JP7689822B2 - Oil-in-water emulsion cosmetics - Google Patents

Description

This disclosure relates to oil-in-water emulsion cosmetics.

In recent years, oil-in-water emulsion cosmetics that have emulsion stability and provide a variety of sensations when used have been developed.

Patent Document 1 discloses an emulsion composition that contains (a) 0.01 to 5% by weight of a polysiloxane-polyoxyalkylene copolymer, (b) 0.05 to 1% by weight of a nonionic surfactant, (c) 10 to 30% by weight of a moisturizing agent, and (d) 1 to 50% by weight of urea, and that exhibits excellent moisturizing effects while reducing the irritation caused by urea, and has a very refreshing feel when used.

Patent Document 2 discloses an emulsion composition that contains a poorly soluble drug, an oily component containing two or more types of higher alcohols, water, and a surfactant, in which one of the higher alcohols is behenyl alcohol, and that has excellent usability, drug dispersion stability, and emulsion stability.

Patent Document 3 discloses an emulsion composition containing 0.05 to 50.0 mass% of urea and/or glycoside of ascorbic acid, which is excellent in stability and has a refreshing feel without stickiness, and which is formulated with 0.01 to 5.0 mass% of (A) a polysiloxane-polyoxyalkylene copolymer and 0.05 to 1.0 mass% of (B) a nonionic surfactant or 0.05 to 5.0 mass% of a higher fatty acid having 12 or more carbon atoms.

In addition, Patent Documents 4 and 5 state in their background art that the stability of oil-in-water emulsion cosmetics decreases when whitening agents such as tranexamic acid are added.

JP 2001-247427 A JP 2001-354548 A JP 2002-249665 A JP 2019-142825 A JP 2018-123067 A

In some cases, whitening agents, anti-inflammatory agents, and the like are blended into the emulsion composition that constitutes the cosmetic. In particular, the use of acid-type or salt-type whitening agents or anti-inflammatory agents tends to destroy the emulsion balance between the aqueous phase and the oil phase, making it difficult to improve the emulsion stability of oil-in-water emulsion cosmetics that contain such agents. Furthermore, it has been even more difficult to adjust the feel of use of oil-in-water emulsion cosmetics that contain such agents.

Therefore, the subject of the present disclosure is to provide an oil-in-water emulsion cosmetic containing an acid or salt type whitening agent or anti-inflammatory agent, which has excellent emulsion stability and can provide a feeling of crumbling when used.

<Aspect 1>
An oil-in-water emulsion cosmetic comprising: a dispersion medium containing at least one agent selected from a whitening agent and an anti-inflammatory agent, and water; and oil droplets dispersed in the dispersion medium,
The oil droplets contain an oil component, a linear higher fatty acid having 16 or more carbon atoms, a monohydric higher alcohol, and a nonionic surfactant,
The whitening agent includes at least one selected from a salt-type whitening agent and an acid-type whitening agent,
The anti-inflammatory agent includes at least one selected from a salt-type anti-inflammatory agent and an acid-type anti-inflammatory agent,
The oil comprises a volatile acyclic silicone oil,
When a Brookfield viscometer is used in an atmosphere at 30° C., the viscosity ratio (V _{0.6 rpm} /V 12 rpm ) of the viscosity measured at 0.6 rpm (V _{0.6 rpm} ) to the viscosity measured at 12 rpm (V _{12 rpm} ) is 7.9 or more.
Oil-in-water emulsion cosmetic.
<Aspect 2>
A cosmetic preparation according to aspect 1, wherein a mass ratio of the linear higher fatty acid to the monohydric higher alcohol is 0.30 or more.
Aspect 3
A cosmetic preparation according to aspect 1 or 2, wherein the linear higher fatty acid, the higher alcohol, and the nonionic surfactant form an interfacial film with the oil droplets in an atmosphere at 25° C.
<Aspect 4>
Aspect 4. The cosmetic preparation according to any one of Aspects 1 to 3, wherein the linear higher fatty acid is at least one selected from stearic acid and behenic acid, and the higher alcohol is at least one selected from cetyl alcohol, isostearyl alcohol, stearyl alcohol, and behenyl alcohol.
<Aspect 5>
A cosmetic preparation according to any one of Aspects 1 to 4, wherein the volatile acyclic silicone oil is contained in the oil component in an amount of 15 mass % or more.
Aspect 6
A cosmetic preparation according to any one of Aspects 1 to 5, wherein the salt-type whitening agent is at least one selected from ascorbic acid, tranexamic acid, glycyrrhizic acid, nicotinic acid, kojic acid, ellagic acid, 1-piperidinepropionic acid, 3-O-ethyl-L-ascorbic acid, and alkoxysalicylic acid, and the acid-type whitening agent is at least one selected from ascorbic acid, tranexamic acid, glycyrrhizic acid, nicotinic acid, kojic acid, ellagic acid, 1-piperidinepropionic acid, 3-O-ethyl-L-ascorbic acid, and alkoxysalicylic acid.
Aspect 7
A cosmetic preparation according to any one of Aspects 1 to 6, wherein the anti-inflammatory agent is at least one selected from the group consisting of magnesium ascorbyl phosphate, dipotassium glycyrrhizinate, and ammonium glycyrrhizinate.
<Aspect 8>
A cosmetic preparation according to any one of Aspects 1 to 7, wherein at least one selected from the group consisting of the salt-type whitening agent, the acid-type whitening agent, the salt-type anti-inflammatory agent, and the acid-type anti-inflammatory agent is contained in an amount of 50 mass % or more based on the total amount of the whitening agent component and the anti-inflammatory agent component.
<Aspect 9>
A cosmetic preparation according to any one of Aspects 1 to 8, further comprising a dihydric higher alcohol.
Aspect 10
A cosmetic preparation according to any one of Aspects 1 to 9, wherein the content of the thickener is 1% by mass or less.

According to the present disclosure, it is possible to provide an oil-in-water emulsion cosmetic containing an acid or salt type whitening agent or an anti-inflammatory agent, which has excellent emulsion stability and can provide a feeling of crumbling when used.

The following describes in detail the embodiments of the present disclosure. The present disclosure is not limited to the following embodiments, and can be modified in various ways within the scope of the invention.

