JP7017232B2 - Lighting system - Google Patents

Description

The present invention can be used for work that keeps the inside sterile and work that handles substances that affect the human body inside, and lighting that illuminates the inside of the work room that can be airtightly shielded from the external environment. It's about the system.

It is important to maintain the aseptic condition inside the isolator, clean bench, RABS (access restriction barrier system), clean room, etc. In particular, in the decontamination of a sterile room, which is a working room for manufacturing pharmaceutical products, it is necessary to complete advanced decontamination validation in line with GMP (Good Manufacturing Practice).

Therefore, the inside of these work rooms is decontaminated on a regular basis. Decontamination gas such as hydrogen peroxide gas is used for decontamination, but when the room is supplied with decontamination gas or when the room is filled with decontamination gas, a sterile room is mistakenly used. It is dangerous to enter. Further, if the door of the sterile room is opened in such a state, not only the internal decontamination work is impaired, but also the external environment is contaminated and the health of the worker outside the work room is adversely affected. On the contrary, if the door of the sterile room is opened when the inside of the work room is in a sterile state, the sterile state inside is impaired.

Therefore, it is possible for workers outside the work room to easily recognize that the inside of the work room is in an aseptic state in which decontamination has been completed, or that the inside of the work room is in a dangerous state during decontamination work. is necessary. Furthermore, it is necessary for the operator to be able to easily recognize what kind of process or state the inside of the working room in the decontamination work is currently in.

On the other hand, in a containment work room where environmental pollutants are handled inside the work room, it is extremely dangerous to accidentally enter the work room or open the door of the work room when environmental pollutants are present in the room. .. Therefore, it is necessary to make it easy for workers outside the work room to recognize the presence of environmental pollutants in the room.

Further, as described above, not only the state of the inside of the work room is recognized, but also the airtightness of the inside is destroyed during the work of confirming the airtightness of the inside and the work in the work room. It is important to issue a warning to the worker even in such a case. Further, when working through a glove such as an isolator, a dangerous state may occur depending on the operating state of the device inside the work room and the position of the worker's hand through the glove. Even in that case, it is important to promptly issue a warning to the worker.

As a method of notifying the operator of the internal state of the work room or issuing a warning, for example, a caution is displayed on the door of the work room being decontaminated, or a warning such as a pilot lamp indicating that decontamination is in progress. It is being displayed with a light. Further, in Patent Document 1 below, it is proposed to combine a fire alarm sensor and a warning unit as a method of notifying an operator of the existence of a fire in the work space of a clean bench.

Japanese Unexamined Patent Publication No. 2008-253203

By the way, in the clean bench proposed in Patent Document 1, a warning is issued in a hurry when a dangerous state occurs, and it cannot be adopted as a method of notifying an operator of the internal state of the work room. Further, in the caution display and the pilot lamp, there is a problem that the caution display and the pilot lamp are not turned on due to some work mistake, or the display and the pilot lamp are only in a specific position and the operator overlooks them. ..

Therefore, the present invention addresses the above-mentioned problems and makes it easy to change the internal state of the work room from any position with a simple configuration in the work room that can be airtightly shielded from the external environment. It is intended to provide a visible lighting system.

In solving the above problems, as a result of diligent research, the present inventors have found that the object of the present invention can be achieved by changing the color tone of the indoor lighting of the working room according to the internal state of the working room. The present invention has been completed.

That is, the lighting system according to the present invention is according to the description of claim 1.
It is a lighting system that illuminates the inside of the work room (10) that can be airtightly shielded from the external environment.
A lighting means having a work lighting lamp (61a, 61b) and a notification lighting lamp (62a, 62b) and having a plurality of color tones, and a control means for controlling the lighting means to change the color tone of the lighting. Have,
By changing the color tone of the notification lighting lamp by the control means and turning on the lighting of the color tone corresponding to the internal situation of the work room inside the work room.
It is characterized in that the environment inside the working room can be easily visually recognized from the outside of the working room through a viewing window provided on the wall portion of the working room.

Further, the present invention is the lighting system according to claim 1, according to claim 2.
In the decontamination work inside the work room
During the decontamination process of decontaminating the inside of the work room using a supply means that supplies decontamination gas.
The control means includes an operation sensor that detects an operation state of the supply means.
When the operation sensor detects the operating state of the supply means, the control means controls the lighting means to change the color tone of the notification lighting lamp to a different color tone according to each operating state. do.

Further, the present invention is the lighting system according to claim 1, according to claim 3.
In the decontamination work inside the work room
A decontamination process for decontaminating the inside of the work room using a supply means for supplying decontamination gas, and
After the decontamination step, the air supply means for supplying the diluting air for removing the decontamination gas filled inside the working room, and the decontaminating gas and the diluting air inside the working room are discharged. During the aeration process of aerating the inside of the work room using an exhaust means
The control means includes a concentration sensor (63) for detecting the concentration of the decontamination gas inside the work room.
When the concentration sensor detects the concentration of the decontamination gas inside the work room, the control means controls the lighting means to change the color tone of the notification lighting lamp for decontamination inside the work room. It is characterized by changing to a different color tone according to a change in gas concentration .

Further, the present invention is the lighting system according to claim 2 or 3 , according to claim 4.
In the decontamination work inside the work room
A humidity sensor (66) that detects the humidity inside the work room during the humidity control step in which the humidity control means is used before the decontamination step to adjust the humidity inside the work room. Equipped with
When the humidity sensor detects the humidity inside the work room, the control means controls the lighting means to change the color tone of the notification lighting lamp according to the change in the humidity inside the work room. It is characterized by changing to.

Further, the present invention is the lighting system according to claim 4, according to claim 5.
In the decontamination work inside the work room and the work in an aseptic state,
According to the state of each process during the humidity control process, humidity control completion, decontamination gas supply, decontamination gas supply completion, decontamination, aeration, aeration completion, and aseptic operation.
The control means controls the lighting means to change the color tone of the notification lighting lamp to a different color tone according to the state of each process .

Further, according to the description of claim 6, the present invention is the lighting system according to any one of claims 1 to 5.
In the airtightness inspection work that inspects or manages the airtightness inside the work room that is in a positive pressure state compared to the external environment.
The control means includes a pressure sensor (64) that detects the pressure inside the work room.
The control means calculates the decompression speed inside the work room based on the information from the pressure sensor, and when the decompression speed exceeds a predetermined value, the airtightness of the work room is in a broken state . It is characterized in that it determines and controls the lighting means to change the color tone of the notification lighting lamp to a color tone that warns of an abnormal situation .

