JP7085313B2 - Blood purification device - Google Patents

Description

The present invention relates to a blood purification device.

Blood purification treatments such as dialysis treatment and plasma exchange treatment are usually performed using a blood purification device. For example, blood purifiers that perform dialysis treatment include blood purifiers consisting of hollow filament modules, tubes and pumps for sending blood to blood purifiers, tubes, metering chambers and valves for sending dialysate to blood purifiers. It is composed of multiple elements such as a filter for removing unnecessary substances from the dialysate. These elements are housed in the housing of the blood purification device (see Patent Document 1).

The housing of a conventional blood purification device has a structure in which columns are erected at the four corners of the housing to ensure strength, and horizontal partition plates are arranged inside those columns, and each stage partitioned by the partition plate. Each element was housed inside.

JP-A-2015-93166.

However, in the above-mentioned blood purification device, since the frontage for the user to access the inside of each stage is narrowed, it is difficult for the user to access when maintaining the element, and it is difficult to check the arrangement and connection status of the element. Maintenance is not good.

The present invention has been made in view of the above points, and one of the objects thereof is to realize a blood purification device having a housing having a good maintainability while ensuring strength.

As a result of diligent studies, the present inventors have solved the above problem by making the housing having two outer vertical plates facing each other and an inner vertical plate connecting the two outer vertical plates to each other. We found what we could do and came to complete the present invention.

That is, the present invention includes the following aspects.
(1) A housing and a plurality of elements for performing blood purification treatment are provided, and the housing is arranged between two outer vertical plates facing each other and the two outer vertical plates. A blood purification device comprising: an inner vertical plate connecting the outer vertical plates to each other, wherein at least one of the plurality of elements is attached to at least one of the inner vertical plate or the outer vertical plate. The "element" includes various devices, devices, members and the like for performing blood purification treatment.
(2) An internal space surrounded by the inner vertical plate and the outer vertical plate is formed on both sides of the inner vertical plate, and the housing has a door that can open and close the inner space (1). The described blood purification device.
(3) The blood purification device according to (2), wherein the door is rotatably configured around a vertical axis provided on the back surface side of the housing.
(4) The blood purification device according to (2) or (3), wherein a control unit is provided on the housing, and the door extends to the side surface of the control unit.
(5) The first outer vertical plate of the two outer vertical plates is arranged on the front surface of the housing, and the second outer vertical plate is arranged on the back surface of the housing, (1) to (4). ) The blood purification device according to any one of.
(6) The plurality of elements include a liquid storage container for storing a liquid used in blood purification treatment, and the liquid storage container can be placed on the outer surface of the second outer vertical plate. The blood purification device according to (5), which is provided with a container.
(7) The hollow fiber membrane module is included in the plurality of elements, and the hollow fiber membrane module is attached to the outer surface of the second outer vertical plate, according to (5) or (6). Blood purification device.

According to the present invention, it is possible to realize a blood purification device having a housing with good maintainability while ensuring strength.

It is a perspective view which shows an example of a blood purification apparatus. It is a perspective view which shows an example of the housing in the state which the element is removed. FIG. 2 is a sectional view taken along the line YY of the housing of FIG. It is a perspective view which shows the side door of the housing with the element removed. It is a perspective view seen from the front side which shows an example of the housing with the element attached. It is a perspective view seen from the back side which shows an example of the housing which attached the element. It is explanatory drawing which shows the structural example of the element group of a blood purification apparatus.

Hereinafter, preferred embodiments of the present invention will be described with reference to the drawings. The same elements are designated by the same reference numerals, and duplicate description will be omitted. In addition, the positional relationship such as up, down, left, and right shall be based on the positional relationship shown in the drawings unless otherwise specified. Furthermore, the dimensional ratios in the drawings are not limited to the ratios shown. Further, the following embodiments are examples for explaining the present invention, and the present invention is not limited to this embodiment.

FIG. 1 is a diagram showing an outline of the configuration of the blood purification device 1 according to the present embodiment. The blood purification device 1 includes, for example, a housing 10, a side door 11, a front door 12, a trolley 13, an element group 14 composed of various elements for performing blood purification processing, a control unit 15, and the like. ..

