JP7095260B2 - Mixed injection device - Google Patents

Description

The present invention relates to a mixed injection device that executes a mixed injection process of injecting a drug such as an anticancer drug contained in a drug container into an infusion container.

A mixed injection device is known that sucks a drug such as an anticancer drug contained in a drug container such as an ampoule or a vial with a syringe and injects the drug into an infusion bag containing the infusion solution. (See, for example, Patent Document 1). More specifically, a tray containing one or more drug containers that satisfy the amount of drug to be dispensed shown in the preparation data is loaded into the mixed injection device, and the mixed injection is performed using the drug container placed on the tray. The process is executed.

Japanese Unexamined Patent Publication No. 2012-25016

By the way, in the configuration in which only the chemicals in the chemical container placed on the tray corresponding to the preparation data are used in the mixed injection processing corresponding to the preparation data, the chemicals in the chemical container loaded in the mixed injection device are effectively used. It may not be done. For example, if the chemical container used in the mixed injection process based on the preparation data is loaded into the mixed injection device and then the mixed injection process is canceled, or if the chemical remains in the chemical container after the mixed injection process, the mixed injection device is used. The chemicals in the chemical container loaded inside are not used effectively.

An object of the present invention is to provide a mixed injection device capable of supporting the efficient use of a chemical in a chemical container loaded in the mixed injection device.

The mixed injection apparatus according to the present invention includes a mixed injection processing unit capable of performing a mixed injection process of injecting a drug in a first container into a second container based on preparation data, and a mixed injection control unit that controls the mixed injection processing unit. Be prepared. Then, in the mixed injection process based on the first preparation data by the mixed injection processing unit, the mixed injection control unit is loaded into the mixed injection device in advance in association with the second preparation data different from the first preparation data. 1 The chemicals in the container can be used.

Further, the mixed injection device stores at least a tray accommodating portion capable of accommodating a plurality of trays on which the first container is placed, and a first storage that stores first correspondence information indicating a correspondence relationship between the preparation data and the tray. The mixed injection control unit includes a processing unit, and in the mixed injection processing based on the first preparation data by the mixed injection processing unit, the said first correspondence information among the trays accommodated in the tray accommodating unit. It is considered that the chemicals in the first container contained in the tray associated with the second preparation data can be used.

Further, the mixed injection device is provided in the mixed injection processing unit, and the container mounting unit on which one or a plurality of the first containers can be placed, and the preparation data and the container mounting unit are mounted. The mixed injection control unit includes a second storage processing unit that stores a second correspondence information indicating a correspondence relationship with the first container, and the mixed injection control unit performs the mixed injection processing based on the first preparation data by the mixed injection processing unit. Of the first container placed on the container mounting portion, the chemical in the first container stored in the tray associated with the second preparation data in the second correspondence information can be used. It is conceivable that.

Further, the mixed injection control unit can execute a pre-stirring process in which the stirring step of stirring the chemicals in the first container in the mixed injection process by the mixed injection processing unit is executed before the execution start timing of the mixed injection process. Therefore, it is considered that the first container after the pre-stirring treatment can be placed on the container mounting portion.

Further, when the mixed injection device includes a syringe mounting unit on which one or a plurality of syringes can be placed and the mixed injection control unit retains chemicals in the first container after the mixed injection process is executed, the first container is used. After sucking the medicine remaining in one container with a syringe, the syringe can be placed on the syringe mounting portion, and is housed in the syringe placed on the syringe mounting portion in the mixed injection process. It is possible that chemicals can be used.

Further, when the mixed injection device includes a syringe dispensing unit capable of taking out a syringe from the mixed injection processing unit, and the mixed injection control unit has a chemical remaining in the first container after the mixed injection processing is executed, the first container is used. After sucking the medicine remaining in the container with a syringe, it is considered that the syringe can be moved to the syringe discharge unit.

Further, the mixed injection device according to the present invention includes a mixed injection processing unit capable of performing a mixed injection process of injecting a chemical in a first container into a second container based on preparation data, and a mixed injection control unit for controlling the mixed injection processing unit. A storage unit that can store a plurality of container shape information regarding the shape of the first container for each drug is provided. Then, the mixed injection processing unit includes a robot arm capable of holding the first container based on the container shape information, and the mixed injection control unit is selected from the plurality of container shape information according to a user operation. The robot arm can be controlled based on the container shape information.

According to the present invention, a mixed injection device capable of supporting the efficient use of chemicals in a chemical container loaded in the mixed injection device is realized.

FIG. 1 is a block diagram showing a system configuration of a mixed injection device according to an embodiment of the present invention. FIG. 2 is a perspective view showing an external configuration of a mixed injection device according to an embodiment of the present invention. FIG. 3 is a perspective view showing a state in which a part of the accommodating unit of the mixed injection device according to the embodiment of the present invention is omitted. FIG. 4 is a front view showing a state in which a part of the main door and the front wall of the mixed injection device according to the embodiment of the present invention is removed. FIG. 5 is a perspective view showing a tray used in the mixed injection device according to the embodiment of the present invention. FIG. 6 is a perspective view of the mixed injection device according to the embodiment of the present invention as viewed from below. FIG. 7 is a perspective view showing a holding portion of the first robot arm of the mixed injection device according to the embodiment of the present invention. FIG. 8 is a perspective view showing a holding portion of the second robot arm of the mixed injection device according to the embodiment of the present invention. FIG. 9 is a schematic plan view showing a tray transport portion of the mixed injection device according to the embodiment of the present invention. FIG. 10 is a perspective view showing the mechanism of the tray transport portion of the mixed injection device according to the embodiment of the present invention. FIG. 11 is a perspective view showing an ampoule cutter of the mixed injection device according to the embodiment of the present invention. FIG. 12 is a perspective view showing the internal configuration of the stirring device of the mixed injection device according to the embodiment of the present invention. FIG. 13 is a perspective view showing a chemical reading unit of the mixed injection device according to the embodiment of the present invention. FIG. 14 is a perspective view showing a needle bending detection unit of the mixed injection device according to the embodiment of the present invention. FIG. 15 is a perspective view showing the internal structure of the injection needle attachment / detachment device of the mixed injection device according to the embodiment of the present invention. FIG. 16 is a perspective view showing the internal structure of the injection needle attachment / detachment device of the mixed injection device according to the embodiment of the present invention. FIG. 17 is a diagram showing an example of an image taken by a needle insertion confirmation camera of the mixed injection device according to the embodiment of the present invention. FIG. 18 is a diagram showing a configuration of a housing unit of the mixed injection device according to the embodiment of the present invention. FIG. 19 is a diagram showing a configuration of a housing unit of the mixed injection device according to the embodiment of the present invention. FIG. 20 is a diagram showing a configuration of a housing unit of the mixed injection device according to the embodiment of the present invention. FIG. 21 is a diagram showing a configuration of a housing unit of the mixed injection device according to the embodiment of the present invention. FIG. 22 is a flowchart showing an example of the procedure of the mixed injection management process executed by the mixed injection device according to the embodiment of the present invention. FIG. 23 is a diagram showing an example of a display screen in the loading preparation process executed by the mixed injection device according to the embodiment of the present invention. FIG. 24 is a flowchart showing an example of a procedure of mixed injection control processing executed by the mixed injection device according to the embodiment of the present invention. FIG. 25 is a diagram showing an example of correspondence information used in the mixed injection device according to the embodiment of the present invention. FIG. 26 is a flowchart showing an example of a procedure of mixed injection start processing executed by the mixed injection apparatus according to the embodiment of the present invention. FIG. 27 is a flowchart showing an example of a procedure of mixed injection control processing executed by the mixed injection device according to the embodiment of the present invention. FIG. 28 is a diagram for explaining an operation example of the mixed injection device according to the embodiment of the present invention. FIG. 29 is a diagram for explaining an operation example of the mixed injection device according to the embodiment of the present invention. FIG. 30 is a flowchart showing an example of a procedure of batch adjustment inspection processing executed by the mixed injection device according to the embodiment of the present invention. FIG. 31 is a flowchart showing an example of a procedure of batch stirring inspection processing executed by the mixed injection device according to the embodiment of the present invention. FIG. 32 is a flowchart showing an example of a procedure of batch total collection inspection processing executed by the mixed injection device according to the embodiment of the present invention. FIG. 33 is a flowchart showing an example of a procedure of shape selection processing executed by the mixed injection device according to the embodiment of the present invention. FIG. 34 is a diagram for explaining an error correction function of the mixed injection device according to the embodiment of the present invention. FIG. 35 is a plan view of a rubber stopper of an infusion bag used in the mixed injection device according to the embodiment of the present invention. FIG. 36 is a diagram for explaining an example of a suction step in the mixed injection device according to the embodiment of the present invention. FIG. 37 is a diagram for explaining a display example in the mixed injection device according to the embodiment of the present invention. FIG. 38 is a diagram for explaining an operation example of the mixed injection device according to the embodiment of the present invention.

Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings for the purpose of understanding the present invention. It should be noted that the following embodiment is an example embodying the present invention and does not limit the technical scope of the present invention.

[First Embodiment]
First, the first embodiment will be described. For each of the embodiments described below, the same reference numerals may be given to the same configurations or processes, and the description thereof may be omitted.

[Mixed injection device 1]
As shown in FIGS. 1 and 2, the mixed injection device 1 according to the present embodiment includes a mixed injection control unit 100, a chemical loading unit 200, a mixed injection processing unit 300, an accommodation unit 700, and a stirring device 32. The mixed injection device 1 is installed in a medical facility such as a hospital. Then, in the mixed injection device 1, the operation of the mixed injection processing unit 300 and the accommodation unit 700 is controlled by the mixed injection control unit 100 based on the preparation data, so that the anticancer drug shown in the preparation data is shown by the syringe. A mixed injection process is performed in which a drug such as an agent is injected from a first container such as an ampoule or vial containing a predetermined amount of the drug into a second container such as an infusion bag. The mixed injection process also includes a process of sucking a drug from a first container such as an ampoule or a vial with a syringe and injecting the drug into a second container such as another ampoule or a vial.

[Mixed injection control unit 100]
First, a schematic configuration of the mixed injection control unit 100 will be described with reference to FIG. 1. The mixed injection control unit 100 includes a first control unit 400 and a second control unit 500 that are communicably connected. The first control unit 400 is provided on the chemical loading unit 200 side, and the second control unit 500 is provided on the mixed injection processing unit 300 side.

The processing sharing of each of the first control unit 400 and the second control unit 500 described in the present embodiment is only an example, and each processing procedure such as the mixed injection processing is described in the first control unit 400 and the second control unit 400. It may be executed by any of the control units 500. Further, it is considered as another embodiment that the mixed injection control unit 100 has only one control unit or three or more control units. Further, a part or all of the processes executed by the first control unit 400 and the second control unit 500 may be executed by an electronic circuit such as an ASIC or a DSP.

Further, the first control unit 400 can communicate with a higher-level system 600 such as an electronic medical record system or a dispensing management system that inputs preparation data to the mixed injection device 1. The preparation data is preparation data generated based on the prescription data or the prescription data itself. The prescription data includes, for example, prescription delivery date, patient ID, patient name, patient birth date, drug information (drug code, drug name, dose, etc.), dosage form information (internal use, external use, etc.), usage information ( Includes medical care type (outpatient, inpatient, etc.), prescription department, ward, and hospital room (such as after each meal three times a day). In addition, the preparation data includes, for example, preparation ID, patient information (patient ID, patient name, etc.), doctor information, drug information, prescription amount of drug, type of drug container (ampoule containing drug solution, vial bottle containing drug solution, or powdered drug). Information on preparation details (drug container, syringe, type and number of injection needles used for mixed injection processing, etc.), preparation procedure information (work details, dissolving agent, solvent, amount of dissolving agent, amount of solvent, amount of sampling) ), Preparation date, prescription classification, medication date, medical department, ward, preparation end designated time (or scheduled start time), required time, etc. are included.

The first control unit 400 is a personal computer including a CPU 401, a ROM 402, a RAM 403, a data storage unit 404, an operation unit 405, and the like. Further, various electric parts such as a display 203, a bar code reader 204, and an air purifying device 205, which will be described later, provided in the chemical loading unit 200 are connected to the first control unit 400.

The CPU 401 is a processor that executes processing according to various control programs. The ROM 402 is a non-volatile memory in which a program such as a BIOS executed by the CPU 401 is stored in advance. The RAM 403 is a volatile memory or a non-volatile memory used for deploying various control programs by the CPU 401 and temporarily storing data.

The data storage unit 404 is a non-volatile storage device such as a hard disk that stores various application programs and various data for causing the CPU 401 to execute various processes. For example, the data storage unit 404 stores the preparation data input from the host system 600.

The first control unit 400 stores the identification information of the tray 101, which will be described later, corresponding to the preparation data together with the preparation data input from the higher-level system 600 in the data storage unit 404. For example, the association between the preparation data and the identification information of the tray 101 is performed by the first control unit 400. It is also conceivable that information indicating the correspondence between the preparation data and the identification information of the tray 101 is input from the higher-level system 600 to the mixed injection device 1 together with the preparation data.

Further, the data storage unit 404 stores various databases such as an injection needle master, a drug master, a patient master, a doctor master, a prescription classification master, a clinical department master, and a ward master. The shape of the needle tip of the injection needle is stored in the injection needle master for each type of injection needle. The shape of the needle tip portion of the injection needle includes the outer diameter of the needle tube of the injection needle, the angle of the tip, the length of the cut surface (inclined surface), and the like. In addition, the drug master includes drug code, drug name, JAN code (or RSS), drug bottle code, classification (dosage form: powder (powder), tablet, liquid medicine, external medicine, etc.), specific gravity, drug type ( Ordinary drugs, anti-cancer drugs, poisonous drugs, drugs, powerful drugs, anti-psychiatric drugs, therapeutic drugs, etc.), formulation changes, shaping drugs, precautions, types of drug containers (ampoules, vials), drugs in drug container units Information such as the capacity (predetermined amount), the shape information of the medicine container, and the weight of the medicine container is included. The container shape information of the chemical container includes the outer diameter of the chemical container, the thickness of the rubber stopper of the chemical container, the puncture position, the depth of the chemical container, the external image of the chemical container, and the rubber stopper of the chemical container. Various information such as a plane image and a registration date of container shape information is included. In the pharmaceutical master, as information on the infusion bag 12 in which an infusion solution such as sanitary saline solution or glucose is stored, for example, the container type (soft bag, hard type, AL type) of the infusion bag 12 and the infusion bag Information such as the amount of infusion solution contained in 12 and the amount of liquid that can be injected into the infusion bag 12 is also included.

Further, the data storage unit 404 stores in advance a first mixed injection control program for causing the CPU 401 to execute various processes. The first mixed injection control program is read from a recording medium such as a CD, DVD, BD, or flash memory by a reading device (not shown) included in the first control unit 400, and is installed in the data storage unit 404. You may.

The operation unit 405 includes various operation units such as a keyboard, a mouse, or a touch panel that accept various user operations in the first control unit 400.

The second control unit 500 is a personal computer including a CPU 501, a ROM 502, a RAM 503, a data storage unit 504, an operation unit 505, and the like. The second control unit 500 includes a first robot arm 21, a second robot arm 22, a tray transport unit 110, a touch panel monitor 14, an IC reader 101c, an IC reader 15a, and a tray, which will be described later, provided in the mixed injection processing unit 300. Various electrical parts such as the confirmation camera 41 and the injector confirmation camera 42 are connected.

The CPU 501 is a processor that executes processing according to various control programs. The ROM 502 is a non-volatile memory in which a program such as a BIOS executed by the CPU 501 is stored in advance. The RAM 503 is a volatile memory or a non-volatile memory used for deploying various control programs by the CPU 501 and temporarily storing data.

The data storage unit 504 is a hard disk or the like that stores various application programs and various data for causing the CPU 501 to execute various processes. Specifically, the data storage unit 504 stores in advance a second mixed injection control program for causing the CPU 501 to execute a mixed injection process described later. The second mixed injection control program is read from a recording medium such as a CD, DVD, BD, or flash memory by a reading device (not shown) included in the second control unit 500, and is installed in the data storage unit 504. You may. Further, the data storage unit 504 also stores the drug master similar to the data storage unit 404, and the second control unit 500 can refer to the drug master. As another embodiment, the second control unit 500 may be configured to be able to acquire the information of the drug master via the first control unit 400.

In the present invention, the first mixed injection control program, the second mixed injection control program, or the first mixed injection control program and the first mixed injection control program for causing the CPU 401 and the CPU 501 to execute various processes in the mixed injection control unit 100. 2 It may be regarded as an invention of a mixed injection control program in which a mixed injection control program is integrated. Further, the present invention is a computer-readable recording medium recording a mixed injection control program in which the first mixed injection control program, the second mixed injection control program, or the first mixed injection control program and the second mixed injection control program are integrated. It may be regarded as an invention. Further, the present invention may be regarded as an invention of a mixed injection method including one or a plurality of processing procedures executed in the mixed injection device 1.

The operation unit 505 includes various operation units such as a keyboard, a mouse, or a touch panel that accept various user operations in the second control unit 500.

[Chemical loading unit 200]
Next, the schematic configuration of the chemical loading unit 200 will be described with reference to FIGS. 2 and 3. Note that FIG. 3 is a diagram showing a main part of the internal configuration of the chemical loading unit 200, and the description of the accommodating unit 700 is omitted.

As shown in FIGS. 2 and 3, the chemical loading unit 200 is a clean bench including a door 201, a work table 202, a display 203, a bar code reader 204, and an air purifying device 205. The chemical loading unit 200 and the mixed injection processing unit 300 are communicated with each other by a tray loading port 114 (see FIG. 6) and a tray discharging port 701 (see FIG. 21) formed on the side surface of the mixed injection processing unit 300. There is.

The work table 202 is used to perform preparatory work for the mixed injection process executed by the mixed injection device 1, and the barcode reader 204, the tray 101, and the like are placed on the work table 202. Further, on the front surface of the work table 202, a tray discharge port 206 that is opened and closed when the tray 101 discharged from the storage unit 700 is taken out is provided. Further, in the work table 202, an IC reader 207 (see FIG. 21) capable of reading information from the IC tag 101b of the tray 101 placed on the work table 202 is provided. The reading result by the IC reader 207 is input to the first control unit 400.

The display 203 is a display unit such as a liquid crystal display or an organic EL display that displays various information in response to a control instruction from the first control unit 400. Specifically, the display 203 displays preparation data and the like that are candidates for the mixed injection target in the mixed injection device 1. Further, the barcode reader 204 reads a barcode written on a prescription, a preparation instruction sheet, or the like, and inputs the content of the barcode to the first control unit 400. The air purifier 205 supplies air into the chemical loading unit 200 through a predetermined filter. The display 203 may be supported by, for example, the front panel 700A (see FIGS. 18 to 21) included in the accommodation unit 700.

The door 201 is provided on the front surface of the chemical loading section 200 and is a transparent member that can be opened and closed vertically in the vertical direction. As shown in FIG. 2, the user performs the preparatory work of the mixed injection process executed by the mixed injection device 1 in a state where the door 201 is slightly opened and the hand is put in the chemical loading unit 200. Specifically, as shown in FIG. 5, the tray 101 placed on the work table 202 has a chemical container 10 (an example of a first container) used in the mixed injection process executed by the mixed injection device 1. , A syringe 11, an infusion bag 12 (an example of a second container), and the like are accommodated. The infusion bag 12 contains an infusion solution such as a predetermined amount of physiological saline, glucose, or a high-calorie infusion solution corresponding to the type of the infusion bag 12. The drug contained in the drug container 10 is, for example, an anticancer drug, but may be a drug other than the anticancer drug. The preparatory work includes, for example, a loading operation in which the medicine container 10, the syringe 11, and the infusion bag 12 are placed in a predetermined position on the tray 101, and the tray 101 is loaded into the storage unit 700. .. Hereinafter, when the chemical container 10 is an ampoule, the chemical container 10 may be referred to as an ampoule 10A, and when the chemical container 10 is a vial bottle, the chemical container 10 may be referred to as a vial bottle 10B. be.

As shown in FIG. 5, the tray 101 includes an electronic paper 101a on which a patient name and application are displayed in characters, and an IC tag 101b (recording medium) such as an RFID (Radio Frequency Identification) tag on which various information can be read and written. An example) and. The IC tag 101b is provided on the bottom surface of the tray 101, and the IC tag 101b stores identification information for identifying the tray 101.

Further, the tray 101 holds the equipment mounting portion 102 (see FIG. 9) on which the medicine container 10 and the syringe 11 (syringe 11a, injection needle 11c, cap 11d) are placed, and the infusion bag 12. It has an infusion bag holding portion 103 (see FIG. 5). The equipment mounting portion 102 and the infusion bag holding portion 103 can be individually attached to and detached from the tray 101.

As shown in FIG. 5, the equipment mounting portion 102 is provided with a support portion 102A that supports the ampoule 10A in an inclined state. Then, the ampoule 10A is set in a state of being erected diagonally by the support portion 102A. As a result, chemicals do not collect on the neck of the ampoule 10A. Further, in addition to the ampoule 10A, an injection needle 11c or the like to which the cap 11d is attached is also set in a state of being obliquely erected on the support portion 102A.

The injection needle 11c also includes an injection needle with a syringe filter. Specifically, when the ampoule 10A is used, the debris when the neck of the ampoule 10A is broken is injected from the syringe 11 into the infusion bag 12, or the debris flows into the syringe 11. An injection needle with a syringe filter is used to prevent this. The syringe filter is a filter generally also referred to as a coma-type filter, and has a function of preventing the passage of foreign substances other than chemicals. For example, a syringe filter manufactured by Nippon Pole Co., Ltd. is generally known.

On the other hand, the vial bottle 10B and the syringe 11 are set in a state of being laid down on the equipment mounting portion 102 as shown in FIGS. 5 and 9. At this time, the syringe 11 is in a state where the syringe 11a and the injection needle 11c are separated. Of course, the arrangement form in the equipment mounting portion 102 described here is an example, and the present invention is not limited to this.

As shown in FIG. 5, the infusion bag holding portion 103 is provided with a chuck portion 140 for fixing the mixed injection port (neck portion) of the infusion bag 12. In the preparatory work, the user sets the infusion bag 12 in the infusion bag holding portion 103 in a state of being held by the chuck portion 140. Further, the infusion bag holding portion 103 is provided with an engaging hole portion 103a used for raising and lowering the infusion bag holding portion 103.

Then, the tray 101 is housed in the storage unit 700 after the medicine container 10, the syringe 11, and the infusion bag 12 are set by the user. As will be described later, the storage unit 700 can accommodate a plurality of the trays 101. As a result, as will be described later, the tray 101 is automatically supplied from the accommodating unit 700 to the mixed injection processing unit 300 through the tray discharge port 701 and the tray loading port 114 as needed. After that, after the mixed injection processing in the mixed injection processing unit 300 is completed, the tray 101 is discharged from the tray discharge port 15 (see FIG. 3) of the mixed injection processing unit 300 in a state where the infusion bag 12 is housed. Alternatively, it is discharged from the tray discharge port 206 (see FIG. 3) of the chemical loading unit 200 via the storage unit 700. The mixed injection processing unit 300 may be provided with a carry-in port capable of directly supplying the tray 101 from the chemical loading unit 200 to the mixed injection processing unit 300.

[Mixed injection processing unit 300]
Subsequently, the schematic configuration of the mixed injection processing unit 300 will be described.

As shown in FIGS. 2 to 4, a main door 301, a syringe take-out door 302, a dust storage room door 13, a touch panel monitor 14, a tray discharge port 15, and the like are provided on the front surface of the mixed injection processing unit 300. ..

The main door 301 is opened and closed to access the inside of the mixed injection processing chamber 104, for example, when cleaning the inside of the mixed injection processing chamber 104 provided in the mixed injection processing unit 300. Further, in the mixed injection device 1, in addition to paying out the infusion bag 12 into which the medicine is injected, it is also possible to pay out the syringe 11 in a state where the medicine is filled. The syringe take-out door 302 is opened and closed when the syringe 11 is taken out from the mixed injection processing chamber 104.

The garbage storage chamber door 13 is for removing the waste from the garbage storage chamber 13a in which the waste such as the chemical container 10 and the syringe 11 after being used in the mixed injection treatment in the mixed injection processing chamber 104 is stored. It is opened and closed. Further, the tray discharge port 15 is opened and closed to take out the tray 101 on which the infusion bag 12 is placed after the chemicals have been mixed-injected by the mixed-injection process in the mixed-injection processing chamber 104.

The touch panel monitor 14 is a display unit such as a liquid crystal display or an organic EL display that displays various information in response to a control instruction from the second control unit 500. Further, the touch panel monitor 14 has a touch panel that accepts touch operations by the user. The touch panel monitor 14 can display, for example, an image or a video image taken by various cameras described later.

Further, as shown in FIG. 4, in the garbage storage chamber 13a, a waste container 13b for disposing of a liquid such as an infusion solution contained in the infusion bag 12 and a weighing scale for measuring the weight of the waste container. 13c is provided. The waste container 13b can be attached to and detached from the garbage storage chamber 13a with the garbage storage chamber door 13 open. Further, on the bottom surface of the mixed injection processing chamber 104, a communication port (not shown) communicating with the waste container 13b is formed above the waste container 13b. The second robot arm 22, which will be described later, can operate the syringe 11 to dispose of the liquid in the syringe 11 into the waste container 13b from the communication port. The weighing meter 13c has, for example, a load cell for inputting an electric signal corresponding to the weight of the waste container 13b to the second control unit 500.

