JP6918359B2 - Deodorant composition for axillary odor - Google Patents

Description

The present invention relates to a deodorant composition having an excellent deodorant and deodorant effect on body odors such as axillary odor.

Axillary odor is a body odor generated by decomposition of secretions from three sweat glands, apocrine sweat glands, sebaceous glands, and ericune sweat glands (leakage secretory glands) in the axilla by indigenous skin bacteria.
Fats and proteins contained in apocrine sweat secreted from the apocrine sweat glands in the axillary region are decomposed by indigenous skin bacteria, and sebum secreted by the sebaceous glands is added to this, and apocrine sweat and sebum are separated by ericun sweat. It is spread and gives off an axillary odor. Of the three sweat glands, the apocrine sweat gland has the greatest effect on axillary odor, and those who secrete a large amount from the apocrine sweat gland are more likely to develop so-called "armpits".
Since axillary odor has a particularly large effect on systemic body odor, there is an increasing need for deodorant products that suppress it.

As a method of suppressing axillary odor, there is a method of blending an antibacterial component that suppresses or sterilizes the growth of indigenous skin flora that produces the axillary odor-causing component. Cymene-5-ol (isopropylmethylphenol) is known as a typical antibacterial ingredient that can be blended and used in cosmetics and quasi-drugs applied to the skin (for example, Patent Document 1).
However, although cymene-5-ol exerts some effect on various skin flora indigenous bacteria, it is difficult to obtain a sufficient deodorizing effect by cymene-5-ol alone. Therefore, a deodorant agent in which cymene-5-ol is used in combination with other ingredients has been reported. Specifically, triclosan (Patent Document 2), lysozyme and / or a salt thereof (Patent Document 3), chlorhexidine gluconate (Patent Document 4) and the like have been reported as other components.

Japanese Unexamined Patent Publication No. 8-12545 Japanese Unexamined Patent Publication No. 2006-96719 Japanese Unexamined Patent Publication No. 2007-14771 Japanese Patent No. 5275637

On the other hand, in the deodorant agent, the use of a component derived from a natural product, particularly a plant-derived component, is desired by consumers from the viewpoint of safety as well as an effect of suppressing odor. However, no deodorant agent containing a plant-derived component capable of effectively exerting an effective antibacterial action against axillary odor has been reported so far.

Further, since the axillary portion has a large amount of sweating, there is a problem that even if the odor suppressing effect is high, if the component is easily discharged by sweat, the odor suppressing cannot be expected to last for a long period of time. However, some conventional deodorant compositions cannot cope with the outflow of the active ingredient due to sweat, and in reality, many of them do not sufficiently exhibit the deodorizing and deodorizing effects.

Under such circumstances, an object of the present invention is to provide a useful deodorant composition which is excellent in suppressing axillary odor and in which the active ingredient is less likely to flow out due to sweat.

As a result of diligent studies to solve the above problems, the present inventor exerts an excellent antibacterial action synergistically by using Simen-5-ol in combination with a specific plant extract. We have found that by combining with other predetermined components, a composition having an excellent effect of suppressing axillary odor and in which the active ingredient is less likely to flow out due to sweat can be obtained, and the present invention has been completed.

That is, the present invention relates to the following invention.
<1> A deodorant composition for axillary odor containing the following components.
Component (A): Simen-5-ol, persimmon tannin, tea extract and dipotassium glycyrrhizinate component (B): Zinc phenolsulfonate and artichoke extract component (C): Pear juice fermented liquid component (D): Human type Ceramide compound <2> Further component (E): The deodorant composition for axillary odor according to <1>, which contains one or more components selected from shakyaku extract, hamamelis extract, pear extract and aloe extract.
<3> The deodorant composition for axillary odor according to <1> or <2>, which is a liquid agent, lotion agent, gel agent, emulsion agent or cream agent.

According to the present invention, there is provided a useful deodorant composition which has an excellent effect of suppressing axillary odor and is less likely to cause the active ingredient to flow out due to sweat.

Hereinafter, the present invention will be described in detail by showing examples and the like, but the present invention is not limited to the following examples and the like, and can be arbitrarily modified and implemented without departing from the gist of the present invention. In addition, in this specification, "~" shall be used as an expression including numerical values or physical quantities before and after it. Further, in the present specification, "extract" and "extract" are used as synonyms.

