JP7689830B2 - health drinks - Google Patents

Description

The present invention relates to a health drink, in particular a health drink containing citric acid, sodium bicarbonate, and water-soluble silicic acid, and more preferably a health drink in which water-soluble silicic acid is mixed with dissolution water in which citric acid and sodium bicarbonate are dissolved (or citric acid and sodium bicarbonate are dissolved in modified water containing water-soluble silicic acid) and carbon dioxide gas is injected.

Ordinary carbonated drinks contain citric acid and fruit juice, and many also contain sweeteners, and are often only for personal preference. Many foreign carbonated drinks in particular are acidic, with a hydrogen ion concentration (pH) of around 2.0 to 2.5, and drinking them every day can cause ulcers in the stomach lining, raising concerns about their health hazards. These drinks are easy to drink and addictive, making them popular among the younger generation, but for those approaching working age, they affect the pathological stomach ulcer constitution that cannot keep up with changes in lifestyle, and are easily diagnosed with a history of stomach ulcers during stomach cancer screening.

To maintain a healthy constitution, it is necessary to prevent not only the above-mentioned gastrointestinal mucosal disorders, but also neurological disorders, lung diseases, hypersensitivity, liver diseases, kidney diseases, eye diseases, skin diseases, and other diseases such as diabetes and immune diseases. In order to protect against health problems caused by imbalanced lifestyle habits, there is a demand for health-conscious beverages that can be consumed on a daily basis.

Various minerals are necessary to maintain health, and silicon has been attracting attention in recent years. Silicon is not originally included in the 16 essential minerals in Japan, but in Europe and the US, including Germany, it is ranked fourth and is commonly used to strengthen bone cells in young children. In Japan, nanoparticle chemistry began to develop about 15 years ago with the advancement of analytical science, and with the expansion of nanotechnology, the recognition of silicic acid science has led to its use in the health industry.

In light of this, beverages containing silicon have been developed, and for example, beverages with product names such as "Nomu Silica" are on the market. In addition, the following Patent Document 1 discloses drinking water in which a colorless, odorless, tasteless, and highly pure (concentrated) silicon liquid is mixed into the drinking water.

JP 2012-44980 A

Silicon exists in the form of water-insoluble silica ( _SiO2 ) and water-soluble silicic acid ( _SiO4 ), but it is silicic acid that is necessary for maintaining human health, and silica is a substance that causes scale adhesion. In addition, silicic acid is mainly absorbed by aquaporins (cell membranes) and Peyer's patches in the intestines, but the absorption efficiency varies greatly depending on the size of the silicic acid and the pH of the solution, and there was a problem that silicic acid could not be efficiently absorbed into the body unless the size of the silicic acid was properly managed.

The present invention was made in consideration of the above problems, and its main objective is to provide a health drink that allows silicic acid to be efficiently absorbed into the body.

One aspect of the present invention is a health drink containing citric acid as an organic acid, sodium hydrogen carbonate as a bicarbonate, and water-soluble silicic acid, wherein the water -soluble silicic acid forms colloidal particles, and the health drink contains the colloidal particles having a size of 100 nm or less .

The present invention provides a health drink that allows silicic acid to be efficiently absorbed into the body, enables physical condition management that is essential for maintaining a healthy lifestyle, and has no adverse effects on the digestive system or mental state even if consumed regularly, truly contributing to good health.

The reason is that the health drink is produced by mixing water-soluble silicic acid of a certain size or less extracted from hot spring water or groundwater, etc., with dissolution water in which citric acid as an organic acid and sodium bicarbonate as a bicarbonate that exhibits good buffering capacity (buffer properties) against citric acid are dissolved, and carbon dioxide gas is injected as necessary. Alternatively, the health drink is produced by dissolving citric acid as an organic acid and sodium bicarbonate as a bicarbonate in modified water containing water-soluble silicic acid of a certain size or less, and injecting carbon dioxide gas as necessary.

FIG. 1 is a graph showing the correlation between the size of colloidal particles made of water-soluble silicic acid and their absorption efficiency into the body. FIG. 1 shows the analysis results of a conventional beverage (drinkable silica), where (a) is a distribution diagram of nanoparticles and (b) is the NANOSIGHT analysis results. FIG. 1 shows the analysis results of a conventional beverage (Perrier France), where (a) is a distribution map of nanoparticles and (b) is the NANOSIGHT analysis results. FIG. 1 shows the analysis results of a health drink (sparkling SiO ₄ bicarbonate) containing citric acid, sodium bicarbonate, and water-soluble silicic acid of the present invention, (a) being a distribution diagram of nanoparticles, and (b) being the NANOSIGHT analysis results.

