JP6937151B2 - Medical tubular members, foreign body removal devices and foreign body removal catheters - Google Patents

Description

The present invention relates to a medical tubular member, a foreign body removing device and a foreign body removing catheter.

Conventionally, as a medical tubular member inserted into a tubular tissue such as a blood vessel, for example, a thrombus removing device for removing a thrombus from a blood vessel wall is known (see, for example, Patent Document 1).

Special Table 2016-513524

By the way, in order to insert the thrombectomy device to a predetermined position where a thrombus is present without damaging the blood vessel wall of a thin and winding blood vessel, it is desirable that the thrombectomy device has a structure that can be smoothly bent.
Therefore, it is conceivable to form a plurality of slits in the thrombectomy device, but when bent, stress is concentrated on the ends of the slits to cause damage such as cracks, or the opposing edges of the slits are partially formed. When the contact is made, the load may be concentrated on the contacted portion and deformation may occur.

Such problems can also occur in tubular members that are inserted into tubular tissues other than blood vessels (eg, gastrointestinal tract, bile duct, etc.).

The present invention has been made in view of the above circumstances, and an object of the present invention is to provide a medical tubular member which can be smoothly bent and can suppress breakage or deformation when bent. It is an object of the present invention to provide a foreign body removing device and a foreign body removing catheter provided with the medical tubular member.

In order to achieve the above-mentioned object, the medical tubular member, the foreign matter removing device and the foreign matter removing catheter according to the present invention are characterized by the following (1) to (6).
(1) A tubular medical tubular member that is inserted into a tubular tissue.
The inserted member inserted into the tubular tissue and expandable and contractible in the radial direction substantially orthogonal to the axial direction is integrally formed on at least one of the front side in the insertion direction and the rear side in the insertion direction.
A plurality of slits are formed through the tube wall of the medical tubular member and along the direction diagonally intersecting the axial direction.
Each of the plurality of slits
The edges facing each other are gradually brought closer to each other toward both ends in the extending direction of the slit, and the width is narrowed.
It is characterized in that both ends thereof bulge so as to form a round hole shape.
(2) The slit is characterized in that the slit exists on a straight line substantially parallel to the axial direction at any position in the circumferential direction.
(3) The plurality of slits are arranged so as to be spirally connected in the circumferential direction.
(4) The plurality of slits are characterized in that adjacent ones in the axial direction are arranged so as to be displaced in the circumferential direction.
(5) A foreign matter removing device configured to remove or recover foreign matter in a tubular tissue.
A member to be inserted that is inserted into the tubular tissue and can be expanded or contracted in the radial direction substantially orthogonal to the axial direction.
Wherein among the insertion direction front side and the insertion direction rear side of the insertion member is formed integrally on at least one, and a cylindrical tubular member which is inserted into the tubular tissue,
The tubular member is formed with a plurality of slits penetrating the tube wall and along a direction diagonally intersecting the axial direction.
Each of the plurality of slits
The edges facing each other are gradually brought closer to each other toward both ends in the extending direction of the slit, and the width is narrowed.
It is characterized in that both ends thereof bulge so as to form a round hole shape.
(6) A foreign matter removing catheter for removing or collecting foreign matter in a tubular tissue.
Catheter body and
A foreign body removing device located at the distal portion of the catheter body and configured to remove or recover foreign body in the tubular tissue.
The foreign matter removing device is
A member to be inserted that is inserted into the tubular tissue and can be expanded or contracted in the radial direction substantially orthogonal to the axial direction.
Wherein among the insertion direction front side and the insertion direction rear side of the insertion member is formed integrally on at least one, and a cylindrical tubular member which is inserted into the tubular tissue,
The tubular member is formed with a plurality of slits penetrating the tube wall and along a direction diagonally intersecting the axial direction.
Each of the plurality of slits
The edges facing each other are gradually brought closer to each other toward both ends in the extending direction of the slit, and the width is narrowed.
It is characterized in that both ends thereof bulge so as to form a round hole shape.

