JP7828764B2 - automatic analyzer - Google Patents

Description

The embodiments disclosed herein and in the drawings relate to automated analyzers.

An automated analyzer is a device that analyzes the components of a test sample corresponding to each test item by mixing a sample, such as blood collected from a subject or a standard sample for each test item, with reagents corresponding to each test item, and then measuring the resulting mixture, for example, optically.

Conventionally, in automated analyzers, the light intensity of the light-emitting section used for optical measurement is adjusted by inserting multiple light intensity measuring jigs into the reaction disk where the reaction tube is installed, and then adjusting the light intensity of the multiple light-emitting sections provided on the reaction disk. However, when multiple light intensity measuring jigs are used, the light intensity obtained from the light-emitting section is affected by individual differences in the light intensity measuring jigs, which can lead to variations in the adjusted light intensity and potentially inconsistencies in the optical measurement results of the mixed solution. Therefore, it is desirable to transport a single light intensity measuring jig to the reaction disk, measure the light intensity of the light-emitting sections provided on the reaction disk, and then adjust the light intensity of each light-emitting section.

Furthermore, in automated analyzers that use disposable reaction tubes, all disposable reaction tubes supplied by the reaction tube supply unit are placed on the reaction disk and used for optical measurement of the mixed solution. However, some disposable reaction tubes supplied by the reaction tube supply unit may contain dust, chips, or/or cracks. If such reaction tubes are used for measurement, accurate measurement results may not be obtained. Therefore, it is desirable to determine whether a reaction tube can be used for optical measurement before using it for optical measurement if it contains dust or other defects, and to refrain from using reaction tubes that are deemed unsuitable for optical measurement.

Japanese Patent Publication No. 2014-145621 Special Publication No. 63-21139 Japanese Patent Publication No. 2017-26548

One of the problems that the embodiments disclosed herein and in the drawings aim to solve is to improve the measurement accuracy of an automated analyzer. However, the problems that the embodiments disclosed herein and in the drawings aim to solve are not limited to the above problem. Problems corresponding to the effects of each configuration shown in the embodiments described later can also be positioned as other problems.

The automated analyzer according to this embodiment comprises: a reaction tube installation section where reaction tubes are installed; a reaction tube transport mechanism for transporting the reaction tubes; an imaging unit provided on the reaction tube transport mechanism; and a first control unit that controls the reaction tube transport mechanism to transport the reaction tubes to the reaction tube installation section and to image the reaction tubes with the imaging unit.

A block diagram showing an example of the functional configuration of an automated analyzer according to the first embodiment. Figure 1 shows an example of the configuration of the analytical mechanism in the automated analyzer. Figure 2 shows a top view of the photometric unit included in the analysis mechanism. Figure 2 shows a top view of the photometric unit included in the analysis mechanism. Figure 2 shows another example of the photometric unit included in the analysis mechanism, as viewed from above. A flowchart illustrating the contents of the measurement process performed by the automated analyzer according to the first embodiment. A schematic diagram illustrating an example of the relationship between the light-receiving position of the imaging unit and the optical axis height of the light-emitting unit in an automated analyzer according to the first embodiment. A flowchart illustrating the contents of the measurement process performed by the automated analyzer according to Modification 1 of the First Embodiment. A flowchart illustrating the contents of the measurement process performed by the automated analyzer according to Modification 1 of the First Embodiment. A schematic diagram illustrating an example of the relationship between the amount of descent of the light intensity measuring jig and the optical axis height of the light-emitting part in an automatic analyzer according to Modification 1 of the first embodiment. A block diagram showing an example of the functional configuration of an automated analyzer according to the second embodiment. Figure 11 shows an example of the configuration of the analytical mechanism in the automated analyzer. A flowchart illustrating the contents of the reaction tube imaging process performed by the automated analyzer according to the second embodiment. A schematic diagram showing an example of a case in which the reaction tube is determined to be unusable in the automated analyzer according to the second embodiment. A block diagram showing an example of the functional configuration of an automated analyzer according to the third embodiment. Figure 15 shows an example of the configuration of the analytical mechanism in an automated analyzer. A flowchart illustrating the contents of the used reaction tube imaging process performed by the automated analyzer according to the third embodiment. A schematic diagram showing an example of a case where there is an abnormality in the used reaction tube in the automated analyzer according to the third embodiment.

The following describes an embodiment of the automated analyzer with reference to the drawings. In the following description, components having substantially the same function and configuration will be denoted by the same reference numeral, and redundant explanations will be provided only when necessary.

[First Embodiment]
Figure 1 is a block diagram showing an example of the functional configuration of an automated analyzer according to the first embodiment. In this embodiment, the automated analyzer is, for example, a blood coagulation analyzer. As shown in Figure 1, the automated analyzer 1 according to this embodiment is configured to include an analysis mechanism 2, an analysis circuit 3, a drive mechanism 4, an input interface 5, an output interface 6, a communication interface 7, a memory circuit 8, and a control circuit 9.

Analysis device 2 generates a mixture of the subject's blood sample and the coagulation reagent used for each test item. Depending on the test item, analysis device 2 also mixes a standard solution diluted to a predetermined ratio with the reagent used for that test item. Analysis device 2 continuously measures the optical properties of the blood sample-reagent mixture and the standard solution-reagent mixture. This measurement generates standard data, expressed as, for example, transmitted light intensity, absorbance, scattered light intensity, etc., as well as the subject data.

The analysis circuit 3 is a processor that generates calibration data and analysis data related to blood sample coagulation by analyzing the standard data and test data generated by the analysis mechanism 2. For example, the analysis circuit 3 reads an analysis program from the memory circuit 8 and analyzes the standard data and test data according to the read analysis program. The analysis circuit 3 may also include a memory area for storing at least a portion of the data stored in the memory circuit 8.

The drive mechanism 4 drives the analysis mechanism 2 according to the control of the control circuit 9. The drive mechanism 4 is implemented, for example, by gears, a stepping motor, a belt conveyor, and a lead screw.

The input interface 5 receives settings for analysis parameters of various test items related to blood samples, for example, requested by the user or via the hospital network (NW). The input interface 5 is implemented using, for example, a mouse, keyboard, or touchpad, where instructions are input by touching the operating surface. The input interface 5 is connected to the control circuit 9, converts user input instructions into electrical signals, and outputs these electrical signals to the control circuit 9. In this specification, the input interface 5 is not limited to those equipped with physical operating components such as a mouse and keyboard. For example, an electrical signal processing circuit that receives electrical signals corresponding to operation instructions input from an external input device separate from the automatic analyzer 1 and outputs these electrical signals to the control circuit 9 is also included as an example of the input interface 5.

The output interface 6 is connected to the control circuit 9 and outputs signals supplied from the control circuit 9. The output interface 6 is implemented by, for example, a display circuit, a printing circuit, and an audio device. The display circuit includes, for example, a CRT display, a liquid crystal display, an organic EL display, an LED display, and a plasma display. A processing circuit that converts data representing the display target into a video signal and outputs the video signal externally is also included in the display circuit. The printing circuit includes, for example, a printer. An output circuit that outputs data representing the print target externally is also included in the printing circuit. The audio device includes, for example, a speaker. An output circuit that outputs an audio signal externally is also included in the audio device.

The communication interface 7 connects, for example, to the hospital network NW. The communication interface 7 communicates data with the HIS (Hospital Information System) via the hospital network NW. Alternatively, the communication interface 7 may communicate data with the HIS via the Laboratory Information System (LIS), which is connected to the hospital network NW.

The memory circuit 8 is composed of a magnetic or optical recording medium, or a semiconductor memory, or other recording medium that can be read by the processor. Note that the memory circuit 8 does not necessarily need to be implemented using a single storage device. For example, the memory circuit 8 can be implemented using multiple storage devices.

Furthermore, the memory circuit 8 stores the analysis program executed by the analysis circuit 3 and the control program for realizing the functions of the control circuit 9. The memory circuit 8 stores the calibration data generated by the analysis circuit 3 for each test item. The memory circuit 8 stores the analysis data generated by the analysis circuit 3 for each blood sample. The memory circuit 8 stores test orders entered by the user, or test orders received by the communication interface 7 via the hospital network NW.

The control circuit 9 is a processor that functions as the central hub of the automatic analysis device 1. The control circuit 9 executes the operation program stored in the memory circuit 8, thereby realizing the functions corresponding to this program. The control circuit 9 may also include a memory area for storing at least a portion of the data stored in the memory circuit 8.

Figure 2 shows an example of the configuration of the analysis mechanism 2 in the automated analyzer 1 shown in Figure 1. As shown in Figure 2, the analysis mechanism 2 according to this embodiment is configured to include a reaction disk 201, a constant temperature unit 202, a rack sampler 203, and a reagent storage unit 204.

The reaction disk 201 holds multiple reaction tubes (cuvettes) 2011 arranged in a ring shape. The reaction disk 201 transports the reaction tubes 2011 along a predetermined path. Specifically, during sample analysis, the reaction disk 201 is rotated and stopped alternately at predetermined time intervals by the drive mechanism 4. The reaction tubes 2011 are formed, for example, from polypropylene (PP) or acrylic. This reaction disk 201 constitutes the reaction tube mounting section in this embodiment.

The constant temperature unit 202 stores a heat transfer medium set to a predetermined temperature and raises the temperature of the mixture contained in the reaction tube 2011 by immersing the reaction tube 2011 in the stored heat transfer medium.

The rack sampler 203 provides movable support for a sample rack 2031 capable of holding multiple sample containers. These sample containers contain blood samples, which are specimens requested for measurement. Figure 2 shows an example where the sample rack 2031 can hold five sample containers in parallel.

