JP7657550B2 - Composition - Google Patents

Description

The present invention relates to a composition.

Skin develops spots, wrinkles, sagging, pigmentation, etc. due to internal factors such as aging and stress, and external factors such as ultraviolet rays and dry air. Many people wish to improve morphological changes such as wrinkles and sagging, as these have a significant impact on the appearance of the skin. Many drugs have been proposed to prevent and improve wrinkles and sagging. Among these, niacinamide is known to be highly safe, and cosmetics containing it are being developed. For example, a skin anti-aging cosmetic product is known that contains nicotinamide, urea, and one or more compounds selected from the group consisting of α-hydroxycarboxylic acid compounds having 2 to 28 carbon atoms (see, for example, Patent Document 1).

On the other hand, tranexamic acid is known to have an anti-inflammatory effect and is sometimes used for the purpose of obtaining a whitening effect. In recent years, tranexamic acid and its derivatives are known to be used as wrinkle-improving agents. For example, a technique is known in which an aminocarboxylic acid derivative having a specific structure and its acid addition salt are used in combination with tranexamic acid and its derivatives to provide a wrinkle-improving composition having a more excellent wrinkle-improving effect (see, for example, Patent Document 2).

Japanese Patent Application Publication No. 10-130135 JP 2019-206483 A

Conventionally used niacinamide and tranexamic acid have excellent moisturizing properties, and when used in combination, a high level of moisturizing effect can be expected, but they can be less convenient to use due to stickiness and other issues. Furthermore, when beauty ingredients other than niacinamide and tranexamic acid, such as plant extracts, are used in formulations, they can sometimes cause a particular stickiness.

Therefore, the objective of the present invention is to develop a composition that has a moisturizing feel but is not sticky and has excellent usability.

In view of this situation, the present inventors conducted extensive research and searched for a material that maintains or further enhances the moisturizing feel of a composition containing niacinamide and tranexamic acid and is non-sticky. The inventors' research led them to discover that by using a specific beauty ingredient that was previously considered sticky in a composition containing niacinamide and tranexamic acid, it is surprisingly possible to obtain a non-sticky composition without compromising the moisturizing feel, and thus completed the present invention.

That is, the present invention relates to a method for producing a pharmaceutical composition comprising the following components (A) to (C):
The present invention relates to a composition comprising at least one cosmetic ingredient selected from the group consisting of (A) tranexamic acid or a salt thereof, (B) niacinamide, and (C) a legume plant or an extract thereof, an Asteraceae plant or an extract thereof, an Apiaceae plant or an extract thereof, a Theaceae plant or an extract thereof, a Myrtaceae plant or an extract thereof, a Citrus plant or an extract thereof, a Ranunculaceae plant or an extract thereof, a Lamiaceae plant or an extract thereof, an Oleaceae plant or an extract thereof, royal jelly extract, honey, sodium metabisulfite, and Cordyceps sinensis extract.

The present invention also relates to a composition as described above, in which the component (C) is at least one selected from the group consisting of a plant of the genus Sophora (Leguminosa) or an extract thereof, a plant of the genus Glycyrrhiza (Leguminosa) or an extract thereof, a plant of the genus Lacertilia (Asteraceae) or an extract thereof, a plant of the genus Celastrus (Asteraceae) or an extract thereof, a plant of the genus Yarrow (Asteraceae) or an extract thereof, a plant of the genus Daucus (Daucus carota) or an extract thereof, a plant of the genus Camellia (Theaceae) or an extract thereof, a plant of the genus Aloe (Myrtaceae) or an extract thereof, a plant of the genus Eucalyptus (Myrtaceae) or an extract thereof, a plant of the genus Citrus (Rutunculaceae) or an extract thereof, a plant of the genus Coptis (Ranunculaceae) or an extract thereof, a plant of the genus Rosemary (Lamiaceae) or an extract thereof, a plant of the genus Olea (Oleaceae) or an extract thereof, royal jelly extract, honey, sodium metabisulfite, and cordyceps sinensis extract.

The present invention also relates to the composition described above, in which the component (C) is at least one selected from the group consisting of a plant of the genus Sophora (Leguminosa) or an extract thereof, a plant of the genus Glycyrrhiza (Leguminosa) or an extract thereof, a plant of the genus Lacertilia (Asteraceae) or an extract thereof, a plant of the genus Celastrus (Asteraceae) or an extract thereof, a plant of the genus Yarrow (Asteraceae) or an extract thereof, a plant of the genus Daucus ... Camellia (Theaceae) or an extract thereof, a plant of the genus Aloe (Myrtaceae) or an extract thereof, a plant of the genus Eucalyptus (Myrtaceae) or an extract thereof, a plant of the genus Citrus (Rutaceae) or an extract thereof, a plant of the genus Coptis (Ranunculaceae) or an extract thereof, a plant of the genus Rosemary (Lamiaceae) or an extract thereof, and a plant of the genus Olea (Oleaceae) or an extract thereof.

The present invention also relates to the composition described above, in which the component (C) is at least one selected from the group consisting of royal jelly extract, honey, sodium pyrosulfite, and cordyceps sinensis extract.

The present invention also relates to the composition described above, in which the content of component (C) in the composition is 0.0001 to 0.01 mass %.

The present invention also relates to the composition described above, in which the mass ratio of the components (A) and (B) is (A)/(B) = 0.01 to 20.

The present invention also relates to the composition described above, in which the mass ratio of the components (B) and (C) is (B)/(C) = 10 to 10,000.

The present invention further relates to the composition described above, which contains component (D) a polyhydric alcohol having 5 to 12 carbon atoms.

The present invention also relates to the composition described above, in which the component (D) is at least one polyhydric alcohol selected from the group consisting of dipropylene glycol, tripropylene glycol, 1,2-pentanediol, 1,2-hexanediol, and 1,2-octanediol.

The present invention also relates to a skin preparation or cosmetic that contains the above-described composition.

The present invention further relates to a stickiness improving agent in a composition containing component (A) tranexamic acid or a salt thereof and component (B) niacinamide, comprising component (C) at least one beauty ingredient selected from the group consisting of a legume plant or an extract thereof, a Asteraceae plant or an extract thereof, a Umbelliferae plant or an extract thereof, a Theaceae plant or an extract thereof, a Xanthomonas plant or an extract thereof, a Myrtaceae plant or an extract thereof, a Citrus plant or an extract thereof, a Ranunculaceae plant or an extract thereof, a Lamiaceae plant or an extract thereof, an Oleaceae plant or an extract thereof, royal jelly extract, honey, sodium metabisulfite, and cordyceps sinensis extract.

The present invention further relates to a method for improving stickiness in a composition containing component (A) tranexamic acid or a salt thereof and component (B) niacinamide, using component (C) a cosmetic ingredient which is at least one selected from the group consisting of a legume plant or an extract thereof, a Asteraceae plant or an extract thereof, a Umbelliferae plant or an extract thereof, a Theaceae plant or an extract thereof, a Xanthomonas plant or an extract thereof, a Myrtaceae plant or an extract thereof, a Citrus plant or an extract thereof, a Ranunculaceae plant or an extract thereof, a Lamiaceae plant or an extract thereof, an Oleaceae plant or an extract thereof, royal jelly extract, honey, sodium metabisulfite, and Cordyceps sinensis extract.

