JP7751983B2 - Pet Cleaning Composition - Google Patents

Description

The present invention relates to a pet cleaning composition that is mild to the skin, has minimal impact on the body when ingested orally, and is effective in preventing a decline in skin barrier function during cleaning and improving the condition and luster of the coat after drying.

In recent years, with the trend toward nuclear families and smaller families, the number of people keeping pets such as dogs and cats has been increasing. In particular, many pets are kept indoors, resulting in increased contact with pets as people spend their daily lives together. Therefore, maintaining cleanliness by washing with pet cleansers is important for preventing illness and leading a comfortable life. However, pets have delicate skin and are prone to skin diseases, so repeated washing can lead to dry skin. Furthermore, due to their grooming habits, there have been cases where pets accidentally lick cleanser ingredients that have adhered to their fur or skin. In addition, with an increasing number of pet owners seeking to maintain a beautiful appearance, the goal of washing has become not only to maintain cleanliness but also to ensure a clean, dry finish. However, some pets dislike getting wet and can become restless during washing. In response to pet owners' demands for shorter washing times, rinse-in types that provide both a cleansing and a treatment effect have become mainstream. Therefore, there is a demand for safe additives that can provide a rinsing effect in all use scenarios, from washing to drying.

Numerous proposals have been made to solve these problems. Patent Document 1 reports that the inclusion of ceramide improves the skin's barrier function after washing. However, sufficient effects are not always obtained in terms of coat texture and shine, leaving room for improvement. Patent Document 2 reports that a coat treatment composition containing a quaternary ammonium salt improves the finish, but does not report on skin irritation or effects on the body when ingested. Furthermore, the formulation is to be used after applying the cleanser, leaving room for improvement in reducing the burden on the owner who washes the pet.

Patent 4691001 Patent 2541299

We provide a pet cleaning composition that is mild to the skin, has minimal impact on the body when ingested orally, prevents a decline in skin barrier function during cleaning, and is effective in improving the condition and luster of the fur after drying.

The inventors conducted extensive research to solve the above problems and discovered that the use of succinylarginine or a salt thereof prevents the deterioration of skin barrier function that occurs when washing pets, provides unprecedented improvements to the coat condition and shine after drying, is mild to the skin, and has minimal impact on the body when ingested orally, leading to the completion of the present invention.

That is, the present invention is
(1) A pet cleaning composition containing succinylarginine represented by general formula (a) or a salt thereof as component (A).

(2) A pet cleaning composition comprising the pet cleaning composition described in (1) and, as component (B), 1.0 to 15.0% by weight of an N-acylamino acid.

(3) A pet cleaning composition comprising the pet cleaning composition described in (1) and (2) above and containing 1.0 to 10.0% by weight of an amphoteric surfactant as component (C).

(4) A pet cleaning composition comprising the pet cleaning composition described in (1) to (3) above and containing, as component (D), 0.5 to 10.0% by weight of a polyol having 1 to 15 carbon atoms and 2 to 11 oxygen atoms.

By using succinylarginine or a salt thereof, the present invention can provide a pet cleaning composition that is unprecedented in that it is mild to the skin, has minimal impact on the body when ingested orally, prevents a decline in skin barrier function during cleaning, and is effective in improving the condition and luster of the fur after drying.

The present invention will be explained in more detail below using specific examples, but the present invention is not limited to these examples in any way.

The pet cleaning composition of the present invention is a composition containing succinylarginine represented by general formula (a) or a salt thereof as component (A).

Component (A), succinylarginine or its salt represented by general formula (a), is mild to the skin, and even if accidentally ingested orally, it is hydrolyzed in the stomach into arginine and succinic acid, which are used as food additives in supplements and seasonings, so there is little chance of it having an adverse effect on the body.

Succinylarginine or its salts can be produced by known methods (e.g., JP 2016-064994 A). Metal salts such as potassium, calcium, sodium, magnesium, and lithium can be used as salts, with sodium, potassium, and magnesium being generally readily available.

By incorporating succinylarginine or a salt thereof represented by general formula (a), which is component (A), into a cleaning composition, the effects of preventing a decline in skin barrier function after cleaning and improving the coat's texture and shine after drying are achieved. While there are no particular limitations on the amount incorporated, when used as a pet cleaning composition, incorporating 0.1 to 5.0% by weight can simultaneously prevent a decline in skin barrier function and improve the coat's texture and shine after drying. At concentrations below 0.1% by weight, the effects of the present invention may not be realized, while at concentrations exceeding 5.0% by weight, the coat may become stiff after drying.

The surfactant used in the pet cleaning composition of the present invention is not particularly limited, but surfactants that are mild to the skin and have little effect on the body when ingested orally are preferred. For example, N-acyl amino acids can be used as component (B) and amphoteric surfactants can be used as component (C), and these can be used alone or in combination.

The N-acyl amino acids used as component (B) include N-lauroyl-β-alanine, N-lauroyl-N-methyl-β-alanine, N-lauroylsarcosine, N-lauroylglycine, N-lauroylglutamic acid, N-lauroylaspartic acid, N-myristoyl-β-alanine, N-myristoyl-N-methyl-β-alanine, N-myristoylsarcosine, N-myristoylglycine, N-myristoylglutamic acid, N-myristoylaspartic acid, N-coconut fatty acid-β-alanine, and N-coconut fatty acid-N-methyl-β-alanine , N-coconut fatty acid sarcosine, N-coconut fatty acid glycine, N-coconut fatty acid glutamic acid, N-coconut fatty acid aspartic acid, and their salts. In particular, N-lauroyl-N-methyl-β-alanine sodium, N-coconut fatty acid-N-methyl-β-alanine sodium, N-lauroyl sarcosine sodium, N-coconut fatty acid sarcosine sodium, N-coconut fatty acid glutamic acid, and N-coconut fatty acid potassium glutamate are preferred because they have low foaming power and skin irritation, and are said to be less dangerous when ingested orally. These N-acyl amino acids may be used alone or in combination of two or more.