Czech Hot Spring Colonnade: Vridelni Kolonada is known as the birthplace of drinking spring water. In this birthplace of drinking spring water, there is a belief that "it is a more valuable way to improve your health than eating vegetables," and all the water that has been highly valued for drinking is high-quality carbonated spring water, a historical custom dating back to 498.

Also, in the late 18th century, Carlsbad physician David Becher discovered carbon dioxide in the waters off Karlovy Vary and recommended that his patients drink mineral waters directly from hot springs, where the carbon dioxide influence is strongest.

After investigating various hot springs in Japan, the inventors of this application discovered that the water quality of Nagayu Hot Spring in Taketa City, Oita Prefecture is similar to that of the hot spring Colonnade in the Czech Republic, the birthplace of drinking hot springs. This Nagayu hot spring water is similar to the carbon dioxide in the ocean, has a neutral pH, and is mainly composed of bicarbonate ions. Clinical trials at Keio University and other institutions have shown that drinking the water is effective against various illnesses, including diabetes. Furthermore, the excellent buffering capacity of the bicarbonate ions neutralizes gastric acid and promotes bile secretion, which is said to stimulate the function of the stomach, intestines, liver, and pancreas.

The inventors of the present application therefore focused on the effects of bicarbonate and invented a carbonated beverage containing citric acid as an organic acid and sodium hydrogen carbonate (sodium bicarbonate) as a bicarbonate in their previous application (Patent No. 6698766). This carbonated beverage has the effect of suppressing blood sugar rise caused by intestinal flora, but in order to further enhance and improve functionality in cells, etc., they developed a health beverage that contains fine-sized silicon, which has excellent absorption ability from the intestinal environment into the body, as water-soluble silicic acid.

This silicic acid has moisturizing and skin-beautifying effects, as well as hair and nail growth and skin cell activation, and is often referred to as the "beauty mineral" for women. The effects of taking silicic acid have been announced, including preventing dementia and osteoporosis, producing skin, nails, and collagen, improving immune function, and maintaining the flexibility of blood vessels. Silicic acid is becoming increasingly important in building the foundations of health, and in the medical field it is used to treat cancer by emitting far-infrared radiation. Furthermore, the latest research has reported that a deficiency of silicic acid reduces the secretion of serotonin from the pineal gland, which activates the brain, leading to mental illnesses such as depression and anxiety.

As mentioned above, silicic acid is absorbed by Peyer's patches in the intestines. Furthermore, the absorption of silicic acid into the human body is similar in both plants and humans, with 0.01% of the silicon in the soil being transformed into silicic acid by root acid in plants, and the silicic acid moves toward the center of the root through the apoplast, which is made up of the intercellular spaces and cell walls of plant tissue. Talc (magnesium silicate, Mg ₂ SiO ₄ ), which is used as a pharmaceutical (tablet excipient/lubricant), is also further silicified by gastric acid, which helps maintain health. Furthermore, silicic acid colloid particles pass through human aquaporins and the intestinal wall (Peyer's patches) and are useful for detoxifying waste products in the blood.

The efficiency of absorption of this silicic acid into the body varies greatly depending on the size of the silicic acid and the pH of the solution. In particular, in order to efficiently absorb silicic acid into the body, it is important to reduce the size of colloidal particles made of water-soluble silicic acid. As presented in papers such as Henk-Maarten Laane 2018, The Effects of Foliar Sprays with Different Silicon Compounds, Plant, 7, 45; doi:10.3390/plants7020045, a size of 100 nm or less, especially 40 nm or less, which is the most commonly used size for foliar spraying, is also suitable for absorption from the human intestinal tract.

The inventors of the present application have therefore invented a health drink in which water-soluble silicic acid is mixed with dissolution water containing citric acid as an organic acid and sodium hydrogen carbonate (sodium bicarbonate) as a bicarbonate, as described in the above-mentioned prior application (Patent No. 6698766) (or citric acid and sodium hydrogen carbonate are dissolved in modified water containing water-soluble silicic acid), and carbon dioxide gas is injected as necessary.