As a result, the second control unit 500 acquires the amount of the liquid to be discarded at the time of disposal of the liquid, based on the result of weighing the waste container 13b by the weighing meter 13c before and after the disposal of the liquid into the waste container 13b. It is possible. For example, the second control unit 500 collates the amount of liquid discarded from the syringe 11 with the amount of waste determined based on the preparation data and the like, and if the collation results do not match, the touch panel monitor 14 makes an error. Etc. to notify the user. Further, the second control unit 500 records the collation result in the data storage unit 504 as history information of the mixed injection process. This makes it possible to accurately check the consistency of the amount of waste from the syringe 11 and manage the amount of waste liquid.

As a case where the liquid is discarded using the syringe 11, for example, in the mixed injection process, the amount of liquid in the infusion bag 12 exceeds the maximum permissible amount set in advance corresponding to the infusion bag 12. In addition, it is conceivable that the infusion solution may be removed from the infusion solution bag 12 in advance and discarded. Further, in such a case, the second control unit 500 weighs the amount of liquid extracted from the infusion bag 12 by the syringe 11 using a weigher 35 or the like provided in the mixed injection processing chamber 104. It may be collated with the preparation data. Further, the second control unit 500 may collate the weighing result by the weighing meter 35 with the weighing result by the weighing meter 13c.

[Mixed injection processing room 104]
As shown in FIGS. 3 and 4, the mixed injection processing chamber 104 includes a first robot arm 21, a second robot arm 22, an ampoule cutter 31, the stirring device 32, a mounting shelf 33, a chemical reading unit 34, and a weighing unit. A total of 35, a needle bending detection unit 36, a mixed injection communication port 37, a needle insertion confirmation transparent window 38, a dust lid 132a, and the like are provided. Further, as shown in FIG. 6, a tray confirmation camera 41, a syringe confirmation camera 42, an injection needle attachment / detachment device 43, a needle insertion confirmation camera 44, a germicidal lamp 45, and the like are provided on the ceiling side of the mixed injection processing chamber 104. There is.

[1st robot arm 21, 2nd robot arm 22]
The first robot arm 21 and the second robot arm 22 are drive units having an articulated structure, and are provided in a hanging shape with a base end portion fixed to the ceiling side of the mixed injection processing chamber 104. For example, the joints of the first robot arm 21 and the second robot arm 22 have 5 to 8 axes, respectively. Then, in the mixed injection device 1, each work step in the mixed injection process is executed by the dual-arm type first robot arm 21 and the second robot arm 22.

Specifically, the second control unit 500 individually drives the drive motors provided at the joints of the first robot arm 21 and the second robot arm 22, and the first robot arm 21 and the second robot arm 21. The robot arm 22 is made to execute each work in the mixed injection process. The mixed injection processing unit 300 has, for example, a configuration having one robot arm, a configuration including three or more robot arms, or a configuration without a robot arm, as long as the structure can execute the mixed injection processing. May be.

As shown in FIG. 6, the first robot arm 21 includes a holding portion 25 capable of holding equipment such as the medicine container 10 and the syringe 11, and the holding portion 25 has a predetermined movable range. It is possible to move it to any position within. The second robot arm 22 can hold equipment such as the medicine container 10 and the syringe 11 and move it to an arbitrary position, and also performs an operation of sucking and injecting the medicine by the syringe 11. It is provided with a holding portion 26 capable of performing. Further, the second robot arm 22 can move the medicine container 10, the syringe 11, and the like to any position within a predetermined movable range.

As shown in FIG. 7, the holding portion 25 of the first robot arm 21 includes a pair of gripping claws 25a, a motor 251 and two screw shafts 252 and 253 rotated by the motor 251 and the screw. It includes nut blocks 254 and 255 screwed onto shafts 252 and 253. The pair of gripping claws 25a are fixed to the nut blocks 254 and 255, respectively. Then, the nut blocks 254 and 255 move due to the rotation of the screw shafts 252 and 253, and the pair of gripping claws 25a hold and release the holding portion 25 in close proximity to and away from each other.

Further, the pair of gripping claws 25a is a gripping portion having a recess suitable for holding the vial bottle 10B and having a recess suitable for holding the ampoule 10A on the tip side. FIG. 7 shows that both the ampoule 10A and the vial bottle 10B are held, but in reality, one ampoule 10A or the vial bottle 10B is held.

Further, the holding portion 25 can also hold the injection needle 11c or the syringe 11 to which the cap 11d is attached by the pair of gripping claws 25a. By the way, the second control unit 500 may measure the diameter of the syringe 11 according to the driving amount of the motor 251 when the syringe 11 is held by the pair of gripping claws 25a of the holding unit 25. It is possible. Therefore, the second control unit 500 can determine whether or not the syringe 11 is the syringe specified in the preparation content information of the preparation data.

As shown in FIG. 8, the holding portion 26 of the second robot arm 22 includes a syringe holding portion 261, a plunger holding portion 262, and a moving portion 263. The syringe holder 261 includes a pair of gripping claws 261a that hold the syringe 11a of the syringe 11. The pair of gripping claws 261a are gripping portions that hold and release the syringe 11a of the syringe 11 in close proximity to and separated from each other by a mechanism similar to the driving mechanism used in the holding portion 25. Further, in the pair of gripping claws 261a, inclined portions 261b that incline downward from the upper end surface of the gripping claws 261a toward the facing surfaces are formed on facing surfaces facing each other.

The plunger holding portion 262 includes a pair of gripping claws 262a for holding the flange portion of the plunger 11b of the syringe 11. The pair of gripping claws 262a are gripping portions that hold and release the flange portion of the plunger 11b of the syringe 11 in close proximity to and separated from each other by a mechanism similar to the driving mechanism used in the holding portion 25. be. A gripping claw 262b is fixed to the upper surface of each of the gripping claws 262a. Each of the gripping claws 262b is a gripping portion that brings the pair of gripping claws 262a close to each other and separated from each other to grip not only the syringe 11 but also other equipment such as the medicine container 10. A recess for the flange portion of the plunger 11b to enter is formed on the upper surface of the pair of gripping claws 262a on the opposite side. Further, the tips of the pair of gripping claws 262b project forward from the pair of gripping claws 262a, so that the pair of gripping claws 262b can easily grip the ampoule 10A and the vial bottle 10B. The gripping claw 262b may be provided on the gripping claw 261a.

The moving portion 263 can move the plunger holding portion 262 in the moving direction of the plunger 11b of the syringe 11. The moving portion 263 moves the plunger 11b by a drive mechanism such as a motor, a screw shaft rotated by the motor, a nut block screwed to the screw shaft, and a guide. The plunger holding portion 262 is fixed to the nut block and moves by moving the nut block.

When the second control unit 500 controls the holding unit 25 of the first robot arm 21 or the holding unit 26 of the second robot arm 22 to hold the drug container 10, the second control unit 500 can be used as the drug master. Based on the stored container shape information of the drug container 10, the distance between the pair of gripping claws 25a of the holding portion 25 and the like is controlled.

[Tray transport unit 110]
Further, the mixed injection processing unit 300 is provided with a tray transport unit 110 capable of reciprocating the tray 101 between the tray loading port 114 at the right end portion and the tray transport end portion 110a at the left end portion in FIG. Has been done.

Here, FIG. 9 is a schematic plan view showing an example of a transport path of the tray 101 in the tray transport unit 110. The pressure inside the tray transport unit 110 is set to be higher than that in the mixed injection processing chamber 104. As shown in FIG. 9, the tray transport unit 110 passes the tray 101 through the rear side of the dust storage chamber 13a located below the mixed injection processing chamber 104 and under the dust lid 132a. It is provided to carry. As a result, the dust storage chamber 13a can be accessed from the front side of the mixed injection device 1. In FIG. 9, in order to show the transport path of the tray transport section 110, the tray 101 moving in the tray transport section 110 is shown by a chain double-dashed line, and a plurality of the trays in the tray transport section 110 at the same time. 101 does not exist. The tray transport unit 110 may be configured to be capable of simultaneously transporting a plurality of the trays 101 between the tray loading port 114 and the tray transport end portion 110a in the tray transport unit 110.

The tray 101 inserted from the tray loading port 114 can be pulled into the inside of the tray transport starting unit 110b of the tray transport unit 110, or the tray 101 can be discharged from the tray loading port 114. The illustrated belt conveyor is provided. Further, an IC reader 101c and an IC reader 15a capable of reading information from the IC tag 101b provided in the infusion bag holding portion 10 of the tray 101 are provided. For example, the IC reader 101c and the IC reader 15a are RFID readers that read information from RFID tags. The IC reader 101c is provided at a tray transfer start portion 110b where the tray 101 is loaded from the tray loading port 114, and the IC reader 15a is such that the tray 101 is discharged from the tray discharge port 15. It is provided at the tray transfer end portion 110a.

Then, when the second control unit 500 determines that the tray 101 has been inserted into the tray transfer start unit 110b from the tray loading port 114 based on a sensor output (not shown), the IC reader 101c determines that the tray 101 has been inserted into the tray transfer start unit 110b. Read information from tag 101b. Further, when the second control unit 500 determines that the tray 101 has been inserted into the tray transport end unit 110a based on a sensor output (not shown), the IC reader 15a reads information from the IC tag 101b. .. Similarly, when the tray 101 is conveyed from the tray transfer start unit 110b toward the accommodating unit 700 via the tray loading port 114, the second control unit 500 is described by the IC reader 101c. Information can be read from the IC tag 101b. Then, the second control unit 500 executes a tray collation process for determining the suitability of the tray 101 or the like according to the reading result by the IC reader 101c and the IC reader 15a.

Further, the second control unit 500 determines that the tray 101 has reached a predetermined position in the tray transport unit 110 through the tray loading port 114, for example, based on the output of a sensor (not shown). , The shutter 111 that communicates and shields the tray transport unit 110 and the mixed injection processing chamber 104 is slid in the horizontal direction. When the shutter 111 is opened, the equipment mounting portion 102 is exposed in the mixed injection processing chamber 104. FIG. 9 shows a state in which the equipment mounting portion 102 is exposed in the mixed injection processing chamber 104.

As shown in FIG. 10, the tray transport section 110 is a tray that raises and lowers the equipment mounting section 102 in the tray 101 that has been moved into the tray transport section 110 through the tray loading port 114. An elevating part 112 is provided. The tray elevating part 112 lifts the equipment mounting part 102 from the bottom to the top by, for example, driving the four shafts 112a provided so as to be able to move up and down in the vertical direction.

Then, the second control unit 500 raises the equipment mounting unit 102 by the tray elevating unit 112, and then takes a picture with the tray confirmation camera 41. The tray confirmation camera 41 photographs the medicine container 10 and the syringe 11 and the like placed on the equipment mounting portion 102, which are predetermined, from above. The second control unit 500 executes an image recognition process using the captured image of the tray confirmation camera 41, and the number of the drug container 10 and the syringe 11 (syringe 11a and the injection needle) shown in the preparation data. It is determined whether or not 11c) or the like is present on the equipment mounting portion 102.

Further, as shown in FIG. 10, the tray transport end portion 110a located in the space on the left side of the mixed injection processing chamber 104 is provided with a bag elevating portion 113 for raising and lowering the infusion bag holding portion 103. After the tray 101 is conveyed to the front of the bag elevating portion 113, the second control unit 500 hooks the hook portion 113a of the bag elevating portion 113 to the engaging hole portion 103a from below. Then, the second control unit 500 raises the infusion bag holding portion 103 by rotationally driving the arc gear portion 113b on which the hook portion 113a is formed by the motor 113c, and opens the mixed injection port of the infusion bag 12. It is located at the mixed injection communication port 37. Further, the second control unit 500 drives the bag elevating unit 113 to incline the infusion bag holding unit 103 by controlling the motor 113c, and causes the mixed injection port of the infusion bag 12 to face upward or downward. can do.

In particular, the second control unit 500 adjusts the tilt angle of the mixed injection port of the infusion bag 12 to a preset tilt angle by controlling the motor 113c to adjust the drive amount of the bag elevating section 113. It is possible to do.

Specifically, in the pharmaceutical master, the upper limit injection amount that can be injected into the infusion bag 12 without bleeding air and the upper limit injection amount that is set when the upper limit injection amount is exceeded, corresponding to each type of the infusion bag 12. The exception tilt angle, which is the tilt angle of the mixed injection port of the infusion bag 12, is stored. Then, in the mixed injection process based on the preparation data, the second control unit 500 uses the syringe 11 in advance when the amount of liquid injected into the infusion bag 12 exceeds the upper limit injection amount. An air bleeding step of bleeding air from the infusion bag 12 is performed. In this case, the amount of air in the infusion bag 12 is reduced. Therefore, when the inclination of the infusion bag 12 becomes large, the liquid in the infusion bag 12 may come into contact with the rubber stopper of the mixed injection port of the infusion bag 12, and the liquid when the injection needle 11c is taken out from the rubber stopper. May leak out.

On the other hand, in the mixed injection device 1, when the amount of liquid injected into the infusion bag 12 is equal to or less than the upper limit injection, the second control unit 500 adjusts the inclination angle of the mixed injection port of the infusion bag 12. Set to a preset specified angle. The specified angle is, for example, a value set as an inclination angle of the mixed injection port common to the plurality of types of the infusion bag 12.

On the other hand, when the amount of liquid injected into the infusion bag 12 in the mixed injection process exceeds the upper limit injection amount, the second control unit 500 sets the inclination angle of the mixed injection port of the infusion bag 12 to the exception inclination angle. do. The exception tilt angle is such that the tilt angle of the mixed injection port of the infusion bag 12 with respect to the vertical direction is at least smaller than the specified angle. That is, the exception inclination angle is an angle at which the infusion bag 12 is closer to vertical than the specified angle. As a result, when the inclination angle of the mixed injection port of the infusion bag 12 is set to the exception inclination angle, the possibility that the liquid in the infusion bag 12 comes into contact with the rubber stopper of the mixed injection port is reduced. The possibility of liquid leaking when the injection needle 11c is pulled out from the rubber stopper is reduced. The exception inclination angle may be used, for example, when the type of the infusion bag 12 is a so-called AL type having a small amount of air inside.

Further, as shown in FIG. 6, above the tray transport end portion 110a, a dome-shaped light 120 for illuminating the infusion bag 12 transported to the tray transport end portion 110a and an infusion camera 121 are provided. There is. The infusion camera 121 is provided in the center of the dome-shaped light 120 and reads a barcode attached to the surface of the infusion bag 12. Thereby, the second control unit 500 can determine the suitability of the infusion bag 12 according to the information of the barcode read by the infusion camera 121.

[Ampoule Cutter 31]
As shown in FIG. 11, the ampoule cutter 31 is provided with a file portion 31a, a scrap tray 31b, a head insertion portion 31c, a drive box 31f, a scrap box 31g, and a grip portion 31h.

The file portion 31a is a member for notching the neck of the ampoule 10A, and the debris generated by the notch processing in the file portion 31a falls on the debris tray 31b. Specifically, in the mixed injection device 1, the first robot arm 21 holds the ampoule 10A and slides on the ampoule 10A while the neck of the ampoule 10A is in contact with the file portion 31a. Notch processing is applied.

The head insertion portion 31c is located on the side of the hole 31d into which the head of the ampoule 10A having been notched is inserted from below and the head of the ampoule 10A protruding upward from the hole 31d. It has a pusher 31e and a pusher 31e. On the other hand, the drive box 31f has a cam provided inside and a drive motor for driving the cam, and when the cam is driven by the drive motor, the pusher 31e is moved by the cam to the ampoule 10A. It reciprocates in the direction of approaching and separating from the head of the motor.

Then, in the mixed injection device 1, the first robot arm 21 holds the ampoule 10A by the gripping claw 25a, inserts the head of the ampoule 10A into the hole 31d from below, and raises the head above the neck. Protrude to. After that, when the drive motor of the drive box 31f is driven by the second control unit 500 and the pusher 31e is moved in the direction of pushing the head of the ampoule 10A, the head is pushed by the pusher 31e. It is broken. At this time, the head folded by the pusher 31e falls into the waste box 31g. The grip portion 31h is used for the user to grip the ampoule cutter 31 when sliding the ampoule cutter 31 along a rail 31i (see FIG. 4) that slidably supports the ampoule cutter 31.

[Agitator 32]
When the vial bottle 10B contains a chemical that needs to be dissolved, such as powdered medicine (powder), the stirring device 32 injects an infusion solution or a chemical into the vial bottle 10B to dissolve the chemical. Used when producing mixed chemicals. Specifically, the stirring device 32 is used in the stirring step of stirring the chemicals in the vial bottle 10B.

As shown in FIG. 12, the stirring device 32 is provided with a roller 32a, a holding portion 32b, a rotating support portion 32c, a support base 32d, a horizontal swing mechanism 32e, a support portion 32f, a drive motor 32g, and the like. There is. The two rollers 32a are arranged so as to face each other with a predetermined distance from each other. One of the rollers 32a is rotatably supported, and the other roller 32a is connected to the drive motor 32g. Each of the rollers 32a is long in the axial direction, and the stirring device 32 can simultaneously stir the two vial bottles 10B placed on both ends of the roller 32a in the axial direction. ..

Further, the holding portion 32b is a driven roller that is used to hold the vial bottle 10B placed on the roller 32a from above and rotates with the rotation of the vial bottle 10B. The rotation support portion 32c rotates the holding portion 32b in a direction of contacting or separating from the vial bottle 10B by a drive motor (not shown).

The support base 32d supports the roller 32a, the holding portion 32b, the rotation support portion 32c, and the like. The horizontal swing mechanism 32e has, for example, a crank mechanism, and can swing the support base 32d in the axial direction of the roller 32a.

The support portion 32f has U-shaped notches at both ends of the roller 32a in the axial direction into which the neck of the vial bottle 10B is fitted. When the vial bottle 10B is placed on the roller 32a, the neck of the vial bottle 10B is engaged with the notch. As a result, when the support base 32d is swung in the axial direction of the roller 32a by the horizontal rocking mechanism 32e, the vial bottle 10B swings following the axial swing of the roller 32a. , The chemicals in the vial bottle 10B are stirred in the horizontal direction.

On the other hand, when the vial bottle 10B is placed between the two rollers 32a and the drive motor 32g is driven, the vial bottle 10B is rotated by the other roller 32a connected to the drive motor 32g. Then, the chemicals in the vial bottle 10B are stirred. At this time, the one roller 32a rotates in the same direction as the other roller 32a due to the rotation of the vial bottle 10B. Further, if at least one of the rollers 32a is eccentrically driven, the vial bottle 10B placed on the rollers 32a can be stirred in the vertical direction (vertical direction) as well.

[Placement shelf 33]
As shown in FIG. 4, the above-mentioned storage rack 33 is used for temporarily placing the medicine container 10 and the syringe 11 in the mixed injection process performed in the mixed injection device 1. The above-mentioned storage shelf 33 is provided at a position accessible to both the first robot arm 21 and the second robot arm 22. In the above-mentioned storage shelf 33, the vial bottle 10B is placed in a predetermined position in an upright position. On the other hand, the above-mentioned storage shelf 33 is provided with an inclined holding portion for holding the ampoule 10A in an inclined state, and the ampoule 10A is placed on the inclined holding portion in an inclined state. Further, the above-mentioned storage shelf 33 is formed with a neck holding hole having a predetermined diameter in which the neck portion of the syringe 11 is fitted, and the syringe 11 has a neck portion in a state where the injection needle 11c is not attached. Temporarily placed facing down. It is desirable that the size of the above-mentioned storage rack 33 is predetermined by the number of trays 101 that can be accommodated in the accommodation unit 700. For example, the size of the above-mentioned storage shelf 33 allows equipment such as the chemical container 10 and the syringe 11 used in the mixed injection process corresponding to the number of trays 101 that can be accommodated in the storage unit 700 to be placed at the same time. It is possible that the size is large.

[Chemical reading unit 34]
The chemical reading unit 34 reads a bar code written on a label affixed to the chemical container 10 such as the ampoule 10A and the vial bottle 10B and indicating chemical information of the contained chemical. Specifically, the chemical reading unit 34 includes two rollers 34a and a barcode reader 34b, as shown in FIG. The rollers 34a are arranged so as to face each other at a predetermined interval. One of the rollers 34a is rotatably supported, and the other roller 34a is connected to a drive motor (not shown). The two rollers 34a are driven by the drive motor to rotate the chemical container 10 placed between the rollers 34a in the circumferential direction. As a result, the chemical container 10 can be rotated once in the circumferential direction, so that the entire area of the label attached to the chemical container 10 can be directed to the barcode reader 34b. Then, the barcode reader 34b reads the barcode from the label of the chemical container 10 rotated by the roller 34a.

[Weighing meter 35]
The weighing meter 35 is used to measure the weight of the syringe 11 in the mixed injection process performed in the mixed injection device 1, and the measurement result by the weighing meter 35 is input to the second control unit 500. The weighing meter 35 is arranged within the movable range of the second robot arm 22, and measures the weight of the syringe 11 mounted by the second robot arm 22. Further, apart from the weighing meter 35, it is also conceivable that a weighing meter for weighing the medicine container 10 or the syringe 11 or the like is provided on the storage shelf 33 described above.

[Needle bending detection unit 36]
As shown in FIG. 14, the needle bending detection unit 36 is formed with an elongated hole 36a into which the injection needle 11c of the syringe 11 can be inserted and moved. Further, the needle bending detection unit 36 irradiates and receives detection light across the elongated hole 36a, and the first optical sensor 361 and the second optical sensor 362 are arranged so that the detection lights are non-parallel to each other. To prepare for. That is, the irradiation directions of the detection light of the first optical sensor 361 and the second optical sensor 362 are different. The detection results by the first optical sensor 361 and the second optical sensor 362 are input to the second control unit 500.

Then, the injection needle 11c attached to the syringe 11 is inserted into the elongated hole 36a by the second robot arm 22 and moved in the vertical direction. At this time, when the detection light of each of the first optical sensor 361 and the second optical sensor 362 is blocked by the injection needle 11c, the first optical sensor 361 and the second optical sensor 362 are turned off.

As a result, the second control unit 500 can detect bending of the injection needle 11c or the like by using the position information of the injection needle 11c when blocking the detection light. As another embodiment, it is conceivable that the injection needle 11c is photographed with a camera and the needle bending or the like is detected by image recognition for the photographed image. Then, when the injection needle 11c is bent, the second control unit 500 may use the injection needle 11c with the injection needle 11c, for example, based on the bending amount of the injection needle 11c. It is possible to adjust the position of the needle tip when piercing the rubber stopper of the mixed injection port.

[Mixed injection communication port 37]
As shown in FIG. 3, the mixed injection communication port 37 is formed in a dome-shaped portion protruding outward on the side wall of the mixed injection processing chamber 104, and the infusion bag 12 is vertically formed at the dome-shaped portion. A notch is formed to allow the mixed injection port to pass through. Therefore, when the infusion bag holding portion 103 rises, the mixed injection port of the infusion bag 12 is located in the mixed injection processing chamber 104. As a result, the injection needle 11c of the syringe 11 held by the second robot arm 22 can be inserted into the mixed injection port of the infusion bag 12.

[Needle insertion confirmation transparent window 38]
The needle insertion confirmation transparent window 38 is a window in which the infusion bag 12 of the tray transport end portion 110a can be visually recognized from the mixed injection processing unit 300, and the injection needle 11c of the syringe 11 is inserted into the infusion bag 12. It is used when taking an image to check the condition.

[Syringe confirmation camera 42]
Further, as shown in FIG. 6, the syringe confirmation camera 42 is arranged on the ceiling of the mixed injection processing unit 300. Then, the syringe confirmation camera 42 is used to photograph the syringe 11 in order to confirm the presence / absence and amount of the medicine sucked into the syringe 11. The syringe confirmation camera 42 may capture an image within a predetermined imaging range, but the position and size of the imaging range can be arbitrarily changed by being controlled by the second control unit 500. It may be possible. Further, as will be described later, in the mixed injection device 1, the syringe 11 and the drug container 10 are photographed at once by the syringe confirmation camera 42, and a highly credible inspection image is provided. The second control unit 500 has the data storage unit 404 and the data storage unit in order to inspect the captured image taken by the syringe confirmation camera 42, for example, as an image of the suitability of the mixed injection process executed by the mixed injection device 1. The data is recorded in 504 or a storage unit such as a hard disk provided outside the mixed injection device 1. Then, the second control unit 500 causes the display device such as the touch panel monitor 14 or the display 203 to display the image taken by the syringe confirmation camera 42 at the time of the inspection by the user.

