JP7265271B2 - Beauty and health composition, and pharmaceuticals or food and drink containing the beauty and health composition - Google Patents
Beauty and health composition, and pharmaceuticals or food and drink containing the beauty and health composition Download PDFInfo
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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Description
本発明は、美容健康用組成物、及び当該美容健康用組成物を含む医薬品又は飲食品に関する。 TECHNICAL FIELD The present invention relates to a beauty and health composition, and a pharmaceutical product or food and drink containing the beauty and health composition.
美容及び健康を増進させる美容健康用組成物が、種々開発されている。
このような組成物として、例えば特許文献１に、銀ナノ粒子を含有するナノ活性剤が開示されている。
Various beauty and health compositions for promoting beauty and health have been developed.
As such a composition, for example, Patent Document 1 discloses a nano-active agent containing silver nanoparticles.
銀ナノ粒子は、ヒトの皮膚に塗布されると、抗菌効果、保湿効果、及びシミ改善効果を発揮すると考えられている。
特に、銀ナノ粒子による抗菌効果については、例えば特許文献２～５に記載されている通り、比較的多くの文献で報告されている。
Silver nanoparticles are believed to exert antibacterial, moisturizing, and anti-blemish effects when applied to human skin.
In particular, the antibacterial effect of silver nanoparticles has been reported in a relatively large number of documents, for example, as described in Patent Documents 2 to 5.
銀ナノ粒子による保湿効果、及びシミ改善効果については、報告する文献が比較的少なく、その効き目には個人差がある虞がある。
そのため、銀ナノ粒子を含有するナノ活性剤を塗布しても、保湿効果、及びシミ改善効果を得られない虞がある。
There are relatively few documents reporting the moisturizing effect and stain-improving effect of silver nanoparticles, and there is a possibility that the effect may vary from person to person.
Therefore, even if a nano-active agent containing silver nanoparticles is applied, there is a possibility that a moisturizing effect and a blemish-improving effect cannot be obtained.
本発明は、上記問題点に鑑みてなされたものであり、従来の銀ナノ粒子を含有する組成物よりも、保湿効果及びシミ改善効果を発揮することが可能な美容健康用組成物、及び当該美容健康用組成物を含む医薬品又は飲食品を提供することを目的とする。 The present invention has been made in view of the above problems, and a composition for beauty and health that can exhibit a moisturizing effect and an effect for improving dark spots more than conventional compositions containing silver nanoparticles, and the The purpose is to provide pharmaceuticals or food and drink containing compositions for beauty and health.
上記目的を達成するため、本発明の美容健康用組成物は、銀ナノ粒子と、食用珪素と、を含有し、
前記銀ナノ粒子による殺菌効果を高める目的で、前記銀ナノ粒子は、四酸化四銀（Ａｇ
４Ｏ４）の膜でコーティングされていることを含み、
経口投与される。
In order to achieve the above object, the beauty and health composition of the present invention contains silver nanoparticles and edible silicon,
For the purpose of enhancing the bactericidal effect of the silver nanoparticles, the silver nanoparticles are tetrasilver tetroxide (Ag
4 O 4 ) , including being coated with a film of
Administered orally .
本発明によれば、従来の銀ナノ粒子を含有する組成物よりも、保湿効果及びシミ改善効果を発揮することが可能な美容健康用組成物、及び当該美容健康用組成物を含む医薬品又は飲食品を提供することができる。 According to the present invention, a beauty and health composition capable of exhibiting a moisturizing effect and a stain-improving effect more than a conventional composition containing silver nanoparticles, and a pharmaceutical or food and drink containing the beauty and health composition can provide goods.
以下、本発明の実施の形態に係る美容健康用組成物について説明する。 BEST MODE FOR CARRYING OUT THE INVENTION A beauty and health composition according to an embodiment of the present invention will be described below.
本発明の美容健康用組成物は、有効成分として、銀ナノ粒子と、食用珪素と、を含有する。 The beauty and health composition of the present invention contains silver nanoparticles and edible silicon as active ingredients.