The content of N-acylamino acid (component (B)) in the pet cleaning composition of the present invention is preferably 1.0 to 15.0% by weight. If it is 1.0% by weight or less, the reduced proportion in the composition may cause significant skin irritation from other active agents, while if it is incorporated in an amount exceeding 15.0% by weight, moisture evaporation from the skin may occur more easily, potentially reducing the skin's barrier function. From the perspective of ease of handling when used in a pet cleaning composition, a more preferred content is 3.0 to 13.0% by weight.

Examples of amphoteric surfactants, component (C), include amphoteric surfactants of the amine oxide type, such as amidoamine oxide, amidopropyl betaine, sulfobetaine, imidazoline, and alkylbetaine types. Imidazoline types are particularly preferred because they are said to be less irritating to the skin and less dangerous if ingested orally.

Specific examples of imidazoline-type amphoteric surfactants include sodium cocoamphoacetate (commercially available products include Softazoline (registered trademark) CH, CH-R, CL, and CL-R manufactured by Kawaken Fine Chemicals Co., Ltd.), sodium argan amphoacetate, sodium isostearoamphoacetate, sodium olive amphoacetate, sodium cocoa butter amphoacetate, sodium caproamphoacetate, sodium sesame amphoacetate, sodium rice bran amphoacetate, sodium shea butter amphoacetate, sodium sweet almond amphoacetate, sodium palm amphoacetate, sodium babassu amphoacetate, and sodium peanut amphoacetate. Examples include sodium acetate, sunflower seed sodium amphoacetate, grape seed sodium amphoacetate, mango sodium amphoacetate, cottonseed sodium amphoacetate, sodium lauroamphoacetate (commercially available products include Softazoline LHL and LHL-SF manufactured by Kawaken Fine Chemicals), disodium cocoamphodiacetate, disodium soybean oil fatty acid amphodiacetate, disodium lauroamphodiacetate, sodium cocoamphopropionate (commercially available products include Softazoline NS, SF, and SFD manufactured by Kawaken Fine Chemicals), and disodium cocoamphodipropionate. Due to their ease of availability and excellent foaming power, preferred imidazoline-type amphoteric surfactants include sodium cocoamphoacetate and sodium lauroamphoacetate.

Specific examples of amidoamine oxide-type amphoteric surfactants include lauramidopropylamine oxide (a commercially available product is Softazoline LAO-C manufactured by Kawaken Fine Chemicals Co., Ltd.), cocamidopropylamine oxide, wheat germ oil fatty acid amidopropylamine oxide, soyamidopropylamine oxide, myristamidopropylamine oxide, and milk fat fatty acid amidopropylamine oxide. Specific examples of amine oxide-type amphoteric surfactants include oleamine oxide, cocoamine oxide, dihydroxyethyl cocamine oxide, dihydroxyethyl lauramine oxide, stearamine oxide, decylamine oxide, decyltetradecylamine oxide, behenamine oxide, myristamine oxide, and lauramine oxide.

Specific examples of amphoteric surfactants of the amidopropyl betaine type include cocamidopropyl betaine (commercially available products include Softazoline CPB and CPB-R manufactured by Kawaken Fine Chemicals Co., Ltd.), (capryl/capramido)propyl betaine, isostearamidopropyl betaine, undecylenamidopropyl betaine, oliamidopropyl betaine, oleamidopropyl betaine, shea butter amidopropyl betaine, soyamidopropyl betaine, and palm kernel fatty acid amidopropyl Examples of suitable amphoteric surfactants include propyl betaine (commercially available products include Softazoline PKPB manufactured by Kawaken Fine Chemicals), babassuamidopropyl betaine, myristamidopropyl betaine, meadowfoam amidopropyl betaine, lauramidopropyl betaine (commercially available products include Softazoline LPB and LPB-R manufactured by Kawaken Fine Chemicals), ricinoleic acid amidopropyl betaine, milk fat fatty acid amidopropyl betaine, and horse oil fatty acid amidopropyl betaine. Due to their ease of availability and excellent foaming power, preferred amidopropyl betaine-type amphoteric surfactants include cocamidopropyl betaine and lauramidopropyl betaine.

Specific examples of sulfobetaine-type amphoteric surfactants include lauryl hydroxysulfobetaine (lauryl hydroxysultaine), lauramidopropyl hydroxysultaine, cocamidopropyl hydroxysultaine, erucamidopropyl hydroxysultaine, and methoxycinnamidopropyl hydroxysultaine. Because of their ease of availability and excellent foaming power, preferred sulfobetaine-type amphoteric surfactants include lauryl hydroxysulfobetaine (lauryl hydroxysultaine) and lauramidopropyl hydroxysultaine.

These amphoteric surfactants, component (C), may be used alone or in combination of two or more. Furthermore, when aiming to improve the stability over time and the transparency of the appearance of the pet cleaning composition, it is preferable to use a desalted purified product as component (C).

