JP6686902B2 - Cosmetic composition containing acyl basic amino acid derivative and basic amino acid - Google Patents

Description

  The present invention contains at least one component selected from the group consisting of (A): acyl basic amino acid derivative, and (B): basic amino acid and its salt, and acyl basic amino acid lower ester and its salt. , For example for compositions used as cosmetics.

  The following formula:

(In the formula, R ^a and R ^b are a hydrogen atom or an alkyl group, and n is an integer of 0 to 12.)
The compound represented by or a salt thereof (hereinafter, also referred to as “lauroyl amino acid derivative”) is expected to exhibit a moisturizing effect (moisturizing feeling) in addition to improving familiarity to the skin when blended into cosmetics ( Patent Document 1, Non-Patent Document 1, Non-Patent Document 2, etc.). Therefore, studies are being made to incorporate lauroyl amino acid derivatives into cosmetics.

  However, when the lauroyl amino acid derivative is blended with a liquid cosmetic such as a lotion or an emulsion, due to the gelling ability of the lauroyl amino acid derivative (Patent Document 1), it gels with time even at a low concentration and the fluidity of the liquid cosmetic decreases. And the stability is poor. In addition, since the lauroyl amino acid derivative exhibits spinnability, it is not easy to use and may have a peculiar squeaky feeling during semi-wet.

JP, 2004-323505, A

Org. Biomol. Chem., 2003, 1, 4124-4131 New J. Chem., 2005, 29, 1439-1444

  An object of the present invention is to have a good feeling of use without squeaky feeling, without impairing the familiarity and moisturizing feeling to the skin of the acyl basic amino acid derivative typified by lauroyl amino acid derivative, and stability with time and heat. An object of the present invention is to provide a composition having excellent stability and good usability without spinnability.

  The present inventors have conducted extensive studies to achieve the above object, and as a result, Component (A): a compound represented by the following formula (1) (hereinafter, also referred to as “compound (1)”) or a salt thereof, (B): A composition containing at least one component selected from the group consisting of a basic amino acid and a salt thereof, and an acyl basic amino acid lower ester and a salt thereof has a good feeling of use without squeaky feeling. The inventors have found that they have excellent aging stability and thermal stability, and have good usability without spinnability, and have completed the present invention.

That is, the present invention is as follows.
[1] Component (A): Formula (1)

(In the formula,
R ¹ and R ² are each independently an alkyl group having 5 to 21 carbon atoms or an alkenyl group having 5 to 21 carbon atoms,
R ³ and R ⁴ are each independently a hydrogen atom, an alkyl group having 1 to 22 carbon atoms or an alkenyl group having 2 to 22 carbon atoms,
z is an integer of 0 or more,
x and y are each independently an integer of 2 to 4. ) Or a salt thereof;
And component (B): a composition containing a basic amino acid and a salt thereof, and at least one component selected from the group consisting of an acyl basic amino acid lower ester and a salt thereof.
[2] The composition according to [1], wherein the component (A) is a compound in which z is an integer of 0 to 10 in the formula (1) or a salt thereof.
[3] The composition according to [1] or [2], wherein the component (A) is a compound in which z is 7 or 8 in the formula (1) or a salt thereof.
[4] The composition according to any one of [1] to [3], wherein the component (A) is a compound in which x and y are both 4 in the formula (1) or a salt thereof.
[5] The component (A) is a compound or a salt thereof in which R ¹ and R ² are each independently a linear alkyl group having 8 to 15 carbon atoms in the formula (1), [1] to The composition according to any one of [4].
[6] The composition according to any one of [1] to [5], wherein the component (A) is a compound or a salt thereof in which R ³ and R ⁴ are both hydrogen atoms in the formula (1).
[7] In the component (A), in the formula (1), R ¹ and R ² are each independently a linear alkyl group having 8 to 15 carbon atoms, and R ³ and R ⁴ are both hydrogen. The composition according to any one of [1] to [5], which is an atom, z is an integer of 0 to 10, and x and y are both 4 or a salt thereof.
[8] In the component (A), in the formula (1), R ¹ and R ² are both linear alkyl groups having 8 to 15 carbon atoms, and R ³ and R ⁴ are both hydrogen atoms, The composition according to any one of [1] to [5], wherein z is 7 or 8, and x and y are both 4 or a salt thereof.
[9] The composition according to any one of [1] to [5], wherein the component (A) is bis (N ^ε -lauroyl-L-lysine) sebacoilamide or a salt thereof.
[10] Component (A) is bis - - (octanoyl -L- lysine N ^epsilon), or a salt thereof selected from Sebacoyl amide, (N ^epsilon lauroyl -L- lysine) sebacoyl amide, and bis The composition according to any one of [1] to [5].
[11] The composition according to any one of [1] to [10], wherein the component (B) is arginine, lysine or histidine.
[12] The composition according to any one of [1] to [10], wherein the component (B) is cocoyl arginine ethyl ester pyrrolidone carboxylate or lauroyl arginine ethyl ester hydrochloride.
[13] The composition according to any one of [1] to [12], which contains the component (A) in an amount of 0.005 to 20% by weight based on the total amount of the composition.
[14] The composition according to any one of [1] to [13], which contains the component (B) in an amount of 0.005 to 20% by weight based on the total amount of the composition.
[15] A cosmetic containing the composition according to any one of [1] to [14].

