JP7446901B2 - PTP packaging - Google Patents

Description

The present invention relates to a PTP package. The present invention particularly relates to a PTP package having a child-proof function (child-resistant function).

In recent years, press-through pack (hereinafter also referred to as "PTP") packaging has been designed to be difficult to open, with the aim of preventing children (infants) from accidentally opening the package and accidentally ingesting the drug. Such PTP packaging is known as childproof PTP packaging.

Patent Document 1 is a PTP package provided by the applicant. This PTP packaging body consists of a container sheet in which a storage part for accommodating the contents is formed, and a lidding sheet for the storage part, and (1) the lidding sheet is made of a base material containing an Al foil layer. It is a laminate with a peelable cover film, (2) a container sheet is laminated on the base material side of the lid sheet, and (3) the interface between the base material and the cover film is a strong adhesive treated area. , a weak adhesion treated area, and a non-adhesion treated area, (4) a part or all of the accommodating part exists on the weak adhesion treated area, and (5) the package has a perforation for dividing the package. (6) A PTP package in which the cover film in the non-adhesive area is perforated at a position different from the perforation in the package so that the non-adhesive area becomes a gripping margin. When using this PTP package, (i) the cover film and the package can be disposed of together; (ii) the cover film is peeled off when the package is divided at the perforation and two containers are individually packaged. (iii) The cover film can be easily peeled off with the "grip" in the non-adhesive area; (iv) The printed layer is a cover film. It completely follows either the side or the base material side, and exhibits effects such as being able to identify characters, patterns, etc.

Patent No. 4196189

The main object of the present invention is to newly provide a PTP package having a child-proof function (CP function or child-resistant function (CR function)).

The present invention includes the following press-through pack (PTP) package.

Item 1.
A PTP package,
The PTP packaging body has a container sheet in which at least two or more accommodating parts are formed, and a lidding material sheet that covers the container sheet,
The lidding sheet has at least a base material and a cover film that can be peeled off from the base material, and covers the container sheet via the base material,
The container sheet has a folded portion between the at least two storage portions,
The cover film is a PTP package, wherein the cover film has a cut portion that extends in a meandering manner in an uneven shape in substantially the same direction as the folded portion.

Item 2.
2. The PTP package according to item 1, wherein at least a convex tip portion of the cut portion includes a weakly adhesive region and/or a non-adhesive region between the base material and the cover film.

Item 3.
The uneven shape is wavy,
The average height of the unevenness is approximately 1.0 mm to approximately 2.0 mm,
3. The PTP package according to item 1 or 2, wherein the radius R of the arc represented by the convex portion is approximately 1.0 mm to approximately 8.0 mm.

Item 4.
4. The PTP package according to any one of items 1 to 3 above, wherein the folded portion runs longitudinally in the longitudinal direction of the PTP package when the PTP package is rectangular.

Item 5.
5. The PTP package according to any one of items 1 to 4, wherein the container sheet does not have perforations for division.

The PTP packaging body of the present invention has excellent childproof function (or child resistant function). The PTP package of the present invention is also excellent in ease of opening.

FIG. 1 is a diagram showing one embodiment of the PTP package of the present invention. FIG. 1 is a diagram showing one embodiment of the PTP package of the present invention. FIG. 1 is a diagram showing one embodiment of the PTP package of the present invention. FIG. 1 is a diagram showing one embodiment of the PTP package of the present invention. FIG. 2 is a diagram showing a PTP package according to the prior art (Patent Document 1).

The present invention includes the following PTP packaging.

(1) PTP package The PTP package of the present invention is preferably a PTP package with a cover film that accommodates and stores pharmaceuticals (medicines such as tablets and capsules), fragrances, chemicals, confectionery, etc. (Figures 1 to 4). The PTP packaging body of the present invention has excellent childproof function (or child resistant function).

The PTP package disclosed in Patent Document 1 is a PTP package in which the cover film is peeled off and the drug is pushed out from the container side, thereby tearing the base material and removing the drug. In the PTP package of Patent Document 1, for example, for the purpose of adding childproof properties, the cover film may not have a part (knobs part) for picking with fingers, or even if it is provided, it has a structure that makes it difficult to pick the part. If you do so, it may be difficult to remove the cover film when necessary. Also, for example, if the end of the cover film is provided with a tab that is easy to see from the outside in order to make it easier to peel off the cover film, the possibility that even children (infants) can easily open it (possibility of accidental ingestion) can be reduced. Yes.

The PTP package of the present invention improves the PTP package of Patent Document 1, and has (1) childproof properties (prevention of accidental ingestion) that make it difficult to open accidentally if you do not know the opening procedure; (2) If you know the opening procedure, you can easily peel off the cover film when necessary, making it easy to open.

The PTP packaging body of the present invention includes a container sheet in which at least two or more accommodating parts are formed, and a lid sheet that covers the container sheet, and the lid sheet includes at least a base material and the base material. a cover film that can be peeled off from the material, and covers a container sheet through the base material, the container sheet has a folded part between the at least two storage parts, and the container sheet has a folded part between the at least two storage parts, The film has a cut portion that extends in a meandering manner in an uneven shape in substantially the same direction as the bent portion.