The content of the amphoteric surfactant (component (C)) in the pet cleaning composition of the present invention is preferably 1.0 to 10.0% by weight. If it is less than 1.0% by weight, the reduced proportion in the composition may cause significant skin irritation from other active agents, while if it is incorporated in an amount exceeding 10.0% by weight, problems with reduced foaming may occur. From the perspective of ease of handling when used in a pet cleaning composition, a more preferred content is 2.0 to 8.0% by weight.

While component (B), the N-acyl amino acid, and component (C), the amphoteric surfactant, are sufficiently low in irritation to the skin when used alone and exhibit excellent surfactant performance, using them in combination further reduces skin irritation and improves ease of handling when used as a pet cleaning composition. For this reason, it is more preferable to use a combination of component (B), the N-acyl amino acid, and component (C), the amphoteric surfactant, in the pet cleaning composition of the present invention.

The polyol component (D) is at least one selected from polyols having 1 to 15 carbon atoms and 2 to 11 oxygen atoms. Specific examples include glycerin derivatives such as glycerin and diglycerin; glycols such as 1,3-butylene glycol, methylene glycol, glycol, diethylene glycol, triethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, pentylene glycol, neopentyl glycol, hexylene glycol, caprylyl glycol, decylene glycol, lauryl glycol, and lauryl glycol hydroxypropyl ether; diols such as propanediol, 1,2-butanediol, 1,4-butanediol, 2,3-butanediol, 1,5-pentanediol, isopentyldiol, hexanediol, 1,2-hexanediol, 1,10-decanediol, ethylhexanediol, octanediol, butylethylpropanediol, and methylpropanediol; sugars such as pentaerythritol, fructose, sorbitol, mannitol, inositol, glucose, lactose, maltitol, and sucrose; and sugar alcohols. In view of their ease of availability and ease of handling, preferred are glycerin, 1,3-butylene glycol, and dipropylene glycol. These components may be used alone or in combination of two or more. Component (D) is preferably incorporated into the pet cleansing composition at 0.5 to 10.0 wt %, more preferably 2.0 to 8.0 wt %. At levels below 0.5 wt %, moisture evaporation from the skin may occur more easily, potentially reducing the barrier function. At levels above 10.0 wt %, reduced foaming may occur.

Water is an optional component that can be added to the pet cleaning composition of the present invention, and may be incorporated by adding water-soluble components.

Other ingredients other than those mentioned above can be added to the pet cleaning composition of the present invention as needed, within qualitative and quantitative ranges that do not substantially impair the effects of the present invention. However, it may be necessary to control the amount of ingredients added that may adsorb to the surface of hair and inhibit the effects of component (A), succinylarginine or a salt thereof. Furthermore, although this will vary depending on the type of pet using the cleaning agent of the present invention, it is undesirable to add ingredients or amounts that may have adverse effects on the pet if they adhere to the pet's hair or skin or if ingested orally.