  According to the present invention, it is possible to provide a composition having a good usability without squeaky feeling, excellent stability over time and thermal stability, and good usability without spinnability.

  The composition of the present invention comprises component (A): formula (1)

(In the formula,
R ¹ and R ² are each independently an alkyl group having 5 to 21 carbon atoms or an alkenyl group having 5 to 21 carbon atoms,
R ³ and R ⁴ are each independently a hydrogen atom, an alkyl group having 1 to 22 carbon atoms or an alkenyl group having 2 to 22 carbon atoms,
z is an integer of 0 or more,
x and y are each independently an integer of 2 to 4. ) Or a salt thereof,
And component (B): a composition containing at least one component selected from the group consisting of basic amino acids and salts thereof, and acyl basic amino acid lower esters and salts thereof.

  Hereinafter, embodiments of the present invention will be described in detail.

1. Component (A): The compound represented by formula (1) (compound (1)) or a salt thereof R ¹ and R ² are each independently an alkyl group having 5 to 21 carbon atoms or 5 to 21 carbon atoms. Is an alkenyl group.
The alkyl group having 5 to 21 carbon atoms means a linear or branched alkyl group having 5 to 21 carbon atoms, and specifically, a pentyl group, an isopentyl group, a neopentyl group, a hexyl group, an isohexyl group. , Neohexyl group, heptyl group, isoheptyl group, neoheptyl group, octyl group, isooctyl group, nonyl group, isononyl group, decyl group, isodecyl group, undecyl group, dodecyl group, tridecyl group, tetradecyl group, pentadecyl group, hexadecyl group, heptadecyl group Group, octadecyl group, nonadecyl group, icosyl group and the like.
The alkenyl group having 5 to 21 carbon atoms means a linear or branched alkenyl group having 5 to 21 carbon atoms, and specifically, a pentenyl group, a hexenyl group, a heptenyl group, an octenyl group, a nonenyl group. , Decenyl group, undecenyl group, dodecenyl group, tridecenyl group, tetradecenyl group, pentadecenyl group, hexadecenyl group, heptadecenyl group, octadecenyl group, nonadecenyl group, icosenyl group and the like.
The alkyl group having 8 to 15 carbon atoms means a straight-chain or branched alkyl group having 8 to 15 carbon atoms, specifically, octyl group, nonyl group, decyl group, undecyl group, dodecyl group. , Tridecyl group, tetradecyl group, pentadecyl group and the like.
The alkyl group having 8 to 11 carbon atoms means a linear or branched alkyl group having 8 to 11 carbon atoms, and specific examples thereof include an octyl group, a nonyl group, a decyl group, and an undecyl group. To be
R ¹ and R ² are preferably each independently an alkyl group having 8 to 15 carbon atoms, and more preferably each independently being an alkyl group having 8 to 11 carbon atoms.
In addition, R ¹ and R ² are preferably linear alkyl groups. Furthermore, it is preferable that R ¹ and R ² are the same.

