JP6975226B2 - Mixing aids and syringe system - Google Patents

Description

The present invention relates to a mixing aid and a syringe system used when mixing drugs in two syringes.

Conventionally, a syringe kit for mixing two drugs for mixing drugs in two syringes is known (see, for example, Japanese Patent Application Laid-Open No. 2013-132349). In the use of this type of syringe kit, in order to mix the drugs in the two syringes, the barrels of the two syringes are connected to each other and the pusher of one syringe is pushed into the barrel of the one syringe. Transfer the drug from the other syringe to the barrel of the other syringe.

In the conventional syringe kit for mixing two drugs, when transferring the drug from one barrel to the other barrel, the drug cannot be transferred due to the resistance of the gasket in the other barrel, or the transfer takes time. There is. In particular, in the case of a powder having a large amount of air in the syringe, the buffer due to the compression of air is large and the migration takes time.

The present invention has been made in consideration of such a problem, and an object of the present invention is to provide a mixing aid and a syringe system capable of shortening the mixing time of a drug using a syringe kit.

In order to achieve the above object, the present invention is a mixing aid that can be attached to a syringe kit including two syringes having tips that can be connected to each other for mixing drugs. Each has a barrel with a radial outwardly projecting finger grip at the base, a gasket slidably disposed within the barrel, and a pusher base end connected to the gasket and at the base. The finger grip is formed in a non-circular shape having a minor axis and a major axis, and the mixing aid is such that the two syringes are attached to each other. A first mounting portion to which one of the pusher base ends of the connected syringe kit can be mounted, and a second mounting portion to which the other pusher base end of the connected syringe kit can be mounted. The mounting portion is provided with a rod-shaped connecting portion that connects the first mounting portion and the second mounting portion, and the width of the connecting portion in the direction perpendicular to the longitudinal direction of the mixing assisting tool is the finger. The finger grip is connected to the first mounting portion and the second mounting portion, with one and the other syringe base ends mounted on the first mounting portion and the second mounting portion, which are smaller than the length along the long axis of the grip. It is characterized in that it protrudes outward from the portion.

According to the mixing aid having the above configuration, the pushers of the two syringes are connected to each other by the mixing aid, so that when one pusher is pushed toward the tip, the other pusher is simultaneously pushed. Is pulled toward the proximal end. As a result, the transfer of the drug is smoothly performed, and the mixing time can be shortened. Further, even when air is contained in the syringe, air is not compressed during mixing, and smooth mixing is possible. Further, since the mixing can be performed by pushing the pusher as in the case where the mixing assisting tool is not used, it is possible to perform the mixing with the same operation feeling.

The connecting portion has two connecting members extending so as to face each other, and one end side of each of the two connecting members is connected to the first mounting portion, and each of the two connecting members is connected to the first mounting portion. The other end side is connected to the second mounting portion, and the syringe kit is arranged between the two connecting members in a state where the syringe kit in the connected state is mounted on the mixing aid. You may.

With this configuration, deformation of the connecting portion during the mixing operation is suppressed, so that the transfer of the drug can be performed more smoothly.

The first mounting portion and the second mounting portion have a finger rest portion that supports the base end surface of the pusher base end portion and is pressed by a finger, and the longitudinal length of the mixing assist tool of the finger rest portion. The width in the direction perpendicular to the direction may be larger than the diameter of the pusher base end portion and smaller than the length along the long axis of the finger grip.

With this configuration, since the finger pad has an appropriate size, it is easy to put a finger on the finger pad and push the pusher when performing the mixing operation.

The mixing aid may be deformable into a first form in which the syringe kit in a connected state can be attached and a second form in which the total length is shorter than that of the first form.

With this configuration, the mixing aid can be stored compactly in the second form before use. Further, after use, it can be transformed from the first form to the second form and disposed of compactly.

The connecting portion has a first member having the first mounting portion and a second member having the second mounting portion, and the first member and the second member rotate with each other via a hinge portion. It may be movably connected.

Thereby, it is possible to realize a mixing aid that can be transformed into the first form and the second form with a simple and economical configuration.

Further, the present invention is a mixture in which a syringe kit including two syringes whose tips can be connected to each other for mixing drugs and the syringe kit in a connected state in which the two syringes are connected to each other can be attached. A syringe system comprising an assistive device, each of which is connected to a barrel having a finger grip at its base, a gasket slidably disposed within the barrel, and the gasket. The finger grip is formed in a non-circular shape having a short axis and a long axis, and has a syringe base end portion at the base end and a pusher protruding from the base end opening of the barrel toward the base end. The mixing aid is mounted by a first mounting portion to which one of the pusher base ends of the syringe kit in the connected state can be mounted and the pusher base end of the other of the syringe kit in the connected state. A possible second mounting portion and a rod-shaped connecting portion that connects the first mounting portion and the second mounting portion are provided, and the width of the connecting portion in a direction perpendicular to the longitudinal direction of the mixing assisting tool. Is smaller than the length of the pusher base end portion along the long axis, and one and the other pusher base end portions are mounted on the first mounting portion and the second mounting portion. The finger grip is characterized in that it projects outward from the connecting portion.

