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JP7749366B2 - How to evaluate chapped lips - Google Patents
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JP7749366B2 - How to evaluate chapped lips - Google Patents

How to evaluate chapped lips

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JP7749366B2
JP7749366B2 JP2021116743A JP2021116743A JP7749366B2 JP 7749366 B2 JP7749366 B2 JP 7749366B2 JP 2021116743 A JP2021116743 A JP 2021116743A JP 2021116743 A JP2021116743 A JP 2021116743A JP 7749366 B2 JP7749366 B2 JP 7749366B2
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lips
brightness
threshold
elasticity
area ratio
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JP2023012954A (en
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史仁 宇田川
睦 安部
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Kose Corp
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Description

本発明は、口唇荒れの評価方法に関する。 The present invention relates to a method for evaluating chapped lips.

口唇は、個人の印象に大きく寄与し、日常生活、美容において重視された部位であるが、バリア機能が低く、乾燥や皮剥けといった荒れ症状が頻出する部位である。 Lips contribute greatly to a person's impression and are an important part of daily life and beauty, but they have a weak barrier function and are prone to roughness such as dryness and peeling.

従来、口唇荒れを評価する方法として、非特許文献1~3に記載の方法が知られている。 Conventionally, methods for evaluating chapped lips are known, such as those described in Non-Patent Documents 1 to 3.

姫野達也ら著、「口唇荒れに関する新たな評価方法の開発」、第56回SCCJ研究討論会講演要旨集、2005年、p20-23Tatsuya Himeno et al., "Development of a new evaluation method for chapped lips," Abstracts of the 56th SCCJ Research Symposium, 2005, pp. 20-23 上田郁子ら著、「口唇荒れと口唇角層細胞のカルボニル化修飾タンパク質に関する研究」、第62回SCCJ討論会要旨集、2008年、p21-24Ikuko Ueda et al., "Research on Chapped Lips and Carbonylation-Modified Proteins in Lip Corneal Cells," Abstracts of the 62nd SCCJ Symposium, 2008, pp. 21-24 友木依里子ら著、「口唇乾燥状態の客観的評価法とその要因について」、日本香粧品学会誌、2018年、Vol.42、No.1、p1-8"Objective evaluation method for dry lips and its causes," by Eriko Tomoki et al., Journal of the Japanese Society of Cosmetic Chemistry, 2018, Vol. 42, No. 1, pp. 1-8

荒れの軽減にはリップクリーム等が使用されるが、荒れの改善効果に満足が得られない例がみられる。本発明者らは、荒れの状態を細かく分類することで、各状態に適した改善方法を提案できるか検討するため、荒れの状態についてさらに詳細に検討を進めた。そして、皮剥けの無い、外観がきれいな口唇においても、荒れの状態がいくつか分類できることを見出した。そして、非特許文献1~3に記載の従来の方法は、皮剥けの無い口唇の荒れの分類として適さないことを見出した。 Lip balms and other products are used to reduce chapped lips, but there are cases where the improvement effect is not satisfactory. The inventors conducted a more detailed study of chapped lips to see if a more detailed classification of chapped lips would allow them to propose an appropriate improvement method for each condition. They discovered that even lips that are free of peeling and have a clean appearance can be classified into several types of chapped lips. They also found that the conventional methods described in Non-Patent Documents 1 to 3 are not suitable for classifying chapped lips without peeling.

従って、本発明の目的は、皮剥けの無い、外観がきれいな口唇の荒れ状態を分類する方法を提供することにある。 Accordingly, the object of the present invention is to provide a method for classifying the condition of chapped lips that is free of peeling and has a clean appearance.

すなわち、本発明は以下の通りである。
[1]
可視光照射画像から口唇の皮剥けの有無を評価するステップ1と、
紫外線照射画像から口唇の輝度値を評価するステップ2と、
を有することを特徴とする口唇荒れの評価方法。
[2]
前記ステップ1の後に前記ステップ2を行う、[1]に記載の口唇荒れの評価方法。
[3]
前記ステップ2において下唇の紫外線照射画像を用いる、[1]又は[2]に記載の口唇荒れの評価方法。
[4]
前記紫外線照射画像が365nmを含む紫外線を照射して取得した画像である、[1]~[3]のいずれかに記載の口唇荒れの評価方法。
[5]
前記ステップ2において、前記ステップ1において皮剥けが無かった被験者の下唇の前記紫外線照射画像から輝度値を評価する、[1]~[4]のいずれかに記載の口唇荒れの評価方法。
[6]
前記ステップ2において、前記下唇の全面積に対する輝度閾値以上となる輝度値を示す面積の割合である輝度面積割合を用いて口唇の輝度値を評価する、[5]に記載の口唇荒れの評価方法。
[7]
前記ステップ2において、輝度面積割合閾値に対する前記輝度面積割合の大きさから口唇の輝度値を評価する、[6]に記載の口唇荒れの評価方法。
[8]
前記輝度閾値が70~80の範囲のいずれか1点である、[6]又は[7]に記載の口唇荒れの評価方法。
[9]
前記輝度閾値が75であり、前記輝度面積割合閾値が5~15%の範囲のいずれか1点である、[6]~[8]のいずれかに記載の口唇荒れの評価方法。
[10]
[6]又は[7]に記載の口唇荒れの評価方法の輝度閾値を決定する方法。
[11]
[7]に記載の口唇荒れの評価方法の輝度面積割合閾値を決定する方法。
[12]
[1]~[11]のいずれかに記載の口唇荒れの評価方法を含む、口唇のカウンセリング方法。
[13]
[1]~[11]のいずれかに記載の口唇荒れの評価方法に続いて、口唇化粧料および/または外用剤を推奨することを含む、[12]に記載の口唇のカウンセリング方法。
That is, the present invention is as follows.
[1]
Step 1: Evaluating the presence or absence of lip peeling from the visible light irradiation image;
Step 2: Evaluating the luminance value of the lips from the UV-illuminated image;
A method for evaluating chapped lips, comprising:
[2]
The method for evaluating chapped lips according to [1], wherein step 2 is carried out after step 1.
[3]
The method for evaluating chapped lips according to [1] or [2], wherein an image of the lower lip exposed to ultraviolet light is used in step 2.
[4]
The method for evaluating chapped lips according to any one of [1] to [3], wherein the ultraviolet irradiation image is an image obtained by irradiating ultraviolet light containing 365 nm light.
[5]
The method for evaluating chapped lips according to any one of [1] to [4], wherein in step 2, the brightness value is evaluated from the ultraviolet irradiation image of the lower lip of the subject who did not have peeling in step 1.
[6]
The method for evaluating chapped lips described in [5], wherein in step 2, the luminance value of the lips is evaluated using a luminance area ratio, which is the ratio of the area showing a luminance value equal to or greater than a luminance threshold to the total area of the lower lip.
[7]
The method for evaluating chapped lips according to [6], wherein in step 2, the luminance value of the lips is evaluated based on the magnitude of the luminance area ratio relative to a luminance area ratio threshold.
[8]
The method for evaluating chapped lips according to [6] or [7], wherein the brightness threshold is any one point in a range of 70 to 80.
[9]
The method for evaluating chapped lips according to any one of [6] to [8], wherein the brightness threshold is 75 and the brightness area ratio threshold is any one point in a range of 5 to 15%.
[10]
A method for determining a brightness threshold value for the method for evaluating chapped lips according to [6] or [7].
[11]
A method for determining a luminance area ratio threshold for the lip chapped mouth evaluation method described in [7].
[12]
A lip counseling method comprising the method for evaluating chapped lips according to any one of [1] to [11].
[13]
The lip counseling method according to [12], which comprises recommending a lip cosmetic and/or topical preparation following the method for evaluating chapped lips according to any one of [1] to [11].

本発明によれば、皮剥けの無い、外観がきれいな口唇の荒れ状態を分類する方法を提供することができる。 The present invention provides a method for classifying the condition of chapped lips that are free of peeling and have a clean appearance.