The blood purification device 1 has an overall shape of a vertically long rectangular parallelepiped, a substantially rectangular parallelepiped housing 10 is installed on a carriage 13, and a substantially rectangular parallelepiped control unit 15 is installed on the housing 10. .. The front door 12 is provided on the front surface of the housing 10 (on the X direction side in FIG. 1), and the side doors 11 are provided on both left and right sides of the housing 10 and the control unit 15. The various elements of the element group 14 are attached to the housing 10, the front door 12, and the like.

The housing 10 is arranged between two outer vertical plates 30 and 31 facing each other and the two outer vertical plates 30 and 31 arranged in the front-rear direction as shown in FIG. 2, for example, and two outer sides. It has an inner vertical plate 32 that connects the vertical plates 30 and 31 to each other, a bottom plate 33, and a top plate 34.

The outer vertical plates 30 and 31 are formed in a vertically long substantially rectangular shape. The first outer vertical plate 30 is arranged on the front side (X direction side) of the housing 10, and the second outer vertical plate 31 is arranged on the back side (opposite side in the X direction) of the housing 10. There is. The first outer vertical plate 30 and the second outer vertical plate 31 are arranged parallel to each other.

The inner vertical plate 32 is formed in a vertically long substantially rectangular shape having substantially the same height as the outer vertical plates 30 and 31. As shown in FIG. 3, the inner vertical plate 32 connects the central portion of the first outer vertical plate 30 and the central portion of the second outer vertical plate 31. The inner vertical plate 32 is connected at right angles to the first outer vertical plate 30 and the second outer vertical plate 31. With this configuration, the outer vertical plates 30 and 31 and the inner vertical plate 32 are substantially H-shaped when viewed from above. Internal spaces S1 and S2 surrounded by the inner vertical plate 32 and the outer vertical plates 30 and 31 are formed on both the left and right sides of the inner vertical plate 32 of the housing 10. The vertical plates 30, 31, and 32 are appropriately provided with fixing members and holes for attaching the elements of the element group 14. The housing 10 is made of, for example, metal or resin.

As shown in FIGS. 1 and 4, the side door 11 is formed in a vertically long substantially rectangular shape covering the control unit 15 and the housing 10. The side door 11 can rotate around a vertical axis 11a provided at the rear end of the side surface of the housing 10 and the control unit 15. The side door 11 can open and close the internal spaces S1 and S2 by rotating.

As shown in FIG. 1, the front door 12 can rotate around a rotation axis provided at either one of the left and right ends of the front surface of the housing 10. Some elements such as a pump can be attached to the front door 12.

The control unit 15 is a computer, and can control the devices and devices of the element group 14 to realize the blood purification process by executing a program. The control unit 15 is provided with a display screen 40 on the front surface for displaying various information on the blood purification process. The display screen 40 can be used to make various settings for blood purification processing.

The blood purification device 1 has an element group 14 composed of a plurality of elements as shown in FIGS. 5 and 6, and each element of the element group 14 is attached to a housing 10, a front door 12, or the like.

The blood purification device 1 includes, for example, an element group 14 as shown in FIG. 7. The blood purifying device 1 includes, for example, a blood purifying device 50, a blood circuit 51, a dialysate circuit 52, and the like.

The blood purifier 50 is, for example, a hollow fiber membrane module having a hollow fiber membrane in a columnar module, and has a blood purifying membrane 60 inside.

The blood circuit 51 has a flow path composed of a soft tube. The blood circuit 51 includes, for example, a blood collection flow path 71 leading from the blood collection unit 70 to the primary side (inner region of the hollow fiber membrane) of the blood purification membrane 60 of the blood purifier 50, and the primary side of the blood purification membrane 60 of the blood purifier 50. It is provided with a blood return flow path 73 leading to the blood return portion 72. The blood collection channel 71 is provided with a blood pump 80 and a drip chamber 81. The blood return flow path 73 is provided with a drip chamber 90.

