JP6977221B2 - Disinfectant composition, manufacturing method of disinfectant composition - Google Patents

Description

The present invention relates to a disinfectant composition. In particular, the present invention relates to a sterilizing agent composition having a low odor, an excellent sterilizing effect, and an excellent storage stability.

The peracetic acid preparation is a disinfectant consisting of an equilibrium system of acetic acid, hydrogen peroxide, and peracetic acid (formula (1) below). It is used for cleaning bottles, etc.
CH ₃ COOH + H ₂ O ₂ ⇔ CH ₃ COO ₂ H + H ₂ O (1)

Although peracetic acid preparations have bactericidal activity against a wide range of microbial species, they have a strong pungent odor similar to acetic acid, so they are engaged in work when used in an environment that is not sealed or is not sufficiently ventilated. There was a problem in terms of safety for people.

The use of other odorless percarboxylic acids as an alternative to peracetic acid has been considered. For example, Patent Documents 1 and 2 disclose compositions using perglutaric acid. Patent Document 3 discloses a mixed aqueous solution of a perdicarboxylic acid (perglutaric acid and persuccinic acid, or perglutaric acid and persuccinic acid and peradipic acid).

Japanese Unexamined Patent Publication No. 53-81619 Japanese Unexamined Patent Publication No. 2008-184405 Patent No. 3537540

However, these percarboxylic acids are more unstable than peracetic acid, are easily autolyzed, and need to be stored at a low temperature, so that they have not been widely put into practical use.
Therefore, it is an object of the present invention to provide a sterilizing agent composition that does not have an irritating odor like a peracetic acid preparation and has excellent sterilizing efficacy and excellent storage stability. ..

As a result of diligent studies to solve the above problems, the present inventor has made a conventional disinfectant composition containing a stabilizer such as lactic acid, hydrogen peroxide and phosphonic acid, and an acid catalyst using a percarboxylic acid. We have found that the problems of the disinfectant composition of the above can be solved, and have completed the present invention.

The disinfectant composition according to the first aspect of the present invention comprises 0.1 to 15 parts by mass of lactic acid, 10 to 50 parts by mass of hydrogen peroxide, 3 to 12 parts by mass of a stabilizer, and 1 to 1 parts of an acid catalyst. It contains a composition comprising 15 parts by mass; with water;
With this structure, it is possible to obtain a sterilizing agent composition that does not have a pungent odor like peracetic acid, has a sterilizing effect equal to or higher than that of peracetic acid, and has excellent storage stability.

The disinfectant composition according to the second aspect of the present invention contains the lactic acid and the perlactic acid produced from the hydrogen peroxide in the disinfectant composition according to the first aspect of the present invention. The stabilizer is at least one of organic phosphonic acid and pyridinecarboxylic acid.
With this configuration, since each component is blended in a specific blending ratio, the perlactic acid produced by the reaction between lactic acid and hydrogen peroxide can be stably present. Therefore, it can be a disinfectant composition containing perlactic acid as a main component.

The disinfectant composition according to the third aspect of the present invention comprises lactic acid; hyperlactic acid; a stabilizer; the stabilizer is at least one of an organic phosphonic acid and a pyridinecarboxylic acid. Is.
With this structure, it is possible to obtain a sterilizing agent composition that does not have a pungent odor like peracetic acid, has a sterilizing effect equal to or higher than that of peracetic acid, and has excellent storage stability.

The disinfectant composition according to the fourth aspect of the present invention is the disinfectant composition according to the third aspect of the present invention, wherein the total amount of the lactic acid and the hydrogen peroxide is 0.1 to 15 parts by mass; It contains 1 to 50 parts by mass of hydrogen peroxide, 3 to 12 parts by mass of the stabilizer, 1 to 15 parts by mass of an acid catalyst, and water.
With this configuration, since each component is composed of a specific composition ratio, the perlactic acid produced by the reaction between lactic acid and hydrogen peroxide can be stably present. Therefore, it can be a disinfectant composition containing perlactic acid as a main component.