The present invention provides a composition that provides a moisturizing feeling and lasts a long time, but is not sticky.

The present invention will be described in detail below. In this specification, "~" means a range including the numerical values before and after it.

Component (A) tranexamic acid or a salt thereof in the present invention is a type of amino acid with the chemical name trans-4-(aminomethyl)cyclohexane-1-carboxylic acid. In the present invention, it can be used in the form of a salt, and can be a salt of an inorganic base such as a sodium salt or potassium salt, or a salt of an organic base such as triethanolamine or lysine.

The content of component (A) in the present invention is not particularly limited, but the lower limit is preferably 0.01% by mass (hereinafter simply abbreviated as "%") or more, more preferably 0.1% or more, and even more preferably 1% or more. The upper limit is preferably 10% or less, more preferably 7% or less, and even more preferably 5% or less. This range is more preferable because it provides better moisturizing feeling and non-stickiness.

Component (B) of the present invention, niacinamide (also known as nicotinamide), is also known as vitamin B3, and is a coenzyme deeply involved in various biochemical reactions in the body, such as energy metabolism and oxidation-reduction. It is said to have the effect of keeping the skin and mucous membranes normal and promoting blood flow, and it is known that a deficiency of niacinamide can cause symptoms such as "pellagra (dermatitis, gastrointestinal disorders, nerve disorders, etc.)." Niacinamide is also an ingredient that is incorporated into cosmetics and topical skin preparations in the hope of improving the skin, as it is water-soluble; stable against heat, acid, alkali, and light; and highly safe.

The niacinamide used in the present invention may be produced using known production methods, and is also available as a raw material for foods, cosmetics, pharmaceuticals, etc., or as a chemical product or reagent.

The content of component (B) in the present invention is not particularly limited, but the lower limit is preferably 0.01% or more, more preferably 0.1% or more, and even more preferably 1% or more. The upper limit is preferably 10% or less, more preferably 7% or less, and even more preferably 5% or less. This range is more preferable because it provides better moisturizing feeling and non-stickiness.

In the present invention, the composition is obtained by appropriately containing the components (A) and (B), but it is more preferable to specify the mass ratio of the components contained, since this provides a better moisturizing feeling and non-stickiness. Such a mass ratio is not particularly limited, and the lower limit of the mass ratio (A)/(B) of the components (A) and (B) is preferably 0.01 or more, more preferably 0.05 or more, and even more preferably 0.1 or more. The upper limit is preferably 20 or less, more preferably 15 or less, and even more preferably 10 or less.

Component (C) in the present invention is at least one or more cosmetic ingredients selected from the group consisting of legumes or extracts thereof, Asteraceae plants or extracts thereof, Umbelliferae plants or extracts thereof, Theaceae plants or extracts thereof, Miscanthus plants or extracts thereof, Myrtaceae plants or extracts thereof, Rutaceae plants or extracts thereof, Ranunculaceae plants or extracts thereof, Lamiaceae plants or extracts thereof, Oleaceae plants or extracts thereof, royal jelly extract, honey, sodium metabisulfite, and cordyceps sinensis extract. Details are described below, but the plant or extract thereof includes the plant or its closely related species.

The component (C) of the present invention, a legume plant or an extract thereof, is not particularly limited and may be used as long as it is a plant or an extract thereof belonging to the family Fabaceae (Fabaceae). For example, a plant of the genus Sophora or an extract thereof, a plant of the genus Pisum or an extract thereof, a plant of the genus Lupinus or an extract thereof, a plant of the genus Pueraria or an extract thereof, a plant of the genus Glycyrrhiza or an extract thereof, etc. can be mentioned. An example of a plant of the genus Sophora is Sophora flavescens, etc. An example of a plant of the genus Pisum is Pisum sativum L., etc. An example of a plant of the genus Lupin is Lupinus albus, etc. Examples of plants of the genus Pueraria include Pueraria montana var. lobata. Examples of plants of the genus Licorice include Glycyrrhiza glabra. Among these, from the viewpoint of moisturizing feeling and non-stickiness, plants of the genus Sophora or extracts thereof, and plants of the genus Licorice or extracts thereof are preferred. In particular, the use of components (A) tranexamic acid or a salt thereof, and (B) niacinamide in combination with an extract of Sophora flavescens of the genus Sophora and/or an extract of Glycyrrhiza glabra of the genus Licorice of the genus Licorice of the genus Fabaceae is more preferred because it provides a moisturizing feeling, its duration, and non-stickiness.

In the present invention, the component (C) Asteraceae plant or extract thereof is not particularly limited and may be any plant or extract thereof belonging to the Asteraceae family (Asteraceae). For example, Arnica genus (also known as Arnica genus) plant or extract thereof, Matricaria genus plant or extract thereof, Achillea genus plant or extract thereof, Arctium genus plant or extract thereof, Calendula genus plant or extract thereof, Centaurea genus plant or extract thereof, etc. Examples of plants of the Arnica genus include Arnica unalascensis var. tschonoskyi, etc. Examples of plants of the Matricaria genus include Matricaria recutita, etc. Examples of plants belonging to the genus Yarrow include Achillea millefolium. Examples of plants belonging to the genus Burdock include Arctium lappa L. Examples of plants belonging to the genus Calendula include Calendula officinalis. Examples of plants belonging to the genus Centaurea include Centaurea cyanus. Among these, from the viewpoint of moisturizing feeling and non-stickiness, plants belonging to the genus Arnica (also known as Arnica) or extracts thereof, plants belonging to the genus Matricaria or extracts thereof, and plants belonging to the genus Achillea or extracts thereof are preferred. In particular, it is more preferable to use the components (A) tranexamic acid or a salt thereof and (B) niacinamide in combination with one or more selected from the group consisting of an extract of Arnica unalascensis var. tschonoskyi (Asteraceae), an extract of Matricaria recutita (Asteraceae), and Achillea millefolium (Asteraceae), as this provides a superior moisturizing sensation, lasts longer, and is non-sticky.

The component (C) of the present invention, a plant of the Apiaceae family or an extract thereof, can be used without any particular limitation as long as it is a plant of the Apiaceae family or an extract thereof. For example, a plant of the Centella genus or an extract thereof, a plant of the Angelica genus or an extract thereof, a plant of the Daucus genus or an extract thereof, etc. can be mentioned. Examples of plants of the Centella genus include Centella asiatica, etc. Examples of plants of the Angelica genus include Angelica keiskei, etc. Examples of plants of the Daucus genus include carrot (Daucus carota subsp. sativus), etc. Among these, a plant of the Daucus genus or an extract thereof is preferred from the viewpoints of moisturizing feeling and non-stickiness. In particular, it is more preferable to use a combination of the components (A) tranexamic acid or a salt thereof and (B) niacinamide with an extract of Daucus carota subsp. sativus, which belongs to the Apiaceae family, since this combination provides a superior moisturizing effect, lasts longer, and is non-sticky.