In the PTP package of the present invention, preferably, at least the convex tip portion of the notch includes a weak adhesive region and/or a non-adhesive region between the base material and the cover film.

Preferably, in the PTP packaging body of the present invention, the uneven shape is wavy, the average height of the unevenness is approximately 1.0 mm to approximately 2.0 mm, and the radius R of the arc represented by the convex portion is approximately It is 1.0mm to approximately 8.0mm.

Preferably, in the PTP package of the present invention, when the PTP package is rectangular, the folded portion runs longitudinally in the longitudinal direction of the PTP package.

In the PTP package of the present invention, preferably, the container sheet does not have perforations for division.

A PTP package is a package that encloses contents such as medicine. The PTP package includes a container sheet in which at least two or more accommodating portions are formed, and a lidding material sheet that covers the container sheet. The accommodating portion preferably accommodates contents such as medicine.

The lidding material sheet has at least a base material and a cover film that can be peeled off from the base material, and covers the container sheet via the base material. The lidding material sheet is a laminate of the base material and the cover film with a base material in between. The substrate preferably includes aluminum foil.

(2) Container Sheet The PTP package of the present invention includes a container sheet in which at least two or more accommodating portions are formed, and a lidding sheet that covers the container sheet. The container sheet is one of the components of the PTP package, and has a folded part between at least two storage parts (PVC in Figures 1 to 4).

The container sheet is formed with at least two accommodating portions for accommodating contents such as medicines. The accommodating portion is preferably configured to have a concave shape when viewed from the lid sheet side in order to be able to accommodate the medicine.

It is sufficient that the container sheet has two or more accommodating parts. Preferably, when the PTP package has a rectangular shape, a plurality of accommodating parts are provided in the column direction (a direction transverse to the longitudinal direction) and the row direction (a direction transverse to the transverse direction). The accommodating parts are preferably arranged regularly in both the column direction and the row direction, taking into consideration the bendability of the folding part of the lid material sheet.

The material of the container sheet is not particularly limited. The material of the container sheet is preferably appropriately selected from a resin sheet, a metal sheet, or a resin sheet bonded to a metal sheet. The resin sheet is preferably made of, for example, polypropylene, vinyl chloride, or the like.

In the container sheet, a housing part for housing contents such as tablets is formed by hot vacuum forming, hot pressure forming, plug assist molding, etc. using the above-mentioned materials.

The thickness of the container is not particularly limited. The thickness of the container is preferably usually about 50 μm to 100 μm.

Folding section In the PTP packaging container of the present invention, the container sheet has a folding section between at least two storage sections, and the cover film meanders in an uneven shape in substantially the same direction as the folding section. It has a notch that extends from the bottom (bent part in Figures 1 to 3). The container sheet has a folding portion configured to be foldable between two or more storage portions, preferably in a longitudinal or transverse direction.

The structure in which the container sheet has a folding portion is preferably such that the container sheet is provided with creases in advance so that it can be easily folded. Preferably, when the container sheet has a structure in which it can be folded by an adult's hands, it may have a structure in which no crease is provided.

Preferably, when the PTP packaging body is rectangular, the folded portion of the container sheet has a structure that cuts vertically in the longitudinal direction (column direction) (the folded portion in FIGS. 1 and 3), or in the transverse direction (row direction). (the folded part in Figures 2 and 3). Preferably, the structure in which the container sheet has a folded portion is such that, for example, two or more accommodating portions are regularly arranged in both the column direction and the row direction, and the accommodating portions are arranged in a longitudinal direction between the accommodating portions. When the folding device is folded toward the user, the other storage portions are not arranged on an extension line of the bending direction.

More preferably, when the PTP package is rectangular, the folded portion of the container sheet is longitudinally cut in the longitudinal direction of the PTP package.

Perforation for division In the PTP packaging container of the present invention, the container sheet preferably does not have perforations for division. The container sheet has a folded part between at least two or more accommodating parts, and does not have perforations for division, so that the accommodating parts of the container sheet are not separated one by one, and the accommodating parts are separated. Helps prevent accidental ingestion.

(3) Lid Sheet The PTP package of the present invention has a container sheet in which at least two or more accommodating parts are formed, and a lid sheet that covers the container sheet (cover film (protective film) shown in Fig. 4). ) and base material (PTP part)). The lidding material sheet has at least a base material and a cover film that can be peeled off from the base material, and covers the container sheet via the base material. The cover film has a cut portion that extends in a meandering manner in an uneven shape in substantially the same direction as the folded portion.

The lidding material sheet covers the container sheet via the base material (on the opposite side of the cover film) and is laminated. The base material of the lid material sheet preferably has adhesive properties itself and is bonded to the cover film. Preferably, an adhesive is disposed between the base material and the cover film, and the lid material sheet is bonded to the base material and the cover film through the adhesive.