In the disinfectant composition according to the fifth aspect of the present invention, the reaction between the lactic acid and the hydrogen peroxide is chemical in the disinfectant composition according to the second or fourth aspect of the present invention. When the concentration of the hydrogen peroxide when the equilibrium state is reached is taken as the initial concentration, the initial concentration of the hydrogen peroxide remains 70% by mass or more of the initial concentration after the disinfectant composition is stored at room temperature for 30 days. ..
With this configuration, hyperlactic acid does not self-decompose and is sufficiently present in the sterilizing agent composition even after 30 days, so that the sterilizing effect can be sufficiently exhibited.

The disinfectant composition according to the sixth aspect of the present invention does not contain peracetic acid in the disinfectant composition according to any one of the first to fifth aspects of the present invention. The term "not contained" means that the substance is not contained at all, or even if it is contained, the amount is such that the odor of peracetic acid cannot be sensed by the human sense of smell.
With this configuration, it is possible to obtain a disinfectant composition having no strong pungent odor similar to acetic acid.

The method for producing a disinfectant composition according to a seventh aspect of the present invention comprises 0.1 to 15 parts by mass of lactic acid; 10 to 50 parts by mass of hydrogen peroxide; and 3 to 12 parts by mass of a stabilizer. And; a step of blending 1 to 15 parts by mass of an acid catalyst; with water;
With this structure, it is possible to produce a sterilizing agent composition that does not have a pungent odor like peracetic acid, has a sterilizing effect equal to or higher than that of peracetic acid, and has excellent storage stability.

The sterilizing agent composition of the present invention does not have a pungent odor like a peracetic acid preparation, and can have excellent sterilizing efficacy and excellent storage stability.

It is a graph which shows the time-dependent change of the perlactic acid concentration and the hydrogen peroxide concentration of Example 2. It is a graph which shows the time-dependent change of the perlactic acid concentration and the hydrogen peroxide concentration of Example 6. It is a graph which shows the time-dependent change of the peracetic acid concentration and the hydrogen peroxide concentration of the peracetic acid preparation A. It is a graph which shows the time-dependent change of the peracetic acid concentration and the hydrogen peroxide concentration of the peracetic acid preparation B.

Hereinafter, embodiments of the present invention will be described with reference to the drawings. In each figure, parts that are the same as or correspond to each other are designated by the same or similar reference numerals, and duplicated description will be omitted. Further, the present invention is not limited to the following embodiments.

[Bactericidal composition]
The present invention is a disinfectant composition containing perlactic acid as a main component, and is a disinfectant composition based on an equilibrium system of lactic acid, hydrogen peroxide, and superlactic acid (the following formula (2)). The "main component" refers to a component that accounts for more than 50% by mass of the total amount of the percarboxylic acid. Alternatively, it may be 60% by mass or more, preferably 70% by mass or more, more preferably 80% by mass or more, and particularly preferably 90% by mass or more.
The blended lactic acid and hydrogen peroxide react to produce hyperlactic acid. After this reaction reaches equilibrium, when superlactic acid is consumed, lactic acid and hydrogen peroxide react again to produce more superlactic acid in order to maintain the equilibrium state. In this way, the reaction continues and supplies hyperlactic acid.
In the disinfectant composition of the present application, by blending a specific compound in a specific ratio, perlactic acid can exist in a stable state for a long period of time without self-decomposition, and has a pungent odor like a peracetic acid preparation. It can have an excellent sterilizing effect (strong oxidizing action).
CH ₃ CH (OH) COOH + H ₂ O ₂ ⇔ _{CH 3} CH (OH) COO ₂ H + H ₂ O (2)

Each component to be blended in the disinfectant composition of the present invention will be described below separately for the component (A), the component (B), the component (C), the component (D), and the component (E).
The disinfectant composition contains a composition containing (A) component, (B) component, (C) component, and (D) component in the following proportions, and water as the (E) component. In the composition, lactic acid is 0.1 to 15 parts by mass as a component (A), hydrogen peroxide is 15 to 50 parts by mass as a component (B), and a stabilizer is 3 to 12 parts by mass as a component (C). As the component (D), an acid catalyst is blended in a proportion of 1 to 15 parts by mass.
For example, component (A); lactic acid 0.1 to 15% by mass, component (B); hydrogen peroxide 15 to 50% by mass, component (C); stabilizer 3 to 12% by mass, component (D); acid. The catalyst may be blended so that 1 to 15% by mass of the catalyst, the component (E) as a residue; water is contained, and the total amount of the components (A) to (E) is 100% by mass.