R ³ and R ⁴ are each independently a hydrogen atom, an alkyl group having 1 to 22 carbon atoms or an alkenyl group having 2 to 22 carbon atoms.
The alkyl group having 1 to 22 carbon atoms means a linear or branched alkyl group having 1 to 22 carbon atoms, specifically, a methyl group, an ethyl group, a propyl group, an isopropyl group, a butyl group. , Isobutyl group, sec-butyl group, tert-butyl group, pentyl group, isopentyl group, neopentyl group, hexyl group, isohexyl group, neohexyl group, heptyl group, isoheptyl group, neoheptyl group, octyl group, isooctyl group, nonyl group, Examples thereof include isononyl group, decyl group, isodecyl group, undecyl group, dodecyl group, tridecyl group, tetradecyl group, pentadecyl group, hexadecyl group, heptadecyl group, octadecyl group, nonadecyl group and icosyl group.
The alkenyl group having 2 to 22 carbon atoms means a linear or branched alkenyl group having 2 to 22 carbon atoms, and specifically, an ethenyl group, a 1-propenyl group, a 2-propenyl group, 1 -Butenyl group, 2-butenyl group, 3-butenyl group, pentenyl group, hexenyl group, heptenyl group, octenyl group, nonenyl group, decenyl group, undecenyl group, dodecenyl group, tridecenyl group, tetradecenyl group, pentadecenyl group, hexadecenyl group, Examples thereof include a heptadecenyl group, an octadecenyl group, a nonadecenyl group and an icosenyl group.
R ³ and R ⁴ are preferably both hydrogen atoms.

z is an integer of 0 or more.
z is preferably an integer of 0 to 10, and more preferably 7 or 8.

x and y are each independently an integer of 2 to 4.
x and y are preferably both 4.

As the compound represented by the formula (1), the following compounds are preferable.
(Compound A)
R ¹ and R ² are each independently a linear alkyl group having 8 to 15 carbon atoms,
R ³ and R ⁴ are both hydrogen atoms,
z is an integer of 0 to 10,
A compound in which x and y are both 4.

(Compound B)
R ¹ and R ² are both linear alkyl groups having 8 to 15 carbon atoms,
R ³ and R ⁴ are both hydrogen atoms,
z is 7 or 8;
A compound in which x and y are both 4.

(Compound C)
R ¹ and R ² are both linear alkyl groups having 8 to 11 carbon atoms,
R ³ and R ⁴ are both hydrogen atoms,
z is 7 or 8;
A compound in which x and y are both 4.

Specific examples of the compound represented by the formula (1) include:
Bis (N ^ε -lauroyl-L-lysine) sebacylamide,
Or the salt thereof is mentioned.

  The salt of the compound represented by the formula (1) is not particularly limited, and examples thereof include alkali metal salts such as sodium salt and potassium salt, alkaline earth metal salts such as calcium salt and magnesium salt, aluminum salt, and salt with zinc. And the like, organic salts such as ammonium salts, ammonium salts, monoethanolamine salts, diethanolamine salts and triethanolamine salts, and organic salts such as basic amino acid salts such as arginine salts and lysine salts. One of these may be used, or two or more selected from the above group may be mixed and used. From the viewpoint of easy availability, handleability and the like, alkali metal salts, organic amine salts and basic amino acid salts are preferable, and sodium salts and potassium salts are particularly preferable.

Compound (1) can be produced by a method known per se or a method analogous thereto (JP 2004-323505 A, Org. Biomol. Chem., 2003, 1, 4124-4131, New J. Chem. , 2005, 29, 1439-1444). For example, as shown in the following formula, among the compounds (1), the symmetrical compound (1 ′) is obtained by reacting the N ^ω -acyl amino acid (2) with the dicarboxylic acid dichloride (3) in a suitable solvent. Can be manufactured by.

(In the formula, R ^{1 ′} is an alkyl group having 5 to 21 carbon atoms or an alkenyl group having 5 to 21 carbon atoms, and R ^{3 ′} is a hydrogen atom, an alkyl group having 1 to 22 carbon atoms or the number of carbon atoms. 2 to 22 alkenyl groups, z'is an integer of 0 or more, and x'is an integer of 2 to 4.)