Base material The base material preferably includes, for example, aluminum foil (Al foil) (base material (PTP portion) in FIG. 4).

The Al foil included in the base material is preferably Al foil used in known PTP.

The thickness of the Al foil included in the base material is preferably about 10 μm to 30 μm, and a soft material, semi-hard material, or hard material such as (JIS) 1N30 material, 8021 material, 8079 material is used. When the thickness of the Al foil is 10 μm or more, it has excellent moisture resistance. When the thickness of the Al foil is 30 μm or less, it exhibits a good press-through function (20AL of the base material in Figure 4).

The base material preferably includes a thermal adhesive layer for the purpose of adding adhesion to the container sheet (VC, PVC sheet and heat seal in Figure 4). The thermal adhesive layer is not particularly limited. The thermal adhesive layer is preferably a thermal adhesive layer (thermal adhesive) used in known PTP, such as polypropylene adhesive, vinyl chloride adhesive, vinyl chloride-vinyl acetate copolymer system. Use adhesive, etc.

The coating amount of the thermal adhesive is preferably about 0.5 g/m ² to 15 g/m ² in weight after drying. The heat sealing conditions during the production of the PTP package are preferably usually about 140°C to 260°C and about 1 second to 3 seconds. The cross-sectional shape after sealing is preferably a continuous uneven (jagged) mesh seal.

Cover film The type of cover film is not particularly limited (cover film (protective film portion) in FIG. 4). The cover film is preferably a known resin film, such as a polyethylene film, a polypropylene film, a polyester film, or a polyamide (nylon) film. The cover film is preferably made of a known resin, such as (meth)acrylic resin, polyvinyl chloride resin, polystyrene resin, polyvinylidene chloride resin, saponified ethylene-vinyl acetate copolymer, Resins such as polyvinyl alcohol, polycarbonate resin, polyvinyl acetate resin, and acetal resin are used for the film.

The resin film constituting the cover film is preferably a uniaxially or biaxially stretched resin film, or an unstretched resin film.

The cover film is preferably a resin film such as polyethylene terephthalate (PET) or polypropylene (25PET of the cover film in Figure 4), and a laminate product consisting of a transparent protective layer/Al foil/adhesive layer/PET layer. (cover film OP/12AL/DL/25PET in Figure 4).

The cover film of the lid material sheet can be peeled off from the base material. The base material and the cover film are configured to be releasable, and with this configuration, even if the (peelable) cover film is peeled off, the base material remains laminated on the container sheet. In other words, the base material remains on the container sheet. That is, even if the cover film is peeled off, the contents stored in the container sheet are not immediately exposed (do not jump out), which can effectively prevent children (infants) from accidentally ingesting the drug.

The aluminum foil (Al foil) (12AL of the cover film in Fig. 4) constituting the cover film preferably has a printing layer, a colored layer (solid white of the cover film in Fig. 4), and a primer coat layer (Fig. 4). It is also possible to laminate and interpose a cover film (OP) etc.

The thickness of the cover film is not particularly limited, and is appropriately set depending on the use of the PTP package, the material of the cover film, etc. The thickness of the cover film is preferably about 9 μm to 45 μm in terms of sealing, for example, with a conventional filling machine. When the thickness of the cover film is 9 μm or more, when the container sheet is folded at the bending portion, the tab portion is lifted up favorably and the tab portion is formed. When the thickness of the cover film is 45 μm or less, the rigidity of the cover film does not become too high and it can be bent well.

The cover film is removable from the base material The configuration in which the base material and the cover film are removable is not particularly limited. In a structure in which the base material and the cover film can be peeled off, the base material and the cover film are preferably laminated using an adhesive having low adhesive strength. A dry laminating adhesive is preferably used on the substrate, for example by a dry laminating method (release layer and DL of the cover film in Figure 4).

Cut portion of cover film In the PTP packaging container of the present invention, the container sheet has a folded portion between at least two storage portions, and the cover film has an uneven shape extending in substantially the same direction as the folded portion. It has a notch that extends in a meandering manner (bent part in Figures 1 to 3).

Preferably, when the PTP package is rectangular, the cut portion of the cover film has a structure that cuts vertically in the longitudinal direction (column direction) (the cut portion in FIGS. 1 and 3), or a structure that cuts in the transverse direction (row direction). A cross-sectional structure (notch in Figures 2 and 3) shall be used.

The cut portion may have an uneven shape, and its shape is not particularly limited. The uneven shape of the cut portion is preferably a wave shape, a blade shape formed by repeatedly bending a straight line in a Z-shape, or the like.

More preferably, the uneven shape of the cut portion is wavy. Preferably, the notch has a wavy shape, the average height of the convexity is approximately 1.0 mm to approximately 2.0 mm, and the radius R of the arc represented by the convex portion is approximately 1.0 mm to approximately 2.0 mm. It is 8.0mm.