Further, the present invention is the lighting system according to claim 1, according to claim 7.
The working chamber is a chamber of an isolator, and has a working device inside the chamber.
The control means includes an operation sensor that detects an operation state of the work device.
When the operation sensor detects the operating state of the working device, the control means controls the lighting means to change the color tone of the notification lighting lamp to a different color tone according to the operating state of the working device. It is characterized by.

Further, the present invention is the lighting system according to claim 7, according to claim 8.
The isolator has gloves for external workers to work inside the chamber.
The control means includes an area sensor (65) that detects the position of the glove.
When the area sensor detects when the worker puts his / her arm in the glove or when the glove is in the vicinity of the working device, the control means controls the lighting means to perform the notification lighting. It is characterized by changing the color tone of the lamp to call attention to the operator .

Further, according to the description of claim 9, the present invention is the lighting system according to any one of claims 1 to 8.
The working room is an isolator chamber.
In addition to the main body chamber, the isolator includes one or more pass boxes for putting articles in and out of the chamber.
The chamber and each pass box have independent lighting means.
The control means is characterized in that the lighting means is controlled to change the color tone of the notification lighting lamp of the chamber and each pass box simultaneously or separately.

Further, according to the description of claim 10, the present invention is the lighting system according to any one of claims 1 to 9.
The control means is characterized in that it controls the lighting means to make a change due to blinking of the lighting in addition to the change due to the color tone of the notification lighting lamp .

According to the above configuration, the lighting system according to the present invention is a lighting system that illuminates the inside of a work room that can be airtightly shielded from the external environment. Further, this lighting system has a lighting means and a control means. The lighting means includes a work lighting lamp and a notification lighting lamp, and has a plurality of color tones of lighting. Further, the control means controls the lighting means to change the color tone of the notification lighting lamp . Then, the lighting means is controlled by the control means to turn on the lighting of the color tone corresponding to the situation inside the work room inside the work room.

As a result, the environment inside the work room can be easily visually recognized from the outside of the work room through the viewing window provided on the wall of the work room. Therefore, according to the present invention, there is provided a lighting system that can easily visually recognize the internal state of the work room from any position with a simple configuration in the work room that can be airtightly shielded from the external environment. be able to.

Further, according to the above configuration, in the decontamination step of the decontamination work inside the work room, the inside of the work room is decontaminated by using the supply means for supplying the decontamination gas. At this time, the operation state of the supply means is detected by the operation sensor provided in the control means. Upon detection of this operation sensor, the control means controls the lighting means to change the color tone of the notification lighting lamp .

This makes it possible to easily visually recognize that the inside of the work room is in a decontamination process and requires attention. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, in the decontamination step and the aeration step of the decontamination work inside the work room, the supply means for supplying the decontamination gas and the decontamination gas filled inside the work room are eliminated. The inside of the work room is decontaminated and aerated by using the air supply means for supplying the dilution air and the exhaust means for discharging the decontamination gas and the dilution air inside the work room. At this time, the concentration sensor provided in the control means detects the concentration of the decontamination gas inside the work room. By the detection of this density sensor, the control means controls the lighting means to change the color tone of the notification lighting lamp according to the concentration of the decontamination gas.

This makes it possible to easily visually recognize whether the inside of the work room is in the decontamination process or at which stage of the aeration process. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, in the humidity control step of the decontamination work inside the work room, the humidity inside the work room is adjusted by using the humidity control means before the decontamination step. At this time, the humidity inside the work room is detected by the humidity sensor provided in the control means. By the detection of this humidity sensor, the control means controls the lighting means to change the color tone of the notification lighting lamp according to the humidity inside the work room.

This makes it possible to easily visually recognize at which stage of the humidity control process the inside of the work room is, or whether the humidity control is completed. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, in the decontamination work inside the work room and the work in an aseptic state, the humidity control process is completed, the humidity control is completed, the decontamination gas is being supplied, the decontamination gas is being supplied, and the decontamination is being performed. , The control means controls the lighting means to change the color tone of the notification lighting lamp according to the state of each process during aeration, aeration completion, and aseptic operation.

This makes it possible to easily visually recognize which step of the decontamination work the inside of the work room is in, or whether the work in an aseptic state is possible. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, the inside of the work room may be in a positive pressure state as compared with the external environment to inspect or manage the airtightness inside the work room. In this airtightness inspection work, the pressure inside the work room is detected by the pressure sensor provided in the control means. Further, the control means calculates the decompression speed inside the work room based on the information from the pressure sensor, and determines that the airtightness of the work room is in a broken state when the decompression speed exceeds a predetermined value. When it is determined that the airtightness is in a destructive state, the control means controls the lighting means to change the color tone of the notification lighting lamp .

As a result, it is possible to easily visually recognize that the airtightness inside the work room is in a destroyed state and is in a dangerous state. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, the working room is an isolator chamber, and has a working device inside the chamber. At this time, the operation state of the work device is detected by the operation sensor provided in the control means. Upon detection of this operation sensor, the control means controls the lighting means to change the color tone of the notification lighting lamp .

As a result, it is possible to easily visually recognize that the working device inside the chamber is in an operating state or the working device is in an abnormal state and requires attention. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, the working chamber is a chamber of an isolator, and the isolator has gloves for an outside worker to work inside the chamber. At this time, the area sensor provided in the control means detects when the worker puts his / her arm in the glove or when the glove is in the vicinity of the work device. Upon detection of this area sensor, the control means controls the lighting means to change the color tone of the notification lighting lamp .

This makes it easy to see that the worker is in a working state inside the chamber, or that the worker's gloves are in the vicinity of the work equipment and require attention. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, the working chamber is a chamber of an isolator, and the isolator includes one or two or more pass boxes for putting articles in and out of the chamber in addition to the main body chamber. Further, the chamber and each pass box have independent lighting means. At this time, the control means controls the lighting means to change the color tone of the chamber and the notification lighting lamp of each pass box simultaneously or separately.

This makes it possible to easily visually recognize the state of the chamber and each pass box. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

Further, according to the above configuration, the control means may control the lighting means to make a change due to blinking of the lighting in addition to the change due to the color tone of the notification lighting lamp .