The oil-in-water emulsion cosmetic of the present disclosure (which may be simply referred to as "cosmetic") comprises a dispersion medium containing at least one selected from a whitening agent and an anti-inflammatory agent, and water, and oil droplets dispersed in this dispersion medium, the oil droplets containing an oil, a linear higher fatty acid having 16 or more carbon atoms, a monovalent higher alcohol, and a nonionic surfactant, the whitening agent containing at least one selected from a salt-type whitening agent and an acid-type whitening agent, the anti-inflammatory agent containing at least one selected from a salt-type anti-inflammatory agent and an acid-type anti-inflammatory agent, the oil containing a volatile acyclic silicone oil, and in addition, when a Brookfield viscometer is used in an atmosphere of 30°C, the viscosity ratio ( _{V0.6rpm/V12rpm} ) between the viscosity measured at 0.6 rpm ( _V0.6rpm ) and the viscosity measured at _{12 rpm} ( _V12rpm ) is 7.9 or more.

Although not limited by the theory, it is believed that the principle of action by which such oil-in-water emulsion cosmetics have excellent emulsion stability and can achieve a feeling of crumbling, i.e., a specific viscosity ratio, is as follows.

When an acid or salt type whitening agent or anti-inflammatory agent is blended into an oil-in-water emulsion cosmetic, the emulsion balance is lost, and the emulsion stability of the cosmetic is expected to decrease. Therefore, even if various documents disclose an oil-in-water emulsion composition containing a linear higher fatty acid having 16 or more carbon atoms, a monohydric higher alcohol, and a nonionic surfactant, a person skilled in the art would not normally think of blending an acid or salt type whitening agent or anti-inflammatory agent that could destabilize the emulsion into such a composition.

However, the present inventors have unexpectedly discovered that emulsified particles (oil droplets) prepared using specific materials, namely, a volatile acyclic silicone oil, a linear higher fatty acid having 16 or more carbon atoms, a monohydric higher alcohol, and a nonionic surfactant, have excellent emulsion stability even when an acid or salt type whitening agent or an anti-inflammatory agent is blended.

The manifestation of such emulsion stability is believed to be influenced by the fact that, for example, linear higher fatty acids having 16 or more carbon atoms, monovalent higher alcohols, and nonionic surfactants form an interfacial membrane around the emulsion particles at room temperature, for example, in an atmosphere of 25°C or 30°C, which is a gel membrane or liquid crystal membrane based on lamellar liquid crystals, which is relatively strong compared to micellar structures, etc.

Here, the oil-in-water emulsion cosmetic of the present disclosure can be prepared, for example, by mixing the above-mentioned interfacial membrane components and oil while heating to about 70 to 90°C to prepare an oil phase solution, then mixing water and a whitening agent and/or an anti-inflammatory agent while heating to about 70 to 90°C to prepare an aqueous phase solution, gradually adding the oil phase solution to this aqueous phase solution while stirring, and then cooling to room temperature. It is believed that during this cooling stage, the interfacial membrane components dissolved in the oil phase separate from the oil and solidify near the interface between the oil phase and the aqueous phase, forming an interfacial membrane.

The oil-in-water emulsion cosmetic of the present disclosure uses a volatile acyclic silicone oil as the oil. This silicone oil is less compatible with the above-mentioned interfacial film constituent components than, for example, cyclic silicone oils such as cyclopentasiloxane. Therefore, when a volatile acyclic silicone oil is used as the oil, the interfacial film constituent components are more easily separated from the oil than in the case of cyclic silicone oils, which are more compatible. As a result, it is believed that a larger amount of the interfacial film constituent components migrate to the vicinity of the interface between the oil phase and the water phase, forming a stronger interfacial film.

In this way, the oil-in-water emulsion cosmetic of the present disclosure is believed to have excellent emulsion stability even when an acid- or salt-type whitening agent or anti-inflammatory agent that can destabilize the emulsion is blended, because the interfacial film is firmly formed. Furthermore, the presence of such a strong interfacial film is believed to affect the sense of collapse of the cosmetic of the present disclosure. That is, unlike particles with a micelle structure, emulsion particles having an interfacial film are believed to exhibit a sense of collapse because the interfacial film breaks all at once when a load exceeding a limit value is applied.

The definitions of terms used in this disclosure are as follows:

In the present disclosure, the term "feeling of crumbling" refers to a feeling of use in which the viscosity of the cosmetic drops suddenly when a load is applied to the cosmetic. Specifically, in the present disclosure, the term "feeling of crumbling" refers to a feeling of use in which the cosmetic has high viscosity and low fluidity when placed on the skin, etc., but when the cosmetic is rubbed on the skin, etc., the viscosity drops and the cosmetic becomes smooth and highly fluid. This feeling of crumbling can be defined as the viscosity ratio (V 0.6 rpm /V 12 rpm ) between the viscosity measured at 0.6 rpm (V _{0.6 rpm} ) and the viscosity measured at 12 rpm (V _{12 rpm} ) when a B-type viscometer (TVB-type viscometer _TVB -10, manufactured by Toki Sangyo Co., Ltd., rotor number _L3 ) is used in an atmosphere of 30° C., and the state in which this viscosity ratio is 7.9 or more is intended.

<Oil-in-water emulsion cosmetics>
The oil-in-water emulsion cosmetic of the present disclosure has excellent emulsion stability. Here, emulsion stability refers to a state in which the emulsion does not separate, and preferably a state in which there is little or no change in size of emulsion particles (oil droplets), for example, at 0° C. to 37° C. for 4 weeks, and preferably at 50° C. for 4 weeks.

In addition, the oil-in-water emulsion cosmetic of the present disclosure can exhibit a feeling of crumbling. As described above, the feeling of crumbling can be determined by the viscosity ratio ( _V0.6rpm / _V12rpm ). The viscosity ratio can be 7.9 or more, 8.0 or more, 8.1 or more, 8.3 or more, 8.5 or more, 8.7 or more, 9.0 or more, 9.5 or more, or 10.0 or more. There is no particular limit to the upper limit of the viscosity ratio, but it can be, for example, 30.0 or less, 25.0 or less, 20.0 or less, or 15.0 or less.

The viscosity ratio of the oil-in-water emulsion cosmetic can be controlled, for example, by adjusting at least one of the following conditions (a) to (c):
(a) The mass ratio of the linear higher fatty acid to the monohydric higher alcohol.
(b) Types of oils (e.g., volatile acyclic silicone oils and polar oils), linear higher fatty acids having 16 or more carbon atoms, monohydric higher alcohols, and nonionic surfactants, and combinations thereof.
(c) The proportion of volatile acyclic silicone oil and/or polar oil in the oil content.