Other surfactant components that can be added are not particularly limited, but examples of anionic surfactants include laurate, myristate, palmitate, stearate, oleate, coconut oil fatty acid salts, palm kernel oil fatty acid salts, palm oil fatty acid salts, N-lauroyl-N-methyl taurate salts, N-coconut oil fatty acid-N-methyl taurate salts, poly(1-10)oxyethylene lauryl ether acetate, poly(1-10)oxyethylene coconut oil alkyl ether acetate, poly(1-10)oxyethylene tridecyl ether acetate, poly(1-10)oxyethylene lauroylethanolamide ether acetate, poly(1-10)oxyethylene coconut oil fatty acid ethanolamide ether acetate, poly(1-10)N-methyl-lauroylethanolamide ether acetate, poly(1-10)N-ethyl-lauroylethanolamide ether acetate, poly(1-10)oxyethylene N-methyl-coconut oil fatty acid ethanolamide [0033] Examples of the polyoxyethylene methyl ester acetate include poly(1-10)oxyethylene N-ethyl-coconut oil fatty acid ethanolamide ether acetate, poly(0-10)oxyethylene lauryl sulfosuccinate, poly(0-10)oxyethylene coconut oil fatty acid sulfosuccinate, poly(0-10)oxyethylene lauroylethanolamide sulfosuccinate, poly(0-10)oxyethylene coconut oil fatty acid ethanolamide sulfosuccinate, poly(0-10)oxyethylene N-methyl-lauroylethanolamide sulfosuccinate, poly(0-10)oxyethylene N-methyl-coconut oil fatty acid ethanolamide sulfosuccinate, poly(0-10)oxyethylene N-ethyl-lauroylethanolamide sulfosuccinate, poly(0-10)oxyethylene N-ethyl-coconut oil fatty acid ethanolamide sulfosuccinate, and mixtures thereof. Examples of the salts include sodium salts, potassium salts, and triethanolamine salts. Examples of nonionic surfactants include PPG-2 cocamide (available commercially, such as Amizet (registered trademark) 1PC manufactured by Kawaken Fine Chemicals Co., Ltd.), cocamide MEA (available commercially, such as Amizole (registered trademark) CME manufactured by Kawaken Fine Chemicals Co., Ltd.), cocamide DEA (Amizole CDE-G manufactured by Kawaken Fine Chemicals Co., Ltd.), palm kernel oil fatty acid amide DEA (Amizole KD-1 manufactured by Kawaken Fine Chemicals Co., Ltd.), lauramide DEA (Amizole LDE-G manufactured by Kawaken Fine Chemicals Co., Ltd.), (lauramide/myristamide) DEA (Amizole LMDE-Y manufactured by Kawaken Fine Chemicals Co., Ltd.), lauramide MIPA (Amizole PLME-A manufactured by Kawaken Fine Chemicals Co., Ltd.), PEG-3 lauramide (Amizette 2L-Y manufactured by Kawaken Fine Chemicals Co., Ltd.), and (lauryl/myristyl) glycol hydroxypropyl ether. ether (Viscosafe (registered trademark) LMPE manufactured by Kawaken Fine Chemicals Co., Ltd.), cocamide methyl MEA, 2-ethylhexyl glyceryl ether, glyceryl 2-ethylhexanoate, glyceryl (behenate/eicosanedioate), polyglyceryl (behenate/eicosanedioate), alkyl glyceryl ether, alkyl glucoside, alkyl saccharide, ethylene oxide derivative of alkylphenol-formaldehyde condensate, alkyl polyglucoside, alkylene glycol fatty acid esters, polyoxyethylene glyceryl isostearate, isodecyl glyceryl ether, polyethylene glycol ether of diester or triester of oleic acid and methyl glucose, glycerin alkyl ether, glycerin fatty acid ester, PEG-120 methyl glucose dioleate, ethylene glycol distearate Licor, polyethylene glycol dipolyhydroxystearate, sucrose fatty acid esters, sorbitan sesquioleate, ceteareth-60 myristyl glycol, sorbitan monostearate, sorbitan fatty acid esters, sorbitol fatty acid esters, polyoxyethylene sorbitol tetraisostearate, tetraglycerin monolauryl ether, tetrapolyoxyalkylene ethylenediamine condensates, tri(caprylic/capric acid)glyceryl, Pluronic (registered trademark) types, propylene glycol fatty acid esters, pentaerythritol fatty acid esters, polyethylene glycol monooleate, polyethylene glycol-type nonionic surfactants, polyethylene glycol fatty acid esters, polyoxyalkylene/alkyl co-modified organopolysiloxane, polyoxyalkylene alkyl Ethers, polyoxyalkylene alkylphenyl ethers, polyoxyalkylene alkenyl ethers, polyoxyalkylene ethers, polyoxyalkylene esters, polyoxyalkylene glycols, polyoxyalkylene glycol fatty acid esters, polyoxyalkylene glycerin fatty acid esters, polyoxyalkylene dimethyl dimer diol ethers, polyoxyalkylene sorbitan fatty acid esters, polyoxyalkylene sorbitan fatty acid esters, polyoxyalkylene castor oil derivatives, polyoxyalkylene hydrogenated castor oil derivatives, polyoxyalkylene fatty acid amides, polyoxyalkylene fatty acid esters, polyoxyalkylene-modified organopolysiloxanes, polyoxyethylene-POP alkyl ethers, polyoxyethylene alkylamines, polyoxyethylene alkylamines alkyl ether, polyoxyethylene alkyl ethers, polyoxyethylene alkyl thioethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene isostearyl ether, polyoxyethylene-octyldodecyl ether, polyoxyethylene glyceryl cocoate, polyoxyethylene-glycerin monoisostearate, polyoxyethylene glycerin fatty acid esters, polyoxyethylene cholestanol ether, polyoxyethylene cholesteryl ether, polyoxyethylene stanol ether, polyoxyethylene stearyl ether, polyoxyethylene sterol ether, polyoxyethylene cetostearyl hydroxymyristyrene ether, polyoxyethylene sorbitan monofatty acids such as polyoxyethylene sorbitan monolaurate. Acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene-sorbitol monolaurate, polyoxyethylene sorbitol fatty acid esters, polyoxyethylene sorbitol fatty acid esters, polyoxyethylene nonylphenyl ether, polyoxyethylene castor oil, polyoxyethylene phytostanol ether, polyoxyethylene phytosteryl ether, polyoxyethylene phytosterol ether, polyoxyethylene propylene glycol fatty acid esters, polyoxyethylene polyoxypropylene butyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene polyoxypropylene glycols, polyoxyethylene polyoxypropylene glyceryl ethers, polyoxyethylene methyl glucoside, polyoxyethylene PEG-glyceryl coconut oil fatty acid, polyoxyethylene lauryl ether, polyoxyethylene lanolin alcohol, polyoxyethylene lanolin derivatives, polyoxyethylene hydrogenated castor oil, polyoxyethylene hydrogenated castor oil fatty acid esters, polyoxyethylene hydrogenated castor oil derivatives, polyoxyethylene fatty acid esters, polyoxyethylene fatty acid diesters, polyoxysorbitol fatty acid esters, polyoxybutylene, polyoxyethylene, polyoxypropylene glyceryl ethers, polyoxypropylene alkyl ethers, polyoxypropylene diglyceryl ethers, polyoxypropylene monooctyl ether, polyglyceryl ethers, polyglyceryl monoalkyl ethers, polyglycerin alkyl ethers, polyglycerin laurate, polyglycerin fatty acid esters Examples of surfactants include ethers, polysorbates, polypropylene glycol caprylyl ether, monoalkyl glyceryl ethers, monoalkenyl glyceryl ethers, ethylene glycol monooleate, monoglyceride derivatives, monoglycerin alkyl ethers, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monolaurate, PEG-4 laurate, diethylene glycol laurate, propylene glycol laurate, hydrogenated castor oil derivatives, higher fatty acid sucrose esters, fatty acid oxybutylene, fatty acid glycol esters, fatty acid glycerin esters, fatty acid dioxybutylene, block polymers containing fatty alkyl groups, polyhydric alcohol-type nonionic surfactants, polyhydric alcohol fatty acid esters, sugar alcohol fatty acid esters, sugar ethers, and sugar esters.