銀ナノ粒子は、銀のナノ粒子である。
銀ナノ粒子の粒子径は、特に限定されず、例えば１ｎｍ以上１００ｎｍ以下であってもよい。つまり、銀ナノ粒子の粒子径は、５ｎｍであってもよく、１０ｎｍであってもよく、１５ｎｍであってもよく、３０ｎｍであってもよく、４０ｎｍであってもよく、７０ｎｍであってもよい。
Silver nanoparticles are nanoparticles of silver.
The particle size of the silver nanoparticles is not particularly limited, and may be, for example, 1 nm or more and 100 nm or less. That is, the particle diameter of the silver nanoparticles may be 5 nm, 10 nm, 15 nm, 30 nm, 40 nm, or 70 nm. good.
また、銀ナノ粒子は、分散媒中に分散した銀のコロイド粒子である。
つまり、本発明の美容健康用組成物の製造工程には、銀のコロイド粒子（銀ナノ粒子）が分散媒中に分散したコロイド溶液と、食用珪素とが混合される工程を含む。
そして、その混合により形成された混合物中の銀ナノ粒子及び食用珪素が、本発明の美容健康用組成物の有効成分となる。
なお、分散媒は水であり、具体的には純水、蒸留水、水道水などが挙げられるが、特に純水が好ましい。
Silver nanoparticles are colloidal particles of silver dispersed in a dispersion medium.
That is, the manufacturing process of the beauty and health composition of the present invention includes a step of mixing a colloidal solution in which colloidal silver particles (silver nanoparticles) are dispersed in a dispersion medium and edible silicon.
Then, the silver nanoparticles and edible silicon in the mixture formed by the mixing become the active ingredients of the composition for beauty and health of the present invention.
The dispersion medium is water, and specific examples thereof include pure water, distilled water, and tap water. Pure water is particularly preferred.
銀ナノ粒子が分散媒中に分散したコロイド溶液の製造方法は、特に限定されず、公知の方法であってもよい。
公知の方法としては、例えば、特開第２００９－０１９２３５号公報に開示されている銀ナノ粒子の分散液の製造方法であって、酸化銀、ゼラチン、及び単糖類を混合し、水溶媒中、５５～８０℃で加熱する方法が挙げられる。
A method for producing a colloidal solution in which silver nanoparticles are dispersed in a dispersion medium is not particularly limited, and a known method may be used.
As a known method, for example, a method for producing a dispersion of silver nanoparticles disclosed in Japanese Patent Application Laid-Open No. 2009-019235, wherein silver oxide, gelatin, and monosaccharides are mixed, and in an aqueous solvent, A method of heating at 55 to 80°C may be mentioned.
銀ナノ粒子は、その殺菌効果を高める為に、合成が加えられていてもよい。このような合成が加えられた物質（以下、「物質Ａ」という）としては、特に限定されないが、例えば、銀ナノ粒子が四酸化四銀（Ａｇ４Ｏ４）の膜でコーティングされた物質を挙げることができる。
なお、本発明の美容健康用組成物の有効成分として物質Ａが含有される場合、本発明の美容健康用組成物の製造工程には、物質Ａが分散媒中に分散した分散液と、食用珪素とが、混合される工程を含んでもよい。なお、分散媒は水であり、具体的には純水、蒸留水、水道水などが挙げられるが、特に純水が好ましい。
The silver nanoparticles may be synthetically added to enhance their bactericidal efficacy. The substance to which such synthesis has been added (hereinafter referred to as “substance A”) is not particularly limited, but for example, a substance in which silver nanoparticles are coated with a film of tetrasilver tetroxide (Ag 4 O 4 ). can be mentioned.
When substance A is contained as an active ingredient in the composition for beauty and health of the present invention, the manufacturing process of the composition for beauty and health of the present invention includes a dispersion liquid in which substance A is dispersed in a dispersion medium, and an edible A step of mixing with silicon may also be included. The dispersion medium is water, and specific examples thereof include pure water, distilled water, and tap water. Pure water is particularly preferred.