[Injection needle attachment / detachment device 43]
In the injection needle attachment / detachment device 43, as shown in FIGS. 15 and 16, the tip of the injection needle 11c to which the cap 11d is attached is inserted into the hole portion 43b of the chuck portion 43a in which the notch portion is formed so as to face upward. When the motor 43c is driven, a cam mechanism (not shown) expands the hole 43b of the chuck portion 43a so that the injection needle 11c can be inserted together with the cap 11d. When the drive of the motor 43c is stopped, the holding state of the cap 11d and the injection needle 11c is maintained by the spring 43d. When the needle turning motor 43e is driven, the gear 43f and the gear 43g are rotated, the chuck portion 43a is rotated, and the cap 11d and the injection needle 11c are rotated.

Each of the injection needle 11c and the cap 11d is provided with a rib that comes into contact with the cap 11d when it is rotated in the circumferential direction while being attached to the injection needle 11c. Therefore, the injection needle 11c rotates together with the cap 11d when the cap 11d of the injection needle 11c is rotated by the chuck portion 43a, and is attached to and detached from the syringe 11a. Further, in the injection needle attachment / detachment device 43, the injection needle is moved toward or separated from the chuck portion 43a by the second robot arm 22 while the cap 11d is held by the chuck portion 43a. It is also possible to automatically attach / detach the cap 11d to / from the 11c. In the injection needle attachment / detachment device 43, since the tip of the injection needle 11c faces upward, the tip opening of the syringe 11a from which the injection needle 11c is removed faces upward, and liquid drips from the neck opening of the syringe 11a. Can be prevented.

[Needle insertion confirmation camera 44]
Further, the needle insertion confirmation camera 44 takes an image of the infusion bag 12 located outside the mixed injection processing chamber 104 and the syringe 11 inside the mixed injection processing chamber 104 so as to fit in one image. When the rubber stopper of the mixed injection port of the infusion bag 12 is punctured by the injection needle 11c, the second control unit 500 photographs the direction of the needle insertion confirmation transparent window 38 by the needle insertion confirmation camera 44. Then, the image captured by the needle insertion confirmation camera 44 is displayed on, for example, the touch panel monitor 14. Here, FIG. 17 is an example of an image taken by the needle insertion confirmation camera 44. Thereby, the user can confirm from the photographed image whether or not the tip end side of the injection needle 11c is located in the infusion bag 12. The captured image is stored in a storage unit such as a hard disk provided inside or outside the mixed injection device 1 for the final inspection, for example. Then, when it is determined that the OK button is operated by the user on the touch panel monitor 14 on which the captured image is displayed and the mixed injection process is appropriately completed, the infusion bag 12 is lowered by the bag elevating portion 113. , Returned to the tray 101.

[Germicidal lamp 45]
The germicidal lamp 45 is turned on, for example, from 3 hours before the start of the mixed injection process. As shown in FIG. 6, one of the two germicidal lamps 45 is provided at a position between the first robot arm 21 and the second robot arm 22. Therefore, the amount of sterilizing light blocked by the first robot arm 21 and the second robot arm 22 is reduced, and the inside of the mixed injection processing chamber 14 can be sterilized evenly. Further, the mixed injection processing unit 300 sucks the air in the mixed injection processing chamber 104 from the slit 104b (see FIGS. 3 and 4) formed in the lower part of the side wall of the mixed injection processing chamber 104, and the mixed injection processing chamber. An exhaust system for exhausting air from an exhaust fan (not shown) provided above the 104 is provided. Further, there is also provided an air supply system that purifies the outside air from the intake port formed on the ceiling of the mixed injection processing chamber 104 and guides the outside air to the mixed injection processing chamber 104 or the like.

Subsequently, the accommodation unit 700 will be described with reference to FIGS. 18 to 21. 18 is a front view of the chemical loading unit 200 and the storage unit 700, FIG. 19 is a sectional view taken along line II in FIG. 18, and FIG. 20 is a sectional view taken along line II-II in FIG. Further, FIG. 21 is a schematic view showing the internal configuration of the accommodation unit 700. In the following, the description may be made using the up / down / left / right and front / back directions shown in FIGS. 18 to 21.

The accommodation unit 700 includes a tray loading unit 710, an elevating unit 800, a tray transport unit 900, and the like, and is controlled by the mixed injection control device 100. The tray loading unit 710 and the elevating unit 800 are arranged behind the work table 202, and the tray transport unit 900 is arranged below the work table 202. A plurality of the trays 101 can be accommodated in the accommodation unit 700, and the mixed injection control device 100 can carry out any of the trays 101 from the accommodation unit 700. The specific configuration of the accommodation unit 700 is not limited to the configuration described here as long as the same function can be achieved.

The tray loading unit 710 includes a shutter 712 for opening and closing the tray loading port 711 used for loading the tray 101 into the accommodating unit 700, and a drive unit 713 used for opening and closing the shutter 712. The drive unit 713 is, for example, a belt conveyor including a motor, a gear, a tension roller, and a belt, and the shutter 712 connected to the belt when the tension roller is rotated by the motor and the gear. Is opened and closed. When the shutter 712 is opened, the user can load the tray 101 into the elevating unit 800 of the accommodating unit 700 by sliding the tray 101 rearward on the work table 202. Become. The tray loading port 711 is arranged at a position vertically separated from the tray discharging port 206, and specifically, the tray loading port 711 is arranged at a position higher than the tray discharging port 206. Has been done.

The elevating unit 800 has a movable housing 810 that is vertically supported so as to be able to move up and down, a plurality of tray accommodating portions 811 arranged in the vertical direction in the moving housing 810, and the tray accommodating portion 811. It is provided with drive units 812 and 813 used for loading and unloading the tray 101, and an elevating mechanism 820 for raising and lowering the moving housing 810 in the vertical direction. The moving housing 810 is supported so as to be slidable in the vertical direction by, for example, a rail portion (not shown) formed on the inner surface of the housing of the housing unit 700. In the moving housing 810, at least the uppermost tray accommodating portion 811 is located above the tray loading port 711, and the lowermost tray accommodating portion 811 is located below the tray loading port 711. It is possible to move up and down between the two states. In particular, in the moving housing 810, the tray 101 can be moved between the tray accommodating portion 811 and the tray carrying unit 710, and the tray accommodating portion 811 and the tray transporting unit 811. The tray 101 moves up and down within a range that can be positioned so that the tray 101 can be moved between the portions 900.

The tray accommodating portion 811 includes a pair of left and right belts 814 capable of supporting the tray 101, a plurality of tension rollers 815 that support each of the belts 814 so as to be runnable, and one of the tension rollers 815. A belt conveyor including a coupled magnet gear 816. The drive unit 812 and the drive unit 813 are motors capable of rotating the magnet gears 812a and 813a in the forward rotation direction and the reverse rotation direction. The magnet gears 812a and 813a can rotate the magnet gears 816 arranged at opposite positions synchronously by magnetic force. That is, the driving force of the driving units 812 and 813 is transmitted from the magnet gears 812a and 813a to the magnet gear 816 of the tray accommodating unit 811 in a non-contact manner. Then, the magnet gear 816 runs the tension roller 815 and the belt 814.

Therefore, in the elevating unit 800, even when the tray accommodating portion 811 having three or more stages is provided, it is possible to drive each of the tray accommodating portions 811 by using the two driving units 812 and 813. .. Therefore, in the mixed injection device 1, dust generation and cost in the elevating unit 800 can be suppressed as compared with the case where a drive unit such as a motor is provided for each tray accommodating unit 811 and the tray moves in the vertical direction. It is possible to reduce the weight of the mobile housing 810.

Here, the magnet gear 812a and the magnet gear 813a are arranged at different positions in the vertical direction. Specifically, the magnet gear 812a is located at a position facing the magnet gear 816 of the tray accommodating portion 811 arranged at a position where the tray 101 can be loaded from the work table 202 via the tray loading port 711. Have been placed. Further, the magnet gear 813a is below the magnet gear 812a, and the tray accommodating portion 811 is arranged at a position where the tray 101 can move between the tray accommodating portion 811 and the tray transport portion 900. Is arranged at a position facing the magnet gear 816.

Thereby, in the storage unit 700, the tray 101 can be transported between the tray storage unit 811 and the tray transport unit 900, for example, by effectively utilizing the area below the work table 202. be. Hereinafter, the position of the tray accommodating unit 811 capable of carrying the tray 101 from the work table 202 to the tray accommodating unit 811 is referred to as a first moving position, and is between the tray accommodating unit 811 and the tray transport unit 900. The position of the tray accommodating portion 811 in which the tray 101 can be moved may be referred to as a second moving position.

The elevating mechanism 820 is a belt conveyor including a motor 821, a pair of left and right belts 822, and a plurality of tension rollers 823. The motor 821 drives each of the belts 822 in the vertical direction by driving the tension roller 823. Each of the belts 822 is connected to the moving housing 810. Then, the elevating mechanism 820 moves the moving housing 810 in the vertical direction by causing each of the belts 822 to travel in the vertical direction by the forward rotation or the reverse rotation of the motor 821.

The tray transport unit 900 includes a first transport unit 910, a second transport unit 920, an IC reader 930, and a third transport unit 940. The first transport unit 910 can transport the tray 101 in the front-rear direction, and the second transport unit 920 can transport the tray 101 in the left-right direction. For example, each of the first transport unit 910, the second transport unit 920, and the third transport unit 940 is a belt conveyor provided with a motor, gears, tension rollers, belts, and the like, and the belt is the motor and the belt. By being driven by the gear and the tension roller, the tray 101 held on the belt can be conveyed.

More specifically, the first transport unit 910 can transport the tray 101 housed in the tray accommodating unit 811 toward the tray discharge port 206. Further, the first transport unit 910 can accommodate the tray 101 in the tray accommodating unit 811. The second transport unit 920 is configured to be movable in the vertical direction, and is in a usable state in which the tray 101 mounted on the first transport unit 910 can be transported in the left-right direction and in the usable state. It is possible to move to and from the retracted state (see FIG. 21) retracted downward from. The third transport unit 940 can transport the tray 101 between the second transport unit 920 and the tray discharge port 701 when the second transport unit 920 is in the usable state.

For example, when the second transport unit 920 shifts from the retracted state to the usable state, the second transport unit 920 moves upward while holding the tray 101 placed at a predetermined position on the first transport unit 910. By moving to, the tray 101 can be transported to and from the third transport unit 930. Further, when the second transport unit 920 shifts from the usable state to the retracted state, the first transport unit 910 holds the tray 101 mounted on the second transport unit 920. The tray 101 is delivered to the first transport unit 910 by moving downward.

As a result, the second transport unit 920 can transport the tray 101 discharged from the tray accommodating unit 811 onto the first transport unit 910 to the third transport unit 940 in the usable state. It is possible. Further, the second transport unit 920 receives the tray 101 supplied from the mixed injection processing unit 300 via the tray discharge port 701 in the usable state via the third transport unit 940, and the tray is described. It can be transported to the first transport unit 910.

The IC reader 930 can read information from the IC tag 101b of the tray 101 mounted on the first transport unit 910 of the tray transport unit 900. The identification information of the tray 101 read from the IC tag 101b by the IC reader 930 is input to the second control unit 500.

As another embodiment, the mixed injection device 1 further includes a stock shelf capable of accommodating a plurality of the trays 101, and the accommodating unit 700 carries the tray 101 into the stock shelf and the stock. A configuration is also conceivable in which the tray 101 can be arbitrarily carried out from the shelf. As a result, a large number of the trays 101 can be temporarily stocked on the stock shelf and automatically discharged as needed. Such a configuration is, for example, when the mixed injection device 1 has a batch preparation inspection function described later, and it is necessary to temporarily stock a plurality of the trays 101 which have not been inspected after the completion of the mixed injection processing. Suitable.

Further, the stock shelf is provided with a door with a key that is opened and closed to take out the tray 101 from a position different from the storage unit 700 side with respect to the individual storage unit in which each of the trays 101 is individually stored. It is possible that it will be done. Thereby, for example, a user can take out each of the trays 101 from the stock shelf as needed and inspect them collectively, and a user who can take out the tray 101 can be specified to hold the key of the door. It is possible to limit to users.

[Mixed injection processing]
Next, an example of a basic processing procedure of the mixed injection processing executed by controlling the mixed injection processing unit 300 by the mixed injection control unit 100 in the mixed injection device 1 will be described. In the mixed injection process, as described below, the second control unit 500 controls the first robot arm 21, the second robot arm 22, and the like, so that one or more of them are based on the preparation data. The drug is sucked from the drug container 10 by the syringe 11, and the drug is injected from the syringe 11 into another container such as the infusion bag 12.

[Mixed injection processing using ampoule 10A]
First, the basic operation of the mixed injection process when injecting the chemical contained in the ampoule 10A into the infusion bag 12 will be described.

When the tray 101 is supplied to the tray transport unit 110, the second control unit 500 reads the identification information of the tray 101 from the IC tag 101b of the tray 101 by the IC reader 101c. Then, the second control unit 500 opens the shutter 111 when the identification information of the tray 101 matches the identification information previously associated with the preparation data of the mixed injection process. After that, the second control unit 500 raises the equipment mounting unit 102 of the tray 101 by the tray elevating unit 112 of the tray transport unit 110 to expose it to the mixed injection processing chamber 104.

Next, the second control unit 500 photographs the equipment mounting unit 102 with the tray confirmation camera 41. The second control unit 500 then performs an image recognition process based on an image captured by the tray confirmation camera 41 to position and orient the ampoule 10A and the syringe 11 mounted on the equipment mounting unit 102. To grasp. In particular, the second control unit 500 photographs the equipment mounting unit 102 with the tray confirmation camera 41 each time the ampoule 10A or the syringe 11 is taken out from the equipment mounting unit 102, and is the latest from the captured image. The position and orientation of the ampoule 10A and the syringe 11 of the above are grasped.

Subsequently, the second control unit 500 places the syringe 11 mounted on the equipment mounting unit 102 exposed in the mixed injection processing chamber 104 by the first robot arm 21 on the above-mentioned storage rack 33. Temporarily place. Further, the second control unit 500 sets the ampoule 10A mounted on the equipment mounting unit 102 in the chemical reading unit 34 by the first robot arm 21. Then, the second control unit 500 reads information such as the type of the drug contained in the ampoule 10A by the drug reading unit 34.

Further, in the second control unit 500, the first injection needle 11c is set in the injection needle attachment / detachment device 43 by the first robot arm 21, and the second injection needle 11c is set in the above-mentioned storage shelf 33. Temporarily place. Here, the first injection needle 11c is an injection needle without a syringe filter, and the second injection needle 11c is an injection needle with a syringe filter. A cap 11d is attached to the injection needle 11c mounted on the equipment mounting portion 102, and the cap 11d is attached / detached by the injection needle attachment / detachment device 43. It is also conceivable that the injection needle 11c is set in the tray 101 in a state of being attached to the syringe 11a of the syringe 11. In this case, the step of setting the syringe 11 on the injection needle 11c is omitted.

Then, when the second control unit 500 takes out all the equipment on the equipment mounting unit 102, the tray elevating unit 112 of the tray transport unit 110 lowers the equipment mounting unit 102 to lower the tray 101. Return to. The second control unit 500 confirms whether or not all the equipment on the equipment mounting unit 102 has been taken out by image recognition processing based on the captured image by the tray confirmation camera 41.

After that, the second control unit 500 closes the shutter 111 and causes the tray transport unit 110 to transport the tray 101 to the tray transport end portion 110a. Next, the second control unit 500 sets the mixed injection port of the infusion bag 12 held by the infusion bag holding unit 103 of the tray 101 by the bag elevating unit 113 of the tray transport unit 110 into the mixed injection processing chamber. It is located at the mixed injection communication port 37 formed in 104.

Then, the second control unit 500 moves the ampoule 10A set in the chemical reading unit 34 to the above-mentioned storage shelf 33 by the second robot arm 22. Next, the second control unit 500 takes out the syringe 11 from the above-mentioned storage rack 33 by the first robot arm 21 and sets it in the second robot arm 22. Subsequently, the second control unit 500 moves the syringe 11 to the injection needle attachment / detachment device 43 by the second robot arm 22 to set the injection needle 11c in the syringe 11. After that, the second control unit 500 moves the syringe 11 to the needle bending detection unit 36 by the second robot arm 22, and detects the presence or absence of bending of the injection needle 11c. It is also conceivable that the injection needle 11c is set in the tray 101 in a state of being attached to the syringe 11. In this case, the step of setting the syringe 11 on the injection needle 11c is omitted.

Next, the second control unit 500 takes out the ampoule 10A from the above-mentioned storage shelf 33 by the first robot arm 21, and uses the ampoule cutter 31 to fold the head of the ampoule 10A. Then, the second control unit 500 brings the ampoule 10A and the syringe 11 close to each other by the first robot arm 21 and the second robot arm 22, and the injection needle 11c of the syringe 11 is brought into the ampoule 10A. Insert inside. After that, the second control unit 500 operates the plunger 11b by the second robot arm 22 to suck a predetermined amount of the drug from the ampoule 10A by the syringe 11.

At this time, the first robot arm 21 and the second robot arm 22 gradually tilt the postures of the ampoule 10A and the syringe 11. For example, with the mouth of the ampoule 10A directed vertically upward and the injection needle 11c of the syringe 11 directed vertically downward, some chemicals are sucked up from the ampoule 10A, and then the ampoule 10A is vertically oriented. It is tilted about 10 degrees with respect to the direction to form a state in which the chemical is moved to the side (neck) of the mouth. This makes it possible to suck up the medicine without leaving the medicine as much as possible without attaching the tip of the injection needle 11c of the syringe 11 to the bottom of the ampoule 10A.

After that, the second control unit 500 controls one or both of the first robot arm 21 and the second robot arm 22 to suck the ampoule 10A and the chemical after the chemical is sucked. The syringe 11 in this state is moved within the imaging range of the syringe confirmation camera 42. Then, the second control unit 500 photographs the ampoule 10A and the syringe 11 at once by the syringe confirmation camera 42, and records the captured images as inspection images in the data storage unit 504. For example, the syringe confirmation camera 42 captures the predetermined imaging range. On the other hand, the syringe confirmation camera 42 so that the ampoule 10A and the syringe 11 after the second control unit 500 is moved by the first robot arm 21 and the second robot arm 22 can be photographed at one time. It is also conceivable that the shooting range of the above can be changed.

Next, the second control unit 500 replaces the injection needle 11c of the syringe 11 by the first robot arm 21 and the second robot arm 22. Specifically, the second control unit 500 moves the syringe 11 to the needle bending detection unit 36 by the second robot arm 22, and detects the presence or absence of bending of the injection needle 11c. Then, the second robot arm 22 moves the syringe 11 to the injection needle attachment / detachment device 43, and attaches the cap 11d to the injection needle 11c. Then, the second control unit 500 rotates the cap 11d by the injection needle attachment / detachment device 43, and removes the injection needle 11c from the syringe 11. The injection needle 11c may be removed by the rotational operation of the cap 11d by the first robot arm 21 and the second robot arm 22.

Then, the second control unit 500 opens the dust lid 132a, and the cap that attaches the injection needle 11c held by the injection needle attachment / detachment device 43 by the first robot arm 21 to the injection needle 11c. It is dropped into the garbage storage chamber 13a together with 11d and discarded. After that, the second control unit 500 causes the injection needle 11c with the syringe filter to be set in the injection needle attachment / detachment device 43 from the above-mentioned storage shelf 33 by the first robot arm 21. Then, the second control unit 500 moves the syringe 11 to the injection needle attachment / detachment device 43 by the second robot arm 22, and attaches the injection needle 11c to the syringe 11. Also in this case, the second control unit 500 moves the syringe 11 to the needle bending detection unit 36 by the second robot arm 22 and detects the presence or absence of bending of the injection needle 11c. As described above, in the mixed injection device 1, the injection needle 11c is exchanged between the time of sucking the chemical from the ampoule 10A and the time of injecting the infusion solution into the infusion bag 12, and the fragments of the ampoule 10A are the fragments of the infusion bag. It is prevented from being mixed with 12.

Then, the second control unit 500 punctures the injection needle 11c of the syringe 11 into the rubber stopper of the mixed injection port of the infusion bag 12 conveyed to the tray transfer end portion 110a by the second robot arm 22. Then, the mixed drug in the syringe 11 is injected into the infusion bag 12. On the other hand, the second control unit 500 opens the dust lid 132a, and the ampoule 10A is dropped into the dust storage chamber 13a by the first robot arm 21 and discarded. Further, the second control unit 500 moves the syringe 11 to the injection needle attachment / detachment device 43 by the second robot arm 22 to attach the cap 11d to the injection needle 11c of the syringe 11. The syringe 11 is dropped into the garbage storage chamber 13a and discarded.

After that, the second control unit 500 executes a preparation inspection process for inspecting the result of the mixed injection process after the completion of the mixed injection process. In the preparation inspection process, the second control unit 500 displays, for example, various captured images captured by the mixed injection process on the touch panel monitor 14, and accepts an operation for completing the inspection for the mixed injection process. As a result, the user can inspect the suitability of the mixed injection process while looking at the touch panel monitor 14. Then, when the second control unit 500 receives the operation of completing the inspection, the tray 101 is conveyed to the tray discharge port 15 so that the tray 101 can be taken out.

[Mixed injection process using vial bottle 10B]
Subsequently, when the chemical contained in the vial bottle 10B is a chemical such as powder that needs to be dissolved, the basics of the mixed injection treatment when the chemical is mixed with the infusion solution and then injected into the infusion bag 12. The operation will be described.

When the tray 101 is supplied to the tray transport unit 110, the second control unit 500 reads the identification information of the tray 101 from the IC tag 101b of the tray 101 by the IC reader 101c. Then, the second control unit 500 opens the shutter 111 when the identification information of the tray 101 matches the identification information previously associated with the preparation data of the mixed injection process. After that, the second control unit 500 raises the equipment mounting unit 102 of the tray 101 by the tray elevating unit 112 of the tray transport unit 110 to expose it to the mixed injection processing chamber 104.

Next, the second control unit 500 photographs the equipment mounting unit 102 with the tray confirmation camera 41. Then, the second control unit 500 determines the position of the equipment such as the vial bottle 10B and the syringe 11 mounted on the equipment mounting unit 102 by the image recognition process based on the image taken by the tray confirmation camera 41. Know the orientation. In particular, the second control unit 500 photographs the equipment mounting unit 102 with the tray confirmation camera 41 each time the vial bottle 10B or the syringe 11 is taken out from the equipment mounting unit 102, and from the captured image. The position and orientation of the latest vial bottle 10B and syringe 11 are grasped.

Subsequently, the second control unit 500 places the syringe 11 mounted on the equipment mounting unit 102 exposed in the mixed injection processing chamber 104 by the first robot arm 21 on the above-mentioned storage rack 33. Temporarily place. Further, the second control unit 500 sets the vial bottle 10B mounted on the equipment mounting unit 102 in the chemical reading unit 34 by the first robot arm 21. Then, the second control unit 500 reads information such as the type of the chemical contained in the vial bottle 10B by the chemical reading unit 34.

Next, when the second control unit 500 takes out all the equipment on the equipment mounting unit 102, the tray elevating unit 112 of the tray transport unit 110 lowers the equipment mounting unit 102 to lower the tray. Return to 101. The second control unit 500 confirms whether or not all the equipment on the equipment mounting unit 102 has been taken out by image recognition processing based on the captured image by the tray confirmation camera 41.

After that, the second control unit 500 closes the shutter 111 and causes the tray transport unit 110 to transport the tray 101 to the tray transport end portion 110a. Next, the second control unit 500 sets the mixed injection port of the infusion bag 12 held by the infusion bag holding unit 103 of the tray 101 by the bag elevating unit 113 of the tray transport unit 110 into the mixed injection processing chamber. It is located at the mixed injection communication port 37 formed in 104.

Then, the second control unit 500 moves the vial bottle 10B set in the chemical reading unit 34 to the above-mentioned storage shelf 33 by the second robot arm 22. On the other hand, in parallel with this movement process, the second control unit 500 uses the first robot arm 21 to attach the injection needle 11c of the syringe 11 mounted on the equipment mounting unit 102 to the cap 11d. The injection needle attachment / detachment device 43 is set in the attached state.

Next, the second control unit 500 takes out the syringe 11 from the above-mentioned storage rack 33 by the first robot arm 21 and sets it in the second robot arm 22. Subsequently, the second control unit 500 moves the syringe 11 to the injection needle attachment / detachment device 43 by the second robot arm 22 to set the injection needle 11c in the syringe 11. After that, the second control unit 500 moves the syringe 11 to the needle bending detection unit 36 by the second robot arm 22, and detects the presence or absence of bending of the injection needle 11c. It is also conceivable that the injection needle 11c is set in the tray 101 in a state of being attached to the syringe 11a of the syringe 11. In this case, the step of setting the syringe 11 on the injection needle 11c is omitted.

Subsequently, the second control unit 500 pierces the injection needle 11c of the syringe 11 into the rubber stopper of the mixed injection port of the infusion bag 12 conveyed to the tray transfer end portion 110a by the second robot arm 22. Then, the infusion solution in the dissolved amount shown in the preparation data is sucked from the infusion solution bag 12. On the other hand, the second control unit 500 takes out the vial bottle 10B mounted on the above-mentioned storage shelf 33 by the first robot arm 21.