The present invention relates to an axillary odor deodorant composition containing the following components as essential components.
Component (A): Simen-5-ol, persimmon tannin, tea extract and dipotassium glycyrrhizinate component (B): Zinc phenolsulfonate and artichoke extract component (C): Pear juice fermented liquid component (D): Human type Ceramide compound

<Ingredient (A)>
The component (A) is an antibacterial component, and is characterized by combining a plant-derived component together with cymene-5-ol.
Cymene-5-ol, also called isopropylmethylphenol, is a bactericidal component that exerts some effect on various indigenous skin flora. On the other hand, it is difficult to obtain a sufficient bactericidal action with cymene-5-ol alone.
In the present invention, by blending the plant-derived components persimmon tannin, tea extract and dipotassium glycyrrhizinate in combination with cymene-5-ol, an excellent antibacterial effect that cannot be obtained by cymene-5-ol alone can be obtained. Obtainable.

The raw material plants for component (A) are persimmon (persimmon), tea (tea), and licorice.
The site of use of the raw material plant may be any site of the plant such as leaves, stems, roots, flowers, fruits, trunks and branches, as long as the required extract having antibacterial activity can be obtained.
The plant extract can be obtained by extracting an appropriate part of the raw material plant with an appropriate solvent, and the solvent is not limited as long as the required action can be obtained, for example, water (warm water, hot water). ), Ethanol, and hydrous ethanol can be used. Moreover, the squeezed juice can be used as it is. As these plant extracts, commercially available ones can be used.

Persimmon (Persimmon) is a kind of deciduous tree of the family Ebenaceae. Examples of the site to be used include fruits, which are sites containing tannin. Since persimmon tannin acts directly on the odorous component, the deodorizing effect is improved by including it.

Tea (Tea plant) is an evergreen large shrub of the genus Camellia of the Theaceae family. Examples of the site to be used include leaves and stems.

Licorice is a perennial plant of the leguminous family that grows naturally in the Mediterranean region, northern China, North America, etc., and is a raw material plant for dipotassium glycyrrhizinate. The site to be used may be a site containing dipotassium glycyrrhizinate, and is usually a root.

The blending amount of the component (A) is usually 0.01 to 5% by mass in the deodorant composition as the total amount of each component constituting the component (A). If the amount of the component (A) is too small, the antibacterial action may be insufficient, and if it is too large, excessive skin irritation may occur.

In the component (A), the mixing ratio of cymene-5-ol and other components (persimmon tannin, tea extract and dipotassium glycyrrhizinate) is not particularly limited, but preferably cymene-5-ol and other components. The weight ratio of is 0.1: 1 to 10: 1. If the content of other components is too small or too large, a synergistic enhancing effect of antibacterial activity with cymene-5-ol cannot be expected, which is not preferable.
The blending amount of cymene-5-ol was appropriately determined in the range of 0.001 to 3% by mass, and the blending amounts of other components (persimmon tannin, tea extract and dipotassium glycyrrhizinate) were 0.001 to 3, respectively. It is appropriately determined in the range of mass%.

<Ingredient (B)>
The component (B), zinc phenol sulfonate (zinc paraphenol sulfonate), has an astringent action and reacts with sweat and proteins contained in the skin to coagulate blood vessels and tissues, and from pores and sweat glands. It has the effect of suppressing sweat secretion.
By blending zinc phenol sulfonate and artichoke extract, which is a plant-derived component, in combination, it has an antiperspirant effect superior to that of zinc phenol sulfonate alone. Therefore, when the deodorant composition for axillary odor of the present invention is used, it is possible to prevent the component (A) (and other components) having an antibacterial action from flowing out from the axillary portion due to sweat.

Artichoke is a perennial plant belonging to the genus Cirsium in the family Asteraceae. The artichoke extract can be obtained by extracting the buds and leaves of the raw material plant with an appropriate solvent, and the solvent is not limited as long as the required action can be obtained, for example, water (warm water, heat). Water), ethanol, and hydrous ethanol can be used. Moreover, the squeezed juice can be used as it is. Commercially available artichoke extract can be used.

The blending amount of the component (B) is not particularly limited as long as the effect of the present invention is exhibited, and the component (B) is appropriately determined within a range in which the deodorant / deodorant effect can be sufficiently exhibited based on the component (A). The total amount of each constituent component is usually 0.01 to 5% by mass in the deodorant composition. If the amount of the component (B) is too small, the effect of sustaining the deodorant / deodorant effect may be insufficient, and if it is too large, excessive skin irritation may occur.