In the syringe system, the connecting portion has two connecting members extending so as to face each other, and one end side of each of the two connecting members is connected to the first mounting portion. The other end of each of the connecting members is connected to the second mounting portion, and the syringe kit in the connected state is mounted on the mixing aid, and the syringe kit is the two connecting members. It may be placed between.

With this configuration, deformation of the connecting portion during the mixing operation is suppressed, so that the transfer of the drug can be performed more smoothly.

In the syringe system, the first mounting portion and the second mounting portion have a finger contact portion that supports the proximal end surface of the pusher base end portion and is pressed by a finger, and the finger contact portion of the finger contact portion. The width in the direction perpendicular to the longitudinal direction of the mixing aid may be larger than the diameter of the push base end portion and smaller than the length along the long axis of the finger grip.

With this configuration, since the finger pad has an appropriate size, it is easy to put a finger on the finger pad and push the pusher when performing the mixing operation.

In the syringe system, the mixing aid may be deformable into a first form in which the syringe kit in a connected state can be attached and a second form in which the total length is shorter than that of the first form.

With this configuration, the mixing aid can be stored compactly in the second form before use. Further, after use, it can be transformed from the first form to the second form and disposed of compactly.

In the syringe system, the connecting portion has a first member having the first mounting portion and a second member having the second mounting portion, and the first member and the second member are hinged portions. They may be rotatably connected to each other via.

Thereby, it is possible to realize a mixing aid that can be transformed into the first form and the second form with a simple and economical configuration.

In the syringe system, air may be contained in the filling space formed in the barrel of at least one of the two syringes on the distal end side of the gasket in the initial state of the syringe kit.

With this configuration, even if the total length of the syringe kit with the two syringes connected to each other and the length between the first mounting part and the second mounting part are different, the pusher is axially pushed by the amount of air. Since it can be moved, the syringe kit can be attached to the mixing aid without forcibly deforming the connecting portion.

In the syringe system, a screwing protrusion that can be screwed into each other is provided at the tip of the barrel of the two syringes, and a flange portion that protrudes outward in the radial direction is provided at the base end of the barrel. The finger grip provided may be a grip member rotatably mounted on the flange portion about the axis of the barrel.

With this configuration, the finger grip can be easily and surely protruded to the outside of the connecting portion regardless of the screwed state of the screwing protrusion.

According to the mixing aid and the syringe system of the present invention, it is possible to shorten the mixing time of the drug using the syringe kit.

It is a perspective view of the syringe system which concerns on 1st Embodiment of this invention. It is a perspective view of a syringe kit (before connection). It is a top view of the syringe system shown in FIG. FIG. 3 is a cross-sectional view taken along the line IV-IV in FIG. It is a perspective view of a syringe kit (after connection). It is explanatory drawing when the length of a syringe kit and a mixing aid is different. It is a perspective view of the syringe system which concerns on 2nd Embodiment of this invention. It is a perspective view of the mixing aid of the syringe system shown in FIG. 7 in a bent state.

Hereinafter, the mixing aid and the syringe system according to the present invention will be described with reference to suitable embodiments with reference to the accompanying drawings. In the second embodiment, the same or similar elements as those in the first embodiment are designated by the same reference numerals, and detailed description thereof will be omitted.

[First Embodiment]
The syringe system 10 according to the first embodiment shown in FIG. 1 is a device for mixing the filling in one barrel and the filling in the other barrel. The syringe system 10 can be equipped with a syringe kit 12 having two syringes whose tips can be connected to each other for mixing the drug M, and a syringe kit 12 in a connected state in which the two syringes are connected to each other. A mixing aid 14 is provided. FIG. 1 shows a state in which the syringe kit 12 is attached to the mixing aid 14.

The syringe kit 12 includes a male syringe 16 and a female syringe 18 that can be screwed and connected to each other. Both the male syringe 16 and the female syringe 18 are configured as prefilled syringes prefilled with contents such as drugs.

In the following description, regarding the male syringe 16, the side connected to the female syringe 18 or its direction is referred to as "tip portion" or "tip direction", and the opposite side or opposite direction is referred to as "base end portion" or "base end portion". It is called "base direction". Further, regarding the female syringe 18, the side connected to the male syringe 16 or its direction is referred to as "tip portion" or "tip direction", and the opposite side or opposite direction is referred to as "base end portion" or "base end direction". Call.

As shown in FIGS. 2 and 4, the male syringe 16 is connected to the male syringe barrel 20 made of a hollow body, the gasket 22 slidably inserted into the male syringe barrel 20, and the gasket 22. A pusher 24A and a drug M filled in a filling space 21 formed by a male syringe barrel 20 and a gasket 22 are provided. Hereinafter, the "male syringe barrel 20" is abbreviated as "male barrel 20".