In the present invention, the component (C) of the Theaceae plant or its extract is not particularly limited and may be any plant or extract belonging to the Theaceae family. For example, Camellia plants or extracts thereof may be mentioned. Camellia plants include Camellia japonica and Camellia sinensis. Among these, Camellia plants or extracts thereof are preferred from the viewpoints of moisturizing feeling and non-stickiness. In particular, it is more preferable to use a combination of the components (A) tranexamic acid or a salt thereof and (B) niacinamide with an extract of Camellia japonica (Theaceae family) and/or Camellia sinensis (Theaceae family) in order to obtain a moisturizing effect that lasts longer and is non-sticky.

The component (C) Xanthorrhoeaceae plant or extract thereof in the present invention is not particularly limited and may be any plant or extract thereof belonging to the Xanthorrhoeaceae family (also known as the Daylily family). For example, Aloe genus plants or extracts thereof, Hemerocallis genus plants or extracts thereof, etc. are included. Examples of Aloe genus plants include Aloe vera, etc. Examples of Hemerocallis genus plants include Hemerocallis fulva var. fulva, etc. Among these, Aloe genus plants or extracts thereof are preferred from the viewpoints of moisturizing feeling and non-stickiness. In particular, it is more preferable to use a combination of the components (A) tranexamic acid or a salt thereof and (B) niacinamide with an extract of Aloe (Aloe) of the Xanthomoniaceae family, as this provides excellent moisturizing effect, lasts longer, and is non-sticky.

In the present invention, the component (C) Myrtaceae plant or extract thereof is not particularly limited and may be any plant or extract thereof belonging to the Myrtaceae family, such as Eucalyptus plants or extracts thereof, Psidium plants or extracts thereof, and Syzygium plants or extracts thereof.
Examples of Eucalyptus plants include Eucalyptus. Examples of Psidium guajava L. plants include Guava. Examples of Myrtaceae plants include Syzygium aromaticum. Among these, Eucalyptus plants or their extracts are preferred from the viewpoint of moisturizing feeling and non-stickiness. In particular, it is more preferred to use the component (A) tranexamic acid or its salt, and (B) niacinamide in combination with an extract of Eucalyptus of the Myrtaceae family, since it provides excellent moisturizing feeling, its duration, and non-stickiness.

In the present invention, the component (C) Rutaceae plant or extract thereof can be used without any particular limitation as long as it is a plant or extract thereof belonging to the Rutaceae family. For example, Citrus plants or extracts thereof, Phellodendron plants or extracts thereof, etc. are included. Citrus plants include Citrus unshiu, Citrus junos, and Citrus limon. Phellodendron plants include Phellodendron amurensis. Among these, Citrus plants or extracts thereof are preferred from the viewpoints of moisturizing feeling and non-stickiness. In particular, it is more preferable to use components (A) tranexamic acid or a salt thereof and (B) niacinamide in combination with one or more selected from the group consisting of extracts of Citrus unshiu (Rutaceae), Citrus junos (Rutaceae), and Citrus limon (Rutaceae), as this provides a superior moisturizing sensation, lasts longer, and is non-sticky.

In the present invention, the component (C) Ranunculaceae plant or extract thereof is not particularly limited as long as it is a plant belonging to the Ranunculaceae family or an extract thereof, and examples thereof include Coptis plants and extracts thereof.
Examples of Coptis genus plants include Coptis japonica. Among these, Coptis genus plants or their extracts are preferred from the viewpoint of moisturizing feeling and non-stickiness. In particular, by combining the component (A) tranexamic acid or its salt and (B) niacinamide with the extract of Coptis japonica of the Ranunculaceae family, it is more preferred because it provides excellent moisturizing feeling and its duration, as well as non-stickiness.

The component (C) Lamiaceae plant or extract thereof in the present invention is not particularly limited and may be used as long as it is a plant or extract thereof belonging to the Lamiaceae family (Lamiaceae). For example, Perilla plants or extracts thereof, Lavandula plants or extracts thereof, Mentha plants or extracts thereof, Salvia plants or extracts thereof, Rosmarinus plants or extracts thereof, Thymus plants or extracts thereof, etc. are included. Perilla plants include Perilla frutescens var. crispa, etc. Lavandula plants include Lavender, etc. Mentha plants include Mint, etc. Examples of plants belonging to the genus Salvia include sage (Salvia officinalis), etc. Examples of plants belonging to the genus Rosmarinus include rosemary (Rosmarinus officinalis L.), etc. Examples of plants belonging to the genus Thymus include thyme (Thymus L.), etc. Among these, from the viewpoints of moisturizing feeling and non-stickiness, plants belonging to the genus Rosmarinus or extracts thereof are preferred. In particular, it is more preferable to use the components (A) tranexamic acid or a salt thereof and (B) niacinamide in combination with one or more selected from the group consisting of an extract of rosemary (Rosmarinus officinalis L.) of the Lamiaceae family, lavandula (Lavandula angustifolia) of the Lamiaceae family, sage (Salvia officinalis) of the Lamiaceae family, and thyme (Thymus L.) of the Lamiaceae family, since this provides a superior moisturizing sensation, its duration, and a lack of stickiness.

In the present invention, the component (C) Oleaceae plant or extract thereof can be used without any particular limitation as long as it is a plant or extract thereof belonging to the Oleaceae family. For example, Olea plants or extracts thereof, Osmanthus plants or extracts thereof, etc. can be mentioned. Examples of Olea plants include olive (Olea europaea) and the like. Examples of Osmanthus plants include sweet osmanthus (Osmanthus fragrans var. aurantiacus) and the like. Among these, Olea plants or extracts thereof are preferred from the viewpoint of moisturizing feeling and non-stickiness. In particular, it is more preferable to use the component (A) tranexamic acid or a salt thereof, and (B) niacinamide in combination with an extract of Olea europaea, which belongs to the Oleaceae family, in order to provide a more excellent moisturizing feeling, its duration, and non-stickiness.

The plant in the present invention may be used as it is, but is preferably made into an extract from the viewpoint of enhancing the effect of the present invention. The part to be extracted is not particularly limited, and flowers, leaves, stems, roots, seeds, fruits, seed coats, etc. can be used. The part to be extracted can be selected appropriately depending on the plant, and is not particularly limited. For example, the roots of a legume plant or an extract thereof are preferable, the flowers of a Asteraceae plant or an extract thereof are preferable, the roots of a Umbelliferae plant or an extract thereof are preferable, the seeds or leaves of a Theaceae plant or an extract thereof are preferable, the leaves or flowers of a Myrtaceae plant or an extract thereof are preferable, the fruits or peels of a Rutaceae plant or an extract thereof are preferable, the roots or stems of a Ranunculaceae plant or an extract thereof are preferable, the leaves or flowers of a Lamiaceae plant or an extract thereof are preferable, and the fruits of an Oleaceae plant or an extract thereof are preferable.

The plant extraction solvent in the present invention is not particularly limited, and examples thereof include water, organic solvents, etc., from which one or more can be selected. In addition, carbon dioxide or water in a supercritical state can also be used.