There are no particular limitations on the viscosity (V _{12 rpm} ) of the oil-in-water emulsion cosmetic composition of the present disclosure, measured at 12 rpm, and it can be determined as appropriate taking into consideration the application performance, usability, and the like of the cosmetic composition. For example, the viscosity (V _{12 rpm} ) when measured in an atmosphere of 30° C. using a B-type viscometer (TVB type viscometer TVB-10, manufactured by Toki Sangyo Co., Ltd., rotor number L3) can be 20,000 mPa·s or less, 18,000 mPa·s or less, 15,000 mPa·s or less, 12,000 mPa·s or less, 10,000 mPa·s or less, 8,000 mPa·s or less, 6,000 mPa·s or less, or 5,000 mPa·s or less, and can be 2,000 mPa·s or more, 2,200 mPa·s or more, 2,500 mPa·s or more, 2,700 mPa·s or more, or 3,000 mPa·s or more.

<Dispersion medium>
The oil-in-water emulsion cosmetic of the present disclosure contains a dispersion medium, and this dispersion medium contains at least one whitening agent selected from a salt-type whitening agent and an acid-type whitening agent, and/or at least one anti-inflammatory agent selected from a salt-type anti-inflammatory agent and an acid-type anti-inflammatory agent, and water.

(skin whitening agent)
The blending amounts of the salt-type whitening agent and the acid-type whitening agent are not particularly limited, and can be, for example, each independently, 0.01% by mass or more, 0.05% by mass or more, 0.1% by mass or more, 0.3% by mass or more, 0.5% by mass or more, 0.7% by mass or more, or 1.0% by mass or more relative to the total amount of the cosmetic, and can be 15.0% by mass or less, 10.0% by mass or less, 8.0% by mass or less, or 5.0% by mass or less.

Examples of salt-type whitening agents include ascorbate, tranexamate, glycyrrhizinate, nicotinate, kojate, ellagate, 1-piperidinepropionate, 3-O-ethyl-L-ascorbate, and alkoxysalicylate (e.g., 4-methoxysalicylate). Examples of salts of salt-type whitening agents include alkali metal salts such as sodium salt and potassium salt; alkaline earth metal salts such as calcium salt and magnesium salt; zinc salt; iron salt; ammonium salt; salts with basic amino acids such as arginine, lysine, histidine, and ornithine; and salts with amines such as monoethanolamine, diethanolamine, and triethanolamine. Salt-type whitening agents can be used alone or in combination of two or more.

There are no particular limitations on the acid-type whitening agents, and examples include ascorbic acid (L-ascorbic acid), tranexamic acid, glycyrrhizic acid, nicotinic acid, kojic acid, ellagic acid, 1-piperidinepropionic acid, 3-O-ethyl-L-ascorbic acid, and alkoxysalicylic acids (e.g., 4-methoxysalicylic acid). Acid-type whitening agents can be used alone or in combination of two or more.

(Anti-inflammatory agent)
The blending amounts of the salt-type anti-inflammatory agent and the acid-type anti-inflammatory agent are not particularly limited, and can be, for example, each independently, 0.01% by mass or more, 0.05% by mass or more, 0.1% by mass or more, 0.3% by mass or more, 0.5% by mass or more, 0.7% by mass or more, or 1.0% by mass or more relative to the total amount of the cosmetic, and can be 15.0% by mass or less, 10.0% by mass or less, 8.0% by mass or less, or 5.0% by mass or less.

Examples of salt-type anti-inflammatory agents include magnesium L-ascorbyl phosphate, dipotassium glycyrrhizinate, and ammonium glycyrrhizinate. Salt-type anti-inflammatory agents can be used alone or in combination of two or more.

In this disclosure, among the above-mentioned whitening agents and anti-inflammatory agents, those that exhibit both whitening and anti-inflammatory properties are treated as whitening agents.

(water)
The amount of water to be blended is not particularly limited, and from the viewpoints of emulsion stability, feeling of crumbling, etc., it can be, for example, 50% by mass or more, 60% by mass or more, 70% by mass or more, or 80% by mass or more relative to the total amount of the cosmetic, and can be 95% by mass or less, 90% by mass or less, or 85% by mass or less.

There are no particular limitations on the water that can be used in the oil-in-water emulsion cosmetic of the present disclosure, and for example, water used in cosmetics, quasi-drugs, etc. can be used. Examples of such water include ion-exchanged water, distilled water, ultrapure water, and tap water.

<Oil drop>
The oil droplets as the oil phase or dispersed phase in the oil-in-water emulsion cosmetic contain an oil, a linear higher fatty acid having 16 or more carbon atoms, a monovalent higher alcohol, and a nonionic surfactant. Of these components, the linear higher fatty acid having 16 or more carbon atoms, the monovalent higher alcohol, and the nonionic surfactant can form an interfacial film of the oil droplets. Such an interfacial film can be confirmed, for example, using an optical microscope.

The inventors have found that, for example, when an oil-in-water emulsion composition is prepared by a liquid crystal emulsification method in which a linear higher fatty acid having 16 or more carbon atoms, a monohydric higher alcohol, and a nonionic surfactant are mixed with an oil while heating to prepare a solution, and the solution is then added to heated water, oil droplets (emulsion particles) having such an interfacial membrane can be obtained.

There is no particular limit to the average particle size of the oil droplets that are the dispersed phase. The average particle size of such oil droplets immediately after production can be, for example, 10 μm or less, 7 μm or less, 5 μm or less, or 3 μm or less. The lower limit of the average particle size is not particularly limited, but can be, for example, 500 nm or more, 700 nm or more, or 1 μm or more. Here, the average particle size of the oil droplets can be defined as the average value of the diameter of a circle equivalent to the projected area of 10 or more, preferably 100 or more, oil droplets observed with an optical microscope.

(Oil content)
The content of oil in the oil-in-water emulsion cosmetic of the present disclosure is not particularly limited, and can be, for example, 0.5% by mass or more, 1% by mass or more, 3% by mass or more, 5% by mass or more, 7% by mass or more, 10% by mass or more, 13% by mass or more, or 15% by mass or more relative to the total amount of the cosmetic, and can be 50% by mass or less, 40% by mass or less, 30% by mass or less, 25% by mass or less, or 20% by mass or less.

The oil-in-water emulsion cosmetic of the present disclosure contains at least a volatile acyclic silicone oil as an oil component. The volatile acyclic silicone oil can improve the film strength of the interfacial film of the oil droplets. In addition, the use of a volatile acyclic silicone oil that can improve the film strength of the interfacial film can also increase the static viscosity while suppressing an increase in the dynamic viscosity of the cosmetic, making it easier to increase the viscosity ratio, i.e., to create a feeling of crumbling.