物質Ａが分散媒中に分散した分散液の製造方法は、特に限定されず、公知の方法であってもよい。
公知の方法としては、例えば、特許第５１６１２３１号公報に開示されているコロイド状銀組成物の製造方法であって、（ａ）銀電極を高純度の水と接触させて配置し、（ｂ）銀電極を通じて電流を伝達することにより、水内に懸濁する銀粒子の生成を引き起こし、（ｃ）その間、水を撹拌することにより、水内に銀粒子を均一な濃度で分散させる方法が挙げられる。
A method for producing a dispersion in which substance A is dispersed in a dispersion medium is not particularly limited, and a known method may be used.
As a known method, for example, a method for producing a colloidal silver composition disclosed in Japanese Patent No. 5161231 comprises (a) placing a silver electrode in contact with high-purity water, and (b) (c) agitating the water during which an electric current is transmitted through the silver electrode to cause the silver particles to be suspended in the water to disperse the silver particles in the water at a uniform concentration; be done.
銀ナノ粒子は、市販されている、分散媒中に分散した銀のコロイド粒子であってもよい。なお、ここでいう銀ナノ粒子には、物質Ａが含まれる。
市販されている、分散媒中に分散した銀のコロイド粒子としては、特に限定されないが、例えば、Ａｍｅｒｉｃａｎ Ｂｉｏｔｅｃｈ Ｌａｂｓ社から販売されている商品である「ＳＩＬＶＥＲ ＢＩＯＴＩＣＳ（登録商標）」に含有されている銀のコロイド粒子が挙げられる。
The silver nanoparticles may be commercially available colloidal particles of silver dispersed in a carrier medium. In addition, the substance A is contained in the silver nanoparticles here.
Commercially available colloidal particles of silver dispersed in a dispersion medium are not particularly limited. Examples include colloidal particles of silver.
食用珪素は、非晶質珪素であり、例えば、食物由来の珪素や、鉱物由来の珪素が挙げられる。
食物由来の珪素としては、穀類、野菜類、海藻類などに含まれる珪素が挙げられる。
穀類としては、例えば、麦、玄米、白米、トウモロコシである。
野菜類としては、例えば、ゴボウ、大根、人参である。
海藻類としては、例えば、昆布、ワカメである。
穀類、野菜類、海藻類などの食物は、粉砕された状態で、本発明の美容健康用組成物に含有されていてもよい。
Edible silicon is amorphous silicon, and examples thereof include silicon derived from food and silicon derived from minerals.
Food-derived silicon includes silicon contained in grains, vegetables, seaweeds, and the like.
Cereals include, for example, wheat, brown rice, white rice, and corn.
Examples of vegetables include burdock, radish, and carrot.
Examples of seaweed include kelp and wakame.
Foods such as cereals, vegetables, and seaweeds may be contained in the beauty and health composition of the present invention in a pulverized state.
鉱物由来の珪素としては、水晶から抽出した珪素が挙げられる。 Mineral-derived silicon includes silicon extracted from crystal.
また、食用珪素は、市販の食用珪素であってもよく、例えば、株式会社ＡＰＡコーポレーションから販売されている水溶性珪素「ｕｍｏ（登録商標）」に含まれている珪素が挙げられる。なお、水溶性珪素「ｕｍｏ（登録商標）」に含まれている珪素の含有量は、８０００ｐｐｍ以上９３００ｐｐｍ以下である。 The edible silicon may be commercially available edible silicon, for example, silicon contained in water-soluble silicon “umo (registered trademark)” sold by APA Corporation. The content of silicon contained in the water-soluble silicon “umo (registered trademark)” is 8000 ppm or more and 9300 ppm or less.
また、食用珪素は、単体の珪素であってもよいし、例えば二酸化珪素のように化合物中の珪素であってもよい。 The edible silicon may be silicon alone or silicon in a compound such as silicon dioxide.
食用珪素は、人体に摂取されると、腸管から吸収されて、細胞中のミトコンドリアを活性化しつつ、体内の活性酸素の過剰な増加を防ぐ。
つまり、食用珪素を摂取すると、その抗酸化作用により、保湿効果及びシミ改善効果を図ることが可能になる。
When edible silicon is ingested by the human body, it is absorbed from the intestinal tract and activates mitochondria in cells while preventing an excessive increase in active oxygen in the body.