In the component (B), the blending ratio of zinc phenolsulfonate and artichoke extract is not particularly limited, but the weight ratio of zinc phenolsulfonate and artichoke extract is preferably 0.1: 1 to 10: 1.
The blending amount of zinc phenol sulfonate is appropriately determined in the range of 0.001 to 3% by mass, and the blending amount of the artichoke extract is appropriately determined in the range of 0.001 to 3% by mass.

<Component (C)>
The pear juice fermented liquor, which is the component (C), is lactic acid fermented pear juice, which is a plant of the genus Pyrus of the Rosaceae family native to Europe, and has a moisturizing effect by sugars and minerals. In addition, the component (C) promotes the penetration of the component (A) and the component (B) into the skin due to the keratin softening and the mild peeling action of lactic acid. In addition, an action of improving an excellent bactericidal action can be expected by a synergistic action with the component (A). Moreover, since the component (C) is a plant-derived component, it has little adverse effect on the skin.

The fermented green pear fruit juice can be obtained by a known production method, and a commercially available product can be used.

The blending amount of the component (C) is usually 0.001 to 3% by mass in the deodorant composition. If the amount of the component (C) is too small, the effect of promoting the penetrating power may be insufficient, and if it is too large, excessive skin irritation may occur.

<Component (D)>
The human ceramide compound, which is the component (D), is a compound having a structure equivalent to that of ceramide existing in the human skin stratum corneum, and improves the moisturizing function such as moisturizing the skin and prevents water from evaporating from the skin. However, it has the function of preventing external stimuli and the invasion of bacteria. Therefore, by blending the component (D), in addition to further promoting the actions of the above-mentioned components (A) to (C), it is possible to suppress the invasion of the axillary odor-causing bacteria from the outside.

The component (D) may be not only ceramide but also glycosphingolipid in which a sugar is bound to ceramide.

Examples of the human ceramide compound include ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6, ceramide 6II, ceramide 7, ceramide 8, ceramide 9 or ceramide 10, and one or 2 of these. A mixture of more than a seed can be used. Among these, it is preferable to contain ceramide 3 (N-stearoylphytosphingosine).

In addition to the components (A) to (D), any component can be added to the deodorant composition for axillary odor of the present invention as long as the effects of the present invention are not impaired.
Optional components include, for example, dispersion medium (solvent) components, deodorant components, anionic surfactants, cationic surfactants, amphoteric ionic surfactants, nonionic surfactants, animal and plant extracts, vitamins, amino acids. , PH adjusters, powders such as silica, talc, bentonite, moisturizers, surfactants, preservatives, refreshing agents, anti-inflammatory agents and the like.

In the deodorant composition for axillary odor of the present invention, a dispersion medium can be appropriately selected according to its form. For example, as a dispersion medium (solvent) component, water (preferably purified water); higher alcohols such as lauryl alcohol and stearyl alcohol; glycerin, diglycerin, dipropylene glycol, 1,3-butanediol, 1,2-pentanediol. Etc., Polyhydric alcohols; etc. may be appropriately blended. These may be appropriately mixed and used.

Hereinafter, the component (E), which is an arbitrary plant-derived component suitable to be blended in the deodorant composition for axillary odor of the present invention, will be described, but the optional component is not limited thereto. The blending amount of the component (E) is appropriately selected within a range that does not impair the effects of the present invention.

The target extract can be obtained by extracting the raw material with an appropriate solvent, and as the solvent, for example, water (warm water, hot water), ethanol, or hydrous ethanol can be used. .. Moreover, the squeezed juice can be used as it is. As these extracts, commercially available ones can be used.

As the component (E), it is preferable to blend one or more components selected from peony extract, witch hazel extract, hypericum extract and aloe extract. These components also have an action of promoting the penetration of the components (A) to (D) into the skin. In addition, an action of improving an excellent bactericidal action can be expected by a synergistic action with the component (A).

Peony is a perennial plant of the Peony family. Examples of the part to be used include a flower part and a leaf part.

Hamamelis is a deciduous small tree of the witch hazel family, witch hazel, and is called American witch hazel. Examples of the site to be used include a leaf portion and a bark portion.

Hypericum is a perennial plant of the genus Hypericum in the family Hypericum. Among the hypericum, St. John's wort is preferably used. Examples of the site to be used include a flower part, a leaf part and a stem part.

Aloe is a succulent plant belonging to the genus Aloe of the subfamily Asphodelaceae. Among aloe, Kidachi aloe is preferably used. Examples of the site to be used include leaves.

As the component (C), it is preferable to include all of peony extract, witch hazel extract, hypericum extract and aloe extract.