As the volatile acyclic silicone oil, for example, a volatile linear silicone oil or a volatile branched silicone oil can be used. Among them, a volatile linear silicone oil is preferred. The volatile acyclic silicone oil can be used alone or in combination of two or more kinds.

Here, "volatile" refers to a material that exhibits a volatile content of more than 5% when left at 105°C under atmospheric pressure for 3 hours. From the viewpoint of obtaining excellent film strength and a feeling of crumbling, the volatile content as an indicator of volatility is preferably 10% or more, 20% or more, 40% or more, 50% or more, 60% or more, 80% or more, or 100%. Alternatively, the boiling point at 1 atmosphere (101.325 kPa) can be used as an indicator of volatility. From the viewpoint of obtaining excellent film strength and a feeling of crumbling, this boiling point is preferably 250°C or less, 240°C or less, or 230°C or less, and is preferably 80°C or more, 100°C or more, 120°C or more, 150°C or more, or 160°C or more. In addition, in this disclosure, "non-volatile" refers to a material that exhibits a volatile content of 5% or less when left at 105°C for 3 hours.

Examples of volatile linear silicone oils include low molecular weight linear dimethylpolysiloxanes such as dimethylpolysiloxane with a viscosity of 0.65 cSt (sometimes called "dimethicone"), dimethylpolysiloxane with a viscosity of 1 cSt, dimethylpolysiloxane with a viscosity of 1.5 cSt, and dimethylpolysiloxane with a viscosity of 2 cSt. Here, these viscosities refer to the kinetic viscosity in an atmosphere at 25°C.

Examples of volatile branched silicone oils include low molecular weight branched siloxanes such as methyltrimethicone, tris(trimethylsilyl)methylsilane, and tetrakis(trimethylsilyl)silane.

The content of volatile acyclic silicone oil in the oil-in-water emulsion cosmetic of the present disclosure is not particularly limited, and may be, for example, 0.1% by mass or more, 0.3% by mass or more, 0.5% by mass or more, 0.7% by mass or more, or 1.0% by mass or more relative to the total amount of the cosmetic, and may also be less than 20.0% by mass, 15.0% by mass or less, 10.0% by mass or less, 9.0% by mass or less, 8.0% by mass or less, 7.0% by mass or less, 6.0% by mass or less, 5.0% by mass or less, 4.0% by mass or less, or 3.0% by mass or less. Alternatively, the content of the volatile non-cyclic silicone oil can be 15% by mass or more, 17% by mass or more, or 20% by mass or more, based on the total amount of oil, and can be about 100% by mass or less, less than about 100% by mass, about 90% by mass or less, about 80% by mass or less, about 70% by mass or less, about 60% by mass or less, about 50% by mass or less, about 40% by mass or less, or about 30% by mass or less.

In some embodiments, the oil-in-water emulsion cosmetic of the present disclosure may contain a volatile cyclic silicone oil and a nonvolatile acyclic silicone oil as the oil. However, when the volatile acyclic silicone oil is added to further improve the film strength of the interface film, the content of the volatile cyclic silicone oil and the nonvolatile acyclic silicone oil is preferably less than 20.0 mass%, 15.0 mass% or less, 10.0 mass% or less, 7.0 mass% or less, 5.0 mass% or less, 3.0 mass% or less, or 1.0 mass% or less, based on the total amount of the cosmetic. Alternatively, the content of the volatile cyclic silicone oil and the nonvolatile acyclic silicone oil is preferably less than 10.0 mass%, 7.0 mass% or less, 5.0 mass% or less, 3.0 mass% or less, or 1.0 mass% or less, based on the total amount of the oil. Furthermore, it is more preferable that the volatile cyclic silicone oil and/or the nonvolatile acyclic silicone oil is not added to the oil, and it is particularly preferable that the volatile cyclic silicone oil is not added to the oil.

In some embodiments, the oil-in-water emulsion cosmetic of the present disclosure may contain a polar oil as the oil component. Among oil components, polar oils have the properties of oil, but also have polarity, and therefore have a higher affinity with water than non-polar oils. Therefore, the emulsion balance between the water phase and the oil phase is easily broken, and it is generally difficult to improve the emulsion stability of an oil-in-water emulsion cosmetic containing a polar oil. However, as described above, the oil-in-water emulsion cosmetic of the present disclosure has a strong interfacial membrane formed around the oil droplets (emulsion particles), which encases the polar oil that is likely to break the emulsion balance, and therefore can exhibit good emulsion stability and a sense of collapse even when such a polar oil is used.

The polar oil may contain, for example, at least one selected from polar oils having an IOB of 0.10 or more and ultraviolet absorbers having an IOB of 0.10 or more. These oils may be contained in an amount of 50 mass% or more, 60 mass% or more, 65 mass% or more, or 70 mass% or more relative to the total amount of oil. There is no particular limit to the upper limit of these oils, and they may be, for example, 85 mass% or less, 80 mass% or less, or 75 mass% or less. Here, organic ultraviolet absorbers having an IOB of 0.10 or more may be considered to be polar oils.

The IOB value of the polar oil and the UV absorber can be, for example, 0.10 or more, 0.11 or more, 0.12 or more, or 0.13 or more, and can be 0.50 or less, 0.45 or less, or 0.40 or less. Here, the IOB value is an abbreviation for Inorganic/Organic Balance, which is a value that represents the ratio of the inorganic value to the organic value, and is an index that indicates the degree of polarity of an organic compound. Specifically, the IOB value is expressed as IOB value = inorganic value / organic value. For each "inorganic value" and "organic value", for example, an "organic value" of 20 for one carbon atom in a molecule and an "inorganic value" of 100 for one hydroxyl group are set according to the type of atom or functional group, and the IOB value of an organic compound can be calculated by accumulating the "inorganic value" and "organic value" of all atoms and functional groups in the organic compound (see, for example, Koda Yoshio, "Organic Conceptual Diagram - Basics and Applications", pp. 11-17, Sankyo Publishing, 1984).