Then, the second control unit 500 brings the vial bottle 10B and the syringe 11 closer to each other by the first robot arm 21 and the second robot arm 22, and the injection needle 11c of the syringe 11 is used. Puncture the vial bottle 10B. After that, the second control unit 500 injects the infusion solution in the syringe 11 into the vial bottle 10B by operating the plunger 11b by the second robot arm 22. As described above, when the drug is a powdered drug, in the mixed injection process, a dissolution step of extracting the infusion solution from the infusion bag 12 with the syringe 11 and injecting the infusion solution from the syringe 11 into the vial bottle 10B is executed. Will be done. As a result, the chemicals in the vial bottle 10B are dissolved in the infusion solution. At this time, the postures of the syringe 11 and the vial bottle 10B are such that the injection needle 11c of the syringe 11 is directed vertically downward and the mouth of the vial bottle 10B is directed vertically upward.

Next, the second control unit 500 sets the vial bottle 10B into which the infusion solution has been injected in the stirring device 32 by the first robot arm 21. As a result, in the stirring device 32, a stirring step in which the chemicals and the infusion solution in the vial bottle 10B are stirred is executed. The stirring time in the stirring step is predetermined, for example, depending on the type of the chemical. Further, the stirring time may be predetermined for each combination of the chemical and the infusion solution, or may be changed depending on the amount of the chemical in the vial bottle 10B. When the stirring step by the stirring device 32 is completed, the second control unit 500 takes out the vial bottle 10B from the stirring device 32 by the first robot arm 21.

Here, the second control unit 500 executes a stirring inspection process for inspecting the stirring result by the stirring step after the completion of the stirring step. In the stirring inspection process, the second control unit 500 controls the first robot arm 21 to move the vial bottle 10B to a posture and position where the bottom or side surface of the vial bottle 10B can be visually recognized by the user. , Waits for the user to confirm the touch panel monitor 14 and the like. Further, the second control unit 500 controls the first robot arm 21 in response to a predetermined operation on the touch panel monitor 14, so that the user can visually recognize the bottom or side surface of the vial bottle 10B from different angles. A rocking process for moving the vial bottle 10B to a plurality of states (posture and position) is performed. This allows the user to check the degree of dissolution of the chemical in the vial bottle 10B from different angles.

After that, when the confirmation operation is performed, the second control unit 500 advances the processing step of the mixed injection process to the next. On the other hand, when the predetermined re-stirring operation is performed, the second control unit 500 sets the vial bottle 10B in the stirring device 32 again without proceeding with the processing step of the mixed injection process, and said the above. Re-execute the stirring step. In the stirring inspection process, the second control unit 500 may display a photographed image of the bottom or side surface of the chemical container 10 photographed after the stirring step on the touch panel monitor 14.

Then, the second control unit 500 brings the vial bottle 10B and the syringe 11 closer to each other by the first robot arm 21 and the second robot arm 22, and the injection needle 11c of the syringe 11 is used. Puncture the vial bottle 10B. After that, the second control unit 500 operates the plunger 11b by the second robot arm 22 to suck the mixed drug in the vial bottle 10B with the syringe 11. At this time, the postures of the syringe 11 and the vial bottle 10B are such that the mouth of the vial bottle 10B is directed vertically downward and the injection needle 11c of the syringe 11 is directed vertically upward.

After that, the second control unit 500 controls one or both of the first robot arm 21 and the second robot arm 22 to suck the medicine into the vial bottle 10B and the medicine. The aspirated syringe 11 is moved within the imaging range of the syringe confirmation camera 42. Then, the second control unit 500 photographs the vial bottle 10B and the syringe 11 at once by the syringe confirmation camera 42, and records the captured images as inspection images in the data storage unit 504. For example, the syringe confirmation camera 42 captures the predetermined imaging range. On the other hand, the syringe confirmation camera so that the vial bottle 10B and the syringe 11 after the second control unit 500 is moved by the first robot arm 21 and the second robot arm 22 can be photographed at one time. It is also conceivable that the shooting range of 42 can be changed.

Then, the second control unit 500 punctures the injection needle 11c of the syringe 11 into the rubber stopper of the mixed injection port of the infusion bag 12 conveyed to the tray transfer end portion 110a by the second robot arm 22. Then, the mixed drug in the syringe 11 is injected into the infusion bag 12. As described above, in the mixed injection process, an injection step of sucking the drug from the vial bottle 10B with the syringe 11 and injecting the drug from the syringe 11 into the infusion bag 12 is executed.

On the other hand, the second control unit 500 opens the dust lid 132a and drops the vial bottle 10B into the dust storage chamber 13a by the first robot arm 21 for disposal. Further, the second control unit 500 moves the syringe 11 to the injection needle attachment / detachment device 43 by the second robot arm 22 to attach the cap 11d to the injection needle 11c of the syringe 11. The syringe 11 is dropped into the garbage storage chamber 13a and discarded.

After that, the second control unit 500 executes a preparation inspection process for inspecting the result of the mixed injection process after the completion of the mixed injection process. In the preparation inspection process, the second control unit 500 displays, for example, various captured images captured by the mixed injection process on the touch panel 14, and accepts an operation for completing the inspection for the mixed injection process. As a result, the user can inspect the suitability of the mixed injection process while looking at the touch panel monitor 14. Then, when the second control unit 500 receives the operation of completing the inspection, the tray 101 is conveyed to the tray discharge port 15 so that the tray 101 can be taken out.

It is also conceivable that the chemical contained in the vial bottle 10B is a chemical such as a chemical solution that does not need to be dissolved. The mixed injection treatment in this case is the same as the mixed injection treatment when the chemical contained in the vial bottle 10B is a chemical such as a powdered medicine that needs to be dissolved, except that the stirring step is not executed. Therefore, the description is omitted. Further, even when the chemical contained in the vial bottle 10B is a liquid, the stirring step may be executed depending on the type of the chemical.

Further, in the mixed injection process when the drug solution contained in the vial bottle 10B is directly injected into the infusion bag 12, the mixed drug in which the infusion solution is sucked from the infusion bag 12 and injected into the vial bottle 10B and stirred is used. It is the same as the mixed injection process when injecting the powder contained in the vial bottle 10B into the infusion bag 12 except that the step for producing is not performed.

Hereinafter, with reference to FIGS. 22 to 29, an example of a procedure of the mixed injection management process, the loading preparation process, the mixed injection start process, and the mixed injection control process executed by the mixed injection control unit 100 in the mixed injection device 1 will be described. ..

[Mixed injection management process]
First, the mixed injection management process will be described with reference to FIG. 22.

<Step S10>
In step S10, the first control unit 400 generates a prescription selection screen M1 on which selection candidates of the preparation data to be the target of the mixed injection processing in the mixed injection device 1 are arranged, and displays the prescription selection screen M1 on the display 203. Here, when there are a plurality of selection candidates for the preparation data to be mixed injection processing in the mixed injection device 1, the preparation data of the selection candidates are arranged according to preset sorting conditions on the prescription selection screen M1. It is displayed in the state. The sort condition is determined by, for example, any one or a combination of the preparation date and time, the medication date and time, the prescription classification, and the issuance date and time of the preparation data by the mixed injection device 1. Then, the user refers to the prescription selection screen M1 and uses the mixed injection device 1 to display the required number of the drug containers 10 and the syringe 11 in the preparation data displayed at the top of the prescription selection screen M1. The tray 101 is placed on the tray 101, and the tray 101 is loaded into the mixed injection processing unit 300.

Here, FIG. 23 is a diagram showing an example of the prescription selection screen M1. On the prescription selection screen M1 shown in FIG. 23, a search condition display unit D1 in which an input field for search conditions for narrowing down the selection candidates is arranged, and a prescription display unit in which the preparation data of the selection candidates are arranged side by side. D2 and the like are included. In the search condition display unit D1, an extraction key D11 for starting an extraction process for narrowing down selection candidates of the preparation data according to the search conditions is arranged.

Further, the prescription display unit D2 displays whether or not the prescription drug contains preparation data of the same type as the residual drug remaining in the drug container 10 in the mixed injection process executed in the past. The drug presence / absence display unit D21 is included. That is, the residual drug presence / absence display unit D21 indicates whether or not the preparation data is capable of executing the mixed injection process using the residual drug. For example, the residual drug presence / absence display unit D21 indicates whether or not the residual drug is usable preparation data by information such as characters, symbols, figures, or illustrations.

By the way, there may be a case where it is not necessary to use the residual drug in the other mixed injection treatment. Therefore, the first control unit 400 can change the ON / OFF of the residual drug use function for using the residual drug generated in the past mixed injection process in another mixed injection process according to the user operation in the initial setting or the like. Is. This allows the user to optionally switch whether or not to receive support for using the residual drug in the other mixed injection process. The first control unit 400 may be configured to be able to switch ON / OFF of the residual drug use function according to the user operation on the prescription selection screen M1. Then, when the residual drug use function is ON, the first control unit 400 executes the process after step S16 described later, and when the residual drug use function is OFF, the process after step S16 described later. It is conceivable that the processing of is not executed. Further, when the residual drug use function is OFF, the first control unit 400 may hide the residual drug presence / absence display unit D21 on the prescription selection screen M1.

The first control unit 400 has a sort condition setting function for setting the sort condition according to a user operation on the operation unit 405 in the initial setting or the like. For example, the first control unit 400 can change the sort condition to change the display order of the preparation data also on the prescription selection screen M1. That is, when the description location of each display item of the prescription display unit D2 is operated by the mouse or the touch panel of the operation unit 405, the first control unit 400 assigns the operated display items in ascending or descending order. It is possible to rearrange the preparation data so that

<Step S11>
In step S11, the first control unit 400 determines whether or not the preparation data has been input. For example, the preparation data is input to the first control unit 400 when the preparation data is received from the host system 600 or when the barcode indicating the preparation data is read by the barcode reader 204.

Here, when the first control unit 400 determines that the preparation data has been input (Yes side of S11), the process shifts to step S12, and if the preparation data has not been input (No side of S11). , The process shifts to step S13.

<Step S12>
In step S12, the first control unit 400 stores the prepared data determined to have been input in step S11 in the data storage unit 404. Further, when the prescription selection screen M1 is displayed, the first control unit 400 updates the display contents of the prescription selection screen M1 at any time.

<Step S13>
Then, in step S13, the first control unit 400 determines whether or not an extraction start operation for extracting specific preparation data from the preparation data of the selection candidate has been performed. Specifically, the first control unit 400 sets the search condition in the search condition display unit D1 by a user operation on the operation unit 405, and the extraction key D11 is operated according to whether or not the extraction key D11 is operated. Determine if there is a start operation.

Here, when the first control unit 400 determines that the extraction start operation has been performed (Yes side of S13), the process shifts to step S131, and if the extraction start operation has not been performed (No side of S13). , The process shifts to step S14.

<Step S131>
In step S131, the first control unit 400 extracts the preparation data as a selection candidate according to the search conditions. For example, in the prescription selection screen M1 shown in FIG. 23, "2012/07/12" is input in the dispensing date input field indicating the scheduled execution date of the mixed injection process, and the result of the extraction of the preparation data is executed. This is the displayed example.

<Step S132>
In step S132, the first control unit 400 displays the prescription selection screen M1 on which the preparation data extracted in step S131 is arranged, and returns the process to the step S11. For example, the prescription selection screen M1 shown in FIG. 23 displays a plurality of the preparation data extracted in the step S131 when it is preset to display the dosing dates in order from the top. This is an example.

<Step S14>
On the other hand, in step S14, the first control unit 400 determines whether or not a user operation for selecting any of the preparation data has been performed on the operation unit 405. Here, when the first control unit 400 determines that the preparation data selection operation has been performed (Yes side of S14), the process shifts to step S15 until the preparation data selection operation is performed. (No side of S14) shifts the process to step S11.

<Step S15>
In step S15, the first control unit 400 transmits the preparation data selected by the selection operation in step S14 to the second control unit 500. The first control unit 400 is not limited to the preparation data itself, but generates mixed injection control data for causing the mixed injection processing unit 300 to execute the mixed injection processing based on the preparation data, and the mixed injection control data is used as described above. It may be transmitted to the second control unit 500.

<Step S16>
Next, in step S16, the chemical remains in the chemical container 10 used when the mixed injection treatment for the preparation data selected in step S14 is performed in the first control unit 400. Decide whether to do it or not. Specifically, the first control unit 400 has the predetermined amount in the chemical container 10 based on the dispensed amount of the chemical based on the preparation data and the predetermined amount of the chemical contained in the chemical container 10. Whether or not less than the amount of chemicals remains is determined before the end of the mixed injection treatment. As a result, even before the mixed injection process is completed, adjustment data that can use the residual drug when displaying the selection candidate to be the target of the next mixed injection process in step S181 or step S19 described later is displayed. It is possible to display with priority.

For example, when the dispensed amount of the medicine is 20 ml and the predetermined amount of the medicine container 10 is 30 ml, the first control unit 400 has 30 ml, which is the default amount of one medicine container 10, and the dispensed amount. Based on the difference from 40 ml, it is determined that 10 ml of the chemical remains in the chemical container 10. When the dispensed amount of the chemical is 40 ml and the predetermined amount of the chemical container 10 is 30 ml, the first control unit 400 has 60 ml, which is the total amount of the two chemical containers 10, and the dispensed amount. Based on the difference from 40 ml, it is determined that 20 ml of the chemical remains in the chemical container 10.

Here, when the first control unit 400 determines that the chemical remains in the chemical container 10 (Yes side of S16), the process is shifted to step S17, and it is determined that the chemical does not remain in the chemical container 10. Then (No side of S16), the process shifts to the step S11. In this way, the first control unit 400 determines whether or not the chemical remains in the chemical container 10 when the mixed injection treatment is completed before the mixed injection processing is completed. Therefore, the processes after step S17 are executed before the user starts preparing the chemicals and instruments necessary for the next mixed injection process. In addition, it is also considered as another embodiment that it is determined whether or not the chemicals in the chemical container 10 remain after the completion of the mixed injection treatment.

<Step S17>
In step S17, the first control unit 400 stores the residual drug information regarding the residual drug determined to remain in step S16 in the data storage unit 404. Specifically, the residual drug information includes various information such as, for example, the type of the residual drug, the remaining amount, the opening date and time, and the expiration date. When the residual drug is a mixed drug, the residual drug information includes, for example, various information such as the components (drug name, solvent name) of the mixed drug, the amount of the solvent, the remaining amount, the opening date and time, and the expiration date. included. The residual drug information also includes position information on the pre-described shelf 33 on which the drug container 10 containing the residual drug is placed. Here, the data storage unit 404 is an example of the remaining amount storage means. In the mixed chemicals, since the mixing ratio in the mixed chemicals is specified according to the chemical name and the solvent amount, a case where the solvent amount is stored as the residual information will be described as an example. The mixing ratio may be stored.

By the way, the first control unit 400 deletes each of the remaining drug information stored in the data storage unit 404 on condition that the expiration date of the remaining drug information has passed, and the remaining drug information is used. It is conceivable to input a control signal for discarding the corresponding drug container 10 to the second control unit 500. As a result, the second control unit 500 controls the first robot arm 21 or the second robot arm 22 to dispose of the chemical container 10 whose expiration date has passed. At this time, the first control unit 400 sets the display order of the preparation data on the prescription display unit D2 displayed on the prescription selection screen M1 in the case where the residual drug whose expiration date has passed does not exist. Update in the display order of.

<Step S18>
Subsequently, in step S18, the first control unit 400 determines whether or not the residual drug remaining in the drug container 10 is a mixed drug in which a plurality of drugs or solvents are mixed. Here, when the first control unit 400 determines that the residual drug is the mixed drug (Yes side of S18), the process shifts to step S19, and determines that the residual drug is not the mixed drug. (No side of S18), the process is shifted to step S181.

<Step S181>
In step S181, the first control unit 400 is a residual drug determined to remain in the drug container 10 in the past mixed injection process by the step S16 among the selection candidates of the prepared data to be the target of the mixed injection process. Priority is given to the preparation data in which the same type of drug is included as a prescription drug. Here, the first control unit 400 when executing the display process corresponds to the display control means. Specifically, the first control unit 400 is a selection candidate for the preparation data in the display order in which the selection candidates for the preparation data containing the same type of drug as the residual drug remaining in the drug container 10 as a prescription drug are ranked higher. Is displayed on the prescription selection screen M1 of the display 403. In addition, the first control unit 400 uses the residual drug in the residual drug presence / absence display unit D21 corresponding to the preparation data in which a drug of the same type as the residual drug remaining in the drug container 10 is contained as a prescription drug. Display information indicating that is possible. This allows the user to easily grasp the preparation data in which the residual drug can be used. In particular, in the mixed injection device 1, the preparation data that can use the residual drug remaining in the previous mixed injection process is preferentially displayed as a selection candidate for the next mixed injection process, so that the user can use the residual drug. The prepared data that can be prepared can be made aware of as the target of the next mixed injection treatment, and the efficient use of the drug in the drug container 10 can be supported.

For example, in step S181, the first control unit 400 searches for preparation data containing a drug of the same type as the residual drug remaining in the drug container 10 as a prescription drug. Then, when one or more of the preparation data are obtained as a search result, the first control unit 400 changes the display content of the prescription selection screen M1 so that the display position of the preparation data is at the highest level. Further, as a method for preferentially displaying preparation data in which a drug of the same type as the residual drug remaining in the drug container 10 is contained as a prescription drug, the first control unit 400 remains in the drug container 10. It is also conceivable to display only the preparation data containing the same type of drug as the residual drug as a prescription drug on the display device 26. Thereby, the user can easily confirm only the preparation data in which the residual drug can be used.

Here, when there are a plurality of preparation data extracted as the search result, the first control unit 400 determines the order of the plurality of preparation data according to the sort condition, as in step S12. Thereby, it is possible to display the candidate of the preparation data to be prioritized according to the sort condition at the top. As described above, the sort condition is, for example, a condition in which the dosing date / time or the preparation date / time of the prescription drug in the preparation data is earlier. It is also conceivable that the sort condition is higher when the prescription category of the preparation data is outpatient than when the prescription category of the preparation data is hospitalized. As a result, the user can easily grasp the order of the dispensing data to be prioritized according to the dosing date / time, the preparation date / time, the prescription classification, and the like.

If the preparation data containing a drug of the same type as the residual drug remaining in the drug container 10 as a prescription drug is not extracted, the first control unit 400 does not change the display content of the prescription selection screen M1. Can be considered. In this case, the first control unit 400 determines that the remaining medicine cannot be used, and instead of placing the medicine container 10 on the above-mentioned storage shelf 33, the medicine container 10 is stored in the garbage. It is also conceivable to transmit a control signal for disposal to the chamber 13a to the second control unit 500.

<Step S19>
On the other hand, in step S19, the first control unit 400 preferentially displays the preparation data containing the prescription drug having the same composition and mixing ratio as the mixed drug which is the residual drug remaining in the drug container 10. .. Here, the first control unit 400 when executing the display process corresponds to the display control means. At this time, the first control unit 400 determines whether or not the mixing ratio is the same according to, for example, the drug name and the solvent amount stored in the residual information and the drug name and the solvent amount in the preparation data. do.

Specifically, the first control unit 400 displays the preparation data in which the prescription drug contains a drug having the same composition and mixing ratio as the residual drug remaining in the drug container 10, as in the step S181. In order, the selection candidates of the preparation data are displayed on the prescription selection screen M1 of the display 403. Further, the first control unit 400 displays the residual drug on the residual drug presence / absence display unit D21 corresponding to the preparation data in which the drug having the same component and mixing ratio as the residual drug remaining in the drug container 10 is included as a prescription drug. Display information indicating that it is possible to use. In step S19 as well, when a plurality of the preparation data are present, the first control unit 400 determines the order of the plurality of preparation data according to the sort condition, as in the case of step S181.

[Pre-stirring function]
By the way, the stirring step that may be executed in the mixed injection process may take a relatively long time, and the waiting time until the stirring step is completed may hinder the efficiency of the mixed injection process. .. On the other hand, the mixed injection device 1 according to the present embodiment has a pre-stirring function capable of executing the stirring step in the mixed injection process in advance before the execution start timing of the mixed injection process. Specifically, the mixed injection control unit 100 uses the first control unit 400 or the second control unit 500 to perform the loading preparation process and the mixed injection start described later according to the first mixed injection control program or the second mixed injection control program. By executing the process, the pre-stirring function is realized. Here, the mixed injection control device 100 when executing the loading preparation process and the mixed injection start process is an example of the pre-stirring processing unit. The first control unit 400 and the second control unit 500 may effectively set the pre-stirring function when the chemical container 10 is the vial bottle 10B.

[Preparation for loading]
First, with reference to FIG. 24, an example of the loading preparation process executed by the first control unit 400 and the second control unit 500 of the mixed injection control device 100 will be described.

<Step S21>
In step S21, the first control unit 400 waits for a loading preparation start operation using the operation unit 405 by the user (S21: No). For example, the first control unit 400 determines that the loading preparation start operation has been performed when the preparation data to be loaded is selected by the user. Then, when the loading preparation start operation is performed (S21: Yes), the process proceeds to step S22.

By the way, as the loading preparation start operation, the first control unit 400 receives an immediate start operation for immediately executing the mixed injection process based on the preparation data, and the completion time or completion time of the mixed injection process for the preparation data. It is possible to accept a reserved mixed injection operation that reserves a scheduled completion time indicating a band or the like. When the completion time zone is reserved, an hourly reservation is accepted as a time range in which the mixed injection process should be completed, for example, between 11:00 and 12:00. For example, the first control unit 400 can set the reservation of the preparation data which is the same as the number of the tray accommodating units 811 and is equal to or less than the preset maximum reservation number. The reservation process is not limited to the start of the load preparation process, but may be executed at the end of the load preparation process.

When the scheduled completion time is set, the first control unit 400 automatically estimates the time required for the mixed injection process based on the preparation data, and subtracts the required time from the scheduled completion time. It is set as the execution start timing of the mixed injection process. For example, the required time is calculated based on the required time table information stored in the data storage unit 404. In the required time table, the required time of each step of the mixed injection process is preset for each content of the mixed injection process as information for calculating the required time according to the content of the mixed injection process.

Further, the first control unit 400 may accept reservations for the preparation data not only at the scheduled completion time but also at the scheduled start time indicating the start time or the completion time zone of the mixed injection process. good. When the start time zone is reserved, an hourly reservation is accepted as a time range in which the mixed injection process should be started, for example, between 11:00 and 12:00. For example, when the scheduled start time is set for the preparation data, the first control unit 400 sets the scheduled start time as the execution start timing of the mixed injection process. Further, as a time range from the start to the completion of the mixed injection process, it is conceivable that reservations for the execution time zone may be accepted in units of one hour, for example, between 11:00 and 12:00. When the execution time zone is set for the preparation data, the first control unit 400 sets the execution start timing of the mixed injection process so that the mixed injection process is completed within the execution time zone. The first control unit 400 may be able to reserve only the mixed injection process for one of the prepared data. Further, the reservation target is not limited to the scheduled completion time, the scheduled start time, or the execution time of the mixed injection process, and the completion of the injection step of injecting the drug solution collected from the drug container 10 into the infusion bag 12 in the mixed injection process. Scheduled time, scheduled start time, and execution time zone may be reserved.

<Step S22>
In step S22, the first control unit 400 executes a process of associating the prepared data selected as a processing target with the tray 101 and storing them in the correspondence information D31 (an example of the first correspondence information). Here, the first control unit 400 when executing the storage process is an example of the first storage process unit. Further, the corresponding information D31 of the data storage unit 404 of the first control unit 400 can also be referred to and edited by the second control unit 500. Thereby, the first control unit 400 and the second control unit 500 can recognize the correspondence relationship between the preparation data and the tray 101 based on the correspondence information D31.

FIG. 25 is a diagram showing an example of the corresponding information D31. As shown in FIG. 25, in the corresponding information D31, the identification information “preparation No.” of the preparation data and the identification information “tray ID” of the tray 101 are associated with each other. Further, in the corresponding information D31, information such as a drug name, a payout amount, and a predetermined amount of the drug used in the mixed injection process based on the preparation data is also associated with each of the preparation data.

For example, the first control unit 400 uses the IC reader 207 provided on the work table 202 to identify information of the tray 101 from the IC tag 101b of the tray 101 placed on the work table 202. To read. Then, the first control unit 400 uses the identification information read from the IC tag 101b as the identification information of the tray 101 corresponding to the preparation data selected as the processing target, and the correspondence of the data storage unit 404. It is stored in the information D31.

Further, in the corresponding information D31, the identification information “accommodation unit No.” of the tray accommodating unit 811 of the accommodating unit 700, which is associated with each of the trays 101 in step S31 described later, is also stored. As a result, the first control unit 400 and the second control unit 500 can recognize the preparation data, the identification information of the tray 101, and the correspondence relationship of the tray accommodating unit 811 based on the correspondence information D31. It is possible.

Further, in the corresponding information D31, the chemical presence / absence information indicating whether or not the chemical container 10 of the chemical used in the mixed injection processing based on the preparation data is stored in the tray 101 corresponding to each of the preparation data is also stored. ing. The chemical presence / absence information is, for example, when the chemical container 10 is placed on the tray 101 (step S25 described later), or when the chemical container 10 is taken in from the tray 101, the first control unit 400 or It is updated by the second control unit 500. Thereby, the first control unit 400 or the second control unit 500 can determine the presence or absence of the chemical container 10 in the tray 101 by using the corresponding information D31.