The water-soluble silicic acid can be extracted, for example, using the functional water production device described in the inventor's other prior application (Patent No. 6328403), and by adjusting the size of the colloidal particles to 100 nm or less, particularly 40 nm or less, the efficiency of absorption into the body can be significantly improved. In addition, the citric acid (slightly acidic pH 4) and mixed carbonated water (pH 2.5) in this health drink help transform silicon into silicic acid.

The colloidal particles of the present invention may contain water-soluble silicic acid, and may include colloidal particles in which water-soluble silicic acid is aggregated, or colloidal particles in which water-soluble silicic acid is covalently bonded to other minerals. The size of the colloidal particles can be measured using a nanoparticle analyzer (e.g., LM10 model, manufactured by Malvern Instruments, UK and Quantum Design Japan, Ltd.).

To further explain the above-mentioned embodiment of the present invention in detail, a health drink according to one embodiment of the present invention will be described with reference to Figs. 1 to 4. Fig. 1 is a diagram showing the correlation between the size of colloidal particles made of water-soluble silicic acid and the absorption efficiency into the body. Figs. 2 and 3 are a distribution map of nanoparticles in a conventional drink and the results of NANOSIGHT analysis, and Fig. 4 is a distribution map of nanoparticles in a health drink containing citric acid, sodium bicarbonate, and water-soluble silicic acid according to the present invention and the results of NANOSIGHT analysis.

First, the citric acid-containing carbonated beverage described in the inventor's prior application (Patent No. 6698766) will be outlined. This citric acid-containing carbonated beverage is a carbonated beverage in which citric acid as an organic acid and sodium bicarbonate as a bicarbonate are dissolved in water, with 0.3 to 0.9 g of citric acid dissolved in 1,000 ml of the carbonated beverage, and the dissolution water is characterized by a ratio (mass ratio) of 2 to 8 parts sodium bicarbonate to 1 part citric acid, and by the fact that the dissolution water contains 1,000 to 10,000 ppm of carbon dioxide gas. Here, malic acid, succinic acid, fumaric acid, and the like are well known as organic acids and are inexpensive, but citric acid is the only organic acid that is favorably used in the present invention because it has the characteristics of good intestinal absorption of silicic acid and high health benefits.

This citric acid-containing carbonated beverage manufacturing device is, for example, a device in which a tank containing an acidic solution and a tank containing an alkaline solution are arranged adjacent to each other, and the tank containing the acidic solution contains an acidic solution in which a specified amount of citric acid is dissolved in a specified amount of water by mixing and stirring, and the tank containing the alkaline solution contains an alkaline solution in which a specified amount of baking soda is dissolved in a specified amount of water by mixing and stirring.

By using food additive grade citric acid to be mixed and dissolved in the tank containing the acidic solution and baking soda (sodium bicarbonate) to be mixed and dissolved in the tank containing the alkaline solution, the solution can be made suitable for drinking.

When mixing the acidic and alkaline solutions, the ratio of citric acid to baking soda should be 1:2-8 (mass ratio). If the ratio of baking soda is less than 2, the citric acid and sodium bicarbonate will undergo a vigorous neutralization reaction, generating carbon dioxide gas with bubbles large enough to be seen with the naked eye, with most of the carbon dioxide gas evaporating out of the liquid without dissolving in water. On the other hand, if the ratio of baking soda is more than 8, the solubility of the generated carbon dioxide gas in water will decrease.

Then, carbon dioxide gas at a concentration of 1,000 ppm to 10,000 ppm is injected into a solution containing citric acid and sodium bicarbonate in a ratio of 1:2 to 8 (by mass) to produce a citric acid-containing carbonated drink. If the amount of injection is less than 1,000 ppm, the total concentration of carbon dioxide gas dissolved in the carbonated drink water is insufficient to produce an effect of suppressing blood sugar rise, while if the amount of injection exceeds 10,000 ppm, the effect of suppressing blood sugar rise is reduced.

Next, we will outline the functional water production device described in another prior application (Patent No. 6328403) of the present inventor. This functional water production device is a method for producing functional water comprising the steps of: generating gas-liquid mixed water by nanobubbling ozone gas in water; and contacting the gas-liquid mixed water with natural minerals in a mineral component elution means to elute the mineral components of the natural minerals. The volume of the mineral elution means is set according to the residence time of the water supply of 2 to 5 minutes, the amount of natural minerals to be filled is adjusted according to the particle size or volume of the natural minerals based on the potential mineral components of the water and according to the target reference value, and the amount of ozone gas injected is controlled according to the temperature of the gas-liquid mixed water so that the oxidation-reduction potential of the gas-liquid mixed water is 650 mV.