Alternatively, 4.5 to 9 parts by mass of lactic acid as the component (A), 14 to 21 parts by mass of hydrogen peroxide as the component (B), and 0.6 to 6 parts by mass of the stabilizer as the component (C). D) As a component, an acid catalyst may be blended in a proportion of 3.5 to 11 parts by mass.
For example, component (A); lactic acid 4.5 to 9% by mass, component (B); hydrogen peroxide 14 to 21% by mass, component (C); stabilizer 0.6 to 6% by mass, component (D). The acid catalyst may be blended so that 3.5 to 11% by mass of the acid catalyst, the component (E) as a residue; water is contained, and the total amount of the components (A) to (E) is 100% by mass.

[(A) component]
The component (A) is a carboxylic acid that produces a hypercarboxylic acid, and in the present invention, lactic acid, which is a hydroxycarboxylic acid, is used. Lactic acid may be L lactic acid, D lactic acid, or a mixture thereof.
In the ratio of (A) component: (B) component: (C) component: (D) component, the ratio of lactic acid of the (A) component is preferably 0.1 to 15 parts by mass, more preferably 4 to 9 parts by mass. .. When the concentration of lactic acid is 0.1 part by mass or more, the sterilizing property does not deteriorate, and when it is 15 parts by mass or less, the generated superlactic acid is hardly decomposed.

[(B) component]
The component (B) is hydrogen peroxide that reacts with lactic acid.
In the ratio of (A) component: (B) component: (C) component: (D) component, the ratio of hydrogen peroxide of the (B) component is preferably 10 to 50 parts by mass, more preferably 15 to 30 parts by mass. .. When the ratio of hydrogen peroxide is 10 parts by mass or more, superlactic acid is likely to be generated, and when it is 50 parts by mass or less, it is preferable from the viewpoint of the stability of superlactic acid.

[(C) component]
The component (C) is a stabilizer for keeping the produced hyperlactic acid in a stable state.
Examples of the stabilizer of the component (C) include organic phosphonic acids such as 1-hydroxyethylidene-1,1-diphosphonic acid, aminotri (methylenephosphonic acid) and ethylenediaminetetra (methylenephosphonic acid), or picolinic acid and dipicolinic acid. A pyridinecarboxylic acid such as quinophosphoric acid can be selected. One type of stabilizer may be used, or a plurality of types may be mixed and used.
In the ratio of the component (A): the component (B): the component (C): the component (D), the ratio of the stabilizer of the component (C) is preferably 3 to 12 parts by mass, more preferably 5 to 10 parts by mass. .. When the ratio of the stabilizer is 3 parts by mass or more, superlactic acid is likely to be generated, and when it is 12 parts by mass or less, the generated superlactic acid is less likely to be decomposed, which is economically preferable.

[(D) component]
The component (D) is an acid catalyst for accelerating the reaction between lactic acid and hydrogen peroxide.
As the acid catalyst of the component (D), phosphoric acid, sulfuric acid, nitric acid, methanesulfonic acid and the like can be used. One type of acid catalyst may be used, or a plurality of types may be mixed and used.
In the ratio of the component (A): the component (B): the component (C): the component (D), the ratio of the acid catalyst of the component (D) is preferably 1 to 15 parts by mass. When the ratio of the acid catalyst is 1 part by mass or more, the production rate and the amount of superlactic acid produced are less likely to decrease, and when the ratio is 15 parts by mass or less, the produced perlactic acid is less likely to be decomposed, which is economically preferable.