Preferably, the uneven shape of the cut portion is a blade shape formed by repeatedly bending a straight line in a Z-shape, and the apex (convex portion) has a semicircular shape (R shape) drawing an arc. When the apex (convex part) of the blade shape formed by repeatedly bending a straight line in a Z-shape has a semicircular shape (R shape) drawing an arc, the radius R of the arc represented by the convex part is preferably 0.5 mm. The distance between the uneven shapes is equal to or less than the above distance.

The size of the uneven shape of the cut portion is not particularly limited. The size of the uneven shape of the cut portion is preferably such that the height from the center of the uneven shape to the convex portion is 0.5 mm or more and 4 mm or less.

The interval (pitch, one convex portion) between adjacent concavo-convex shapes of the cut portions is not particularly limited. The interval between adjacent uneven shapes of the cut portion (one convex portion) is preferably 8 mm or more and 20 mm or less.

The uneven shape of the notch preferably does not coincide with the convex part of the notch with respect to the center between the accommodating parts of the container sheet, and is, for example, in the range of 0.5 mm or more and 4 mm or less. , is off.

The cut portion is preferably perforated (through-perforation or cut). The cut portion can preferably be formed by perforating, and instead of perforating, a half cut or the like is used (half cut in FIG. 1). The cut in the cut portion is preferably made by cutting with a blade or cutting with a laser.

In the present invention, in order to make it easier to peel off the cover film, it is particularly desirable to perforate the non-adhesive treated area of the cover film. Depending on the material of the protective layer, it may be difficult to peel off the protective layer only from the non-adhesive portions of the perforations of the package. In this case, by making perforations in the protective layer in advance at positions different from the perforations of the package, when the package is divided at the perforations, only the protective layer is divided at different positions, and the ``Grasping fee''. In this case, the shape of the perforation can be designed such that the perforation of the package has a rectangular wave shape or a sine curve, for example, so that the perforation goes in and out from the left and right (or up and down). This allows both containers to be easily peeled off. The perforations on the container side (package perforations) are preferably in the form of a grid so as to surround two accommodating parts (pocket parts), and are made at corresponding positions on the opposite side of the perforations on the cover film side. Instead of perforations, it is preferable to use so-called half-cuts or the like.

The cutout cover film preferably further includes a cutout in a direction perpendicular to the centerline of the cutout. Preferably, the cutout section and the cutout section are configured to define each storage section of the container sheet. The cutout allows opening only one container.

The cutout portion can preferably be formed by perforating, and instead of perforations, a half cut or the like is used (half cut in FIG. 1). The cuts in the cutout portion are preferably made by cutting with a blade or cutting with a laser.

The weak adhesion region and/or non-adhesion region of the cut portion The cut portion preferably forms a region between the base material and the cover film, and at least the convex tip portion of the cut portion forms a weak adhesion region and/or non-adhesion region. include.

Preferably, the cut portion includes, at least at the tip of the convex shape, a region where the base material and the cover film are weakly bonded or not bonded to each other. When the PTP package is folded along the folded portion of the container sheet, the tip of the uneven convex shape of the notch of the cover film protrudes due to the weakly adhesive region and/or non-adhesive region, and becomes a grip portion. In the PTP packaging container of the present invention, preferably, the interface between the base material and the cover film includes a strong adhesion treated area, a weak adhesion treated area where an adhesive treatment is weaker than the strong adhesion treated area, and an adhesive treated area. By forming the non-adhesive processed area where no adhesive has been applied, the tip of the convex shape of the cut portion protrudes and becomes a knob portion.

The peel strength (adhesive strength) of each region is appropriately set depending on the use, usage conditions, etc. of the PTP package. The peel strength of the strong adhesive treatment area is preferably 2.0 (N/15 mm width) or more. The peel strength of the weak adhesion treated area is preferably 0.5 (N/15 mm width) or more and less than 2.0 (N/15 mm width). The peel strength of the non-adhesive treated area is preferably less than 0.5 (N/15 mm width).

In the PTP package of the present invention, preferably, the non-adhesive treated region becomes a gripping portion (grasping margin), and the region is perforated (through-perforation or cut). Thereby, peeling can be easily performed. The perforation process is preferably performed so as to form a gripping part, for example, into an uneven shape such as a wave shape. The position of the perforation is preferably not limited to the non-adhesive treated area; for example, if the non-adhesive treated area is not provided, the perforation is performed in the weakly adhesive treated area.

The cover film can be peeled off by pinching this knob and pulling it off.

When the cover film is preferably provided with a cut-out portion, the cover film can be peeled off in an area corresponding to one accommodating portion.

(4) Release coat layer The PTP package of the present invention is configured such that the base material and the cover film can be separated.

The embodiment in which the base material and the cover film are configured to be releasable is not particularly limited. In an embodiment in which the base material and the cover film are configured to be removable, preferably, for example, the surface of the base material is provided with an adhesive layer (DL between the cover film and the base material in FIG. 4), and the surface thereof is provided with an adhesive layer (DL between the cover film and the base material in FIG. 4). Furthermore, the structure is such that a release coat layer (release layer of the cover film in FIG. 4) is provided.