This functional water production device is composed of a treated water inlet port for introducing treated water such as natural water, a first filtration filter for removing foreign matter from the treated water introduced from the treated water inlet port, a pressurized dissolution means for dissolving ozone gas into nanobubbles in the treated water that has passed through the first filtration filter to generate gas-liquid mixed water, a mineral elution means for contacting the gas-liquid mixed water generated by the pressurized dissolution means with natural minerals to elute the mineral components of the natural minerals, a second filtration filter for removing foreign matter from the gas-liquid mixed water discharged from the mineral elution means, a functional water discharge port for discharging the gas-liquid mixed water (functional water) that has passed through the second filtration filter, and connecting piping for connecting these components in series in this order.

The pressurized dissolution means generates gas-liquid mixed water by dissolving ozone gas in nanobubbles in the water to be treated, and includes an ozone generating means for generating ozone gas, a pressurizing pump for pressurizing the water to be treated, and a pressurized shear dissolution tank into which ozone gas and the pressurized water to be treated are introduced and which generates nanobubbles from the ozone gas and dissolves them in the water to be treated. The pressurized shear dissolution tank generates nanobubbles (fine bubbles) from ozone gas by the pressurized shear dissolution method and dissolves them in the water to be treated. The pressurized shear dissolution tank has an ozone gas inlet port for introducing the ozone gas generated by the ozone generating means, a pressurized water inlet port for introducing the water to be treated pressurized by the pressurizing pump, and a gas-liquid mixed water outlet port for discharging the gas-liquid mixed water generated by the pressurized shear dissolution tank. The nanobubbles generated by the pressurized shear dissolution layer have a diameter of 200 nm or less.

The mineral elution means is for eluting mineral components into the gas-liquid mixed water produced by the pressurized dissolution means, and has a mineral elution tank filled with natural minerals (natural ores containing silicates). This mineral elution tank has a gas-liquid mixed water inlet port that communicates with the gas-liquid mixed water outlet port of the pressurized shear dissolution tank, and an outlet port that outputs functional water produced by dissolving mineral components into the gas-liquid mixed water.

Both chemical weathering and physical weathering can be used to dissolve the mineral components of natural minerals into the gas-liquid mixed water (functional water) described above.

Chemical weathering is the dissolution of mineral components contained in natural minerals into gas-liquid mixed water by utilizing the ozone oxidation reaction caused by nanobubbled ozone gas contained in gas-liquid mixed water. The ozone oxidation reaction that brings about this chemical weathering is oxidative decomposition due to the strong oxidizing power of ozone itself in the acidic range (pH < 7), and in the alkaline range (pH > 7), the high concentration of hydroxide ions generates hydroxyl radicals with strong oxidizing power, and the oxidative decomposition is caused by the oxidizing power of these hydroxyl radicals. Here, whether an oxidizing agent is easily oxidized or reduced is expressed as the oxidation-reduction potential (ORP), and the more positive the value, the greater the oxidizing power, and the more negative the value, the greater the reducing power.

On the other hand, physical weathering refers to the physical behavior of nanobubbled ozone gas contained in gas-liquid mixed water, which physically wears down the particles of natural minerals and dissolves the mineral components contained in the natural minerals. The physical behavior of nanobubbled ozone gas that brings about this physical weathering is Brownian motion, and the speed of this Brownian motion depends on the temperature and viscosity of the liquid and the particle size of the nanobubbles. Therefore, if the temperature and viscosity of the liquid are the same, the speed of Brownian motion changes depending on the particle size of the nanobubbles. Specifically, the smaller the nanobubble diameter, the faster the Brownian motion speed, and the larger the nanobubble diameter, the slower the Brownian motion speed.

With the functional water production device configured in this way, the mineral elution means can elute mineral components from natural minerals (natural ores containing silicates) in the gas-liquid mixed water using both chemical weathering due to the oxidation reaction of ozone and physical weathering due to the behavior of nanobubbles.