The rack sampler 203 is provided with a transport area 2032 for transporting sample racks 2031. That is, using this transport area 2032, the sample racks 2031 are transported from the input position where they are placed to the retrieval position where the sample racks 2031 are collected after measurement is complete. In the transport area 2032, multiple sample racks 2031, aligned in the longitudinal direction, are moved in direction D1 by the drive mechanism 4.

Furthermore, the rack sampler 203 is provided with a retraction area 2033 for retracting the sample rack 2031 from the transport area 2032 in order to move the sample container held by the sample rack 2031 to a predetermined sample aspiration position. The sample aspiration position is, for example, located at the intersection of the rotational trajectory of the sample dispensing probe 207 and the movement trajectory of the opening of the sample container supported by the rack sampler 203 and held by the sample rack 2031. In the retraction area 2033, the transported sample rack 2031 is moved in direction D2 by the drive mechanism 4.

Furthermore, the rack sampler 203 is provided with a return area 2034 for returning the sample rack 2031, which holds the sample container with the sample aspirated, to the transport area. In the return area 2034, the sample rack 2031 is moved in direction D3 by the drive mechanism 4.

The reagent cabinet 204 holds multiple reagent containers 100 containing standard solutions and reagents used in various tests performed on blood samples, while maintaining their temperature. A rotating table is rotatably mounted inside the reagent cabinet 204. The rotating table holds the multiple reagent containers 100 in a circular arrangement. Although not shown in Figure 2, in this embodiment, the reagent cabinet 204 is covered by a removable reagent cover.

Furthermore, the analytical mechanism 2 according to this embodiment, shown in Figure 2, comprises a sample dispensing arm 206, a sample dispensing probe 207, a reagent dispensing arm 208, and a reagent dispensing probe 209.

The sample dispensing arm 206 is positioned between the reaction disk 201 and the rack sampler 203. The sample dispensing arm 206 is mounted by a drive mechanism 4 so as to be vertically movable and horizontally rotatable. The sample dispensing arm 206 holds a sample dispensing probe 207 at one end.

The sample dispensing probe 207 rotates along an arc-shaped rotational trajectory as the sample dispensing arm 206 rotates. A sample aspiration position is provided along this rotational trajectory for aspirating a sample from a sample container held by the sample rack 2031 on the rack sampler 203. Furthermore, a sample dispensing position is provided along the rotational trajectory of the sample dispensing probe 207 for dispensing the sample aspirated by the sample dispensing probe 207 into the reaction tube 2011. The sample dispensing position corresponds, for example, to the intersection of the rotational trajectory of the sample dispensing probe 207 and the movement trajectory of the reaction tube 2011 held on the reaction disk 201.

The sample dispensing probe 207 is driven by the drive mechanism 4 and moves vertically at the sample aspiration position or the sample dispensing position. The sample dispensing probe 207 also aspirates a sample from the sample container located directly below the sample aspiration position, according to the control circuit 9. Furthermore, the sample dispensing probe 207 dispenses the aspirated sample into the reaction tube 2011, also according to the control circuit 9. These sample dispensing arm 206 and sample dispensing probe 207 constitute an example of the dispensing mechanism in this embodiment.

The reagent dispensing arm 208 is positioned between the reaction disk 201 and the reagent storage compartment 204. The reagent dispensing arm 208 is mounted by a drive mechanism 4 so as to be vertically movable and horizontally rotatable. The reagent dispensing arm 208 holds a reagent dispensing probe 209 at one end.

The reagent dispensing probe 209 rotates along an arc-shaped rotational trajectory as the reagent dispensing arm 208 rotates. A reagent aspiration position is provided on this rotational trajectory. For example, the reagent aspiration position is located where the rotational trajectory of the reagent dispensing probe 209 intersects with the movement trajectory of the opening of the reagent container 100, which is placed in an annular shape on the rotating table of the reagent storage unit 204. Furthermore, a reagent dispensing position is set on the rotational trajectory of the reagent dispensing probe 209 for dispensing the reagent aspirationd by the probe 209 into the reaction tube 2011. For example, the reagent dispensing position corresponds to the intersection of the rotational trajectory of the reagent dispensing probe 209 and the movement trajectory of the reaction tube 2011 held on the reaction disk 201.

The reagent dispensing probe 209 is driven by the drive mechanism 4 and moves vertically at the reagent aspiration position or reagent dispensing position on its rotational trajectory. The reagent dispensing probe 209 also aspirates reagent from the reagent container stopped at the reagent aspiration position, according to the control circuit 9. Furthermore, the reagent dispensing probe 209 dispenses the aspirated reagent into the reaction tube 2011 located directly below the reagent dispensing position, also according to the control circuit 9.

Furthermore, the analysis mechanism 2 according to this embodiment includes a reaction tube transport arm 210, a reaction tube supply unit 211, and a light intensity measurement jig 212.

The reaction tube transport arm 210 transports the reaction tube 2011 from the reaction tube supply unit 211 to the reaction disk 201 by the drive mechanism 4. For example, the reaction tube transport arm 210 includes a reaction tube holding unit 2101 for holding the reaction tube 2011, and a transport arm 2102 for rotating and moving the reaction tube holding unit 2101 up and down. The reaction tube transport arm 210 is also provided with an imaging unit 2103 for imaging the reaction tube 2011. The reaction tube holding unit 2101 is, for example, a gripper. The transport arm 2102 is provided by the drive mechanism 4 so as to be able to move up and down vertically and rotate horizontally. The imaging unit 2103 images the reaction tube 2011 according to the control of the control circuit 9. The imaging unit 2103 is also, for example, an imaging sensor used for measuring light intensity, etc. Note that the imaging unit 2103 may be an imaging device such as a camera. Note that the reaction tube transport arm 210 is just one example of a reaction tube transport mechanism. Furthermore, the number of transport arms 2102 constituting the reaction tube transport arm 210 is arbitrary. For example, the reaction tube transport arm 210 may be composed of two or more transport arms.

In this embodiment, the reaction tube transport arm 210 transports the reaction tube 2011 from the reaction tube supply unit 211 to the reaction tube installation position on the reaction disk 201, such that the reaction tube holding unit 2101 of the reaction tube transport arm 210, and the reaction tube 2011 held by the reaction tube holding unit 2101 or the light intensity measuring jig 212 held by the reaction tube holding unit 2101, pass through the transport path. Furthermore, the transport path of the reaction tube 2011 or the light intensity measuring jig 212 held by the reaction tube holding unit 2101 of the reaction tube transport arm 210 is formed, for example, on an arc-shaped rotational trajectory associated with rotation around one end of the transport arm 2102. The reaction tube installation position on the reaction disk 201 is, for example, the position where the rotating trajectory, which is the transport path for the reaction tube 2011 on the reaction disk 201, intersects with the rotating trajectory, which is the transport path for the reaction tube 2011 or the light intensity measuring jig 212 held by the reaction tube holding unit 2101. The reaction tube 2011 or the light intensity measuring jig 212, transported by the reaction tube transport arm 210, is installed at the reaction tube installation position on the reaction disk 201.

The transport path for the reaction tube 2011 or the light intensity measuring jig 212, held by the reaction tube holding section 2101 of the reaction tube transport arm 210, is arbitrary. For example, the transport path for the reaction tube 2011 or the light intensity measuring jig 212, held by the reaction tube holding section 2101 of the reaction tube transport arm 210, may be formed on an elliptical trajectory, or it may be a transport path without a specific shape.

The reaction tube supply unit 211 supplies empty reaction tubes 2011. The reaction tube supply unit 211 is located near the outer circumference of the reaction disk 201. The reaction tube supply unit 211 is configured, for example, with a reaction tube housing unit 2111 and a reaction tube supply rail 2112. The reaction tube housing unit 2111 houses, for example, a plurality of empty reaction tubes 2011. The reaction tube housing unit 2111 supplies empty reaction tubes 2011 to the reaction tube supply rail 2112 by the control circuit 9. The reaction tube supply rail 2112 is, for example, inclined toward the reaction tube supply position from the reaction tube housing unit 2111. Therefore, the reaction tubes 2011 slide along the reaction tube supply rail 2112 due to gravity and move toward the reaction tube supply position. The reaction tube supply position is, for example, the position where the rotational trajectory, which is the transport path of the reaction tube 2011 in the reaction tube holding section 2101 of the reaction tube transport arm 210, intersects with the movement trajectory of the reaction tube 2011 on the reaction tube supply rail 2042.

The light intensity measurement jig 212 is a jig used to measure the light intensity and optical axis height of the light-emitting part of the photometric unit described later. The light intensity measurement jig 212 is composed of, for example, a mirror 2121 and a mirror housing container 2122. The mirror 2121 is a component that reflects light emitted from the light-emitting part and guides it to the imaging unit 2103 of the reaction tube transport arm 210. Note that the component that reflects light emitted from the light-emitting part and guides it to the imaging unit 2103 of the reaction tube transport arm 210 is not limited to a mirror; it may be a reflective component that reflects light, such as a prism. The mirror housing container 2122 is a container for housing the mirror 2121 and, for example, has the same shape as the reaction tube 2011.

In this embodiment, the light intensity measurement jig 212 is installed, for example, at the jig installation position of the analysis mechanism 2. This jig installation position is located on the rotational track, which is the transport path of the reaction tube holding section 2101 of the reaction tube transport arm 210. In this embodiment, the light intensity measurement jig 212 is installed at the jig installation position of the analysis mechanism 2, but it does not necessarily have to be installed at the jig installation position of the analysis mechanism 2. That is, the installation location of the light intensity measurement jig 212 is arbitrary; for example, it may be installed (stored) at a location other than the jig installation position of the analysis mechanism 2 in the automatic analyzer 1, such as outside the automatic analyzer 1. Hereinafter, in this embodiment, the light intensity measurement jig 212 will be described assuming it is installed at the jig installation position of the analysis mechanism 2.