N ^omega - The acylamino acid (2), for example, N ^epsilon - acyl-lysine (example: N ^epsilon - hexanoyl -L- lysine, N ^epsilon - octanoyl -L- lysine, etc.), N ^[delta] - acyl-ornithine (eg: N ^[delta] - hexanoyl -L- ornithine), N ^gamma - acyl-.alpha., .gamma.-diaminobutyric acid, and the like.
Examples of the dicarboxylic acid dichloride (3) include oxalyl chloride, malonyl chloride, succinyl chloride, glutaryl chloride, adipoyl chloride, pimeloyl chloride, suberoyl chloride, azela oil chloride, sebacyl chloride, dodecane dichloride. Oil chloride and the like can be mentioned. The usage-amount of dicarboxylic acid dichloride (3) is 0.4-0.6 equivalent normally with respect to N ( ^omega ) -acyl amino acid (2).
The solvent is not particularly limited as long as it is an inert solvent for the reaction, and examples thereof include ethers such as diethyl ether and tetrahydrofuran.

In addition, of the compound (1), the asymmetrical compound (1 ″) can be produced as follows. First, ^Nω -acyl amino acid (2) and dicarboxylic acid monochloride monoester (4) are reacted in a suitable solvent to obtain compound (5) (step 1). Then, after hydrolyzing the primary ester moiety of the obtained compound (5) in the presence of a base such as sodium hydroxide or potassium hydroxide, the carboxylic acid moiety is chlorinated using a chlorinating agent such as thionyl chloride. , N ^omega used in the step 1 - different N ^omega from acylamino acids (2) - can be prepared by reacting the acylamino acid (2 ') (step 2).

(In the formula, R ^{1 ′} , R ^{3 ′} , z ′ and x ′ are as defined above, and R ^{2 ′} is an alkyl group having 5 to 21 carbon atoms or an alkenyl group having 5 to 21 carbon atoms. , R ^{4 ′} is a hydrogen atom, an alkyl group having 1 to 22 carbon atoms or an alkenyl group having 2 to 22 carbon atoms, R ⁵ is an alkyl group such as a methyl group or an ethyl group, and y ′ is 2 to It is an integer of 4.)

As the N ^ω -acyl amino acids (2) and (2 ′), the same N ^ω -acyl amino acids as described above can be used.
When the dicarboxylic acid monochloride monoester (4) is commercially available, a commercially available product can be used as it is, and a product produced by a method known per se or a method analogous thereto can also be used.

  The compound (1) obtained by the above method is reacted with an alkali metal hydroxide such as sodium hydroxide or potassium hydroxide, an alkaline earth metal hydroxide such as calcium hydroxide, an organic amine base or the like. Can be converted into a salt of compound (1).

  The content of component (A): compound (1) or a salt thereof in the composition of the present invention is usually 0.005 to 20% by weight, preferably 0.01 to 10% by weight, based on the total amount of the composition. %, More preferably 0.01 to 5.0% by weight, and particularly preferably 0.02 to 2.5% by weight.

2. Component (B): at least one component selected from the group consisting of basic amino acids and salts thereof, and acyl basic amino acid lower esters and salts thereof, "basic amino acid" and "acyl basic amino acid lower" in the present specification. The "basic amino acid" of "ester" means an amino acid having a basic group (eg, amino group, imidazolyl group, etc.) in addition to one amino group in the molecule. Specific examples of the "basic amino acid" include arginine, lysine, histidine, ornithine and the like. Of these, arginine and lysine are preferable, and arginine is more preferable.

  As the acyl group of the “acyl basic amino acid lower ester” in the present specification, a straight chain or branched chain derivative derived from a saturated or unsaturated fatty acid having 8 to 22 carbon atoms can be used. Specific examples of the acyl group include octanoyl group, nonanoyl group, decanoyl group, undecanoyl group, lauroyl group, myristoyl group, palmitoyl group, stearoyl group, oleoyl group, linoleyl group, naturally occurring mixed fatty acid (eg, coconut oil fatty acid , Castor oil fatty acid, olive oil fatty acid, palm oil fatty acid) and the like. Preferred are lauroyl group, myristoyl group, and acyl group derived from coconut oil fatty acid.