[(E) component]
The component (E) is water added together with the components (A), (B), (C), and (D) when they are aqueous solutions, or water added separately. be.
Examples of the water of the component (E) include ion-exchanged water, soft water, pure water, tap water, etc., but from the viewpoint of the stability of hyperlactic acid in the disinfectant composition, ion-exchanged water or pure water is used. preferable.

[others]
The disinfectant composition of the present invention may be a composition comprising (A) component, (B) component, (C) component, (D) component, and (E) component, and impairs the effect of the present invention. To the extent that it does not exist, other components usually used in the art can be added to the disinfectant composition of the present invention. Examples of such components include surfactants, defoamers, hydrotropes, thickeners, fragrances, pigments, pH adjusters and the like.

[Production method]
The disinfectant of the present invention is obtained by weighing and mixing the above-mentioned component (A), component (B), component (C), component (D), component (E) and a surfactant or the like, if necessary. The composition can be obtained. After mixing, the period until the reaction between lactic acid and hydrogen peroxide reaches an equilibrium state varies depending on the temperature, so adjust appropriately.
The disinfectant composition of the present invention contains perlactic acid produced by the reaction of lactic acid and hydrogen peroxide after mixing, and the total amount of lactic acid and perlactic acid is 0.1 to 15 parts by mass; hydrogen peroxide 1 to 1 It contains 50 parts by mass; a stabilizer of 3 to 12 parts by mass; an acid catalyst of 1 to 15 parts by mass; and water;
Since the generated superlactic acid has excellent storage stability, when the concentration of superlactic acid when the reaction between lactic acid and hydrogen peroxide reaches a chemical equilibrium state is set as the initial concentration, then the composition of the disinfectant is used. Even after the product is stored at room temperature for 30 days, the perlactic acid does not self-decompose, and preferably 70% by mass or more, more preferably 80% by mass or more of the initial concentration can remain.

In the disinfectant composition of the present invention, the prepared disinfectant composition can be used as it is as a disinfectant. Alternatively, it may be used as a diluted aqueous solution diluted by adding water, or a diluted mixture diluted with a solvent or the like. When the disinfectant composition is diluted and used, the prepared disinfectant composition may be diluted to, for example, 0.01 to 50% by mass, or 0.1 to 5% by mass. May be good.

As described above, the sterilizing agent composition of the present invention has less odor (acid odor) than the peracetic acid preparation and has a sterilizing effect equal to or higher than that of the peracetic acid preparation. The safety of workers in an inadequate environment is significantly improved compared to the peracetic acid preparation. Further, the peroxide solution obtained by the present invention is stable even at room temperature, and the storage stability is significantly improved as compared with a percarboxylic acid such as peradipic acid which requires low temperature storage.
As described above, the disinfectant composition of the present invention can be used as an alternative to the conventional peracetic acid preparation and other preparations using a percarboxylic acid. For example, it can be used for the following cleaning, sterilization, and sterilization. Examples include artificial dialysis equipment, endoscopes, spaces / floors / walls of sterile pharmaceutical rooms, piping and tanks for ultrapure water / pure water, PET bottles, food manufacturing equipment, and the like.

Hereinafter, the present invention will be specifically described with reference to Examples and Comparative Examples. However, the present invention is not limited to the contents described in the following examples.

Each component blended in Examples and Comparative Examples is shown below.
(A) Component A: Lactic acid (B) component B: Hydrogen peroxide (hydrogen peroxide solution, concentration 30%)
(C) Component C: 1-hydroxyethane-1,1-diphosphonic acid (concentration 60%)
(D) Component D-1: Methanesulfonic acid D-2: Phosphoric acid D-3: Sulfuric acid D-4: Nitric acid (concentration 60%)
(E) Component E: Ion-exchanged water

[Comparative Examples 1 and 2, Examples 1 to 7]
The disinfectant composition was prepared based on the ratios shown in Tables 1 and 2. Dilute each disinfectant composition with ion-exchanged water to prepare a diluted solution, and measure the peroxide concentration according to the titration method of hydrogen peroxide / peracetic acid concentration with potassium permanganate and sodium thiosulfate. gone. The numerical values of the formulations of Comparative Examples and Examples in Tables 1 and 2 indicate the mass% concentration of pure content.