According to the medical tubular member having the configuration of (1) above , at least one of the front side in the insertion direction and the rear side in the insertion direction of the inserted member which is inserted into the tubular tissue and can be expanded and contracted in the radial direction substantially orthogonal to the axial direction. It is integrally formed on one side, penetrates the tube wall of the medical tubular member, and a plurality of slits are formed along the direction diagonally intersecting the axial direction, so that good flexibility is imparted and the tubular tissue is curved. Even if it does, it can be smoothly bent in this tubular tissue. Further, since both ends of the slit in the extending direction bulge so as to form a round hole shape, the stress generated on the end side when bent, particularly the stress concentrated on the end is dispersed to the surroundings, and this end. It is possible to suppress damage such as cracks in the part. Further, since the edges of the slits facing each other are gradually brought closer to each other toward both ends in the extending direction of the slit and the width is narrowed, the edges facing each other on both ends of the slit can easily come into close contact with each other. Therefore, it is possible to suppress the deformation caused by the edge portion of the slit partially abutting and the load being concentrated on the abutting portion.
According to the medical tubular member having the configuration of (2) above, since the slit exists on a straight line substantially parallel to the axial direction at any position in the circumferential direction, the axial direction can be obtained at any position in the axial direction. It can be smoothly bent in all directions where it intersects with, and high flexibility can be obtained.
According to the medical tubular member having the configuration of (3) above, by arranging a plurality of slits in a spiral shape in the circumferential direction, the degree of freedom of bending is increased and the direction of intersection with the axial direction is smoother. Can be bent.
According to the medical tubular member having the configuration of (4) above, since the plurality of slits adjacent to each other in the axial direction are arranged so as to be offset in the circumferential direction, the degree of freedom of bending is increased and the axial direction is smoother. Can be bent in any direction that intersects with.
According to the foreign matter removing device having the configuration of (5) above, not only the same effect as that of (1) can be obtained, but also when the foreign matter removing device is inserted into a predetermined position in the tubular tissue where foreign matter needs to be removed or collected, the foreign matter removing device is inserted. Even if the tubular tissue is curved, the medical tubular member of the foreign matter removing device can be smoothly bent, and the foreign matter removing device can be smoothly transported to a predetermined position in the tubular tissue. Thereby, the foreign matter in the tubular tissue can be easily removed or recovered.
According to the foreign matter removing catheter having the configuration of (6) above, not only the same effect as (1) can be obtained, but also the foreign matter removing device can be smoothly tubularized in substantially the same manner as the foreign matter removing device of the present invention described above. The foreign matter in the tubular tissue can be easily removed or recovered by inserting the foreign matter into a predetermined position requiring removal or recovery of the foreign matter in the above.

According to the present invention, it can be smoothly bent, and it is possible to suppress the occurrence of breakage or deformation when bent.

The present invention has been briefly described above. Further, the details of the present invention will be further clarified by reading through the embodiments described below (hereinafter referred to as "embodiments") with reference to the accompanying drawings. ..

1A and 1B are views for explaining a medical tubular member according to the present embodiment, FIG. 1A is a side view of the medical tubular member, and FIG. 1B is a part of FIG. 1A. It is an enlarged view. FIG. 2 is a diagram showing the shape of a slit formed in the medical tubular member according to the present embodiment. FIG. 3 is a diagram schematically showing an arrangement of slits of a medical tubular member according to the present embodiment. FIG. 4 is a side view of the medical tubular member according to the present embodiment in a bent state. FIG. 5 is a side view of the medical tubular member according to the reference example in a bent state. FIG. 6 is a schematic configuration diagram illustrating a foreign matter removing catheter according to the present embodiment. 7A and 7B are views showing the internal structure of the foreign matter removing catheter according to the present embodiment, FIG. 7A is a cross-sectional view when the retriever is expanded, and FIG. 7B is a cross-sectional view when the retriever is contracted. Is. 8A and 8B are views for explaining how to use the foreign matter removing catheter, and FIGS. 8A to 8F are schematic cross-sectional views of foreign matter removing positions in the tubular tissue, respectively. FIG. 9 is a diagram schematically showing an arrangement of slits of a medical tubular member according to a modified example. FIG. 10 is a diagram showing the shape of another slit formed in the medical tubular member.