This makes it easy to visually recognize the state of the chamber and each pass box, or the state of an emergency. Therefore, according to the above configuration, the above-mentioned action and effect can be exhibited more concretely.

It is the schematic of the cross section which looked at the inside of the isolator device which attached the lighting system which concerns on this invention from the side. It is a figure which shows the color tone change by a lighting system with respect to the flowchart of the airtightness inspection work in an Example. It is a figure which shows the color tone change by the lighting system with respect to the flow chart of the humidity control process and the decontamination process of the decontamination work in an Example. It is a figure which shows the color tone change by the lighting system with respect to the flowchart of the aeration process of the decontamination work in an Example. It is a figure which shows the color tone change by the lighting system with respect to the work in the chamber in a sterile state in an Example.

Hereinafter, an embodiment of the lighting system according to the present invention will be described with reference to the drawings. FIG. 1 is a schematic cross-sectional view of the inside of an isolator device equipped with the lighting system according to the present embodiment as viewed from a side surface. In the present embodiment, an isolator chamber will be described as an example of the "working room" referred to in the present invention, but the present invention is not limited to this, and the outside such as a clean bench, a RABS (access restricted barrier system), and a clean room will be described. It shall include an internal environment that is airtightly shielded from the environment.

First, the isolator device will be described. In FIG. 1, the isolator device 1 is composed of a gantry 2 mounted on a floor surface and an isolator main body 3 mounted on the gantry 2. The gantry 2 is surrounded by a wall material made of a stainless metal plate, and an electrical component and a machine room (not shown) are housed inside the gantry 2. The isolator main body 3 includes a chamber 10, an air supply mechanism 20, and an exhaust mechanism 30.

The isolator device 1 of FIG. 1 is provided with a decontamination gas generator 40 for decontaminating the inside in order to ensure the aseptic state of the chamber 10. Further, inside the chamber 10, a drug filling device 50 that operates in an aseptic state is placed.

The chamber 10 is made of a box made of a metal plate made of stainless steel, and is airtightly shielded from the external environment in which an operator (not shown) works, except for a restricted intake port and an exhaust port. A front door 11a and a back door 11b are provided on the front wall portion 10a (right side surface in the drawing) and the back wall portion 10b (left side surface in the drawing) of the chamber 10, respectively.

Above the inside of the chamber 10, a circulation fan 12 that circulates the air inside the chamber 10, a HEPA filter 13 that purifies the circulating air below the circulation fan 12, and a HEPA filter 13 that is below the chamber 10 and passes through the HEPA filter 13. A rectifying plate 14 for rectifying the generated air is provided.

On the other hand, below the inside of the chamber 10, a front partition wall 15a and a back partition wall 15b are arranged in parallel with both doors 11a and 11b inside the front door 11a and the back door 11b of the chamber 10, respectively. Both partition walls 15a and 15b are supported by both left and right wall portions (not shown) so as to be in contact with the left and right side wall portions (front surface and back surface in the illustrated direction) of the facing chamber 10.

Further, both partition walls 15a and 15b are provided with a constant space without abutting the lower end portions with the bottom wall portions 10c of the chamber 10 facing each other. Further, both partition walls 15a and 15b are supported by the straightening vane 14 so that the upper end portions thereof come into contact with the straightening vane 14 provided below the upper wall portion 10d of the facing chamber 10.

As described above, due to the two partition walls 15a and 15b provided inside the chamber 10, the internal space of the chamber 10 is the space between the two partition walls 15a and 15b (hereinafter referred to as the central space 16a) and the two partition walls 15a and 15b. It is divided into two spaces (hereinafter referred to as peripheral spaces 16b) between the front and rear doors 11a and 11b. Further, the upper space 16c is divided above the two peripheral spaces 16b.

The front door 11a and the back door 11b provided on the front wall portion 10a and the back wall portion 10b of the chamber 10 are provided with transparent glass windows 17a and 17b, respectively, and the front wall portion 10a and the back wall portion 10b are provided with transparent glass windows 17a and 17b, respectively. The front partition 15a and the back partition 15b provided in parallel are also provided with transparent glass windows 17c and 17d. As a result, the operator standing on the front surface or the back surface of the chamber 10 can visually recognize the inside of the chamber 10 through the glass windows 17a, 17b, 17c, 17d provided on the doors 11a, 11b and the partition walls 15a, 15b. can do.

Two working openings 18a are provided to communicate the outside and the internal space 16a of the chamber 10 via the front door 11a and the front partition wall 15a. Further, two working openings 18b are provided to communicate the outside and the internal space 16a of the chamber 10 via the back door 11b and the back partition wall 15b. The base ends of the resin gloves 19a and 19b are airtightly attached to the working openings 18a and 18b by a mounting frame (not shown), and the tip thereof is inserted into the central space 16a.

The air supply mechanism 20 includes an air supply blower 21 for supplying outside air into the chamber 10, an air supply filter unit 22 for filtering the air supplied from the air supply blower 21, and a damper 23. It is equipped with. On the other hand, the exhaust mechanism 30 includes an exhaust blower 31 for exhausting the air in the chamber 10 to the outside, an exhaust filter unit 32 for filtering the air exhausted from the exhaust blower 31, and a damper 33. It is equipped with.

These air supply mechanism 20 and exhaust mechanism 30 maintain the air pressure in the chamber 10 to be more positive than the external environment, or are also used for aeration after decontamination, in addition to supplying and exhausting air into the chamber 10. Will be done. Inside the chamber 10 configured in this way, the air in the upper space 16c is circulated by the circulation fan 12, and the air blown from the circulation fan 12 is cleaned by the HEPA filter 13 and is centrally passed through the straightening vane 14. It flows through the space 16a as a laminar flow from above to below. Further, the air flowing below the central space 16a circulates in the upper space 16c via the peripheral space 16b.

The decontamination gas generator 40 is used in the decontamination work of decontaminating the inside of the chamber 10 to ensure an aseptic state. The decontamination gas generator 40 includes a storage tank for hydrogen peroxide solution (not shown) and a vaporizer 41 that vaporizes the hydrogen peroxide solution to generate hydrogen peroxide gas containing water vapor. In the decontamination work for decontaminating the inside of the chamber 10, hydrogen peroxide gas (decontamination gas) generated in the vaporizer 41 is supplied from the upper wall portion 10d of the chamber 10 to the upper space 16c via the introduction pipe 42. Then, the circulation fan 12 circulates in the chamber 10.