The release coating layer is preferably formed using a release coating agent. As the release coating agent, preferably, for example, a known release coating agent such as an acrylic type, a silicone type, a fluorine type, etc. is used.

The release coating layer is preferably laminated via an adhesive layer on the surface of the base material of the lid material sheet facing the cover film, and is coated on the entire surface (so-called solid coating) to maintain a non-adhesive state. becomes. The release coat layer is preferably formed partially (partially coated portion) to impart releasability (easy releasability) depending on the area occupied by the release coat layer.

In the PTP package of the present invention, preferably, the lid material sheet has at least a base material and a cover film that can be peeled off from the base material, and the release coat layer (release layer) allows the lid material sheet to have at least a base material and a cover film that can be peeled off from the base material. At least the convex tip portion of the cut portion includes a weakly bonded region and/or a non-bonded region between the cut portion and the cover film.

The release coat layer is preferably striped so that registration (positioning) is easy and parallel to the longitudinal direction (hereinafter also referred to as "winding direction") of the raw sheet constituting each layer. to form stripes. The direction of the stripes is not particularly limited. The direction of the stripes is preferably perpendicular to the longitudinal direction of the original fabric sheet.

The amount of the release coating agent applied is not particularly limited. The release coating agent is preferably applied in an amount of about 0.3 g/m ² to 10 g/m ² after drying when the entire surface is coated (solid coated area, non-adhesive area). The release coating agent is preferably applied in an amount of approximately 0.1 g/m ² to 3 g/m ² after drying in the partially coated area (weakly bonded area).

The method of forming the release coat layer is not particularly limited. The method for forming the release coat layer preferably includes coating methods such as brush coating, roller coating, and spray coating, and known printing methods such as gravure printing and screen printing.

(5) Adhesive layer The PTP package of the present invention preferably includes an adhesive layer for the purpose of laminating the base material and the cover film (DL between the cover film and the base material in FIG. 4).

The adhesive layer can be formed using a known adhesive. The adhesive layer preferably uses, for example, a polyurethane adhesive, a polyester adhesive, or at least one of the above adhesives.

The amount of adhesive applied is not particularly limited. The adhesive is generally applied in an amount of about 0.5 g/m ² to 15 g/m ² after drying.

(6) Printed layer The PTP package of the present invention preferably further includes a printed layer on the cover sheet (solid white of the cover film in FIG. 4).

The method of forming the printed layer is not particularly limited. The printing layer is preferably formed by a known printing method such as gravure printing, screen printing, or offset printing.

The position where the printed layer is formed is not particularly limited. Preferably, the printed layer may be formed at any location such as the base material or the cover film, and two or more printed layers may be formed.

The content to be printed is not particularly limited. The content to be printed is preferably set appropriately depending on the purpose of the PTP package, the purpose of use, etc. For example, when packaging a medicine, the name of the medicine, precautions, etc. are printed on the printing layer.

(7) Transparent protective layer The PTP package of the present invention preferably further includes a transparent protective layer (overprint layer, OP layer) on the lid sheet (OP of the cover film in FIG. 4).

The transparent protective layer is preferably formed as necessary especially for the purpose of protecting the printed layer. When the printed layer is formed on both the cover film and the base material, preferably a transparent protective layer is provided on both the cover film and the base material for the purpose of protecting each printed layer.

The material forming the transparent protective layer is not particularly limited. The material for forming the transparent protective layer is preferably a material used in known PTP packaging bodies, such as nitrocellulose resin, epoxy resin, or the like.

The coating amount of the material forming the transparent protective layer is not particularly limited. The coating amount of the material forming the transparent protective layer is preferably about 0.5 g/m ² to 5 g/m ² after drying.

(8) Aluminum foil layer (Al foil layer)
In the PTP package of the present invention, the Al foil contained in the lid sheet is not particularly limited (12AL of the cover film and 20AL of the base material in FIG. 4). The Al foil layer is preferably formed on the base material or, if necessary, on the cover film.

The Al foil contained in the lid sheet can preferably be the same Al foil used in known PTP packaging bodies, such as JIS (AA) 1000 series and 8000 series. Use Al foil such as Among Al foils, a hard material (H material) is more preferably used.

The thickness of the Al foil layer is not particularly limited. The thickness of the Al foil layer is preferably generally about 10 μm to 50 μm.

(9) Sealant coat layer In the PTP package of the present invention, preferably, for the purpose of laminating the lid sheet and the container sheet, the outermost surface of at least one of the lid sheet and the container sheet is further coated with a sealant. Layers (Figure 4, base material VC, PVC and heat seal).

The sealant coat layer is not particularly limited. The sealant coat layer is preferably formed of a material similar to that used in known PTP packaging bodies, such as resins such as polypropylene and vinyl chloride-vinyl acetate copolymers.