Hereinafter, examples of embodiments according to the present invention will be described with reference to the drawings.

(Medical tubular member)
1A and 1B are views for explaining a medical tubular member according to the present embodiment, FIG. 1A is a side view of the medical tubular member, and FIG. 1B is a part of FIG. 1A. It is an enlarged view.

As shown in FIGS. 1A and 1B, the medical tubular member (hereinafter, simply referred to as a tubular member) 10 according to the present embodiment is, for example, a pipe-shaped member having a circular cross section. The tubular member 10 is a member that is inserted into a tubular tissue such as a blood vessel.

Examples of the material constituting the tubular member 10 include stainless steel, titanium alloy, Ni-Ti alloy, Ni-Ti-Co alloy, Ni-Ti-Cu alloy, Au-Cd alloy, Cu-Al-Ni alloy and the like. A representative known metal or metal alloy can be preferably used. Further, by using an alloy having X-ray contrast property as a material, it may be used as an X-ray opaque marker. In this case, the position of the tubular member 10 can be confirmed from outside the body.

A plurality of slits 20 are formed in the tube wall 11 of the tubular member 10. These slits 20 are formed by, for example, laser machining, penetrating the tube wall 11 of the tubular member 10 in and out. Further, the plurality of slits 20 are formed along a direction intersecting the axis X direction of the tubular member 10, respectively. Specifically, the plurality of slits 20 have substantially the same shape and dimensions, and are formed so as to be spirally connected in the circumferential direction (details will be described later; see FIG. 3).
As the processing method of the slit 20, for example, laser processing can be preferably used, but it may be formed by another processing method.

FIG. 2 is a diagram showing the shape of a slit formed in the medical tubular member according to the present embodiment.
As shown in FIG. 2, both ends of the slit 20 are formed with hole portions 21 bulging so as to form a round hole shape (for example, a circular shape in a plan view).
Specifically, for example, it is preferable that the diameter, the center position, and the like of the hole 21 are defined so that the area of the hole 21 is larger than that of a semicircle when the hole 21 is assumed to be circular. That is, for example, when the hole 21 is assumed to be circular, the diameter is larger than the width of the narrowest portion of the slit 20 facing each other (described later), and the center of the hole 21. It is preferable that the positions are arranged on the outer side (upper side or lower side in FIG. 2) of the edge portions 22 facing each other.
Although not shown, the diameter of the hole 21 may be substantially equal to the width of the narrowest portion of the edge 22 when the hole 21 is assumed to be circular.

Further, the slit 20 is formed in such a shape that the edge portions 22 facing each other gradually narrow in width from the central side toward the end portion. Specifically, the edges 22 of the slits 20 facing each other have the widest substantially central portion in the extending direction of the slit 20. The width of the substantially central portion is larger than, for example, the diameter when the hole portion 21 is assumed to be circular. Further, the edges 22 of the slits 20 facing each other extend linearly so as to be inclined at substantially the same angle with respect to the extending direction with the substantially central portion of the slit 20 in the extending direction as a boundary. That is, the edge portions 22 facing each other are inclined so as to form a substantially "H" shape on each end side with the substantially central portion in the extending direction of the slit 20 as a boundary.
The edges 22 of the slits 20 facing each other may be formed in a substantially arc shape, for example.

The tubular member 10 is, for example, a pipe having an outer diameter of 1.6 mm (inner diameter of 1.4 mm) to an outer diameter of 2.45 mm (inner diameter of 2.05 mm). Further, the diameters of the holes 21 at both ends of the slit 20 formed in the tubular member 10 are set to, for example, 0.14 mm. The hole portion 21 preferably has a diameter of 0.08 mm or more and 0.20 mm or less.

FIG. 3 is a diagram schematically showing an arrangement of slits of a medical tubular member according to the present embodiment.
As shown in FIG. 3, the slit 20 is formed so as to be slightly inclined with respect to the straight line A orthogonal to the axis X. These plurality of slits 20 have the same shape and the same dimensions. As a result, in the tubular member 10, the slits 20 are formed so as to be spirally connected in the circumferential direction, and the interslit region portion 24 between the slits 20 spirally connected to each other in the circumferential direction is spirally arranged. .. The slit 20 is arranged so that the slit 20 exists on a straight line B substantially parallel to the axis X direction at any position in the circumferential direction of the tubular member 10. The plurality of slits 20 may have different shapes and may have different dimensions.