The pharmaceutical filling device 50 is given as an example of the "working device" referred to in the present invention. In the present embodiment, the device for filling a container with a drug may be automatic or manual. Further, in the present invention, the working device is not limited to the drug filling device, but may be a crushing device, a mixing device, a measuring device, a processing device, or the like.

Next, in the isolator device configured as described above, the lighting system according to the present embodiment will be described. The lighting system according to the present invention has a lighting means and a control means. The lighting means has a plurality of color tones of lighting. Here, the plurality of color tone lighting means that the lighting has a working color tone lighting and at least one color tone lighting different from the working color tone lighting. The lighting of this different color tone is a lighting for notifying the operator of a warning, a warning, or some information, unlike the lighting during normal work. Hereinafter, the lighting of the color tone for work is referred to as a work lighting lamp, and the lighting of the color tone for warning or alerting is referred to as a notification lighting lamp.

Here, the "color tone" is, according to the 6th edition of Kojien (Iwanami Shoten), "the tone of the intensity and shade of color. Iroai." Therefore, in the present invention, the term "color tone" refers to the tone of strength and shade of all colors (including not only chromatic colors but also achromatic colors) represented by the three attributes of color (hue, lightness, and saturation). It shall mean any color including.

On the other hand, the control means controls the lighting means to change the color tone of the lighting, hereinafter referred to as a control device. This control device may be a switch or the like that independently switches between a work lighting lamp and a notification lighting lamp, or may be an automatic control device such as a microcomputer having a control circuit. Further, the control device may be provided with various sensors, arithmetic circuits, and the like. Although this control device is not shown in FIG. 1, it may be installed at a position away from the isolator device 1, or it may be housed in the gantry 2 in the same manner as the electrical equipment and machine room (not shown) of the isolator device 1. It may be touched.

In the present embodiment, in FIG. 1, the lighting system 60 mounted on the isolator device 1 includes work lighting lamps 61a and 61b, notification lighting lamps 62a and 62b, hydrogen peroxide gas concentration sensor 63, and pressure sensor 64. It includes an area sensor 65, a humidity sensor 66, and a control device (not shown). The lighting system according to the present invention does not have to include all of these elements, and may include a lighting lamp and a control device and combine other elements according to the purpose.

In FIG. 1, the work lighting lamps 61a and 61b are arranged in the space between the HEPA filter 13 and the straightening vane 14. The arrangement positions of the work lighting lamps 61a and 61b are not limited to this, and may be arranged at other positions in the chamber 10. The work lighting lamps 61a and 61b are lighting for the worker to work in the chamber 10 of the isolator device 1 via the gloves 19a and 19b, and the type is not particularly limited. For example, the color tone, the illuminance, and the like can be appropriately selected depending on the size of the chamber 10, the type of work, and the like. In this embodiment, two white fluorescent tubes are used. The work lighting lamps 61a and 61b may be turned on and off by the control device.

In FIG. 1, the notification lighting lamps 62a and 62b are arranged at different positions. One of the notification lighting lamps 62a is arranged at the same position as the work lighting lamps 61a and 61b in the space between the HEPA filter 13 and the straightening vane 14. Further, the other notification lighting lamp 62b is arranged above the back partition wall 15b of the central space 16a. The arrangement positions of the notification lighting lamps 62a and 62b are not limited to these, and other positions in the chamber 10 if the environment inside the work room can be easily visually recognized from the inside or the outside of the work room. It may be arranged in.

Further, in the present embodiment, the two notification lighting lamps 62a and 62b are arranged at different positions, but two or more notification lighting lamps may be arranged at the same position. Further, in the present embodiment, two notification lighting lamps are adopted, but the present invention is not limited to this, and only one or three or more notification lighting lamps may be adopted. When one notification lighting lamp is adopted, one lighting lamp may express a single color tone or may express a plurality of color tones. Further, when two or more notification lighting lamps are adopted, each of them expresses a single color tone, and a plurality of lighting lamps may express a plurality of color tones.

These notification lighting lamps 62a and 62b are lights for notifying the operator in the external environment of the isolator device 1 of the state in the chamber 10. Therefore, the lighting lamp has a color tone different from that of the white lighting used at the time of work, and may be a lighting lamp that changes to a plurality of color tones as described above. In this embodiment, an LED lamp capable of changing the color tone by RGB is adopted. By adopting this LED lamp, it is possible to express a plurality of or many color tones with one or a small number of lighting lamps. It should be noted that the present invention is not limited to the LED lamp capable of changing the color tone, and a plurality of single light LED lamps or fluorescent tubes may be adopted.

The hydrogen peroxide gas concentration sensor 63 inserts the sensor main body into the central space 16a from the bottom wall portion 10c of the chamber 10 and detects the hydrogen peroxide gas concentration inside the chamber 10 during the decontamination work. In the decontamination work in the chamber 10, the hydrogen peroxide gas concentration sensor 63 is the concentration of the hydrogen peroxide gas introduced into the chamber 10 from the decontamination gas generator 40 in the decontamination step, and the chamber in the aeration step. The decreasing concentration of hydrogen peroxide gas in 10 is sequentially detected and information is transmitted to the control device. Therefore, it is possible to notify the operator of the concentration of hydrogen peroxide gas in the chamber 10 and give a warning or alert.

The measurement principle of the hydrogen peroxide gas concentration sensor 63 includes various methods such as an ultraviolet excitation fluorescence method (enzyme catalyst removal method peroxidation reaction), but the sensor model and measurement principle are not particularly limited. An isolator device suitable for decontamination work may be appropriately adopted.

Further, although the hydrogen peroxide gas concentration sensor is adopted in the present embodiment, an operation sensor for detecting the operating state of the decontamination gas generator 40 may be adopted instead of the hydrogen peroxide gas concentration sensor. This operation sensor detects the operating state of the decontamination gas generator 40 and transmits information to the control device. Therefore, it is possible to notify the operator that the hydrogen peroxide gas is supplied into the chamber 10 and give a warning or alert. When the operation sensor is adopted, the supply of hydrogen peroxide gas in the decontamination step can be detected, but the change in the concentration of hydrogen peroxide gas in the chamber 10 cannot be sequentially detected.