Other ingredients that can be added include Polyquaternium-10, Polyquaternium-7, Cationic Guar Gum, Polyquaternium-107, Polyquaternium-11, Polyquaternium-22, Polyquaternium-30, Polyquaternium-39, Polyquaternium-4, Polyquaternium-47, Polyquaternium-48, Polyquaternium-49, Polyquaternium-50, Polyquaternium-51, Polyquaternium-52, Polyquaternium Polyquaternium-6, Polyquaternium-61, Polyquaternium-64, Polyquaternium-65, Polyquaternium-67, Polyquaternium-72, Polyquaternium-73, Polyquaternium-92, Cationic Locust Bean Gum, Cationic Tara Gum, Cationic Fenugreek Gum, Cationic Cassia Gum, Cationic Dextran-2, (Aminoethylaminopropylmethicone/Dimethicone) Copolymer, (Divinyldimethicone/Dimethicone) Copolymer Copolymer, (Dimethicone/Vinyl Dimethicone) Crosspolymer, (Meth)Acrylic Silicone Graft Copolymer, (Meth)Acrylic-Modified Silicone, 1,1,1-Triphenyl-3,3-Dialkyl-3-Alkenyldisiloxane, EO-Modified Silicone, PEG/PPG-Dimethicone, PEG-Dimethicone, Acrylic Silicones, Amidoalkyl-Modified Polysiloxane, Silicone with Aminoalkyl Side Chains, Aminoethylaminopropylmethylsiloxane, Aminoglycol-Modified Polysiloxane, Aminophenyl-Modified Polysiloxane, Aminopropyl Dimethicone, Aminopropyltrialkoxysilane, Aminoethylaminopropylmethicone/Dimethicone Copolymer, Aminopropylmethylsiloxane-Dimethylsiloxane Copolymer, Aminopolyether-Modified Silicone, Amino-Modified Silicone, Amino-Modified Silicone-Polyether Block Copolymer, Amodimethicone, Alkyl Alkyl-modified silicone, alcohol-modified silicone, alkoxy-modified silicone, epoxy-modified silicone, epoxyaminosilane copolymer, polysiloxane with oxiranyl or oxetanyl groups, carbinol-modified polysiloxane, carboxy-modified silicone, glyceryl-modified silicone, diphenylpolysiloxane, dimethiconol, dimethicone, dimethicone copolyol, dimethicone copolymer, dimethylsiloxane-methyl (polyoxyethylene) siloxane copolymer, dimethylsiloxane copolymer, silanol-terminated dimethylpolysiloxane, silicone elastomer, silicone quaternium-16/glycidoxy dimethicone crosspolymer, silicone graft polymer, silicone phosphate triester, silicone wax, decyltrisiloxanecarboxylic acid, trimethylsilyl amodimethicone, trimethylsilyl-terminated dimethylpolysiloxane, trimethylsiloxy Silicic acid, panthenylsuccinate silicone quaternium-2, bis(alkoxy) PG amodimethicone, bis(PEG/PPG) dimethicone, biscetearyl amodimethicone, hydroxypropyl polysiloxane hydrolyzed wheat protein, phenyl trimethicone, fluorine-modified silicone, fluoroalkyl group-containing organopolysiloxane, betaine-modified silicone, polyamino-modified silicone, polyether-alkyl co-modified polysiloxane, polyether-modified silicone, polyoxyalkylene-alkyl co-modified silicone, polyoxyalkylene-modified silicone, silicone with polyoxyalkylene side chains, aminopolyether-modified silicone containing polyoxyalkylene structure, polyoxyethylene/polyoxypropylene copolymer-modified polysiloxane, polyglycidol-modified silicone, polyglycerin-alkyl co-modified polysiloxane, polyglycerin-modified polysiloxane, Silicone, methylhydrogenpolysiloxane, methylphenylpolysiloxane, meadowfoam oil fatty acid PEG-dimethicone, mercapto-modified silicone, linoleamidopropyl PG-dimonium chloride phosphate dimethicone, crosslinked organopolysiloxane, crosslinked silicone POA copolymer, crosslinked polyether-modified silicone, crosslinked polyglycerin-modified silicone, highly polymerized amino-modified silicone, highly polymerized dimethicone, highly polymerized dimethyl silicone, low-polymerized dimethyl silicone, highly polymerized methylpolysiloxane, highly polymerized methylpolysiloxane emulsion, silicone polymer with a three-dimensional crosslinked structure, fatty acid-modified silicone, quaternary ammonium group-containing silylated urethane polymer, quaternary cation-modified silicone, long-chain alkyl-modified acrylate silicone, linear aminopolyether-modified silicone, linear aminopolyether-modified polysiloxane, non-emulsifying crosslinked type, partially crosslinked Silicones such as organopolysiloxane polymer silicone, sugar derivatives such as hydroxyalkylated cyclodextrin, hydroxypropyl cellulose, acylated pullulan, stearoxyhydroxypropylmethylcellulose, allitol, talitol, and trehalose isostearate, trehalose, hyaluronic acid, acetylated hyaluronic acid, collagen, carboxymethylchitosan succinamide, PPG-2 arginine, sodium dilauramidoglutamide lysine, amidinoproline, mulberry milk, honey, pyrrolidonecarboxylic acids, glucosamines, alanylglutamine, glyceryl-N-(2-hydroxyethyl)carbamate, and glucamines, water-soluble moisturizing oils such as PEG/PPG/polybutylene glycol-8/5/3 glycerin, diglucosyl gallic acid, glycylglycine, panthenol, cationized hydroxypropyl cellulose, carnitine, proteoglycans, etc. Hair conditioners such as compounds containing a phosphorylcholine analogue group obtained by ring-opening an intermediate obtained by reacting a higher alcohol with 2-chloro-2-oxo-1,3,2-dioxaphospholane in the presence of an organic base with dimethylalkylamine, polyelectrolytes such as poly(styrenesulfonate) sodium salt and poly(diallyldimethylammonium chloride), (ammonium acryloyldimethyltaurate/beheneth methacrylate) crosspolymer, (PEG/decyltetradeceth/HDI) copolymer, xanthan gum, carboxymethylcellulose, sodium carboxymethylcellulose, polymethacryloyloxyethyl phosphorylcholine, quaternary ammonium group-containing silylated urethane polymer, (sodium acrylate/acryloyldimethyltaurate) Polymers such as (methacryloyloxyethyl)phosphorylcholine sodium copolymer, (styrene/acrylates/methacrylic acid) copolymer, carboxyvinyl polymer, phosphorylcholine group-containing polymer, phosphate-crosslinked starch derivative, hydroxypropyl starch phosphate, polystyrene sodium sulfonate, (methacryloylethyl dimethylbetaine/methacryloylethyltrimethylammonium chloride/methoxypolyethylene glycol methacrylate) copolymer, alkyl acrylate/alkyl methacrylate/polyoxyethylene copolymer, polymethoxypolyethylene glycol methacrylate, methacrylic copolymer, hydrogenated polyisobutene, 2-methacryloyloxyethyl phosphorylcholine/butyl methacrylate copolymer, polyuronic acid, 2-((meth)acryloyloxy)ethyl-2'-(trimethylammonio)ethyl phosphate polymer, lactones such as gamma-docosalactone, gluconolactone, and erucalactone,