In other words, when edible silicon is ingested, it is possible to obtain moisturizing effects and blemish-improving effects due to its antioxidant action.
このような本発明の美容健康用組成物によれば、銀ナノ粒子の抗菌作用に加え、食用珪素の抗酸化作用が得られる。
そのため、本発明の美容健康用組成物を摂取することで、抗菌効果、保湿効果、及びシミ改善効果を得ることが可能になる。
そして、本発明の美容健康用組成物を摂取することで、銀ナノ粒子を主要な有効成分とする組成物を摂取する場合と比較して、保湿効果及びシミ改善効果を得ることが可能になる。
According to such a beauty and health composition of the present invention, in addition to the antibacterial action of silver nanoparticles, the antioxidant action of edible silicon can be obtained.
Therefore, by ingesting the beauty and health composition of the present invention, it is possible to obtain an antibacterial effect, a moisturizing effect, and an anti-blemish effect.
By ingesting the composition for beauty and health of the present invention, it is possible to obtain a moisturizing effect and an effect of improving dark spots as compared with the case of ingesting a composition containing silver nanoparticles as a main active ingredient. .
また、活性酸素が一因とされる病気を改善することも、可能である。
活性酸素が一因とされる病気としては、特に限定されないが、例えば、動脈硬化、心筋梗塞、癌、糖尿病、肌荒れなどの病気が挙げられる。
It is also possible to ameliorate diseases in which active oxygen is considered to be a factor.
Diseases in which active oxygen is a factor are not particularly limited, but include, for example, diseases such as arteriosclerosis, myocardial infarction, cancer, diabetes, and rough skin.
ここで、本発明の美容健康用組成物に含まれる銀ナノ粒子及び食用珪素の含有量は、特に限定されない。
ただし、食用珪素の含有量が、銀ナノ粒子の含有量よりも多いことが好ましい。
さらに、本発明の美容健康用組成物中の食用珪素の含有量に対する銀ナノ粒子の含有量は、０．０１質量％以上０．２０質量％以下であることが好ましく、０．０５質量％以上０．１５質量％以下であることがさらに好ましく、０．１０質量％であることが最も好ましい。
なお、本発明の美容健康用組成物中の食用珪素の含有量に対する銀ナノ粒子の含有量について、好ましいのは０．０１質量％以上０．２０質量％以下であるから、例えば０．０２質量％、０．０３質量％、０．０４質量％、０．０６質量％、０．０７質量％、０．０８質量％、０．０９質量％、０．１１質量％、０．１２質量％、０．１３質量％、０．１４質量％、０．１６質量％、０．１７質量％、０．１８質量％及び０．１９質量％が含まれる。
これにより、抗菌効果、保湿効果、及びシミ改善効果を、より所望な程度に発揮することが可能になると考えられる。
Here, the contents of silver nanoparticles and edible silicon contained in the beauty and health composition of the present invention are not particularly limited.
However, the content of edible silicon is preferably higher than the content of silver nanoparticles.
Furthermore, the content of silver nanoparticles relative to the content of edible silicon in the composition for beauty and health of the present invention is preferably 0.01% by mass or more and 0.20% by mass or less, and is preferably 0.05% by mass or more. It is more preferably 0.15% by mass or less, and most preferably 0.10% by mass.
The content of silver nanoparticles relative to the content of edible silicon in the composition for beauty and health of the present invention is preferably 0.01% by mass or more and 0.20% by mass or less, so for example 0.02% by mass. %, 0.03% by mass, 0.04% by mass, 0.06% by mass, 0.07% by mass, 0.08% by mass, 0.09% by mass, 0.11% by mass, 0.12% by mass, 0.13 wt%, 0.14 wt%, 0.16 wt%, 0.17 wt%, 0.18 wt% and 0.19 wt%.
It is believed that this makes it possible to exhibit antibacterial effects, moisturizing effects, and anti-blemish effects to a more desired degree.