The organic solvent may be one or more selected from the group consisting of alcohols, ketones such as acetone, ethers such as ethyl ether, esters such as ethyl acetate, and hydrocarbons such as hexane and benzene.

Examples of the alcohols include lower monohydric alcohols (e.g., methanol, ethanol, etc.); liquid polyhydric alcohols (e.g., 1,3-butylene glycol, propylene glycol, glycerin, etc.). The alcohols are preferably monohydric alcohols and dihydric alcohols, and the number of carbon atoms of the alcohols is preferably about 1 to 5.

Of the extraction solvents, water and/or alcohols (preferably having 1 to 4 carbon atoms) are preferred. The alcohols are preferably one or more selected from methanol, ethanol, propylene glycol, and 1,3-butylene glycol. Of these extraction solvents, more preferred are mixtures of one or more selected from water, ethanol, and 1,3-butylene glycol, more preferably water, ethanol, 1,3-butylene glycol, an ethanol-water mixture, or a 1,3-butylene glycol-water mixture, and even more preferably a 1,3-butylene glycol-water mixture. In the case of an alcohol aqueous solution, the alcohol concentration (V/V) is preferably 0 to 100% by volume, more preferably 20 to 80% by volume.

The royal jelly extract, component (C) of the present invention, is a jelly-like substance obtained by mixing secretions from the hypopharyngeal gland and mandibular gland of worker honeybees. Royal jelly extract is known to have effects such as nutritional tonic, anti-aging, and growth promotion.

Honey is made by bees sucking nectar from plant flowers, breaking it down with enzymes secreted from their salivary glands, and concentrating it. Nectar for honey can be selected from a variety of plants, including plum, mandarin orange, cherry blossom, and manuka. The honey used in the present invention is not particularly limited, but manuka honey is preferred from the viewpoint of moisturizing properties.

Sodium pyrosulfite can also be produced by the dehydration of sodium bisulfite or by adding sulfur dioxide to sodium sulfite. Sodium pyrosulfite has reducing properties and is used as a food bleach and an antioxidant in wine.

Cordyceps sinensis extract is an extract of the fruiting body of Cordyceps sinensis, which parasitizes the larvae of insects such as those of the Pterygota moth family, forms a sclerotium inside the body, and is formed on the body surface of the host insect or its larvae in the summer.

The content of component (C) in the present invention is not particularly limited, but the lower limit, calculated as solid content, is preferably 0.0001% or more, more preferably 0.0005% or more, and even more preferably 0.001% or more. The upper limit is preferably 0.01% or less, more preferably 0.007% or less, and even more preferably 0.005% or less. This range is more preferable because it provides better moisturizing feeling and non-stickiness.

In the present invention, the composition is obtained by appropriately containing the components (B) and (C), but it is more preferable to specify the mass ratio of the components contained, since this provides a better moisturizing feeling and non-stickiness. Such a mass ratio is not particularly limited, and the lower limit of the mass ratio (B)/(C) of the components (B) and (C) is preferably 10 or more, more preferably 50 or more, and even more preferably 100 or more. The upper limit is preferably 10,000 or less, more preferably 5,000 or less, and even more preferably 1,000 or less.

In the present invention, the composition is obtained by appropriately containing the components (A) and (C), but it is more preferable to specify the mass ratio of the components contained, since this provides a better moisturizing feeling and non-stickiness. Such a mass ratio is not particularly limited, and the lower limit of the mass ratio (A)/(C) of the components (A) and (C) is preferably 10 or more, more preferably 50 or more, and even more preferably 100 or more. The upper limit is preferably 10,000 or less, more preferably 5,000 or less, and even more preferably 2,000 or less.

In the present invention, the composition is obtained by appropriately containing the components (A), (B) and (C), but it is preferable to specify the mass ratio of the components because a higher effect can be expected. Such mass ratio is not particularly limited, and the lower limit of the total amount of components (A) and (B) to the mass ratio of component (C) [(A)+(B)]/(C) is preferably 100 or more, more preferably 500 or more, and even more preferably 1000 or more. The upper limit is preferably 12000 or less, more preferably 10000 or less, and even more preferably 5000 or less. This range is more preferable because it provides a better moisturizing feeling and less stickiness.

The present invention may further contain component (D) a polyhydric alcohol having 5 to 12 carbon atoms. The polyhydric alcohol of component (D) in the present invention is not particularly limited as long as it has 5 to 12 carbon atoms, and the lower limit of the carbon number is preferably 5 or more, preferably 6 or more, and even more preferably 7 or more. The upper limit of the carbon number is preferably 12 or less, preferably 10 or less, and even more preferably 9 or less. This range is more preferable because it provides better moisturizing feeling and non-stickiness. Examples of such polyhydric alcohols include dipropylene glycol, tripropylene glycol, diglycerin, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, and 1,2-decanediol, and one or more of these may be used in combination. Among these, at least one selected from the group consisting of dipropylene glycol, tripropylene glycol, 1,2-pentanediol, 1,2-hexanediol, and 1,2-octanediol is preferred, at least one selected from the group consisting of dipropylene glycol, tripropylene glycol, and 1,2-pentanediol is more preferred, and dipropylene glycol and/or tripropylene glycol is even more preferred.

The content of component (D) in the present invention is not particularly limited, but the lower limit is preferably 0.1% or more, more preferably 1% or more, and even more preferably 3% or more. The upper limit is preferably 50% or less, more preferably 30% or less, and even more preferably 15% or less. This range is more preferable because it provides better moisturizing feeling and less stickiness.

The present invention can further contain an aqueous component other than component (D) as component (E). The aqueous component other than component (D) means water or a mixture of water and a component soluble in water. Examples include lower alcohols such as ethyl alcohol and isopropyl alcohol. The content of the aqueous component in the present invention is not particularly limited, and the lower limit is preferably 10% or more, more preferably 30% or more, and even more preferably 50% or more. The upper limit is preferably 90% or less, more preferably 80% or less, and even more preferably 70% or less. This range is more preferable because it provides a better moisturizing feeling and its duration, as well as a better lack of stickiness.

In particular, among the aqueous components, it is more preferable to contain a compound containing one or more structural units selected from the group consisting of polyoxyethylene units (hereinafter sometimes abbreviated as EO units), polypropylene units (hereinafter sometimes abbreviated as PO units), and polyoxybutylene units (hereinafter sometimes abbreviated as BO units) because this provides a better sustained moisturizing feeling. Such compounds are ethers in which EO units, PO units, and BO units are randomly or block-copolymerized with alcohol. The number of carbon atoms in the alcohol is not particularly limited, but preferably has 1 to 3 carbon atoms. The alcohol is also not particularly limited, but may be any of monohydric to trihydric alcohols, more preferably trihydric alcohols, and even more preferably glycerin. Examples of such compounds include polyoxypropylene butyl ether (3PO), polyoxyethylene polyoxypropylene butyl ether (10EO) (7PO), polyoxyethylene polyoxypropylene dimethyl ether (14EO) (7PO), polyoxybutylene polyoxyethylene polyoxypropylene glyceryl ether (3BO) (8EO) (5PO), etc. In the present invention, the content of the compound containing one or more structural units selected from the group consisting of EO units, PO units, and BO units is not particularly limited, but the lower limit is preferably 0.001% or more, more preferably 0.005% or more, and even more preferably 0.01% or more. The upper limit is preferably 5% or less, more preferably 3% or less, and even more preferably 1% or less. This range is more preferable because it provides a better sustained moisturizing feeling.