Furthermore, in the analysis mechanism 2 according to this embodiment, the same number of photometric units as the reaction tubes 2011 that can be held in the reaction disk 201 are provided inside. These photometric units constitute the photometric section in this embodiment. Figures 3 and 4 are schematic diagrams showing examples of the configuration of these photometric units 213. Figure 3 is a schematic diagram showing an example of the positional relationship of each component when the photometric unit 213 is viewed from above the reaction disk 201. Figure 4 is a schematic diagram showing an example of the positional relationship of each component when the photometric unit 213 is viewed from the cross-sectional direction of the reaction disk 201.

The photometric unit 213 continuously measures the optical properties of the mixture of sample and reagent dispensed into the reaction tube 2011. In the analytical mechanism 2 according to this embodiment, multiple photometric units 213 are provided. For example, the number of photometric units 213 is equal to the number of reaction tubes that can be held by the reaction disk 201. That is, one photometric unit 213 is provided for each reaction tube held by the reaction disk 201. Since the configuration of each photometric unit 213 is similar, Figures 3 and 4 show a representative example of one photometric unit 213.

The photometric unit 213 shown in Figures 3 and 4 includes, for example, a light-emitting unit 2131 and photodetectors 2132 and 2133. For instance, the photometric unit 213 has the light-emitting unit 2131 on the annular center side of the reaction tube 2011, which is held annularly by the reaction disk 201. The light-emitting unit 2131 is positioned to irradiate light toward the outside of the ring in which the reaction tubes 2011 are arranged.

The light-emitting unit 2131 generates light of two different wavelengths. For example, the light-emitting unit 2131 generates a first light with a longer wavelength and a second light with a shorter wavelength. For example, the wavelength of the first light falls within the red wavelength range of 620 to 750 nm, and the wavelength of the second light falls within the violet to blue wavelength range of 380 to 495 nm. Note that the wavelengths of the first and second light may each fall within the red wavelength range of 620 to 750 nm. The light-emitting unit 2131 can be realized, for example, by a multi-wavelength LED capable of generating light of multiple wavelengths, two LEDs each generating light of a predetermined wavelength, and a light source unit that transmits light of a desired wavelength from a wide wavelength range using a filter.

The light-emitting unit 2131 generates first and second light according to the control of the control circuit 9. Specifically, for example, the light-emitting unit 2131 alternately generates first and second light at a predetermined cycle. At this time, the light-emitting unit 2131 alternately generates first and second light at a cycle of 0.05 seconds, which is half of the smallest measurement unit of solidification, for example, 0.1 seconds. The light emitted from the light-emitting unit 2131 is incident on the reaction tube 2011.

Furthermore, the light-emitting unit 2131 may be configured to generate light of one wavelength specified by the control circuit 9. Alternatively, the light-emitting unit 2131 may generate the first and second wavelengths of light simultaneously. However, in this case, filters for excluding unwanted wavelengths of light must be provided in the photodetectors 2132 and 2133.

The photodetector 2132 is positioned opposite the light-emitting unit 2131, with the reaction tube 2011 in between. Light emitted from the light-emitting unit 2131 enters the reaction tube 2011 from the first side wall and exits from the second side wall opposite the first side wall. The photodetector 2132 detects the light emitted from the reaction tube 2011.

Specifically, for example, the photodetector 2132 detects light transmitted through the mixture of standard solution and reagent in the reaction tube 2011. The photodetector 2132 samples the detected light at predetermined time intervals, for example, 0.1-second intervals, and generates standard data represented by transmitted light intensity or absorbance. The predetermined time interval is synchronized, for example, with the frequency of the first light emission. The photodetector 2132 may also be configured to detect only light with a wavelength corresponding to the wavelength of the first light. Furthermore, the photodetector 2132 detects light transmitted through the mixture of blood sample and reagent in the reaction tube 2011. The photodetector 2132 samples the detected light at predetermined time intervals and generates test data represented by transmitted light intensity or absorbance. The photodetector 2132 outputs the generated standard data and test data to the analysis circuit 3.

The photodetector 2133 is positioned so that the light irradiation axis of the light-emitting unit 2131 and the light-receiving axis of the photodetector 2133 intersect at approximately 90 degrees within the reaction tube 2011. Light emitted from the light-emitting unit 2131 enters the reaction tube 2011 from the first side wall, is scattered by particles in the mixed liquid, and then exits from the third side wall, which is adjacent to the first side wall at a 90-degree angle. The photodetector 2133 detects the light emitted from the reaction tube 2011. The photodetector 2133 is, for example, an example of a scattered light receiving unit.

Specifically, for example, the photodetector 2133 detects light scattered by the mixture of standard solution and reagent in the reaction tube 2011. The photodetector 2133 samples the detected light at predetermined time intervals, for example, 0.1-second intervals, and generates standard data represented by scattered light intensity, etc. The predetermined time interval is synchronized, for example, with the frequency of the second light emission. The photodetector 2133 may also be configured to detect only light with a wavelength corresponding to the wavelength of the second light. Furthermore, the photodetector 2133 detects light scattered by the mixture of blood sample and reagent in the reaction tube 2011. The photodetector 2133 samples the detected light at predetermined time intervals and generates test data represented by scattered light intensity, etc. The photodetector 2133 outputs the generated standard data and test data to the analysis circuit 3.

Furthermore, the photodetectors 2132 and 2133 may output the detected light intensity as a detection signal to the analysis circuit 3. In this case, the analysis circuit 3 samples the detection signal at predetermined time intervals, for example, 0.1-second intervals, to generate standard data and test data.

Figure 5 is a schematic diagram showing another configuration example of the photometric unit 213 according to this embodiment. Similar to Figure 3, Figure 5 shows an example of the positional relationship of each component when the photometric unit 213 is viewed from above the reaction disk 201. The photometric unit 213 shown in Figure 5 has two LEDs 51 and 52 as the light-emitting section 2131. In the example shown in Figure 5, the light irradiation axis of LED 52 is tilted by a predetermined angle relative to the light irradiation axis of LED 51.

The photodetector 2132 is positioned opposite the LED 51, across the reaction tube 2011, similar to the examples in Figures 3 and 4. On the other hand, the photodetector 2133 is positioned so that the light irradiation axis of the LED 52 and the light receiving axis of the photodetector 2133 intersect at approximately 90 degrees within the reaction tube 2011.

The control circuit 9 shown in Figure 1 implements the functions corresponding to the control program stored in the memory circuit 8 by executing the program. For example, the control circuit 9 has a system control function 91, a first control function 92, a measurement function 93, and a first reporting function 94 by executing the control program. In this embodiment, the case in which the system control function 91, the first control function 92, the measurement function 93, and the first reporting function 94 are implemented by a single processor is described, but this is not the only case. For example, the control circuit may be configured by combining multiple independent processors, and each processor may implement these various functions by executing a control program.

The system control function 91 is a function that comprehensively controls each part of the automatic analyzer 1 based on the input information received from the input interface 5. For example, in the system control function 91, the control circuit 9 controls the drive mechanism 4 and the analysis mechanism 2, thereby controlling the sample dispensing arm 206 and the reagent dispensing arm 208 to dispense samples and reagents into the reaction tube 2011, and also controls the analysis circuit 3 to perform analysis according to the test items.

The first control function 92 controls the reaction tube transport arm 210 and the imaging unit 2103 provided on the reaction tube transport arm 210 by controlling the analysis mechanism 2 and the drive mechanism 4. Specifically, the first control function 92 controls the reaction tube transport arm 210 to transport the reaction tube 2011 from the reaction tube supply unit 211 to the reaction disk 201, and controls the imaging unit 2103 provided on the reaction tube transport arm 210 to image the reaction tube 2011. Furthermore, the first control function 92 controls the reaction tube transport arm 210 to transport the light intensity measuring jig 212 to the reaction disk 201.

The measurement function 93 is a function that measures the light intensity of the light-emitting unit 2131 and the optical axis height of the light-emitting unit 2131. Specifically, the measurement function 93 controls the photometric unit 213 and other components to measure the light intensity of the light-emitting unit 2131 received by the imaging unit 2103 via the light intensity measurement jig 212, and the optical axis height of the light-emitting unit 2131, which is the height from the bottom surface of the light intensity measurement jig 212 to the optical axis of the light-emitting unit 2131.

The first reporting function 94 is a function that reports to the user the measurement results of the light intensity of the light-emitting unit 2131 and the measurement results of the optical axis height of the light-emitting unit 2131. Specifically, the first reporting function 94 reports to the user, via the output interface 6, at least one of the measurement results of the light intensity of the light-emitting unit 2131 measured by the measurement function 93, and the measurement results of the optical axis height of the light-emitting unit 2131 measured by the measurement function 93.

Furthermore, the system control function 91, first control function 92, measurement function 93, and first reporting function 94 shown in Figure 1 constitute the system control unit, first control unit, measurement unit, and first reporting unit, respectively, in this embodiment.

Figure 6 is a flowchart illustrating the measurement process performed by the automated analyzer 1 according to this embodiment. This measurement process measures the light intensity and optical axis height of the light-emitting unit 2131, and reports the results of these measurements to the user. For example, this measurement process is performed at a user-specified time, such as before using the device every morning or once a week.

As shown in Figure 6, first, the automatic analyzer 1 moves the reaction tube holder 2101 on the reaction tube transport arm 210 to the jig installation position (step S11). This process of moving the reaction tube holder 2101 to the jig installation position is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to move the reaction tube holder 2101 to the jig installation position.

