JPS5843363B2 - sun protection agent - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to natural KARITE (scientific name: But).
The present invention relates to a sunscreen agent characterized in that it contains oil and fat obtained from the fruit of P. yrospermum Parkii.

In recent years, due to changes in the social structure, opportunities for direct exposure to sunlight in daily life have been greatly reduced, and the tendency to seek sunlight to improve health is becoming more and more common.

However, the so-called ultraviolet rays with a wavelength of 200 to 400 mμ in sunlight cause physiological reactions such as the occurrence of erythema and reversible pigmentation on the skin, and when suddenly exposed to strong sunlight, it can cause discomfort and pain. This can lead to excessive sunburn, which can lead to symptoms of a type of burn such as reddening of the skin and water blisters.

In order to prevent such undesirable reactions caused by ultraviolet rays and to limit the deposition of melanin pigments to a level that gives a desirable healthy color, cosmetics that contain substances that absorb ultraviolet rays in the sun's rays are generally sold as commercial products. has been made into

Conventional sunscreen cosmetics contain para-aminobenzoic acid and its lower alcohol ester, and 2-ethoxyethyl 4-methoxycinnamate as active ingredients.

2-Hydroxy-4-methoxybenzophenone.

2-(2-hydroxy-4-methoxy)benzophenone, 2-(2-bitroxy-5-methylphenyl)benzotriazole, etc. are used.

Since these are all chemically synthesized products, the maximum amount of these in cosmetics is regulated in consideration of their adverse effects on the human body.

Therefore, the amount of active ingredients used is limited, and at present it has not been possible to obtain a sufficiently satisfactory sun protection effect.

The present inventor selected 200 to 40 natural products from highly safe natural products.
We searched for substances that absorb ultraviolet rays with wavelengths of 0 mμ and hoped to find highly effective sunscreens by blending natural products that are harmless to the human body in arbitrary proportions.

Oils and fats conventionally used as skin cosmetics to protect the skin include olive oil, beef tallow, lard, cacao butter, sesame oil, lanolin, parcellin oil, jojoba oil, camellia oil, castor oil, and turdle oil.

This type of oil has the effect of preventing skin dryness, softening the skin by permeating into the stratum corneum, and providing nutrition. It is thought that the absorption of ultraviolet light by these oils and fats is not noticeable even when measured with a spectrophotometer.

As a result of testing a large number of natural oils and fats, the present inventor found that the oil obtained from the Karite fruit (hereinafter referred to as "Karite (also known as "shea") butter) has a remarkable ultraviolet absorption effect and is useful in cosmetics. We obtained the knowledge that it is suitable as a raw material, and based on this, we completed the present invention.

Karite butter is an oil and fat obtained by hot-mulling the walnut-sized seeds of the Karite plant, which grows wild in the Senegal region of Africa.

The appearance of this oil is a soft ant-like solid with a light yellowish brown color, and it has a unique aroma, and is mainly eaten by native peoples.

Its properties as a fat and oil are as follows.

Acid value 6.41 Saponification value 185.9 Iodine value 52.2 Non-saponifiable substance 8% Melting point 33.5°C Vitamin A 14411 [J/, 9 Vitamin F100TII? /g Sterols 2.2 /g Karite Butter 0.1. ! Dissolve i+ in 1019 cyclohexane and use a spectrophotometer (manufactured by JASCO Corporation, (JVI
When measuring the ultraviolet absorber with DEC-1 type), it is approximately 24
Absorption is seen at wavelengths of 0 to 300 mμ, especially at wavelengths of 270 to 2
A sharp absorption curve showing an absorption rate of about 50φ between 75 mμ can be confirmed.

Moreover, this substance has a stinging effect on the skin. It does not cause any harmful effects such as rash.

When blending Karite butter into a sunscreen, cream is prepared using generally known methods.

It can be used as a cosmetic in the form of an ointment, gel, oil, or the like.