The male barrel 20 has a substantially cylindrical shape and a barrel body portion 20a having a base end opening formed at the base end, a nozzle 20b provided at the tip of the barrel body portion 20a, and a lock provided on the outside of the nozzle 20b. It has an adapter 20c, a flange portion 20f protruding radially outward from the base end of the barrel body portion 20a, and a finger grip 26A provided at the base end portion of the barrel body portion 20a. The barrel body portion 20a, the nozzle 20b, the lock adapter 20c, and the flange portion 20f are integrally molded. The male barrel body is composed of a barrel body portion 20a, a nozzle 20b, a lock adapter 20c, and a flange portion 20f.

The nozzle 20b has a diameter reduced from the center of the tip of the barrel body 20a with respect to the barrel body 20a and extends toward the tip. The nozzle 20b has a passage 20g (see FIG. 4) that penetrates in the axial direction and communicates with the lumen (filling space 21) of the barrel body 20a.

The nozzle 20b is configured as an male lure having a circular outer shape in cross section and having a tapered outer peripheral surface 20bs whose outer diameter decreases toward the tip end. The nozzle 20b can be fitted to the tubular portion 40b (messuler) described later of the female syringe 18.

As shown in FIG. 2, the lock adapter 20c has a substantially hollow cylindrical shape extending from the tip of the barrel body 20a toward the tip and concentrically surrounding the nozzle 20b. A screw 20e is formed on the inner peripheral surface of the lock adapter 20c.

The flange portion 20f has a non-circular shape in which portions of the outer peripheral portion of the circle opposite to each other are cut in a straight line.

The gasket 22 is inserted into the barrel body 20a via a base opening that opens at the base end of the barrel body 20a. The base end side of the barrel body 20a is hermetically sealed by the gasket 22. The gasket 22 is made of an elastic material such as a rubber material. The outer peripheral portion of the gasket 22 is in close contact with the inner peripheral surface of the barrel body portion 20a and is slidably arranged in the barrel body portion 20a.

A gasket 22 is connected to the tip of the pusher 24A. Specifically, the pusher 24A has a shaft portion 28A whose tip end is connected to the gasket 22, and a pusher base end portion 30A provided at the base end of the shaft portion 28A. The pusher base end portion 30A is formed in a flange shape protruding radially outward from the base end of the shaft portion 28A. When the user presses the pusher 24A in the axial direction (tip direction or base end direction), the gasket 22 slides in the barrel body portion 20a in the axial direction. The pusher 24A may be connected to the gasket 22 when the male syringe 16 is used.

The finger grip 26A is a grip member 27A rotatably mounted on the flange portion 20f about the axis of the male barrel 20. The grip member 27A has a base portion 32 mounted on the base end portion of the male barrel 20 and a pair of finger hook portions 34 protruding in opposite directions to each other, and has a short axis when viewed from the axial direction of the male barrel 20. It is formed in a non-circular shape with a long axis. The finger grip 26A has a U-shaped flange mounting groove 36. By inserting (fitting) the flange portion 20f into the flange mounting groove 36, the male barrel 20 and the grip member 27A are fixed so as not to be relatively movable in the axial direction.

The drug M is a powdered drug or a freeze-dried drug as long as it is dissolved, diluted and mixed with a medical liquid ML (specifically, a solution such as physiological saline) filled in the female syringe 18. , Solid drug, liquid drug, etc. may be used. Examples of such drug M include protein preparations, peptide preparations, antitumor agents, vitamin agents (multivitamin agents), various amino acids, antithrombotic agents such as heparin, insulin, antibiotics, painkillers, cardiotonic agents, and intravenous drugs. Injection anesthetics, medical drugs, antithrombotic agents, ulcer therapeutic agents, corticosteroid agents, arrhythmic agents and the like can be mentioned.

In the initial state of the male syringe 16, a cap (not shown) is attached to the nozzle 20b, and the tip opening 20b1 of the nozzle 20b is sealed by this cap. This cap is removed from the nozzle 20b when the male syringe 16 is used (when the syringe kit 12 is used).

The female syringe 18 includes a female syringe barrel 40 made of a hollow body, a gasket 42 slidably inserted into the female syringe barrel 40, a pusher 24B connected to the gasket 42, and a female syringe barrel 40. A medical liquid ML filled in the filling space 43 formed by the gasket 42 and the gasket 42 is provided. Hereinafter, the "barrel 40 for female syringe" is abbreviated as "female barrel 40".

The female barrel 40 has a substantially cylindrical shape and a base end opening formed at the base end, a barrel body portion 40a protruding from the tip end of the barrel body portion 40a toward the tip end, and a base of the barrel body portion 40a. It has a flange portion 40f formed so as to project radially outward from the end, and a finger grip 26B attached to the base end portion of the barrel body portion 40a. The female barrel body is composed of the barrel body portion 40a, the cylinder portion 40b, and the flange portion 40f.