This application utilizes the above two prior applications, and mixes water-soluble silicic acid with dissolution water in which citric acid as an organic acid and sodium bicarbonate as a bicarbonate are dissolved (or dissolves citric acid and sodium bicarbonate in modified water containing water-soluble silicic acid), and, if necessary, pressurizes carbon dioxide gas to produce a health drink, thereby adjusting the size of colloidal particles made of water-soluble silicic acid and increasing the efficiency of absorption of silicon and other minerals into the body. For example, nano-sized water-soluble silicic acid can be extracted using the functional water production device, and the pressure, content, and pH of the carbon dioxide gas can be adjusted during the production stage to promote the silicification of silicon and the refinement of silicic acid, thereby allowing the health drink to contain a large amount of water-soluble silicic acid of the desired colloidal particle size.

Table 1 shows the results of comparing the particle count and particle ratio of water-soluble silicic acid particles of each size in laboratory experiments (crushing with carbon dioxide) and in manufactured products (oxidation with citric acid and crushing with carbon dioxide). As can be seen from Table 1, during the manufacturing process, the water-soluble silicic acid particles undergo a turning effect due to oxidation with citric acid and crushing with carbon dioxide, turning them into particles ten times finer (see (1) in Table 1).

Next, we will explain the water-soluble silicic acid that is added to the dissolution water, in particular the multi-element covalent water-soluble silicic acid mineral that is combined with other minerals.

In silicate mineral solutions, which contain primordial materials from the Earth's formation period, there are phenomena that are considered to be unable to be explained by inorganic chemistry models alone. This is the existence of highly thermophilic bacteria such as Thermus and Hydrogenobacter in multi-element shared silicate minerals, and this phenomenon has been an obstacle to enabling the multi-purpose use of silicate mineral solutions. On the other hand, in reactions with an oxidation-reduction potential (ORP) of 650mV or higher after the ozone-nanobubble reaction using the functional water production device described above, no traces of microorganisms were found, and the multi-element shared minerals used in this invention have also been confirmed to have a microbial-hindering effect.

In the present invention, this mechanism is utilized, and the raw material for the multi-element shared silicate mineral solution is hot spring water that has been sterilized without heating by passing steam heated by underground magma through silicate minerals. Specifically, in the non-heating sterilization process, the water at the interface of the multi-element shared silicate mineral solution is alkaline (pH 8.5-9.0) regardless of the pH of the water inside, and a compound called M(OH)n is created on the metal surface that comes into contact with the water through a reduction action. In other words, through oxidation and reduction reactions under ozone oxidation heat and high pressure conditions, nano-sized (10-100 nm) is promoted, and the silicate is modified into metasilicic acid (H ₂ SiO ₃ ), metadisilicic acid (H ₂ Si ₂ O ₅ ), orthosilic acid (H ₄ SiO ₄ ), etc. This amplifies the highly active silicate _SiO4 group of 10 _nanometers or less, forming _hydrates of other divalent cations and trace metal ions such as _calcium silicate ( _Ca2SiO4 ), magnesium silicate ( _Mg2SiO4 ), and potassium silicate ( _K2SiO3 ), contributing to the supply of essential minerals to humans. It also contains sulfates necessary for human protein synthesis.

What is important here is that consumers understand that the more silicon SiO ₂ (silica) content there is, the better. However, it is silicic acid, not silica, that is necessary for maintaining human health, and silica is disliked in water-handling businesses as it is treated as garbage (scale buildup). Even when judged by environmental quantitative analysis, silicic acid > silica is necessary, and silicic acid drives the leading reaction. For example, the drug delivery action (hydroxyl ion) of water-soluble silicic acid SiO ₄ is used for the intravascular delivery effect of medicinal ingredients.

This article will provide a detailed description of the intravascular delivery effect of medicinal ingredients through the drug delivery action (hydroxyl ions) of water-soluble silicate _SiO4 . This treatment utilizes antibodies that specifically bind only to cancer cells, and the antibodies are attached with a substance (IR700) that undergoes a chemical reaction when exposed to near-infrared light, which is then injected intravenously into the body. The antibodies reach and bind to cancer cells, and when they are irradiated with near-infrared light, a chemical reaction occurs and the cancer cells are destroyed. Near-infrared light has a wavelength that is intermediate between visible light and infrared light. For treatment, near-infrared light with the shortest wavelength (700nm) and highest energy is used.