Examples of polar oils with an IOB of 0.10 or more include isopropyl myristate (IOB value = 0.18), octyl palmitate (IOB value = 0.13), isopropyl palmitate (IOB value = 0.16), butyl stearate (IOB value = 0.14), hexyl laurate (IOB value = 0.17), myristyl myristate (IOB value = 0.11), decyl oleate (IOB value = 0.11), isononyl isononanoate (IOB value = 0.20), and isononane. Isotridecyl acetate (IOB value = 0.15), cetyl ethylhexanoate (IOB value = 0.13), pentaerythrityl tetraethylhexanoate (IOB value = 0.35), diethylhexyl succinate (IOB value = 0.32), dioctyl succinate (IOB value = 0.36), glycol distearate (IOB value = 0.16), glyceryl diisostearate (IOB value = 0.29), neopentyl glycol dicaprate (IOB value = 0.25), diisomalate (IOB value = 0.16), Sostearyl (IOB value = 0.28), trimethylolpropane triisostearate (IOB value = 0.16), glyceryl tri-2-ethylhexanoate (triethylhexanoin) (IOB value = 0.35), trimethylolpropane trioctanoate (IOB value = 0.33), trimethylolpropane triisostearate (IOB value = 0.16), diisobutyl adipate (IOB value = 0.46), N-lauroyl-L-glutamic acid-2-octyldodecyl Examples include diisopropyl ether (IOB value = 0.29), 2-hexyldecyl adipate (IOB value = 0.16), diisopropyl sebacate (IOB value = 0.40), 2-ethylhexyl palmitate (IOB value = 0.13), 2-ethylhexyl ethylhexanoate (IOB value = 0.2), triisostearin (IOB value = 0.16), PPG-3 dipivalate (IOB value = 0.52), and tri(caprylic acid/capric acid)glyceryl (IOB value = 0.33). These polar oils can be used alone or in combination of two or more.

Examples of ultraviolet absorbers with an IOB of 0.10 or more include organic ultraviolet absorbers such as ethylhexyl methoxycinnamate, octocrylene, polysilicone-15, t-butyl methoxydibenzoylmethane, ethylhexyl triazone, bisethylhexyloxyphenol methoxyphenyl triazine, diethylaminohydroxybenzoyl hexyl benzoate, oxybenzone-3, methylene bisbenzotriazolyl tetramethylbutylphenol, homosalate, and ethylhexyl salicylate. These ultraviolet absorbers can be used alone or in combination of two or more.

(Straight-chain higher fatty acids with 16 or more carbon atoms)
The content of linear higher fatty acids having 16 or more carbon atoms in the oil-in-water emulsion cosmetic of the present disclosure is not particularly limited, and can be, for example, 0.10 mass% or more, 0.15 mass% or more, 0.20 mass% or more, 0.25 mass% or more, or 0.30 mass% or more relative to the total amount of the cosmetic, and can be 5.0 mass% or less, 3.0 mass% or less, or 1.0 mass% or less.

The oil-in-water emulsion cosmetic of the present disclosure may contain higher fatty acids other than linear higher fatty acids having 16 or more carbon atoms, for example, linear or branched higher fatty acids having less than 16 carbon atoms, or branched higher fatty acids having 16 or more carbon atoms, as long as the effects of the present invention are not adversely affected. From the viewpoint of crumbling sensation and emulsion stability, however, it is preferable that these other higher fatty acids are contained in an amount of, for example, less than 0.10% by mass, 0.05% by mass or less, or 0.01% by mass or less relative to the total amount of the cosmetic, and it is even more preferable that these other higher fatty acids are not contained in the cosmetic.

The number of carbon atoms in the linear higher fatty acid can be 16 or more, or 18 or more, and can be 25 or less, 24 or less, or 22 or less.

Examples of such linear higher fatty acids include saturated fatty acids such as palmitic acid, stearic acid, arachidic acid, behenic acid (behenic acid), and lignoceric acid; and unsaturated fatty acids such as palmitoleic acid, oleic acid, linoleic acid, α-linolenic acid, γ-linolenic acid, arachidonic acid, eicosapentaenoic acid, and docosahexanoic acid. Among these, from the viewpoint of the feeling of crumbling, saturated fatty acids are preferred, stearic acid and behenic acid are more preferred, and behenic acid is particularly preferred. These linear higher fatty acids can be used alone or in combination of two or more kinds.

(Monohydric higher alcohol)
The content of the monohydric higher alcohol in the oil-in-water emulsion cosmetic of the present disclosure is not particularly limited, and can be, for example, 0.1 mass% or more, 0.3 mass% or more, 0.5 mass% or more, 0.7 mass% or more, or 1.0 mass% or more relative to the total amount of the cosmetic, and can be 5.0 mass% or less, 4.0 mass% or less, or 3.0 mass% or less.

There are no particular limitations on the monohydric higher alcohol, and for example, a saturated or unsaturated monohydric aliphatic alcohol can be used, and either linear or branched, but linear is preferred. From the standpoint of emulsion stability and crumbling sensation, a monohydric higher alcohol that is solid at room temperature, for example, is preferred, which is likely to form an interfacial film such as a gel film or liquid crystal film based on lamellar liquid crystals at room temperature or higher together with a linear higher fatty acid and a nonionic surfactant. Here, in this disclosure, "room temperature" refers to a range of 5°C to 35°C.

Examples of such monohydric higher alcohols include higher alcohols with a melting point of 40°C or higher, for example, monohydric aliphatic alcohols having 10 to 30 carbon atoms. Specific examples include stearyl alcohol, isostearyl alcohol, oleyl alcohol, octyldodecanol, cholesterol, sitosterol, cetyl alcohol (cetanol), cetostearyl alcohol, decyltetradecanol, phytosterol, hexyldecanol, behenyl alcohol, lauryl alcohol, lanolin alcohol, hydrogenated lanolin alcohol, etc. Among these, cetyl alcohol, isostearyl alcohol, stearyl alcohol, and behenyl alcohol are preferred, and behenyl alcohol is more preferred, from the viewpoints of emulsion stability and crumbling sensation. These higher alcohols can be used alone or in combination of two or more kinds.

From the viewpoints of emulsion stability, crumbling sensation, etc., the mass ratio of linear higher fatty acid having 16 or more carbon atoms to monovalent higher alcohol is preferably 0.30 or more, 0.35 or more, 0.40 or more, 0.45 or more, 0.50 or more, 0.55 or more, 0.60 or more, or 0.65 or more, and is preferably 2.0 or less, 1.7 or less, 1.5 or less, or 1.3 or less.

(Nonionic Surfactant)
The content of the nonionic surfactant in the oil-in-water emulsion cosmetic of the present disclosure is not particularly limited, and can be, for example, 0.1 mass % or more, 0.3 mass % or more, or 0.5 mass % or more, and can be 5.0 mass % or less, 4.0 mass % or less, 3.0 mass % or less, or 2.0 mass % or less, relative to the total amount of the cosmetic.