本実施形態の口唇荒れの評価方法の一例を示す概略図である。また、実施例1の口唇荒れ評価の説明図である。1 is a schematic diagram showing an example of a method for evaluating chapped lips according to the present embodiment, and is an explanatory diagram of the evaluation of chapped lips in Example 1. ステップ1における皮剥けの有無の評価を説明する図である。FIG. 1 is a diagram illustrating the evaluation of the presence or absence of peeling in step 1. ステップ2における紫外線照射画像から口唇の輝度値の評価を説明する図である。(a)は取得した紫外線照射画像、(b)は下唇を切り取った画像、(c)は輝度閾値で二値化した画像である。10A and 10B are diagrams illustrating evaluation of the luminance value of the lips from the ultraviolet irradiation image in step 2. (a) is the acquired ultraviolet irradiation image, (b) is an image with the lower lip cut out, and (c) is an image binarized using a luminance threshold value. ステップ2における紫外線照射画像から口唇の輝度値の評価を説明する図である。(a)は対象者の口唇の可視光照射画像、(b)は紫外線照射画像、(c)は輝度閾値で二値化した画像である。10A and 10B are diagrams illustrating evaluation of the luminance value of lips from an ultraviolet light irradiation image in step 2. (a) is an image of the subject's lips irradiated with visible light, (b) is an image irradiated with ultraviolet light, and (c) is an image binarized using a luminance threshold value. ステップ2における紫外線照射画像から口唇の輝度値の評価を説明する図である。(a)は対象者の口唇の可視光照射画像、(b)は紫外線照射画像、(c)は輝度閾値で二値化した画像である。10A and 10B are diagrams illustrating evaluation of the luminance value of lips from an ultraviolet light irradiation image in step 2. (a) is an image of the subject's lips irradiated with visible light, (b) is an image irradiated with ultraviolet light, and (c) is an image binarized using a luminance threshold value. 実施例2の結果を示す表である。輝度閾値及び輝度面積割合閾値と、専門評価者による評価との合致率を表す表である。10 is a table showing the results of Example 2. It is a table showing the agreement rate between the luminance threshold and the luminance area ratio threshold and the evaluation by the expert evaluator. 実施例3の結果を示す表である。1 is a table showing the results of Example 3. 実施例6の結果を示す表である。1 is a table showing the results of Example 6.

本実施形態の口唇荒れの評価方法は、可視光照射画像から口唇の皮剥けの有無を評価するステップ1と、紫外線照射画像から口唇の輝度値を評価するステップ2と、を有する。本実施形態の評価方法は、口唇のパラメータ測定等の他のステップをさらに含んでいてもよい。 The method for evaluating chapped lips of this embodiment includes step 1, which evaluates the presence or absence of chapped lips from an image illuminated with visible light, and step 2, which evaluates the luminance value of the lips from an image illuminated with ultraviolet light. The evaluation method of this embodiment may further include other steps, such as measuring lip parameters.

上記ステップ1と上記ステップ2との順は特に限定されないが、皮剥けの有無を判断する解析は、ステップ1のほうが容易である観点から、ステップ1の後にステップ2を行うことが好ましい。 The order of Step 1 and Step 2 above is not particularly limited, but it is preferable to perform Step 2 after Step 1, as the analysis to determine whether or not the skin has peeled is easier in Step 1.

(ステップ1)
上記ステップ1では、可視光照射画像から口唇の皮剥けの有無を判定する。なお、口唇の皮剥けは、目視による判定と併用してもよい。
(Step 1)
In the above step 1, the presence or absence of chapped lips is determined from the visible light irradiation image. Note that the presence or absence of chapped lips may be determined in addition to visual determination.

上記ステップ1において、上記可視光照射画像により、口唇に皮剥けが1か所でも認められれば皮剥け有りと判定する(図2)。
通常、口唇は、古い角質細胞が剥離せずに残存して肥厚した部分が生じ、肥厚した部分が剥ける。皮剥けは、完全に皮が剥けている状態、端のみが剥けている状態等を含み、口唇表面上の皮が、一部でも剥けている状態をいう。図2の3つの円状の囲み線において、中央の大きな円状の囲み線内の部分は皮が完全に剥けている部分であり、右側の小さな円状の囲み線内部分は端のみが剥けている部分である。
皮剥けの判定を行う判定者は、例えば、口唇の専門評価者であってもよい。例えば、3名の評価者(好ましくは専門評価者)で評価を行い、全員が皮剥け有りと判定した場合を皮剥け有りとしてよい。
In step 1, if peeling is found in even one spot on the lip in the visible light irradiation image, it is determined that peeling is present (FIG. 2).
Normally, old keratinocytes remain on the lips without peeling, resulting in thickened areas, which then peel. Peeling refers to a state in which even a portion of the skin on the lip surface has peeled, including complete peeling and peeling only at the edges. In the three circular lines in Figure 2, the area within the large central circular line is the area where the skin has completely peeled, and the area within the small circular line on the right is the area where only the edges have peeled.
The assessor who judges whether or not peeling occurs may be, for example, a specialist assessor of lips. For example, when the assessment is performed by three assessors (preferably specialist assessors), peeling may be determined to occur if all assessors judge that peeling occurs.

上記可視光照射画像は、口唇荒れを評価できる画像であれば特に限定されず、適度な照明のもとでデジタルカメラ等を用いて撮影した画像としてよい。
上記可視光照射画像は、後述の紫外線照射画像と照明条件を変えること以外は、同じ条件で撮影した画像を用いてよい。例えば、異なる機器を用いて可視光照射画像と紫外線照射画像とを取得してもよいし、同一の機器(例えば、VISIA-CR(Canfield Scientific社製))を用いて取得してもよい。
The visible light irradiation image is not particularly limited as long as it is an image that can be used to evaluate chapped lips, and may be an image taken using a digital camera or the like under appropriate lighting.
The visible light irradiation image may be an image captured under the same conditions as the ultraviolet light irradiation image described below, except for changing the illumination conditions. For example, the visible light irradiation image and the ultraviolet light irradiation image may be acquired using different devices, or may be acquired using the same device (e.g., VISIA-CR (manufactured by Canfield Scientific)).

撮影時の明るさとしては、500~2000ルクスの照度で撮影することが好ましい。また、画像は、300万画素以上(好ましくは1500万画素以上)の画像(例えば、横方向に2736画素以上、縦方向に1824画素以上の画像において、画像の面積100%に対して顔が50~90%(好ましくは、60~80%)を占める画像)であることが好ましい。
複数の対象者を評価する場合、全対象者の画像は、同じ条件で撮影した画像であることが好ましい。
The brightness during shooting is preferably 500 to 2000 lux. The image is preferably an image of 3 million pixels or more (preferably 15 million pixels or more) (for example, an image of 2736 pixels or more horizontally and 1824 pixels or more vertically, with the face occupying 50 to 90% (preferably 60 to 80%) of the 100% image area).
When multiple subjects are evaluated, it is preferable that the images of all subjects are taken under the same conditions.

上記可視光照射画像としては、特に限定されず、例えば、過去に撮影した画像、評価する場所と異なる場所で撮影した画像、複数人が写った画像等を使用することもできる。 The visible light irradiation image is not particularly limited, and can be, for example, an image taken in the past, an image taken at a location different from the location being evaluated, an image containing multiple people, etc.

対象者としては、ヒトであれば特に限定されず、男性、女性を問わない。また、対象者の年齢も特に限定されない。 Subjects are not particularly limited as long as they are humans, and can be male or female. There are also no particular limitations on the age of the subject.

(ステップ2)
上記ステップ2は、紫外線照射画像から口唇の輝度値を評価する。上記ステップ2は、上記ステップ1において、皮剥け無しと判定された対象者に対して行ってよい。
紫外線照射画像において、輝度が高い箇所は口唇が荒れており、輝度が低い箇所は口唇荒れがないと評価することができる。
(Step 2)
In step 2, the luminance value of the lips is evaluated from the ultraviolet light irradiation image. Step 2 may be performed on subjects who are determined not to have peeling in step 1.
In the ultraviolet irradiation image, it can be evaluated that areas with high brightness indicate chapped lips, and areas with low brightness indicate no chapped lips.

上記紫外線照射画像は、適度な紫外線照射下で撮影した画像としてよい。上記紫外線としては、400nm以下の波長を少なくとも含む紫外線であることが好ましく、365nmの波長を含む紫外線であることがより好ましい。 The ultraviolet irradiation image may be an image captured under moderate ultraviolet irradiation. The ultraviolet light preferably contains at least a wavelength of 400 nm or less, and more preferably contains a wavelength of 365 nm.

上記ステップ2は、口唇荒れは下唇に特異的に発生するとの報告もあり、より正確な分類が可能となる観点から、下唇の紫外線照射画像を用いることが好ましい。 In step 2 above, it has been reported that chapped lips occur specifically on the lower lip, so it is preferable to use an ultraviolet image of the lower lip to enable more accurate classification.

上記輝度値は、紫外線照射画像を256階調の画像に変換して求めることができる。具体的には、後述の実施例に記載の方法で求めることができる。 The above brightness values can be determined by converting the UV-irradiated image into a 256-level image. Specifically, they can be determined using the method described in the Examples below.

紫外線照射画像の撮像時に、輝度の基準となるスケールを口唇の近くに配置して画像を取得することにより、各対象者間のぶれを少なくし、より正確に輝度値を解析することができる。 When capturing UV-illuminated images, a brightness reference scale is placed near the lips to capture the images, reducing blurring between subjects and enabling more accurate analysis of brightness values.