The pressure sensor 64 sequentially detects the pressure inside the chamber 10 and transmits information to the control device via the pipe 64a led out from the bottom wall portion 10c of the chamber 10. The pressure sensor 64 is used in the airtightness test in the chamber 10 or when detecting that the airtightness in the chamber 10 is destroyed while working with the isolator device. The airtightness test will be described later. Therefore, it is possible to notify the operator that the airtightness in the chamber 10 has been destroyed and give a warning or alert.

The measurement principle of the pressure sensor 64 includes various types such as a Bourdon tube pressure gauge, a diaphragm pressure gauge, a bellows pressure gauge, and a liquid column pressure gauge, but the model of the sensor and the measurement principle are not particularly limited. An isolator device suitable for the airtightness test may be appropriately adopted.

The area sensor 65 is arranged at the position of the glove 19a from the front partition wall 15a of the chamber 10 toward the inside of the central space 16a. By adjusting the position of the area sensor 65 to the arm portion of the glove 19a, it is detected when the operator puts the arm in the glove 19a and information is transmitted to the control device. Further, by adjusting the position of the area sensor 65 in the vicinity of the drug filling device 50, it is detected when the hand inserted into the glove 19a is brought close to the drug filling device 50 operated by the operator, and information is sent to the control device. Send. Therefore, it is possible to notify the worker that he / she is approaching the operating medicine filling device 50 and give a warning or alert.

The measurement principle of the area sensor 65 is various, such as a photoelectric sensor, but the model and measurement principle of the sensor are not particularly limited, and if a sensor suitable for work in the isolator device is appropriately adopted. good.

Further, in the present embodiment, the area sensor 65 is adopted for detecting when the operator brings the glove 19a close to the drug filling device 50, but instead of this, an operation sensor for detecting the operating state of the drug filling device 50 is adopted. You may try to do it. This operation sensor detects the operating state of the drug filling device 50 and transmits information to the control device. Therefore, it is possible to notify the worker that the drug filling device 50 is operating or that the working device is in an abnormal state, and give a warning or alert.

The humidity sensor 66 inserts the sensor main body from the back wall portion 10b of the chamber 10 into the upper space 16c, and the humidity in the chamber 10 during the humidity control step during the decontamination work or the work in the isolator device. Is sequentially detected and information is transmitted to the control device. Therefore, it is possible to notify the operator of the humidity in the chamber 10 and alert or notify the operator.

The measurement principle of the humidity sensor 66 includes various types such as a resistance type and a capacitance type polymer sensor and a ceramic sensor, but the sensor model and the measurement principle are not particularly limited, and the isolator device is not particularly limited. Anything suitable for measuring the humidity inside may be appropriately adopted.

The control device (not shown) controls the lighting means (working lighting lamps 61a, 61b, and notification lighting lamps 62a, 62b) according to a preset program in response to the information from each of the above sensors. Change the color tone of the lighting. The control device may not only change the color tone of the lighting but also control the lighting means to make the lighting blink. The specific correspondence with each sensor will be described later.

In this way, the color tone of the lighting is different from the color tone during normal work, so that the operator can be notified of a warning, a warning, or some information. Since the notification lighting lamps 62a and 62b are arranged in the chamber 10 and irradiate all the wall surfaces in the chamber 10, what kind of state the inside of the chamber 10 can be seen by an operator outside the chamber 10. It can be easily visually recognized from the position.

Next, various operations performed by using the isolator device and the lighting system configured as described above will be described by way of examples. The present invention is not limited to the following examples.

In this embodiment, the lighting system 60 is effectively utilized in a series of operations in the isolator device. This embodiment relates to an airtightness inspection work for confirming the airtightness in the chamber 10, a decontamination work for ensuring the aseptic state in the chamber 10, and a work in the chamber 10 in the aseptic state. Each work and the effectiveness of the lighting system 60 will be described below.

1. 1. Airtightness inspection work FIG. 2 is a diagram showing a color tone change due to the lighting system with respect to the flowchart of the airtightness inspection work in this embodiment. In FIG. 1, the airtightness inspection work is started from a state in which both doors 11a and 11b of the isolator device 1 are closed and both dampers 23 and 33 of the air supply / exhaust mechanisms 20 and 30 are closed.

In step S1 of FIG. 2, the pressure in the chamber 10 is pressurized to a positive pressure rather than the external environment. Specifically, the damper 23 of the air supply mechanism 20 is opened to drive the blower 21 to supply air to the inside of the chamber 10. At this time, the inside of the chamber 10 is illuminated with white light by the work lighting lamps 61a and 61b by the control device of the lighting system 60. Further, the pressure sensor 64 operates to transmit information on the internal pressure of the chamber 10 to the control device.

Next, in step S2, when the internal pressure of the chamber 10 reaches a preset pressure in the airtightness inspection operation, information from the pressure sensor 64 is transmitted to the control device. As a result, the control device blinks the white light of the work lighting lamps 61a and 61b in order to notify that the internal pressure of the chamber 10 has reached a predetermined pressure. As a result, the operator outside the isolator device 1 can easily visually recognize that the internal pressure of the chamber 10 has reached a predetermined pressure through the glass windows 17a, 17b, 17c, 17d of the isolator device 1. Can be done.

Next, in step S3, the pressurization in the chamber 10 is stopped, and the measurement of the internal pressure by the pressure sensor 64 is continued. These measured values are sequentially transmitted from the pressure sensor 64 to the control device. In this embodiment, the notification lighting lamps 62a and 62b are turned on by the control device, the color tone is controlled to be yellow, and the inside of the chamber 10 is illuminated with yellow light. As a result, all the wall surfaces inside the chamber 10 are irradiated with yellow light, so that the operator outside the chamber 10 can easily visually recognize that the inside of the chamber 10 is measuring the change in internal pressure. Can be done.

Next, in step S4, the decompression speed of the internal pressure by the control device is calculated while measuring the internal pressure of the chamber 10 by the pressure sensor 64. The calculation of the depressurization speed is indicated by the pressure change (decompression amount) per unit time according to the program preset in the control device. In addition, a limit value (set value) for the decompression rate is set for each isolator device that performs the airtightness test, and if a large decompression rate exceeding this set value is calculated, the control device will use this. Is judged as the destruction of airtightness.