The present invention may further contain component (F), a film-forming agent. The film-forming agent in the present invention is a substance that forms a film when applied. The film-forming agent in the present invention has the effect of keeping components (A) and (B) in place for a long time, thereby further enhancing the duration of the moisturizing sensation. There are no particular limitations on such film-forming agents, and various types can be used.

For example, water-soluble film-forming agents, emulsion polymer type film-forming agents, oil-based film-forming agents, etc. can be mentioned. More specifically, water-soluble film-forming agents include polyvinylpyrrolidone, polyvinyl alcohol, etc. Furthermore, emulsion polymer type film-forming agents include copolymers containing alkyl acrylate, ethylenic polymers, and vinylpyrrolidone or vinyl alcohol as monomer units, etc. For example, (acrylates/VP) copolymer, (styrene/VP) copolymer, (ethylene/VA) copolymer, (acrylates/VA) copolymer, (VP/VA) copolymer, etc. can be mentioned. Furthermore, oil-based film-forming agents include silicone-based resins such as trimethylsiloxysilicate, polymethylsilsesquioxane, and acrylic-modified silicone, rosin-modified phenolic resin, rosin acid-based resins such as rosin ester, etc. can be mentioned. Among these, water-soluble film-forming agents are preferred from the viewpoint of sustained moisturizing feeling.

In addition to the above-mentioned components, the composition of the present invention may contain optional components within the scope of not impairing the effects of the present invention. For example, the composition may contain powders, water-soluble polymers, colorants, preservatives, antibacterial agents, UV absorbers, fragrances, antioxidants, pH adjusters, chelating agents, cosmetic ingredients other than components (A) to (C), etc.

The composition of the present invention can be produced by any known mixing method without any particular limitations. Examples include dispersion mixing, solubilization, and high-pressure emulsification.

The present invention provides a composition containing component (A) tranexamic acid or a salt thereof and component (B) niacinamide, and further containing component (C) at least one beauty ingredient selected from the group consisting of a legume plant or an extract thereof, a Asteraceae plant or an extract thereof, a Umbelliferae plant or an extract thereof, a Theaceae plant or an extract thereof, a Xanthomonas plant or an extract thereof, a Myrtaceae plant or an extract thereof, a Citrus plant or an extract thereof, a Ranunculaceae plant or an extract thereof, a Lamiaceae plant or an extract thereof, an Oleaceae plant or an extract thereof, royal jelly extract, honey, sodium metabisulfite, and cordyceps sinensis extract, thereby providing a stickiness improving agent for the composition. The preferred components and contents of components (A) to (C) of the stickiness improving agent of the present invention, the mass ratios of components (A) to (C), and the like are the same as those of the above composition.

The present invention also provides a method for improving stickiness of a composition containing component (A) tranexamic acid or a salt thereof and component (B) niacinamide, by adding component (C) at least one beauty ingredient selected from the group consisting of a legume plant or an extract thereof, a Asteraceae plant or an extract thereof, a Umbelliferae plant or an extract thereof, a Theaceae plant or an extract thereof, a Xanthomonas plant or an extract thereof, a Myrtaceae plant or an extract thereof, a Citrus plant or an extract thereof, a Ranunculaceae plant or an extract thereof, a Lamiaceae plant or an extract thereof, an Oleaceae plant or an extract thereof, royal jelly extract, honey, sodium metabisulfite, and cordyceps sinensis extract. The preferred components and contents of components (A) to (C) in the method for improving stickiness of the present invention, and the mass ratios of components (A) to (C) are the same as those in the above composition.

The formulation of the composition of the present invention is not particularly limited, and any of the following formulations can be used for washing: aqueous solution, oil-in-water type, water-in-oil type, and powder. Aqueous solution and oil-in-water type are preferred. The properties are also not particularly limited, and the composition can be in various formulations such as liquid, gel, paste, cream, and solid.

The composition of the present invention can be used, for example, as cosmetics, topical skin preparations, medicines, foods, etc.

The composition of the present invention can be used as a cosmetic. Examples of the cosmetic include skin care cosmetics such as lotion, milky lotion, cream, eye cream, beauty essence, massage product, pack product, hand cream, body milk, body cream, hair styling product, and sunscreen cosmetic; hair cosmetics such as shampoo, rinse, and hair cream; cleansing cosmetics such as body soap, hand soap, face wash, and cleansing product; and makeup cosmetics such as lipstick, powder foundation, liquid foundation, cream foundation, concealer, face powder, makeup base, blusher, eye shadow, mascara, eyeliner, and eyebrow. Methods of use include using hands, cotton, puffs, etc., applying to nonwoven fabric, spraying from a spray container, etc.

The composition of the present invention can also be used as a skin external preparation. Examples of the composition include external liquid preparations, external gel preparations, cream preparations, ointments, liniments, lotions, poultices, plasters, sprays, and aerosol preparations. The method of use can be the same as that of the above-mentioned cosmetics.

The composition of the present invention can also be used as a food. For example, it can be used as a nutritional supplement, a health supplement, a functional health food, a food for specified health uses, a supplement, etc. More specifically,
Examples include candy, yogurt, soup, fruit juice, vegetable juice, soft drinks, etc.

The present invention will be described in more detail below by way of examples, but the present invention is not limited to these in any way.
Example 1 (Products 1-14 of the present invention), Comparative Examples (Comparative Products 1-4): Cosmetic compositions The compositions shown in Table 1 were prepared by the manufacturing method described below, and evaluated and judged according to the evaluation methods and judgment criteria shown below, and the results are also shown in Table 1. The extracts and fruit juices listed in the tables of this example refer to values converted into solid content concentrations.

(Production method)
A: Mix ingredients (1) to (12) uniformly and dissolve.
B: Add ingredients (13) and (14) to A and mix uniformly.
C: The mixture was filled into a container to obtain a cosmetic composition.

(Evaluation items)
A. Moisturizing feeling B. Sustained moisturizing feeling C. Non-sticky feeling

(Evaluation Method)
Six expert panelists (women in their 30s to 50s) who were trained in the sensory evaluation of cosmetics and capable of evaluation according to certain standards were selected. Each sample was applied to the area around the cheeks, and after blending, the panelists were asked to evaluate (a) whether they felt moisturizing (answered "good" if they felt moisturizing, and "bad" if they did not), (b) whether the moisturizing sensation continued even after several hours (answered "good" if they felt moisturizing three hours after application, and "bad" if they did not), and (c) whether they felt sticky (answered "good" if they felt sticky, and "bad" if they did not). The results were reported and judged according to the following criteria.

(Evaluation based on certain standards)
Six expert panel members undergo sensory evaluation of cosmetics. In order to confirm that the evaluation can be performed according to a consistent standard, the following three types of samples were prepared, and 5 g of each sample was applied to the skin (forearm) of the expert panel members, and the degree of stickiness and moisturizing sensation was checked.