  As the lower ester of the “acyl basic amino acid lower ester” in the present specification, an ester derived from a linear or branched alcohol having 1 to 6 carbon atoms can be used. Specific examples of the lower ester include methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, isobutyl ester, sec-butyl ester, tert-butyl ester, pentyl ester, and hexyl ester, and more preferably, It is an ethyl ester.

Specific examples of the “acyl basic amino acid lower ester” in the present specification include cocoyl arginine ethyl ester, lauroyl arginine ethyl ester and the like. Of these, cocoyl arginine ethyl ester is preferable.
The amino acid having an asymmetric carbon atom may be in an optically active form or a racemic form.

  The salt of the basic amino acid salt and the acyl basic amino acid lower ester salt is not particularly limited, and examples thereof include salts with inorganic acids such as hydrochloride, hydrobromide, sulfate, nitrate and phosphate, and formate salts. , Acetate, trifluoroacetate, oxalate, succinate, maleate, fumarate, citrate, tartrate, pyrrolidonecarboxylate, methanesulfonate, ethanesulfonate, benzenesulfonate Examples thereof include salts, p-toluenesulfonic acid salts, salts with organic acids and the like. One of these may be used, or two or more selected from the above group may be mixed and used.

  The basic amino acid salt preferably includes lysine hydrochloride, arginine hydrochloride, histidine hydrochloride and the like, and the acyl basic amino acid lower ester salt includes cocoyl arginine ethyl PCA (coconut oil fatty acid acyl arginine ethyl pyrrolidone carboxylate). ) Etc. are preferably mentioned.

  The content of the component (B) in the composition of the present invention is usually 0.005 to 20% by weight, preferably 0.05 to 10% by weight, based on the total amount of the composition.

  The pH of the composition of the present invention is not particularly limited, but it is preferably pH 5.5 to 7.5.

  The present invention also relates to cosmetics containing the composition of the present invention.

  As the cosmetics of the present invention, specifically, face wash, lotion, emulsion, cream, gel, beauty essence, pack, mask, soap, body shampoo, white powder, foundation, lipstick, cheek, eyeliner, mascara, Eye shadow, eyebrow, shampoo, conditioner, hair conditioner, hair styling agent, hair treatment and the like.

  The cosmetic of the present invention may contain components that may be added to the cosmetic in a range that does not impair the effects of the present invention. Specifically, oil agents, chelating agents, surfactants, powders, amino acids (eg, neutral amino acids, acidic amino acids, etc.), polyhydric alcohols, polyamino acids and salts thereof, water-soluble polymers, sugar alcohols and the like. Alkylene oxide adducts, lower alcohols, animal and plant extracts, nucleic acids, vitamins, enzymes, anti-inflammatory agents, bactericides, preservatives, antioxidants, UV absorbers, antiperspirants, pigments, dyes, oxidative dyes, organic and inorganic Examples include powders, pH adjusters, pearling agents, and wetting agents.

  The composition of the present invention and the cosmetic containing the composition can be produced by a conventional method.

  Next, the present invention will be specifically described with reference to manufacturing examples and examples. The present invention is not limited to the following production examples and examples. Further, "%" means "% by weight" unless otherwise specified.

[Production Example 1] Synthesis of bis (N [ ^epsilon ] -lauroyl-L-lysine) sebacylamide disodium salt N [ ^epsilon] -lauroyl-L-lysine (8.2 g, 25 mmol) was added to 70 g of water and a 25% aqueous sodium hydroxide solution ( It was dissolved in 10 g) and 80 g of diethyl ether was added. 3.3 g (14 mmol) of sebacoyl chloride was slowly added there to the ether layer. This two-layer solution was stirred for about 1 hour while keeping it at 0 ° C., and then at room temperature for 23 hours. Then, 75% sulfuric acid was added dropwise to adjust the pH to 2, and the obtained white precipitate was collected by filtration, washed well with water and dried. The obtained compound was dissolved in sodium hydroxide aqueous solution of 10% bis (N ^epsilon - lauroyl -L- lysine) was obtained sebacoyl amide disodium salt solution.