If it is determined that the airtightness is destroyed, the control device controls the notification lighting lamps 62a and 62b to change the color tone to red and blink it to issue a warning. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing red light, so that the operator outside the chamber 10 can easily visually recognize that the airtightness of the chamber 10 is in a broken state. can.

On the other hand, if the destruction of the airtightness is not detected within the preset time while repeating the calculation of the decompression speed in step S4, the passage of the predetermined time is confirmed in step S5. If the destruction of the airtightness is not detected until the passage of the predetermined time is confirmed in step S5, the inside of the chamber 10 is illuminated with yellow light.

When the passage of the predetermined time is confirmed in step S5, the airtightness test is terminated in step S6. When the airtightness inspection is completed, the control device controls the notification lighting lamps 62a and 62b to change the notification to a yellow flashing light for notification. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing yellow light, so that the operator outside the chamber 10 can easily visually recognize that the airtightness inspection of the chamber 10 has been completed. ..

2. 2. Decontamination work FIG. 3 is a diagram showing a color tone change due to a lighting system for a flow chart of a humidity control process and a decontamination process of the decontamination work in this embodiment. Further, FIG. 4 is a diagram showing a color tone change due to the lighting system with respect to the flowchart of the aeration process of the decontamination work in this embodiment. For the isolator device 1 in which the destruction of the airtightness is not detected in the above-mentioned airtightness inspection work, the humidity inside the chamber 10 is controlled in the humidity control step prior to the decontamination step.

In step S7 of FIG. 3, the damper 23 of the air supply mechanism 20 is adjusted to drive the blower 21 to supply air to the inside of the chamber 10, and the damper 33 of the exhaust mechanism 30 is adjusted to drive the blower 31 to drive the chamber. Exhaust the air inside 10. Together with this air supply and exhaust, the circulation fan 12 in the chamber 10 is driven. In this state, the humidity inside the chamber 10 is adjusted to a preset humidity suitable for decontamination. The humidification into the chamber 10 may be performed via the air supply mechanism 20 or may be performed by a humidifier provided separately.

At this time, the control device of the lighting system 60 controls the notification lighting lamps 62a and 62b to change the color tone to dark blue. As a result, all the wall surfaces in the chamber 10 are irradiated with dark blue light, so that the operator outside the chamber 10 can easily visually recognize that the inside of the chamber 10 is in the process of humidity control. .. Further, the humidity sensor 66 is activated to transmit information on the humidity in the chamber 10 to the control device.

Next, when the humidity in the chamber 10 reaches a preset humidity, the humidity control step is terminated in step S8. At this time, the control device controls the notification lighting lamps 62a and 62b to change the notification to a dark blue blinking light for notification. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing light of dark blue, so that the operator outside the chamber 10 can easily visually recognize that the humidity control process of the chamber 10 is completed. ..

Upon notification of the end of the humidity control process, the humidity control is stopped and the air supply mechanism 20 and the exhaust mechanism 30 are closed in preparation for the subsequent decontamination process. Next, the decontamination process is started. First, in step S9, the decontamination gas is supplied into the chamber 10. In this example, hydrogen peroxide gas was adopted as the decontamination gas.

The hydrogen peroxide gas was supplied by the decontamination gas generator 40. The hydrogen peroxide solution was vaporized by the vaporizer 41 of the decontamination gas generator 40 to generate hydrogen peroxide gas containing water vapor, which was supplied from the upper wall portion 10d of the chamber 10 to the upper space 16c via the introduction pipe 42. .. At this time, the circulation fan 12 was driven to circulate the hydrogen peroxide gas in the chamber 10.

At this time, the control device of the lighting system 60 controls the notification lighting lamps 62a and 62b to change the color tone to purple to give a warning. As a result, all the wall surfaces inside the chamber 10 are irradiated with purple light, so that the operator outside the chamber 10 can easily visually recognize that the inside of the chamber 10 is being decontaminated. .. Further, the concentration sensor 63 is activated to transmit information regarding the concentration of hydrogen peroxide gas in the chamber 10 to the control device.

Next, in step S10, the measurement of the hydrogen peroxide gas concentration by the concentration sensor 63 is continued while supplying the hydrogen peroxide gas into the chamber 10. These measured values are sequentially transmitted from the concentration sensor 63 to the control device.

Next, in step S11, when the concentration of hydrogen peroxide gas in the chamber 10 reaches a concentration preset in the decontamination operation, information from the concentration sensor 63 is transmitted to the control device. As a result, the control device blinks the purple light of the notification lighting lamps 62a and 62b in order to notify that the concentration of hydrogen peroxide gas in the chamber 10 has reached a predetermined concentration suitable for decontamination. As a result, the operator outside the isolator device 1 can easily visually recognize that the hydrogen peroxide gas concentration in the chamber 10 has reached a predetermined concentration.

When the concentration of hydrogen peroxide gas in the chamber 10 reaches a predetermined concentration, the decontamination gas generator 40 is stopped and the supply of hydrogen peroxide gas is terminated. In this state, leave it for a predetermined time to complete the decontamination. Next, in step S12, the passage of a predetermined time is confirmed. Until the lapse of a predetermined time is confirmed in step S12, the inside of the chamber 10 is illuminated with purple light to notify that decontamination is in progress.

When the passage of the predetermined time is confirmed in step S12, the decontamination step is terminated in step S13. When the decontamination step is completed, the control device controls the notification lighting lamps 62a and 62b to change the notification to a purple flashing light for notification. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing purple light, so that the operator outside the chamber 10 can easily visually recognize that the decontamination process of the chamber 10 has been completed. ..

Upon notification of the end of the decontamination step, the aeration step is started in step S14 of FIG. At this time, the control device of the lighting system 60 controls the notification lighting lamps 62a and 62b to change the color tone to dark green to give a warning. As a result, all the wall surfaces in the chamber 10 are irradiated with dark green light, so that the operator outside the chamber 10 can easily visually recognize that the inside of the chamber 10 enters the aeration process. Further, the concentration sensor 63 is activated to transmit information regarding the concentration of hydrogen peroxide gas in the chamber 10 to the control device.