The cylinder portion 40b extends from the tip end of the barrel body portion 40a toward the tip end. The tubular portion 40b has a passage that penetrates in the axial direction and communicates with the lumen (filling space 43) of the barrel body portion 40a. The tubular portion 40b is configured as a messuler having a tapered inner peripheral surface 40bs (see also FIG. 4) whose outer diameter increases toward the tip end.

The outer peripheral portion of the tip of the tubular portion 40b is provided with two protrusions 40d protruding outward (diameterally outward) opposite to each other with respect to the axis (center line) of the tubular portion 40b. The two protrusions 40d can be screwed with the screw 20e provided on the lock adapter 20c of the male barrel 20.

The flange portion 40f has a non-circular shape in which portions of the outer peripheral portion of the circle opposite to each other are cut in a straight line.

In FIG. 2, the gasket 42 is inserted into the barrel body 40a via the base opening that opens at the base end of the barrel body 40a. The base end side of the barrel body 40a is hermetically sealed by the gasket 42. The gasket 42 is made of an elastic material such as a rubber material. The outer peripheral portion of the gasket 42 is in close contact with the inner peripheral surface of the barrel body portion 40a and is slidably arranged in the barrel body portion 40a.

A gasket 42 is connected to the tip of the pusher 24B. Specifically, the pusher 24B has a shaft portion 28B whose tip end is connected to the gasket 42, and a pusher base end portion 30B provided at the base end of the shaft portion 28B. The pusher base end portion 30B is formed in a flange shape protruding radially outward from the base end of the shaft portion 28B. When the user presses the pusher 24B in the axial direction (tip direction or base end direction), the gasket 42 slides in the barrel body portion 40a in the axial direction. The pusher 24B may be connected to the gasket 42 when using the female syringe 18.

The finger grip 26B is a grip member 27B rotatably mounted on the flange portion 40f about the axis of the female barrel 40. The grip member 27B has a base portion 46 mounted on the base end portion of the female barrel 40 and a pair of finger hook portions 48 protruding from the base portion 46 in opposite directions, and is viewed from the axial direction of the female barrel 40. , Formed in a non-circular shape with a minor axis and a major axis. The finger grip 26A has a U-shaped flange mounting groove 50. By inserting (fitting) the flange portion 40f into the flange mounting groove 50, the female barrel 40 and the grip member 27B are fixed so as not to be relatively movable in the axial direction.

In the initial state of the female syringe 18, a cap (not shown) is attached to the tubular portion 40b, and the tip opening of the tubular portion 40b is sealed by this cap. This cap is removed from the tubular portion 40b when the female syringe 18 is used (when the syringe kit 12 is used).

The medical liquid ML is a liquid capable of dissolving, diluting or mixing the drug M in the male syringe 16. Such a medical liquid ML may be a drug solution such as physiological saline, a drug diluent, a drug mixture, or a drug solution containing a drug (for example, a vitamin preparation or minerals). The medical liquid ML is not previously filled in the female syringe 18 as in the present embodiment, but may be sucked from a vial or the like into an empty female syringe 18 as needed.

The male barrel 20 and the female barrel 40 are made of a transparent hard material. Examples of the constituent materials of the male barrel 20 and the female barrel 40 include cyclic polyolefin, polypropylene, polycarbonate and the like.

In the initial state of the syringe kit 12, air is contained in the filling space formed on the tip side of the gasket in at least one of the barrels of the male syringe 16 and the female syringe 18.

As shown in FIGS. 1, 3 and 4, the mixing aid 14 has a first mounting portion 54A to which one pusher base end portion 30A of the connected syringe kit 12 can be mounted and a syringe kit in the connected state. A second mounting portion 54B to which the other pusher base end portion 30B of 12 can be mounted and a rod-shaped connecting portion 58 connecting the first mounting portion 54A and the second mounting portion 54B are provided. The connecting portion 58 has two connecting members 60 extending so as to face each other. The first mounting portion 54A, the second mounting portion 54B, and the connecting portion 58 are integrally molded by, for example, injection molding or the like.

In FIGS. 1, 3 and 4, the pusher base end 30A of the male syringe 16 is mounted on the first mounting portion 54A, and the pusher base end 30B of the female syringe 18 is mounted on the second mounting portion 54B. The state is shown. The pusher base end 30A of the male syringe 16 may be mounted on the second mounting portion 54B, and the pusher base end 30B of the female syringe 18 may be mounted on the first mounting portion 54A.

The first mounting portion 54A and the second mounting portion 54B face each other at intervals in the longitudinal direction of the mixing assist tool 14. Since the first mounting portion 54A and the second mounting portion 54B are configured to have the same shape, the configuration of the first mounting portion 54A will be typically described below.

