JPS5840923B2 - Hair nourishing composition - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a hair nourishing composition containing a specific crude drug extract as an essential ingredient.

Various hair growth agents have been used for the prevention and treatment of alopecia.

There are various symptoms of alopecia, and the causes and hair loss mechanisms are as follows:
Although it is still largely unknown, when looking at alopecia comprehensively, certain abnormalities occur in various parts of the skin, including the capillary system, the epidermal system, and the epidermal system.

Therefore, hair tonics contain various medicinal agents that have the effect of preventing or suppressing these abnormalities, such as various fungicides, keratolytic agents such as salicylic acid and resorcinol, female hormones, vitamins such as vitamin E and biotin, and serine. It contains amino acids such as methionine and methionine, vasodilators such as nicotinic acid derivatives and acetylcholine derivatives, and skin function-enhancing agents such as cepharanthine and photosensitive pigments.

However, when applied externally, hair tonics exert their effectiveness by preventing or suppressing dandruff, itching, and dead hair, and by promoting hair growth and growth, but none have yet been found to be fully satisfactory.

While carrying out various studies on medicinal agents that have a hair-growth effect, the present inventors discovered that certain crude drugs have an excellent hair-growth effect, and thus completed the present invention.

That is, the present invention provides a hair tonic composition containing as an essential ingredient an extract of a herbal medicine selected from Japanese wolfberry, wolfberry, saiko, kuzu, and water leech, and the hair tonic composition of the present invention exhibits extremely excellent performance. have

Next, the results of testing the hair growth effects of various crude drug extracts are shown.

The crude drug extract sample was prepared by extracting the shredded crude drug powder twice with 50% ethanol, filtering, and concentrating to dryness, and dissolving the residue in 70% ethanol to prepare a 2% (W/V) solution.

The test was conducted using a newly developed mouse hair growth measurement method.

That is, 9 to 11 5-week-old ddY male mice were
The left and right buttocks of each mouse were removed as a group, and the right side was treated with 70% ethanol as a control side, and the left side was treated with crude drug extracts as a test side, 0.1 rul each, twice a day.
After application for 10 days, the hairs on both sides were pulled out and the difference in average hair length between the control side and the test side was examined to examine the effect of the herbal medicine extract on mouse body hair growth.

The results are shown in Table 1 below.

As is clear from the results in Table 1, 薊芊, wolfberry, saiko, yōkuzu, and water hiru, especially shiba ko and water hiru, have excellent hair growth effects.

It should be noted that although hair growth is also excellent in hair growth effects, it is not preferable because it causes local subacute or chronic inflammation.

Thus, the composition of the present invention preferably contains an extract of one or more crude drugs selected from Physcomitrella japonica, Lycium japonica, Chaigu, calyx, and water lichen, preferably in an amount of 0.01 to 0.01 to 0.01 or more based on the total weight of the composition. 3
Add 0% by weight.

The extract to be used may be obtained by a conventional method, for example, extracting a single powder of shredded fresh leaves or a mixture of several types with aqueous ethanol several times, filtering this extract, and concentrating to dryness. can be obtained.

Alternatively, a purified extract obtained by further purifying this extract by subjecting it to dialysis or chromatography may be used.

The hair tonic composition of the present invention can be made into conventional dosage forms such as hair tonics, hair lotions, hair creams, shampoos, and conditioners according to conventional methods.

Other ingredients may be those that are normally used in the production of these products, such as distilled water, alcohols, polyhydric alcohols, oils and fats, surfactants, etc. as a base,
In addition, as medicinal ingredients, resorcinol, hormones,
Vitamins, nicotinic acid derivatives, photosensitive pigments, amino acids, bactericides, menthol, and other fragrances may also be added.

Next, the present invention will be explained in more detail with reference to Examples, but the present invention is not limited thereto.

In addition, in each example, the term "parts" means parts by weight.

Example 1 A hair tonic with excellent hair growth effects was produced by a conventional method according to the following recipe.

Prescription 95% ethanol solubilizer [polyoxyethylene hydrogenated castor oil (60EO)] Fragrance J1 Seed extract Distilled water 50 parts 1 part 0.5 part 1 part 47.5 parts Example 2 According to the following recipe, by a conventional method, A hair lotion with excellent hair growth effects was produced.

Formula Stearic acid (63°C) Setanol Preservative and fragrance Triethanolamine Glycerin (Grincoderm) extract Anthracite (Thorn) extract 95% Ethanol 5 parts Distilled water 0.5 parts Emulsifier [Polyoxyethylene (20EO) Sorbitan sesquis Oleate] 0.8 parts 1 part 0.4 parts 5 parts 3 parts 7 parts 8 parts Total amount adjusted to 100 parts Example 3 A hair cream with excellent hair growth effect was produced according to the following formulation and a conventional method.

Formula: Beesuro Lanolin (Anhydrous) Vaseline: 5 parts Liquid Paraffin: 4 parts: 5 parts: 33 parts: Formula: Emulsifier [Polyoxyethylene (20EO) Sorbitan Monostearate]: 4 parts: Preservatives and Fragrances
1 part saiko extract
10 parts water leech extract
5 parts Aji (peeling) extract
Part 5 Borax 1
Part propylene glycol 5 parts Distilled water Adjust the total amount to 100 parts Example
4. A shampoo with excellent hair growth effects was produced by a conventional method according to the following formulation.

prescription sodium lauryl sulfate Magnesium stearate polyvinyl alcohol cetyl alcohol lanolin glycerin laurate Leech extract Distilled water 35 copies 4th part Part 1 2nd part Part 1 2nd part 0.05 part Adjust the total amount to 100 copies

Claims (1)

[Scope of Claims] 1. A hair nourishing composition comprising, as an essential ingredient, an extract of one or more crude drugs selected from Aji, Lycium, Chaigu, Senji, and Suzuhiru. 2. The composition according to item 1 above, wherein the herbal medicine is saiko and/or water leech. 3 The crude drug extract is added in an amount of 0.01 to 3 based on the total weight of the composition.
The composition of item 1 above containing 0% by weight.