評価）
◎：２５℃で３０日保管後の過乳酸濃度が、化学平衡状態における初期濃度の８０質量％以上
○：２５℃で３０日保管後の過乳酸濃度が、化学平衡状態における初期濃度の７０質量％以上８０質量％未満
×：２５℃で３０日保管後の過乳酸濃度が、化学平衡状態における初期濃度の７０質量％未満

evaluation)
⊚: The perlactic acid concentration after storage at 25 ° C. for 30 days is 80% by mass or more of the initial concentration in the chemical equilibrium state. % Or more and less than 80% by mass ×: The perlactic acid concentration after storage at 25 ° C. for 30 days is less than 70% by mass of the initial concentration in the chemical equilibrium state.

評価）
◎：２５℃で３０日保管後の過乳酸濃度が、化学平衡状態における初期濃度の８０質量％以上
○：２５℃で３０日保管後の過乳酸濃度が、化学平衡状態における初期濃度の７０質量％以上８０質量％未満
×：２５℃で３０日保管後の過乳酸濃度が、化学平衡状態における初期濃度の７０質量％未満

evaluation)
⊚: The perlactic acid concentration after storage at 25 ° C. for 30 days is 80% by mass or more of the initial concentration in the chemical equilibrium state. % Or more and less than 80% by mass ×: The perlactic acid concentration after storage at 25 ° C. for 30 days is less than 70% by mass of the initial concentration in the chemical equilibrium state.

[Confirmation of peroxide stability]
The peroxide was measured according to the titration method of hydrogen peroxide / peracetic acid concentration with potassium permanganate and sodium thiosulfate. Peroxide measured with sodium thiosulfate is calculated as the concentration of superlactic acid because superlactic acid (lactic acid hydroperoxide, CH ₃ CH (OH) COO _{2 H) is generated by the reaction between lactic acid and hydrogen peroxide.} did.

[Test method]
(1) 5 ml of a sample (2% by mass solution of each disinfectant composition) was collected in a 100 ml Erlenmeyer flask, and 10 ml of a 10 w / v% sulfuric acid solution was added. Titrated with 0.1N potassium permanganate solution until pale pink (Aml).
(2) After adding 1 ml of 10 w / v% potassium iodide solution to this solution, titrate with 1 / 70.9 N sodium thiosulfate standard solution until it becomes pale yellow, add about 1 ml of 1 w / v% starch solution, and darken. Titration was performed until the blue color disappeared (B ml). For the measurement of the blank, 1 ml of ion-exchanged water was collected and the above operation was performed to determine the titration amount (B ₀ ml) of 1 / 70.9 N sodium thiosulfate standard solution.
-Hydrogen peroxide concentration (w / v%) in the drug substance = A x 1.7 x F1
A: Titration of 0.1N potassium permanganate solution (ml)
Factor of F1: 0.1N potassium permanganate solution ・ Perlactic acid concentration in the original (w / v%) = (BB ₀ ) × 0.74 × F2
B: Titration of 1 / 70.9N sodium thiosulfate standard solution (ml)
B ₀ : Blank titration (ml)
F2: Factor of 1 / 70.9N sodium thiosulfate standard solution * In the case of peracetic acid, the coefficient (0.74) was set to 0.53.

[result]
As a result of investigating the changes over time of the hydrogen peroxide concentration and the peracetic acid concentration of Examples 2 and 6 for 6 months, the commercially available peracetic acid preparation A (Tech P-10, manufactured by ADEKA Corporation) and the peracetic acid preparation B It showed the same level of stability as the hydrogen peroxide concentration and peracetic acid concentration of (Oxypal AT, manufactured by Hodoya Chemical Industry Co., Ltd.) (FIGS. 1 to 4).