The total amount of these extracts is usually 0.001 to 10% by mass in the deodorant composition. The blending amount of each extract is appropriately determined in the range of 0.001 to 3% by mass. If the amount is too small, the effect of promoting the penetrating power may be insufficient, and if the amount is too large, excessive skin irritation may occur.

In addition, the deodorant composition for axillary odor of the present invention can condition the skin, and thus can be used to condition the skin. , Placenta extract and grape leaf extract are preferably contained.

Sanguisorba is a plant belonging to the genus Sanguisorba in the family Rosaceae. Examples of the site to be used include leaves.

Arnica is a perennial plant belonging to the genus Arnica in the family Asteraceae, and is also called rabbit giku. The part to be used includes a flower part.

Rosemary is an evergreen shrub belonging to the Labiatae family. Examples of the site to be used include leaves.

Starfruit is an evergreen tree of the genus Carambola of the family Oxalis. Examples of the site to be used include leaves.

Horse chestnut is a large deciduous tree of the Aesculus family and is also called horse chestnut. Examples of the site to be used include fruits, leaves, bark and the like.

Himefuuro is an annual or perennial herb that belongs to the genus Geraniaceae of the family Geraniaceae. Examples of the site to be used include seeds.

Ivy is an angiosperm of the Araliaceae family. Examples of the site to be used include a leaf portion and a stem portion.

Yokuinin is a component contained in the flesh of Coix seeds. Examples of the site to be used include seeds excluding the seed coat of Coix seeds.

As the placenta, an extract of placenta derived from mammals such as pigs and horses can be used. As the extraction method, a conventionally known method can be used. As the placenta, a commercially available placenta can be used.

Grapes are vine deciduous shrubs of the vine family (Vitaceae). The grape varieties are not particularly limited. Examples of the site to be used include leaves.

The total amount of these components is usually 0.001 to 10% by mass, preferably 0.01 to 5% by mass in the deodorant composition. The blending amount of each extract is appropriately determined in the range of 0.001 to 3% by mass.
If the amount of the component (E) is too small, the effect of adjusting the condition of the skin may be insufficient, and if it is too large, the effect may not be obtained.

<Form and usage of deodorant composition>
The form of the deodorant composition for axillary odor of the present invention is not limited and is appropriately determined depending on the method used, but is usually semi-solid or liquid due to the applicability to the axillary region. Specifically, it can be used in various forms such as liquids, lotions, gels, emulsions, and creams. Of these, creams are the preferred form. The deodorant composition for axillary odor of the present invention may be produced by a generally known method according to its form.

The deodorant composition for axillary odor of the present invention has an excellent deodorizing and deodorizing effect on axillary odor. The target of the deodorant composition for axillary odor of the present invention is mainly axillary odor, but it can also be used for other parts (scalp, face, trunk, armpits, crotch, sole, etc.).

The method of using the axillary odor deodorant composition of the present invention is not particularly limited, but it may be applied or sprayed according to the form thereof so as to be in direct contact with the axillary portion.

Although the present invention has been described above, matters not explicitly disclosed in the above description do not deviate from the scope normally practiced by those skilled in the art, and can be easily assumed by those skilled in the art. Can be adopted and is not restrictive.

Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited thereto.

(Sample preparation)
The following ingredients were mixed until evenly to prepare the deodorant composition (creamy) of the example.
<Ingredient (A)>
Cymene-5-ol: 0.5 parts by weight Persimmon tannin: 0.1 parts by weight Tea extract: 0.1 parts by weight Dipotassium glycyrrhizinate: 0.1 parts by weight <Component (B)>
Zinc Phenol Sulfonate: 2 parts by weight Artichoke Extract: 0.1 parts by weight <Component (C)>
Fermented pear juice: 0.1 parts by weight <Component (D)>
N-stearoyl phytosphingosine (ceramide 3): 0.2 parts by weight <model base material component>
Mixture containing 40 parts by weight of butylene glycol, 60 parts by weight of purified water, 0.5 parts by weight of surfactant

Evaluation 1: Bacterial growth suppression test Staphylococcus aureus was used as a model bacterium of the axillary odor-causing bacterium, and the difference in bacterial growth depending on the presence or absence of the composition (creamy) of the example was evaluated. The evaluation was performed by the egg yolk-added mannitol salt balance plate culture method.
First, Staphylococcus aureus isolated and cultured from humans was diluted 105-fold to prepare a Staphylococcus aureus solution. 5 g of the composition of the example was added to 10 mL of the obtained solution, and the mixture was stirred until uniform to obtain a test solution.
0.1 ml of the obtained test solution was smeared on egg yolk-added mannitol salt agar medium, and colonies of grown microorganisms were observed at 35 ° C. for 0 hours, 24 hours, 48 hours, and even after 48 hours. No colonization was confirmed.