The dialysate circuit 52 includes, for example, a metering chamber 100, a first dialysate supply circuit 101, a second dialysate supply circuit 102, a first waste liquid circuit 103, a second waste liquid circuit 104, and water removal. It includes a circuit 105, a cleaning liquid supply circuit 106, and the like.

The metering chamber 100 includes a container 110 having a constant volume, and a partition wall 111 that separates the inside of the container 110 into a liquid supply chamber A and a waste liquid chamber B. The partition wall 111 is configured by, for example, a rubber diaphragm and is freely displaceable. In the metering chamber 100, the partition wall 111 is displaced due to the fluctuation of the internal pressures of the liquid supply chamber A and the waste liquid chamber B, and the volumes of the liquid supply chamber A and the waste liquid chamber B fluctuate. It becomes smaller.

The first dialysate supply circuit 101 stores the first flow path 120 leading from the external supply source of dialysis water (not shown) to the supply chamber A of the metering chamber 100, and the stock solution of the dialysate. It is provided with two storage containers 121 and 122, a second flow path 123 connecting the storage container 121 and the first flow path 120, and a third flow path 124 connecting the storage container 122 and the first flow path 120. ing. The first flow path 120, the second flow path 123, and the third flow path 124 are composed of a soft tube. The first flow path 120 is provided with a heater 125, a pump 126, an on-off valve 127, and the like. On-off valves 128, 129, etc. are provided in the second flow path 123 and the third flow path 124.

The second dialysate supply circuit 102 includes a fourth flow path 130 that leads from the liquid supply chamber A of the metering chamber 100 to the secondary side (outer region of the hollow fiber membrane) of the blood purification membrane 60 of the blood purifier 50. ing. The fourth flow path 130 is composed of a soft tube. The fourth flow path 130 is provided with an on-off valve 131, a liquid mixing device 132, a flow rate sensor 133, two filters 134, 135, and the like. The liquid mixing device 132 promotes mixing of dialysate (stock solution and dialysis water). The filters 134 and 135 are, for example, hollow fiber membrane modules for capturing endotoxin, which is an unnecessary substance.

The first waste liquid circuit 103 includes a fifth flow path 140 leading from the secondary side of the blood purification membrane 60 of the blood purifier 50 to the waste liquid chamber B of the metering chamber 100. The fifth flow path 140 is composed of a soft tube. The fifth flow path 140 is provided with a pump 141, an on-off valve 142, and the like.

The second waste liquid circuit 104 includes a sixth flow path 150 leading from the waste liquid chamber B of the metering chamber 100 to the external waste liquid portion. The sixth flow path 150 is composed of a soft tube. The sixth flow path 150 is provided with an on-off valve 151 and the like.

The water removal circuit 105 includes a seventh flow path 160 that bypasses the metering chamber 100 from the first waste liquid circuit 103 and leads to the second waste liquid circuit 104. The seventh flow path 160 is composed of a soft tube. A pump 161 or the like is provided in the seventh flow path 160.

The cleaning liquid supply circuit 106 sends two storage containers 170 and 171 for storing the undiluted solution of the cleaning liquid and an eighth flow path 172 for sending the undiluted solution of the storage containers 170 and 171 to the second flow path 123 and the third flow path 124. have. The eighth flow path 172 is composed of a soft tube. The eighth flow path 172 is provided with on-off valves 173, 174 and the like.

During the blood purification process of the dialysis treatment, the blood pump 80 operates and the patient's blood is supplied to the blood purifier 50 through the blood collection channel 71 of the blood circuit 51. Blood passes through the primary side of the blood purifying membrane 60 of the blood purifier 50 and then is returned to the patient through the blood return channel 73 of the blood circuit 51.

On the other hand, in the dialysate circuit 52, the dialysate is supplied and discharged to the secondary side of the blood purification membrane 60 of the blood purifier 50. First, in the first dialysate supply circuit 101, the pump 126 is operated, and the dialysate water whose temperature is adjusted by the heater 125 is mixed with the stock solution supplied from the storage containers 121 and 122 to generate a dialysate. The dialysate is supplied to the liquid supply chamber A of the metering chamber 100. Further, while the dialysate is filled in the liquid supply chamber A, the waste liquid in the waste liquid chamber B is drained to the outside through the second waste liquid circuit 104.