上記ステップ2では、紫外線照射画像を解析して、口唇の輝度値を評価する。輝度値の評価の方法としては、下唇の全面積に対する、輝度閾値以上となる輝度値を示す面積の割合である輝度面積割合(輝度閾値以上となる輝度値を示す面積/下唇の全面積×100)(%)を指標として用いることが好ましい。上記輝度面積割合が高いほど、口唇が荒れていると評価することができる。
例えば、複数の対象者の紫外線照射画像から、口唇の輝度面積割合を解析し、輝度面積割合値を比較することで口唇の荒れの程度を比較することができる。これにより、皮剥けの無いきれいな口唇を有する対象者間でも、荒れの程度を評価することができ、対象者に適した口唇美容法や保湿剤等の提案が可能となる。
上記輝度閾値以上となる輝度値を示す面積とは、下唇を一定区画毎に輝度値を測定し、上記輝度閾値以上の輝度値を示す区画の合計面積をいうものとする。なお、上記解析において、下唇画像の1ピクセルを1区画としてもよいし、複数ピクセル(例えば、2~100ピクセルのいずれか)を1区画としてもよい。
上記輝度値の測定は、全対象者で同じ方法で測定すればよく、紫外線照射画像から目的の部位(例えば下唇)を切り取り、画像解析ソフトを用いて各区画の輝度値を測定してよい。輝度値の解析には、画像処理ソフトImageJを用いることが好ましい。
In step 2, the ultraviolet light image is analyzed to evaluate the luminance value of the lips. A preferred method for evaluating the luminance value is to use the luminance area ratio (area showing luminance values above the luminance threshold/total area of the lower lip x 100) (%) as an index, which is the ratio of the area showing luminance values above the luminance threshold to the total area of the lower lip. The higher the luminance area ratio, the more chapped the lips can be evaluated to be.
For example, by analyzing the luminance area ratio of lips from UV-illuminated images of multiple subjects and comparing the luminance area ratio values, it is possible to compare the degree of lip chappedness. This makes it possible to evaluate the degree of chapped lips even among subjects with clean, unpeeled lips, and to propose lip beauty methods and moisturizers that are suitable for each subject.
The area showing a luminance value equal to or greater than the luminance threshold is the total area of the sections of the lower lip that show a luminance value equal to or greater than the luminance threshold when the luminance value is measured for each section of the lower lip. Note that in the above analysis, one section may be one pixel of the lower lip image, or multiple pixels (for example, 2 to 100 pixels).
The brightness values may be measured in the same manner for all subjects, by cutting out a target area (e.g., the lower lip) from the ultraviolet light image and measuring the brightness value of each section using image analysis software. ImageJ is preferably used as image processing software for analyzing brightness values.

上記ステップ2において、輝度値の評価の方法としては、輝度面積割合閾値に対する上記輝度面積割合の大きさから口唇の輝度値を評価することが好ましい。
例えば、縦軸に複数名の対象者の輝度面積割合のプロットした1変数散布図を作成し、輝度面積割合閾値と比べて高い値の対象者群と、低い値の対象者群とに分けることができる。輝度面積割合閾値を調整することで、より荒れが少ない群や、より荒れが多い群に分類することが可能となり、提案する口唇美容法や保湿剤等に応じた口唇の分類が可能となる。
In step 2, the method for evaluating the luminance value is preferably to evaluate the luminance value of the lips from the magnitude of the luminance area ratio relative to a luminance area ratio threshold.
For example, a one-variable scatter plot can be created in which the luminance area ratios of multiple subjects are plotted on the vertical axis, and the subjects can be divided into a group with higher values than the luminance area ratio threshold and a group with lower values. By adjusting the luminance area ratio threshold, it becomes possible to classify the subjects into groups with less roughness and groups with more roughness, and it becomes possible to classify the lips according to the proposed lip beauty method, moisturizer, etc.

本実施形態の輝度閾値を決定する方法は、上述の本実施形態の口唇荒れの評価方法における上記輝度閾値を決定する方法である。本実施形態の輝度面積割合閾値を決定する方法は、上述の本実施形態の口唇荒れの評価方法における上記輝度面積割合閾値を決定する方法である。輝度閾値と輝度面積割合閾値とは、それぞれ別に決定してもよいし、同時に決定してもよい。
上記輝度閾値及び/又は上記輝度面積割合閾値は、口唇に関する特性に基づき決定してよい。
The method for determining the brightness threshold value of this embodiment is the method for determining the brightness threshold value in the method for evaluating chapped lips of this embodiment described above.The method for determining the brightness area ratio threshold value of this embodiment is the method for determining the brightness area ratio threshold value in the method for evaluating chapped lips of this embodiment described above.The brightness threshold value and the brightness area ratio threshold value may be determined separately or simultaneously.
The luminance threshold and/or the luminance area ratio threshold may be determined based on characteristics related to the lips.

上記輝度閾値を低くすると、小さな輝度値を含めて輝度面積割合を算出することとなり、紫外線照射画像において比較的低い輝度値を含めて求めた輝度面積割合に基づいて対象者を分類できる。例えば、皮剥けの無いきれいな口唇において、荒れの程度がひどい場合から健康に近い場合までの広い範囲に適用可能な美容方法を提案しようとする場合、輝度閾値を低くすることで、目的の対象者を分類することができる。
一方、上記輝度閾値を高くすると、紫外線照射画像においてかなり高い輝度値のみから求めた輝度面積割合に基づいて対象者を分類できる。例えば、皮剥けの無いきれいな口唇において、荒れの程度がひどい場合に適用可能な美容方法を提案しようとする場合、輝度閾値を高くすることで、目的の対象者を分類することができる。
また、特定の範囲の輝度値を示す面積の割合が高い対象者へ提案する美容方法がある場合、2つの輝度閾値を設定して該閾値間の輝度面積割合を示す対象者のみを分類することも可能となる。
輝度閾値は、1つであってもよいし、複数設けてもよい。輝度閾値を複数設けることで、皮剥けの無い口唇の荒れ状態をより詳細に分類することができる。
If the brightness threshold is set low, the brightness area ratio will be calculated including small brightness values, and the subject can be classified based on the brightness area ratio calculated including relatively low brightness values in the ultraviolet irradiation image. For example, when proposing a beauty treatment that can be applied to a wide range of lips, from those with severe chapped lips to those with almost healthy lips, the target subject can be classified by setting the brightness threshold low.
On the other hand, if the brightness threshold is set high, subjects can be classified based on the brightness area ratio calculated from only the significantly high brightness values in the ultraviolet irradiation image. For example, when proposing a cosmetic treatment that can be applied to a clean, unpeeled lip with severe chapped lips, the target subjects can be classified by setting the brightness threshold high.
Furthermore, if there is a beauty treatment method to be proposed to a subject who has a high proportion of area showing brightness values in a specific range, it is possible to set two brightness thresholds and classify only subjects who show a brightness area proportion between the thresholds.
The brightness threshold may be one or more. By providing a plurality of brightness thresholds, the state of chapped lips without peeling can be classified in more detail.

上記輝度閾値は、目視・触診評価による「口唇が張っており、触るとカサカサしており、口唇のしっとりした感じがない状態」を基準とした分類、水分量が変わらないものの水分蒸散量が異なることを基準とした分類をより正確に識別できる観点から、60~90の範囲のいずれか一点であることが好ましく、より好ましくは70~80の範囲のいずれか一点、さらに好ましくは75である。 The brightness threshold is preferably any point in the range of 60 to 90, more preferably any point in the range of 70 to 80, and even more preferably 75, from the viewpoint of being able to more accurately distinguish between classifications based on visual and palpation evaluations of "lips that are taut, dry to the touch, and not moist," and classifications based on the fact that moisture content remains the same but the amount of moisture evaporation differs.