FIG. 4 is a side view of the medical tubular member according to the present embodiment in a bent state.
As shown in FIG. 4, in the tubular member 10 having a plurality of slits 20 along the direction intersecting the axis X direction, the slits 20 are opened on the extending side (upper side in FIG. 4) by applying a bending force. At the same time, the slit 20 is closed on the bending side (lower side in FIG. 4).

As described above, according to the medical tubular member 10 according to the present embodiment, by having a plurality of slits 20 along the direction intersecting the axis X direction, good flexibility is imparted to the thin and winding blood vessel. However, it is bent along its shape and smoothly inserted without damaging the blood vessel wall.

Here, a tubular member 10A according to a reference example having straight slits 20 having no holes 21 at both ends will be described with reference to FIG.
FIG. 5 is a side view of the medical tubular member according to the reference example in a bent state.

As shown in FIG. 5, in the tubular member 10A according to this reference example, since there are no holes 21 at both ends of the slit 20, the slit 20 is torn by the stress concentrated on both ends of the slit 20 to be opened on the extending side. There is a risk of damage. Further, on the bending side, a gap is generated between the edge portions 22 of the slit 20, and the edge portions 22 of the slit 20 are partially in contact with each other, and the load is concentrated on the contacted portion. May cause deformation.

On the other hand, according to the tubular member 10 according to the present embodiment, both ends of the slit 20 in the extending direction bulge so as to form a round hole shape, so that stress generated on the end side when bent, particularly , The stress concentrated on the end is dispersed to the surroundings, and damage such as cracks at the end can be suppressed. Further, since the edges facing each other on both ends of the slit 20 are gradually approached toward the ends and the width is narrowed, the edges 22 facing each other on both ends of the slit 20 are in close contact with each other. This facilitates the process, and the edge portion 22 of the slit 20 is partially in contact with each other, and the deformation caused by the concentration of the load on the abutted portion can be suppressed.

Further, according to the medical tubular member 10 according to the present embodiment, since the slit 20 exists on the straight line B substantially parallel to the axis X direction at any position in the circumferential direction, at any position in the axis X direction. However, it can be smoothly bent in any direction intersecting the X direction of the axis, and high flexibility can be obtained.

Further, according to the medical tubular member 10 according to the present embodiment, the slits 20 are arranged so as to be spirally connected in the circumferential direction. As a result, the degree of freedom of bending can be increased, and the bending can be performed more smoothly in all directions intersecting the X direction of the axis.

Further, according to the medical tubular member 10 according to the present embodiment, for example, the member to be inserted to be inserted into a tubular tissue such as a blood vessel can be provided on the front side in the insertion direction and the rear side in the insertion direction, respectively. In this case, even if the tubular tissue is curved, the medical tubular member 10 of the inserted member to be inserted into the tubular tissue can be smoothly bent, and the inserted member is smoothly conveyed to a predetermined position in the tubular tissue. be able to.

(Foreign matter removal device, foreign matter removal catheter)
Next, a foreign matter removing device and a foreign matter removing catheter provided with the medical tubular member 10 will be described.
FIG. 6 is a schematic configuration diagram illustrating a foreign matter removing catheter according to the present embodiment. 7A and 7B are views showing the internal structure of the foreign matter removing catheter according to the present embodiment, FIG. 7A is a cross-sectional view when the retriever is expanded, and FIG. 7B is a cross-sectional view when the retriever is contracted. Is.

As shown in FIG. 6, the foreign matter removing catheter 50 includes a catheter main body 60, a foreign matter removing device 100 arranged at a distal portion of the catheter main body 60, and an operation unit 70 arranged at a proximal portion of the catheter main body 60. And.

In this specification, the "distal portion" refers to the region on the end side farther from the user of the foreign matter removing catheter 50, and the "proximal portion" refers to the use of the foreign matter removing catheter 50. Refers to the area on the end side (hand side) that is closer to the person.