The correspondence between the preparation data and the tray 101, and the correspondence between the preparation data or the tray 101 and the tray accommodating portion 811 may be managed in individual databases. Further, the correspondence between the preparation data and the tray 101 is stored in the data storage unit 404 of the first control unit 400, and the correspondence between the preparation data or the tray 101 and the tray accommodating unit 811 is the second. It may be stored in the data storage unit 504 of the control unit.

<Step S23>
After that, in steps S23 to S28, the first control unit 400 sets the medicine container 10, the syringe 11, the infusion bag 12, and the like necessary for the mixed injection process based on the preparation data in the tray 101. Perform processing to assist. Specifically, first, in step S23, the first control unit 400 adds a message, an image, or the like for instructing reading of identification information such as the GS21 data bar attached to the infusion bag 12 to the prepared data. It is displayed on the display 203 together with information including the type of the infusion bag 12 included. Then, when the identification information of the infusion bag 12 is read by the bar code reader 204 and the collation result with the prepared data matches, the first control unit 400 shifts the process to step S24. If the identification information of the infusion bag 12 and the collation result of the preparation data do not match, the first control unit 400 displays, for example, an error message.

<Step S24>
In step S24, the first control unit 400 causes the display 203 to display a message, an image, or the like for guiding the arrangement of the infusion bag 12 on the tray 101. This allows the user to easily place the infusion bag 12 in a predetermined position in the tray 101.

<Step S25>
In step S25, the first control unit 400 includes a message, an image, and the like for instructing reading of identification information such as the GS21 data bar attached to the chemical container 10 in the preparation data. It is displayed on the display 203 together with information including 10 types and the like. Then, when the identification information (drug code or the like) of the chemical container 10 is read by the barcode reader 204 and the collation result with the preparation data matches, the first control unit 400 shifts the process to step S26. .. Further, the first control unit 400 stores the information that the chemical container 10 is placed on the tray 101 corresponding to the preparation data in the corresponding information D31. If the identification information of the chemical container 10 and the collation result of the preparation data do not match, the first control unit 400 displays, for example, an error message.

Further, when the loading start operation is performed in step S21, the first control unit 400 is already loaded in the mixed injection device 1 instead of reading the identification information attached to the chemical container 10. It is possible to accept operations for using the chemicals in the chemical container 10. As described above, the loading preparation start operation includes an immediate start operation for immediately executing the mixed injection process based on the preparation data, or a completion time or time zone for the mixed injection process for the preparation data. Includes a reserved mixed injection operation that reserves the indicated scheduled completion time.

Specifically, the first control unit 400 is in the mixed injection device 1 at a preset reference time point for a chemical of the same type as the chemical in the chemical container 10 used in the mixed injection processing based on the preparation data to be processed. It is determined whether or not the amount of residual liquid remaining in the above is greater than or equal to the amount of chemicals required for the mixed injection treatment based on the preparation data. For example, the reference time point is when the mixed injection process based on the preparation data is started or when the loading start operation for the preparation data is performed. Then, when the residual liquid amount is equal to or more than the amount of chemicals required for the mixed injection process based on the preparation data, the first control unit 400 selects whether or not to use the chemicals already existing in the mixed injection device 1. The available residual liquid guidance screen F1 (see FIG. 37), which will be described later, is displayed on the display 203. For example, the available residual liquid guidance screen F1 is displayed on a display screen on which a message or the like for instructing reading of the identification information attached to the chemical container 10 is displayed or before the display screen is displayed. Will be done. For example, the first control unit 400 may display the available residual liquid guide screen F1 when it is determined in step S25 that the identification information of the chemical container 10 has been read by the barcode reader 204. .. The available residual liquid guide screen F1 may be displayed regardless of whether or not the amount of residual liquid remaining in the mixed injection device 1 is equal to or greater than the amount of chemicals required for the mixed injection process based on the preparation data. .. Further, the available residual liquid guidance screen F1 may be displayed according to the user operation. Here, the first control unit 400 determines whether or not a drug used in the mixed injection process based on the prepared data to be processed exists in the mixed injection device 1 based on the residual drug information and the corresponding information D31. To judge. That is, the residual drug information and the corresponding information D31 can be used as inventory information indicating a list of drugs already loaded in the mixed injection device 1.

Here, FIG. 37 is a diagram showing an example of the available residual liquid guide screen F1. As shown in FIG. 37, on the available residual liquid guidance screen F1, areas A11 to A13, operation keys K11, operation keys K12, and the like are displayed. In the area A11, drug identification information such as a drug name of a drug contained as a prescription drug in the preparation data currently being processed (hereinafter referred to as target preparation data) and a drug corresponding to the drug identification information. The amount of residual liquid is displayed. Further, the prescription amount of the drug corresponding to the drug identification information in the target preparation data may be displayed in the area A11. In the area A12, an image showing the appearance of a drug such as a drug container 10 containing a drug contained as a prescription drug in the target adjustment data and a drug box containing the drug container 10 is displayed. In the area A13, a message indicating that the residual liquid can be used for the drug contained as a prescription drug in the target preparation data is displayed. The first control unit 400 sends information as an index for the user to determine whether or not the chemical container 10 needs to be placed on the tray 101 to the available residual liquid guide screen F1. It is conceivable to notify the user by displaying. For example, the first control unit 400 may display a message on the available residual liquid guidance screen F1 indicating that the residual liquid amount is equal to or larger than the prescribed amount of the drug shown in the target preparation data. .. Further, the first control unit 400 does not place the chemical container 10 on the tray 101 corresponding to the target preparation data, and uses only the chemical with the residual liquid amount to perform mixed injection processing based on the target preparation data. May display on the available residual liquid guidance screen F1 a message indicating that is feasible.

The residual liquid amount displayed in the region A11 is the total amount of the chemicals remaining in the mixed injection device 1 when the mixed injection process based on the target preparation data is executed. More specifically, the residual liquid amount is based on the remaining amount of the chemicals placed on the storage shelf 33 described above at the time when the loading start operation is performed on the target preparation data and the target preparation data. From the sum of the amount of the drug loaded into the mixed injection device 1 with the other preparation data corresponding to one or more other mixed injection processes performed before the mixed injection process is performed. It is the amount obtained by subtracting the total amount (total of prescription amounts) of the chemicals used in one or more other mixed injection processes executed until the mixed injection process based on the target preparation data is executed. In particular, the residual liquid amount is the amount of the chemical whose expiry date does not come at the start of the mixed injection treatment based on the target preparation data, and the amount of the chemical whose expiry date comes at the start of the mixed injection treatment is a subtracted value. It can be thought that. The unit of the residual liquid amount may be weight or volume, but is not limited to these, and is not limited to these, for example, based on a predetermined amount of the chemical contained in the specific chemical container 10 set in advance. , The residual liquid amount may be displayed in units of the number of the chemical containers 10.

Here, the residual liquid amount will be described with an example. Here, FIG. 38 (A) shows an example of the residual drug information, and FIG. 38 (B) shows an example of the corresponding information D31. Then, in this state, the loading start operation for the target preparation data is performed, and the mixed injection process based on the target preparation data is executed after the mixed injection process based on the other preparation data registered in the corresponding information D31. It shall be. Further, as shown in FIG. 38 (A), the chemical container 10 containing only "8.00 ml" of "5-FU injection 1000 mg" and the chemical container 10 containing only "3.50 ml" are in front. It is assumed that it is placed on the description shelf 33.

Then, as shown in FIG. 38 (B), "20 ml" of "5-FU injection 1000 mg" was stored corresponding to the three preparation data in which the tray 101 was already loaded in the storage unit 700. The chemical container 10, the chemical container 10 containing "20 ml" of "5-FU injection 1000 mg", and the chemical container 10 containing "20 ml" of "5-FU injection 1000 mg" are the storage unit 700. It is assumed that it is loaded inside. As shown in FIG. 38 (B), "15 ml", "20 ml" and "8 ml" of chemicals are used in the three preparation data, respectively. In this case, the remaining amount of the drug placed on the storage shelf 33 described above at the time when the loading start operation is performed for the target preparation data is "8.00 ml" + "" based on the remaining drug information. It is calculated as "11.50 ml" by "3.50 ml". Further, the chemicals loaded in the mixed injection device 1 in addition to other preparation data corresponding to one or a plurality of other mixed injection processes executed until the mixed injection process based on the target preparation data is executed. The amount of is calculated as "60 ml" by "20 ml" + "20 ml" + "20 ml" based on the corresponding information D31. Further, the total amount of the chemicals used in one or more other mixed injection processes performed before the mixed injection process based on the subject preparation data is "15 ml" + "20 ml" + "8 ml". Is calculated as "43 ml". Therefore, the residual liquid amount at the time of executing the mixed injection treatment based on the target preparation data becomes "28.50 ml" by "11.50 ml" + "60 ml"-"43 ml".

Further, when the execution time of the mixed injection process based on the target preparation data is reserved, the first control unit 400 calculates the remaining drug amount by excluding the remaining drug whose expiration date has expired in the execution time. do. For example, when the execution time of the mixed injection process based on the target preparation data is "2013/2/15 14:00", it occurs in the mixed injection process of the preparation data Rp11 among the remaining drug information shown in FIG. 38 (A). The residual drug amount is excluded from the remaining drug, and the residual liquid amount at the time of executing the mixed injection treatment based on the target preparation data is "20.5 ml" by "3.5 ml" + "60 ml"-"43 ml". Become. Similarly, for the residual drug generated in the mixed injection process executed after the time when the loading start operation is performed for the target preparation data, the expiration date of the residual drug generated in the mixed injection process after the execution of the mixed injection process is performed. May be excluded from the calculation of the residual liquid amount at the time of execution of the mixed injection process based on the target preparation data, if it elapses before the mixed injection process of the target preparation data is started.

Further, FIG. 38 (C) is a diagram showing another example of the corresponding information D31. The correspondence information D31 shown in FIG. 38 (C) is different from the correspondence information D31 shown in FIG. 38 (B) in that the chemical container 10 is not loaded in the preparation data “Rp23”. Therefore, in the storage unit 700, "20 ml" of "5-FU injection 1000 mg" is stored in the storage unit 700, corresponding to the three preparation data in which the tray 101 is already loaded in the storage unit 700. 10 and the drug container 10 containing "20 ml" of "5-FU injection 1000 mg" are loaded. In this case, the above-mentioned loaded in the mixed-injection apparatus 1 with other preparation data corresponding to one or a plurality of other mixed-injection processes executed until the mixed-injection process based on the target preparation data is executed. The amount of the chemical is calculated as "40 ml" by "20 ml" + "20 ml" based on the corresponding information D31. The amount of residual liquid at the time of executing the mixed injection treatment based on the target preparation data is "8.50 ml" by "11.50 ml" + "40 ml"-"43 ml".

Further, the operation key K11 and the operation key K12 are operation units for accepting selection of whether or not to use the residual liquid for the medicine contained as a prescription drug in the preparation data on the available residual liquid guidance screen F1. Is. The first control unit 400 determines that when the operation key K11 is operated, the residual liquid of the chemical corresponding to the chemical identification information is used, and when the operation key K12 is operated, the chemical identification Judge that the residual liquid of the chemical corresponding to the information is not used. Then, when it is selected to use the chemicals already existing in the mixed injection device 1, the first control unit 400 omits reading the identification information in the step S25 and proceeds to the process in step S26. In this case, the first control unit 400 stores the information that the chemical container 10 is not placed on the tray 101 corresponding to the preparation data in the corresponding information D31. The first control unit 400 has already entered the mixed injection device 1 without determining whether or not the chemical used in the mixed injection process based on the preparation data to be processed exists in the mixed injection device 1. It may be possible to accept an operation for selecting whether or not to use an existing chemical. Further, in the present embodiment, the configuration in which the residual drug after the mixed injection process based on other preparation data can be used in the mixed injection process based on the prepared data to be treated will be described, but the residual drug cannot be used. , The configuration may be such that only the chemicals already loaded in the mixed injection device 1 can be used in association with other preparation data.

<Step S26>
In step S26, the first control unit 400 causes the display 203 to display a message, an image, or the like for guiding the arrangement of the chemical container 10 on the tray 101. As a result, the user can easily arrange the chemical container 10 at a predetermined position in the tray 101. If a plurality of the chemical containers 10 are required, the steps S25 to S26 are repeatedly executed.

<Step S27>
In step S27, the first control unit 400 causes the display 203 to display a message, an image, or the like for guiding the arrangement of the syringe 11 on the tray 101. This allows the user to easily place the syringe 11 in a predetermined position within the tray 101. If a plurality of the syringes 11 are required, the step S27 is repeatedly executed.

<Step S28>
When all the guidance of the equipment necessary for the mixed injection process based on the preparation data is completed, in the following step S28, the first control unit 400 displays that the preparation for loading of the preparation data is completed, and also displays that the preparation for loading is completed. Display the operation keys for accepting the confirmation operation to that effect.

<Step S29>
In step S29, the first control unit 400 determines the presence or absence of the confirmation operation, and if the confirmation operation is performed (S29: Yes), the process is shifted to step S30, and the confirmation operation is performed. Until (S29: No), the process is made to wait in step S29.

<Step S30>
In step S30, the first control unit 400 opens the shutter 712 of the accommodation unit 700. Specifically, the first control unit 400 transmits an opening instruction of the shutter 712 to the second control unit 500. As a result, the second control unit 500 controls the accommodation unit 700 to open the shutter 712.

In addition, before opening the shutter 712, the second control unit 500 has the moving casing so that the unused tray accommodating unit 811 is arranged at the first moving position based on the corresponding information D31. Control the position of the body 810. Specifically, it is determined that the tray accommodating portion 811 that is not stored in the corresponding information D31 as the tray accommodating portion 811 corresponding to the tray 101 is unused. The second control unit 500 updates the corresponding information D31 when the tray 101 is loaded into the tray accommodating unit 811 and when the tray 101 is ejected from the tray accommodating unit 811.

For example, the second control unit 500 controls the accommodating unit 700 so that the unused tray accommodating unit 811 is arranged at the first moving position while the accommodating unit 700 is on standby (during non-operation). It is conceivable to do. Further, the second control unit 500 may move the moving housing 810 to arrange the unused tray accommodating unit 811 at the first moving position after receiving the opening instruction in step S30. good. When there are a plurality of unused tray accommodating units 811 in the second control unit 500, the moving housing required to move to the first moving position among the plurality of tray accommodating units 811. It is conceivable to select the tray accommodating portion 811 having the smallest movement amount of the 810 and move it to the first movement position.

<Step S31>
Then, in step S31, when the tray 101 is accommodated in the tray accommodating unit 811 of the accommodating unit 700, the second control unit 500 associates the identification information of the tray 101 with the tray accommodating unit 811. To execute. Specifically, the second control unit 500 updates the correspondence information D31 stored in the data storage unit 504 based on the correspondence between the identification information of the tray 101 and the tray accommodating unit 811. Thereby, the second control unit 500 can recognize the tray storage unit 811 of the storage destination of each of the tray 101 based on the corresponding information D31. Whether or not the tray 101 is accommodated in the tray accommodating portion 811 is detected by an optical sensor (not shown) provided in the tray accommodating portion 811 or the like.

<Step S32>
Next, in step S32, the second control unit 500 controls the storage unit 700 to perform a confirmation operation for confirming the correspondence between the tray 101 housed in the tray storage unit 811 and the preparation data. Run. This prevents the erroneous tray 101 from being accommodated in the tray accommodating portion 811.

Specifically, the second control unit 500 has the moving housing 810 so that the tray accommodating unit 811 determined in step S31 to accommodate the tray 101 is arranged at the second moving position. Move down. After that, the second control unit 500 discharges the tray 101 housed in the tray storage unit 811 to the first transport unit 910 of the tray transport unit 900, and is provided in the first transport unit 910. The IC reader 930 reads the identification information of the tray 101 from the tag 101b of the tray 101. Then, the second control unit 500 collates the identification information of the tray 101 read by the IC reader 930 with the identification information of the tray 101 corresponding to the preparation data received from the first control unit 400. .. Here, if the collation results are in agreement, the second control unit 500 returns the tray 101 to the tray accommodating unit 811, completes a series of the loading preparation processes, and returns the process to the step S21. On the other hand, when the collation results do not match, the second control unit 500 notifies the display 203 or the like of an error via the first control unit 400 and discharges the tray 101 toward the tray discharge port 206. do. As a result, the user can take out the tray 101 from the tray discharge port 206.

[Mixed injection start processing]
Subsequently, an example of the mixed injection start processing will be described with reference to FIG. 26.

<Step S41>
In step S41, the second control unit 500 determines whether or not the execution start timing of the mixed injection process has arrived. Specifically, the second control unit 500 determines that the execution start timing of the mixed injection process has arrived when the execution start request is received from the first control unit 400. Then, when it is determined that the execution start timing has arrived (S41: Yes), the process proceeds to step S411, and if the execution start timing has not arrived (S41: No), the process proceeds to step S42.

Specifically, the first control unit 400 performs the preparation data when the user performs the selection operation of the preparation data and the immediate start operation of the mixed injection process based on the preparation data by using the operation unit 405. The execution start request of the mixed injection process is transmitted to the second control unit 500. Further, when the execution start timing of the mixed injection process based on the preparation data is reserved by the reserved mixed injection operation, the first control unit 400 describes the preparation data when the execution start timing arrives. The execution start request of the mixed injection process is transmitted to the second control unit 500.

The execution start request includes, for example, an execution procedure of the mixed injection process based on the preparation data. Further, the execution procedure of the mixed injection process based on the preparation data is transmitted in advance from the first control unit 400 to the second control unit 500 and stored in the data storage unit 504, and the execution start request is described above. It may also include identification information for the preparation data.

<Step S42>
In step S42, the second control unit 500 determines whether or not the preparation data reserved by the first control unit 400 includes preparation data to be subject to the pre-stirring process for executing the stirring step in advance. to decide. Specifically, the drug master stores a pre-stirring target flag indicating whether or not the drug is the target of the pre-stirring process in association with each drug. Then, when the preparation data includes a chemical set as a target of the pre-stirring process by the pre-stirring target flag, the second control unit 500 is subject to the pre-stirring process. Judge that. Further, whether or not the second control unit 500 is the target of the pre-stirring process according to the combination of the chemical in the chemical container 10 and the infusion solution in the infusion bag 12 that are agitated in the stirring step. May be judged. In the second control unit 500, when a user operation for selecting an arbitrary preparation data as a target of the pre-stirring process has been performed in advance, the selected preparation data is the above-mentioned thing. It is also conceivable to determine that it is the target of the pre-stirring process. Then, when it is determined that the target of the pre-stirring process exists (S42: Yes), the process proceeds to step S43, and when it is determined that the target of the pre-stirring process does not exist (S42: No). ), The process is returned to step S41.

<Step S43>
In step S43, the second control unit 500 determines whether or not the pre-stirring process is feasible. For example, the second control unit 500 may determine whether or not the mixed injection process is being executed, and determine that the pre-stirring process can be executed when the mixed injection process is not executed. Conceivable. Further, the second control unit 500 may determine that the pre-stirring process can be executed at a specific time zone such as a preset nighttime or midnight. The index for determining whether or not the pre-stirring process is feasible is not limited to that described here. Then, when it is determined that the pre-stirring process is feasible (S43: Yes), the process proceeds to step S44, and when it is determined that the pre-stirring process is not feasible (S43: No). ), The process is returned to step S41. When the second control unit 500 performs a user operation for selecting the preparation data and starting the pre-stirring process, the pre-stirring process for the prepared data is executed. May be good.

Further, in step S43, the condition is that the second control unit 500 is equal to or longer than a predetermined lower limit required time for the stirring step associated with the drug in the drug container 10 in the drug master. It is also conceivable to determine that the pre-stirring process is to be performed. That is, when the required time of the stirring step is less than the lower limit required time, it is excluded from the target of the pre-stirring process. As a result, the pre-stirring process is executed only when the stirring step takes a long time, and it is suppressed that the pre-stirring process is unnecessarily executed. The second control unit 500 can arbitrarily set the lower limit required time according to the user operation. On the other hand, the second control unit 500 performs the pre-stirring on the condition that the required time of the stirring step associated with the drug in the drug container 10 in the drug master is less than a predetermined upper limit required time. It may be determined that the process will be executed. That is, when the required time of the stirring step is equal to or longer than the upper limit required time, it may be excluded from the target of the pre-stirring process. In this case, the pre-stirring process is executed only when the stirring step does not require a long time, and due to the pre-stirring process, the mixed injection process based on other preparation data and the like can be performed. Delays are suppressed. The second control unit 500 can arbitrarily set the upper limit required time according to the user operation.

In the hospital where the mixed injection device 1 is installed, it is conceivable that there is a busy period in which the mixed injection device 1 is frequently used at a specific time zone, a specific day of the week, a specific time, or the like. Therefore, in the mixed injection device 1, when the second control unit 500 determines whether or not the pre-stirring process is feasible in step S43 of the mixed injection start process, for example, in advance such as during the busy season. If the set timing condition is satisfied, it may be determined that the pre-stirring process is not feasible. That is, the second control unit 500 determines that the pre-stirring process cannot be executed if the timing condition is satisfied even when the mixed injection process is not being executed. This reduces the possibility that the pre-stirring process will be executed during the busy season and the start of the mixed injection process will be delayed.

<Step S44>
In step S44, the second control unit 500 controls the mixed injection processing unit 300 and the accommodation unit 700 to execute the pre-stirring process. When a plurality of the preparation data to be the target of the pre-stirring process are reserved, the preparation data to be processed are sequentially selected in the steps S41 to S44 and the pre-stirring process is executed. To.

The order of the preparation data selected as the processing target of the pre-stirring process is an order based on a time element such as the scheduled completion time or the execution start timing set in advance corresponding to the preparation data. Not exclusively. For example, it is considered as another embodiment that the preparation data is selected in the order of reception from the higher system 6, or the preparation data is randomly selected. In addition, the preparation data including the preset chemicals having a long time required for the stirring step are preferentially selected, or the preparation data using the same chemicals or infusion solution are continuously selected. It is possible that the order will be decided. Further, it is also conceivable that the drug master stores an index value indicating the ease of coagulation after the execution of the stirring step, and the preparation data is selected in order from the drug that is difficult to coagulate based on the index value. Be done.

Here, a specific processing example of the pre-stirring treatment will be described.

First, the second control unit 500 controls the storage unit 700 and injects the tray 101 associated with the preparation data selected as a processing target from the tray storage unit 811 of the storage unit 700. It is automatically transported to the tray transport unit 110 of the processing unit 300. The second control unit 500 identifies the tray storage unit 811 in which the tray 101 corresponding to the preparation data is housed, based on the correspondence information D31.

After that, the second control unit 500 controls the first robot arm 21, sets the chemical container 10 placed on the tray 101 in the stirring device 32, and uses the stirring device 32 to set the chemical container 10 in the stirring device 32. The stirring step of stirring the chemicals in the container is performed.

Specifically, when the tray 101 is supplied to the tray transport unit 110, the second control unit 500 reads the identification information of the tray 101 from the IC tag 101b of the tray 101 by the IC reader 101c. Then, the second control unit 500 opens the shutter 111 when the identification information of the tray 101 matches the identification information previously associated with the preparation data of the mixed injection process. After that, the second control unit 500 raises the equipment mounting unit 102 of the tray 101 by the tray elevating unit 112 of the tray transport unit 110 to expose it to the mixed injection processing chamber 104.

Next, the second control unit 500 photographs the equipment mounting unit 102 with the tray confirmation camera 41. Then, the second control unit 500 determines the position of the equipment such as the medicine container 10 and the syringe 11 mounted on the equipment mounting unit 102 by the image recognition process based on the image taken by the tray confirmation camera 41. Know the orientation. In particular, the second control unit 500 photographs the equipment mounting unit 102 with the tray confirmation camera 41 each time the medicine container 10 or the syringe 11 is taken out from the equipment mounting unit 102, and from the captured image. The position and orientation of the latest drug container 10 and the syringe 11 are grasped.

Subsequently, the second control unit 500 places the syringe 11 mounted on the equipment mounting unit 102 exposed in the mixed injection processing chamber 104 by the first robot arm 21 on the above-mentioned storage rack 33. Temporarily place. Further, the second control unit 500 sets the chemical container 10 mounted on the equipment mounting portion 102 in the chemical reading unit 34 by the first robot arm 21. Then, the second control unit 500 reads information such as the type of the chemical contained in the chemical container 10 by the chemical reading unit 34.

Next, when the second control unit 500 takes out all the equipment on the equipment mounting unit 102, the tray elevating unit 112 of the tray transport unit 110 lowers the equipment mounting unit 102 to lower the tray. Return to 101. The second control unit 500 confirms whether or not all the equipment on the equipment mounting unit 102 has been taken out by image recognition processing based on the captured image by the tray confirmation camera 41.