Next, in step S15, the supply / exhaust of clean air (diluting air) is started. Specifically, the air supply mechanism 20 is driven to introduce clean air (diluting air) into the chamber 10 to dilute the hydrogen peroxide gas in the chamber 10. Further, the exhaust mechanism 30 is driven to exhaust the hydrogen peroxide gas in the chamber 10 and the diluting air to the outside. By continuing these, all the hydrogen peroxide gas in the chamber 10 is exhausted to the outside.

At this time, the control device controls the notification lighting lamps 62a and 62b to blink the dark green light of the notification lighting lamps 62a and 62b. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing light of dark green, so that the operator outside the chamber 10 can easily visually recognize that the inside of the chamber 10 is being aerated. can. Further, the concentration sensor 63 is activated to transmit information regarding the concentration of hydrogen peroxide gas in the chamber 10 to the control device.

Next, in step S16, the measurement of the hydrogen peroxide gas concentration by the concentration sensor 63 is continued while continuing the supply / exhaust of clean air (diluting air) into the chamber 10. These measured values are sequentially transmitted from the concentration sensor 63 to the control device. In this embodiment, the color tones of the notification lighting lamps 62a and 62b are changed from dark green flashing light (corresponding to high-concentration hydrogen peroxide gas) to light green flashing light (low) according to a program preset in the control device. Change the gradation to (corresponding to the concentration of hydrogen peroxide gas).

In this way, when the hydrogen peroxide gas in the chamber 10 is diluted and the concentration reaches the detection limit of the concentration sensor 63, the aeration step is terminated in step S18. When the aeration step is completed, the control device controls the notification lighting lamps 62a and 62b to change the notification to a blinking blue light for notification. This blue flashing light notification lasts for a few minutes. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing blue light for several minutes, so that the operator outside the chamber 10 has completed the aeration process of the chamber 10 and ensured an aseptic state. Can be easily visually recognized.

Upon notification of the end of the aeration process, the air supply mechanism 20 and the exhaust mechanism 30 are switched to normal operation. Next, in step S19, the control device turns off the notification lighting lamps 62a and 62b, turns on the white light of the work lighting lamps 61a and 61b, and the aseptic state of the chamber 10 is ensured so that the work can be performed. Notify that there is.

3. 3. Working in a sterile chamber FIG. 5 is a diagram showing a color change due to a lighting system for working in a sterile chamber in this embodiment. In the above-mentioned isolator device 1 in which the aseptic state is ensured, an outside worker starts the work through the glove.

In step S19 of FIG. 5, the inside of the chamber 10 is in a aseptic state, and the white light of the work lighting lamps 61a and 61b is lit by the control device of the lighting system 60.

Next, in step S20, the work difference outside the chamber 10 starts work via the gloves 19a and 19b. At this time, the inside of the chamber 10 is illuminated with white light by the work lighting lamps 61a and 61b by the control device. In addition, the pressure sensor 64 is activated to monitor the destruction of airtightness during work. Further, a drug filling device 50 is driven inside the chamber 10, and an operation sensor (not shown) for detecting the driving state of the drug filling device 50 and an area sensor 65 are operated in the vicinity of the drug filling device 50. is doing. The operation of each sensor and the change in color tone due to the lighting system will be described below.

First, in step S21, the operation of the pressure sensor 64 is the same as in the case of the above-mentioned airtightness test. Here, both the air supply mechanism 20 and the exhaust mechanism 30 are in a normal operating state, and the internal pressure of the chamber 10 is kept constant. Again, the controller is calculating the decompression rate of the internal pressure. However, if some abnormality occurs during the work and the airtightness is destroyed, the control device calculates a large decompression speed exceeding the set value based on the information from the pressure sensor 64, and determines that the airtightness is destroyed.

When it is determined that the airtightness is destroyed, the control device controls the notification lighting lamps 62a and 62b to turn on the color tone in red and blink it to issue a warning. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing red light, so that the operator working from the outside of the chamber 10 can easily visually recognize that the airtightness of the chamber 10 is in a broken state. can do.

On the other hand, in step S22, when the predetermined work is completed without detecting the destruction of the airtightness during the work while repeating the calculation of the decompression speed, the work is terminated in step S24. If no airtightness disruption is detected during work, the chamber 10 is illuminated with working white light.

Next, in step S22, the lighting system 40 operates in the sense of calling attention when the operator's hand wearing the glove 19a approaches the vicinity of the operating medicine filling device 50 by the action of the area sensor 65. Specifically, the control device controls the notification lighting lamps 62a and 62b to turn on the color tone in orange and blink it to call attention. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing orange light, so that the worker working from the outside of the chamber 10 approaches the vicinity of the drug filling device 50 in which his / her hand operates. It can be easily visually recognized.

Next, in step S23, when the operation of the drug filling device 50 becomes abnormal due to the action of the operation sensor (not shown), the lighting system 40 operates in the sense of issuing a warning. Specifically, the control device controls the notification lighting lamps 62a and 62b to turn on the color tone in magenta and blink it to give a warning. As a result, all the wall surfaces in the chamber 10 are irradiated with the flashing light of magenta, so that the worker working from the outside of the chamber 10 has some abnormality in the operation of the drug filling device 50. It can be easily visually recognized.

As described above, in the present invention, in a work room that can be airtightly shielded from the external environment, a lighting system that can easily visually recognize the internal state of the work room from any position with a simple configuration. Can be provided.