The foreign matter removing catheter 50 is, for example, a thrombus removing catheter for removing or collecting a foreign matter such as a thrombus or an embolus generated in a blood vessel with the foreign matter removing device 100.

The foreign matter removing device 100 includes the tubular member 10 according to the present embodiment described above, and the retriever 120 provided on the tubular member 10. The retriever 120 is a member to be inserted that is inserted into the tubular tissue and is capable of expanding and contracting.

Although not illustrated, the tubular member 10 and retriever 120 can be formed by laser machining a single metal pipe (eg, a pipe made of a Ni—Ti alloy). In this case, the tubular member 10 and the retriever 120 can be integrally formed.

The tubular member 10 has a distal tubular member 10F on the distal side with respect to the retriever 120 and a proximal tubular member 10N on the proximal side with respect to the retriever 120.

As shown in FIGS. 7 (a) and 7 (b), the catheter body 60 includes a first tube 62 extending from the distal portion to the proximal portion of the catheter body 60, a foreign matter removing device 100, and an operation unit 70. It has a second tube 64 to be connected. The first tube 62 is provided with a lumen for a guide wire for inserting the guide wire.

The distal end of the distal tubular member 10F constituting the foreign matter removing device 100 is connected to the outer peripheral surface of the distal portion of the first tube 62. The proximal end of the proximal tubular member 10N constituting the foreign matter removing device 100 is connected to the inner peripheral surface of the distal portion of the second tube 64. The inner diameter of the second tube 64 is set to be larger than the outer diameter of the first tube 62, and a gap having a predetermined dimension is provided between the first tube 62 and the second tube 64.

Both the first tube 62 and the second tube 64 are made of a flexible material. Examples of the flexible material include a synthetic resin (elastomer), a resin compound in which another material is mixed with the synthetic resin, a multilayer structure composed of multiple layers of the synthetic resin, or a composite of the synthetic resin and a metal wire. Etc. can be preferably used.

The operation unit 70 has, for example, a stick-shaped (rod-shaped) operation unit main body 72, a slider 76 installed on the side surface of the operation unit main body 72, and a liquid filling port 78 provided on the side surface of the operation unit main body 72.

An elongated hole 74 extending along the longitudinal direction (tube axis direction) is provided on the side surface of the operation unit main body 72. The slider 76 is connected to the first tube 62 via an elongated hole 74, and is configured to be able to translate along the longitudinal direction (tube axial direction).

The liquid filling port 78 communicates with the internal lumen of the second tube 64 (the gap between the first tube 62 and the second tube 64), and the inside of the catheter body 60 via the liquid filling port 78, for example, physiological saline or the like. It is configured so that it can be filled with liquid. Although the description by illustration is omitted, the open end of the liquid filling port 78 is liquid-tightly closed by a sealing member such as a cap or a valve body made of silicon rubber or the like.

Here, the movement of the foreign matter removing device 100 when the slider 76 is moved will be described with reference to FIGS. 7 (a) and 7 (b).

First, when the slider 76 is moved in the direction of the arrow X1 in the state shown in FIG. 7A, the first tube 62 connected to the slider 76 also moves in the X1 direction. At this time, the connection position between the first tube 62 and the foreign matter removing device 100 moves in the X1 direction, but the connection position between the first tube 62 and the second tube 64 does not change. That is, as a result of the first tube 62 moving relative to the second tube 64 in the X1 direction, the retriever 120 contracts (see FIG. 7B).

On the other hand, when the slider 76 is moved in the arrow X2 direction in the state shown in FIG. 7B, the first tube 62 connected to the slider 76 also moves in the X2 direction. At this time, the connection position between the first tube 62 and the foreign matter removing device 100 moves in the X2 direction, but the connection position between the first tube 62 and the second tube 64 does not change. That is, as a result of the first tube 62 moving relative to the second tube 64 in the X2 direction, the retriever 120 expands (see FIG. 7A).

That is, the expansion / contraction of the retriever 120 can be operated by moving the slider 74 in parallel along the longitudinal direction (tube axis direction).