The thickness of the sealant coat layer is usually about 0.5 g/m ² to 15 g/m ² after drying.

Heat-sealing conditions during packaging production are usually about 140 to 260°C and about 1 to 3 seconds. The cross-sectional shape after sealing may be a continuous uneven (jagged) mesh seal.

(10) Preparation of lid material sheet In the PTP package of the present invention, the lid material preferably includes an anchor coat layer, a thin paper layer, a vapor deposited layer of aluminum, alumina, silica, etc., a primer coat layer, as required. A printing layer, a colored layer, a barcode layer, a key lacquer layer, an overcoat layer, a light shielding layer, etc. are provided.

The method of laminating each layer of the lid material sheet is not particularly limited. The method for laminating each layer of the lidding material sheet is preferably a known method, such as dry lamination using a polyester or polyurethane adhesive, wet lamination, heat lamination, extrusion lamination, gravure printing, Lamination is carried out by application lamination using roll coating, etc. Further, the cover film has a cut portion extending in substantially the same direction as the folded portion of the container sheet while having an uneven shape.

(11) Preparation of PTP package The method for producing a PTP package of the present invention is not particularly limited, and is preferably carried out according to a conventional method for producing a PTP package.

To manufacture the PTP package of the present invention, first, a printing layer is formed on the cover film (PET), and alignment accessories are also printed at the same time to form the printing layer. Next, weak adhesion regions and/or non-adhesion regions (interface portions) are formed. Specifically, the release coat was aligned with the positioning accessory, in other words, in a striped pattern perpendicular to the winding direction of the web (the short direction of the PTP) (so that the release coat was applied in the long direction of the PTP). ) to coat.

Meanwhile, a printing layer is formed on the Al foil. Lines may be provided when forming the printing layer on the Al foil. Next, an OP layer is formed on the printing layer. Thereafter, the release coat and the OP layer are bonded together with an adhesive. In this case, bonding is performed while detecting the alignment line between the two using a line sensor or the like.

Thereafter, the lidding material sheet and the container sheet containing the contents are laminated.

(12) Usefulness of PTP packaging In the PTP packaging of the present invention, when taking out a drug such as a tablet or capsule from a storage part, the container sheet is folded along the folded part and the cover film is peeled off. At this time, among the uneven shapes of the cover film, the tip of the convex shape (weakly bonded area or non-adhesive area) is lifted from the base material to form a grip for peeling. That is, the cover film of the lid sheet is peeled off along the base material, and the base material remains on the container sheet. Then, after peeling off the cover film by picking the knob, the drug is pushed out from the storage section (container), thereby tearing the base material and taking out the drug.

For example, when considering the safety of children (infants), the PTP packaging body of the present invention can be used in cases where the child (infant) does not know the procedure for folding the container sheet, does not teach the procedure, or is unable to properly fold the container sheet. If the cover film is removed, it becomes difficult to peel off the cover film because the knob is not formed. Due to this function, the PTP package of the present invention can (1) prevent children (infants) from accidentally swallowing drugs such as tablets and capsules, thereby achieving childproof properties (preventing accidental ingestion);

In addition to its childproof properties, the PTP packaging body of the present invention has the advantage that, for example, when used by an adult, the container sheet can be folded based on instructions from an instruction manual, a doctor, a pharmacist, etc. It will be easy to peel off the cover film if you understand the procedure for forming the cover film and peeling off the cover film by picking this knob. Due to this function, the PTP package of the present invention can achieve (2) ease of opening, in which the cover film can be easily peeled off when a drug such as a tablet or capsule is needed.

EXAMPLES The present invention will be specifically described below with reference to Examples and Comparative Examples. However, the present invention is not limited to the examples.

<Example 1>
(1) Preparation of cover film (protective film)
As a cover film, a 25 μm thick sheet of aluminum foil (Al foil) (manufactured by Toyo Aluminum Co., Ltd.) (12AL of the protective film in Figure 4) with a thickness of 25 μm was attached to one side of a 12 μm thick, 1N30, glossy, soft aluminum foil (manufactured by Toyo Aluminum Co., Ltd.) (12AL of the protective film in Figure 4). PET film (25PET in Figure 4) (product name "E5100" manufactured by Toyobo) was laminated. The adhesive (DL between 12AL and 25PET in Figure 4) is a two-component curing adhesive for dry lamination, with 10 parts by weight of the product name "LX-500" as the main agent and the product name "KW75" as the curing agent. 1 part by weight (both manufactured by Dainippon Ink and Chemicals) was used. The adhesive was applied by gravure coating at a coating amount of 3 g/m ² after drying. After drying the applied coating film (adhesive layer) at 80°C, the PET film and Al foil were bonded together at 60°C.