In carrying out the present invention, not only the above-described embodiment but also various modifications as follows can be mentioned.
(1) In the above embodiment, the lighting system is arranged in the chamber of the isolator for explanation, but the present invention is not limited to this, and the lighting system is not limited to the external environment such as a clean bench, RABS (access restricted barrier system), and a clean room. The lighting system can be applied to any work room as long as it has an airtightly shielded internal environment.
(2) In the above embodiment, each situation is changed to illuminate or blink in a different color tone according to the situation in the chamber of the isolator, but the present invention is not limited to this, and only when a danger or the like is detected. You may want to issue a warning.
(3) In the above embodiment, the concentration of hydrogen peroxide gas in the chamber of the isolator is detected to change the color tone of the lighting by gradation, but the present invention is not limited to this, and the decontamination gas generator is provided with an operation sensor. , The warning may be issued only when hydrogen peroxide gas is supplied to the chamber.
(4) In the above embodiment, when an area sensor is arranged in the vicinity of the drug filling device arranged in the chamber of the isolator and the worker brings the hand inserted into the glove close to the operating device. Although it is intended to call attention, it is not limited to this, and it may be used to call attention when the worker inserts his / her arm into the glove.
(5) In the above embodiment, in the humidity control step in the chamber of the isolator, only the start and completion of humidity control are notified, but the present invention is not limited to this, and the humidity value detected by the humidity sensor is used. At the same time, the humidity state that changes during the humidity control work may be sequentially notified.
(6) In the above embodiment, the LED lamp capable of changing the color tone by RGB is adopted in the lighting system, but the present invention is not limited to this, and a plurality of single light LED lamps or fluorescent tubes are adopted. You may do it.
(7) In the above embodiment, the lighting system is arranged and described in the chamber of the isolator, but the present invention is not limited to this, and in an isolator provided with one or two or more pass boxes, the chamber and each are described. A notification lighting lamp may be provided in each pass box so that the color tone of the lighting in the chamber and each pass box can be changed independently.
(8) In the above embodiment, the lighting system is arranged and described in a sterile isolator that works in a sterile environment, but the present invention is not limited to this, and is not limited to this, but is a containment isolator that handles environmental pollutants inside the chamber. A lighting system may be arranged to warn workers outside the isolator that environmental pollutants are present inside the chamber and are in a dangerous condition.

1 ... Isolator device, 2 ... Stand, 3 ... Isolator body,
10 ... Chamber, 10a, 10b, 10c, 10d ... Wall,
11a, 11b ... door, 12 ... circulation fan, 13 ... HEPA filter, 14 ... rectifying plate,
15a, 15b ... partition wall, 16a, 16b, 16c ... space,
17a, 17b, 17c, 17d ... Glass window, 18a, 18b ... Working opening,
19a, 19b ... Gloves, 20 ... Air supply mechanism, 30 ... Exhaust mechanism,
21, 31 ... Blower, 22, 32 ... Filter unit, 23, 33 ... Damper,
40 ... Decontamination gas generator, 41 ... Vaporizer, 42 ... Introduction piping, 50 ... Pharmaceutical filling device,
60 ... Lighting system, 61a, 61b ... Work lighting lamp,
62a, 62b ... Notification lighting lamp, 63 ... Hydrogen peroxide gas concentration sensor,
64 ... pressure sensor, 65 ... area sensor, 66 ... humidity sensor.

Claims (10)

A lighting system that illuminates the inside of a work room that can be airtightly shielded from the external environment.
It has a lighting means having a work lighting lamp and a notification lighting lamp and having a plurality of color tones, and a control means for controlling the lighting means to change the color tone of the lighting.
By changing the color tone of the notification lighting lamp by the control means and turning on the lighting of the color tone corresponding to the internal situation of the work room inside the work room.
A lighting system characterized in that the environment inside the work room can be easily visually recognized from the outside of the work room through a viewing window provided on the wall of the work room. In the decontamination work inside the work room
During the decontamination process of decontaminating the inside of the work room using a supply means that supplies decontamination gas.
The control means includes an operation sensor that detects an operation state of the supply means.
When the operation sensor detects the operating state of the supply means, the control means controls the lighting means to change the color tone of the notification lighting lamp to a different color tone according to each operating state. The lighting system according to claim 1. In the decontamination work inside the work room
A decontamination process for decontaminating the inside of the work room using a supply means for supplying decontamination gas, and
After the decontamination step, the air supply means for supplying the diluting air for removing the decontamination gas filled inside the working room, and the decontaminating gas and the diluting air inside the working room are discharged. During the aeration process of aerating the inside of the work room using an exhaust means
The control means includes a concentration sensor that detects the concentration of the decontamination gas inside the work room.
When the concentration sensor detects the concentration of the decontamination gas inside the work room, the control means controls the lighting means to change the color tone of the notification lighting lamp for decontamination inside the work room. The lighting system according to claim 1, wherein the lighting system is changed to a different color tone according to a change in gas concentration . In the decontamination work inside the work room
A humidity control means is used before the decontamination step to adjust the humidity inside the work room. During the humidity control step, the control means includes a humidity sensor for detecting the humidity inside the work room.
When the humidity sensor detects the humidity inside the work room, the control means controls the lighting means to change the color tone of the notification lighting lamp according to the change in the humidity inside the work room. The lighting system according to claim 2 or 3 , wherein the lighting system is changed to. In the decontamination work inside the work room and the work in an aseptic state,
According to the state of each process during the humidity control process, humidity control completion, decontamination gas supply, decontamination gas supply completion, decontamination, aeration, aeration completion, and aseptic operation.
The lighting system according to claim 4, wherein the control means controls the lighting means to change the color tone of the notification lighting lamp to a different color tone according to the state of each process . In the airtightness inspection work that inspects or manages the airtightness inside the work room that is in a positive pressure state compared to the external environment.
The control means includes a pressure sensor that detects the pressure inside the work room.
The control means calculates the decompression speed inside the work room based on the information from the pressure sensor, and when the decompression speed exceeds a predetermined value, the airtightness of the work room is in a broken state . The lighting system according to any one of claims 1 to 5, further comprising controlling the lighting means to change the color tone of the notification lighting lamp to a color tone that warns of an abnormal situation . The working chamber is a chamber of an isolator, and has a working device inside the chamber.
The control means includes an operation sensor that detects an operation state of the work device.
When the operation sensor detects the operating state of the working device, the control means controls the lighting means to change the color tone of the notification lighting lamp to a different color tone according to the operating state of the working device. The lighting system according to claim 1. The isolator has gloves for external workers to work inside the chamber.
The control means includes an area sensor that detects the position of the glove.
When the area sensor detects when the worker puts his / her arm in the glove or when the glove is in the vicinity of the working device, the control means controls the lighting means to perform the notification lighting. The lighting system according to claim 7, wherein the color tone of the lamp is changed to call attention to an operator . The working room is an isolator chamber.
In addition to the main body chamber, the isolator includes one or more pass boxes for putting articles in and out of the chamber.
The chamber and each pass box have independent lighting means.
The control means according to any one of claims 1 to 8, wherein the control means controls the lighting means to change the color tone of the notification lighting lamp of the chamber and each pass box simultaneously or separately. Lighting system. The one according to any one of claims 1 to 9, wherein the control means controls the lighting means to make a change due to blinking of the lighting in addition to the change due to the color tone of the notification lighting lamp . Lighting system.

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