IR700 is a dye called phthalocyanine that has the ability to absorb near-infrared energy with a wavelength of 700 nm. The IR700 that is changed by this chemical reaction denatures the proteins bound to the antibodies that are irradiated onto the membranes of cancer cells, causing the cell membranes to lose their function, destroying the cancer cells in an extremely short time of 1 to 2 minutes. This treatment has almost no side effects and its safety has been confirmed.

First of all, antibodies do not bind to normal non-cancerous cells, so there is no harm in irradiating them with near-infrared light, and even cancer cells to which antibodies have bound will not be destroyed unless they are hit by this special near-infrared light. In other words, this is a highly selective treatment that has been garnering attention, as it only destroys cancer cells that have both bound to antibodies and been hit by light. Never before has there been such a highly selective cancer treatment.

This IR700 is a water-insoluble substance and does not enter the body, but by using silicic acid, it becomes water-soluble, and is excreted in the urine within one day after surgery, so it is also harmless to humans.

In this way, by using water-soluble silicic acid _SiO4 instead of silicon _SiO2 (silica), substances that do not dissolve in water can also be taken into the body, which can contribute to the supply of essential human minerals such as calcium, magnesium, and potassium.

As shown in the table below, the methods of producing water-soluble silicic acid can be broadly divided into (1) those derived from silicate minerals (crystal, quartz, etc.) (Patent No. 4564086: porous spherical metasilicic acid colloid solution), (2) drinking liquid (bottled water) made by ultra-finely grinding biotite porphyry or granite using strong acids such as hydrochloric acid or sulfuric acid, and (3) those called water-soluble silicic acid extracted from rice husks. On the other hand, (4) there is a household item that modifies tap water with silicic acid solution (0.4 ppm/hr) eluted from Amagi anti-fire stone, but aluminum is detected and it is a drawback that it may induce Alzheimer's. There is also (5) drinking silica (silica 97 ppm - produced in Kobayashi City, Miyazaki Prefecture), etc. In addition, (6) is a modified silicate mineral water (hot spring water), which is the primary raw material used in the health drink of this invention, and is safe because it is carried out through mechanical engineering reaction rate control at the natural resource modification stage, including virus inactivation and bacteria sterilization.

If the purpose is to drink water to improve immunity and maintain health, the strongly alkaline (1) and (3) are unsuitable. (2) is rich in metallic minerals but has low levels of silicic acid. (4) is unsuitable for use by the general public because aluminum leaches out of the material. (5) is commercially available drinking water, but care must be taken to avoid problems caused by excessive drinking (kidney stones, etc.). (6) is a reformed liquid that can be used for multiple purposes, and is made using a safe natural resource reforming device.

Next, the components of the commercially available drinking water "Product name: Nomu Silica" in Table 2 (5), the modified water (referred to as hot spring modified water) obtained by modifying silicate mineral water (hot spring water) in Table 2 (6), and the health drink of the present invention (referred to as added SiO ₄ bicarbonate) obtained by dissolving citric acid as an organic acid and sodium bicarbonate as a bicarbonate in the hot spring modified water are compared.

In the environmental quantitative analysis of commercially available drinking water, the silicic acid content was 45 mg and the silica content was 77 mg, giving a silicic acid ratio (silicic acid/silica) of 45 mg/77 mg = 58%. On the other hand, in the case of hot spring modified water, the silicic acid content was 210 mg and the silica content was 150 mg, giving a silicic acid ratio of 210/150 = 140%. Here, as mentioned above, the silicic acid ratio is required to be 100% or more (silicic acid ≧ silica), so it can be seen that the hot spring modified water used in the health drink of this invention is superior to commercially available drinking water. Incidentally, the silicic acid ratio of Misasa Onsen is 22/60 silica = 37%. The silicic acid ratio of Tamatsukuri Onsen is 29/82 silica = 36%.

In addition, the viscosity of the primary raw material (modified hot spring water) is 0.825 cP, whereas that of ordinary tap water is 1.0 cP, and the health drink of the present invention made using this modified hot spring water has a viscosity of 0.9 cP. Therefore, the health drink of the present invention has excellent particle number as well as intestinal penetration and passage (absorption by aquaporins and Peyer's patches), which is the basis for regular metabolic action.

In addition, the calcium, magnesium and potassium contained in the hot spring water used in the health drink of the present invention, when the value when divided by the silica concentration is 1.0 or less, are sufficiently covalently bonded to the highly active silicic acid _SiO4 group described above, and therefore play a role in multi-element sharing.