There are no particular limitations on the nonionic surfactant, and examples thereof include polyoxyalkylene alkyl ethers, polyalkylene glycol fatty acid esters, POE alkyl ethers, POE-POP alkyl ethers, PEG fatty acid esters, polyglycerin fatty acid esters, POE glycerin fatty acid esters, PEG glyceryl isostearate, and silicone surfactants. These can be used alone or in combination of two or more.

Examples of polyoxyalkylene alkyl ethers include polyoxyethylene behenyl ether and polyoxyethylene stearyl ether.

Examples of polyalkylene glycol fatty acid esters include polyethylene glycol monostearate, polyethylene glycol monooleate, etc.

Examples of POE alkyl ethers include POE (2) lauryl ether, POE (4.2) lauryl ether, POE (9) lauryl ether, POE (5.5) cetyl ether, POE (7) cetyl ether, POE (10) cetyl ether, POE (15) cetyl ether, POE (20) cetyl ether, POE (23) cetyl ether, POE (4) stearyl ether, POE (20) stearyl ether, POE (7) oleyl ether, POE (10) oleyl ether, and POE (15) oleyl ether. ether, POE(20) oleyl ether, POE(50) oleyl ether, POE(10) behenyl ether, POE(20) behenyl ether, POE(30) behenyl ether, POE(2)(C12-15) alkyl ether, POE(4)(C12-15) alkyl ether, POE(10)(C12-15) alkyl ether, POE(5) secondary alkyl ether, POE(7) secondary alkyl ether, POE(9) alkyl ether, POE(12) alkyl ether, etc.

Examples of POE/POP alkyl ethers include POE(1) polyoxypropylene (POP)(4) cetyl ether, POE(10)POP(4) cetyl ether, POE(20)POP(8) cetyl ether, POE(20)POP(6) decyltetradecyl ether, and POE(30)POP(6) decyltetradecyl ether.

Examples of PEG fatty acid esters include polyethylene glycol monolaurate (hereinafter abbreviated as PEG) (10), PEG monostearate (10), PEG monostearate (25), PEG monostearate (40), PEG monostearate (45), PEG monostearate (55), PEG monostearate (100), PEG monooleate (10), PEG distearate, PEG diisostearate, PEG (40) hydrogenated castor oil, PEG (50) hydrogenated castor oil, PEG (60) hydrogenated castor oil, and PEG (100) hydrogenated castor oil.

Examples of polyglycerol fatty acid esters include hexaglyceryl monolaurate, hexaglyceryl monomyristate, hexaglyceryl monostearate, hexaglyceryl monooleate, decaglyceryl monolaurate, decaglyceryl monomyristate, decaglyceryl monostearate, decaglyceryl monoisostearate, decaglyceryl monooleate, decaglyceryl distearate, and decaglyceryl diisostearate.

Examples of POE glycerin fatty acid esters include polyoxyethylene (POE) (5) glyceryl monostearate, POE (15) glyceryl monostearate, POE (5) glyceryl monooleate, and POE (15) glyceryl monooleate.

Examples of PEG glyceryl isostearate include PEG (8) glyceryl isostearate, PEG (10) glyceryl isostearate, PEG (15) glyceryl isostearate, PEG (20) glyceryl isostearate, PEG (25) glyceryl isostearate, PEG glyceryl (30) isostearate, PEG (40) glyceryl isostearate, PEG (50) glyceryl isostearate, and PEG (60) glyceryl isostearate.

Examples of silicone surfactants include PEG (7) dimethicone and PEG (10) dimethicone.

Among these, from the viewpoints of emulsion stability, feeling of crumbling, etc., PEG fatty acid esters, PEG glyceryl isostearate, and silicone surfactants are preferred, and PEG (60) hydrogenated castor oil, PEG (60) glyceryl isostearate, and PEG (10) dimethicone are more preferred, and although these may be used alone, it is preferable to use them in combination.

<Optional ingredients>
The oil-in-water emulsion cosmetic of the present disclosure may contain various components as appropriate, provided that the effects of the present invention are not adversely affected. Examples of the various components include additive components that can be typically added to cosmetics. For example, moisturizing agents such as 1,3-butylene glycol, propylene glycol, and dynamite glycerin, anionic surfactants, cationic surfactants, amphoteric surfactants, water-soluble polymers, oil-soluble polymers, film-forming agents such as siliconized polysaccharides, sequestering agents, lower alcohols such as ethanol, polyhydric alcohols such as PEG 6000 and dipropylene glycol, higher alcohols other than those mentioned above, various extracts, sugars, amino acids, organic amines, polymer emulsions, chelating agents, UV absorbers other than those mentioned above, UV scattering agents such as zinc oxide, pH adjusters, skin nutrients, vitamins, water-soluble drugs applicable to medicines, quasi-drugs, cosmetics, etc., whitening agents other than those mentioned above, anti-inflammatory agents other than those mentioned above, antioxidants, buffers, preservatives, antioxidant assistants, thickeners, dispersants, propellants, organic powders, clay minerals, pigments, dyes, colorants, fragrances, acid components, alkaline components, polar or non-polar oils other than those mentioned above, and the like. These optional components may be used alone or in combination of two or more, and may be appropriately blended in the oil phase and/or the aqueous phase.

Among these additives, it is preferable to use higher alcohols other than those mentioned above from the viewpoints of suppressing crystallization of the interface film, crumbling feeling, etc. As such higher alcohols, dihydric higher alcohols are preferable, and batyl alcohol is particularly preferable.

In addition, since it is generally difficult to improve the emulsion stability of oil-in-water emulsion cosmetics that use salt-type or acid-type whitening agents or anti-inflammatory agents and polar oils, thickeners, particularly water-soluble thickeners, are usually used to ensure the emulsion stability of such cosmetics. However, although the incorporation of a thickener may improve emulsion stability, it may cause a feeling of collapse, i.e., may have a negative effect on achieving a specific viscosity ratio, and may also tend to cause a sticky feeling.

On the other hand, the emulsion particles (oil droplets) in the oil-in-water emulsion cosmetic of the present disclosure are prepared using specific materials, namely, a volatile acyclic silicone oil, a linear higher fatty acid having 16 or more carbon atoms, a monovalent higher alcohol, and a nonionic surfactant, and have excellent emulsion stability, so the cosmetic of the present disclosure does not need to substantially contain a thickener. That is, the thickener may be blended in an amount of 1% by mass or less, 0.5% by mass or less, 0.1% by mass or less, 0.01% by mass or less, or 0.001% by mass or less relative to the total amount of the cosmetic, but it is advantageous not to use a thickener from the standpoint of the feeling of crumbling, etc.