上記輝度面積割合閾値を低くすると、紫外線照射画像において輝度面積割合が比較的低い対象者から、高い対象者までを含む範囲の対象者を分類できる。例えば、皮剥けの無いきれいな口唇において、荒れの程度がひどい場合から健康に近い場合までの広い範囲に適用可能な美容方法を提案しようとする場合、輝度面積割合閾値を低くすることで、目的の対象者を分類することができる。
上記輝度面積割合閾値を高くすると、紫外線照射画像において輝度面積割合がかなり高い対象者を分類できる。例えば、皮剥けの無いきれいな口唇において、荒れの程度がひどい場合に適用可能な美容方法を提案しようとする場合、輝度面積割合閾値を高くすることで、目的の対象者を分類することができる。
また、輝度面積割合が特定の範囲の対象者へ提案する美容方法がある場合、2つの輝度面積割合閾値を設定して該閾値間の輝度面積割合を示す対象者のみを分類することも可能となる。
輝度面積割合閾値は、1つであってもよいし、複数設けてもよい。輝度面積割合閾値を複数設けることで、皮剥けの無い口唇の荒れ状態をより詳細に分類することができる。
By lowering the brightness area ratio threshold, it is possible to classify subjects into a range of subjects having a relatively low brightness area ratio in the ultraviolet irradiation image to subjects having a high brightness area ratio. For example, when proposing a beauty treatment that can be applied to a wide range of lips, from those with severe chapped lips to those with almost healthy lips, it is possible to classify the target subjects by lowering the brightness area ratio threshold.
By increasing the brightness area ratio threshold, it is possible to classify subjects with a significantly high brightness area ratio in the ultraviolet irradiation image. For example, when proposing a cosmetic treatment applicable to a clean, unpeeled lip with severe chapped lips, it is possible to classify the target subject by increasing the brightness area ratio threshold.
Furthermore, if there is a beauty method that is recommended to subjects whose brightness area ratio falls within a specific range, it is possible to set two brightness area ratio thresholds and classify only subjects whose brightness area ratio falls between the thresholds.
The brightness area ratio threshold may be one or more. By providing a plurality of brightness area ratio thresholds, the state of chapped lips without peeling can be classified in more detail.

上記輝度面積割合閾値は、目視・触診評価による「口唇が張っており、触るとカサカサしており、口唇のしっとりした感じがない状態」を基準とした分類、水分量が変わらないものの水分蒸散量が異なることを基準とした分類をより正確に識別できる観点から、5~20%の範囲のいずれか一点であることが好ましく、より好ましくは5~15%の範囲のいずれか一点、さらに好ましくは10%である。
また、輝度閾値が75であり、輝度面積割合閾値が5~15%の範囲のいずれか一点であることが好ましい。
The brightness area ratio threshold is preferably any one point in the range of 5 to 20%, more preferably any one point in the range of 5 to 15%, and even more preferably 10%, from the viewpoint of being able to more accurately distinguish between classifications based on a visual and palpation evaluation of "lips that are taut, dry to the touch, and not moist" and classifications based on the fact that the moisture content remains the same but the amount of moisture evaporation is different.
It is also preferable that the brightness threshold is 75 and the brightness area ratio threshold is any one point in the range of 5 to 15%.

上記輝度閾値と上記輝度面積割合閾値(%)との和は、皮剥けの無い外観がきれいな口唇における荒れ状態をより正確に分類できる観点から、65~110であることが好ましく、より好ましくは75~95、更に好ましくは80~90である。 The sum of the brightness threshold and the brightness area percentage threshold (%) is preferably 65 to 110, more preferably 75 to 95, and even more preferably 80 to 90, from the perspective of being able to more accurately classify the condition of chapped lips that have a clean, unpeeled appearance.

上記輝度閾値及び/又は上記輝度面積割合閾値を決定する際の基準としては、例えば、口唇のパラメータを用いることができる。
以下に決定の例を記載する。
As a criterion for determining the brightness threshold and/or the brightness area ratio threshold, for example, parameters of the lips can be used.
The following are examples of decisions:

本発明者らは、皮剥けの無い、外観がきれいな口唇の専門評価者による分類について検討を進めたところ、目視評価と触診評価とを組み合わせることで、外観がきれいな口唇の中でも、荒れた状態のもの(状態B)と、健常な状態のもの(状態C)との傾向があることを見出した。この傾向に分類する基準は、「口唇が張っており、触るとカサカサしており、口唇のしっとりした感じがない状態」であることを見出した。
そして、縦軸に複数名の対象者の輝度面積割合のプロットした1変数散布図と、上記基準による分類とを比較すると、状態Bは輝度面積割合が高く、状態Cは輝度面積割合が低く分布することを見出した。すなわち、口唇の張りが強くカサカサがひどいほど輝度面積割合が高い傾向にあった。
上記輝度閾値及び上記輝度面積割合閾値としては、口唇の専門評価者による上記基準を用いた状態Bと状態Cとの分類との合致率が高くなるように決定することができる。
この閾値設定により、専門評価者の目視及び触診評価を行うことなく、画像のみから各状態に適した口唇美容法や保湿剤等の提案が可能となる。
The present inventors have investigated the classification of lips with a clean appearance by expert evaluators, and have found that by combining visual evaluation and palpation evaluation, even among lips with a clean appearance, there is a tendency for lips to be divided into those in a chapped state (state B) and those in a healthy state (state C).The inventors have found that the criteria for this classification are "lips that are taut, dry to the touch, and do not feel moist."
Then, by comparing a one-variable scatter diagram in which the luminance area ratio of multiple subjects is plotted on the vertical axis with the classification based on the above criteria, it was found that the luminance area ratio was high in condition B and low in condition C. In other words, the luminance area ratio tended to be higher the more taut and dry the lips were.
The brightness threshold and the brightness area ratio threshold can be determined so as to increase the coincidence rate with the classification of condition B and condition C by a specialist lip evaluator using the above criteria.
By setting this threshold, it becomes possible to suggest lip cosmetic methods, moisturizers, etc. that are suitable for each condition based on the image alone, without the need for visual or tactile evaluation by a specialist evaluator.

本発明者らは、皮剥けの無い、外観がきれいな口唇の特性についてさらなる検討を進めたところ、輝度面積割合が高い群と輝度面積割合が低い群とで水分量は変わらないものの、輝度面積割合が高い群で水分蒸散量(TEWL)が高く、輝度面積割合が低い群で水分蒸散量(TEWL)が低い傾向があることを見出した。そして、縦軸に輝度面積割合、横軸に水分蒸散量をプロットした散布図において、正の相関がみられることを見出した。
上記輝度閾値及び上記輝度面積割合閾値としては、水分蒸散量の値を基準に設定することができる。例えば、複数名(例えば100名)の皮剥けの無い外観がきれいな口唇の水分蒸散量を測定し、水分蒸散量が高い群と低い群との間で有意差が付く水分蒸散量の基準を設定し、該基準に相当する輝度値又は輝度面積割合を閾値として設定してよい。
この閾値設定により、水分量、水分蒸散量を測定することなく、画像のみから、水分量が変わらないものの水分蒸散量が高い対象者を分類でき、適当な口唇美容法や保湿剤等の提案が可能となる。
なお、口唇の水分量及び水分蒸散量は、後述の実施例に記載の方法で測定することができる。
The inventors further investigated the characteristics of lips that are free of peeling and have a clean appearance, and found that although the moisture content is the same between the group with a high luminance area ratio and the group with a low luminance area ratio, the group with a high luminance area ratio tends to have a high TEWL rate, while the group with a low luminance area ratio tends to have a low TEWL rate. They also found that a positive correlation was observed in a scatter diagram in which the luminance area ratio was plotted on the vertical axis and the TEWL rate on the horizontal axis.
The brightness threshold and the brightness area ratio threshold can be set based on the value of the amount of water evaporation. For example, the amount of water evaporation of lips with a clean appearance and no peeling of a plurality of people (e.g., 100 people) can be measured, a standard of the amount of water evaporation that shows a significant difference between a group with high water evaporation and a group with low water evaporation can be set, and a brightness value or a brightness area ratio corresponding to the standard can be set as the threshold.
By setting this threshold, it is possible to classify subjects who have the same moisture content but high moisture evaporation rates from images alone, without measuring moisture content or moisture evaporation rates, and to suggest appropriate lip beauty methods, moisturizers, etc.
The moisture content and evaporation rate of moisture on the lips can be measured by the method described in the Examples below.

本発明者らは、皮剥けの無い、外観がきれいな口唇の特性についてさらなる検討を進めたところ、輝度面積割合が高い群で弾性(Δf)が高く、輝度面積割合が低い群で弾性(Δf)が低い傾向があることを見出した。
上記輝度閾値及び上記輝度面積割合閾値としては、弾性(Δf)の値を基準に設定することができる。例えば、複数名(例えば100名)の皮剥けの無い外観がきれいな口唇の弾性(Δf)を測定し、弾性(Δf)が高い群と低い群との間で有意差が付く弾性(Δf)の基準を設定し、該基準に相当する輝度値又は輝度面積割合を閾値として設定してよい。また、弾性(Δf)が高い群と低い群との間で、Δf値の差が20以上(好ましくは30以上)となるように基準を設定し、該基準に相当する輝度値又は輝度面積割合を閾値として設定してよい。
この閾値設定により、弾性(Δf)を測定することなく、画像のみから、弾性(Δf)が高い対象者を分類でき、適当な口唇美容法や保湿剤等の提案が可能となる。
なお、弾性(Δf)は、後述の実施例に記載の方法で測定することができる。
The inventors further investigated the characteristics of lips that are free of peeling and have a clean appearance, and found that the group with a high luminance area ratio tends to have high elasticity (Δf), and the group with a low luminance area ratio tends to have low elasticity (Δf).
The brightness threshold and the brightness area ratio threshold can be set based on the value of elasticity (Δf). For example, the elasticity (Δf) of lips with a clean appearance and no peeling of multiple people (e.g., 100 people) can be measured, a standard of elasticity (Δf) that shows a significant difference between a group with high elasticity (Δf) and a group with low elasticity (Δf) can be set, and a brightness value or brightness area ratio corresponding to the standard can be set as the threshold. Alternatively, a standard can be set so that the difference in Δf value between a group with high elasticity (Δf) and a group with low elasticity (Δf) is 20 or more (preferably 30 or more), and a brightness value or brightness area ratio corresponding to the standard can be set as the threshold.
By setting this threshold, subjects with high elasticity (Δf) can be classified from images alone without measuring elasticity (Δf), making it possible to suggest appropriate lip beauty methods, moisturizers, etc.
The elasticity (Δf) can be measured by the method described in the examples below.