When the liquid supply chamber A is filled with the dialysate, the pump 141 causes the dialysate in the liquid supply chamber A to pass through the second dialysate supply circuit 102 to the secondary side of the blood purification membrane 60 of the blood purifier 50. Be supplied. The dialysate (waste liquid) that has passed through the secondary side of the blood purification membrane 60 is supplied to the waste liquid chamber B of the metering chamber 100 through the first waste liquid circuit 103. Further, the pump 161 supplies a part of the waste liquid of the first waste liquid circuit 103 to the second waste liquid circuit 104 through the water removal circuit 105. In this way, in the blood purifier 50, blood is supplied to the primary side of the blood purifying membrane 60, dialysate is supplied to the secondary side of the blood purifying membrane 60, and a predetermined unnecessary substance in the blood is dialyzed through the blood purifying membrane 60. It is discharged to the liquid side and the blood is purified.

Further, when cleaning the dialysate circuit 52, in the cleaning liquid supply circuit 106, the undiluted solution is supplied from the storage containers 170, 171 to the eighth flow path 172 to generate a cleaning liquid, and the cleaning liquid is used as the second flow path. It is supplied to 123, the third flow path 124, and the first dialysate supply circuit 101.

As described above, the element group 14 of the blood purification device 1 includes, for example, a blood purifier 50, a blood collection channel 71, a blood return channel 73, a blood pump 80, a drip chamber 81, a drip chamber 90, a metering chamber 100, and a first. Flow path 120, storage container 121, 122, second flow path 123, third flow path 124, heater 125, pump 126, on-off valve 127, on-off valve 128, 129, fourth flow path 130, on-off valve 131. , Liquid mixing device 132, flow rate sensor 133, filters 134, 135, fifth flow path 140, pump 141, on-off valve 142, sixth flow path 150, on-off valve 151, seventh flow path 160, pump 161. It is composed of elements such as a storage container 170, 171 and an eighth flow path 172, an on-off valve 173, and 174.

As shown in FIGS. 5 and 6, each element of the element group 14 is attached to the outer vertical plates 30 and 31 and the inner vertical plate 32 of the housing 10. For example, as shown in FIG. 6, the metering chamber 100 is attached to the inner vertical plate 32. The filters 134 and 135 are attached to the outer surface of the second outer vertical plate 31. Further, a mounting table 190 is provided on the outer surface of the second outer vertical plate 31, and the cleaning liquid storage containers 170 and 171 are placed on the mounting table 190.

Further, an element that handles the liquid, such as the dialysate circuit 52, is attached to the inner vertical plate 32. Elements such as the first dialysate supply circuit 101 and the second waste liquid circuit 104 are arranged in the internal space S1, and the second dialysate supply circuit 102, the first waste liquid circuit 103 and the like are arranged in the internal space S2. Elements are arranged.

Some of the elements of the element group 14 are attached to the front door 12. For example, the blood pump 80 is provided on the front door 12. The blood purifier 50 is held by an arm (not shown) provided in the housing 10.

According to the present embodiment, the housing 10 has two outer vertical plates 30 and 31 facing each other and an inner vertical plate 32 connecting the two outer vertical plates 30 and 31, and the element group 14 Since the element of is attached to the inner vertical plate 32 and the outer vertical plates 30 and 31, it is easy for the user to access when performing maintenance of the element. In addition, it is easy to check the arrangement of each element and the connection status between elements such as tubes. Further, since the three vertical plates 30, 31, and 32 are connected in an H shape, the strength of the housing 10 is high. Therefore, it is possible to realize a housing 10 having good maintainability while ensuring strength.

Since the housing 10 has a side door 11 that can open and close the internal spaces S1 and S2, the internal spaces S1 and S2 can be accessed by opening the side door 11. Therefore, it is easy to access the internal spaces S1 and S2 at the time of maintenance, and the maintainability can be further improved.

Since the side door 11 is rotatably configured around the vertical axis 11a provided on the back side of the housing 10, the side door 11 is opened from the front side of the blood purification device 1 to access the internal spaces S1 and S2. can. Therefore, the user can suitably perform maintenance even in a narrow space without wrapping around to the back side of the blood purification device 1.