Next, an example of how to use the foreign matter removing catheter 50 will be described with reference to FIG.

8A and 8B are views for explaining how to use the foreign matter removing catheter, and FIGS. 8A to 8F are schematic cross-sectional views of foreign matter removing positions in the tubular tissue, respectively. 8 (a) to 8 (f) schematically show the shapes and the like of each member constituting the foreign matter removing catheter 50 in order to facilitate understanding of the invention.

First, as shown in FIG. 8A, the guiding catheter GC is inserted into the blood vessel along the guide wire W with the guide wire W passed through the blood vessel, and the target site (foreign substance) at a predetermined position is inserted. The foreign matter removing catheter 50 is delivered to just before the site where CL is present).

Next, as shown in FIG. 8B, the foreign matter removing catheter 50 is sent out from the guiding catheter GC, the foreign matter CL is penetrated in a state where the retriever 120 is contracted, and the retriever 120 is distal to the target site. Place in.

Next, as shown in FIG. 8C, with the retriever 120 expanded, the foreign matter removing catheter 50 is pulled toward the hand side, and the foreign matter CL is entangled with the retriever 120 (see FIG. 8D). .. In order to entangle the foreign body CL with the retriever 120, for example, the retriever 120 may be rotated around the tube axis at the target site, the retriever 120 may be advanced / retracted at the target site, or the retriever 120 may be moved forward / backward at the target site. May expand / contract.

Then, as shown in FIG. 8E, the retriever 120 is contracted while the foreign matter CL is entwined, and the retriever 120 (foreign matter removing catheter 50) is pulled into the guiding catheter GC (see FIG. 8F). ). After that, by removing the foreign matter removing catheter 50 from the inside of the guiding catheter GC, the foreign matter CL can be taken out of the body percutaneously.

As described above, the foreign matter removing device 100 according to the present embodiment not only obtains the same effect as the medical tubular member 10 described above, but also removes or recovers foreign matter in a tubular tissue such as a blood vessel. The foreign matter removing device 100 can be smoothly transported to the required predetermined position. Thereby, the foreign matter in the tubular tissue can be easily removed or recovered.

Further, according to the foreign matter removing catheter 50 according to the present embodiment, not only the same effect as the medical tubular member 10 described above can be obtained, but also the foreign matter removing device 100 can be obtained substantially in the same manner as the foreign matter removing device 100 described above. It can be smoothly inserted into a predetermined position where foreign matter in a tubular tissue such as a blood vessel needs to be removed or recovered, and the foreign matter in the tubular tissue can be easily removed or recovered.

The present invention is not limited to those exemplified in the above embodiments, and can be implemented in various aspects without departing from the gist of the present invention. For example, the following modifications can be made. be.

In the above embodiment, the slits 20 of the tubular member 10 are formed so as to be spirally connected in the circumferential direction at a slight inclination with respect to the straight line A orthogonal to the axis X, and the slits 20 are spirally connected in the circumferential direction. Although the case where the interslit region portion 24 between the slits is arranged in a spiral shape has been described as an example, the present invention is not limited to this.
For example, as shown in FIG. 9, the slits 20 are formed so as to be continuous in the circumferential direction along a straight line A orthogonal to the axis X at a plurality of locations spaced apart in the axial direction X direction, and the slits 20 are continuous in the circumferential direction. The interslit region portions 24 between the slits may be arranged alternately in the axis X direction. In this case as well, the degree of freedom of bending can be increased, and the bending can be performed more smoothly in any direction intersecting the axis X direction.

The spacing (repeating pitch) between adjacent slits 20 in the plurality of slits 20 may be different depending on, for example, the axial position of the tubular member 10. Specifically, for example, the flexibility may be changed by changing the pitch between the portion on the distal end side of the tubular member 10 and the portion on the proximal end side opposite to the distal end side, or from the proximal end side to the distal end. By gradually changing the pitch toward the side, it may be easier to bend toward the tip side.