The oil-in-water emulsion cosmetic of the present disclosure may contain whitening agents and/or anti-inflammatory agents other than those described above. In such cases, at least one selected from the group consisting of salt-type whitening agents, acid-type whitening agents, salt-type anti-inflammatory agents, and acid-type anti-inflammatory agents may be contained in an amount of 50% by mass or more, 60% by mass or more, 70% by mass or more, 80% by mass or more, or 90% by mass or more based on the total amount of the whitening agent components and the anti-inflammatory agent components. Examples of whitening agents other than those mentioned above include ascorbic acid derivatives (e.g., ascorbic acid glucoside), tranexamic acid derivatives, glycyrrhizic acid derivatives, nicotinic acid derivatives, kojic acid derivatives (e.g., kojic acid dipalmitate), ellagic acid derivatives, alkoxysalicylic acid derivatives, hydroquinone, α-arbutin, β-arbutin, nicotinic acid amide, astaxanthin, histidine dithiooctanamide (Na/Zn), chamomile extract, licorice extract, placenta extract, rosemary extract, rucinol, and magnolignan. Examples of anti-inflammatory agents other than those mentioned above include glycyrrhizin and allantoin.

<<Uses of oil-in-water emulsion cosmetics>>
The oil-in-water emulsion cosmetic of the present disclosure can provide a feeling of crumbling, such as a sudden drop in the viscosity of the cosmetic when a load is applied. Therefore, the cosmetic of the present disclosure that provides such a feeling of use can be used, for example, as a cosmetic that is applied by spreading it on the skin, etc. Here, the cosmetic that is applied to the skin can also include what are called external skin preparations.

The formulation of the cosmetic composition of the present disclosure is not particularly limited, and examples thereof include liquid, emulsion, cream, gel, spray, and mousse. Here, in this disclosure, "spray" can include mist-type sprays, aerosol-type sprays, and the like.

The product form of the cosmetics disclosed herein is not particularly limited, and examples include facial cosmetics such as lotion, beauty serum, milky lotion, and pack; makeup cosmetics such as foundation; sunscreen cosmetics (sunscreen agents); body cosmetics; skin cleansing products such as makeup removers and body shampoos; hair cosmetics such as hair liquids, hair tonics, hair conditioners, shampoos, rinses, and hair growth products; ointments, etc.

<<Method for producing oil-in-water emulsion cosmetic>>
The oil-in-water emulsion cosmetic of the present disclosure can be prepared by known methods such as a dispersion method or an aggregation method.

The dispersion method is a method of breaking down the lumps of the dispersed phase into fine particles by mechanical force. Specifically, it is a method of emulsifying by utilizing the crushing force of an emulsifier. For example, a high-pressure emulsification method in which high shear force is applied using a high-pressure homogenizer can be mentioned as such a method.

The aggregation method is a colloid preparation method that utilizes surface chemical properties, in which a uniformly dissolved state is made into a supersaturated state by some means, resulting in the emergence of a dispersed phase. Specific methods include liquid crystal emulsification, HLB temperature emulsification, phase inversion emulsification, non-aqueous emulsification, and D-phase emulsification.

Among these methods, from the viewpoints of emulsion stability, feeling of crumbling, etc., it is advantageous to prepare the oil-in-water emulsion cosmetic of the present disclosure by the liquid crystal emulsification method. An interfacial film such as a gel film or liquid crystal film based on lamellar liquid crystals, etc., is likely to form near the interface of emulsion particles prepared by the liquid crystal emulsification method. As a result, aggregation and coalescence of emulsion particles is suppressed, emulsion stability is improved, and the strong interfacial film makes it easier to express a feeling of crumbling.

As a method for preparing the cosmetic composition of the present disclosure using the liquid crystal emulsification method, for example, the following method can be adopted. Note that the volatile acyclic silicone oil, the linear higher fatty acid having 16 or more carbon atoms, the monovalent higher alcohol, the nonionic surfactant, the salt-type or acid-type whitening agent and/or the salt-type or acid-type anti-inflammatory agent, the optional ingredients, etc. can be similarly used as those described above.

An oil phase solution is prepared by mixing a volatile acyclic silicone oil, a linear higher fatty acid having 16 or more carbon atoms, a monovalent higher alcohol, a nonionic surfactant, and any optional oil-soluble component while heating to about 70 to 90°C. Next, an aqueous phase solution is prepared by mixing water, a salt-type or acid-type whitening agent and/or a salt-type or acid-type anti-inflammatory agent, and any optional water-soluble component while heating to about 70 to 90°C. The oil phase solution is gradually added to this aqueous phase solution while stirring, and then cooled to room temperature, thereby preparing the oil-in-water emulsion cosmetic of the present disclosure.

In conventional liquid crystal emulsification methods, it has been confirmed that an interfacial film such as a gel film or liquid crystal film based on lamellar liquid crystals is formed around the emulsion particles when they are cooled to room temperature. Therefore, it is believed that such an interfacial film is also formed around the emulsion particles of the present disclosure at a similar stage.

The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these. In the following, unless otherwise specified, the blending amounts are shown in mass %.

Examples 1 to 3, Comparative Examples 1 to 4, and Reference Examples 1 to 3
The oil-in-water emulsion cosmetics obtained by the formulations shown in Tables 1 and 2 and the production methods shown below were subjected to the following evaluations, and the results are shown in Tables 1 and 2.

Evaluation Method
(Evaluation of Viscosity)
The viscosity of the cosmetic preparation was evaluated using a Brookfield viscometer (TVB-10 TVB viscometer, manufactured by Toki Sangyo Co., Ltd.) under conditions of rotor number L3, 30°C, 0.6 rpm and 12 rpm. The results and the viscosity ratios calculated from the results are summarized in the table. In the table, the viscosity measured at 0.6 rpm is represented as "V _{0.6 rpm} ," the viscosity measured at 12 rpm as "V _{12 rpm} ," and the viscosity ratio as "V _{0.6 rpm} /V _{12 rpm} ."

(Evaluation of emulsion stability)
The size of the oil droplets within one hour after the emulsion cosmetic preparation was prepared and the size of the oil droplets after storage at 50° C. for four weeks were observed using an optical microscope, and the emulsion stability was evaluated according to the following criteria:
A: There was almost no change in the size of the oil droplets.
B: The oil droplet size was slightly increased.
C: The oil droplet size was obviously increased, or the cosmetic separated.