Since the side door 11 extends to the side surface of the control unit 15 and can be opened and closed with respect to the side surface of the control unit 15, maintenance of the control unit 15 can also be performed by opening the side door 11.

Since the first outer vertical plate 30 is arranged on the front surface of the housing 10 and the second outer vertical plate 31 is arranged on the back surface of the housing 10, the internal spaces S1 and S2 of the housing 10 are on both the left and right sides. It is formed on the surface and is easy to maintain.

Since the mounting table 190 on which the storage containers 170 and 171 can be placed is provided on the outer surface of the second outer vertical plate 31, it is not necessary to place the storage containers 170 and 171 around the device and it does not get in the way. Further, the storage containers 170 and 171 can be moved together with the housing 10. The liquid storage container placed on the mounting table 190 may be another liquid storage container, for example, storage containers 121, 122, or the like.

Since the filters 134 and 135 of the hollow fiber membrane module are attached to the outer surface of the second outer vertical plate 31, it is easy to replace the hollow fiber membrane module. The hollow fiber membrane module attached to the outer surface of the second outer vertical plate 31 may be a hollow fiber membrane module for other purposes.

Although the preferred embodiments of the present invention have been described above with reference to the accompanying drawings, the present invention is not limited to such examples. It is clear that a person skilled in the art can come up with various modifications or modifications within the scope of the ideas described in the claims, and these also naturally belong to the technical scope of the present invention. It is understood that it is a thing.

For example, the overall configuration of the blood purification device 1 in the above embodiment is not limited to this, and may have other configurations. The configuration (arrangement, type, number, etc.) of the element group 14 of the blood purification device 1 is not limited to that of the above embodiment. The mounting position of each element of the element group 14 on the housing 10 is not limited to that of the above embodiment. For example, some or all of the elements of the element group 14 may be attached to either the outer vertical plate or the inner vertical plate. The blood purification device 1 of the above embodiment is for performing dialysis treatment, but it can also be used for other blood purification treatments such as plasma exchange therapy, leukocyte removal therapy, continuous slow hemofiltration therapy and the like. The present invention is applicable.

INDUSTRIAL APPLICABILITY The present invention is useful in realizing a blood purification device having a housing having a housing that is easy to maintain while ensuring strength.

1 Blood purification device 10 Housing 11 Side door 14 Element group 30 First outer vertical plate 31 Second outer vertical plate 32 Inner vertical plate 50 Blood purifier

Claims (6)

With the housing
With multiple elements for performing blood purification treatment,
The housing has two outer vertical plates facing each other and an inner vertical plate arranged between the two outer vertical plates and connecting the two outer vertical plates to each other.
The two outer vertical plates and the inner vertical plate are substantially H-shaped when viewed from above.
At least one of the plurality of elements is attached to at least one of the inner vertical plate or the outer vertical plate.
An internal space surrounded by the inner vertical plate and the outer vertical plate is formed on both sides of the inner vertical plate.
The housing has a door that can open and close each of the internal spaces.
The plurality of elements include a metering chamber for supplying and draining liquid to the blood purifier.
The metering chamber is a blood purification device attached to the inner vertical plate . The blood purification device according to claim 1, wherein the door is rotatably configured around a vertical axis provided on the back surface side of the housing. A control unit is provided on the housing.
The blood purification device according to claim 1 or 2, wherein the door extends to the side surface of the control unit. The first outer vertical plate of the two outer vertical plates is arranged on the front surface of the housing, and the second outer vertical plate is arranged on the back surface of the housing, according to any one of claims 1 to 3. The described blood purification device. The plurality of elements include a liquid storage container for storing the liquid used in the blood purification process.
The blood purification apparatus according to claim 4, wherein a mounting portion on which the liquid storage container can be placed is provided on the outer surface of the second outer vertical plate. The plurality of elements include a hollow fiber membrane module.
The blood purification device according to claim 4 or 5, wherein the hollow fiber membrane module is attached to the outer surface of the second outer vertical plate.

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