Furthermore, if the light intensity measurement jig 212 is installed (stored) outside the automatic analyzer 1, or in a location other than the jig installation location of the analysis mechanism 2 in the automatic analyzer 1, the user may install the light intensity measurement jig 212 at the jig installation location and have it held by the reaction tube holder 2101, or the user may carry the light intensity measurement jig 212 from the installation location to the reaction tube holder 2101 and have the user hold the light intensity measurement jig 212 in the reaction tube holder 2101. If the user carries the light intensity measurement jig 212 from the installation location to the reaction tube holder 2101, the reaction tube transport arm 210 does not need to move. In other words, if the light intensity measurement jig 212 is installed (stored) outside the automatic analyzer 1, or in a location other than the jig installation location of the analysis mechanism 2 in the automatic analyzer 1, step S11 may be omitted.

Next, as shown in Figure 6, the automatic analyzer 1 holds the light intensity measuring jig 212 (step S13). This process of holding the light intensity measuring jig 212 is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to hold the light intensity measuring jig 212 at the jig installation position using the reaction tube holding unit 2101.

Next, as shown in Figure 6, the automatic analyzer 1 places the light intensity measuring jig 212 onto the reaction disk 201 (step S15). This placement process onto the reaction disk 201 is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to place the light intensity measuring jig 212 at the reaction tube placement position on the reaction disk 201.

Next, as shown in Figure 6, the automatic analyzer 1 causes the light-emitting unit 2131 to emit light (step S17). This process of causing the light-emitting unit 2131 to emit light is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 causes the light-emitting unit 2131 on which the light intensity measuring jig 212 is installed to emit light. Note that in step S17, the automatic analyzer 1 may also cause the light-emitting unit 2131 on which the light intensity measuring jig 212 is installed to emit light, as well as the light-emitting unit 2131 on which the light intensity measuring jig 212 is not installed.

Next, as shown in Figure 6, the automatic analyzer 1 measures the light intensity of the light-emitting unit 2131 (step S19). This process of measuring the light intensity of the light-emitting unit 2131 is implemented by the measurement function 93 in the control circuit 9. Specifically, the automatic analyzer 1 measures the light intensity of the light-emitting unit 2131 by receiving the light emitted by the light-emitting unit 2131 via the mirror 2121 of the light intensity measurement jig 212, which is then received by the imaging unit 2103 of the reaction tube transport arm 210.

Next, as shown in Figure 6, the automatic analyzer 1 measures the optical axis height of the light-emitting unit 2131 (step S21). This measurement of the optical axis height of the light-emitting unit 2131 is performed by the measurement function 93 in the control circuit 9. Specifically, the automatic analyzer 1 measures the optical axis height of the light-emitting unit 2131 based on the light-receiving position, which is the position within the imaging unit 2103 where the light emitted from the light-emitting unit 2131 is received by the imaging unit 2103.

Figure 7 is a schematic diagram illustrating an example of the relationship between the light-receiving position of the imaging unit 2103 and the optical axis height of the light-emitting unit 2131 in the automatic analyzer 1 according to this embodiment. As shown in Figure 7, the light intensity measuring jig 212, installed at the reaction tube installation position of the reaction disk 201, reflects the light emitted from the light-emitting unit 2131 using the mirror 2121, causing the imaging unit 2103 to receive the light emitted from the light-emitting unit 2131. At this time, as shown in Figure 7(a), if the position where the light-emitting unit 2131 irradiates the mirror 2121 is below the height of the mirror 2121, i.e., the optical axis height H is low, the light emitted from the light-emitting unit 2131 will irradiate a position to the left of the center of the imaging unit 2103, i.e., a position within the imaging unit 2103 close to the light-emitting unit 2131 (proximal).

Furthermore, as shown in Figure 7(b), if the position where the light-emitting unit 2131 irradiates the mirror 2121 is near the center in the height direction of the mirror 2121, the light emitted from the light-emitting unit 2131 will irradiate the center position of the imaging unit 2103. Moreover, as shown in Figure 7(c), if the position where the light-emitting unit 2131 irradiates the mirror 2121 is above the height direction of the mirror 2121, i.e., when the optical axis height H is high, the light emitted from the light-emitting unit 2131 will irradiate a position to the right of the center of the imaging unit 2103, i.e., a position within the imaging unit 2103 that is far from the light-emitting unit 2131 (distal). In other words, since there is a certain relationship between the light-receiving position of the imaging unit 2103 and the optical axis height H of the light-emitting unit 2131, the automatic analyzer 1 can measure the optical axis height H of the light-emitting unit 2131 based on the light-receiving position of the imaging unit 2103, as shown in Figure 7. In the example shown in Figure 7, the reaction tube holder 2101 does not hold the light intensity measurement jig 212. However, the automatic analyzer 1 may measure the optical axis height H while holding the light intensity measurement jig 212.

Next, as shown in Figure 6, the automatic analyzer 1 determines whether the light intensity is outside a predetermined range (step S23). This determination of whether the light intensity is outside a predetermined range is achieved by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 determines whether the measurement result of the light intensity measured in step S19 is outside a predetermined range.

Then, if it is determined that the light intensity is not outside the predetermined range (Step S23: No), the automatic analyzer 1 reports the light intensity measurement result and that the light intensity measurement result is not outside the predetermined range (Step S25). This reporting process is realized by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 reports to the user via the output interface 6 that the light intensity measurement result of the light-emitting unit 2131 measured in Step S19 and the light intensity measurement result of the light-emitting unit 2131 determined in Step S23 are not outside the predetermined range, that is, the light intensity measurement result of the light-emitting unit 2131 determined in Step S23 is within the predetermined range.

On the other hand, if the light intensity is determined to be outside a predetermined range (step S23: Yes), the automatic analyzer 1 automatically adjusts the light intensity (step S27). This automatic adjustment of light intensity is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1, for example, automatically adjusts the gain of the light intensity of the light-emitting unit 2131 and measures the light intensity of the light-emitting unit 2131 after the automatic adjustment.

Next, as shown in Figure 6, the automatic analyzer 1 determines whether the light intensity after automatic adjustment is outside a predetermined range (step S29). This process of determining whether it is outside the predetermined range is realized by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 determines whether the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment, measured in step S27, is outside a predetermined range.

Then, if the light intensity after automatic adjustment in step S27 is not outside the predetermined range (step S29: No), the automatic analyzer 1 reports the measurement result of the light intensity after automatic adjustment and that the measurement result of the light intensity after automatic adjustment is not outside the predetermined range (step S31). This reporting process is realized by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 reports to the user via the output interface 6 that the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment measured in step S27 and the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment determined in step S29 are not outside the predetermined range, that is, the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment determined in step S29 is within the predetermined range.

On the other hand, if the light intensity after automatic adjustment is outside a predetermined range (step S29: Yes), the automatic analyzer 1 reports the measurement result of the light intensity after automatic adjustment and that the measurement result of the light intensity after automatic adjustment is outside a predetermined range (step S33). This reporting process is realized by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 reports to the user via the output interface 6 that the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment, measured in step S27, and the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment, determined in step S39, are outside a predetermined range. Furthermore, when the automatic analyzer 1 reports to the user that the measurement result of the light intensity of the light-emitting unit 2131 is outside a predetermined range, it may display a setting screen on the display circuit of the output interface 6 that allows the user to set whether or not to use the reaction tube installation position of the reaction disk 201 in which the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment is outside the predetermined range. Alternatively, the automatic analyzer 1 may be configured to automatically not use the reaction tube installation position of the reaction disk 201 in which the measurement result of the light intensity of the light-emitting unit 2131 after automatic adjustment is outside the predetermined range.

Next, as shown in Figure 6, the automatic analyzer 1 determines whether the optical axis height H is outside a predetermined range (step S35). This determination of whether it is outside the predetermined range is achieved by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 determines whether the measurement result of the optical axis height H of the light-emitting unit 2131, measured in step S21, is outside the predetermined range.

Then, if the optical axis height H is not outside the predetermined range (step S35: No), the automatic analyzer 1 reports the measurement result of the optical axis height H and that the measurement result of the optical axis height H is not outside the predetermined range (step S37). This reporting process is realized by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 reports to the user via the output interface 6 that the measurement result of the optical axis height H of the light-emitting unit 2131 measured in step S21 and the measurement result of the optical axis height H of the light-emitting unit 2131 determined in step S35 are not outside the predetermined range, that is, the measurement result of the optical axis height H of the light-emitting unit 2131 determined in step S35 is within the predetermined range.

On the other hand, if the optical axis height H is outside a predetermined range (step S35: Yes), the automatic analyzer 1 reports the measurement result of the optical axis height H of the light-emitting unit 2131 and that the measurement result of the optical axis height H of the light-emitting unit 2131 is outside a predetermined range (step S39). This reporting process to the user is realized by the first reporting function 94 in the control circuit 9. Specifically, the automatic analyzer 1 reports to the user via the output interface 6 that the measurement result of the optical axis height H of the light-emitting unit 2131 measured in step S21 and the measurement result of the optical axis height H of the light-emitting unit 2131 determined in step S35 are outside a predetermined range. Furthermore, when the automatic analyzer 1 reports to the user that the measurement result of the optical axis height H of the light-emitting unit 2131 is outside a predetermined range, it may display a setting screen on the display circuit of the output interface 6 that allows the user to set whether or not to use the reaction tube installation position of the reaction disk 201 where the optical axis height H of the light-emitting unit 2131 is outside the predetermined range. Alternatively, the automatic analyzer 1 may be configured to automatically not use the reaction tube installation position of the reaction disk 201 where the optical axis height H of the light-emitting unit 2131 is outside the predetermined range.