また、本発明の美容健康用組成物の総質量に基づく銀ナノ粒子の含有量が、０．００１質量％以上１．０質量％以下であってもよい。
なお、本発明の美容健康用組成物の総質量に基づく銀ナノ粒子の含有量について、０．００１質量％以上１．０質量％以下であってもよいから、例えば０．００５質量％、０．０１質量％、０．０５質量％、０．１０質量％、０．１５質量％、０．２０質量％、０．２５質量％、０．３０質量％、０．３５質量％、０．４０質量％、０．４５質量％、０．５０質量％、０．５５質量％、０．６０質量％、０．６５質量％、０．７０質量％、０．７５質量％、０．８０質量％、０．８５質量％、０．９０質量％及び０．９５質量％が含まれる。
Moreover, the content of silver nanoparticles based on the total mass of the beauty and health composition of the present invention may be 0.001% by mass or more and 1.0% by mass or less.
In addition, the content of silver nanoparticles based on the total mass of the beauty and health composition of the present invention may be 0.001% by mass or more and 1.0% by mass or less. 0.01% by weight, 0.05% by weight, 0.10% by weight, 0.15% by weight, 0.20% by weight, 0.25% by weight, 0.30% by weight, 0.35% by weight, 0.40% by weight % by mass, 0.45% by mass, 0.50% by mass, 0.55% by mass, 0.60% by mass, 0.65% by mass, 0.70% by mass, 0.75% by mass, 0.80% by mass , 0.85%, 0.90% and 0.95% by weight.
なお、本発明は、上記実施の形態に限定されず、種々の変形及び応用が可能である。 The present invention is not limited to the above embodiments, and various modifications and applications are possible.
例えば、本発明の美容健康用組成物は、必要に応じて、さらに、食用珪素とは関連しない成分であって、抗酸化作用を奏する成分を含んでもよい。
このような抗酸化作用を奏する成分としては、特に限定されないが、例えば、γ－オリザノール、アルファリポ酸、カテキン類、フラボノイド、コエンザイムＱ１０、ビタミンＣ、ビタミンＥ、エンゾジノール、ローヤルゼリー、尿酸、クエン酸などを挙げることができる。
本発明の美容健康用組成物は、必要に応じて、これらの抗酸化作用を奏する成分の少なくとも１つ以上を含有してもよい。
For example, the beauty and health composition of the present invention may optionally contain a component that is not related to edible silicon and has an antioxidant action.
Ingredients that exhibit such antioxidant activity are not particularly limited, but examples include γ-oryzanol, alpha lipoic acid, catechins, flavonoids, coenzyme Q10, vitamin C, vitamin E, enzogenol, royal jelly, uric acid, citric acid, and the like. can be mentioned.
The beauty and health composition of the present invention may contain at least one or more of these antioxidant action ingredients, if necessary.
そして、本発明の美容健康用組成物に、上記のγ－オリザノール、アルファリポ酸、カテキン類、フラボノイド、コエンザイムＱ１０、ビタミンＣ、ビタミンＥ、エンゾジノール、ローヤルゼリー、尿酸、クエン酸などを含有させる場合、それらの含有量は、特に限定されない。 When the composition for beauty and health of the present invention contains γ-oryzanol, alpha lipoic acid, catechins, flavonoids, coenzyme Q10, vitamin C, vitamin E, enzogenol, royal jelly, uric acid, citric acid, etc., Their content is not particularly limited.
また、本発明の美容健康用組成物は、必要に応じて、賦形剤、ｐＨ調整剤、清涼化剤、懸濁化剤、コーティング剤、着色剤、結合剤、滑沢剤、及び界面活性剤などを含有してもよい。 In addition, the beauty and health composition of the present invention may optionally contain excipients, pH adjusters, cooling agents, suspending agents, coating agents, coloring agents, binders, lubricants, and surfactants. It may contain an agent or the like.