After that, the second control unit 500 closes the shutter 111 and causes the tray transport unit 110 to transport the tray 101 to the tray transport end portion 110a. Next, the second control unit 500 sets the mixed injection port of the infusion bag 12 held by the infusion bag holding unit 103 of the tray 101 by the bag elevating unit 113 of the tray transport unit 110 into the mixed injection processing chamber. It is located at the mixed injection communication port 37 formed in 104.

Then, the second control unit 500 moves the chemical container 10 set in the chemical reading unit 34 to the above-mentioned storage shelf 33 by the second robot arm 22. On the other hand, in parallel with this movement process, the second control unit 500 attaches / detaches the injection needle 11c of the syringe 11 mounted on the equipment mounting unit 102 by the first robot arm 21. Set in the device 43.

Next, the second control unit 500 takes out the syringe 11 from the above-mentioned storage rack 33 by the first robot arm 21 and sets it in the second robot arm 22. Subsequently, the second control unit 500 moves the syringe 11 to the injection needle attachment / detachment device 43 by the second robot arm 22 to set the injection needle 11c in the syringe 11. After that, the second control unit 500 moves the syringe 11 to the needle bending detection unit 36 by the second robot arm 22, and detects the presence or absence of bending of the injection needle 11c.

Subsequently, the second control unit 500 pierces the injection needle 11c of the syringe 11 into the rubber stopper of the mixed injection port of the infusion bag 12 conveyed to the tray transfer end portion 110a by the second robot arm 22. Then, the infusion solution in the dissolved amount shown in the preparation data is sucked from the infusion solution bag 12. On the other hand, the second control unit 500 takes out the chemical container 10 mounted on the above-mentioned storage shelf 33 by the first robot arm 21.

Then, the second control unit 500 brings the medicine container 10 and the syringe 11 closer to each other by the first robot arm 21 and the second robot arm 22, and the injection needle 11c of the syringe 11 is said. Puncture into the drug container 10. After that, the second control unit 500 injects the infusion solution in the syringe 11 into the medicine container 10 by operating the plunger 11b by the second robot arm 22.

In the mixed injection processing chamber 104, a dedicated container containing the infusion solution used in the pre-stirring treatment is housed, and in the pre-stirring treatment, the infusion solution in the dedicated container is transferred to the chemical container 10. It may be infused. It is also conceivable that a plastic ampoule containing an infusion solution used in the pre-stirring process is set in the tray 101 in advance, and the infusion solution in the plastic ampoule is used in the pre-stirring process.

Next, the second control unit 500 sets the chemical container 10 into which the infusion solution has been injected in the stirring device 32 by the first robot arm 21. As a result, in the stirring device 32, a stirring step in which the medicine and the infusion solution in the medicine container 10 are stirred is executed. When the stirring step by the stirring device 32 is completed, the second control unit 500 takes out the chemical container 10 from the stirring device 32 by the first robot arm 21.

Then, the second control unit 500 controls the first robot arm 21, moves the chemical container 10 to the above-mentioned storage shelf 33 in the mixed injection processing unit 300, and places the medicine container 10 on the storage shelf 33, and also uses the preparation data. The data storage unit 504 stores correspondence information (an example of the second correspondence information) indicating the correspondence relationship with the medicine container 10 placed at each position on the above-mentioned storage shelf 33. Here, the first control unit 400 when executing the storage processing is an example of the second storage processing unit. For example, in the corresponding information, the chemical container 10 is managed so as to be identifiable with container identification information such as an ID set in advance for each placement position on the above-mentioned storage shelf 33. Further, the correspondence relationship between the medicine container 10 placed at each position on the above-mentioned storage shelf 33 and the identification information of the preparation data may be stored in the correspondence information D31. The above-mentioned storage shelf 33 is an example of a container mounting portion and a syringe mounting portion on which one or more of the drug containers 10 and one or more of the syringes 11 can be placed.

Further, the second control unit 500 controls the first robot arm 21 and the second robot arm 22, and the syringe 11 is moved to the previously described storage shelf 33 in the mixed injection processing unit 300 and placed. At the same time, the position of the syringe 11 on the previously described storage shelf 33 is stored in the data storage unit 504 in association with the identification information of the preparation data. Thereby, the second control unit 500 can specify the positions of the medicine container 10 and the syringe 11 used in the mixed injection process based on the preparation data. The syringe 11 used in the pre-stirring process may be provided in advance on the above-mentioned storage rack 33 for each type of infusion solution as a dedicated syringe used in the pre-stirring process. ..

On the other hand, the second control unit 500 controls the tray transport unit 110 to return the infusion bag 12 to the tray 101, and moves the tray 101 from the tray transport end portion 110a to the tray transport start unit 110b. Let me. After that, the second control unit 500 controls the belt conveyor (not shown) provided at the tray transfer start unit 110b of the tray transfer unit 110, and the storage unit 700 side via the tray loading port 114. Is supplied with the tray 101. Then, the second control unit 500 controls the storage unit 700 and stores the tray 101 in the tray storage unit 811. The tray accommodating portion 811 used at this time is associated with the identification information of the tray 101 in the corresponding information D31. Also in this case, the second control unit 500 uses the IC reader 101c and the IC reader 930 to collate the correspondence between the identification information of the tray 101 and the preparation data. As described above, in the pre-stirring process, the tray 101 moves from the accommodating unit 700 to the mixed injection processing unit 300 side, but the tray 101 is not carried into the mixed injection processing chamber 104 and is not carried into the accommodating unit. It will be returned to 700. Therefore, the contamination of the tray 101 in the pre-stirring process is prevented, and the contamination of the tray accommodating section 811 on which the tray 101 returned from the mixed injection processing section 300 is placed is prevented.

In the mixed injection device 1, the dedicated syringe 11 and the plastic ampoule used in the pre-stirring process can be placed on the above-mentioned storage shelf 33, and the dedicated syringe 11 and the plastic ampoule are used. The pre-stirring process may be performed. For example, in the mixed injection device 1, the second control unit 500 performs a replenishment request operation for the dedicated syringe 11 or the plastic ampoule used in the pre-stirring process, and is in front of the mixed injection processing unit 300. When a tray on which the dedicated syringe 11 or the plastic ampoule used in the pre-stirring process is placed is loaded, the second robot arm 22 is controlled to move the syringe 11 or the plastic ampoule in front. Set it on the description shelf 33. Further, the dedicated syringe 11 or the plastic ampoule used in the pre-stirring process may be placed in a predetermined position on the storage shelf 33 described above by the user.

By the way, when there are a plurality of the preparation data having the same combination and concentration of the chemical and the solution to be stirred in the pre-stirring treatment in the preparation data currently reserved, the preparation data thereof. It is conceivable that the pre-stirring process will be performed on only a smaller number of the prepared data than the total number. This makes it possible to use the chemical container 10 after the pre-stirring treatment for the mixed injection treatment corresponding to any of the plurality of preparation data. Specifically, it is conceivable that the second control unit 500 reallocates the chemical container 10 corresponding to the preparation data as the chemical container 10 used in the other preparation data. As a result, the waste of the chemical container 10 when the mixed injection treatment based on any of the preparation data is canceled is suppressed as compared with the case where the pre-stirring treatment is performed for all the preparation data. .. It is conceivable that the second control unit 500 may require a preset confirmation operation by the user when reallocating the chemical container 10 and the preparation data. For example, in the second control unit 500, at the start of the mixed injection process based on the preparation data, the drug container 10 having the same combination and concentration of the drug and the infusion solution contained in the preparation data is placed in the above-mentioned placement unit 33. If it has already been placed, an operation screen for selecting whether or not to use the chemical container 10 in the mixed injection process based on the preparation data is displayed. Then, when the operation to use the chemical container 10 is performed on the operation screen, the second control unit 500 uses the chemical container 10 in the mixed injection process.

<Step S411>
On the other hand, when the execution start timing of the mixed injection process has arrived (S41: Yes), the second control unit 500 includes the mixed injection process based on the preparation data in the subsequent step S411. Execute mixed injection control processing. As described above, the second control unit 500 executes the mixed injection process when the immediate start operation is performed by the user or when the reserved execution start timing arrives. That is, the execution start timing of the mixed injection process includes the time when the immediate start operation is performed by the user and the time when the reserved execution start timing arrives. The details of the mixed injection control process will be described later.

By the way, in the mixed injection management device 100, whether or not the chemical remains in the chemical container 10 based on the weight of the chemical container 10 after the mixed injection treatment is executed by the second control unit 500 in the step S16. It is possible to judge whether or not. Specifically, after the mixed injection process is completed, the second control unit 500 places the chemical container 10 on the weigh scale 35 using the first robot arm 21 or the second robot arm 22, and the chemicals. Weigh the container 10. Then, the second control unit 500 calculates the difference between the empty weight of the drug container 10 stored in the drug master and the weight of the drug container 10 after the mixed injection process is executed. It is possible to detect the remaining amount of the chemical in the chemical container 10 after the mixed injection treatment is executed. Here, the second control unit 500 when executing the detection process is an example of the remaining amount detecting means. As a result, the first control unit 400 preferentially displays the preparation data in which the residual drug can be used based on the remaining amount of the residual drug actually remaining in the drug container 10 after the mixed injection treatment. It is possible to do. The method for detecting the remaining amount of the chemical in the chemical container 10 is not limited to this, for example, the chemical container 10 is imaged using a camera, and the chemical in the chemical container 10 is imaged based on the captured image. It is also possible to detect the remaining amount. In addition, the amount of chemicals (chemicals) in the syringe 11 acquired by the second control unit 500 based on the weight of the syringe 11 measured by the scale 35 or the image captured by the syringe confirmation camera 42. It is also possible to detect the remaining amount of the chemical in the chemical container 10 by calculating the difference between the amount taken out from the container 10) and the predetermined amount of the chemical container 10.

[Mixed injection control processing]
Subsequently, with reference to FIG. 27, an example of the procedure of the mixed injection control process executed by the second control unit 500 in the step S411 of the mixed injection start process will be described.

<Step S51>
In step S51, the second control unit 500 determines whether or not it is possible to use the residual drug remaining in the mixed injection process executed in the past in the mixed injection process for the prepared data. do. Specifically, the second control unit 500 includes a drug of the same type as the residual drug in the prescription drug based on the residual drug information stored in the data storage unit 404 by the first control unit 400. It is determined whether or not the dispensing data has been selected as the target of the mixed injection process. Further, the second control unit 500 determines whether or not the content of the remaining drug information satisfies a preset usage condition. The usage conditions are, for example, that the expiration date of the remaining drug stored in the remaining drug information has not passed, or that a predetermined time has not passed since the opening date and time of the remaining drug. As a result, for example, it is possible to set that the expiration date of the remaining drug has not passed as the usage condition, and to use only the remaining drug whose expiration date has not passed.

That is, the second control unit 500 uses conditions in which the dispensing data containing a drug of the same type as the residual drug in the prescription drug is selected as the target of the mixed injection process, and the content of the residual drug information is preset. If the above conditions are met, it is determined that the residual drug can be used. This makes it possible to automatically eliminate the use of the residual drug when the conditions of use are not satisfied. The first control unit 400 determines whether or not the remaining medicine can be used, and the second control unit 500 determines whether or not the remaining medicine can be used from the first control unit 400. The indicated control signal may be received.

Further, the usage conditions are the remaining amount of the remaining drug in the drug container 10 calculated based on the preparation data and the predetermined amount of the drug container 10, and the second control unit 500 after the mixed injection process is executed. It is also possible to include that the difference from the remaining amount of the remaining medicine in the medicine container 10 detected by the above is within a preset range. As a result, there is a difference between the remaining amount of the remaining medicine actually remaining in the medicine container 10 and the calculated value (predicted value) of the remaining amount based on the preparation data and the predetermined amount of the medicine container 10. It is possible to prevent the use of the residual drug when the predetermined allowable amount is exceeded. For example, when the medicine is sucked from the medicine container 10 by the syringe 11, the medicine leaks, and the remaining amount of the remaining medicine actually remaining in the medicine container 10 after the mixed injection treatment is less than the calculated value. In this case, since it is possible to determine that fact before the start of the next mixed injection process, it is possible to prevent an error in which a shortage of chemicals is found after the start of the mixed injection process. The conditions of use are the remaining amount of the remaining drug in the drug container 10 calculated based on the preparation data and the predetermined amount of the drug container 10, and the syringe confirmation camera during the execution of the mixed injection process. The difference between the amount of the drug sucked into the syringe 11 imaged by 42 and the remaining amount of the remaining drug in the drug container 10 calculated based on the predetermined amount of the drug container 10 is preset. It may include being within the range.

Here, when the second control unit 500 determines that the residual drug can be used (Yes side of S51), it shifts the process to step S53 and determines that the residual drug cannot be used (S51). No side), the process is shifted to step S52.

<Step S52>
In step S52, the second control unit 500 determines whether or not the mixed injection process based on the preparation data to be processed this time is executed by the immediate start operation. Then, when it is determined that the execution is performed by the immediate start operation (S52: Yes), the process proceeds to step S521, and it is determined that the processing is not executed by the immediate start operation (S52). : No), the process proceeds to step S523.

<Step S521>
In step S521, the second control unit 500 uses the chemicals in the chemical container 10 already loaded in the mixed injection device 1 (hereinafter referred to as “loaded chemicals”) in the mixed injection processing for the preparation data. To determine if is available. Specifically, in the second control unit 500, based on the corresponding information D31 stored in the data storage unit 405, the dispensing data containing a drug of the same type as the loaded drug in the prescription drug is subjected to the mixed injection process. Judge whether or not it was selected as the target of. Here, if it is determined that the loaded chemicals can be used (S521: Yes), the process proceeds to step S522, and if it is determined that the loaded chemicals cannot be used (S521: No), The process proceeds to step S523.

Specifically, the second control unit 500 loads the medicine container 10 corresponding to other preparation data different from the preparation data to be processed when the medicine container 10 is housed in the tray 101 in the storage unit 700. It is conceivable to judge that the finished chemicals can be used. Further, in the second control unit 500, the chemical container 10 corresponding to other preparation data different from the preparation data to be processed is already taken into the mixed injection processing chamber 104 from the tray 101 in the storage unit 700. When it is placed on the above-mentioned storage shelf 33, it may be determined that the loaded chemicals can be used. Further, in the second control unit 500, the chemical container 10 corresponding to other preparation data different from the preparation data to be processed is already mixed-injected from the tray 101 in the storage unit 700 in the pre-stirring process. When it is taken into the chamber 104 and placed on the above-mentioned storage shelf 33, it is conceivable to determine that the loaded chemicals can be used.

The second control unit 500 can accept the user setting of whether or not the loaded chemical is used for each of the prepared data, and the user setting is set to not use the loaded chemical. If so, it may be determined in step S521 that the loaded chemicals are not usable.

<Step S522>
In step S522, the second control unit 500 is housed in the storage unit 700 corresponding to preparation data (an example of the second preparation data) different from the preparation data to be processed (an example of the first preparation data). Using the chemicals in the chemical container 10, the mixed injection treatment based on the preparation data to be treated is executed. That is, in the mixed injection process based on a certain preparation data by the mixed injection processing unit 300, the second control unit 500 is loaded into the mixed injection device 1 in advance in association with other preparation data different from the preparation data. It is possible to use the chemicals in the chemical container 10.

Specifically, when the second control unit 500 executes step S522, the chemical container 10 corresponding to other preparation data different from the preparation data to be processed is housed in the tray 101 in the storage unit 700. If so, the storage unit 700 is controlled to supply the tray 101 from the storage unit 700 to the mixed injection processing chamber 104. Then, the second control unit 500 controls the first robot arm 21 to place the chemical container 10 housed in the tray 101 on the loading shelf 33, and places the tray 101 on the storage unit 700. Return to. After that, the tray 101 corresponding to the preparation data to be processed is supplied from the storage unit 700 to the mixed injection processing chamber 104, and the chemical container 10 corresponding to the other preparation data placed on the storage shelf 33 described above is provided. The mixed injection process is performed using the above. As a result, in the mixed injection device 1, for example, even if it takes time to prepare the chemicals contained in the preparation data to be processed, the chemicals already existing in the mixed injection device 1 are used based on the preparation data. It is possible to execute the mixed injection process.

Further, in the second control unit 500, the chemical container 10 corresponding to other preparation data different from the preparation data to be processed is already taken into the mixed injection processing chamber 104 from the tray 101 in the storage unit 700. When the product is placed on the storage shelf 33 described above, the mixed injection process is performed using the chemical container 10 placed on the storage shelf 33. Similarly, in the second control unit 500, the chemical container 10 corresponding to other preparation data different from the preparation data to be processed is already mixed-injected from the tray 101 in the storage unit 700 in the pre-stirring process. When it is taken into the chamber 104 and placed on the above-mentioned storage shelf 33, the mixed injection process is executed using the chemical container 10 placed on the storage shelf 33. However, the second control unit 500 has the concentration of the chemical in the chemical container 10 after dissolution in the preparation data to be processed, and the mixed injection processing chamber from the tray 101 in the storage unit 700 already in the pre-stirring treatment. The chemicals taken into the 104 and placed on the storage shelf 33 described above are used on condition that the concentration of the chemicals is the same as that of the chemicals placed on the storage shelf 33. As a result, the mixed injection device 1 can quickly execute the mixed injection process based on the prepared data even before the pre-stirring process is executed for the prepared data to be processed.

By the way, in step S522, the chemicals in the chemical container 10 contained in the storage unit 700 corresponding to other preparation data different from the preparation data to be processed are used to obtain the preparation data to be processed. When the mixed injection process based on the above is executed, the chemical container 10 will be insufficient when the mixed injection process based on the other preparation data is executed. Therefore, when the chemical container 10 is placed on the tray 101 corresponding to the preparation data of the processing target, the second control unit 500 after the mixed injection processing based on the preparation data of the processing target is completed. The chemical container 10 is placed on the above-mentioned storage shelf 33 as the chemical container 10 used in the mixed injection treatment based on the other preparation data. Further, when the pre-stirring process is executed for the chemical container 10, the second control unit 500 receives the tray 101 corresponding to the preparation data after the mixed injection process based on the preparation data to be processed is completed. After performing the pre-stirring treatment on the chemical container 10 housed in the above-mentioned chemical container 10, the chemical container 10 is placed on the above-mentioned storage shelf 33.

In the second control unit 500, when the tray 101 corresponding to the preparation data to be processed is loaded into the mixed injection device 1, the chemical container 10 is not placed on the tray 101. After the mixed injection process based on the preparation data to be processed is completed, the user is notified by displaying a message or the like prompting the replenishment of the drug container 10 on the touch panel monitor 14. Further, the second control unit 500 places the chemical container 10 replenished by the user on the storage shelf 33 described above as a chemical container 10 used in the mixed injection process based on the other preparation data. When the chemical container 10 requires the pre-stirring treatment, the second control unit 500 replenishes the chemical container 10 by the user after the mixed injection treatment based on the preparation data to be processed is completed. After performing the pre-stirring process, the chemical container 10 is placed on the above-mentioned storage shelf 33.

Further, in the mixed injection device 1, even if the chemical container 10 corresponding to the other preparation data is not replenished after the completion of the mixed injection processing based on the preparation data to be processed, the mixed injection processing based on the other preparation data can be performed. If a chemical used in the mixed injection process is present in the mixed injection device 1 at the time of execution, the mixed injection process is executed using the chemical. That is, it is not necessary that all the chemicals corresponding to all the preparation data are loaded in the mixed injection device 1, and a smaller number of chemicals are loaded than the chemicals corresponding to all the preparation data. , The chemical can be effectively used in the mixed injection process based on each of the preparation data. Therefore, for example, waste of chemicals when the mixed injection process is canceled after the chemical container 10 used in the mixed injection process based on the preparation data input to the mixed injection device 1 is loaded into the mixed injection device 1 is suppressed. ..

When a smaller number of chemicals than the chemicals corresponding to all the preparation data are loaded, the mixed injection processing is carried out in the mixed injection apparatus 1 when the mixed injection processing based on the other preparation data is executed. The chemicals used in may not exist. Therefore, when the second control unit 500 executes the mixed injection process based on the preparation data to be processed, the touch panel monitor 14 is provided on the condition that the chemical used in the mixed injection process does not exist in the mixed injection device 1. Alternatively, it is conceivable to notify the user by displaying on the display unit of the display 203 or the like that the chemical container 10 corresponding to the chemical used in the mixed injection process is to be replenished. Then, the second control unit 500 executes the mixed injection process using the replenished chemical container 10.

Further, in step S522, the second control unit 500 may be able to switch whether or not to use the loaded chemicals in the mixed injection process for the preparation data according to the user's selection. For example, the second control unit 500 causes the user to display an operation screen for selecting whether or not to use the loaded chemicals on the touch panel monitor 14 or the display unit such as the display 203, and responds to the user operation. It is conceivable to switch the use or non-use of the chemical container 10.

In the present embodiment, the case where the chemical container 10 loaded in the mixed injection device 1 in association with one preparation data can be used in the mixed injection processing based on other preparation data has been described as an example. The diversion of such equipment is not limited to the chemical container 10. For example, the mixed injection control unit 100 of the chemical container 10, the syringe 11, and the infusion bag 12 placed as equipment in the tray 101 loaded in the mixed injection device 1 in association with one preparation data. It is also conceivable that one or more of them can be used in a mixed injection process based on other preparation data. In addition, when the syringe 11 or the infusion bag 12 is diverted instead of the medicine container 10, it may be treated in the same manner as the medicine container 10, so detailed description thereof will be omitted.

<Step S523>
In step S523, the second control unit 500 controls the mixed injection processing unit 300 based on the preparation data input from the first control unit 400 to transfer the medicine container 10 to the infusion bag 12. The usual mixed injection process of injecting chemicals is performed.

Specifically, in step S523, the second control unit 500 controls the accommodation unit 700, and the tray 101 associated with the preparation data whose execution start timing has arrived is the tray 101 of the accommodation unit 700. It is automatically supplied from the tray accommodating unit 811 to the mixed injection processing unit 300. Then, in the mixed injection process, the second control unit 500 sucks the medicine shown in the preparation data from one or more of the medicine containers 10 placed on the tray 101 by the syringe 11, and the syringe. Inject from 11 into the infusion bag 12.

The second control unit 500 includes identification information of the tray 101 that is carried out from the tray accommodating unit 811 and read from the IC tag 101b of the tray 101 mounted on the first transport unit 910. It is conceivable to collate with the identification information of the tray 101 associated with the preparation data. Then, the second control unit 500 supplies the tray 101 to the mixed injection processing unit 300 when the collation results match, and notifies an error when the collation results do not match. The tray 101 is discharged toward the tray discharge port 206. This ensures the accuracy of the correspondence between the tray 101 and the preparation data.

When the preparation data is the preparation data in which the stirring step has already been executed by the pre-stirring treatment, the mixed injection is performed using the chemical container 10 after being stirred by the pre-stirring treatment. The process is carried out and the stirring step is omitted. Specifically, in the mixed injection process, the chemical container 10 that was the target of the pre-stirring process is not taken out from the tray 101, and is placed on the pre-described shelf 33 during the pre-stirring process. The chemical container 10 after the placed stirring step is used. Similarly, in the mixed injection process, the syringe 11 used in the pre-stirring process was not taken out from the tray 101, and was placed on the above-mentioned storage shelf 33 during the pre-stirring process. The syringe 11 is used. Then, the second control unit 500 omits the stirring step for the chemical container 10 in the mixed injection process using the chemical container 10 in which the stirring step is executed in the pre-stirring process and has already been stirred. do. As a result, the time required after the execution start timing of the mixed injection process is reached is shortened. The second control unit 500 executes the stirring step in the mixed injection process for the chemical container 10 stirred in the pre-stirring process as compared with the case where the pre-stirring process is not executed. It is also possible to shorten the time and execute.

By the way, in the mixed injection device 1, after the pre-stirring process is executed for a certain preparation data, if the mixed injection process for the prepared data is not continuously executed, the mixed injection process for the prepared data is performed. The mixed injection process or the pre-stirring process based on other preparation data may be executed until the execution start timing arrives. That is, in the mixed injection device 1, another step is performed between the stirring step performed by the pre-stirring processing unit for the prepared data and the injection step performed by the mixed injection processing unit for the prepared data. At least one of the stirring step and the injecting step for the prepared data may be performed. Therefore, as another embodiment, the execution start timing is such that at least one of the stirring step and the injection step corresponding to the other preparation data is executed after the execution of the stirring step corresponding to the preparation data. It may be the timing after that. For example, it is conceivable that the pre-stirring process is sequentially executed for the plurality of prepared data at night, and then the mixed injection process for the plurality of prepared data is executed the next morning or the like.

<Step S53>
On the other hand, in step S53, the second control unit 500 controls the mixed injection processing unit 300 based on the preparation data input from the first control unit 400, thereby using the residual drug to infuse the infusion solution. The exceptional mixed injection process of injecting a drug into the bag 12 is performed. Therefore, for example, when the chemical remains in the chemical container 10 after the mixed injection treatment, the chemical is effectively used and waste of the chemical is suppressed. In particular, in the mixed injection device 1, when the same drug as the drug corresponding to the preparation data to be processed already exists in the mixed injection device 1 as a residual drug, the residual drug is already contained in the storage unit 700. The mixed injection process is performed by being used in preference to other chemicals existing in the tray 101.