本実施形態の口唇荒れの評価方法、輝度閾値を決定する方法、輝度面積割合閾値を決定する方法は、例えば、皮剥けの無い、外観がきれいな口唇を分類して、対象者に適した美容方法や美容薬を提案する際等に使用することができる。 The lip chappedness evaluation method, brightness threshold determination method, and brightness area ratio threshold determination method of this embodiment can be used, for example, to classify lips that are free of peeling and have a clean appearance, and to suggest beauty treatments and cosmetic products that are suitable for the subject.

上述の口唇荒れの評価方法は、例えば、事前に複数名(例えば100名等)の紫外線照射画像から、輝度閾値及び輝度面積割合閾値を決定し、その後、上述の本実施形態の口唇荒れの評価方法により対象者の口唇荒れを評価してよい。対象者の測定値および撮影画像をデータ・ベースとしてインプットし、新たな対象者を測定するごとに測定値および撮影画像をデータ・ベースに追加保管してもよい。閾値を事前に決定することにより、可視光照射画像及び紫外線照射画像があれば、遠隔地の対象者であっても口唇を評価可能となり、測定値をデータ処理するシステムを作成し、データ・ベースに測定値と撮影画像を情報保管し、口唇分類の精度を向上させることができる。遠隔地の対象者の測定値から、上記データ・ベース、上記システムを用いて口唇荒れの分類を評価し、予め決定された口唇荒れの分類と口唇化粧料及び/又は外用剤との関連データも用いて、遠隔地の上記対象者に提案できる推奨口唇化粧料及び/又は外用剤を表示し、美容方法や美容薬の推奨を含めたカウンセリング提案することが可能となる。
また、口唇荒れの傾向は、地域や時期ごとに異なることがある。例えば、地域や時期ごとに閾値を変えることで、地域や時期に適した美容方法や美容薬の提案が可能となる。
また、本実施形態の口唇荒れの評価方法では、1つの可視光照射画像及び1つの紫外線照射画像から、輝度閾値と輝度面積割合閾値との1組の組み合わせを用いて1種の評価を行ってもよいし、輝度閾値と輝度面積合閾値との複数の組み合わせを用いて複数種の評価(例えば、水分蒸散量と弾性の評価)を同時に行ってもよい。
また、推奨する口唇の化粧料及び外用剤としては、例えば、目視・触診評価において皮剥けが見られ、表面が硬く、水分量も少ない群の対象者には、水分を補う製剤、又は薬剤を付与することが好ましく、具体的には、水性成分の付与や保水性物質、口唇浸透性の高い物質を付与することが好ましく、また、例えば、目視・触診評価において少し乾燥感を感じ、水分蒸散量が高い群の対象者には、水分蒸散量を抑制するために、水分閉塞性の高い製剤、または薬剤を付与することが好ましく、具体的には、水を透過させにくい油剤や皮膜、水を吸収しにくい物質によって構成するものが好ましいが、これらは特に限定するものではない。
The above-described method for evaluating chapped lips may involve, for example, determining a brightness threshold and a brightness area ratio threshold in advance from UV-irradiated images of multiple subjects (e.g., 100 subjects), and then evaluating the subject's chapped lips using the method for evaluating chapped lips of this embodiment. The subject's measurements and photographed images may be input into a database, and the measurements and photographed images may be added to the database each time a new subject is measured. By determining the thresholds in advance, it becomes possible to evaluate the lips of even remotely located subjects using only images irradiated with visible light and UV light. A system for processing measurements may be created, and the measurements and photographed images may be stored in a database, improving the accuracy of lip classification. The measurement values of a remotely located subject may be evaluated using the database and system, and the association data between the previously determined chapped lip classification and lip cosmetics and/or topical preparations may also be used to display recommended lip cosmetics and/or topical preparations that can be recommended to the remotely located subject, enabling counseling suggestions, including recommendations for beauty treatments and beauty products.
Furthermore, lip chappedness trends can vary by region and time of year. For example, by changing the threshold for each region and time of year, it becomes possible to suggest beauty methods and beauty products that are appropriate for each region and time of year.
Furthermore, in the method for evaluating chapped lips of this embodiment, one type of evaluation may be performed using one combination of a brightness threshold and a brightness area ratio threshold from one visible light irradiation image and one ultraviolet light irradiation image, or multiple types of evaluation (e.g., evaluation of water evaporation rate and elasticity) may be performed simultaneously using multiple combinations of brightness thresholds and brightness area sum thresholds.
Furthermore, as for the recommended lip cosmetics and topical preparations, for example, for subjects in the group in which peeling is observed in visual and palpable evaluation, the surface is hard, and the moisture content is low, it is preferable to apply a preparation or drug that replenishes moisture; specifically, it is preferable to apply an aqueous component, a water-retaining substance, or a substance that has high lip permeability; and for example, for subjects in the group in which a slight dry feeling is felt in visual and palpable evaluation and the amount of moisture evaporation is high, it is preferable to apply a preparation or drug that has high moisture occlusion properties in order to suppress the amount of moisture evaporation; specifically, it is preferable to apply a preparation composed of an oil or film that is difficult for water to pass through, or a substance that does not easily absorb water, although these are not particularly limited.

本実施形態の口唇のカウンセリング方法は、上述の本実施形態の口唇荒れの評価方法を含む。例えば、口唇荒れを評価した後に、口唇荒れの評価結果に基づいて口唇のカウンセリング方法を提案してよい。
上記カウンセリング方法としては、口唇化粧料及び外用剤等の提案、対象者の現在の口唇状態の説明、口唇状態の改善のアドバイス等が挙げられる。上記カウンセリングは、対象者と同じ場所で行ってもよいし、離れた場所から行ってもよい。
The lip counseling method of this embodiment includes the above-described lip chapped evaluation method of this embodiment. For example, after evaluating lip chappedness, a lip counseling method may be proposed based on the evaluation result of lip chappedness.
The above-mentioned counseling method includes suggesting lip cosmetics and topical preparations, etc., explaining the subject's current lip condition, giving advice on improving the lip condition, etc. The above-mentioned counseling may be carried out in the same place as the subject or from a remote location.

以下に、実施例に基づいて本発明をより詳細に説明するが、本発明はこれらの実施例により限定されるものではない。 The present invention will be described in more detail below based on examples, but the present invention is not limited to these examples.