[Comparison of odors]
In order to compare the odors of Example 2 and the commercially available peracetic acid preparation A, the odors were evaluated by the following method.

[Test method]
(1) Three 300 ml beakers were prepared, one was filled with a test solution adjusted to each concentration, and the other two were filled with 270 ml of ion-exchanged water (blank), and allowed to stand at 25 ° C.
(2) We asked the panelists to select the one that smells from the three, and asked what kind of smell it had. Considering the exhaustion of the sense of smell, the tests were conducted in order from the one with the lowest concentration to the one with the highest concentration.

[Result Example 2]
At 0.001% by weight, half of the panelists detected some odor. At 0.01% by weight, most panelists detected some odor. At 0.1% by weight, more than half of the panelists perceived a sour odor. At 1% by weight, all panelists sensed the odor. There were many evaluations that the 1% by mass solution had neither a good odor nor an unpleasant odor.

[Results Commercially available peracetic acid preparation A]
At 0.001% by weight, more than half of the panelists detected some odor. At 0.01% by mass or more, all panelists sensed a specific (sour) odor, and some panelists evaluated it as a "pungent odor". At 0.1% by weight, 4 out of 8 perceived a "pungent odor". Six people evaluated the 1% by weight solution as a "pungent odor".

評価）
◎：不正解または判別不能
○：何か臭いがする（他のサンプルと違う）
△：何の臭いであるか感知（どのような臭いか具体的に言える）
×：刺激臭を感知

evaluation)
◎: Incorrect or indistinguishable ○: Something smells (different from other samples)
△: Sensing what kind of odor (specifically say what kind of odor it is)
×: Detects pungent odor

[Sterilization efficacy test]
The sterilizing efficacy of peracetic acid and perlactic acid was compared by the following test methods. In order to see the difference in eradication efficacy, Bacillus subtilis and Bacillus cereus, which are spore-forming bacteria and have relatively high chemical resistance, were selected as the bacterial species.

[Test bacterial species]
Bacillus subtilis: NBRC3134
Bacillus cereus: A bacterium isolated from an alkaline cleaning solution in a dairy factory.

[Test method Preparation of bacterial solution]
(1) Bacteria were inoculated on a standard agar plate medium and cultured at 37 ° C. for 7 days.
(2) The bacteria generated on the plate medium were suspended in 40 ml of sterile physiological saline.
(3) The mixture was heated in a water bath at 65 ° C. for 30 minutes, rapidly cooled with water at 25 ° C., centrifuged at 4500 rpm for 15 minutes, the supernatant was discarded, and the precipitate was suspended in 40 ml of physiological saline.
(4) The steps of (3) were repeated twice in total.
(5) were serially diluted in 10 to 10 ^{7 times,} 10 5 to 10 ⁷ fold dilutions taking 1 ml, was added to the compact dry (Nissui Pharmaceutical Co. simple media, for the number of general bacteria measurement).
(6) After culturing at 37 ° C. for 48 hours, the dilution ratio at which the number of colonies was within the range of 30 to 300 was counted and divided by 10 to obtain the initial number of bacteria.

[Test method sterilization efficacy test]
(7) 1 ml of the bacterial solution was inoculated into 9 ml of the disinfectant solution and kept at 25 ° C. in a water bath (hereinafter referred to as a test solution).
(8) After a predetermined time, ^{1 ml of the test solution was added to 9 ml * of} the neutralizing solution, serially diluted with sterile phosphate buffered saline, and 1 ml of each diluted solution was added to the compact dry.
(9) After culturing at 37 ° C. for 48 hours, the dilution ratio at which the number of colonies was within the range of 30 to 300 was counted, and the number of bacteria in each test solution was determined.
* Lecithin 10 g, Tween80 30 g, L-histidine 1 g, thiosulfate Na pentahydrate 31 g, and phosphate buffer (pH 7.2) 250 mM 100 ml are messed up with 1000 ml of ion-exchanged water and sterilized by autoclave.