It should be noted that the first control unit 400 or the second control unit 500 is no longer necessary due to the use of the residual drug as compared with the case where the residual drug is not used in the mixed injection process based on the preparation data. It is conceivable that the number can be stored as a residual drug usage history and output to a display unit such as the display 203 or the touch panel monitor 14. Thereby, the user can grasp the efficiency of the residual drug utilization by referring to the residual drug utilization history.

<Step S54>
When the mixed injection process is completed, in step S54, the second control unit 500 determines whether or not the chemical remains in the chemical container 10. The determination process in step S54 may be the same process as step S16 executed by the first control unit 400, but indicates whether or not the residual drug is generated from the first control unit 400. A control signal may be received.

Here, when the second control unit 500 determines that the chemical remains (Yes side of S54), the process shifts to step S55, and determines that the chemical does not remain (No side of S54). The process shifts to step S541.

<Step S55>
When the chemical remains in the chemical container 10, in the subsequent step S55, the second control unit 500 stores the chemical in the chemical container 10 in the mixed injection processing chamber 104 in a state where the chemical can be reused. More specifically, the second control unit 500 controls the first robot arm 21 to place the chemical container 10 on the above-mentioned storage shelf 33 in a reusable state. Further, the second control unit 500 includes the name of the drug, the remaining amount of the drug in the drug container 10, the placement position of the drug container 10, the opening date and time of the drug container 10, and the inside of the drug container 10. Various information such as the expiration date of the remaining medicine is stored in the data storage unit 504.

<Step S541>
On the other hand, when no chemical remains in the chemical container 10, the second control unit 500 discards the chemical container 10 in the garbage storage chamber 13a by the first robot arm 21 in step S541. That is, when the chemicals in the chemical container 10 are not used up, the chemical container 10 is returned to the above-mentioned storage shelf 33, and when the chemicals in the chemical container 10 are used up, the chemical container 10 is discarded. ..

[Operation example of mixed injection device 1]
Here, FIG. 28 is a diagram for explaining an actual operation example when the mixed injection management process and the mixed injection control process are executed by the mixed injection control device 100. 28 (A) shows an example of preparation data, FIG. 28 (B) shows an example of residual drug information, and FIGS. 28 (C) to 28 (E) show an example of displaying a part of the prescription display unit D2. For convenience of explanation, the information shown in FIG. 28 omits information items that are less relevant to the present case.

Here, as shown in FIG. 28A, consider a case where the preparation data Rp1 to Rp4 are input to the first control unit 400 as selection candidates for the dispensing data to be the target of the mixed injection treatment. For example, in the preparation data Rp1, the specified amount of the ampoule 10A containing the drug to be prepared with the drug name "5-FU injection 1000 mg", the dispensed amount "15 ml", and the drug name "5-FU injection 1000 mg". Is shown to be "20 ml". Further, in the preparation data Rp2, the ampoule containing the drug having the drug name "Kiloside N (registered trademark) Note 1 g", the payout amount "50 ml", and the drug name "Kiloside N Note 1 g" is contained. The default amount of 10A is shown to be "50 ml". The first control unit 400 acquires default amounts corresponding to the drug names "5-FU injection 1000 mg", "kiloside N Note 1 g", etc. from the drug master stored in the data storage unit 404. You may. Further, the first control unit 400 may acquire the predetermined amount from the barcode of the chemical container 10 by the barcode reader 34b.

Then, when the preparation data Rp1 is selected as the target of the mixed injection process in the first control unit 400, the first control unit 400 calculates the difference (5 ml) between the payout amount and the predetermined amount. .. As a result, the first control unit 400 determines that the drug name "5-FU injection 1000 mg" remains "5 ml" in the ampoule 10A, and the remaining drug information (see FIG. 28 (B)). Is stored in the data storage unit 404. In the residual drug information shown in FIG. 28 (B), the drug having the drug name “5-FU injection 1000 mg” remains in the ampoule 10A by the remaining amount “5 ml”, and the opening date and time is “2013/02/15”. It is indicated that "11:00" and the expiration date is "13:00 on 2013/02/15".

Here, for convenience of explanation, a case where the prescription amount is equal to or less than the predetermined amount of the ampoule 10A and the ampoule 10A used is one will be described as an example. On the other hand, when the prescribed amount exceeds the predetermined amount of the ampoule 10A, a plurality of the ampoules 10A are used, and as a result, the drug remains in one ampoule 10A. For example, when the prescription amount of the preparation data Rp1 is "30 ml", two ampoules 10A are loaded in the tray 101. At this time, the first control unit 400 has "10 ml" of chemicals in the second ampoule 10A due to the difference between the total amount of "40 ml" of the two ampoules 10A and the prescribed amount of "30 ml". Judge that it remains.

Next, the first control unit 400 contains, as a prescription drug, a drug of the same type as the residual drug having the drug name "5-FU Injection 1000 mg" shown in the residual drug information among the preparation data Rp2 to Rp4. It is determined that the residual drug can be used in the mixed injection treatment for the preparation data Rp3 and Rp4.

Then, as shown in FIG. 28C, the first control unit 400 rearranges the preparation data Rp3 and Rp4 among the preparation data Rp2 to Rp4 to be higher than the preparation data Rp2, and the prescription selection screen. It is preferentially displayed on M1 (see FIG. 29). Further, as shown in FIG. 28C, the first control unit 400 prepares the preparation by displaying “◯” on the residual drug presence / absence display unit D21 (see FIG. 29) on the prescription selection screen M1. Data Rp3 and Rp4 indicate that the residual drug can be used. As a result, the user recognizes that the residual drug can be used by subjecting the preparation data Rp3 and Rp4 displayed higher on the prescription selection screen M1 to the next mixed injection process. be able to. As shown in FIG. 28C, for the preparation data Rp2 in which a drug of a type different from the residual drug is a prescription drug, “◯” is not displayed on the residual drug presence / absence display unit D21. It is indicated that the residual drug cannot be used.

For example, in the preparation data Rp3, the predetermined amount of the ampoule 10A containing the drug to be prepared with the drug name "5-FU injection 1000 mg", the dispensed amount "25 ml", and the drug name "5-FU injection 1000 mg". Is shown to be "20 ml". Then, in the mixed injection process for the preparation data Rp3, two ampoules 10A are required. However, if the drug "5-FU injection 1000 mg" remains "5 ml" as the residual drug and the residual drug can be used, one of the above-mentioned mixed injection treatments targeting the preparation data Rp3 Only the ampoule 10A needs to be newly loaded.

On the other hand, in the preparation data Rp4, the predetermined amount of the ampoule 10A containing the drug to be prepared with the drug name "5-FU injection 1000 mg", the dispensed amount "5 ml" and the drug name "5-FU injection 1000 mg". Is shown to be "20 ml". Then, in the mixed injection process for the preparation data Rp4, one ampoule 10A is required. However, if the drug "5-FU injection 1000 mg" remains "5 ml" as the residual drug and the residual drug can be used, the ampoule 10A is used in the mixed injection process for the preparation data Rp4. There is no need to load a new one. Therefore, another embodiment may be considered in which the first control unit 400 preferentially displays the preparation data, that is, the preparation data Rp4, for which the amount to be paid out is sufficient for the remaining amount of the remaining medicine.

By the way, as shown in FIG. 28D, the first control unit 400 only displays the preparation data Rp3 and Rp4 among the preparation data Rp2 to Rp4 in order to preferentially display the preparation data Rp3 and Rp4. Can be displayed on the prescription selection screen M1. Further, as shown in FIG. 28E, when the prescription date for the patient is preset for the preparation data Rp3 and Rp4, the first control unit 400 has the earlier prescription date, that is, the preparation. It is also conceivable to preferentially display the data Rp4 at the higher level.

When a plurality of types of drugs accompanied by a plurality of mixed injection treatments are present in one preparation data, the first control unit 400 determines the presence or absence of the residual drug in each of the mixed injection treatments, and at least the remaining drugs. It is conceivable to preferentially display the preparation data containing the same type of drug as a prescription drug. Further, when the first control unit 400 has a plurality of types of the residual drug, it is conceivable to display the preparation data having a large number of drugs of the same type as the residual drug contained as the prescription drug at the higher level.

[Other operation examples of mixed injection device 1]
Here, FIG. 29 is a diagram for explaining another actual operation example when the mixed injection management process and the mixed injection control process are executed by the mixed injection control device 100. 29 (A) shows an example of preparation data, FIG. 29 (B) shows an example of residual drug information, and FIG. 29 (C) shows an example of displaying a part of the prescription display unit D2. For convenience of explanation, the information shown in FIG. 29 omits information items that are less relevant to the present case.

Here, as shown in FIG. 29 (A), consider a case where the preparation data Rp11 to Rp15 are input to the first control unit 400 as selection candidates for the dispensing data to be the target of the mixed injection process. For example, in the preparation data Rp11, the drug name to be prepared is "Gemzar (registered trademark) injection 1 g", the dispensed amount is "25 ml", the solvent is "physiological saline 100 ml", and the solvent amount is "30 ml". That is, in the preparation data Rp11, the components of the mixed drug produced in the vial bottle 10B are the drug "Gemzar injection 1 g" and the solvent "physiological saline solution 100 ml". Similarly, in the preparation data Rp12, the drug name to be prepared is "mitomycin (registered trademark) injection 2 mg", the dispensed amount is "5 ml", the solvent is "physiological saline 100 ml", and the solvent amount is "5 ml". Further, in the preparation data Rp15, the name of the drug to be prepared is "1 g for injection of Gemzar", the amount to be dispensed is "25 ml", the solvent is "glucose injection 5% 100 ml", and the amount of solvent is "30 ml".

Then, when the preparation data Rp11 is selected as the target of the mixed injection process in the first control unit 400, the first control unit 400 determines whether or not the mixed drug remains in the vial bottle 10B. do. Specifically, the first control unit 400 determines whether or not the mixed chemical remains in the vial bottle 10B according to the difference between the solvent amount and the dispensed amount. That is, when the mixed chemicals are generated in the chemical container 10 in the mixed injection process, the first control unit 400 accommodates the amount of the mixed chemicals produced in the chemical container 10 in the chemical container 10. Take as the default amount of chemicals given. Then, when the first control unit 400 determines that a mixed drug of the drug "Gemzar injection 1 g" and the solvent "physiological saline solution 100 ml" remains, that fact is used as the residual drug information (see FIG. 29 (B)). It is stored in the data storage unit 404. In the residual drug information shown in FIG. 29 (B), only "5 ml" of the mixed drug in which the solvent "physiological saline solution 100 ml" is mixed with the drug name "Gemzar injection 1 g" remains in the vial bottle 10B. It is shown to that effect.

In this case, the first control unit 400 has the same components and the same components as the mixed drug of the drug "Gemzar injection 1 g" and the solvent "physiological saline 100 ml" shown in the residual drug information in the preparation data Rp12 to Rp15. It is determined that the residual drug can be used in the mixed injection treatment for the preparation data Rp14 containing the drug having a mixed ratio as a prescription drug. Since the mixing ratio of the mixed chemicals is determined according to the amount of the component contained in the chemical name and the solvent amount of the solvent, the first control unit 400 is used when the chemical name and the solvent amount are the same. It is possible to determine that the mixing ratio of the mixed chemicals is the same.

Then, as shown in FIG. 29C, the first control unit 400 rearranges the preparation data Rp14 among the preparation data Rp12 to Rp15 to be higher than the preparation data Rp12 and Rp13, and the prescription selection screen. Displayed preferentially on M1. Further, as shown in FIG. 29C, the first control unit 400 prepares the preparation by displaying “◯” on the residual drug presence / absence display unit D21 (see FIG. 29) on the prescription selection screen M1. For the data Rp14, it is indicated that the residual drug can be used. As a result, the user can recognize that the residual drug can be used by subjecting the preparation data Rp14 displayed higher on the prescription selection screen M1 to the next mixed injection process. can.

As shown in FIG. 29 (C), for the preparation data Rp12 in which a drug of a type different from the residual drug is a prescription drug, “◯” is not displayed on the residual drug presence / absence display unit D21. It is indicated that the residual drug cannot be used. Further, as shown in FIG. 29 (C), for the preparation data Rp13 whose solvent amount is different from that of the residual drug, the residual drug is used because “◯” is not displayed on the residual drug presence / absence display unit D21. It is shown that it cannot be done. Further, as shown in FIG. 29C, for the preparation data Rp15 whose solvent is different from that of the residual drug, the residual drug is used because “◯” is not displayed on the residual drug presence / absence display unit D21. It is shown that it cannot be done.

By the way, in the mixed drug, strictly speaking, the volume of the mixed drug increases by the mass of the drug from the amount of the solvent due to the mixing of the drug and the solvent. Therefore, it is considered as another embodiment that the first control unit 400 has a function of managing the remaining drug in consideration of the mass content of the drug. In this case, the first control unit 400 sets the first operation mode in which the mass content of the chemical is taken into consideration and the second operation mode in which the mass content of the chemical is not taken into consideration according to the user operation of the operation unit 405. It is conceivable that it can be switched. In this case, in the data storage unit 404 of the first control unit 400, for example, the mass per unit volume of each drug, the volume per unit mass of each drug, or the volume of each drug name is stored in the drug master. Has been done. For example, it is conceivable that the volume corresponding to the drug name “Gemzar injection 1 g” is stored in the drug master. Then, it is conceivable that the first control unit 400 acquires the volume of the drug based on the drug master and derives the actual volume of the mixed drug.

[Batch preparation inspection function]
By the way, as described above, in the mixed injection device 1, the preparation inspection process is executed in order to inspect the result of the mixed injection process after the completion of the mixed injection process. However, in this case, the preparation inspection process is executed at each end of the mixed injection process, and the user needs to confirm the preparation result each time.

On the other hand, the mixed injection device 1 includes the accommodation unit 700 capable of accommodating a plurality of the trays 101 as described above. Therefore, the mixed injection device 1 stocks a plurality of the trays 101 after the execution of the mixed injection process in the storage unit 700, and collectively executes the preparation inspection process for the preparation data corresponding to each of the trays 101. It is conceivable to have a batch preparation inspection function. Specifically, the mixed injection control unit 100 uses the first control unit 400 or the second control unit 500 to execute the batch preparation inspection process described later according to the first mixed injection control program or the second mixed injection control program. By doing so, the batch preparation inspection function is realized. The second control unit 500 can switch between valid and invalid of the batch preparation inspection function according to a user operation, and the same applies to other functions included in the mixed injection device 1. Here, the mixed injection control unit 100 when executing the batch preparation inspection processing is an example of the accommodation processing unit and the preparation inspection processing unit.

[Batch preparation inspection processing]
Hereinafter, an example of the batch preparation inspection process executed by the mixed injection device 1 when the batch preparation inspection function is effective will be described with reference to FIG. 30.

<Step S61>
First, in step S61, the second control unit 500 determines whether or not the mixed injection process is completed, and if it is determined that the mixed injection process is completed (S61: Yes), the process is shifted to step S62. When it is determined that the mixed injection process has not been completed (S61: No), the process is shifted to step S63.

<Step S62>
In step S62, the second control unit 500 executes a process for stocking the tray 101 in which the infusion bag 12 after the mixed injection process is stored in the storage unit 700. Specifically, the second control unit 500 controls the tray transport unit 110 to return the infusion bag 12 to the tray 101, and the tray 101 is moved from the tray transport end portion 110a to the tray transport start unit 110b. Move to. Subsequently, the second control unit 500 controls the tray transport unit 110 to supply the tray 101 to the storage unit 700 side via the tray loading port 114.

After that, the second control unit 500 controls the storage unit 700 to store the tray 101 in the tray storage unit 811 of the elevating unit 800. At this time, the second control unit 500 updates the correspondence information D31 indicating the correspondence relationship between the identification information of the tray 101 and the tray accommodating unit 811. Further, the second control unit 500 reads the identification information of the tray 101 with the IC reader 930 before the tray 101 is housed in the tray storage unit 811 of the storage unit 700, and prepares the identification information. It is collated with the identification information of the tray 101 associated with the data.

<Step S63>
In step S63, the second control unit 500 determines whether or not a predetermined preparation inspection start operation has been performed on the touch panel monitor 14 or the like. For example, the second control unit 500 causes the touch panel monitor 14 to display a list of the prepared data for which the mixed injection process has been executed in response to a user operation, and when one or a plurality of the prepared data is selected, the second control unit 500 displays the list of the prepared data for which the mixed injection process has been executed. It is determined that the preparation inspection start operation has been performed on one or more of the preparation data. Here, if it is determined that the preparation inspection start operation has been performed (S63: Yes), the process proceeds to step S64, and if the preparation inspection start operation has not been performed (S63: No), the process proceeds to step S61. Is returned to.

<Step S64>
In step S64, the second control unit 500 executes the preparation inspection process for one or more of the preparation data. Specifically, the second control unit 500 sequentially executes the preparation inspection process for one or more of the preparation data selected when the preparation inspection start operation is performed.

The second control unit 500 receives the tray corresponding to the preparation data every time the inspection completion operation indicating that the result of the mixed injection processing is appropriate in the preparation inspection process corresponding to the preparation data is performed. The 101 are sequentially discharged from the storage unit 700 toward the tray discharge port 206. As a result, the user can take out the tray 101 from the tray discharge port 206. The tray 101 is not ejected until the inspection completion operation is performed. That is, the second control unit 500 limits the removal of the tray 101 after the mixed injection process is executed until the result of the mixed injection process is determined to be appropriate in the preparation inspection process.

As described above, in the mixed injection device 1, the batch preparation inspection function enables the preparation inspection processing to be collectively executed in order for each of the preparation data. Therefore, it is not necessary for the user to perform a confirmation operation each time the mixed injection process is completed, and the load on the user operation is reduced.

[Batch agitation inspection function]
Further, in the mixed injection device 1, as described above, the stirring inspection process is executed in order to inspect the stirring result by the stirring step after the completion of the stirring step. On the other hand, the mixed injection device 1 may include the storage unit 700 capable of accommodating the plurality of trays 101 as described above, and may execute the pre-stirring process on the plurality of chemical containers 10. Here, also in the pre-stirring process, when the stirring inspection process is executed at each end of the stirring step, the user needs to confirm the stirring result each time.

Therefore, in the mixed injection device 1, a plurality of the chemical containers 10 after being stirred in the stirring step executed by the plurality of pre-stirring treatments are stocked in the above-mentioned storage rack 33, and the plurality of the chemicals are stored. It is conceivable that the container 10 is provided with a batch stirring inspection function capable of collectively executing the stirring inspection process. Specifically, the mixed injection control unit 100 uses the first control unit 400 or the second control unit 500 to execute the batch stirring inspection process described later according to the first mixed injection control program or the second mixed injection control program. By doing so, the batch stirring inspection function is realized.

[Batch agitation inspection process]
Hereinafter, an example of the batch stirring inspection process executed by the mixed injection device 1 when the batch stirring inspection function is effective will be described with reference to FIG. 31.

<Step S71>
First, in step S71, the second control unit 500 determines whether or not the stirring step is completed, and if it is determined that the stirring step is completed (S71: Yes), the process is shifted to step S72. When it is determined that the stirring step has not been completed (S71: No), the process is shifted to step S73.

<Step S72>
In step S72, the second control unit 500 executes a process for stocking the chemical container 10 after the stirring step on the above-mentioned storage rack 33. Here, the second control unit 500 when executing the processing is an example of the mounting processing unit. Specifically, the second control unit 500 controls the first robot arm 21 to move the chemical container 10 to the above-mentioned storage rack 33. The data storage unit 504 stores the arrangement table information indicating the correspondence between the identification information of the medicine container 10 and the arrangement in the above-mentioned storage shelf 33, and the second control unit 500 stores the arrangement table information. The arrangement table is updated in S72.

<Step S73>
In step S73, the second control unit 500 determines whether or not a predetermined stirring inspection start operation has been performed on the touch panel monitor 14 or the like. For example, when the second control unit 500 causes the touch panel monitor 14 to display a list of the chemical containers 10 for which the stirring step has been executed according to a user operation, and one or a plurality of the chemical containers 10 are selected. In addition, it is determined that the stirring inspection start operation has been performed on one or more of the chemical containers 10. Here, if it is determined that the stirring inspection start operation has been performed (S73: Yes), the process proceeds to step S74, and if the stirring inspection start operation has not been performed (S73: No), the process proceeds to step S71. Returned to.

<Step S74>
In step S74, the second control unit 500 executes the stirring inspection process on one or more of the chemical containers 10 after the stirring stroke placed on the storage shelf 33 described above. Here, the second control unit 500 when executing the processing is an example of the stirring inspection processing unit. Specifically, the second control unit 500 sequentially executes the stirring inspection process for one or more of the chemical containers 10 selected when the stirring inspection start operation is performed.

Then, the second control unit 500 permits the use of the chemical container 10 every time the inspection completion operation is performed in the stirring inspection process corresponding to the chemical container 10. That is, the second control unit 500 limits the use of the chemical container 10 stirred by the pre-stirring process until the stirring inspection process is executed.

As described above, in the mixed injection device 1, the batch stirring inspection function enables the stirring inspection processing to be collectively executed in order for each of the chemical containers 10 that have been the targets of the pre-stirring treatment. Therefore, it is not necessary for the user to perform a confirmation operation every time the stirring step is completed, and the load of the user operation is reduced.

[Batch total collection inspection function]
By the way, in the mixed injection process, when the total amount of the chemicals in the chemical container 10 is collected, the total amount collection inspection may be performed in which the user confirms that no chemicals remain in the chemical container 10. .. For example, after each user is notified of the end of the total amount collection, the progress of the mixed injection process may be restricted until the confirmation operation is performed by the user. In this case, when the total amount of the chemicals is collected for the plurality of the chemical containers 10 in the mixed injection process based on the preparation data, the total amount collection inspection is executed every time the total amount is collected for each of the chemical containers 10. Will be done. Therefore, it is necessary for the user to operate the mixed injection device 1 every time the total amount of each of the chemical containers 10 is collected.

On the other hand, it is conceivable that the mixed injection device 1 has a batch total volume collection inspection function for collectively executing a total volume collection inspection for a plurality of the chemical containers 10. Specifically, the mixed injection control unit 100 uses the first control unit 400 or the second control unit 500 to perform a batch total collection inspection process described later according to the first mixed injection control program or the second mixed injection control program. By executing the above-mentioned batch total amount collection inspection function is realized.

[Batch total collection inspection processing]
Hereinafter, with reference to FIG. 32, an example of the batch total volume collection inspection process executed by the mixed injection device 1 when the batch total volume collection inspection function is effective will be described. In addition, the batch total amount collection inspection process is executed together with the mixed injection process.

<Step S81>
In step S81, the second control unit 500 determines whether or not there are a plurality of the chemical containers 10 to be collected in the mixed injection process based on the preparation data. Here, if it is determined that there are a plurality of the chemical containers 10 to be collected in total (S81: Yes), the process proceeds to step S82, and if there are no plurality of chemical containers 10 to be collected in total. If it is determined (S81: No), the batch total collection process ends.

<Step S82>
In step S82, the second control unit 500 determines whether or not the total amount collection of any of the plurality of the chemicals 10 to be collected is completed. Here, when it is determined that the total amount collection is completed (S82: Yes), the process proceeds to step S83, and when the total amount collection is not completed (S82: No), the process waits in the step S82.

<Step S83>
In step S83, the second control unit 500 controls the first robot arm 21 to place the chemical container 10 to be collected in the total amount determined to have been completed in step S82 on the above-mentioned storage rack 33. Place. At this time, the second control unit 500 stores the chemical container 10 and the arrangement in the above-mentioned storage rack 33 in the data storage unit 504 in association with each other. The above-mentioned storage shelf 33 is an example of the second mounting unit, and the first-mentioned process for mounting the chemical container 10 on the previously described storage shelf 33 after the execution of the total amount collection is executed. 2 The control unit 500 is an example of the second mounting processing unit. In the present embodiment, the above-mentioned storage shelf 33 is an example of the first mounting portion and the second mounting portion, but the first mounting portion and the second mounting portion are individually provided. May be.

<Step S84>
In step S84, the second control unit 500 breaks whether or not the total amount collection has been completed for all of the plurality of the chemical containers 10 that are the target of the total amount collection in the preparation data. Here, when it is determined that all the total amount collection has been completed (S84: Yes), the process proceeds to step S85, and when it is determined that all the total amount collection has not been completed (S84: No), the process Goes to step S82.

<Step S85>
In step S85, the second control unit 500 notifies that the total amount collection has been completed for all of the plurality of the chemical containers 10 that are the target of total amount collection in the preparation data. For example, the second control unit 500 causes the touch panel monitor 14 to display the end of total collection. Further, the second control unit 500 may display the end of total collection on the display 203 via the first control unit 400.

<Step S86>
In step S86, the second control unit 500 determines whether or not the operation to start the total amount collection inspection has been performed on the touch panel monitor 14. Here, if it is determined that the start operation of the total amount collection inspection has been performed (S86: Yes), the process proceeds to step S87, and the process is performed until the start operation of the total amount collection inspection is performed (S86: No). Wait in step S86.