This multi-element covalent silicate is representative of the hydration properties of the structure-forming ions, and the zeta potential of the resulting colloidal particles with increasing water-soluble silicate _SiO4 is negative in all entrapped minerals.

The amorphization of this multi-element covalent silicate can be confirmed by the Brownian motion of colloidal particles, but this is limited to particle motion approaching the inorganic 10 nanometer size, and the nano-size measurement range is only about 0.01 percent. In addition, somatocytes, which are called inorganic microscopic life forms, are also visible in the measurements. The nanoparticle analyzer used is the LM10 model from Malvern, UK, and Japan Quantum Design Co., Ltd.

Figure 1 shows the correlation between the size of colloidal particles made of water-soluble silicic acid and the efficiency of absorption into the body. Water-soluble silicic acid can be detected as colloidal particles from 8 nm, so 10 nm or more is shown. As shown in Figure 1, as the size of colloidal particles increases, they become more difficult to be absorbed into the human body, and the absorption efficiency decreases. Thus, in order to efficiently absorb silicic acid into the human body, it is preferable for the colloidal particles to be small, but it is not easy to create fine colloidal particles. Therefore, considering absorption through human aquaporins and the intestinal wall (Peyer's patches), it can be said that a size of 100 nm or less is preferable, especially 40 nm or less, which is the most commonly used size for foliar spray.

Next, referring to Figures 2 to 4, the size of water-soluble silicic acid in the commercially available drinking water "Product name: Drinking Silica" and "Product name: Perrier France" is compared with that of the health drink "Product name: Sparkling SiO ₄ Bicarbonate" containing citric acid, sodium bicarbonate, and water-soluble silicic acid of the present invention. The horizontal axis of the graph (a) is the size of colloidal particles (nm), and the vertical axis is the particle size (au), and the smaller the particle size distribution, the more microcolloids there are, and the more particles there are below the measurement limit. The horizontal axis of the graph (b) is the size of colloidal particles (nm), and the vertical axis is the concentration (particles/ml), and the larger the value on the left side, the more microcolloids there are.

Figure 2 shows the analysis results for "Nomu Silica," where (a) is the nanoparticle distribution map and (b) is the NANOSIGHT analysis result. The product label states that the silica content is 97 mg/l and the number of nanoparticles is 580 million/ml, but it can be seen that there is an insufficient number of nanoparticles of a size of 40 nm or less (the number within the area indicated by the dashed line in the figure), which are highly absorbable by the body. The pH is also 7.

Figure 3 shows the analysis results for "Perrier France," where (a) is the nanoparticle distribution map and (b) is the NANOSIGHT analysis result. The nanoparticle count is 560 million/ml, but as with the above, it can be seen that there is a shortage of nanoparticles of a size of 40 nm or less (the number within the area indicated by the dashed line in the figure), which are highly absorbable in the body. The pH is also 8.

FIG. 4 shows the analysis results of "Sparkling SiO ₄ Bicarbonate", (a) is a distribution diagram of nanoparticles, and (b) is the NANOSIGHT analysis result. The number of particles is 208 million/ml, but what should be emphasized is not the silicon content (ppm) but the size of nanoparticles that are excellent in human absorption. As shown by the dashed line in the figure, it can be seen that there are many silicic acids of 100 nm or less, especially 40 nm or less, which are excellent in body absorption. Table 4 shows the integral value of the concentration distribution in FIG. 4(b), and shows the number of particles, cumulative number of particles, particle ratio%, and cumulative particle ratio% in each size range (0.5 nm pitch). From Table 4, the particle ratio of 100 nm or less is 75.29%, and the number of particles is 105 million/ml. In addition, the particle ratio of 40 nm or less is 7.02%, and the number of particles is 0.098 million/ml.

Sparkling SiO ₄ bicarbonate 500cc contains well-balanced mineral elements, with sodium: 9.0mg/0.5l, sulfate: 8.6mg/0.5l, magnesium: 6.8mg/l, silicic acid: 4.2mg/l, potassium: 1.84mg/l, calcium: 0.08mg/l, boron: 0.036mg/l, etc. covalently bonded with silicic acid to form multi-element covalent water-soluble silicic acid minerals. The 140-160nm range in Table 4 is considered to be the particle zone where minerals other than silicon (sodium, sulfate, magnesium, potassium, calcium) are covalently bonded with silicic acid.