  The composition of the present invention was evaluated for stability over time, heat stability, usability (no spinnability) and usability (no squeaky feel, familiar feel, moist feel). Preparation of the composition, evaluation method and evaluation criteria are as follows.

Preparation of Compositions of Examples 1 to 7 and Comparative Examples 1 to 5 Component (A) (compound synthesized in Production Example 1) was heated and dissolved in water at 80 ° C. in advance, Component (B), glutamine or After adding to a mixture of urea and trisodium citrate, the mixture was cooled to room temperature with stirring and adjusted to pH 6.5 with citric acid. The resulting mixture was heated again at 80 ° C. for 5 minutes and cooled to room temperature. The obtained composition was completely sealed in a 30 mL glass bottle, stored at 25 ° C. for 2 weeks, and then subjected to various evaluations.

Preparation of compositions of Examples 8 to 10 and Comparative Examples 6 to 7 Component (A) (compound synthesized in Production Example 1), component (B), trisodium citrate and 3 g of water were dissolved by stirring at 80 ° C. The obtained mixture was heated and stirred at 80 ° C. in advance, di (phytosteryl / octyldodecyl) lauroylglutamate, cetyl octanoate (Examples 9 and 10), PPG-8 ceteth-20, PPG-6 decyl tetra. Added to the mixture of Decess-30 and glycerin. After cooling the mixture to 40 ° C., DPG (dipropylene glycol), BG (1,3-butylene glycol), a preservative and the remaining water were mixed, and the pH was adjusted to 6.5 with citric acid. The obtained composition was completely sealed in a 30 mL glass bottle, stored at 25 ° C. for 2 weeks, and then subjected to various evaluations.

Evaluation 1: Stability over time The glass bottle containing the composition prepared and stored as described above was tilted at 20 to 30 degrees and visually observed, and the difference from the fluidity of the composition immediately after preparation was evaluated according to the following criteria. .
⊚: No change in fluidity of the composition is observed Δ: A slight decrease in fluidity of the composition is confirmed ×: Significant decrease in fluidity of the composition is confirmed

Evaluation 2: Heat stability The composition prepared and stored as described above was further stored in a constant temperature bath of 50 ° C. for 2 weeks, and then a glass bottle containing the composition was tilted at 20 to 30 ° and visually observed at 50 ° C. The difference from the fluidity of the composition immediately before being placed in the constant temperature bath was evaluated according to the following criteria.
⊚: No change in fluidity of the composition is observed Δ: A slight decrease in fluidity of the composition is confirmed ×: Significant decrease in fluidity of the composition is confirmed

Evaluation 3: Evaluation of usability (no spinnability) When the composition prepared and stored as described above was dropped using a dropper, whether or not the composition has a thread-stripping property is described below. It was evaluated according to the standard. In the following criteria, water is ⊚, and 1% aqueous solution of sodium polyacrylate, which is a water-soluble polymer, is x.
◎: No spinnability at all 〇: Almost no spinnability △: Little spinnability ×: Clear spinnability

Evaluation 4 to 6: Evaluation of feeling of use (non-squeaky feeling, familiarity, moist feeling) The composition (40 μL) prepared and stored as described above was used to measure the skin on the inside of the forearm of 5 healthy men and women within 8 × 2 cm. It was applied to the range of, and how it was felt during or immediately after application was investigated, and the following criteria were used for scoring. In addition, the operation was performed by each of the five test subjects, the scores were scored according to the following criteria, the average score was obtained, and each item was evaluated according to the following criteria.