Next, as shown in Figure 6, the automatic analyzer 1 determines whether measurement of the other light-emitting units 2131 is necessary (step S41). This process of determining whether measurement of the other light-emitting units 2131 is necessary is implemented by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 determines whether measurement of the other light-emitting units 2131 is necessary based on whether the measurement of the other light-emitting units 2131 has been completed.

Then, if measurement of other light-emitting units 2131 is required (step S41: Yes), the automatic analyzer 1 holds the light intensity measuring jig 212 (step S43). This process of holding the light intensity measuring jig 212 is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to hold the light intensity measuring jig 212, which is installed at the reaction tube installation position on the reaction disk 201, using the reaction tube holding unit 2101.

Next, as shown in Figure 6, the automatic analyzer 1 places the light intensity measuring jig 212 on the reaction disk 201 (step S45). This placement on the reaction disk 201 is achieved by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to transport the light intensity measuring jig 212 in order to measure the other light-emitting units 2131, and places the light intensity measuring jig 212 at the next reaction tube placement position on the reaction disk 201. Then, it returns to step S17 and repeats the process from step S17.

On the other hand, if it is determined that no other light-emitting units 2131 need to be measured (step S41: No), the automatic analyzer 1 terminates the measurement process according to this embodiment by executing step S41.

As described above, according to the automatic analyzer 1 of this embodiment, the reaction tube transport arm 210 is controlled to transport one light intensity measuring jig 212 to the reaction disk 201, and the light intensity and optical axis height H of the multiple light-emitting units 2131 provided on the reaction disk 201 are measured using one light intensity measuring jig 212. Therefore, the measurement accuracy of the automatic analyzer 1 can be improved. In other words, by using one light intensity measuring jig 212, the automatic analyzer 1 is not affected by individual differences in the light intensity measuring jigs, thus preventing variations in the light intensity of the adjusted light-emitting units 2131 and reducing the possibility of variations in the measurement results of the light intensity of the multiple light-emitting units 2131 and the optical axis height H of the light-emitting units 2131.

[Modification 1 of the First Embodiment]
In the automatic analyzer 1 according to the first embodiment described above, the optical axis height H of the light-emitting unit 2131 is measured based on the light-receiving position, which is the position where the imaging unit 2103 receives light emitted from the light-emitting unit 2131. However, it is also possible to measure the optical axis height H of the light-emitting unit 2131 based on the amount of descent of the light intensity measuring jig 212 when the imaging unit 2103 receives light emitted from the light-emitting unit 2131 at a predetermined position within the imaging unit 2103. Hereinafter, a modification in which this modification is applied to the first embodiment will be referred to as Modification 1, and the parts that differ from the first embodiment described above will be explained.

The functional configuration of the automatic analyzer 1 according to Modification 1 of the First Embodiment is equivalent to that of Figure 1, so its explanation is omitted. Furthermore, the configuration of the analysis mechanism 2 in the automatic analyzer 1 according to Modification 1 of the First Embodiment is equivalent to that of Figure 2, so its explanation is omitted. Finally, the configuration of the photometric unit 213 in the automatic analyzer 1 according to Modification 1 of the First Embodiment is equivalent to that of Figures 3 and 4, so its explanation is omitted.

Figures 8 and 9 are flowcharts illustrating the measurement process performed by the automatic analyzer 1 according to Modification 1 of the First Embodiment, and correspond to Figure 6 in the First Embodiment described above. Note that the processes in steps S11 and S13 shown in Figure 8 are equivalent to those in Figure 6 of the First Embodiment described above, and therefore their explanation is omitted.

Next, as shown in Figure 8, the automatic analyzer 1 transports the light intensity measuring jig 212 above the reaction disk 201 (step S51). This transport above the reaction disk 201 is achieved by the first control function 92 of the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to transport the light intensity measuring jig 212 above the reaction tube installation position on the reaction disk 201. Note that the process in step S17 shown in Figure 8 is equivalent to that in Figure 6 of the first embodiment described above, so its explanation is omitted.

Next, as shown in Figure 8, the automatic analyzer 1 lowers the light intensity measuring jig 212 (step S53). This process of lowering the light intensity measuring jig 212 is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to lower the light intensity measuring jig 212 at the reaction tube installation position on the reaction disk 201.

Next, as shown in Figure 8, the automatic analyzer 1 determines whether or not light was received at a predetermined position within the imaging unit 2103 (step S55). This process of determining whether or not light was received at a predetermined position within the imaging unit 2103 is implemented by the first control function in the control circuit 9. Specifically, the automatic analyzer 1 determines whether or not the imaging unit 2103 received light emitted from the light-emitting unit 2131 at a predetermined position within the imaging unit 2103.

Then, as shown in Figure 8, if the imaging unit 2103 has not received the light emitted from the light-emitting unit 2131 at a predetermined position within the imaging unit 2103 (step S55: No), the process returns to step S53 described above, and the process from step S35 is repeated while waiting. That is, the automatic analyzer 1 controls the reaction tube transport arm 210 to lower the light intensity measuring jig 212, and waits until the imaging unit 2103 receives the light emitted from the light-emitting unit 2131 at a predetermined position within the imaging unit 2103.

On the other hand, in step S55, if the imaging unit 2103 receives light emitted from the light-emitting unit 2131 at a predetermined position within the imaging unit 2103 (step S55: Yes), the automatic analyzer 1 acquires the amount of descent of the light intensity measuring jig 212 (step S57). This acquisition of the descent amount is realized by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 acquires the amount of descent of the light intensity measuring jig 212 when the imaging unit 2103 receives light emitted from the light-emitting unit 2131 at a predetermined position within the imaging unit 2103. Note that step S19 after step S39 is the same as in the first embodiment described above, so its explanation is omitted.

Next, as shown in Figure 8, the automatic analyzer 1 measures the optical axis height H (step S59). This measurement of the optical axis height H is performed by the measurement function 93 in the control circuit 9. Specifically, the automatic analyzer 1 measures the optical axis height H based on the amount of descent of the light intensity measuring jig 212 acquired in step S57.

Figure 10 is a schematic diagram illustrating an example of the relationship between the descent amount of the light intensity measuring jig 212 and the optical axis height of the light-emitting unit 2131 in an automatic analyzer 1 according to a modified example 1 of the first embodiment. In the example shown in Figure 10, the predetermined position P within the imaging unit 2103 is near the center of the imaging unit 2103. As shown in Figure 10(a), the automatic analyzer 1 controls the reaction tube transport arm 210 to lower the light intensity measuring jig 212 to the reaction disk 201 at the reaction tube installation position, thereby installing it on the reaction disk 201. In the example shown in Figure 10(a), the imaging unit 2103 does not receive light emitted from the light-emitting unit 2131. That is, the light emitted from the light-emitting unit 2131 does not illuminate the mirror 2121 of the light intensity measuring jig 212.

Next, as shown in Figure 10(b), the automatic analyzer 1 controls the reaction tube transport arm 210 to further lower the light intensity measuring jig 212 at the reaction tube installation position of the reaction disk 201. In the example shown in Figure 10(b), the light emitted from the light-emitting unit 2131 is irradiated onto the mirror 2121 of the light intensity measuring jig 212, and the mirror 2121 reflects the light emitted from the light-emitting unit 2131 to the imaging unit 2103. The imaging unit 2103 receives the light emitted from the light-emitting unit 2131 via the mirror 2121. However, since the position where the imaging unit 2103 receives the light emitted from the light-emitting unit 2131 is not the predetermined position P within the imaging unit 2103, the automatic analyzer 1 further lowers the light intensity measuring jig 212.

Next, as shown in Figure 10(c), the automatic analyzer 1 further lowers the light intensity measuring jig 212 so that the light emitted from the light-emitting unit 2131 is received at a predetermined position P within the imaging unit 2103 via the mirror 2121 of the light intensity measuring jig 212. At this time, the automatic analyzer 1 controls the reaction tube transport arm 210 at the reaction tube installation position on the reaction disk 201 to obtain the amount of descent of the light intensity measuring jig 212. Based on this amount of descent, the optical axis height H of the light-emitting unit 2131 is measured. Note that when the imaging unit 2103 receives the light emitted from the light-emitting unit 2131 at a predetermined position P within the imaging unit 2103, the light intensity measuring jig 212 may be installed on the reaction disk 201, or, as shown in Figure 10(c), the light intensity measuring jig 212 may not be installed on the reaction disk 201.

The processes from step S23 to step S43 shown in Figure 9, which follow step S59, are equivalent to those in Figure 6 of the first embodiment described above, and therefore their explanation is omitted.

Next, as shown in Figure 9, the automatic analyzer 1 transports the light intensity measuring jig 212 above the reaction disk 201. This transport above the reaction disk 201 is achieved by the first control function 92 in the control circuit 9. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to transport the light intensity measuring jig 212 and place it at the reaction tube installation position of the next light-emitting unit 2131. Then, the process returns to step S17 and repeats the process from step S17.

On the other hand, if it is determined that no other light-emitting units 2131 need to be measured (step S41: No), the automatic analyzer 1 terminates the measurement process according to the modified example 1 of this embodiment by executing step S41.

As described above, in the automatic analyzer 1 according to Modification 1 of the first embodiment, similar to the first embodiment, the reaction tube transport arm 210 is controlled to transport one light intensity measuring jig 212 to the reaction disk 201, and the light intensity and optical axis height H of the multiple light-emitting units 2131 provided on the reaction disk 201 are measured using one light intensity measuring jig 212. Therefore, the measurement accuracy of the automatic analyzer 1 can be improved. In other words, by using one light intensity measuring jig 212, the automatic analyzer 1 is not affected by individual differences in the light intensity measuring jig 212, thus preventing variations in the adjusted light intensity of the light-emitting units 2131 and reducing the possibility of variations in the measurement results of the light intensity of the light-emitting units 2131 and the optical axis height H of the light-emitting units 2131.