As shown in FIGS. 1 and 4, the first mounting portion 54A supports the base end surface of the pusher base end portion 30A and is pushed between the finger contact portion 62 and the finger contact portion 62 pressed by a finger. It has a holding portion 64 that holds the child base end portion 30A. The finger contact portion 62 has a flange contact surface 62a that abuts on the base end surface of the pusher base end portion 30A and a finger contact surface 62b that is formed on the opposite side of the flange contact surface 62a and is pressed by a finger. It is provided.

In the first embodiment, the finger rest portion 62 is formed in the shape of a circular plate. As shown in FIG. 3, the width Wf of the finger rest portion 62 in the direction perpendicular to the longitudinal direction of the mixing aid 14 is larger than the diameter D (see FIG. 2) of the pusher base end portion 30A, and the finger grip. It is smaller than the length La along the long axis of 26A.

As shown in FIGS. 1 and 4, the sandwiching portion 64 has a pair of engaging protrusions 64a protruding from the connecting portion 58 so as to face each other. A slit 64b (gap) is formed between the pair of engaging protrusions 64a. In the state where the syringe kit 12 is attached to the mixing aid 14, the shaft portion 28A of the pusher 24A is arranged (inserted) in the slit 64b. The width of the holding portion 64 is smaller than the width Wf of the finger rest portion 62.

As shown in FIGS. 1 and 3, the finger contact surface 62b of the finger contact portion 62 is provided with a locking projection 68 that can be engaged with the outer peripheral portion of the pusher base end portion 30A. When the flange of the pusher 24 is mounted on the first mounting portion 54A, the pusher base end portion 30A is between the finger contact portion 62 and the holding portion 64 from the side opposite to the side where the locking projection 68 is provided. Will be inserted into. At that time, the position of the pusher 24 with respect to the first mounting portion 54A is positioned at an appropriate position by the locking projection 68.

The two connecting members 60 constituting the connecting portion 58 extend in parallel and linearly between the first mounting portion 54A and the second mounting portion 54B. One end side of each of the two connecting members 60 is connected to the first mounting portion 54A. The other end of each of the two connecting members 60 is connected to the second mounting portion 54B.

When the connected syringe kit 12 is attached to the mixing aid 14, the syringe kit 12 is arranged between the two connecting members 60. That is, the mixing assist tool 14 has a rectangular frame shape by the two connecting members 60, the first mounting portion 54A and the second mounting portion 54B, and the syringe kit 12 is arranged inside the frame shape. It is configured.

As shown in FIG. 3, the width W of the connecting portion 58 in the direction perpendicular to the longitudinal direction of the mixing aid 14 is smaller than the lengths La and Lb along the long axis of the finger grips 26A and 26B. As a result, the finger grips 26A and 26B project outward from the connecting portion 58 in a state where one and the other pusher base end portions 30A and 30B are mounted on the first mounting portion 54A and the second mounting portion 54B. ..

The mixing aid 14 is made of a hard material. Examples of the constituent material of the mixing aid 14 include cyclic polyolefin, polypropylene, polycarbonate and the like. The mixing aid 14 may be made of a metal material.

Next, a method of using the syringe system 10 configured as described above will be described.

First, in the male syringe 16 and the female syringe 18 shown in FIG. 2, caps (not shown) are removed (opened) from the nozzle 20b of the male barrel 20 and the tubular portion 40b of the female barrel 40, respectively.

Next, as shown in FIG. 5, the male barrel 20 and the female barrel 40 are connected to each other. Specifically, the screw 20e (FIG. 2) of the lock adapter 20c and the protrusion 40d (FIG. 2) provided on the tubular portion 40b of the female barrel 40 are screwed together. Along with this screwing, the nozzle 20b (male lure) of the male barrel 20 is inserted into the tubular portion 40b (mess lure) of the female barrel 40. As a result, the tapered outer peripheral surface 20bs (FIG. 2) of the nozzle 20b is liquid-tightly fitted to the tapered inner peripheral surface 40bs (FIG. 2) of the tubular portion 40b.

Next, as shown in FIG. 1, the syringe kit 12 in which the male syringe 16 and the female syringe 18 are connected to each other is attached to the mixing aid 14. Specifically, the pusher base ends 30A and 30B of the male syringe 16 and the female syringe 18 are inserted into the first mounting portion 54A and the second mounting portion 54B, respectively, and mounted. As a result, the syringe kit 12 is arranged between the two connecting members 60 constituting the connecting portion 58, and the pair of finger hooking portions 34 and the pair of finger hooking portions 48 are placed between the two connecting members 60 with respect to the connecting portion 58. It will be in a state of protruding outward.

Next, the medical liquid ML and the drug M are mixed by performing a pumping operation using the pusher 24A of the male syringe 16 and the pusher 24B of the female syringe 18.

Specifically, while hooking a finger (for example, the index finger and the middle finger) on the grip member 27B of the female syringe 18, the finger contact portion 62 of the second mounting portion 54B is held with another finger (for example, the thumb) of the same hand. 1 By pushing toward the mounting portion 54A, the pusher 24B of the female syringe 18 is pressed toward the tip of the female syringe 18 via the second mounting portion 54B. As a result, the medical liquid ML is injected from the inside of the female barrel 40 into the male barrel 20, and the medical liquid ML and the drug M are mixed in the male barrel 20.