[result]
As a result of the test, Bacillus subtilis showed the same sterilizing effect as the peracetic acid and the perlactic acid preparation having the same molar concentration. For Bacillus cereus, the eradication efficacy of the perlactic acid preparation was higher than that of the equimolar concentration of peracetic acid.

Bacterial species: Bacillus subtilis (NBRC3134)
Initial bacteria ^{count: 8.3 × 10 6 (CFU /} ml)
Test temperature: 25 ° C, action time: 10 minutes

Bacterial species: Bacillus cereus (isolated from a dairy factory)
Initial bacteria ^{count: 5.6 × 10 5 (CFU /} ml)
Test temperature: 25 ° C, action time: 30 minutes

Claims (7)

A disinfectant composition based on an equilibrium system of lactic acid, hydrogen peroxide, and superlactic acid (formula (2) below) ( excluding quaternary ammonium compounds) .
0.1 to 15 parts by mass of lactic acid, 10 to 50 parts by mass of hydrogen peroxide, 3 to 12 parts by mass of stabilizer, and 1 to 15 parts by mass of acid catalyst (excluding lactic acid) are blended. With the composition of
With water;
Disinfectant composition.
CH ₃ CH (OH) COOH + H ₂ O ₂ ⇔ _{CH 3} CH (OH) COO ₂ H + H ₂ O (2) A disinfectant composition based on an equilibrium system of lactic acid, hydrogen peroxide, and superlactic acid (formula (2) below).
0.1 to 15 parts by mass of lactic acid, 10 to 50 parts by mass of hydrogen peroxide, 3 to 12 parts by mass of stabilizer, and 1 to 15 parts by mass of acid catalyst (excluding lactic acid) are blended. With the composition of
Consists of water;
Disinfectant composition.
CH ₃ CH (OH) COOH + H ₂ O ₂ ⇔ _{CH 3} CH (OH) COO ₂ H + H ₂ O (2) Containing the lactic acid and the hyperlactic acid produced from the hydrogen peroxide,
The stabilizer is at least one of an organic phosphonic acid and a pyridinecarboxylic acid.
The disinfectant composition according to claim 1 or 2. A disinfectant composition based on an equilibrium system of lactic acid, hydrogen peroxide, and superlactic acid (formula (2) below) ( excluding quaternary ammonium compounds) .
With a total amount of 0.1 to 15 parts by mass of the lactic acid and the superlactic acid;
With 1 to 50 parts by mass of hydrogen peroxide;
Stabilizer with 3-12 parts by mass;
With 1 to 15 parts by mass of acid catalyst (excluding lactic acid);
With water;
The stabilizer is at least one of an organic phosphonic acid and a pyridinecarboxylic acid.
Disinfectant composition.
CH ₃ CH (OH) COOH + H ₂ O ₂ ⇔ _{CH 3} CH (OH) COO ₂ H + H ₂ O (2) When the concentration of the superlactic acid when the reaction between the lactic acid and the hydrogen peroxide reaches a chemical equilibrium state is used as the initial concentration,
The initial concentration of the hyperlactic acid is such that 70% by mass or more of the initial concentration remains after the disinfectant composition is stored at room temperature for 30 days.
The disinfectant composition according to any one of claims 1 to 4. Does not contain peracetic acid,
The disinfectant composition according to any one of claims 1 to 5. A method for producing a disinfectant composition (excluding quaternary ammonium compounds ) based on an equilibrium system of lactic acid, hydrogen peroxide, and superlactic acid (formula (2) below).
Lactic acid is 0.1 to 15 parts by mass;
Hydrogen peroxide with 10 to 50 parts by mass;
Stabilizer with 3-12 parts by mass;
Add 1 to 15 parts by mass of acid catalyst (excluding lactic acid);
With a step of blending with water;
A method for producing a disinfectant composition.
CH ₃ CH (OH) COOH + H ₂ O ₂ ⇔ _{CH 3} CH (OH) COO ₂ H + H ₂ O (2)

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