[Modification 2 of the first embodiment]
In the first embodiment described above and the modification 1 of the first embodiment described above, the automatic analyzer 1 measures both the light intensity of the light-emitting unit 2131 and the optical axis height H of the light-emitting unit 2131 and reports the measurement results to the user. However, the automatic analyzer 1 according to the modification 2 of the first embodiment may measure either the light intensity of the light-emitting unit 2131 or the optical axis height H of the light-emitting unit 2131 and report it to the user.

[Second Embodiment]
In the first embodiment described above, the automatic analyzer 1 controls the reaction tube transport arm 210 to transport the light intensity measuring jig 212 to the reaction disk 201, and the imaging unit 2103 measures the light intensity of the light-emitting unit 2131 and the optical axis height H of the light-emitting unit 2131. However, the imaging unit 2103 can be used for other purposes. Therefore, the automatic analyzer 1 according to the second embodiment controls the reaction tube transport arm 210 to hold the reaction tubes 2011 supplied by the reaction tube supply unit, and determines whether the reaction tubes 2011 held by the reaction tube transport arm 210 are usable for inspection based on the image captured by the imaging unit 2103, and discards any unusable reaction tubes 2011. The following describes the parts that differ from the first embodiment described above.

Figure 11 is a block diagram showing an example of the functional configuration of the automatic analysis apparatus 1 according to the second embodiment, and corresponds to Figure 1 in the first embodiment described above. As shown in Figure 11, the automatic analysis apparatus 1 according to this embodiment comprises an analysis mechanism 2A, an analysis circuit 3, a drive mechanism 4, an input interface 5, an output interface 6, a communication interface 7, a memory circuit 8, and a control circuit 9A. Note that the configurations of the analysis circuit 3, drive mechanism 4, input interface 5, output interface 6, communication interface 7, and memory circuit 8 in the second embodiment are equivalent to those in the first embodiment, so their explanation is omitted.

Figure 12 shows an example of the configuration of the analysis mechanism 2A in the automated analyzer 1 shown in Figure 11. As shown in Figure 12, the analysis mechanism 2A according to this embodiment comprises a reaction disk 201, a constant temperature unit 202, a rack sampler 203, a reagent storage unit 204, a sample dispensing arm 206, a sample dispensing probe 207, a reagent dispensing arm 208, and a reagent dispensing probe 209. Note that the configurations of the reaction disk 201, constant temperature unit 202, rack sampler 203, reagent storage unit 204, sample dispensing arm 206, sample dispensing probe 207, reagent dispensing arm 208, and reagent dispensing probe 209 in the second embodiment are equivalent to those in the first embodiment, and therefore their description is omitted.

Furthermore, the analysis mechanism 2A according to this embodiment includes a reaction tube transport arm 210, a reaction tube supply unit 211A, and a waste box 214. Although the light intensity measuring jig 212 is omitted from Figure 12, the analysis mechanism 2A according to the second embodiment may include a light intensity measuring jig 212, similar to the first embodiment described above. Also, the configuration of the reaction tube transport arm 210 is the same as in the first embodiment, so its description is omitted.

The reaction tube supply unit 211A supplies empty reaction tubes 2011. The reaction tube supply unit 211A is located near the outer circumference of the reaction disk 201. In this embodiment, the reaction tube supply unit 211A is configured to include, for example, a reaction tube housing unit 2111, a reaction tube supply rail 2112, and a light source unit 2113. The light source unit 2113 irradiates light onto the reaction tubes 2011 to check for foreign matter, cracks, chips, etc. Therefore, the light source unit 2113 is positioned to irradiate light onto the reaction tubes 2011 supplied to the reaction tube supply position. In the example shown in Figure 12, the light source unit 2113 is located directly below the reaction tube supply position on the reaction tube supply rail 2112 and irradiates light onto the reaction tubes 2011 from the bottom surface direction. The configuration of the reaction tube housing section 2111 and the reaction tube supply rail 2112 is the same as in the first embodiment, therefore, a detailed explanation is omitted.

Furthermore, in the reaction tube supply unit 211A according to this embodiment, the light source unit 2113 is positioned to irradiate the reaction tube 2011 supplied to the reaction tube supply position with light. However, the position of the light source unit 2113 is not limited to this. That is, the position of the light source unit 2113 is arbitrary; for example, the light source unit 2113 may be installed at a predetermined position on the rotating trajectory, which is the transport path of the reaction tube transport arm 210.

Furthermore, in the example shown in Figure 12, the light source unit 2113 is configured to irradiate the reaction tube 2011 from the bottom. However, the direction in which the light source unit 2113 irradiates the reaction tube 2011 is not limited to the bottom. That is, the direction in which the light source unit 2113 irradiates the reaction tube 2011 is arbitrary. For example, the light source unit 2113 may irradiate the reaction tube 2011 from the side, or it may irradiate the reaction tube 2011 from the top.

The waste box 214 is a box for storing discarded reaction tubes 2011, such as used reaction tubes 2011 containing a mixture of sample and reagent, or reaction tubes 2011 deemed unusable. The waste box 214 is located near the outer circumference of the reaction disk 201. The discarded reaction tubes 2011 are transported to the reaction tube disposal position in the waste box 214 by the reaction tube transport arm 210, etc. The reaction tube disposal position is, for example, the position where the opening of the waste box 214 intersects with the rotational trajectory, which is the transport path of the reaction tube 2011 held by the reaction tube holding section 2101 of the reaction tube transport arm 210. Note that the waste box 214 constitutes the reaction tube disposal section in this embodiment.

Furthermore, in the analysis mechanism 2A according to this embodiment, the same number of photometric units 213 as the number of reaction tubes 2011 that can be held in the reaction disk 201 are provided inside. These photometric units 213 constitute the photometric section in this embodiment. The configuration of these photometric units 213 is the same as that of the first embodiment, and therefore, a detailed explanation is omitted.

The control circuit 9A shown in Figure 11 realizes the functions corresponding to the control program stored in the memory circuit 8 by executing the program. For example, the control circuit 9A has a system control function 91, a first control function 92, a measurement function 93, a first reporting function 94, a first determination function 95, and a second reporting function 96 by executing the control program. In this embodiment, the case in which the system control function 91, the first control function 92, the measurement function 93, the first reporting function 94, the first determination function 95, and the second reporting function 96 are realized by a single processor is described, but it is not limited to this. For example, the control circuit may be configured by combining multiple independent processors, and these various functions may be realized by each processor executing a control program. Furthermore, the functions of the system control function 91, the first control function 92, the measurement function 93, and the first reporting function 94 in this embodiment are equivalent to the functions of the system control function 91, the first control function 92, the measurement function 93, and the first reporting function 94 shown in Figure 1, so their description is omitted.

The first determination function 95 analyzes the image of the reaction tube 2011 captured by the imaging unit 2103 controlled by the first control function 92, and determines whether the reaction tube 2011 is usable or not. Specifically, the first control function 92 analyzes the image of the reaction tube 2011 captured by the imaging unit 2103 to determine whether there are any foreign objects, cracks, chips, etc. in the reaction tube 2011, thereby determining whether the reaction tube 2011 is usable or not.

The second reporting function 96 informs the user to discard the reaction tube 2011 when the first determination function 95 determines that the reaction tube 2011 is unusable. Specifically, when the first determination function 95 determines that the reaction tube 2011 is unusable, the second reporting function 96 informs the user via the output interface 6 that the reaction tube 2011 is unusable and therefore should be discarded.

Furthermore, the system control function 91, first control function 92, measurement function 93, first reporting function 94, first determination function 95, and second reporting function 96 shown in Figure 11 constitute the system control unit, first control unit, measurement unit, first reporting unit, first determination unit, and second reporting unit, respectively, in this embodiment.

Figure 13 is a flowchart illustrating the reaction tube imaging process performed by the automated analyzer 1 according to this embodiment. This reaction tube imaging process involves imaging the reaction tube 2011, analyzing the captured images, reporting the results to the user, and discarding the reaction tube 2011 if it is unusable. For example, this reaction tube imaging process is executed at the time the reaction tube transport arm 210 transports the reaction tube 2011 supplied to the reaction tube supply unit 211A.

As shown in Figure 13, first, the automatic analyzer 1 moves the reaction tube transport arm 210 to the reaction tube supply unit 211A (step S71). This movement to the reaction tube supply unit 211A is realized by the first control function 92 in the control circuit 9A. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to move the reaction tube holding portion 2101 of the reaction tube transport arm 210 to the reaction tube supply position in the reaction tube supply unit 211A.

Next, as shown in Figure 13, the automatic analyzer 1 holds the reaction tube 2011 (step S73). This process of holding the reaction tube 2011 is realized by the first control function 92 in the control circuit 9A. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to hold the reaction tube 2011 supplied to the reaction tube supply position using the reaction tube holding section 2101 of the reaction tube transport arm 210.

Next, as shown in Figure 13, the automatic analyzer 1 causes the light source unit 2113 to emit light (step S75). This process of causing the light source unit 2113 to emit light is realized by the first control function 92 in the control circuit 9A.

Next, as shown in Figure 13, the automatic analyzer 1 images the reaction tube 2011 (step S77). This imaging of the reaction tube 2011 is realized by the first control function 92 in the control circuit 9A. Specifically, the automatic analyzer 1 controls the imaging unit 2103 so that it images the reaction tube 2011 when the reaction tube transport arm 210 transports the reaction tube 2011. More specifically, at the reaction tube supply position where the light source unit 2113 is located, the first control function 92 irradiates the reaction tube 2011, held by the reaction tube transport arm 210, with light from the light source unit 2113, and the imaging unit 2103 images the reaction tube 2011.