(Confirmation sample)
Sample a: Glycerin Sample b: 20% glycerin aqueous solution Sample c: Purified water

After applying the three samples, the expert panel was asked to rate each sample's lack of stickiness and moisturizing sensation as good or bad. In the present invention, the condition for the panel is that they can answer sample a or sample b as good for moisturizing sensation, and sample b or sample c as good for lack of stickiness. Furthermore, for expert panels trained in the sensory evaluation of cosmetics, the condition for the expert panel is that they can answer only sample b as good for moisturizing sensation and lack of stickiness.

(Judgment criteria)
(Judgment): (Evaluation)
A: 5 or more people were good. B: 3 to 4 people were good. C: 1 to 2 people were good. D: All were bad.

As is clear from the results in Table 1, the Examples (Products 1 to 14 of the present invention) were superior to the Comparative Examples in terms of moisturizing feeling, sustained moisturizing feeling, and non-stickiness. On the other hand, Comparative Product 1, which does not contain component (A), and Comparative Product 2, which does not contain component (B), did not provide satisfactory quality in terms of moisturizing feeling and sustained moisturizing feeling, and Comparative Product 3, which does not contain component (C), and Comparative Product 4, in which component (C) was replaced with another plant extract, did not provide satisfactory quality in terms of non-stickiness.

Example 2 Oil-in-water emulsion cream Ingredients (%)
1. 1,3-butylene glycol 12
2. Glycerin 5
3. Purified water remaining 4. Niacinamide 4
5. Tranexamic acid 0.4
6. Licorice extract 0.1
7. Sodium N-stearoyl-N-methyl taurate 0.5
8. PEG-40 stearate 1
9. Heavy Liquid Isoparaffin 3
10. Dimethylpolysiloxane (25°C kinematic viscosity 10CS) 1
11. Ceramide 2 0.1
12. Ethyl oleate 0.01
13. DL-α-tocopherol acetate 0.01
14. Cetostearyl alcohol 2
15. Behenyl alcohol 1
16. Pentylene glycol 0.1
17. Acrylic acid/alkyl methacrylate copolymer 0.15
18. Gellan gum 0.1
19. Sodium hydroxide 2% solution 0.2
20. Fragrance (citrus) 0.1
(Production method)
A: Components 1 to 6 are uniformly dissolved and mixed at 70°C.
B: Components 7 to 16 are uniformly dissolved and mixed at 80°C.
C: Add B to A and emulsify at 70°C.
D: Components 17 to 20 were added to C and mixed, then cooled to 40°C to obtain an oil-in-water emulsion cream.
(evaluation)
The oil-in-water emulsion cream of Example 2 was excellent in all respects: moisturizing feeling, sustained moisturizing feeling, and non-stickiness.

Example 3 Water-in-oil liquid foundation Ingredients (%)
1. Spherical polyethylene (average particle size 5 μm) 5
2. Spherical silica (average particle size 5 μm) 1.5
3. Fine particle titanium dioxide *1 8
4. Fine particle zinc oxide *2 5
5. Isododecane 15
6. Hydrogenated polyisobutene 3
7. Ethylhexyl methoxycinnamate 5
8. Bisethylhexyloxyphenol methoxyphenyl triazine 1
9. Diisopropyl sebacate 3
10. Cetyl ethylhexanoate 2
11. Lauryl PEG-9
Polydimethylsiloxyethyl dimethicone※9 3
12. Purified water remaining 13. Niacinamide 7
14. Tranexamic acid 2
15. Ethanol 3
16. Tripropylene glycol 2
17. 1,3-butylene glycol 2
18. Methylenebisbenzotriazolyltetramethylbutylphenol 2
19. Honey 0.01
20. Eucalyptus extract 0.01
21. Carrot extract 0.01
22. Rosemary extract 0.01
23. Hydrolyzed collagen 0.001
24. Ceramide NG 0.005
25. Stearyl hectorite 0.3
26. Dimethylstearyl ammonium hectorite 0.2
27. Coloring agent *3 2
28.2% lecithin-treated talc 4
29. Glyceryl tribehenate 2
30. Propylene glycol dicaprylate 8
31. Glyceryl tri-2-ethylhexanoate 6
*1: 2% isopropyl triisostearate titanium treated *2: 3% methylhydrogenpolysiloxane treated *3: 2% triethoxycaprylylsilane treated pigment grade titanium dioxide 1.2%, 2% stearoyl glutamic acid disodium treated red iron oxide 0.2%, 1% lauroyl lysine yellow iron oxide 0.4%, black iron oxide 0.1%, konjo 0.05%, mica titanium 0.05% mixture (manufacturing method)
A: Components 29 to 31 are uniformly dissolved and mixed at 70°C.
B: Add ingredients 25 to 28 to A and mix uniformly using a roll mill.
C: Add B to A and mix evenly.
D: Add ingredients 1 to 11 to C and mix evenly.
E: Mix ingredients 12 to 24 uniformly at room temperature.
F: E was added to C and emulsified to obtain a water-in-oil liquid foundation.
(evaluation)
The water-in-oil liquid foundation of Example 3 was excellent in all respects: moisturizing feeling, sustained moisturizing feeling, and non-stickiness.

Example 4 Solid Powder Eye Shadow Ingredients (%)
1. Spherical cellulose (average particle size 12 μm) 2
2. Spherical hollow silica (average particle size 5 μm) 1.5
3. Synthetic gold mica 8
4. Zinc oxide (hexagonal plate shape, average particle size 0.3 μm) 3
5.2% Amodimethicone-treated mica Remaining amount 6. Amino-modified silicone-treated talc *4 20
7. Glass powder ※5 13
8. Aluminum powder ※6 8
9. Red iron oxide coated titanium mica ※7 12
10. (PET/methacrylate) laminate 5
11. Cetyl ethylhexanoate 3
12. Diisostearyl malate 8
13. Sorbitan sesquistearate 0.5
14. Hydrogenated polyisobutene 2
15. Microcrystalline wax 1
16. Tripropylene glycol 0.2
17. Polyoxybutylene polyoxyethylene polyoxypropylene glyceryl ether (3BO) (8EO) (5PO) 0.3
18. Purified water 3
19. Niacinamide 1
20. Tranexamic acid 5
21. Sodium pyrosulfite 0.01
22. Aloe extract 0.01
23. Sophora Extract 0.001
24. Ascorbic acid 0.1
25. Polyethylene glycol 0.1
26. Alkyl acrylate/methacrylic acid copolymer 0.2
27. Glycerin 3
28. Quaternium-18 Hectorite 0.4
29. Phenoxyethanol 0.2
30. Chlorphenesin 0.3
*4: SE-TA-EX (manufactured by Miyoshi Chemicals)
*5: Metashine MC2080PS (manufactured by Nippon Sheet Glass Co., Ltd.)
*6: COSMICOLOR CE. TECLA GR (manufactured by Toyo Aluminium Co., Ltd.)
*7: GEMTONE TAN OPAL G305 (manufactured by BASF)
(Production method)
A: Mix ingredients 16 to 30 evenly.
B: Heat ingredients 11 to 15 to 90°C and dissolve uniformly.
C: Mix ingredients 1 to 10 evenly.
D: Add B to C and mix uniformly at room temperature.
E: Add A to D at room temperature and mix to obtain a cosmetic composition.
F: 60 parts by mass of 30% ethanol water is added to 100 parts by mass of the cosmetic composition to prepare a slurry.
G: E was filled into a resin dish and compressed using a porous press head while removing the 30% ethanol water to obtain a solid powder eye shadow.
(evaluation)
The solid powder eye shadow of Example 4 was excellent in all respects: moisturizing feeling, sustained moisturizing feeling, and non-stickiness.