As for the shape of the slit 20, for example, as shown in FIG. 10, in the central region 20A, the linear edge portions 22 are arranged in parallel, and in the both end regions 20B, the slits are linear from the central side to the end portions. The edges 22 of the above may be in a shape in which the edges 22 are gradually brought closer to each other and the width is gradually narrowed.
Further, in the slit 20, even if the hole 21 is not continuous with the portion of the edge 22 facing each other on both ends in the extending direction, which is gradually approached toward the end and narrowed in width. good. For example, although not shown, a parallel portion having a constant width is formed continuously to a portion of the edge portion 22 that is gradually approached and narrowed in width, and a hole portion 21 is continuously formed in the parallel portion. It may be formed.

Further, the material, shape, and the like of the tubular member 10 illustrated in the above embodiment are merely examples and are not limited to this, and can be arbitrarily changed as appropriate. That is, the case where the tubular member 10 is made of a metal material has been described as an example, but the present invention is not limited to this, and for example, resin or wood may be used. Further, the case where the cross-sectional shape of the tubular member 10 is circular has been described as an example, but the present invention is not limited to this, and may be, for example, an elliptical shape or a polygonal shape. May be good.

Further, in the above embodiment, the case where the holes 21 at both ends of the slit 20 have a circular shape has been described as an example, but the present invention is not limited to this, and the slit 20 has, for example, an elliptical shape. May be good.

Further, in the above embodiment, the case where the tubular member 10 and the retriever 120 are integrally formed has been described as an example, but the present invention is not limited to this, and the tubular member 10 and the retriever 120 are used. After forming each as a separate body, the tubular member 10 and the retriever 120 may be joined by means such as adhesion or welding.

Further, in the above embodiment, the case where the tubular tissue to be used is a blood vessel has been illustrated and described, but the present invention is not limited thereto. For example, a tubular member 10 inserted inside another tubular tissue such as a digestive tract or a bile duct, a foreign substance removing device 100 for removing or recovering a foreign substance generated inside another tubular tissue such as the digestive tract or the bile duct. The present invention can also be applied to the foreign matter removing catheter 50.

(Evaluation test)
Various evaluation tests were performed on various tubular members in which the slits were arranged so as to be spirally connected and the interslit region between the ends of the slits was arranged spirally.

(1) Evaluation Sample The tubular members of Examples 1 to 3 and Comparative Example 1 described below in which various slits were formed in a pipe made of a Ni—Ti alloy having an outer diameter of 1.75 mm and an inner diameter of 1.45 mm were evaluated.
The tubular members of Examples 1 to 3 are formed with slits having holes at both ends, and the edges facing each other on both ends in the extending direction are gradually brought closer toward the ends to narrow the width. ing. The diameter of the hole is 0.08 mm in Example 1, 0.14 mm in Example 2, and 0.20 mm in Example 3.
The tubular member of Comparative Example 1 is formed with straight slits having no holes at both ends.

(2) Test contents (2-1) Flexibility test A tubular member is supported at intervals of 30 mm, a load is applied to the center of the tubular member, and the load is pushed in by 2 mm, and the load is measured. The measurement is performed three times for each tubular member, and the average value is calculated.
(2-2) Bending test The bent tubular member is sandwiched between two opposing flat plates, the distance between the flat plates is shortened, and the radius of curvature of the bent portion at the time of breaking of the tubular member is measured. The measurement is performed three times for each tubular member, and the average value is calculated.
(2-3) Tensile test Each tubular member is pulled by a tensile tester at a tensile speed of 10 mm / min, and the tensile strength until fracture is measured. The measurement is performed three times for each tubular member, and the average value is calculated.

(3) Evaluation results Table 1 shows the results of each evaluation test.