For comparison, when the Staphylococcus aureus solution (Comparative Example) was cultured under the same conditions, clear colonization was confirmed after 24 hours, and it was confirmed that the colonies were growing after 48 hours of culture.

Evaluation 2: Ingredient outflow test As a model test, after applying the composition (creamy) of Example 1 to pig skin, it is immersed in artificial sweat (acetic acid) adjusted to about 37 ° C., and the durability time to adhere to the epidermis. Was evaluated. As a result, it was visually confirmed that there was no runoff after 1 hour and that the composition of Example 1 was attached to the epidermis even after 24 hours.

Evaluation 3: Evaluation by monitor Evaluation 3-1. Deodorant evaluation Female subjects (5 subjects) were asked to apply the composition of the example (about 1 g) to one axilla and to perform daily life without applying anything to the other axilla. .. Measurements were performed with an odor sensor before the evaluation (0 hours) and 10 hours after the start of application, and the respective numerical values (average values) were compared.
As a result, the value of the axilla to which nothing was applied was 29 before the evaluation, whereas it was 104 after 10 hours, whereas the value of the axilla to which the composition of Example was applied was 28, which was the value before the evaluation. It was 32 after 10 hours. From this result, it was confirmed that the composition of the example had an excellent effect of suppressing axillary odor.

In addition, in order to investigate the effect of sweat outflow, female subjects (5 subjects) were asked to perform exercise (running, etc.) accompanied by sweating for 1 hour, and the same test was conducted. Specifically, for 5 female subjects, no treatment was applied to each axillary part, and the composition of the example to be evaluated was applied to the other axillary part, and the numerical value after 1 hour of exercise (1 hour exercise). The average value) was compared with the value before exercise (average value).
As a result, the value of the axilla to which nothing was applied was 36 before the evaluation, whereas it was 39 after the exercise, whereas the value of the axilla to which the composition of Example was applied was 35, which was the value before the evaluation. It was 105 after exercise. From this result, it was confirmed that the composition of the example was not washed away by sweat, and the excellent axillary odor suppressing action was maintained.

Evaluation 3-2. Evaluation of usability (stickiness) The five female subjects were subjected to a sensory evaluation of the stickiness of the skin during use of the composition of Example 1 based on the following criteria. The results were evaluated from the average value of 5 subjects according to the following evaluation criteria and judgment criteria.
[Evaluation criteria]
3 points: Very sticky 2 points: A little sticky 1 point: No stickiness

The average value of the five female subjects in daily life was 1.2, and the average value of the five female subjects after exercise was 1.0. From this result, it was confirmed that the composition of Example 1 had an excellent usability.

(Product example)
The following products (creamy) were prepared.
Simene-5-ol: 0.5 parts by weight Persimmon tannin: 0.1 parts by weight Tea extract: 0.1 parts by weight Dipotassium glycyrrhizinate: 0.1 parts by weight Zinc phenolsulfonate: 2 parts by weight Artichoke extract: 0. 1 part by weight Pear juice fermented liquid: 0.1 part by weight N-stearoyl phytosphingocin (ceramide 3): 0.2 part by weight Shakuyaku extract: 0.1 part by weight Hamamelis extract: 0.1 part by weight Otogirisou extract: 0. 1 part by weight Aloe extract: 0.1 part by weight <model base material component>
Mixture containing 40 parts by weight of butylene glycol, 60 parts by weight of purified water, 0.5 parts by weight of surfactant

The deodorant composition for axillary odor of the present invention is excellent in the effect of suppressing axillary odor, and the active ingredient is less likely to flow out due to sweat, and is useful in fields such as hygiene products and cosmetics.

Claims (3)

A deodorant composition for axillary odor, which comprises the following components.
Component (A): Simen-5-ol, persimmon tannin, tea extract and dipotassium glycyrrhizinate component (B): Zinc phenolsulfonate and artichoke extract component (C): Pear juice fermented liquid component (D): Human type Ceramide compound Further component (E): The deodorant composition for axillary odor according to claim 1, which contains one or more components selected from witch hazel extract, witch hazel extract, otogirisou extract and aloe extract. The deodorant composition for axillary odor according to claim 1 or 2, which is a cream agent.