賦形剤としては、特に限定されず、例えば、デンプン、乳糖、白糠、ラクトース、微結晶セルロース、スクロース、デキストリン、Ｄ－マンニトール、コーンスターチ、リン酸カルシウム、リン酸水素カルシウム、硫酸カルシウム、カルボキシメチルスターチナトリウム、メタケイ酸有アルミン酸マグネシウム、ポリエチレングリコール、中鎖脂肪酸トリグリセリドなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上の賦形剤を含有してもよい。
Excipients are not particularly limited, and examples include starch, lactose, rice bran, lactose, microcrystalline cellulose, sucrose, dextrin, D-mannitol, cornstarch, calcium phosphate, calcium hydrogen phosphate, calcium sulfate, sodium carboxymethyl starch, Examples include magnesium alometasilicate, polyethylene glycol, and medium-chain fatty acid triglycerides.
The beauty and health composition of the present invention may contain one or more of these excipients, if desired.
ｐＨ調整剤としては、特に限定されず、例えば、クエン酸、乳酸、リンゴ酸、アスパラギン酸、重曹、水酸化ナトリウム、リン酸水素ナトリウム、水酸化カリウム、水酸化マグネシウムなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上のｐＨ調整剤を含有してもよい。
The pH adjuster is not particularly limited, and examples thereof include citric acid, lactic acid, malic acid, aspartic acid, sodium bicarbonate, sodium hydroxide, sodium hydrogen phosphate, potassium hydroxide, and magnesium hydroxide.
The beauty and health composition of the present invention may contain one or more of these pH adjusters, if desired.
清涼化剤としては、特に限定されず、例えば、ｌ－メントール、ハッカ水などが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上の清涼化剤を含有してもよい。
The cooling agent is not particularly limited, and examples thereof include 1-menthol, peppermint water, and the like.
The beauty and health composition of the present invention may contain one or more of these cooling agents, if desired.
懸濁化剤としては、特に限定されず、例えば、カルボキシメチルセルロース、ヒドロキシメチルセルロース、ポリビニルアルコール、ポリビニルピロリドン、カオリン、カルメロースナトリウムなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上の懸濁化剤を含有してもよい。
Suspending agents are not particularly limited, and examples thereof include carboxymethylcellulose, hydroxymethylcellulose, polyvinyl alcohol, polyvinylpyrrolidone, kaolin, carmellose sodium and the like.
The cosmetic and health composition of the present invention may contain one or more of these suspending agents, if desired.
コーティング剤としては、特に限定されず、例えば、ヒドロキシメチルセルロース、ヒドロキシプロピルセルロース、カルボキシメチルエチルセルロース、ポリオキシエチレングリコール、セルロースアセテートフタレート、ポリビニルアセタールジエチルアミノアセテート、セルロースアセテートトリメリテート、ポリビニルアセテートフタレート、ヒドロキシプロピルメチルセルロースアセテートサクシネート、ヒドロキシプロピルメチルセルロースフタレート、メタクリレートコポリマーなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上のコーティング剤を含有してもよい。
The coating agent is not particularly limited, and examples thereof include hydroxymethylcellulose, hydroxypropylcellulose, carboxymethylethylcellulose, polyoxyethylene glycol, cellulose acetate phthalate, polyvinyl acetal diethylaminoacetate, cellulose acetate trimellitate, polyvinyl acetate phthalate, and hydroxypropylmethylcellulose. Acetate succinate, hydroxypropyl methylcellulose phthalate, methacrylate copolymers, and the like.
The beauty and health composition of the present invention may contain one or more of these coating agents, if desired.
着色剤としては、特に限定されず、例えば、タール色素、酸化チタン、ウコン抽出液、リボフラビンなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上の着色剤を含有してもよい。
The coloring agent is not particularly limited, and examples thereof include tar pigment, titanium oxide, turmeric extract, riboflavin and the like.
The beauty and health composition of the present invention may contain one or more of these colorants, if desired.