The amount of karite butter to be blended is arbitrary and may be determined by considering factors such as the form of the cosmetic, and is usually used in a range of about 10 to 70 weight φ.

At this time, other ultraviolet absorbers may be blended, and appropriate amounts of fragrances, two pigments, and preservatives may be added. , I tried the following experiment.

That is, a cream containing 20 parts by weight of karite butter was prepared, and on the other hand, a cream containing cacao butter in place of karite butter was prepared.

Furthermore, 50% of ethyl vanillin, which changes color when exposed to ultraviolet rays,
One weight of a heavy ethanol solution was added to each sample and stirred thoroughly.

This was packed in a container made of white urea resin with a diameter of 5 cIrL and a depth of 1 cIrL, the surface was covered with a transparent film (product name: "Saran Wrap", manufactured by Asahi Dow Corporation), and a Toshiba H40 was placed in the container.
0F fading test lamp (light wavelength = 250 to 600 mμ
) was irradiated with light for 1 hour from a distance of 30 crrL.

As a result, the color tone of items made with Karite butter is determined using the Pantone Matching System (PantoneMac).
hing system), it was 155°C, whereas the color tone using cocoa butter was equivalent to 474U.

In view of this color difference, it was found that the color density of the product using Karite butter was approximately one-third that of cacao butter.

This shows that sunburn can be reduced by about one-third.

Furthermore, a cream containing 20% more weight of Karite putter was applied to the left side of the back of a 25-year-old man, Japanese Pharmacopoeia olive oil was applied to the right side, and the two were exposed to the September sun for 2 hours for comparison. .

As a result, the skin on the right side to which the olive oil had been applied had a significant degree of redness, developed blisters the next day, and the epidermis in that area peeled off four days later.

On the other hand, the skin on the left side to which the cream containing Karite butter was applied became red and sunburned, but the symptoms were mild and no blistering occurred.

The above experiments confirmed that Karite butter is effective in preventing sunburn.

The present invention will be explained below with reference to Examples.

Example 1 (Cream) (Weight φ) A oil phase: Karite butter 20.07 Rough-in 8.0 Beeswax
4.0 Stearic acid 4.0 Sorbitan monooleate 3.0 Liquid paraffin 10.0 Butyl paraoxybenzoate 0.2 B aqueous phase nitriethanolamine 0.4 Purified water
50.4 According to the above recipe, mix each component of the oil phase of A and make about 8
The mixture was heated to 0° C., and the components of the aqueous phase of B at the same temperature were added while stirring.

After making it sufficiently homogeneous, it was cooled while stirring gently, and when the temperature reached about 40°C, it was poured into a container to make a sunscreen cream.

Example 2 (Ointment) (Weight) Carite butter 40 Olive oil 20 Beeswax 20 Tumarafine 20 Each component was mixed according to the above recipe, heated to about 70°C and stirred well.

After making it sufficiently homogeneous, it was poured into a container and left to cool to make an ointment.

Example 3 (Ointment) (Weight) Carite butter 60 Castor oil 10 Liquid paraffin 10 Beef tallow 20 An ointment was made in the same manner as in Example 2 according to the above recipe.

Example 4 (Oil) (Weight φ) Caritebata-50 (Weight) Isopropyl myristate 50 According to the above recipe, the ingredients were mixed, heated to about 70'C, stirred well, and made sufficiently uniform. , gradually cool down,
I made some sunscreen oil in a container.

Example 5 (Cream) (Weight cake) A oil phase: Caritebac-15.0 Lanolin 3.0 Stearic acid 8.0 Norafuin 5.0 Glyceryl monostearate 3.0 Liquid paraffin 10.0 Propyl paraoxybenzoate 0.3 Aqueous phase B: Potassium hydroxide O16 purified water 55.1 A sunscreen cream was prepared in the same manner as in Example 1 according to the above recipe.

Claims (1)

[Claims] 1. A sunscreen agent characterized by containing oil and fat obtained from Karite fruit.