Example 5 Oil-based solid lip balm Ingredients (%)
1. Polyethylene 3
2. Microcrystalline wax 2
3. Fischer-Tropsch wax 5
4. Polybutene 6
5. Hydrogenated polyisobutene 3
6. Bisdiglyceryl polyacyladipate-2 4
7. Vaseline (melting point 58°C) 20
8. Dilinoleic acid di(phytosteryl/isostearyl)
/ Cetyl / Stearyl / Behenyl) 8
9. Dihydrogenated rosin dimer dilinoleyl 3
10. Diisostearyl malate 4
11. Polyglyceryl-2 diisostearate 6
12. Polyglyceryl-2 triisostearate balance 13. Polyglyceryl-10 decaisostearate 2
14. Polyglyceryl-10 Pentaisostearate 1
15. Tranexamic acid 0.1
16. Niacinamide 2
17. Tripropylene glycol 2
18. Dipropylene glycol 1
19. Yarrow extract 0.001
20. Senkyuu water 1
21. Red No. 218 0.01
22. Red No. 223 0.03
23. Yellow No. 5 0.05
24.
(Production method)
A: Heat ingredients 1 to 14 to 110°C and dissolve uniformly.
B: Add ingredients 15 to 24 to A and mix uniformly at room temperature.
C: B is heated to 90°C, filled into a stick container from the front, and cooled to -5°C.
D: C was returned to room temperature to obtain an oily solid lip cream.
(evaluation)
The oil-based solid lip cream of Example 5 was excellent in all respects: moisturizing feeling, sustained moisturizing feeling, and non-stickiness.

Example 6 Ointment Ingredients (%)
1. Tranexamic acid 8
2. Niacinamide 0.8
3. Orange juice 0.001
4. Polyethylene glycol (average molecular weight 400) 1
5. Purified water Remaining amount 6. 1,3-butylene glycol 3
7. Glycerin 4
8. Ethanol 8
9. Stearic acid 2
10. Stearyl alcohol 0.3
11. Behenyl alcohol 0.2
12. Vaseline 40
13. Lanolin 5
14. Fragrance (Citrus) 0.001
(Production method)
A: Dissolve ingredients 1 to 8 uniformly at room temperature.
B: Heat ingredients 9 to 14 to 60°C and mix uniformly.
C: Add A to B at 80°C and emulsify.
D: C was returned to room temperature and filled into a jar to obtain an ointment.
(evaluation)
The ointment of Example 6 was excellent in all respects: moisturizing feeling, sustained moisturizing feeling, and non-stickiness.

Claims (17)

The following components (A) to (D') :
(A) tranexamic acid or a salt thereof; (B) niacinamide; (C) at least one or more cosmetic ingredients selected from the group consisting of a plant of the genus Sophora of the Fabaceae family or an extract thereof, a plant of the genus Glycyrrhiza of the Fabaceae family or an extract thereof, a plant of the genus Achillea of the Asteraceae family or an extract thereof, a plant of the genus Daucus of the Apiaceae family or an extract thereof, a plant of the genus Camellia of the Theaceae family or an extract thereof, a plant of the genus Aloe of the Xanthomoniaceae family or an extract thereof, a plant of the genus Eucalyptus of the Myrtaceae family or an extract thereof, a plant of the genus Citrus of the Rutaceae family or an extract thereof, and a plant of the genus Rosemary of the Lamiaceae family or an extract thereof; (D') an external skin preparation or cosmetic preparation containing a polyhydric alcohol having 7 to 12 carbon atoms. The skin topical preparation or cosmetic according to claim 1, wherein the mass ratio of the components (A) and (B) is (A)/(B) = 0.05 to 15, and the mass ratio of the total amount of the components (A) and (B) to the component (C), [(A)+(B)]/(C), is 100 to 10,000. The following components (A) to (C):
A skin external preparation or cosmetic comprising (A) tranexamic acid or a salt thereof, (B) niacinamide, and (C) at least one beauty ingredient selected from the group consisting of a plant of the genus Sophora of the Fabaceae family or an extract thereof, a plant of the genus Glycyrrhiza of the Fabaceae family or an extract thereof, a plant of the genus Achillea of the Asteraceae family or an extract thereof, a plant of the genus Daucus of the Apiaceae family or an extract thereof, a plant of the genus Camellia of the Theaceae family or an extract thereof, a plant of the genus Aloe of the Xanthomoniaceae family or an extract thereof, a plant of the genus Eucalyptus of the Myrtaceae family or an extract thereof, a plant of the genus Citrus of the Rutaceae family or an extract thereof, and a plant of the genus Rosemary of the Lamiaceae family or an extract thereof,
A skin external preparation or cosmetic (excluding a lotion having the following formulation (1) and excluding a milky lotion having the following formulation (2)) in which the content mass ratio of the component (A) to the component (B) is (A)/(B)=0.05 to 15, and the content mass ratio of the total amount of the component (A) and the component (B) to the component (C), [(A)+(B)]/(C), is 100 to 10,000 .