When pressing the second mounting portion 54B, the moving force (operating force) based on the pressing is transmitted to the first mounting portion 54A via the connecting portion 58. Therefore, at the same time as pressing the second mounting portion 54B, the pusher 24A of the male syringe 16 mounted on the first mounting portion 54A is pulled.

Next, while hooking a finger (for example, the index finger and the middle finger) on the grip member 27A of the male syringe 16, the finger contact portion 62 of the first mounting portion 54A is secondly mounted with another finger (for example, the thumb) of the same hand. By pushing toward the portion 54B side, the pusher 24A of the male syringe 16 is pressed toward the tip of the male syringe 16 via the first mounting portion 54A. As a result, the mixed liquid (a mixture of the medical liquid ML and the drug M) is injected from the inside of the male barrel 20 into the female barrel 40. Then, by repeating such movement of the mixed solution between the male barrel 20 and the female barrel 40 several times, the dissolution, dilution or mixing of the drug M is promoted, and the desired drug solution is adjusted.

When pressing the first mounting portion 54A, the moving force (operating force) based on the pressing is transmitted to the second mounting portion 54B via the connecting portion 58. Therefore, at the same time as pressing the first mounting portion 54A, the pusher 24 of the female syringe 18 mounted on the second mounting portion 54B is pulled.

In this case, the syringe system 10 according to the first embodiment has the following effects.

According to the syringe system 10, the pushers 24A and 24B of the two syringes 16 and 18 are connected to each other by the mixing assist tool 14, so that when one pusher is pushed toward the tip, the other pusher is pushed at the same time. An operation in which the child is pulled toward the proximal end occurs. As a result, the transfer of the drug is smoothly performed, and the mixing time can be shortened. Further, even when air is contained in the syringe, air is not compressed during mixing, and smooth mixing is possible. Further, since the mixing can be performed by pushing the pushers 24A and 24B in the same manner as when the mixing assist tool 14 is not used, it is possible to perform the mixing with the same operation feeling as in the conventional case.

The connecting portion 58 has two connecting members 60 extending so as to face each other. One end side of each of the two connecting members 60 is connected to the first mounting portion 54A. The other end of each of the two connecting members 60 is connected to the second mounting portion 54B. Then, the syringe kit 12 is arranged between the two connecting members 60 in a state where the connected syringe kit 12 is attached to the mixing aid 14. With this configuration, deformation of the connecting portion 58 during the mixing operation is suppressed, so that the transfer of the drug can be performed more smoothly.

Each of the first mounting portion 54A and the second mounting portion 54B has a finger contact portion 62 that supports the proximal end surface of the pusher proximal portion 30A and is pressed by a finger. The width W of the finger rest portion 62 is larger than the diameter D of the pusher base ends 30A and 30B, and smaller than the lengths La and Lb along the long axis of the finger grips 26A and 26B. With this configuration, since the finger rest portion 62 has an appropriate size, it is easy to put a finger on the finger rest portion 62 and push the pusher 24 when performing the mixing operation.

The finger grips 26A and 26B are grip members 27A and 27B rotatably mounted on the flange portions 26d and 40f about the axis of the barrel. With this configuration, the grip members 27A and 27B can be easily and surely protruded to the outside of the connecting portion 58 regardless of the screwed state of the screwing protrusions (screws 20e and 40d).

That is, the flange portions 26d and 40f of the male barrel 20 and the female barrel 40 have a non-circular shape having a major axis and a minor axis, and the flange portion 26d of the male barrel 20 and the female barrel 40 are in a state where the screw 20e and the protrusion 40d are completely screwed. The direction in the rotation direction may be different from that of the flange portion 40f. Even in such a case, since the grip members 27A and 27B can rotate with respect to the male barrel 20 and the female barrel 40, respectively, the syringe kit 12 is mixed with the mixing aid 14 after adjusting the rotation direction directions of the grip members 27A and 27B. By attaching the grip members 27A and 27B to the outside of the connecting portion 58, the grip members 27A and 27B can be reliably projected. As a result, the grip members 27A and 27B can be reliably hung with a finger, and the mixing operation can be smoothly performed.

As shown in FIG. 6, the total length L1 of the syringe kit 12 in which the male syringe 16 and the female syringe 18 are connected to each other is different from the length L2 between the first mounting portion 54A and the second mounting portion 54B. In some cases. FIG. 6 shows a case where L1 is longer than L2, but conversely, L1 may be shorter than L2. On the other hand, in the initial state of the syringe kit 12, air is contained in the filling space formed on the tip side of the gasket in at least one barrel of the male syringe 16 and the female syringe 18. Therefore, even when the above L1 and L2 are different, the pusher (pusher 24A or pusher 24B) can be moved in the axial direction to some extent by the compression or expansion of the air existing in the filling space. Therefore, the syringe kit 12 can be attached to the mixing aid 14 without forcibly deforming the connecting portion 58.