<Production method of cosmetics>
Example 1
An oil-in-water emulsion cosmetic was produced by the liquid crystal emulsification method described below using the formulation shown in Table 1. Here, the numbers shown below correspond to the numbers indicating the names of the ingredients on the left side of the formulation in Table 1.

While heating to 70-90°C, oils No. 6-7 and No. 9-12 were mixed uniformly, and then nonionic surfactants No. 1 and No. 2, higher alcohols No. 3 and No. 4, and behenic acid, a linear higher fatty acid No. 5, were further mixed to prepare an oil phase solution.

Next, materials No. 13-20 and No. 22 were added to ion-exchanged water No. 23 while heating to 70-90°C, and mixed uniformly to prepare an aqueous phase solution.

While heating the aqueous phase solution to 70-90°C, the oil phase solution was gradually added and dispersed uniformly using a dispenser, after which it was cooled to room temperature to obtain the oil-in-water emulsion cosmetic of Example 1.

(Example 2, Comparative Examples 1 and 2, and Reference Example 1)
The oil-in-water emulsion cosmetics of Example 2, Comparative Examples 1 and 2, and Reference Example 1 were obtained in the same manner as in Example 1, except that the components and blending amounts of the oil phase solution and the aqueous phase solution were changed to the components and blending amounts shown in Table 1.

(Example 3, Comparative Examples 3-4, and Reference Examples 2-3)
The oil-in-water emulsion cosmetics of Example 3, Comparative Examples 3 and 4, and Reference Examples 2 and 3 were obtained in the same manner as in Example 1, except that the components and blending amounts of the oil phase solution and the aqueous phase solution were changed to the components and blending amounts shown in Table 2.

<result>
From the results of Reference Example 1, when an acid-type whitening agent and a salt-type whitening agent are not included, a viscosity ratio of 7.9 or more can be achieved, for example, by adjusting the mass ratio of the linear higher fatty acid to the monohydric higher alcohol. However, as can be seen from the results of Comparative Example 2, when an acid-type whitening agent is blended, a viscosity ratio of 7.9 or more cannot be achieved even if the mass ratio of the linear higher fatty acid to the higher alcohol is the same, and therefore the cosmetic of Comparative Example 2 did not feel crumbling even when applied to the skin and spread.

On the other hand, as is clear from the results of Examples 1 and 2, when a volatile non-cyclic silicone oil (dimethicone (1.5 cst)) was used as the oil, the cosmetics had excellent emulsion stability and achieved a viscosity ratio of 7.9 or more, even when an acid-type whitening agent and a salt-type whitening agent were blended, and it was confirmed that when these cosmetics were applied to the skin and spread, they exhibited a good feeling of crumbling.

In addition, as can be seen by comparing Examples 1 and 2 with Reference Example 1, it was found that the viscosity ratio of the emulsion cosmetic can be increased when a volatile acyclic silicone oil is used as the oil component.

<result>
As is clear from a comparison between Example 3 and Comparative Example 4, when a volatile acyclic silicone oil is used as the oil instead of a non-volatile acyclic silicone oil, good emulsion stability can be exhibited even when a whitening agent is blended, and a viscosity ratio of 7.9 or more can be achieved.

As can be seen by comparing the results of Reference Examples 2 and 3, as the proportion of polar oil in the oil increases, the viscosity ratio tends to decrease. The cosmetic of Comparative Example 3 does not contain polar oil, but even in this case, it was confirmed that if the oil does not contain a volatile acyclic silicone oil and contains an acid-type whitening agent, a viscosity ratio of 7.9 or more cannot be achieved.

Claims (8)

An oil-in-water emulsion cosmetic comprising: a dispersion medium containing at least one agent selected from a whitening agent and an anti-inflammatory agent, and water; and oil droplets dispersed in the dispersion medium,
The oil droplets contain an oil component, a linear higher fatty acid having 16 or more carbon atoms, a monohydric higher alcohol, and a nonionic surfactant,
The whitening agent includes at least one selected from a salt-type whitening agent and an acid-type whitening agent,
The anti-inflammatory agent includes at least one selected from a salt-type anti-inflammatory agent and an acid-type anti-inflammatory agent,
The oil component contains a volatile acyclic silicone oil, and the volatile acyclic silicone oil is contained in the oil component in an amount of 15% by mass or more and 40% by mass or less;
The content of the thickener is 0.01% by mass or less,
When a Brookfield viscometer is used in an atmosphere at 30° C., the viscosity ratio (V _{0.6 rpm} /V 12 rpm ) of the viscosity measured at 0.6 rpm (V _{0.6 rpm} ) to the viscosity measured at 12 rpm (V _{12 rpm} ) is 7.9 or more.
Oil-in-water emulsion cosmetic. The cosmetic according to claim 1, wherein the mass ratio of the linear higher fatty acid to the monohydric higher alcohol is 0.30 or more. The cosmetic preparation according to claim 1 or 2, wherein the linear higher fatty acid, the higher alcohol, and the nonionic surfactant form an interfacial film with the oil droplets in an atmosphere of 25°C. The cosmetic preparation according to any one of claims 1 to 3, wherein the linear higher fatty acid is at least one selected from stearic acid and behenic acid, and the higher alcohol is at least one selected from cetyl alcohol, isostearyl alcohol, stearyl alcohol, and behenyl alcohol. The cosmetic preparation according to any one of claims 1 to 4, wherein the salt-type whitening agent is at least one selected from ascorbic acid, tranexamic acid, glycyrrhizic acid, nicotinic acid, kojic acid, ellagic acid, 1-piperidinepropionic acid, 3-O-ethyl-L-ascorbic acid, and alkoxysalicylic acid, and the acid-type whitening agent is at least one selected from ascorbic acid, tranexamic acid, glycyrrhizic acid, nicotinic acid, kojic acid, ellagic acid, 1- piperidinepropionic acid, 3-O-ethyl-L-ascorbic acid, and alkoxysalicylic acid. The cosmetic preparation according to any one of claims 1 to 5 , wherein the anti-inflammatory agent is at least one selected from the group consisting of magnesium L-ascorbyl phosphate, dipotassium glycyrrhizinate, and ammonium glycyrrhizinate. The cosmetic preparation according to any one of claims 1 to 6, wherein at least one selected from the group consisting of the salt-type whitening agent, the acid-type whitening agent, the salt-type anti-inflammatory agent, and the acid - type anti-inflammatory agent is contained in an amount of 50 mass% or more based on the total amount of the whitening agent component and the anti-inflammatory agent component. The cosmetic preparation according to any one of claims 1 to 7 , further comprising a dihydric higher alcohol.