5 points for evaluation 4 (no squeaky feeling): No squeaky feeling and very smooth 4 points: Almost no squeaky feeling, smooth 3 points: Normal 2 points: Slightly squeaky feeling 1 point: Very squeaky feeling

Evaluation 5 (Familiarity) criteria 5 points: Very familiar to the skin 4 points: Good to the skin 3 points: Normal 2 points: Poor to the skin 1 point: Very familiar to the skin Bad for

5 points for evaluation 6 (moist feeling): Very moist feeling 4 points: Moist feeling 3 points: Normal 2 points: Moist feeling not very much 1 point: No moist feeling at all

Evaluation Criteria ⊚: Average score of 4.0 or more ○: Average score of 3.0 or more and less than 4.0 Δ: Average score of 2.0 or more and less than 3.0 ×: Average score of less than 2.0

  The results are shown in Tables 1 and 2.

  The compositions of the present invention (Examples 1 to 10) are superior in temporal stability and thermal stability, and have no spinnability, as compared with the compositions of Comparative Examples 1 to 7 which do not contain the component (B). It was shown that the usability was good. Further, it is shown that the compositions of the present invention (Examples 8 to 10) have no squeaky feeling and have a good feeling in use, as compared with the compositions of Comparative Examples 6 and 7 containing no component (B). Was done.

  INDUSTRIAL APPLICABILITY The present invention can provide a composition which exhibits a good feeling of use without squeaky feeling, is excellent in temporal stability and thermal stability, and has good usability without spinnability.

  This application is based on a patent application No. 2014-262164 filed in Japan, the contents of which are incorporated in full herein.

Claims (14)

Component (A): Formula (1)

(In the formula,
R ¹ and R ² are each independently an alkyl group having 5 to 21 carbon atoms or an alkenyl group having 5 to 21 carbon atoms,
R ³ and R ⁴ are each independently a hydrogen atom, an alkyl group having 1 to 22 carbon atoms or an alkenyl group having 2 to 22 carbon atoms,
z is an integer of 0 or more,
x and y are each independently an integer of 2 to 4. ) Or a salt thereof;
And component (B): a composition containing at least one selected from the group consisting of cocoyl arginine ethyl ester pyrrolidone carboxylate and lauroyl arginine ethyl ester hydrochloride .   The composition according to claim 1, wherein the component (A) is a compound in which z is an integer of 0 to 10 in the formula (1) or a salt thereof.   The composition according to claim 1 or 2, wherein the component (A) is a compound in which z is 7 or 8 in the formula (1) or a salt thereof.   The composition according to any one of claims 1 to 3, wherein the component (A) is a compound in which x and y are both 4 in the formula (1) or a salt thereof. The component (A) is a compound or a salt thereof, wherein in the formula (1), R ¹ and R ² are each independently a linear alkyl group having 5 to 15 carbon atoms. The composition according to item 1. The composition according to any one of claims 1 to 5, wherein the component (A) is a compound in which R ³ and R ⁴ are both hydrogen atoms in the formula (1) or a salt thereof. In the component (A), in the formula (1), R ¹ and R ² are each independently a linear alkyl group having 5 to 15 carbon atoms, and R ³ and R ⁴ are both hydrogen atoms. , Z is an integer of 0 to 10, and x and y are both 4 or a compound thereof, the composition according to any one of claims 1 to 5. In the component (A), in the formula (1), R ¹ and R ² are both linear alkyl groups having 5 to 15 carbon atoms, R ³ and R ⁴ are both hydrogen atoms, and z is The composition according to any one of claims 1 to 5, which is 7 or 8 and x and y are both 4 or a salt thereof. Component (A), bis (N ^epsilon - lauroyl -L- lysine) sebacoyl amide, and bis - a (N ^epsilon octanoyl -L- lysine) or salts thereof selected from sebacoyl amide claim 1 9. The composition according to any one of items 8 to 8. The composition according to any one of claims 1 to 9, wherein the salt of component (A) is a disodium salt. Component (A) is bis (N ^ε -Lauroyl-L-lysine) sebacylamide, and bis (N ^ε 10. The composition of claim 9, which is a disodium salt of a compound selected from -octanoyl-L-lysine) sebacylamide.   The composition according to any one of claims 1 to 11, which contains the component (A) in an amount of 0.005 to 20% by weight based on the total amount of the composition.   The composition according to any one of claims 1 to 12, which contains the component (B) in an amount of 0.005 to 20% by weight based on the total amount of the composition. Cosmetics containing the composition of any one of Claims 1-13.