Next, a release coat layer (release layer in Figure 4) was laminated on the PET film. As a release coating agent for forming the release coating layer, a liquid agent containing 17% by weight of acrylic resin and 2% by weight of wax in an organic solvent (a mixture of methyl ethyl ketone and ethyl acetate at a weight ratio of 1:1) was used. Application of the release coating agent was performed using a gravure coat (#175 gravure plate with a plate depth of 33 μm). In addition, the Al foil is rectangular, and the release coating agent (forming the release coating layer) is applied solidly in the range of 13 mm width from the center in the longitudinal direction, and in the other area, the release coating agent (forming the release coating layer) is applied in a mesh pattern. The coating was applied so that the area ratio of the film (forming a release coating layer) was 50%. The applied coating film (release coat layer) was dried at 70°C.

Next, a half-cut process was performed by laser cutting from the release coat layer side (half-cut in FIG. 4). As shown in Figure 1, the half-cut pattern consists of a rectangular Al foil, half-cut lines parallel to each other at 16 mm intervals in the transverse direction, and a Z-shaped straight line repeatedly folded back in the longitudinal direction, resulting in a wavy uneven shape. A zigzag half-cut line was created. For the zigzag half-cut line, the radius R of the arc represented by the convex part was 1.0 mm, the height of the convex part from the center line was 1.0 mm, and the interval between adjacent convex parts was 8.0 mm (one convex part 8.0mm).

Next, a solid white layer (solid white in Figure 4) was provided on the other side of the Al foil (12AL of the protective film in Figure 4) by gravure coating. Next, an OP coat layer (OP of the protective film in Figure 4) (overprint layer, transparent protective layer) was laminated on the white solid layer. A nitrocellulose-based OP coating agent was used to form the OP coating layer. The OP coating agent was applied by gravure coating at a coating amount of 1.6 g/m ² after drying. The applied coating film (OP coat layer) was dried at 180°C.

Next, a sealant coat layer (DL between the release layer and OP in FIG. 4) was laminated on the surface of the release coat layer. Maleated polypropylene was used as a sealant coating agent. The sealant coating agent was applied by gravure coating at a coating amount of 3.5 g/m ² after drying. The applied coating film (sealant coat layer) was dried at 200°C.

(2) Preparation of the base material (PTP part) As the base material, one side of a 20 μm thick, 1N30, single gloss, hard aluminum foil (Al foil) (manufactured by Toyo Aluminum Co., Ltd.) (20AL of the base material in Figure 4) Then, an OP coat layer (OP of the base material in Figure 4) (overprint layer, transparent protective layer) was laminated. A nitrocellulose-based OP coating agent was used to form the OP coating layer. The OP coating agent was applied by gravure coating at a coating amount of 1.5 g/m ² after drying. The applied coating film (OP coat layer) was dried at 180°C.

Next, a VC layer (VC in FIG. 4, sealant coat layer) was formed on the other side of the Al foil (20AL of the base material in FIG. 4) by gravure coating.

Next, using an adhesive, the release coat layer side of the cover film (release layer of the protective film in Figure 4) and the OP coat side of the base material (OP of the base material in Figure 4) were laminated to obtain a lidding film. .

(3) Preparation of container (PVC) A accommodating portion was formed into a 250 μm thick PVC film (manufactured by Sumitomo Bakelite Co., Ltd.) (PVC in FIG. 4) as a container sheet by known hot pressure forming. Ten accommodating parts were arranged regularly in the longitudinal direction and two in the lateral direction, and each accommodating part was a circle with a diameter of 9.9 mm and a height of 4.0 mm. No accommodating portion was provided at the center portion of the container sheet in the longitudinal direction, so that the container sheet could be folded, and this was used as the bending portion.

(4) Preparation of PTP packaging body The lid material sheet (cover film and base material) and the container sheet (PVC) are bonded together via a heat seal layer (PVC sheet and heat seal in Figure 4). It was heat-sealed using a sealer to form a 35 mm x 95 mm PTP package (Figures 1 and 4).

(5) Evaluation of PTP packaging
PTP packages were given to 10 adult subjects, and each subject was asked to declare whether they could open the package within 3 minutes and, if they were able to open it, the degree of ease of opening the package.

Five of the 10 adult subjects (subjects A to E) played the role of adults and were informed in advance of how to open the PTP package.

Of the 10 adult subjects, the remaining 5 subjects (subjects F to J) acted as children and did not know how to open this PTP package.

(A) Ease of opening: Evaluation criteria for a test subject (adult role) who was informed of the opening method in advance.The adult role is a test subject who knows in advance how to open the PTP package.

10-point rating: The PTP packaging was declared easy to open by the adult actor and could be opened within 1 minute. There are circumstances in which people know in advance how to open a PTP package, and this "10 point rating" indicates that when people know the opening procedure, it is easy to peel off the cover film when necessary, and the package is easy to open. .

5-point evaluation: A PTP package that an adult role can open within 1 minute or more and within 3 minutes, regardless of the declaration of ease of opening.

1 point rating: The PTP package was opened by the adult role because the adult declared it difficult to open, or the PTP package could not be opened.

(B) CR property: Evaluation criteria for subjects (child actors) who did not know how to open the package (CR property: child resistance property)
The child actor was a subject who did not know how to open a PTP package.