(実施例1)
3名の対象者A、B、Cについて、以下の方法で口唇の荒れを評価した。
VISIA-CR(Canfield Scientific社製)を用いて、各対象者の可視光照射画像、紫外線照射画像を得た。画像は、LIGHTING MODESをStandard1又はUV Fluorescenceに設定して、Resolutionを約2000万画素として取得した。
得られた可視光照射画像から皮剥けの有無を判定した。なお、「皮剥け有り」とは、口唇表面上の皮が一部でも剥けている状態のことをいう。図2中の丸で囲った箇所は、皮剥け有りの箇所である。対象者Aに皮剥けが見られ、対象者B及びCは皮剥けが無かった(図1)。図2は、皮剥け有りの対象者Aの口唇の拡大図である。
次に、皮剥け無しの2名の対象者B、Cについて、紫外線照射画像を用いて以下の方法で輝度値を評価した。紫外線照射画像から下唇部分を切り取り、画像解析ソフト「ImageJ」を用いて、各ピクセルの輝度を測定した(図1、3)。輝度は、画像の明るさを256階調のグレースケール画像に変換して求めた。具体的には、ImageJのColor Threshold機能を用いて、解析した。
そして、輝度閾値を75として、輝度値を二値化した(図3)。そして、以下の式を用いて各対象者の輝度面積割合を算出した。
輝度面積割合(%)=75以上となる輝度値を示す面積/下唇の全面積×100
そして、輝度面積割合が高い(35.04%)対象者B(図4)と、輝度面積割合が低い(0.09%)対象者C(図5)とに分類した。
Example 1
The three subjects, A, B, and C, were evaluated for lip chappedness using the following method.
Visible light and ultraviolet light images of each subject were obtained using a VISIA-CR (manufactured by Canfield Scientific). The images were acquired with the lighting mode set to Standard 1 or UV Fluorescence and a resolution of approximately 20 million pixels.
The presence or absence of peeling was determined from the obtained visible light irradiation image. "Peeled" refers to a state in which even a portion of the skin on the surface of the lips has peeled. The circled areas in Figure 2 are areas where peeling has occurred. Peeling was observed in subject A, while subjects B and C did not have peeling (Figure 1). Figure 2 is an enlarged view of the lips of subject A with peeling.
Next, for two subjects B and C without peeling, brightness values were evaluated using UV-irradiated images as follows. The lower lip portion was cut out from the UV-irradiated image, and the brightness of each pixel was measured using the image analysis software "ImageJ" (Figures 1 and 3). Brightness was determined by converting the brightness of the image into a 256-level grayscale image. Specifically, analysis was performed using the Color Threshold function of ImageJ.
The brightness values were then binarized using a brightness threshold of 75 (Figure 3). The brightness area ratio for each subject was then calculated using the following formula:
Brightness area ratio (%) = area showing a brightness value of 75 or more / total area of lower lip × 100
The subjects were then classified into Subject B (Fig. 4) with a high luminance area ratio (35.04%) and Subject C (Fig. 5) with a low luminance area ratio (0.09%).

分類後の3名について、専門評価者による口唇の目視評価を行ったところ、対象者Aのみに皮剥けがみられることを確認した。また、専門評価者が目視評価と触診評価とを行ったところ、対象者Bは口唇が張っており、触るとカサカサしており、口唇のしっとりした感じがない状態であり、対象者Cは健常であった。上記評価により、皮剥けの無い外観がきれいな口唇を分類できた。
また、後述の方法で、対象者B及びCの水分蒸散量(TEWL)及び弾性(Δf)を測定したところ、いずれの値も対象者Bの方が高かった。
After classification, a professional evaluator visually evaluated the lips of the three subjects and confirmed that peeling was only observed in subject A. Furthermore, the professional evaluator conducted visual and palpation evaluations and found that subject B's lips were taut, dry to the touch, and not moist, while subject C's lips were healthy. Based on the above evaluations, lips with a clean appearance and no peeling could be classified.
Furthermore, when the transpiration water loss (TEWL) and elasticity (Δf) of subjects B and C were measured using the methods described below, subject B had higher values in both cases.

(実施例2)
20~50代の57名(男性25名・女性32名)の対象者に対し、異なる時期に計4回の口唇の荒れを評価した。
実施例1と同様の方法で、各対象者の可視光照射画像、紫外線照射画像を取得し、可視光照射画像から皮剥けの有無を判定した。
可視光照射画像において、皮剥け無しであった対象者のべ141名について、実施例1と同様にして、口唇の輝度値を評価した。
なお、輝度閾値は、55、60、70、75、80、90に設定し、また、輝度面積割合閾値は、2.5%、5%、7.5%、10%、12.5%、15%、17.5%、20%に設定して、それぞれ解析を行った。そして、各閾値で解析した後に、輝度面積割合閾値以上であった群と、輝度面積割合閾値未満であった群とに分類した
また、皮剥けの無かった全対象者に対し、専門評価者による目視及び触診評価を行い、「口唇が張っており、触るとカサカサしており、口唇のしっとりした感じがない状態」(状態B)である群と、健常な状態(状態C)である群とに分類した。
そして、皮剥けの無かった全対象者数に対する、輝度面積割合閾値以上であり且つ専門評価者の評価が状態Bであった対象者数と輝度面積割合閾値未満であり且つ専門評価者の評価が状態Cであった対象者数との合計の割合である合致率を、以下の式から算出した。
合致率(%)={(輝度面積割合閾値以上であり且つ専門評価者の評価が状態Bである対象者数)+(輝度面積割合閾値未満であり且つ専門評価者の評価が状態Cである対象者)}/皮剥けの無かった全対象者数×100
結果を図6に示す。なお、図中の「-」は未評価を表す。
輝度閾値が75であり、輝度面積割合閾値が10%のときに、専門評価者による状態B-C分類との合致率が最も高かった。特に、輝度閾値と輝度面積割合閾値との和が、82.5~90では、合致率が83%以上で極めて高かった。
Example 2
The lip chapping of 57 subjects (25 men and 32 women) in their 20s to 50s was evaluated four times at different times.
In the same manner as in Example 1, images of each subject exposed to visible light and ultraviolet light were obtained, and the presence or absence of peeling was determined from the images exposed to visible light.
The luminance values of the lips of a total of 141 subjects who did not have peeling in the visible light irradiation images were evaluated in the same manner as in Example 1.
The brightness threshold was set to 55, 60, 70, 75, 80, and 90, and the brightness area ratio threshold was set to 2.5%, 5%, 7.5%, 10%, 12.5%, 15%, 17.5%, and 20%, and analysis was performed for each. After analysis at each threshold, subjects were classified into a group whose brightness area ratio was equal to or greater than the brightness area ratio threshold and a group whose brightness area ratio was less than the brightness area ratio threshold. Furthermore, all subjects who did not experience peeling underwent visual and tactile evaluation by a specialist evaluator, and were classified into a group whose "lips were taut, dry to the touch, and not moist" (condition B) and a group whose lips were in a healthy condition (condition C).
The agreement rate, which is the ratio of the total number of subjects who had peeling above the brightness area ratio threshold and who were evaluated by the expert evaluator as being in condition B to the total number of subjects who had peeling below the brightness area ratio threshold and who were evaluated by the expert evaluator as being in condition C, was calculated using the following formula.
Matching rate (%) = {(Number of subjects whose brightness area ratio is equal to or greater than the threshold and whose expert evaluator's evaluation is condition B) + (Number of subjects whose brightness area ratio is less than the threshold and whose expert evaluator's evaluation is condition C)} / Total number of subjects without peeling × 100
The results are shown in Figure 6. In the figure, "-" indicates that the evaluation was not performed.
The highest agreement rate with the expert evaluator's condition B-C classification was achieved when the luminance threshold was 75 and the luminance area ratio threshold was 10%. In particular, when the sum of the luminance threshold and the luminance area ratio threshold was 82.5 to 90, the agreement rate was extremely high at 83% or more.

(実施例3)
輝度閾値75、輝度面積割合閾値10%に設定したこと以外は、実施例2と同様にして対象者を分類した。そして、皮剥け有り(群A)、皮剥け無し且つ輝度面積割合閾値10%以上(群B)、皮剥け無し且つ輝度面積割合10%未満(群C)に分類した。
また、後述の方法で、全対象者の目視評価、触診評価、水分量、水分蒸散量(TEWL)及び弾性(Δf)を測定した。結果を図7に示す。
群Bは、群Cと水分量の平均は変わらないものの、水分蒸散量の平均は有意に高かった。弾性(Δf)はBとCの有意差は確認できなかったものの、群A>群B>群Cの傾向がみられた。
Example 3
Except for setting the brightness threshold to 75 and the brightness area ratio threshold to 10%, subjects were classified in the same manner as in Example 2. They were then classified into those with peeling (Group A), those without peeling and a brightness area ratio threshold of 10% or more (Group B), and those without peeling and a brightness area ratio of less than 10% (Group C).
In addition, visual evaluation, palpation evaluation, moisture content, transpiration water loss (TEWL), and elasticity (Δf) were measured for all subjects using the methods described below. The results are shown in Figure 7.
Although the average moisture content of Group B was the same as that of Group C, the average water loss was significantly higher. Although no significant difference in elasticity (Δf) was confirmed between B and C, a tendency of Group A > Group B > Group C was observed.

(実施例4)
実施例2の可視光照射画像で皮剥けが無かった対象者に対して、実施例3と同様の方法で、水分量、水分蒸散量を測定した。そして、水分量は変化がなく、水分蒸散量に有意差が付くように輝度閾値及び輝度面積割合閾値を設定したところ、輝度閾値は75、輝度面積割合閾値は10%であった。
Example 4
For subjects who did not have peeling in the visible light irradiation image of Example 2, the moisture content and moisture evaporation rate were measured using the same method as in Example 3. Then, the brightness threshold and brightness area ratio threshold were set so that there was no change in moisture content and a significant difference in moisture evaporation rate, and the brightness threshold was 75 and the brightness area ratio threshold was 10%.