Cetyl 2-ethylhexanoate, di-2-heptylundecyl adipate, diglyceryl adipate mixed fatty acid ester, isostearyl isostearate, octyldodecyl isostearate, phytosteryl isostearate, propylene glycol isostearate, isodecyl benzoate, isotridecyl isononanoate, isononyl isononanoate, polyglyceryl eicosandioate/tetradecanedioate, cetyl octanoate, ethyl olivate, ethyl oleate, phytosteryl oleate glyceryl, di-2-ethylhexyl succinate, diethylhexyl succinate, bis(diethylene glycol ethyl ether) succinate, diglyceryl diisostearate, propylene glycol dicaprylate, neopentyl glycol dicaprate, tripropylene glycol dineopentanoate, esters of dipentaerythritol and mixed fatty acids such as hydroxystearic acid/stearic acid/rosin acid, dilinoleic acid di(phytostearyl/isostearyl/cetyl/stearyl/behenyl), stearyl Isocetyl acrylate, stearyl stearate, hydrogenated castor oil stearate, diethyl sebacate, diethyl sebacate, dextrin fatty acid ester, pentaerythrityl tetra-2-ethylhexanoate, pentaerythritol tetra-2-ethylhexanoate, caprylic/capric triglyceride, glyceryl tri-2-ethylhexanoate, triethylhexanoin, isodecyl neopentanoate, isopropyl palmitate, ethylhexyl palmitate, octyl palmitate, hydroxystearyl Ester oils such as hydrogenated castor oil, phytosteryl isostearate, isopropyl myristate, octyldodecyl myristate, myristyl myristate, diisostearyl malate, etc., isopropyl lauroyl sarcosinate, lauroyl glutamate (phytosteryl/behenyl/octyldodecyl/isostearyl), di(cholesteryl/behenyl/octyldodecyl) lauroyl glutamate, diisostearyl lauroyl glutamate, dioctyldodeceth-2 lauroyl glutamate acyl amino acid esters such as disteareth-2 lauroyl glutamate, dihexyldecyl lauroyl glutamate, and myristoylmethyl-β-alanine (phytosteryl/decyltetradecyl); branched fatty acids such as 18-methyleicosanoic acid, 14-methylpentadecanoic acid, 14-methylhexadecanoic acid, 15-methylhexadecanoic acid, 15-methylheptadecanoic acid, 16-methylheptadecanoic acid, 16-methyloctadecanoic acid, 17-methyloctadecanoic acid, and 17-methylnonadecanoic acid; and its ester oils, lanolin fatty acids and their salts and other extracts from lanolin, sphingosine, natural ceramides or natural ceramides and their derivatives, camellia oil, macadamia nut oil, corn oil, olive oil, avocado oil, castor oil, safflower oil, jojoba oil, sunflower oil, rapeseed oil, sesame oil, soybean oil, meadowfoam oil, lavender oil, eucalyptus oil, geranium oil, cypress oil, rose oil, carbanum oil, pepper oil, basil oil, palm rosa oil, pine needle oil, ylang ylang oil, peach Natural oils such as grain oil, thyme oil, chamomile oil, acai palm fruit oil, argan oil, baobab oil, and orange roughy oil; hydrogenated oils such as hydrogenated coconut oil, hydrogenated palm oil, hydrogenated castor oil, hydrogenated rapeseed oil, hydrogenated palm oil, and hydrogenated jojoba oil; hydrocarbon oils such as liquid paraffin, liquid isoparaffin, petrolatum, squalene, squalane, 2,2,4,6,6-pentamethylheptane, and terpenes; aloe vera extract, Scutellaria root extract, Panax ginseng extract, persimmon tannin extract, rose hip extract, chamomile flower extract, and se White Lamium Extract, Pear Branch Extract, Centifolia Rosa Extract, Tea Leaf Extract, Heart Flower Extract, Witch Hazel Extract, Tilia Cordata Extract, Mulberry Extract, Cornflower Extract, Yuzu Extract, Roman Chamomile Extract, Royal Jelly Extract, Zanthoxylum Pepper Extract, Hinoki Extract, Hop Extract, Gentian Extract, Japanese Anemone Extract, Kiwi Extract, Hawthorn Extract, Apple Extract, Alpinia Katsumadai Seed Extract, Ginger Extract, Adzuki Bean Seed Extract, Althaea Extract, Se Extracts such as rice bran fermented extract, milk thistle extract, white willow extract, grapefruit extract, and amur extract, turmeric extract, ginseng extract, fucus extract, beech bud extract, rice bran extract, camellia extract, peach kernel