The following components (A) to (C):
(A) Tranexamic acid or a salt thereof
(B) Niacinamide
(C) at least one cosmetic ingredient selected from the group consisting of a plant of the genus Sophora of the family Fabaceae or an extract thereof, a plant of the genus Glycyrrhiza of the family Fabaceae or an extract thereof, a plant of the genus Achillea of the family Asteraceae or an extract thereof, a plant of the genus Camellia of the family Theaceae or an extract thereof, a plant of the genus Aloe of the family Xanthomoniaceae or an extract thereof, a plant of the genus Eucalyptus of the family Myrtaceae or an extract thereof, and a plant of the genus Citrus of the family Rutaceae or an extract thereof
A skin external preparation or cosmetic comprising:
A skin external preparation or cosmetic, wherein the content mass ratio of the component (A) to the component (B) is (A)/(B)=0.05 to 15, and the content mass ratio of the total amount of the component (A) and the component (B) to the component (C), [(A)+(B)]/(C), is 100 to 10,000. The skin external preparation or cosmetic preparation according to claim 3 or 4 , further comprising component (D) a polyhydric alcohol having 5 to 12 carbon atoms. The skin external preparation or cosmetic preparation according to any one of claims 1, 2 and 5 , wherein the component (D') or the component (D) is at least one polyhydric alcohol selected from the group consisting of tripropylene glycol and 1,2-octanediol. The skin external preparation or cosmetic according to any one of claims 1 to 6 , wherein the content of the component (C) in the skin external preparation or cosmetic is 0.0001 to 0.01 mass%. The skin external preparation or cosmetic according to any one of claims 1 to 7 , wherein the mass ratio of the component (B) to the component (C) is (B)/(C) = 10 to 10,000. The skin topical preparation or cosmetic according to any one of claims 1 to 8, wherein the mass ratio of the component (A) to the component (C) is (A)/(C) = 10 to 10,000. The skin topical preparation or cosmetic preparation according to any one of claims 1 to 9, further comprising, as component (E), an aqueous component other than components (D) and (D'). The skin topical preparation or cosmetic preparation according to any one of claims 1 to 10, further comprising a component (F) a film-forming agent. 2. A skin topical preparation or cosmetic composition comprising component (A) tranexamic acid or a salt thereof, component (B) niacinamide, and component (D') a polyhydric alcohol having 7 to 12 carbon atoms, comprising component (C) an agent for reducing stickiness by at least one cosmetic ingredient selected from the group consisting of a plant of the genus Sophora of the family Fabaceae or an extract thereof, a plant of the genus Glycyrrhiza of the family Fabaceae or an extract thereof, a plant of the genus Achillea of the family Asteraceae or an extract thereof, a plant of the genus Daucus of the family Apiaceae or an extract thereof, a plant of the genus Camellia of the family Theaceae or an extract thereof, a plant of the genus Aloe of the family Xanthomoniaceae or an extract thereof, a plant of the genus Eucalyptus of the family Myrtaceae or an extract thereof, a plant of the genus Citrus of the family Rutaceae or an extract thereof, and a plant of the genus Rosemary of the family Lamiaceae or an extract thereof. A method for improving stickiness in a skin topical preparation or cosmetic composition containing component (A) tranexamic acid or a salt thereof, component (B) niacinamide, and component (D') a polyhydric alcohol having 7 to 12 carbon atoms, using component (C) at least one cosmetic ingredient selected from the group consisting of a plant of the genus Sophora of the Leguminosae family or an extract thereof, a plant of the genus Glycyrrhiza of the Leguminosae family or an extract thereof, a plant of the genus Achillea of the Asteraceae family or an extract thereof, a plant of the genus Daucus of the Umbelliferae family or an extract thereof, a plant of the genus Camellia of the Theaceae family or an extract thereof, a plant of the genus Aloe of the Xanthomoniaceae family or an extract thereof, a plant of the genus Eucalyptus of the Myrtaceae family or an extract thereof, a plant of the genus Citrus of the Rutaceae family or an extract thereof, and a plant of the genus Rosemary of the Lamiaceae family or an extract thereof. In a skin topical preparation or cosmetic composition containing component (A) tranexamic acid or a salt thereof, and component (B) niacinamide, component (C) is selected from the group consisting of a plant of the genus Sophora (Fabaceae) or an extract thereof, a plant of the genus Glycyrrhiza (Fabaceae) or an extract thereof, a plant of the genus Achillea (Asteraceae) or an extract thereof, a plant of the genus Daucus (Daucus carota) or an extract thereof, a plant of the genus Camellia (Theaceae) or an extract thereof, a plant of the genus Aloe (Xanthomoniaceae) or an extract thereof, a plant of the genus Eucalyptus (Myrtaceae) or an extract thereof, a plant of the genus Citrus (Rutaceae) or an extract thereof, and a plant of the genus Mann (Lamiaceae) or an extract thereof. A stickiness improving agent containing at least one or more cosmetic ingredients selected from the group consisting of plants of the genus Scutellaria or extracts thereof , wherein the mass ratio of the components (A) and (B) is (A)/(B)=0.05 to 15, and component (C) is used such that the mass ratio of the total amount of the components (A) and (B) to the component (C), [(A)+(B)]/(C), is 100 to 10,000 (however, excluding a lotion having the following formulation (1) and excluding a milky lotion having the following formulation (2)) .

In a skin topical preparation or cosmetic composition containing component (A) tranexamic acid or a salt thereof, and component (B) niacinamide, component (C) is a plant of the genus Sophora or an extract thereof of the genus Licorice of the genus Fabaceae or an extract thereof, a plant of the genus Achillea of the genus Asteraceae or an extract thereof, a plant of the genus Daucus of the genus Daucus of the genus Camellia of the genus Theaceae or an extract thereof, a plant of the genus Aloe of the genus Xanthomoniaceae or an extract thereof, a plant of the genus Eucalyptus of the genus Myrtaceae or an extract thereof, a plant of the genus Citrus of the genus Rutaceae or an extract thereof, and a plant of the genus Mannonia of the genus Lamiaceae or an extract thereof A method for improving stickiness using at least one cosmetic ingredient selected from the group consisting of Wax plants or extracts thereof , the method using component (C) such that the content mass ratio of component (A) to component (B) is (A)/(B)=0.05-15, and the content mass ratio of the total amount of component (A) and component (B) to component (C), [(A)+(B)]/(C), is 100-10,000 (however, excluding a lotion having the following formulation (1) and excluding a milky lotion having the following formulation (2)) .

A stickiness reducing agent for a skin topical preparation or cosmetic preparation containing component (A) tranexamic acid or a salt thereof, and component (B) niacinamide, comprising component (C) at least one or more cosmetic ingredients selected from the group consisting of a plant of the genus Sophora of the family Leguminosae or an extract thereof, a plant of the genus Glycyrrhiza of the family Leguminosae or an extract thereof, a plant of the genus Achillea of the family Asteraceae or an extract thereof, a plant of the genus Camellia of the family Theaceae or an extract thereof, a plant of the genus Aloe of the family Xanthomoniaceae or an extract thereof, a plant of the genus Eucalyptus of the family Myrtaceae or an extract thereof, and a plant of the genus Citrus of the family Rutaceae or an extract thereof, wherein the mass ratio of the components (A) and (B) is (A)/(B)=0.05 to 15, and component (C) is used so that the mass ratio of the total amount of the components (A) and (B) to the component (C), [(A)+(B)]/(C), is 100 to 10,000. A method for improving stickiness in a skin topical preparation or cosmetic preparation containing component (A) tranexamic acid or a salt thereof, and component (B) niacinamide, using component (C) at least one or more cosmetic ingredients selected from the group consisting of a plant of the genus Sophora of the family Fabaceae or an extract thereof, a plant of the genus Glycyrrhiza of the family Fabaceae or an extract thereof, a plant of the genus Achillea of the family Asteraceae or an extract thereof, a plant of the genus Camellia of the family Theaceae or an extract thereof, a plant of the genus Aloe of the family Xanthomoniaceae or an extract thereof, a plant of the genus Eucalyptus of the family Myrtaceae or an extract thereof, and a plant of the genus Citrus of the family Rutaceae or an extract thereof, wherein the mass ratio of the content of the component (A) to the content of the component (B) is (A)/(B)=0.05 to 15, and component (C) is used so that the mass ratio of the content of the total amount of the component (A) and the component (B) to the content of the component (C), [(A)+(B)]/(C), is 100 to 10,000.