(実施例5)
実施例2の可視光照射画像で皮剥けが無かった対象者に対して、実施例3と同様の方法で、Δfを測定した。そして、輝度面積割合閾値以上の群と、輝度面積割合閾値未満の群とでΔfが有意差が付くように、輝度閾値及び輝度面積割合閾値を設定したところ、輝度閾値は80、輝度面積割合閾値は15%であった。
Example 5
For subjects who did not have peeling in the visible light irradiation image of Example 2, Δf was measured in the same manner as in Example 3. Then, the brightness threshold and brightness area ratio threshold were set so that there would be a significant difference in Δf between the group with brightness area ratio equal to or greater than the threshold and the group with brightness area ratio less than the threshold, and the brightness threshold was found to be 80 and 15%.

(実施例6)
6名の対象者に対し、12日間連続して、口唇荒れを評価した。
口唇荒れの評価は、輝度閾値75、輝度面積割合閾値10%に設定したこと以外は、実施例2と同様にして対象者を分類した。そして、皮剥け有り(群A)、皮剥け無し且つ輝度面積割合閾値10%以上(群B)、皮剥け無し且つ輝度面積割合10%未満(群C)に分類した。
結果を図8に示す。なお、図中の「-」は未評価を表す。
Example 6
Six subjects were evaluated for chapped lips for 12 consecutive days.
For the evaluation of chapped lips, subjects were classified in the same manner as in Example 2, except that the brightness threshold was set at 75 and the brightness area percentage threshold was set at 10%. Subjects were then classified into those with peeling (Group A), those without peeling and a brightness area percentage threshold of 10% or more (Group B), and those without peeling and a brightness area percentage of less than 10% (Group C).
The results are shown in Figure 8. In the figure, "-" indicates that the evaluation was not performed.

[評価]
各実施例における評価は、下記の方法で行った。
[evaluation]
The evaluations in each example were carried out by the following methods.

(1.目視評価)
専門評価者3名が予め基準となる口唇状態を共有した後、対象者の口唇を目視した際の印象に基づき、以下の基準で目視評価した。スコアは、3名の専門評価者が協議の上、決定した。
なお、目視評価では見逃し等があるため、可視光照射画像から口唇の皮剥けを評価する方法では「皮剥け有り」であっても、目視評価で下記ランク4以下となる場合がある。そのため、可視光照射画像において皮剥け有りであっても、目視評価値がランク5以下となっている(図7)。
-基準-
1:乾燥が認められず潤いが感じられ、荒れが認められない
2:乾燥が認められず、潤いが少し感じられ、荒れが認められない
3:乾燥が認められず、荒れが認められない
4:わずかに乾燥が認められるが、荒れが認められない
5:わずかに皮剥けが見られ、乾燥による荒れが認められる
6:皮剥けが見られ、より乾燥が強く、荒れが認められる
7:明確な皮剥けが見られ、さらに乾燥が強く荒れが認められる
(1. Visual Evaluation)
After the three expert evaluators shared a baseline lip condition in advance, they visually evaluated the subject's lips based on their impression when visually inspecting them, using the following criteria. The scores were determined through discussion between the three expert evaluators.
It should be noted that visual evaluation can miss some marks, so even if the method for evaluating lip peeling from an image irradiated with visible light shows "peeling present," the visual evaluation may result in a rank of 4 or lower. Therefore, even if peeling is present in the image irradiated with visible light, the visual evaluation value is ranked 5 or lower (FIG. 7).
-standard-
1: No dryness is observed, moisturized feeling, no roughness is observed 2: No dryness is observed, slight moisturized feeling, no roughness is observed 3: No dryness is observed, no roughness is observed 4: Slight dryness is observed, but no roughness is observed 5: Slight peeling is observed, and roughness due to dryness is observed 6: Peeling is observed, and more severe dryness and roughness are observed 7: Clear peeling is observed, and even more severe dryness and roughness are observed

(2.触診評価)
専門評価者3名が予め基準となる口唇表面のなめらかさ等を共有した後、対象者の口唇表面に触れたときの印象に基づき、以下の基準で口唇のなめらかさ等を触診評価した。スコアは、3名の専門評価者が協議の上、決定した。
-基準-
1:潤い感のあるもっちりとした喰いつきがありつつ、かさつきがなくなめらかな状態
2:潤い感があり、しっとりとするが、喰いつきはなく、かさつきがなく滑らかな状態
3:乾燥がなく、かさつきがなくなめらかな状態
4:少し乾燥を感じるが、かさつきはなくなめらかな状態
5:少し乾燥を感じ、カサカサとしたかさつきを感じる状態
6:乾燥を感じ、ガサガサとしたかさつきを感じる状態
7:強い乾燥があり、ガサガサ・ゴワゴワとした強いかさつきを感じる状態
(2. Palpation Evaluation)
After three expert evaluators shared the standard lip surface smoothness in advance, they evaluated the smoothness of the lips by palpation based on the impression they got when touching the lip surface of the subject, using the following criteria. The scores were determined after consultation between the three expert evaluators.
-standard-
1: Moisture-rich, chewy texture, but not dry and smooth 2: Moisture-rich, moist texture, but not dry and smooth 3: No dryness, not dry and smooth 4: Slight dryness, but not dry and smooth 5: Slight dryness, with a rough, flaky texture 6: Dryness, with a rough, flaky texture 7: Very dryness, with a rough, flaky texture

(3.水分量)
Skin Moisture Sensor MY-808S(Scalar corporation社製)を用いて、下唇中央部の水分量を測定した。測定時の条件は、温度22±2℃、湿度50%RHとした。
5回測定し、最大値と最小値を除いた3回の測定値の平均値を採用した。
(3. Moisture content)
The moisture content of the central part of the lower lip was measured using a Skin Moisture Sensor MY-808S (manufactured by Scalar Corporation) under the conditions of a temperature of 22±2°C and a humidity of 50% RH.
The measurement was carried out five times, and the average value of three measurements excluding the maximum and minimum values was used.

(4.水分蒸散量)
VAPOMETER(Delfin社製)を用いて、下唇中央部の水分蒸散量を測定した。測定条件としては、STDモード、爪用プローブを使用し、温度22±2℃、湿度50%RHの条件で行った。
5回測定し、最大値と最小値を除いた3回の測定値の平均値を採用した。
(4. Water Evaporation Amount)
The amount of water loss from the center of the lower lip was measured using a VAPOMETER (Delfin) in STD mode with a nail probe at a temperature of 22±2°C and a humidity of 50% RH.
The measurement was carried out five times, and the average value of three measurements excluding the maximum and minimum values was used.

(5.弾性評価)
VENUSTRON(AXIOM社製)を用いて、下唇中央の弾性を測定した。2mm/sで2mm侵入させたときの周波数変化(Δf)を測定した。
10回測定し、標準偏差が最も小さくなるように5回分の測定値を選択し、その平均値を採用した。
(5. Elasticity Evaluation)
The elasticity of the center of the lower lip was measured using a VENUSTRON (manufactured by AXIOM). The frequency change (Δf) when the device was penetrated 2 mm at 2 mm/s was measured.
The measurement was carried out 10 times, and the five measured values were selected so as to minimize the standard deviation, and the average value was adopted.

Claims (7)