extract, sophora flavescens extract, chlorella extract, marjoram extract, jasmine extract, shell ginger leaf extract, broccoli extract, balsam extract, horse chestnut extract, licorice extract, butcher's broom extract, mimosa pudica extract, Inomoto extract Saw extract, clary sage extract, juniper berry extract, honeysuckle extract, lockjaw extract, leaf mold extract, saffron extract, manuka extract, Job's tears seed extract, soybean seed extract, pomegranate flower extract, yuzu fruit extract, Job's tears seed extract, soybean seed extract, pomegranate extract, yuzu extract, coffee tree extract, Himalayan bergamia extract, plum extract, bilberry extract, tea extract, extract obtained from fermented fruits of grass plants, fermented soybean extract, brown algae extract, star anise extract Extracts of thorny pear, wild rose extract, giant germ rice fermented brown rice extract, extract of rose petals and pistils containing placenta, mangosteen extract, fleabane extract, curry plant extract, ginkgo extract, ginger extract, calendula extract, quince seed extract, longan extract, apricot extract, pecan extract, sunshine cherry extract, cat's whiskers extract, black raspberry extract, Himalayan raspberry extract, walnut extract, Diarrhea indica extract, Phellodendron bark extract, Coptis japonica extract, cup Natural extracts such as root extract, Lithospermum root extract, Peony extract, Swertia japonica extract, Birch extract, Sage extract, Loquat extract, Carrot extract, Aloe extract, Mallow extract, Iris extract, Grape extract, Job's tears extract, Luffa extract, Lily extract, Saffron extract, Cnidium extract, Ginger extract, St. John's wort extract, Rosemary extract, Garlic extract, Chili pepper extract, Burnt extract, etc. Protein or hydrolysate thereof obtained from nacreous shells or pearls, protein or hydrolysate thereof obtained from silk, protein-containing extract obtained from legume seeds, zinc pyrithione, trichlorocarbanilide, sulfur, dipotassium glycyrrhizinate, benzalkonium chloride and other antidandruff agents, glyoxylic acid, glyoxylic acid hydrate, glyoxylates, glyoxylamide and other antistatic agents, thickeners, viscosity adjusters, lower alcohols such as ethanol, surfactants such as naphthalenesulfonic acid, emulsifiers, milk Opacifying agents, phytic acid and other sequestering agents, UV absorbers, sulforaphane, nicotinamide, tannic acid, arginyl flucotosyl glucose, tocopheryl retinoate, polyphenols and other antioxidants, preservatives, powder ingredients, urethane resins, hydrophobically modified polyether urethanes, polyurethane gels and other urethanes, blood circulation promoters, local stimulants, hair follicle activators, hair nutrients, antiseborrheic agents, anti-aging agents, emollients, keratolytic agents, glycyrrhetinic acid, cholesterol, phytosterols, retinol Retinol, retinol acetate, retinol palmitate, menthol, alkoxysalicylic acid, salicylic acid, astaxanthin, N-benzoylglycylglycine, humic acid, fulvic acid, 1-indanylidene derivatives, allantoin, glycosaminoglycans, beeswax, candelilla wax, polyglutamic acids, nicotinic acids, phosphoserine, stigmasterol, oleanolic acid, trehangerin, tocopheryl phosphate, ascorbyl ethyl, flavanones, costunolide, dehydrocostus lactone, astaxanthin These include skin conditioning agents such as corbic acid-2-phosphate-6-fatty acid, whey, glycerophosphocholine, glucoheptonic acid, and glyceryl-1-octadecylurethane, disinfectants such as miconazole, preservatives, anti-inflammatory agents, anti-inflammatory agents such as tranexamic acid, cooling agents, amino acids, vitamins such as tocopherol, ascorbic acid, and glucopyranosyl ascorbic acid, vitamin derivatives, herbal extracts, deep sea water, pigments, dyes such as ultramarine, coloring materials, dyes such as melanin precursors, and fragrances.