10-point evaluation: The child actor declared that it was difficult to open the package and forced it open by force, or the PTP package could not be opened. There were circumstances in which people did not know how to open the PTP package, and this "10 point rating" was given to childproof properties (preventing accidental ingestion), which makes it difficult to open accidentally if you do not know the opening procedure. represents.

5-point rating: The PTP package was opened by the child actor within 1 minute and within 3 minutes, regardless of the declaration of ease of opening.

1 point rating: A PTP package that the child actor declared easy to open and was able to open it within 30 seconds.

<Example 2>
In Example 2, a PTP package was produced in the same manner as in Example 1, except that the radius R of the arc represented by the convex part of the zigzag half-cut line was changed to 2.0 mm based on Example 1. .

<Example 3>
In Example 3, a PTP package was produced in the same manner as in Example 1, except that the radius R of the arc represented by the convex part of the zigzag half-cut line was changed to 4.0 mm based on Example 1. .

<Example 4>
In Example 4, a PTP package was produced in the same manner as in Example 1, except that the radius R of the arc represented by the convex portion of the zigzag half-cut line was changed to 8.0 mm.

<Example 5>
In Example 5, a PTP package was produced in the same manner as in Example 1, except that the height of the convex portion from the center line of the zigzag half-cut line was changed to 2.0 mm.

<Example 6>
In Example 6, a PTP package was produced in the same manner as in Example 5, except that the radius R of the arc represented by the convex part of the zigzag half-cut line was changed to 2.0 mm, based on Example 5. did.

<Example 7>
In Example 7, a PTP package was produced in the same manner as in Example 5, except that the radius R of the arc represented by the convex part of the zigzag half-cut line was changed to 4.0 mm based on Example 5. did.

<Comparative example 1>
Comparative Example 1 simulates the PTP packaging body of the prior art (Patent Document 1) shown in Fig. 5. Based on Example 1, the half-cut of the cover film is eliminated, and the release coating agent pattern and perforations shown in Fig. 5 are simulated. A PTP package was produced in the same manner as in Example 1, except for the cut pattern.

Opening evaluations were conducted for Examples and Comparative Examples. The results are shown in Table 1.

Discussion of the evaluation results of Comparative Example 1 The PTP packaging of the prior art is not childproof in that it can be opened even when the opening procedure is unknown, even by a child actor, and it can be opened carelessly. (CR property) (accidental ingestion prevention) can be evaluated as not being good.

Discussion of the evaluation results of Examples 1 to 7 The PTP packaging bodies of the present invention (Examples 1 to 7) are easy to open when the opening procedure is known, that is, when the adult role is used, the cover film is easy to peel off when necessary. have sex. The PTP package of the present invention has excellent childproof properties (CR properties) (prevention of accidental ingestion), which makes it difficult for children to open it when they do not know how to open it, and it is difficult to open it carelessly. Be prepared.

In the PTP packaging body of the present invention, for example, as shown in Example 4, the uneven shape is preferably wavy, and the average height of the unevenness is about 1.0 mm to about 2.0 mm, and the above-mentioned If the radius R of the arc represented by the convex part is about 1.0 mm to about 8.0 mm, there is an advantage that it is difficult for children (subjects who did not know how to open the package) to open the package (childproof property). It has the advantage that it is particularly easy to open (easiness of opening) for subjects who have been informed of the opening method in advance.

The PTP packaging of the present invention has (1) childproof properties (prevention of accidental ingestion) that make it difficult to open accidentally when the opening procedure is not known, and (2) when necessary when the opening procedure is known. The cover film is easy to peel off and the package is easy to open.

Claims (5)

A press-through pack packaging body,
The press-through pack packaging body includes a container sheet in which at least two or more accommodating portions are formed, and a lidding sheet that covers the container sheet,
The lidding sheet has at least a base material and a cover film that can be peeled off from the base material, and covers the container sheet via the base material,
The container sheet has a folded portion between the at least two storage portions,
The cover film has a cut portion that extends in a meandering manner in an uneven shape in substantially the same direction as the bent portion,
When the container sheet is folded along the folded portion and the cover film is peeled off, the tip of the convex shape of the uneven shape of the cover film lifts off from the base material to form a peeling part. do,
Press-through pack packaging. 2. The press-through pack package according to claim 1, wherein at least a convex tip portion of the cut portion includes a weakly bonded region and/or a non-bonded region between the base material and the cover film. The uneven shape is wavy,
The average height of the unevenness is 1.0 mm to 2.0 mm ,
3. The press-through pack package according to claim 1, wherein the radius R of the arc represented by the convex portion is 1.0 mm to 8.0 mm . 4. The press-through pack package according to claim 1, wherein when the press-through pack package has a rectangular shape, the folded portion extends longitudinally in the longitudinal direction of the press-through pack package. 5. The press-through pack package according to claim 1, wherein the container sheet does not have perforations for division.