In step S77, the reaction tube 2011 was imaged by the imaging unit 2103 when it was held by the reaction tube transport arm 210 at the reaction tube supply position. However, the position at which the reaction tube 2011 is imaged is not limited to the reaction tube supply position. That is, the position at which the reaction tube 2011 is imaged is arbitrary. For example, the position at which the reaction tube 2011 is imaged may be above the light source unit 2113, which is positioned at a predetermined location on the rotational trajectory of the reaction tube transport arm 210, or it may be imaged at a position where it is not illuminated by light from the light source unit 2113.

Next, as shown in Figure 13, the automated analyzer 1 analyzes the image of the reaction tube 2011 (step S79). This image analysis process is implemented by the first determination function 95 in the control circuit 9A. Specifically, the automated analyzer 1 analyzes the image of the reaction tube 2011 captured in step S77 to determine if there is any damage such as cracks or chips.

Next, as shown in Figure 13, the automated analyzer 1 determines whether the reaction tube 2011, imaged in step S77, is usable (step S81). This determination of whether the reaction tube 2011 is usable is performed by the first determination function 95 in the control circuit 9. Specifically, the automated analyzer 1 determines whether the reaction tube 2011 is usable based on the analysis results in step S79 of the image of the reaction tube 2011 captured in step S77.

Then, in step S81, if it is determined that the reaction tube 2011, which was imaged in step S77, is usable (step S81: Yes), the automatic analyzer 1 transports the reaction tube 2011 to the reaction disk 201 (step S83). This transport of the reaction tube 2011 is realized by the first control function 92 of the control circuit 9A. More specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to transport the reaction tube 2011, which was held in step S73, to the reaction disk 201.

Next, as shown in Figure 13, the automatic analyzer 1 places the reaction tube 2011 on the reaction disk 201 (step S85). This placement process on the reaction disk 201 is achieved by the first control function 92 in the control circuit 9A. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to place the reaction tube 2011 at the reaction tube placement position on the reaction disk 201.

On the other hand, if, in step S81, it is determined that the reaction tube 2011, as imaged in step S77, is unusable (step S81: No), the automatic analyzer 1 reports to the user that the reaction tube 2011 should be discarded (step S87). This reporting process to the user is implemented by the second reporting function 96 in the control circuit 9A. Specifically, the automatic analyzer 1 reports to the user via the output interface 6 that the reaction tube 2011, as imaged in step S77, should be discarded.

Figure 14 is a schematic diagram showing an example of a case in the automated analyzer 1 according to this embodiment in which the reaction tube 2011 is determined to be unusable. In the example shown in Figure 14, the reaction tube 2011 is held by the reaction tube holding part 2101 of the reaction tube transport arm 210, and light irradiated from the light source unit 2113 is irradiated from the bottom surface of the reaction tube 2011. The example shown in Figure 14(a) shows a case in which foreign matter FM is mixed into the reaction tube 2011. This foreign matter FM is, for example, dust, dirt, etc. When foreign matter FM is mixed into the reaction tube 2011 in this way, the reaction tube 2011 is determined to be unusable. Furthermore, the example shown in Figure 14(b) shows a case in which the reaction tube 2011 has damage CR such as cracks or chips. When damage CR occurs in the reaction tube 2011 in this way, the reaction tube 2011 is determined to be unusable.

Next, as shown in Figure 13, the automatic analyzer 1 transports the reaction tube 2011 to the reaction tube disposal location (step S89). This transport of the reaction tube to the disposal location is achieved by the first control function 92 in the control circuit 9A. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to transport the reaction tube 2011, which was determined to be unusable in step S81, to the reaction tube disposal location in the waste box 214.

Next, as shown in Figure 13, the automatic analyzer 1 discards the reaction tube 2011 (step S91). This disposal of the reaction tube 2011 is achieved by the first control function 92 in the control circuit 9A. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to store the reaction tube 2011, held in the reaction tube holding unit 2101, into the disposal box 214, thereby discarding the reaction tube 2011.

By executing step S85 or step S91, the reaction tube imaging process according to this embodiment is terminated.

As described above, according to the automatic analyzer 1 of this embodiment, all reaction tubes 2011 supplied from the reaction tube supply unit 211A are imaged by the imaging unit 2103 before being placed on the reaction disk 201, and it is determined whether or not they are usable. Reaction tubes 2011 that are unusable are discarded without being placed on the reaction disk 201, thus improving the measurement accuracy of the automatic analyzer 1. Specifically, if dust is present in a reaction tube 2011, or if cracks or chips occur in the reaction tube 2011, the automatic analyzer 1 determines that the reaction tube 2011 is unusable and discards it without being used for inspection. Therefore, the possibility of obtaining incorrect measurement results due to the use of reaction tubes 2011 containing dust, chips, and/or cracks is reduced. This allows for improved measurement accuracy of the automatic analyzer 1.

[Third Embodiment]
The automated analyzer 1 according to the third embodiment controls a reaction tube transport arm 210 to transport a used reaction tube 2011 containing a mixture of sample and reagent (hereinafter referred to as "used reaction tube") to a reaction tube disposal position, images the used reaction tube 2011, and analyzes the image of the used reaction tube 2011 to determine whether or not there is an abnormality in the used reaction tube 2011, and reports to the user if there is an abnormality. The automated analyzer 1 according to this third embodiment can be implemented additionally to or independently of the automated analyzer 1 according to the first embodiment and/or the second embodiment described above. Hereinafter, the differences between this third embodiment and the first and second embodiments described above will be explained assuming that this third embodiment is implemented independently of the first and second embodiments described above.

Figure 15 is a block diagram showing an example of the functional configuration of the automatic analysis device 1 according to the third embodiment, and corresponds to Figure 1 in the first embodiment described above. As shown in Figure 15, the automatic analysis device 1 according to this embodiment comprises an analysis mechanism 2B, an analysis circuit 3, a drive mechanism 4, an input interface 5, an output interface 6, a communication interface 7, a memory circuit 8, and a control circuit 9B. Note that the configurations of the analysis circuit 3, drive mechanism 4, input interface 5, output interface 6, communication interface 7, and memory circuit 8 in the second embodiment are equivalent to those in the first embodiment, so their description is omitted.

Figure 16 shows an example of the configuration of the analysis mechanism 2B in the automated analyzer 1 shown in Figure 15. As shown in Figure 16, the analysis mechanism 2B according to this embodiment comprises a reaction disk 201, a constant temperature unit 202, a rack sampler 203, a reagent storage unit 204, a sample dispensing arm 206, a sample dispensing probe 207, a reagent dispensing arm 208, and a reagent dispensing probe 209. Note that the configurations of the reaction disk 201, constant temperature unit 202, rack sampler 203, reagent storage unit 204, sample dispensing arm 206, sample dispensing probe 207, reagent dispensing arm 208, and reagent dispensing probe 209 in the second embodiment are equivalent to those in the first embodiment, and therefore their description is omitted.

Furthermore, the analysis mechanism 2B according to this embodiment includes a reaction tube transport arm 210 and a waste box 214. Although the reaction tube supply unit 211 and the light intensity measurement jig 212 are omitted from Figure 16, the analysis mechanism 2B of the automatic analyzer 1 according to the third embodiment may also include a reaction tube supply unit 211 and a light intensity measurement jig 212, similar to the first and second embodiments described above. The configuration of the waste box 214 is the same as in the second embodiment, so its description is omitted.

In this embodiment, the reaction tube transport arm 210 transports used reaction tubes 2011 from the reaction tube installation position on the reaction disk 201 to the reaction tube disposal position on the waste box 214, such that the reaction tube holding portion 2101 of the reaction tube transport arm 210 and the used reaction tubes 2011 held by the reaction tube holding portion 2101 pass through the transport path. The other configurations of the reaction tube transport arm 210 are the same as those of the first embodiment described above, and therefore will not be described further.

Furthermore, in the analysis mechanism 2B according to this embodiment, the same number of photometric units 213 as the number of reaction tubes 2011 that can be held in the reaction disk 201 are provided inside. These photometric units 213 constitute the photometric section in this embodiment. The configuration of these photometric units 213 is the same as that of the first embodiment, and therefore, a detailed explanation is omitted.

The control circuit 9B shown in Figure 15 implements the functions corresponding to the control program stored in the memory circuit 8 by executing the program. For example, the control circuit 9B has a system control function 91, a second control function 97, a second determination function 98, and a third reporting function 99 by executing the control program. In this embodiment, the case in which the system control function 91, the second control function 97, the second determination function 98, and the third reporting function 99 are implemented by a single processor is described, but this is not the only case. For example, the control circuit may be configured by combining multiple independent processors, and these various functions may be implemented by each processor executing a control program. Furthermore, the functions of the system control function 91 in this embodiment are equivalent to those of the system control function 91 shown in Figure 1, so their explanation is omitted.

The second control function 97 controls the reaction tube transport arm 210 and the imaging unit 2103 located on the reaction tube transport arm 210 by controlling the analysis mechanism 2B and the drive mechanism. Specifically, the second control function 97 controls the reaction tube transport arm 210 to remove the used reaction tube 2011 from the reaction disk 201, transport it to the reaction tube disposal position in the waste box 214, and control the imaging unit 2103 of the reaction tube transport arm 210 to image the used reaction tube 2011.

The second determination function 98 analyzes the image of the used reaction tube 2011 captured by the imaging unit 2103 controlled by the second control function 97, and determines whether or not there is an abnormality in the used reaction tube 2011. Specifically, the second control function 97 analyzes the image of the used reaction tube 2011 captured by the imaging unit 2103 to determine whether or not there are bubbles or other abnormalities on the liquid surface of the used reaction tube 2011, and determines whether or not there is an abnormality.