可視光照射画像から口唇の皮剥けの有無を評価するステップ1と、
前記ステップ1において皮剥けが無かった被験者の下唇の紫外線照射画像から口唇の輝度値を評価するステップ2と、
を有し、
前記ステップ2において、前記紫外線照射画像から輝度値を評価し、前記下唇の全面積に対する輝度閾値以上となる輝度値を示す面積の割合である輝度面積割合を用いて口唇の輝度値を評価することを特徴とする口唇荒れの評価方法。
Step 1: Evaluating the presence or absence of lip peeling from the visible light irradiation image;
Step 2: Evaluating the luminance value of the lips from the ultraviolet irradiation image of the lower lip of the subject who did not have peeling in Step 1 ;
and
In step 2 , a method for evaluating chapped lips is characterized in that the brightness value is evaluated from the ultraviolet irradiation image, and the brightness value of the lips is evaluated using a brightness area ratio, which is the ratio of the area showing a brightness value equal to or greater than a brightness threshold to the total area of the lower lip.
前記紫外線照射画像が365nmを含む紫外線を照射して取得した画像である、請求項1に記載の口唇荒れの評価方法。 The method for evaluating chapped lips according to claim 1, wherein the ultraviolet irradiation image is an image acquired by irradiating the skin with ultraviolet light containing 365 nm light. 前記ステップ2において、輝度面積割合閾値に対する前記輝度面積割合の大きさから口唇の輝度値を評価する、請求項1又は2に記載の口唇荒れの評価方法。 A method for evaluating chapped lips according to claim 1 or 2, wherein in step 2, the lip luminance value is evaluated based on the magnitude of the luminance area ratio relative to a luminance area ratio threshold. 前記輝度閾値が70~80の範囲のいずれか1点である、請求項1~3のいずれか一項に記載の口唇荒れの評価方法。 The method for evaluating chapped lips according to any one of claims 1 to 3, wherein the brightness threshold is any one point in the range of 70 to 80. 前記輝度閾値が75であり、前記輝度面積割合閾値が5~15%の範囲のいずれか1点である、請求項3、又は請求項3を引用する請求項4に記載の口唇荒れの評価方法。 The method for evaluating chapped lips according to claim 3 or claim 4 that cites claim 3, wherein the brightness threshold is 75 and the brightness area ratio threshold is any one point in a range of 5 to 15%. 請求項1~5のいずれか一項に記載の口唇荒れの評価方法の輝度閾値を決定する方法であって、以下の(i)~(iii)のいずれかの方法。
(i)複数名の皮剥けの無い外観がきれいな口唇の水分蒸散量を測定し、水分蒸散量が高い群と低い群との間で有意差が付く水分蒸散量の基準を設定し、該基準に相当する輝度値を閾値とする。ここで、水分蒸散量は、VAPOMETER(登録商標)を用いて、STDモード、爪用プローブを使用し、温度22±2℃、湿度50%RHの条件で、下唇中央部を測定した値とする。
(ii)複数名の皮剥けの無い外観がきれいな口唇の弾性(Δf)を測定し、弾性(Δf)が高い群と低い群との間で有意差が付く弾性(Δf)の基準を設定し、該基準に相当する輝度値を閾値とする。ここで、弾性(Δf)は、VENUSTRON(商標)(AXIOM(商標)社製)を用いて、下唇中央の、2mm/sで2mm侵入させたときの周波数変化(Δf)を測定した値とする。
(iii)複数名の皮剥けの無い外観がきれいな口唇の弾性(Δf)を測定し、弾性(Δf)が高い群と低い群との間のΔf値の差が20以上となるように基準を設定し、該基準に相当する輝度値を閾値とする。ここで、弾性(Δf)は、VENUSTRON(商標)(AXIOM(商標)社製)を用いて、下唇中央の、2mm/sで2mm侵入させたときの周波数変化(Δf)を測定した値とする。
A method for determining a brightness threshold for the method for evaluating chapped lips according to any one of claims 1 to 5, comprising any one of the following methods (i) to (iii):
(i) The amount of water evaporation from lips with a clean appearance and no peeling was measured on multiple subjects, a standard for the amount of water evaporation that shows a significant difference between a group with high water evaporation and a group with low water evaporation was set, and the brightness value corresponding to this standard was set as the threshold value. Here, the amount of water evaporation was measured at the center of the lower lip using a VAPOMETER (registered trademark) in STD mode with a nail probe under conditions of a temperature of 22±2°C and a humidity of 50% RH.
(ii) The elasticity (Δf) of lips with a clean appearance and no peeling was measured on multiple subjects, and a standard for elasticity (Δf) that resulted in a significant difference between a group with high elasticity (Δf) and a group with low elasticity (Δf) was set, and the brightness value corresponding to this standard was used as the threshold value. Here, the elasticity (Δf) was defined as the value measured for the change in frequency (Δf) when a VENUSTRON (trademark ) probe (manufactured by AXIOM) was inserted 2 mm into the center of the lower lip at a speed of 2 mm/s.
(iii) The elasticity (Δf) of lips with a clean appearance and no peeling was measured for multiple subjects, and a standard was set so that the difference in Δf values between a group with high elasticity (Δf) and a group with low elasticity (Δf) was 20 or more, and the brightness value corresponding to this standard was used as the threshold value. Here, the elasticity (Δf) was defined as the value measured for the change in frequency (Δf) when a VENUSTRON (trademark) ( manufactured by AXIOM) was inserted 2 mm into the center of the lower lip at 2 mm/s.
請求項1~5のいずれか一項に記載の口唇荒れの評価方法の輝度面積割合閾値を決定する方法であって、以下の(i)~(iii)のいずれかの方法。
(i)複数名の皮剥けの無い外観がきれいな口唇の水分蒸散量を測定し、水分蒸散量が高い群と低い群との間で有意差が付く水分蒸散量の基準を設定し、該基準に相当する輝度面積割合を閾値とする。ここで、水分蒸散量は、VAPOMETER(登録商標)を用いて、STDモード、爪用プローブを使用し、温度22±2℃、湿度50%RHの条件で、下唇中央部を測定した値とする。
(ii)複数名の皮剥けの無い外観がきれいな口唇の弾性(Δf)を測定し、弾性(Δf)が高い群と低い群との間で有意差が付く弾性(Δf)の基準を設定し、該基準に相当する輝度面積割合を閾値とする。ここで、弾性(Δf)は、VENUSTRON(商標)(AXIOM(商標)社製)を用いて、下唇中央の、2mm/sで2mm侵入させたときの周波数変化(Δf)を測定した値とする。
(iii)複数名の皮剥けの無い外観がきれいな口唇の弾性(Δf)を測定し、弾性(Δf)が高い群と低い群との間のΔf値の差が20以上となるように基準を設定し、該基準に相当する輝度面積割合を閾値とする。ここで、弾性(Δf)は、VENUSTRON(商標)(AXIOM(商標)社製)を用いて、下唇中央の、2mm/sで2mm侵入させたときの周波数変化(Δf)を測定した値とする。
A method for determining a luminance area ratio threshold for the lip chapped evaluation method according to any one of claims 1 to 5, comprising any one of the following methods (i) to (iii):
(i) The amount of water evaporation from lips with a clean appearance and no peeling was measured on multiple subjects, a standard for the amount of water evaporation that resulted in a significant difference between a group with high water evaporation and a group with low water evaporation was set, and the brightness area ratio corresponding to this standard was set as the threshold value. Here, the amount of water evaporation was measured at the center of the lower lip using a VAPOMETER (registered trademark) in STD mode with a nail probe under conditions of a temperature of 22±2°C and a humidity of 50% RH.
(ii) The elasticity (Δf) of lips with a clean appearance and no peeling was measured on multiple subjects, and a standard for elasticity (Δf) that resulted in a significant difference between a group with high elasticity (Δf) and a group with low elasticity (Δf) was set, and the brightness area ratio corresponding to this standard was used as the threshold value. Here, the elasticity (Δf) was defined as the value measured for the frequency change (Δf) when a VENUSTRON (trademark ) probe (manufactured by AXIOM) was inserted 2 mm into the center of the lower lip at a speed of 2 mm/s.
(iii) The elasticity (Δf) of lips with a clean appearance and no peeling was measured for multiple subjects, and a standard was set so that the difference in Δf values between a group with high elasticity (Δf) and a group with low elasticity (Δf) was 20 or more, and the brightness area ratio corresponding to this standard was used as the threshold. Here, the elasticity (Δf) was defined as the value measured for the change in frequency (Δf) when a VENUSTRON (trademark) ( manufactured by AXIOM) was inserted 2 mm into the center of the lower lip at 2 mm/s.
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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005230301A (en) 2004-02-20 2005-09-02 Kose Corp Evaluation method for chap of lip
JP2008281496A (en) 2007-05-11 2008-11-20 Kose Corp Method of evaluating lip roughness
JP2009298726A (en) 2008-06-12 2009-12-24 Naris Cosmetics Co Ltd Lip cosmetic, candy and chewing gum
US20100309300A1 (en) 2008-09-13 2010-12-09 Rajeshwar Chhibber Method and System for Analyzing Physical Conditions Using Digital Images
JP2017164458A (en) 2016-03-15 2017-09-21 株式会社コーセー Lip dull evaluation method and lip dull evaluation model
CN111840141A (en) 2020-08-13 2020-10-30 广州珈纳生物科技有限公司 A natural antioxidant composition for lips containing astaxanthin

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005230301A (en) 2004-02-20 2005-09-02 Kose Corp Evaluation method for chap of lip
JP2008281496A (en) 2007-05-11 2008-11-20 Kose Corp Method of evaluating lip roughness
JP2009298726A (en) 2008-06-12 2009-12-24 Naris Cosmetics Co Ltd Lip cosmetic, candy and chewing gum
US20100309300A1 (en) 2008-09-13 2010-12-09 Rajeshwar Chhibber Method and System for Analyzing Physical Conditions Using Digital Images
JP2017164458A (en) 2016-03-15 2017-09-21 株式会社コーセー Lip dull evaluation method and lip dull evaluation model
CN111840141A (en) 2020-08-13 2020-10-30 广州珈纳生物科技有限公司 A natural antioxidant composition for lips containing astaxanthin

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