<Step S87>
In step S87, the second control unit 500 sequentially executes a total amount collection inspection process for inspecting the result of the total amount collection for each of the chemical containers 10 after the total amount collection. Here, the second control unit 500 when executing the processing is an example of the total amount collection inspection processing unit. Specifically, in the total amount collection inspection process, the second control unit 500 controls the first robot arm 21 so that the bottom or side surface of the chemical container 10 is in a position and posture visible to the user. The chemical container 10 is moved. After that, when the second control unit 500 receives the inspection confirmation operation of the chemical container 10 by the user, the total amount collection inspection processing for the next chemical container 10 is started. After that, when the total amount collection inspection process for all the chemical containers 10 is completed, the inspection results are stored in the data storage unit 504.

The second control unit 500 controls the first robot arm 21 in response to an operation from the user, and changes the bottom or side surface of the chemical container 10 into a plurality of postures that can be confirmed from a plurality of angles. Can be considered. As a result, the user can check the chemical container 10 from different angles, and can appropriately determine whether or not the total amount of the chemical container 1 has been collected normally. .. Further, the second control unit 500 displays one or a plurality of images in which the bottom or side surface of the chemical container 10 is previously photographed in order without mutating the chemical container 10 to a visible position and posture. Is also possible.

Further, here, a case where the total amount collection inspection process is executed after the completion of all the total amount collections included in the mixed injection process has been described, but as another embodiment, the second control unit 500 performs the batch preparation inspection. It is also conceivable to carry out a total collection inspection process at the time of processing.

[Second Embodiment]
By the way, in the first embodiment, in the step S55 (see FIG. 27), the drug container 10 containing the residual drug is stored in the above-mentioned storage shelf 33 in the mixed injection processing chamber 104. explained. On the other hand, the method for storing the residual drug is not limited to the state of being contained in the drug container 10.

For example, the second control unit 500 controls the first robot arm and the second robot arm 22, and the syringe 11 used in the mixed injection process sucks the remaining medicine in the medicine container 10. By placing the syringe 11 on the above-mentioned storage shelf 33, it is conceivable that the residual drug is stored in the mixed injection processing chamber 104. In this case, the position information of the syringe 11 is stored in the remaining drug information instead of the position information of the drug container 10. In the syringe 11 containing the remaining medicine, the cap 11d is attached to the injection needle 11c by using the injection needle attachment / detachment device 43 before being placed on the above-mentioned storage shelf 33. Further, the second control unit 500 is not the syringe 11 used in the mixed injection process, but the unused syringe 11 previously placed on the storage shelf 33 described above, and the medicine remaining in the medicine container 10. It is also conceivable to suck the syringe 11 and place the syringe 11 on the above-mentioned storage rack 33.

Further, the second control unit 500 controls the first robot arm and the second robot arm 22, and the medicine container 10 is used in a plurality of unused syringes 11 previously placed on the above-mentioned storage rack 33. It is also conceivable to divide and suck the chemicals in the syringe 11 and place each of the syringes 11 on the above-mentioned storage rack 33. At this time, the amount of the drug distributed to each of the syringes 11 may be, for example, a preset predetermined amount or the amount of the drug used in the preparation data scheduled in the future.

According to the configuration in which the syringe 11 sucking the medicine remaining in the medicine container 10 is placed on the above-mentioned storage shelf 33, the second control unit 500 is used in the subsequent mixed injection processing. The medicine contained in the syringe 11 stocked in the storage shelf 33 can be used in the step S53. As a result, in the mixed injection process in which the residual drug is used, the process of sucking the drug from the drug container 10 with the syringe 11 can be omitted.

The second control unit 500 places the drug container 10 in which the drug remains on the previously described shelf 33, or sucks it with the syringe 11 and places it on the previously described shelf 33, depending on the user's operation. It is also possible to choose whether to place it. Further, the second control unit 500 automatically determines whether the chemical container 10 in which the chemical remains is placed on the previously described shelf 33 or is sucked by the syringe 11 and placed on the previously described shelf 33. It is also possible to switch to. For example, if the second control unit 500 can continuously execute the mixed injection process for the preparation data using the drug remaining in the mixed injection process, the drug is sucked by the syringe 11 and described above. It is conceivable to place it on the shelf 33. On the other hand, when the second control unit 500 does not continuously execute the mixed injection process for the preparation data using the chemicals remaining in the mixed injection process as it is (when another mixed injection process is executed in the meantime, etc.) It is conceivable that the chemical container 10 in which the chemical remains is placed on the storage shelf 33 described above.

By the way, the second control unit 500 determines in advance whether or not to place the medicine container 10 in which the medicine remains after the mixed injection treatment or the syringe 11 in which the medicine is sucked from the medicine container 10 on the above-mentioned storage rack 33. It may be switched according to the set conditions. Specifically, in the first stage of the step S54, the second control unit 500 may determine whether or not the drug is of a type preset as a drug to be used as a residual drug in the drug master or the like. .. Further, the second control unit 500 may be able to set whether or not the residual drug is to be used for each of the preparation data or the drug according to the user's operation. Then, it is conceivable that the second control unit 500 executes the step S54 when it is a residual drug utilization target, and executes step S541 described later when it is not a residual drug utilization target.

In this embodiment, the case where the medicine contained in the medicine container 10 or the syringe 11 is reused in the mixed injection device 1 has been described. On the other hand, in step S55, the second control unit 500 can take out the medicine container 10 or the syringe 11 containing the medicine remaining after the mixed injection treatment, and the syringe 10 or the syringe 11 can be taken out. It is also conceivable to transport the syringe to a predetermined syringe dispenser such as the take-out door 302 so that the syringe can be taken out to the outside. Thereby, a user such as a pharmacist can take out the medicine container 10 or the syringe 11 from the syringe dispensing unit and reuse the medicine remaining in the mixed injection treatment in another mixed injection operation. The second control unit 500 determines whether the chemicals remaining after the mixed injection process are left in the mixed injection device 1 or can be taken out from the predetermined take-out unit according to the user operation or preset reuse conditions. It is conceivable to switch based on.

[Third Embodiment]
As described in the first embodiment, the mixed injection process may require a user's work to confirm the suitability of the mixed injection process, and the mixed injection process is performed until the confirmation work is performed by the user. May be suspended. For example, as described above, when the stirring step in the mixed injection process is executed, a confirmation operation for confirming the degree of dissolution of the chemical in the chemical container 10 may be required after the stirring step. Further, when the total amount of the chemicals in the chemical container 10 is collected, a confirmation operation for confirming whether or not the total amount is collected may be required. Further, as described above, a confirmation operation may be required in the preparation inspection process executed after the completion of the mixed injection process.

However, such a confirmation operation is effective when a user is present in the vicinity of the mixed injection device 1, but when the user is absent, the continuous execution of the mixed injection process is hindered. Therefore, in the mixed injection device 1, as the operation mode of the mixed injection process, a normal mode for enabling the user's confirmation operation and an automatic mode for omitting the user's confirmation operation are provided, and the second control unit 500 is described. It is considered that the normal mode and the automatic mode can be switched.

Then, the second control unit 500 effectively sets the batch preparation inspection function, the batch stirring inspection function, and the batch total amount collection inspection function in the automatic mode. Further, the second control unit 500 disables the batch preparation inspection function, the batch stirring inspection function, and the batch total amount collection inspection function in the normal mode. As a result, in the case of the automatic mode, the user does not need to be involved in the continuous execution of the mixed injection process, so that the mixed injection process can be continuously executed.

For example, it is conceivable that the second control unit 500 arbitrarily switches between the normal mode and the automatic mode according to a predetermined user operation on the operation unit 505. It is also conceivable that the second control unit 500 automatically switches between the normal mode and the automatic mode based on a preset time schedule. For example, it is conceivable that the automatic mode is automatically switched to the automatic mode in the midnight time zone when the pharmacist is absent, and the mode is returned to the normal mode except in the midnight time zone. The content of the automatic mode is merely an example. For example, in the automatic mode, among the errors that may occur in the mixed injection process 1, a preset specific error is ignored and the user after executing the mixed injection process. It is conceivable to be notified to.

Further, it is conceivable that the second control unit 500 sets the stirring time in the stirring step to be longer than that in the normal mode in the automatic mode. Further, it is conceivable that the second control unit 500 sets the pulling amount of the plunger 11b to be larger than that in the normal mode when the total amount of the chemicals in the chemical container 10 is collected in the mixed injection process. This reduces the possibility of insufficient stirring in the stirring step or the possibility of chemicals remaining in the chemical container 10.

Further, when the predetermined number or all of the mixed injection processing set in advance is completed in the automatic mode, the first control unit 400 or the second control unit 500 of the mobile terminal that the user has. It is also conceivable to notify a preset destination such as an e-mail address or an SNS account. As a result, the user can efficiently perform the confirmation work in the mixed injection device 1.

[Fourth Embodiment]
In the mixed injection device 1, the second control unit 500 controls the first robot arm 21 or the second robot arm 22, and the holding unit 25 or the holding unit 26 grips the chemical container 10. There is. In this case, the second control unit 500 adjusts the control amount of the first robot arm 21 or the second robot arm 22 with reference to the container shape information of the drug container 10 stored in the drug master. .. For example, the second control unit 500 has the interval between the gripping claws 25a or the gripping claws 261a when the chemical container 10 is held by the holding portion 25 or the holding portion 26, based on the container shape information, and the chemical container. The posture of the drug container 10 when the drug solution is withdrawn from the syringe 10, or the moving speed, puncture depth, and puncture of the injection needle 10c when the injection needle 10c is punctured into the rubber stopper of the vial bottle 10B. The position of is considered.

On the other hand, the manufacturer of the drug container 10 may change the shape of the drug container 10, and in this case, the container shape of the drug container 10 in the drug master stored in the mixed injection device 1. The information will be updated. However, in a medical facility such as a hospital where the mixed injection device 1 is installed, the chemical container 10 before the shape change is also in stock, so that the chemical container 10 after the shape change is actually loaded into the mixed injection device 1. There may be a time lag before it is used.

Therefore, in the mixed injection device 1, it is conceivable that the first control unit 400 can store a plurality of container shape information for the drug container corresponding to each drug in the data storage unit 404 in the drug master. More specifically, it is conceivable that two pieces of information, the latest container shape information of each of the drug containers 10 and the previous container shape information, are registered in the drug master. Then, when the drug master has a plurality of container shape information of the drug container 10, the first control unit 400 refers to the container shape information arbitrarily selected from the plurality of container shape information, and the first control unit 400 refers to the container shape information. It is possible to control the 1-lot arm 21 or the second robot arm.

For example, the first control unit 400 selects the container shape information referred to when the mixed injection process is executed by executing the shape selection process shown in FIG. 33. Here, the first control unit 400 when executing the processing is an example of the shape selection processing unit. When the first control unit 400 reads identification information such as a chemical code from the GS1 data bar attached to the chemical container 10 in step S25 of the loading preparation process (see FIG. 24). The shape selection process is executed. The shape selection process may be executed by the second control unit 500, for example, when the mixed injection process is executed.

<Step S91>
First, it is determined whether or not a plurality of container shape information of the drug container is registered in the drug master for the drug corresponding to the identification information of the drug container 10 read by the barcode reader 204. Here, if it is determined that a plurality of container shape information of the chemical container is registered (S91: Yes), the process proceeds to step S92, and it is determined that a plurality of container shape information of the chemical container is not registered. Then (S91: No), one registered container shape information is adopted and the shape selection process is completed.

<Step S92>
In step S92, the first control unit 400 causes the display 203 to display a selection screen for allowing the user to select a plurality of the container shape information. For example, on the selection screen, for each of the container shape information, the outer diameter of the chemical container, the thickness of the rubber stopper, the puncture position, the depth of the chemical container, the external image of the chemical container, the plan image of the rubber stopper, and the container shape information. Various information such as the registration date of the container is displayed together with the operation keys for selecting the container shape information.

<Step S93>
In step S93, the first control unit 400 waits for the container shape information selection operation (S93: No). Then, when it is determined that the container shape information has been selected (S93: Yes), the process is shifted to step S94.

<Step S94>
In step S94, the first control unit 400 selects the container shape information determined to be selected in step S93 as the container shape information of the chemical container 10 referred to in the mixed injection process based on the preparation data. do. Specifically, the first control unit 400 transmits the selected container shape information to the second control unit 500 when transmitting the execution request of the mixed injection process based on the preparation data to the second control unit 500. Notice. As a result, the second control unit 500 reads the container shape information notified from the first control unit 400 from the drug master and controls the first robot arm 21 and the second robot arm 22. Become.

As described above, in the mixed injection device 1 according to the present embodiment, any one of the plurality of container shape information stored in the drug master is selected, and the first robot arm 21 and the second robot arm 22 are selected. Be controlled. As a result, even if the shape of the chemical container 10 is changed, the container shape information before and after the change can be arbitrarily selected. Therefore, the chemical container 10 before and after the shape change is used. It is possible to do.

It should be noted that the first control unit 400 has the container shape information before and after the change only for a predetermined period (1 month, 2 months, etc.) set in advance after the container shape information of the drug container in the drug master is updated. It is conceivable that the selection of the container shape information before the change cannot be made after the lapse of the predetermined period. Specifically, in step S91, the first control unit 400 may determine whether or not a plurality of container shape information registered within the predetermined period from the present exists. As a result, it is possible to save the user the trouble of selecting the container shape information after the predetermined period has elapsed since the container shape information was registered.

[Fifth Embodiment]
In the mixed injection device 1, there is a possibility that an error in attaching the holding portion 26 to the second robot arm 22 may occur. For example, there is a possibility that the central axis of the joint at the tip of the second robot arm 22 and the central axis of the holding portion 26 are displaced from each other. Then, when such an attachment error occurs, accurate control using the holding portion 26 of the second robot arm 22 is not executed.

Therefore, the error detection function for detecting the attachment error of the holding unit 26 to the second robot arm 22 by the second control unit 500 using the needle bending detection unit 36 and the error detected by the error detection function Based on this, it is conceivable to have an error correction function for correcting the operation of the second robot arm 22.

For example, as shown in FIG. 34, a jig 90 having a needle-shaped tip portion 91 is mounted at a predetermined position of the holding portion 26 of the second robot arm 22. The jig 90 may be gripped by the grip portion 26. Then, the second control unit 500 inserts the tip portion 91 into the detection region of the needle bending detection unit 36. After that, the second control unit 500 controls the second robot arm 22 to move the holding unit 26 in one or a plurality of preset directions with respect to the detection area of the needle bending detecting unit 36. Acquires the detection position of the jig 90 at the time.

Specifically, on the detection surface formed by the light emitted from each of the first optical sensor 361 and the second optical sensor 362 in the elongated hole 36a of the needle bending detection unit 36, the vertical direction is the X-axis and the elongated hole 36a. The insertion / removal direction is the Y-axis, and the X-axis and the direction perpendicular to the Y-axis are the Z-axis. In this case, the second control unit 500 detects the position of the tip portion 91 of the jig 90 when the holding portion 26 of the second robot arm 22 is moved along the Y-axis direction. Then, the second control unit 500 detects the value obtained by dividing the movement amount of the tip portion 91 on the X axis by the movement amount on the Y axis as the deviation angle in the X axis direction, and detects the Z axis of the tip portion 91. The value obtained by dividing the amount of movement on the Y-axis by the amount of movement on the Y-axis is detected as the deviation angle in the Z-axis direction. After that, the second control unit 500 corrects the control amount of the holding unit 26 of the second robot arm 22 based on the deviation angle on the X axis and the deviation angle on the Z axis. As a result, in the mixed injection device 1, accurate control is realized by correcting the attachment error of the holding portion 26 with respect to the second robot arm 22.

[Sixth Embodiment]
Here, FIG. 35 is a view showing a plan view of the rubber stopper of the mixed injection port of the infusion bag 12. As shown in FIG. 35, one or a plurality of recesses 12b may be formed on the surface 12a of the rubber stopper of the mixed injection port of the infusion bag 12 at the puncture position of the injection needle 11c of the syringe 11. Here, when the injection needle 11c is punctured into the recess 12b and the drug solution is injected or sucked in the mixed injection process, the drug solution adhering to the recess 12b of the infusion bag 12 taken out after the mixed injection process is cotton. It may be wiped off with a ball or the like. However, since the recess 12b is recessed from the surface 11a of the rubber stopper, even if a cleaning member such as a cotton ball is pressed against the surface of the rubber stopper to adsorb the chemical solution, the cleaning member remains in the recess 12b. The chemical solution may remain in a position that cannot be reached. In particular, when the depth of the recess 12b is deep or the area of the recess 12b is small, it becomes difficult to remove the chemical solution with the cleaning member.

Therefore, when the second control unit 500 controls the second robot arm 52 to puncture the injection needle 11c of the syringe 11 into the rubber stopper of the infusion bag 12, the surface 12a of the rubber stopper is described as described above. It is conceivable to puncture the injection needle 11c into the flat surface portion 12c avoiding the recess 12b. For example, a camera is provided at the tip of the second robot arm 52 or the inner surface of the mixed injection processing chamber 104 at a position where the rubber stopper of the infusion bag 12 can be photographed, and the second control unit 500 is used. It is conceivable to detect the position of the recess 12b by image analysis based on the captured image taken by the camera. In this way, when the injection needle 11c is punctured by the rubber stopper by the flat surface portion 12c avoiding the recess 12b, and the chemical solution adheres to the puncture site of the injection needle 11c, the chemical solution is used as a cotton ball or the like. It is possible to easily clean with the cleaning member of.

[7th Embodiment]
In the mixed injection device 1, in the suction step of sucking the drug solution from the vial bottle 10B using the syringe 11, the plunger 11b of the syringe 11 is controlled, and the step of sucking the drug solution from the vial bottle 10B and the inside of the syringe 11a. The step of injecting air from the syringe 11 into the vial bottle 10B may be repeated a plurality of times. This prevents the inside of the syringe 11 from becoming too positive pressure and the inside of the chemical solution container 10 from becoming too negative pressure.

For example, as shown in FIG. 36 (A), for the first time, the injection needle 11c is punctured into the vial bottle 10B with air in the syringe 11a, and the plunger 11b is pulled to the vial bottle. The chemical is sucked from 10B. As a result, as shown in FIG. 36 (B), the medicine is sucked into the syringe 11a from the vial bottle 10B. Subsequently, the plunger 11b is pushed and the air in the syringe 11a is injected into the vial bottle 10B.

Then, similarly, as shown in FIG. 36C, the injection needle 11c is punctured into the vial bottle 10B, the plunger 11b is pulled, and the drug is sucked from the vial bottle 10B. As a result, as shown in FIG. 36 (D), the medicine is sucked into the syringe 11a from the vial bottle 10B. Subsequently, the plunger 11b is pushed and the air in the syringe 11a is injected into the vial bottle 10B.

By the way, in the suction step, the larger the amount of pulling the plunger 11b of the injector 11 at one time, the larger the amount of chemical solution that can be sucked at one time. Since the number of repetitions with the injection step is reduced, the time required for the suction step is shortened. Therefore, in the suction step, it is desirable that a large amount of the plunger 11b of the syringe 11 is pulled at one time so that the pressure inside the chemical solution container 10 does not become too negative. That is, in the suction step, it is desirable to suck as much chemical solution as possible within the range where the pressure inside the vial bottle 10B does not become too negative at one time.

Here, immediately before the first suction of the drug solution in the suction step, the air pressure in the vial bottle 10B and the volume of the air layer portion in the vial bottle 10B are known. However, when the air in the plunger 11b is injected into the vial bottle 10B after sucking the chemical solution, the chemical solution in the plunger 11b may return to the vial bottle 10B. Therefore, it is not possible to accurately calculate the air pressure in the vial bottle 10B after the second and subsequent suctions of the drug solution.

For example, the volume of the air layer portion in the vial bottle 10B before pulling the plunger 10b for the first time is V1, and the chemical solution corresponding to the pulling amount of the plunger 10b by pulling the plunger 10b for the first time (distance minus the plunger 10b). And the volume of the cross-sectional area of the syringe 10a) is sucked into the syringe 10a, and the volume of the air layer portion in the vial bottle 10B is defined as V2. Further, when the air pressure in the vial bottle 10B before pulling the plunger 10b for the first time is P', it is set as the air pressure P in the vial bottle 10B after pulling the plunger 10b for the first time. In this case, the atmospheric pressure P is represented by P = (V1 / V2) × P'. Here, the volume V1 is dissolved from the volume of the vial bottle 10B when the chemical solution in the vial bottle 10B (when the infusion solution is injected into the vial bottle 10B and the powdery chemical in the vial bottle 10B is dissolved). It is the value obtained by subtracting the volume of the later liquid). That is, the larger the pulling amount of the plunger 10b, the larger the volume of the air layer portion, and the lower the air pressure in the vial bottle 10B. Then, at the first time, the volume of the infusion solution injected into the vial bottle 10B is the amount of the infusion solution sucked from the infusion bag 12 and injected into the vial bottle 10B, and the volume of the infusion solution before pulling the plunger 10b is clear. The volume of the air layer portion in the vial bottle 10B can be calculated.

On the other hand, after the plunger 10b is pulled for the first time and the drug solution is sucked from the vial bottle 10B, the drug solution is injected into the vial bottle 10B when the air in the syringe 10a is injected into the vial bottle 10B. There is a risk. Therefore, the volume of the air layer portion in the vial bottle 10B before pulling the plunger 10b for the second time is unknown, and the volume V1 cannot be calculated accurately after the second time.

Therefore, the second control unit 500 maximizes the pulling amount of the plunger 10b at the time of the first suction within the lower limit of the internal pressure that the vial bottle 10B can withstand within the range where the atmospheric pressure P does not fall. On the other hand, it is conceivable that the second control unit 500 may reduce the pulling amount of the plunger 10b at the time of the second and subsequent suctions to be smaller than the pulling amount of the plunger 10b at the time of the first suction. More specifically, the second control unit 500 sets the pulling amount of the plunger 11b to a pulling amount preset according to the atmospheric pressure in the vial bottle 10B at the time of sucking the chemical solution for the first time, or the pulling amount is described. The pulling amount is set to be calculated according to a preset calculation formula based on the air pressure in the vial bottle 10B. On the other hand, in the suction step, the second control unit 500 pulls the plunger 11b less than the control amount corresponding to the first suction of the drug solution at the time of the second and subsequent suctions of the drug solution (first time). Set to the amount of pulling for a predetermined ratio to the amount of pulling).

As a result, as much chemical solution as possible can be sucked within the range where the inside of the vial bottle 10B does not become too negative pressure at the time of sucking the medicine for the first time, and at the time of sucking the medicine after the second time, the inside of the vial bottle 10B is sucked. It is possible to carry out the suction step so that the pressure does not become too negative. In the suction step, it is conceivable that the pulling amount is set to about 80% or 90% of the pulling amount immediately before the second and subsequent times.

1 Mixed injection device 10 Chemical container 11 Syringe 12 Infusion bag 21 1st robot arm 22 2nd robot arm 31 Ampoule cutter 32 Stirring device 33 Mounting shelf 34 Chemical reading unit 35 Weighing meter 36 Needle bending detection unit 37 Mixed injection communication port 100 Mixed injection control Unit 101 Tray 101a Electronic paper 101b IC tag 101c IC reader 110 Tray transfer unit 200 Chemical loading unit 300 Mixed injection processing unit 400 First control unit 500 Second control unit 600 Upper system 700 Accommodation unit 800 Elevating unit 900 Tray transfer unit

Claims (4)

A mixed injection device including a mixed injection processing unit capable of performing a mixed injection process of injecting a chemical in a first container into a second container based on preparation data, and a mixed injection control unit for controlling the mixed injection processing unit.
The mixed injection control unit is executed in the mixed injection device at a preset reference time point for chemicals of the same type as the chemicals used in the mixed injection processing by the mixed injection processing unit executed based on the preparation data selected as the processing target. When the amount of residual liquid remaining is greater than or equal to the amount of chemicals required for the mixed injection process based on the preparation data, a message for instructing reading of the identification information attached to the first container is displayed. Alternatively, when the identification information is read, a display screen on which it is possible to select whether or not to use the chemical remaining in the mixed injection device is displayed on the display unit.
Mixed injection device. The residual liquid amount is the amount of the chemical whose expiration date does not reach at the start of the mixed injection process based on the preparation data.
The mixed injection device according to claim 1. The mixed injection control unit is a message indicating that the residual liquid amount is equal to or more than the prescribed amount of the drug shown in the preparation data, or the tray loaded in the mixed injection device in association with the preparation data. 1 A message indicating that the mixed injection process based on the preparation data can be performed using only the chemicals remaining in the mixed injection device without placing the container is displayed on the display screen.
The mixed injection device according to claim 1 or 2. In the control unit of the mixed injection device provided with the mixed injection processing unit capable of performing the mixed injection processing of injecting the chemicals in the first container into the second container based on the preparation data.
The amount of residual liquid remaining in the mixed injection device at a preset reference time point for chemicals of the same type as those used in the mixed injection processing by the mixed injection processing unit executed based on the preparation data selected as the processing target. If the amount of chemicals required for the mixed injection process based on the preparation data is greater than or equal to the amount required , a message for instructing reading of the identification information attached to the first container is displayed or the identification information is read. A step to display a display screen on the display unit that can select whether or not to use the chemicals remaining in the mixed injection device.
A program to execute.

Images