[Second Embodiment]
The mixing aid 14a of the syringe system 10a according to the second embodiment shown in FIGS. 7 and 8 has a shorter overall length than the first embodiment (FIG. 7) to which the syringe kit 12 in the connected state can be attached. It can be transformed into the second form (FIG. 8). With this configuration, the mixing assisting tool 14a can be stored in a second form in a compact manner before the mixing assisting tool 14a is used. Further, after use, the mixing aid 14a can be transformed from the first form to the second form and disposed of compactly.

The connecting portion 58 of the mixing aid 14a has a first member 70 having a first mounting portion 54A and a second member 72 having a second mounting portion 54B. The first member 70 and the second member 72 are rotatably connected to each other via a hinge portion 74. Thereby, it is possible to realize the mixing assist tool 14a that can be transformed into the first form and the second form with a simple and economical configuration.

Specifically, the end 70a on the side opposite to the side where the first mounting portion 54A of the first member 70 is provided and the end on the side opposite to the side where the second mounting portion 54B of the second member 72 is provided. The portion 72a is rotatably connected around an axis a perpendicular to the longitudinal axis of the mixing aid 14. As a result, as shown in FIG. 8, the mixing assist tool 14a is configured to be foldable in a shape that can be folded at the intermediate portion of the connecting portion 58.

In the second embodiment, the second member 72 is shorter than the first member 70. As a result, as shown in FIG. 8, in the folded state of the mixing assisting tool 14a, the first mounting portion 54A and the second mounting portion 54B are arranged so as to be offset in the longitudinal direction of the mixing assisting tool 14a. A part of the second mounting portion 54B is inserted between the connecting members 60 on the first member 70 side. Therefore, the width of the mixing assist tool 14a in the folded state can be made smaller, and the size can be further reduced.

Of the second embodiment, the same or similar actions and effects as those of the first embodiment can be obtained with respect to the portion common to the first embodiment.

In the above-described embodiment, the pusher base end portions 30A and 30B do not have to have a flange shape. For example, the shaft portion 28A of the pusher 24A and the pusher base end portion 30A may be formed in an integral cylindrical shape (the same applies to the pusher 24B). In this case, for example, a notch is provided on the outer peripheral surfaces of the pusher base end portions 30A and 30B, and a protrusion that can be inserted into the notch is used as a first mounting portion 54A and a second mounting portion 54B as a mixing auxiliary tool. 14 is provided. Alternatively, an insertion opening is provided on the base end surfaces of the pusher base ends 30A and 30B, and the insertion protrusions that can be inserted into the insertion openings serve as the first mounting portion 54A and the second mounting portion 54B. It is provided in.

The present invention is not limited to the above-described embodiment, and various modifications can be made without departing from the gist of the present invention.

Claims (10)