結合剤としては、特に限定されず、例えば、エタノール、プロパノール、ポリビニルアルコール、メチルセルロース、エチルセルロース、カルボキシメチルセルロース、ヒドロキシプロピルセルロース、ヒドロキシプロピルメチルセルロース、ゼラチン、デンプン、ブドウ糖、アラビアゴム、リン酸カルシウム、アルギン酸ナトリウム、アルギン酸プロピレングリコールエステルなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上の結合剤を含有してもよい。
The binder is not particularly limited, and examples thereof include ethanol, propanol, polyvinyl alcohol, methylcellulose, ethylcellulose, carboxymethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, gelatin, starch, glucose, gum arabic, calcium phosphate, sodium alginate, and propylene alginate. Glycol esters and the like can be mentioned.
The beauty and health composition of the present invention may optionally contain one or more of these binders.
滑沢剤としては、特に限定されず、例えば、ステアリン酸マグネシウム、ステアリン酸カルシウム、コロイダルシリカ、ショ糖脂肪酸エステル、フマル酸ステアリルナトリウム、タルク、ポリエチレングリコールなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上の滑沢剤を含有してもよい。
The lubricant is not particularly limited, and examples thereof include magnesium stearate, calcium stearate, colloidal silica, sucrose fatty acid ester, sodium stearyl fumarate, talc, and polyethylene glycol.
The beauty and health composition of the present invention may contain one or more of these lubricants, if desired.
界面活性剤としては、特に限定されず、例えば、ラウリル硫酸ナトリウム、ポリソルベート８０、Ｔｗｅｅｎ６０、Ｔｗｅｅｎ８０、ポリオキシエチレン硬化ヒマシ油、モノステアリンサングリセリン、グリセリン脂肪酸エステル、ポリグリセリン脂肪酸エステル、ショ糖脂肪酸エステル、プロピレングリコール、モノステアリン酸ソルビタン、モノラウリン酸ソルビタンなどが挙げられる。
本発明の美容健康用組成物は、必要に応じて、これらの１つ以上の界面活性剤を含有してもよい。
Surfactants are not particularly limited, and examples include sodium lauryl sulfate, polysorbate 80, Tween 60, Tween 80, polyoxyethylene hydrogenated castor oil, monostearin sanglycerin, glycerin fatty acid ester, polyglycerin fatty acid ester, sucrose fatty acid ester, Propylene glycol, sorbitan monostearate, sorbitan monolaurate and the like.
The beauty and health composition of the present invention may contain one or more of these surfactants, if desired.
また、本発明の美容健康用組成物は、医薬品又は飲食品に含まれてもよい。 In addition, the beauty and health composition of the present invention may be included in pharmaceuticals or food and drink.
医薬品に含まれる場合は、特に限定されないが、例えば、薬学的に許容される担体とともに、錠剤、カプセル剤、液剤、粉末剤、ペースト状剤、ゲル状剤などの形態で人体に投与される。 When it is included in pharmaceuticals, it is not particularly limited, but for example, it is administered to the human body in the form of tablets, capsules, liquids, powders, pastes, gels, etc., together with a pharmaceutically acceptable carrier.
飲食品は、飲料品又は食料品を意味し、特に限定されないが、例えば、果汁飲料、清涼飲料、コーヒー、野菜ジュース、茶、コーヒー、シロップ、食酢、味噌、果物、野菜、穀物、肉、乳製品、菓子、麺、ゼリー、栄養補助食品、機能性食品、健康食品などが挙げられる。 Food and drink means beverages or food products, and is not particularly limited, but for example, fruit juice drinks, soft drinks, coffee, vegetable juice, tea, coffee, syrup, vinegar, miso, fruits, vegetables, grains, meat, milk products, confectionery, noodles, jellies, nutritional supplements, functional foods, health foods, etc.
Claims (1)
前記銀ナノ粒子による殺菌効果を高める目的で、前記銀ナノ粒子は、四酸化四銀（Ａｇ４Ｏ４）の膜でコーティングされていることを含み、
経口投与される、
美容健康用組成物。 containing silver nanoparticles and edible silicon,
For the purpose of enhancing the bactericidal effect of the silver nanoparticles, the silver nanoparticles are coated with a film of tetrasilver tetroxide (Ag 4 O 4 ),
administered orally,
Composition for beauty and health.
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