As explained above, by mixing water-soluble silicic acid with dissolution water in which citric acid as an organic acid and sodium bicarbonate as a bicarbonate are dissolved (or by dissolving citric acid as an organic acid and sodium bicarbonate as a bicarbonate in modified water containing water-soluble silicic acid), and injecting carbon dioxide gas as necessary to produce a health drink, silicic acid can be efficiently absorbed into the body.

The health drink of the present invention is a mixture of citric acid and bicarbonate in a solution to which a certain amount of water-soluble minerals, which are at the center of a multi-element sharing system, unlike silicon or silica and silicic acid as generally described, have been added, making it an excellent health drink that efficiently exerts a radical scavenging and suppressing effect against the generation of radicals in the body.

The present invention can be understood in a familiar way because the antioxidant effect in the body makes you less likely to get tired. For example, when you have a cold, you don't have a fever, but sneeze and cough, and the next day you're cured. If you drink the health drink of the present invention every morning, you will urinate two hours later, and you will definitely feel regularity. Also, if you drink it before meals, it has a good insulin effect for diabetes, and you can maintain good health. You can feel the effects, such as improvements in regular blood tests. The health drink of the present invention is a functional food, and the need for multi-element shared minerals was also reported in the NHK news program "Gatten" broadcast on September 4, 2019, which said, "The human body needs 60 types of metal minerals."

In addition, immediately after drinking the health drink of the present invention, the strongly acidic gastric juices and the health drink neutralize to bring the pH to a weakly acidic range, and the carbon dioxide gas is released by the burping action, and the pH becomes neutral due to the high buffering properties of sodium bicarbonate and citric acid, exerting a buffering effect that also enhances the absorbability of silicic acid in the intestines. With a strong carbon dioxide gas concentration, it exerts properties that are completely different from strongly acidic products with a pH of about 2.0 to 4.8, such as those called "strong carbonated drinks." In this way, because the health drink of the present invention has a pH adjusted to 5.5 to 8.3, it is digested with gastric acid and transported to the intestines without damaging the stomach wall itself, and can achieve effects such as suppressing blood sugar rise.

The present invention is not limited to the above-mentioned embodiment, and the configuration can be modified as appropriate without departing from the spirit of the present invention.

For example, in the above embodiment, a health drink was prepared by adding water-soluble silicic acid to a dissolution water containing citric acid as an organic acid and sodium bicarbonate as a bicarbonate, as described in the inventor's prior application (Patent No. 6698766), but a health drink may be prepared by adding water-soluble silicic acid to a solution having the same components as the dissolution water. Also, in the above embodiment, a health drink was prepared by dissolving citric acid as an organic acid and sodium bicarbonate as a bicarbonate in hot spring modified water containing water-soluble silicic acid, but a health drink may be prepared by dissolving citric acid and sodium bicarbonate in modified water having the same components as the hot spring modified water (for example, modified water modified from spring groundwater).

In the above examples, water-soluble silicic acid was extracted from hot spring water using the functional water production device described in another prior application of the present inventor (Patent No. 6328403), but as long as water-soluble silicic acid can be extracted by a method other than chemical synthesis, there are no particular limitations on the production device or the solution used to extract water-soluble silicic acid.

The present invention can be used for health drinks containing organic acids, bicarbonates, and water-soluble silicic acid.

Claims (5)

A health drink containing citric acid as an organic acid, sodium hydrogen carbonate as a bicarbonate, and water-soluble silicic acid ,
The water-soluble silicic acid forms colloidal particles, and the health beverage contains the colloidal particles having a size of 100 nm or less.
A health drink characterized by The particle ratio of the colloidal particles having a size of 100 nm or less is 75% or more, or the particle number is 100 million particles/ml or more.
2. The health drink according to claim 1. The particle ratio of the colloidal particles having a size of 40 nm or less is 7% or more, or the particle number is 90 million particles/ml or more.
3. The health drink according to claim 1 or 2 . The health drink contains minerals other than silicon, and the water-soluble silicic acid is covalently bonded to the minerals to form the colloidal particles.
4. The health drink according to claim 1, wherein the beverage is a beverage containing a volatile organic compound. The health drink contains water-insoluble silica and the water-soluble silicic acid as silicon, and the weight ratio of the water-soluble silicic acid to the water-insoluble silica is 100% or more.
5. The health drink according to claim 1 ,

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