A mixing aid (14, 14a) that can be attached to a syringe kit (12) with two syringes (16, 18) whose tips can be connected to each other to mix the drug.
Each of the two syringes (16, 18) is slidable into a barrel (20, 40) having a finger grip (26A, 26B) projecting radially outward at the base end and into the barrel (20, 40). The gasket (22, 42) arranged in the barrel (22, 42), which is connected to the gasket (22, 42) and has a pusher base end portion (30A, 30B) at the base end, and the base end of the barrel (20, 40). The finger grips (26A, 26B) are provided with pushers (24A, 24B) protruding from the opening toward the base end, and the finger grips (26A, 26B) are formed in a non-circular shape having a minor axis and a major axis.
The mixing aids (14, 14a) are
A first mounting portion (54A) to which the pusher base end portion (30A) of one of the syringe kits (12) in a connected state in which the two syringes (16, 18) are connected to each other can be mounted.
A second mounting portion (54B) to which the pusher base end portion (30B) can be mounted on the other side of the syringe kit (12) in the connected state.
A rod-shaped connecting portion (58) for connecting the first mounting portion (54A) and the second mounting portion (54B) is provided.
The width (W) of the connecting portion (58) in the direction perpendicular to the longitudinal direction of the mixing aid (14, 14a) is the length (La) along the major axis of the finger grips (26A, 26B). , Lb)
The finger grips (26A, 26B) with one and the other pusher base ends (30A, 30B) mounted on the first mounting portion (54A) and the second mounting portion (54B), respectively. There protrudes outside the said connecting portion (58),
The mixing aid (14, 14a) can be transformed into a first form in which the syringe kit (12) in a connected state can be attached and a second form in which the total length is shorter than that of the first form.
Mixing aids (14, 14a), characterized in that. In the mixing aid (14, 14a) according to claim 1,
The connecting portion (58) has two connecting members (60) extending so as to face each other.
One end side of each of the two connecting members (60) is connected to the first mounting portion (54A).
The other end side of each of the two connecting members (60) is connected to the second mounting portion (54B).
With the syringe kit (12) in the connected state attached to the mixing aids (14, 14a), the syringe kit (12) is arranged between the two connecting members (60).
Mixing aids (14, 14a), characterized in that. In the mixing aid (14, 14a) according to claim 1 or 2.
The first mounting portion (54A) and the second mounting portion (54B) have a finger contact portion (62) that supports the proximal end surface of the pusher base end portions (30A, 30B) and is pressed by a finger. death,
The width of the finger pad portion (62) in the direction perpendicular to the longitudinal direction of the mixing aid (14, 14a) is larger than the diameter (D) of the pusher base end portion (30A, 30B), and It is smaller than the length (La, Lb) of the finger grips (26A, 26B) along the long axis.
Mixing aids (14, 14a), characterized in that. In the mixing aid (14a) according to claim 1,
The connecting portion (58) has a first member (70) having the first mounting portion (54A) and a second member (72) having the second mounting portion (54B). The member (70) and the second member (72) are rotatably connected to each other via a hinge portion (74).
A mixing aid (14a), characterized in that. A syringe kit (12) with two syringes (16, 18) whose tips can be connected to each other to mix the drug.
A mixing aid (14, 14a) to which the syringe kit (12) in a connected state in which the two syringes (16, 18) are connected to each other can be attached.
A syringe system (10, 10a) equipped with the above.
Each of the two syringes (16, 18) has a barrel (20, 40) having a finger grip (26A, 26B) at its base and a gasket (20, 40) slidably disposed within the barrel (20, 40). 22, 42), connected to the gasket (22, 42), and having a pusher base end portion (30A, 30B) at the base end, from the base end opening of the barrel (20, 40) toward the base end. With a protruding pusher (24A, 24B), the finger grip (26A, 26B) is formed in a non-circular shape with a minor axis and a major axis.
The mixing aids (14, 14a) are
A first mounting portion (54A) to which the pusher base end portion (30A) of one of the syringe kits (12) in the connected state can be mounted.
A second mounting portion (54B) to which the pusher base end portion (30B) can be mounted on the other side of the syringe kit (12) in the connected state.
A rod-shaped connecting portion (58) for connecting the first mounting portion (54A) and the second mounting portion (54B) is provided.
The width (W) of the connecting portion (58) in the direction perpendicular to the longitudinal direction of the mixing assist tool (14, 14a) is the length of the pusher base end portion (30A, 30B) along the major axis. Smaller than Sa (La, Lb),
The finger grips (26A, 26B) are mounted in a state where one and the other pusher base ends (30A, 30B) are mounted on the first mounting portion (54A) and the second mounting portion (54B). wherein protrudes outside the connecting portion (58),
The mixing aid (14, 14a) can be transformed into a first form in which the syringe kit (12) in a connected state can be attached and a second form in which the total length is shorter than that of the first form.
Syringe system (10, 10a). In the syringe system (10, 10a) according to claim 5.
The connecting portion (58) has two connecting members (60) extending so as to face each other.
One end side of each of the two connecting members (60) is connected to the first mounting portion (54A).
The other end side of each of the two connecting members (60) is connected to the second mounting portion (54B).
With the syringe kit (12) in the connected state attached to the mixing aids (14, 14a), the syringe kit (12) is arranged between the two connecting members (60).
Syringe system (10, 10a). In the syringe system (10, 10a) according to claim 5 or 6.
The first mounting portion (54A) and the second mounting portion (54B) have a finger contact portion (62) that supports the proximal end surface of the pusher base end portions (30A, 30B) and is pressed by a finger. death,
The width of the finger pad portion (62) in the direction perpendicular to the longitudinal direction of the mixing aid (14, 14a) is larger than the diameter (D) of the pusher base end portion (30A, 30B), and It is smaller than the length (La, Lb) of the finger grips (26A, 26B) along the long axis.
Syringe system (10, 10a). In the syringe system (10a) according to claim 5.
The connecting portion (58) has a first member (70) having the first mounting portion (54A) and a second member (72) having the second mounting portion (54B). The member (70) and the second member (72) are rotatably connected to each other via a hinge portion (74).
A syringe system (10a), characterized in that. In the syringe system (10, 10a) according to any one of claims 5 to 8.
In the initial state of the syringe kit (12), a filling space formed on the distal end side of the gasket (22, 42) in the barrel (20, 40) of at least one of the two syringes (16, 18). Has air in it,
Syringe system (10, 10a). In the syringe system (10, 10a) according to any one of claims 5 to 9.
The tips of the barrels (20, 40) of the two syringes (16, 18) are provided with screwing protrusions that can be screwed together.
A flange portion (26d, 40f) protruding outward in the radial direction is provided at the base end of the barrel (20, 40).
The finger grips (26A, 26B) are grip members (27A, 27B) rotatably mounted on the flange portions (26d, 40f) about the axis of the barrel (20, 40).
Syringe system (10, 10a).

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