selects the therapeutic agent based on the specified category (hereinafter, referred to as “second category”; for example, a bacterial species). To select a therapeutic agent. This selection is based on the fact that the microorganisms presumed to be the first category are identified as belonging to the second category of the lower class than the first category, and have been previously tested for the efficacy of the therapeutic agent on the microorganisms belonging to the second category. This is performed when a result (hereinafter referred to as “second result”) is obtained.

As the second result, for example, a table in which the resistance gene table described in the above modified example is represented for each bacterial species is used.
FIG. 13 shows an example of the resistance gene table of the present modification. In this example, the presence or absence of a resistance gene to each antibacterial drug of four strains of the genus “Shigella”, “dysenteriae”, “flexneri”, “boydii” and “sonnei”, is shown. For example, if the strain is "flexneri", the antimicrobial agents α, β, and γ that are marked with “○” are likely to be effective. ", Antimicrobial agents α, γ and Δ are highly likely to be effective.

  The selection means 102 selects a therapeutic drug using, for example, the resistance gene table shown in FIG. Specifically, the selection means 102 determines the second result, that is, the therapeutic agent for the microorganisms belonging to the second category, when the microorganisms collected from the patient to be treated for the infectious disease are identified as belonging to the second category. Based on the results of the past examination of the effect of the microorganism, a therapeutic agent that is expected to have an effect on the microorganism is selected from the list acquired by the acquiring unit 101. As a result, in the case where up to the second category of microorganisms is specified, a therapeutic agent that can obtain an effect with a higher probability than in the case where the therapeutic agent is not selected based on the above-described second result is used for infectious diseases. It can be used for treatment.

[2-3] First Class and Second Class In the embodiment and the modified examples described above, the first class in taxonomical terms is "fungi" and the second class is "fungal species", but is not limited thereto. . For example, if the pathogen of the infectious disease is a virus, the first category is “genus of virus” and the second category is “virus species”. In addition, “family” or “eyes” which are higher ranks than “genus” may be used as the first division. In this case, the second section may be a class of a lower rank than the first section, for example, the first section is "family" and the second section is "genus".

[2-4] Selection means The selection means 102 may select a therapeutic agent by a method different from the method described above. For example, when the priority is determined for each therapeutic agent and the upper limit of the number of therapeutic agents to be selected is determined, the selecting unit 102 determines that there is an effect on microorganisms collected from the patient. For example, among the expected therapeutic agents, the number of therapeutic agents from the highest priority to the upper limit is selected. In this case, for example, when there is a therapeutic agent that has a good track record in the medical facility, is reliable, and is to be preferentially used, the therapeutic agent can be easily selected.

[2-5] Output Means In the embodiment, the output means 103 outputs information representing the therapeutic agent as a character string and incidental information represented as a character string. However, the present invention is not limited to this. Information represented by voice, or supplementary information represented by an image or voice may be output. Further, the output unit 103 may not output the additional information, or may output only a part of the additional information.

  The output destination of the information of the output unit 103 is not limited to the user device 20 described in the embodiment. For example, when a display unit is connected to the server device 10, the output unit 103 may output information to the display unit and display the information. Further, the output unit 103 may output information to a destination corresponding to the user, such as the user's e-mail address or SNS (Social Networking Service) account. In short, the output unit 103 may output information to any output destination as long as the user can confirm the output information.

[2-6] Category of the Invention The present invention can be regarded as other devices that realize the respective units shown in FIG. In addition, it can be considered as a system such as a medical information system including these devices. Further, the present invention can be regarded as an information processing method for realizing the processing performed by those devices, and also as a program for causing a computer that controls those devices to function. This program may be provided in the form of a recording medium such as an optical disk in which the program is stored, or provided in a form in which the program is downloaded to a computer via a network such as the Internet and installed and made available. May be done.

DESCRIPTION OF SYMBOLS 1 ... Medical information system, 2 ... Network, 10 ... Server device, 20 ... User device, 11, 21 ... Control part, 12, 22 ... Storage part, 13, 23 ... Communication part, 24 ... Display part, 25 ... Operation part .., 101: acquisition means, 102: selection means, 103: output means, 201: transmission means, 202: request means, 203: display means

Claims (3)

Obtaining means for obtaining a list of treatments for infectious diseases used in the medical facility;
If the microorganisms collected from a patient undergoing treatment for an infectious disease at the medical facility are presumed to belong to the taxonomic first category, they have been previously tested for the efficacy of the therapeutic agent on the microorganisms belonging to the first category. was based on the first results, from the list acquired by the acquisition means, a selection means for selecting expected therapeutic agent to be efficacious against microorganisms taken from the patient, the therapy of infectious diseases Selection using information obtained as a result of examining the gene of the microorganism, associating a drug with the first class of the microorganism having no resistance gene to the therapeutic drug and the same class as the first result. Means ,
An output unit that outputs information representing the therapeutic agent selected by the selection unit. The information in which the classification of the microorganisms not having the resistance gene is associated is information created based on information provided from a database in which results of tests for each therapeutic drug performed in a plurality of medical facilities are collected.
The information processing device according to claim 1. Computer
Means for obtaining a list of treatments for infectious diseases used in the medical facility;
If microorganisms collected from a patient undergoing treatment for an infectious disease at the medical facility are presumed to belong to the first taxonomic category, they were previously tested for the efficacy of the therapeutic agent on the microorganisms belonging to the first category. was based on the first results, from the list acquired by the acquisition means, a selection means for selecting expected therapeutic agent to be efficacious against microorganisms taken from the patient, the therapy of infectious diseases Selection using information obtained as a result of examining the gene of the microorganism, associating a drug with the first class of the microorganism having no resistance gene to the therapeutic drug and the same class as the first result. Means ,
A program for functioning as output means for outputting information representing the therapeutic agent selected by the selection means.

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