(3-1) Flexibility test The average load when pushing each tubular member was 1.37N in Example 1, 1.14N in Example 2, 0.80N in Example 3, and 1. It became 68N. As described above, it was confirmed that Examples 1 to 3 having holes at both ends of the slit require less force for bending and improve flexibility as compared with Comparative Example 1 having holes at both ends of the slit. .. It was also confirmed that the larger the diameter of the hole, the more it contributes to the improvement of flexibility.
(3-2) Bending test The average radius of curvature of each tubular member was 2.08 mm in Example 1 and 3.53 mm in Comparative Example 1, and no fracture occurred in Examples 2 and 3. By providing holes at both ends of the slit in this way, the radius of curvature that breaks due to bending becomes smaller as in Example 1 as compared with Comparative Example 1 in which there are no holes at both ends of the slit. It was confirmed that when the diameter of the hole is 0.14 mm or more as in 2 and 3, breakage due to bending does not occur.
(3-3) Tensile Test The average tensile strength of each tubular member was 40.9N in Example 1, 38.0N in Example 2, 27.3N in Example 3, and 46.7N in Comparative Example 1. .. It was confirmed that in Examples 1 to 3 having holes at both ends of the slit, sufficient tensile strength was obtained, although the tensile strength was slightly lower than that of Comparative Example 1 having no holes at both ends of the slit.

Based on the results of the above evaluation test, by providing holes with a diameter of 0.08 mm or more and 0.20 mm or less at both ends of the slit formed in the tubular member, flexibility is improved while suppressing breakage and deformation in the slit. In particular, it was confirmed that by providing holes with a diameter of 0.14 mm at both ends of the slit, the effect of suppressing breakage and deformation in the slit of the tubular member and the improvement of flexibility can be further enhanced. did it.

10: Medical tubular member 11: Tube wall 20: Slit 21: Hole 22: Edge 24: Interslit region 50: Foreign matter removing catheter 60: Catheter body 70: Operating unit 100: Foreign matter removing device 120: Retriever ( Inserted member)
B: Straight line CL: Foreign matter X: Axis

Claims (6)

A tubular medical tubular member that is inserted into a tubular tissue.
The inserted member inserted into the tubular tissue and expandable and contractible in the radial direction substantially orthogonal to the axial direction is integrally formed on at least one of the front side in the insertion direction and the rear side in the insertion direction.
A plurality of slits are formed through the tube wall of the medical tubular member and along the direction diagonally intersecting the axial direction.
Each of the plurality of slits
The edges facing each other are gradually brought closer to each other toward both ends in the extending direction of the slit, and the width is narrowed.
A medical tubular member characterized in that both ends thereof bulge so as to form a round hole. The medical tubular member according to claim 1, wherein the slit exists on a straight line substantially parallel to the axial direction at any position in the circumferential direction. The medical tubular member according to claim 1 or 2, wherein the plurality of slits are arranged so as to be spirally connected in the circumferential direction. The medical tubular member according to claim 1 or 2, wherein the plurality of slits are arranged so as to be adjacent to each other in the axial direction so as to be displaced in the circumferential direction. A foreign matter removing device configured to remove or recover foreign matter in a tubular tissue.
A member to be inserted that is inserted into the tubular tissue and can be expanded or contracted in the radial direction substantially orthogonal to the axial direction.
Wherein among the insertion direction front side and the insertion direction rear side of the insertion member is formed integrally on at least one, and a cylindrical tubular member which is inserted into the tubular tissue,
The tubular member is formed with a plurality of slits penetrating the tube wall and along a direction diagonally intersecting the axial direction.
Each of the plurality of slits
The edges facing each other are gradually brought closer to each other toward both ends in the extending direction of the slit, and the width is narrowed.
A foreign matter removing device characterized in that both ends are bulged so as to form a round hole shape. A foreign matter removal catheter for removing or recovering foreign matter in a tubular tissue.
Catheter body and
A foreign body removing device located at the distal portion of the catheter body and configured to remove or recover foreign body in the tubular tissue.
The foreign matter removing device is
A member to be inserted that is inserted into the tubular tissue and can be expanded or contracted in the radial direction substantially orthogonal to the axial direction.
Wherein among the insertion direction front side and the insertion direction rear side of the insertion member is formed integrally on at least one, and a cylindrical tubular member which is inserted into the tubular tissue,
The tubular member is formed with a plurality of slits penetrating the tube wall and along a direction diagonally intersecting the axial direction.
Each of the plurality of slits
The edges facing each other are gradually brought closer to each other toward both ends in the extending direction of the slit, and the width is narrowed.
A foreign matter removing catheter characterized in that both ends are bulged so as to form a round hole shape.

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