It is generally known that there is a correlation between pH and viscosity for some cleaning compositions. The pet cleaning composition of the present invention can also be adjusted to the desired viscosity by adjusting the pH using a pH adjuster using known techniques, and can be adjusted to the desired viscosity, from a low-viscosity solution to a high-viscosity gel. Examples of pH adjusters that can be used include citric acid, succinic acid, malic acid, lactic acid, tartaric acid, glycolic acid, glucuronic acid, and sodium hydroxide. While there are no particular limitations on the pH of the pet cleaning composition of the present invention, a pH of 5.0 to 8.0 at 25°C is desirable for the undiluted solution from the standpoints of foaming during cleaning, low-temperature stability, and skin irritation. At a pH below 5.0, the anionic surfactant falls below its pKa, reducing its surfactant activity and resulting in reduced foaming and poor low-temperature stability. At a pH above 8.0, alkali-induced skin damage may occur.

The effects of the present invention will be explained in more detail using the following examples, but the present invention is not limited to these examples.

Test Methods Cleaning compositions having the compositions shown in Tables 1 and 2 were prepared according to known methods to obtain cleaning compositions of Examples 1 to 13 and Comparative Examples 1 and 2. The resulting cleaning compositions were evaluated as follows, and the results are shown in Tables 1 and 2.

Evaluation Method Five healthy, long-haired dogs (Maltese) and five long-haired cats (Persian) with no skin abnormalities were washed twice a week for four weeks using 30 to 50 g of the pet cleaning composition (Products 1 to 13 of the present invention, and Comparative Products 1 and 2). After that, various evaluations were carried out according to the following evaluation criteria. The average score for the 10 dogs was calculated, and the average score was evaluated as follows: 5 to 4.6 = ★, less than 4.6 to 4.1 = ☆, less than 4.1 to 3.6 = ◎, less than 3.6 to 3.1 = ○, less than 3.1 to 2.5 = △, and less than 2.5 to 1 = ×.

<Method for determining the effect of preventing a decline in skin barrier function>
The skin condition of the long-haired dogs and cats that were the subjects of this evaluation after hair removal was visually observed once a day during the evaluation period by five expert panelists and evaluated based on the following evaluation criteria. The lowest evaluation score during the evaluation period was recorded as the score for the subject.
5: No erythema or dryness is observed 4: Almost no erythema or dryness is observed 3: Neither 2: Slight erythema or dryness is observed 1: Erythema and dryness are observed

<How to judge coat condition>
Immediately after the 4-week repeated use, the coat was towel-dried and then dried with a hairdryer, and the coat was visually inspected by five expert panelists and evaluated according to the following evaluation criteria.
5: Excellent quality of fur 4: Fairly good quality of fur 3: Unclear 2: Fairly poor quality of fur 1: Poor quality of fur

<How to judge coat gloss>
Immediately after the 4-week repeated use, the coat gloss after towel drying and drying with a hairdryer was visually observed by five expert panelists and evaluated according to the following evaluation criteria.
5: Excellent coat gloss 4: Slightly excellent coat gloss 3: Neither 2: Slightly inferior coat gloss 1: Poor coat gloss

Pet Cleaning Composition Examples
*1: Kawatect (registered trademark) SAS (Kawaken Fine Chemical Co., Ltd. 30% by weight aqueous solution), *2: Alanon (registered trademark) ALE (Kawaken Fine Chemical Co., Ltd.), *3: Soypon (registered trademark) SLE (Kawaken Fine Chemical Co., Ltd.), *4: Aminosurfact (registered trademark) ACDS-L (Asahi Kasei Finechem Co., Ltd.), *5: Softazoline CPB-R (Kawaken Fine Chemical Co., Ltd.), *6: Anhithol (registered trademark) 20HD (Kao Corporation), *7: Softazoline CH-R (Kawaken Fine Chemical Co., Ltd.), *8: Amizet 1PC (Kawaken Fine Chemical Co., Ltd.) Fine Chemical Co., Ltd.), *9: Aminone (registered trademark) C-11S (Kao Corporation), *10: Emal (registered trademark) E-27C (Kao Corporation), *11: NIKKOL (registered trademark) CMT-30 (Nikko Chemicals), *12: Catinal (registered trademark) HC-200 (Toho Chemical Industry Co., Ltd.), *13: Lipoflow (registered trademark) MN (Lion Specialty Chemicals Co., Ltd.), and other raw materials were special grade or first grade reagents manufactured by Fujifilm Wako Pure Chemical Industries, Ltd. pH adjustment was also performed using citric acid or sodium hydroxide reagents manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.

Pet Cleaning Composition Examples and Comparative Examples

Evaluation Results Examples 1 to 13, which were prepared within the scope of the pet cleaning composition of the present invention, were all rated as good or better, confirming that they were mild to the skin, prevented a decline in skin barrier function due to cleaning, and at the same time improved the coat's texture and shine after drying.
On the other hand, in Comparative Examples 1 and 2, which did not contain component (A), the effects of preventing a decrease in skin barrier function, and the evaluations of coat condition and coat gloss were rated as fair or lower, and the characteristic effects of the present invention were not fully achieved.

The pet cleaning composition of the present invention is mild to the skin, has little effect on the body when ingested orally, prevents a decrease in skin barrier function due to cleansing, and improves the coat condition and luster of the coat simply by cleansing, thereby increasing the commercial value of pet care products such as pet cleansers.

Claims (1)

Succinylarginine represented by general formula (a) or a salt thereof ;
1.0 to 15.0% by weight of an N-acylamino acid,
1.0 to 10.0% by weight of an amphoteric surfactant,
A pet cleaning composition containing 0.5 to 10.0% by weight of a polyol having 1 to 15 carbon atoms and 2 to 11 oxygen atoms .