The third reporting function 99 reports to the user that there is an abnormality in the used reaction tube 2011 when the second judgment function 98 determines that there is an abnormality in the used reaction tube 2011. Specifically, when the second judgment function 98 determines that there is an abnormality in the used reaction tube 2011, the third reporting function 99 reports to the user via the output interface 6 that there is an abnormality in the used reaction tube 2011.

Furthermore, the system control function 91, second control function 97, second determination function 98, and third reporting function 99 shown in Figure 15 constitute the system control unit, second control unit, second determination unit, and third reporting unit, respectively, in this embodiment.

Figure 17 is a flowchart illustrating the contents of the spent reaction tube imaging process performed by the automated analyzer 1 according to this embodiment. This spent reaction tube imaging process involves imaging the spent reaction tube 2011, analyzing the captured images, and reporting the results to the user. For example, this spent reaction tube imaging process is executed at the time the spent reaction tube 2011 is being transported by the reaction tube transport arm 210.

As shown in Figure 17, first, the automatic analyzer 1 moves the reaction tube transport arm 210 to the reaction disk 201 (step S101). This process of moving the reaction tube transport arm 210 to the reaction disk 201 is realized by the second control function 97 in the control circuit 9B. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to move the reaction tube holding portion 2101 of the reaction tube transport arm 210 to the reaction tube placement position on the reaction disk 201.

Next, as shown in Figure 17, the automatic analyzer 1 holds the used reaction tube 2011 (step S103). This process of holding the used reaction tube 2011 is realized by the second control function 97 in the control circuit 9B. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to hold the used reaction tube 2011 using the reaction tube holding section 2101 of the reaction tube transport arm 210.

Next, as shown in Figure 17, the automatic analyzer 1 images the used reaction tube 2011 (step S105). This process of imaging the used reaction tube 2011 is realized by the second control function 97 in the control circuit 9B. Specifically, the automatic analyzer 1 controls the imaging unit 2103 to image the used reaction tube 2011 when the reaction tube transport arm 210 transports the used reaction tube 2011.

Next, as shown in Figure 17, the automated analyzer 1 analyzes the image of the used reaction tube 2011 (step S107). This image analysis is performed by the second determination function 98 in the control circuit 9B. Specifically, the automated analyzer 1 analyzes the image of the used reaction tube 2011 captured in step S105 to determine if there are any abnormalities such as bubbles.

Next, as shown in Figure 17, the automated analyzer 1 determines whether or not there is an abnormality in the used reaction tube 2011 (step S109). This determination process is implemented by the second determination function 98 in the control circuit 9B. Specifically, the automated analyzer 1 determines whether or not there is an abnormality in the liquid level, etc., of the used reaction tube 2011 based on the analysis results of the image of the used reaction tube 2011 taken in step S107.

Figure 18 is a schematic diagram showing an example of a case where there is an abnormality in the used reaction tube 2011 in the automatic analyzer 1 according to this embodiment. As shown in Figure 18, the used reaction tube 2011 is held in the reaction tube holding section 2101 of the reaction tube transport arm 210. In the example shown in Figure 18, a bubble BU is present on the liquid surface of the used reaction tube 2011. When a bubble BU is present on the liquid surface of the used reaction tube 2011 in this manner, the used reaction tube 2011 is determined to be abnormal.

Then, in step S109, if it is determined that there is an abnormality in the used reaction tube 2011 (step S109: Yes), the automatic analyzer 1 reports the abnormality in the used reaction tube to the user (step S111). This reporting process is realized by the third reporting function 99 in the control circuit 9B. Specifically, the automatic analyzer 1 reports the abnormality in the used reaction tube 2011, which was imaged in step S85, via the output interface 6.

After the processing in step S111, or if it is determined in step S109 above that there is no abnormality in the used reaction tube 2011 (step S109: No), the automatic analyzer 1 transports the used reaction tube 2011 to the reaction tube disposal location (step S113). This transport to the reaction tube disposal location is realized by the second control function 97 in the control circuit 9B. Specifically, the automatic analyzer 1 controls the reaction tube transport arm 210 to transport the used reaction tube 2011 to the reaction tube disposal location in the waste box 214.

Next, as shown in Figure 17, the automated analyzer 1 discards the used reaction tube 2011 (step S115). This disposal of the used reaction tube 2011 is achieved by the second control function 97 in the control circuit 9B. Specifically, the automated analyzer 1 controls the reaction tube transport arm 210 to store the reaction tube 2011 held in the reaction tube holding unit 2101 into the waste box 214, thereby discarding the reaction tube 2011.

By executing step S115, the used reaction tube imaging process according to this embodiment is completed.

As described above, according to the automatic analyzer 1 of this embodiment, when the reaction tube transport arm 210 is controlled to transport the used reaction tube 2011 to the reaction tube disposal position, the used reaction tube 2011 is imaged to determine whether or not there is an abnormality in the used reaction tube 2011. If there is an abnormality such as bubbles in the liquid surface inside the used reaction tube 2011, the system reports the abnormality to the user, allowing the user to know whether or not they were able to obtain accurate measurement results.

In the above explanation, the term "processor" refers to circuits such as a CPU (Central Processing Unit), GPU (Graphics Processing Unit), Application Specific Integrated Circuit (ASIC), or programmable logic device (e.g., Simple Programmable Logic Device (SPLD), Complex Programmable Logic Device (CPLD), and Field Programmable Gate Array (FPGA)). A processor functions by reading and executing a program stored in a memory circuit. Alternatively, instead of storing the program in a memory circuit, the program may be directly embedded within the processor's circuitry. In this case, the processor functions by reading and executing the program embedded within the circuitry. Furthermore, a processor is not limited to being a single circuit; it may be composed of multiple independent circuits combined to form a single processor and achieve its functions. Additionally, multiple components may be integrated into a single processor to achieve its functions.

While several embodiments have been described above, these embodiments are presented only as examples and are not intended to limit the scope of the invention. The novel apparatus and methods described herein can be implemented in various other forms. Furthermore, various omissions, substitutions, and modifications can be made to the embodiments of the apparatus and methods described herein, without departing from the spirit of the invention. The appended claims and equivalents are intended to include such forms and modifications included in the scope and spirit of the invention.

1…Automatic analyzer, 2, 2A, 2B…Analysis mechanism, 3…Analysis circuit, 4…Drive mechanism, 5…Input interface, 6…Output interface, 7…Communication interface, 8…Memory circuit, 9, 9A, 9B…Control circuit, 91…System control function, 92…First control function, 93…Measurement function, 94…First reporting function, 95…First judgment function, 96…Second reporting function, 97…Second control function, 98…Second judgment function, 99…Third reporting function,

Claims (10)

The reaction tube installation section where the reaction tubes are installed,
A reaction tube transport mechanism for transporting the reaction tube,
The reaction tube transport mechanism includes an imaging unit,
A first control unit controls the reaction tube transport mechanism to transport the reaction tube to the reaction tube installation section and causes the imaging unit to image the reaction tube,
A light-emitting unit that emits light so as to irradiate the reaction tube,
A light intensity measuring jig used to measure the light intensity of the light-emitting part,
In the reaction tube installation section, the imaging unit measures the amount of light from the light-emitting section received via the light intensity measuring jig,
A first reporting unit that reports the measurement result of the light intensity of the light-emitting unit, and if the measurement result of the light intensity of the light-emitting unit is outside a predetermined range, the first reporting unit reports that the measurement result of the light intensity of the light-emitting unit is outside a predetermined range,
An automated analyzer equipped with the following features. The automatic analyzer according to claim 1, wherein the measuring unit measures the height of the optical axis of the light-emitting unit, which is the height from the bottom surface of the light-intensity measuring unit to the optical axis of the light-emitting unit, based on the light-receiving position, which is the position within the imaging unit where the imaging unit receives light irradiated from the light-emitting unit, when the light-intensity measuring jig is installed in the reaction tube installation unit. The automatic analyzer according to claim 1, wherein the measurement unit, while the light intensity measuring jig is transported above the reaction tube installation unit, controls the reaction tube transport mechanism to lower the light intensity measuring jig, and measures the height of the optical axis of the light-emitting unit, which is the height from the bottom surface of the light intensity measuring jig to the optical axis of the light-emitting unit, based on the amount of descent of the light intensity measuring jig when the imaging unit receives light emitted from the light-emitting unit at a predetermined position within the imaging unit. The automated analyzer according to claim 2 or 3, wherein the first reporting unit reports the measurement result of the optical axis height of the light-emitting unit. The automatic analyzer according to claim 4 , wherein the first reporting unit reports that the measurement result of the optical axis height of the light-emitting unit is outside a predetermined range when the measurement result of the optical axis height of the light-emitting unit is outside a predetermined range. The automatic analyzer according to any one of claims 1 to 5 , wherein the first control unit controls the imaging unit to image the reaction tube when the reaction tube transport mechanism transports the reaction tube. The automatic analyzer according to claim 6, further comprising a first determination unit that controls the imaging unit to analyze the image of the reaction tube captured by the first control unit and determines whether or not the reaction tube is usable. The automatic analyzer according to claim 7, wherein the first control unit controls the reaction tube transport mechanism to transport the reaction tube to the reaction tube installation unit when the first determination unit determines that the reaction tube is usable. The automatic analyzer according to claim 7 or 8, wherein the first control unit controls the reaction tube transport mechanism to transport the reaction tube to a reaction tube disposal position, which is a position for discarding the reaction tube , when the first determination unit determines that the reaction tube is unusable. The automated analyzer according to claim 9 , further comprising a second reporting unit that reports that the reaction tube should be discarded when the first determination unit determines that the reaction tube is unusable.