JPS5852184B2 - Saliva pH measurement method - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention provides a simple method for measuring saliva pH.

Body fluids such as human blood and lymph are weakly alkaline when healthy, but when the body is sick or fatigued, acids such as lactic acid or pyruvic acid accumulate, making them temporarily acidic, and as the body recovers, they become slightly alkaline again. It is known that it will return to

On the other hand, human saliva is also slightly alkaline, but common sense has believed that this does not change depending on the state of the body's health.

To date, there has been little academic research on saliva.

The present inventors focused on the possibility that the pH of human saliva changes depending on the state of health, and investigated oral changes in saliva using a panel of 20 people.

This panel test will be discussed in detail below.

As a result, it was found that the pH of human saliva changes considerably compared to rice.

It was confirmed that changes can be seen depending on the time even on the same day.

Although it varies from person to person, the pH of saliva varies from about 5.5 to 7.
It was in the range of 8.

It can be said that there is currently no research data on the relationship between food or human health status and the pH of saliva.

Regarding foods, for example, alkaline foods have a relatively high calcium content, but have a low phosphorus content, making it easier to keep the body fluids of those who eat them slightly alkaline.

Conversely, acidic foods tend to make body fluids more acidic.

Such empirical assumptions regarding foods are generally accepted.

In discussions about food, it is more important to eat a balanced diet than to think that acidic foods are bad for the human body, while alkaline foods are good and greatly contribute to health.

To this end, it is important to know for yourself whether your constitution is acidic or alkaline.

Knowing this can lead to improvements in the person's eating habits.

The present inventors decided to estimate the constitution by knowing the pH of saliva, which is a type of lymph fluid, and completed the present invention.

From the results of the panel test mentioned above, it seems that the pH of saliva has some relationship with the health condition of the day.

That is, it is thought that knowing the health condition of the person based on changes in the pH of saliva, and by extension knowing the condition of the person, can be used to help improve eating habits.

Various methods have been introduced in the past for measuring the pH of liquids.

For example, there is a method using a commercially available pH meter.

However, since the use of a pH meter requires a certain amount of liquid or more, this is inappropriate for measuring the pH of saliva.

The easiest way to measure the pH of saliva is to use a commercially available pH test paper such as Lidomus test paper.

However, since this lidmus test paper is a paper whose surface is coated or impregnated with chemicals, it is not hygienic to measure the pH of saliva by directly licking it, as is the usual method of using lidmus paper.

The present inventors have determined that it is appropriate to use this lidmus test paper indirectly, and that chewing gum (hereinafter referred to as gum)
I thought of the combination with Lidmus test paper.

The present invention is a method for measuring the pH of saliva, which consists of contacting gum with saliva attached to lidmus test paper.

Specifically, when discarding gum that has been thoroughly chewed in the mouth and coated with saliva, the pH of the saliva is determined by contacting it with Lidomus test strips incorporated in the gum wrapping paper and checking the color change of the test strips. This is a way to know.

The present invention will be explained in more detail below.

The gum that is an intermediate medium for measuring the pH of saliva is preferably a neutral gum because of its intended use.

Regular gums on the market include gum base, sweetener,
Its ingredients include fragrances and organic acids.

These have only the purpose of confectionery and contain additives according to taste.

The final product can be acidic, alkaline, or neutral.

One of the features of the present invention is that neutral gum is used as a medium.

It is necessary that the gum medium does not have any influence on the natural pH value of saliva.

All gum raw materials used for this purpose should be neutral, or at least the final product should be neutral.

Furthermore, it is necessary that the gum made from these raw materials does not become acidic or alkaline upon contact with saliva, that is, due to various enzymes contained in saliva.

For the above reasons, neutral gums should be free of organic acids that are commonly used in gums and give the product a sour taste.

As long as there is no change in the pH of the gum itself before and after chewing the gum, the pH of the gum itself does not necessarily have to be neutral by appropriately selecting a pH indicator.

The gum base of the neutral gum used in the present invention includes natural resins such as chicle, vinyl acetate, waxes, polybutene, ester gums, and the like.

The neutral gum sweetener used in the present invention includes powdered sugar, fructose, glucose, sorbitol, reduced maltose, coupling sugar, steviocyto, and the like.

Further, in order to retain a large amount of saliva in the gum, it is preferable to add natural polysaccharides such as guar bean gum and locust bean gum, or proteins such as gluten and casein.

Other raw materials for the neutral gum used in the present invention include commonly used fragrances, emulsifiers, and the like.

The neutral gum used in the present invention can take any form of conventional gum commercially available.

Any conventional method can be used to produce the neutral gum used in the present invention.

As is clear from the results of the panel test described below, the pH test paper used in the present invention has a pH around neutral, particularly in the pH 5 to pH 8 range.
This is a test paper that can be used to accurately determine the

Among the commercially available lidmus test strips having this property, for example, BCP (bromocresol purple),
BTB (bromothymol blue), P
R (phenolred) etc. alone and MR-
BTB (methylred-bromothymo
l blue), BCG-BTB (bromocres
ol green -bromothymolblue
) is preferred.

One mode of use of the above-mentioned Lidomus test strip is shown in FIG.

This is about 0.7 to 1.2 CrrL for normal gum wrapping paper.
X about O33~0.6 crrt1 preferably about 0.8c
This is an example in which a space of approximately 0.5 cIIL is provided, and lidmus test paper is pasted in this space.

The shape of the space is not limited to a rectangle, but can include triangles, squares, circles,
Any shape such as an ellipse may be used.

Another form of use as a pH test paper is shown in Figure 2. This is an example in which the usual gum wrapping paper is not used, but a water-absorbent paper is used instead, and a certain part of the paper, such as the middle, is used. This is an example of applying the above-mentioned pH reagent and using this paper as a pH test paper and wrapping paper.

There are no particular limitations on the area and location of application.

The amount of the reagent applied is not particularly limited as long as it is sufficient for measuring the pH of saliva.

Both of the above two usage forms have the advantage that chewed gum is wrapped in the paper in the mouth and the pH of the saliva can be determined from the outside.

In any of the above usage forms, care is taken to prevent the gum from coming into direct contact with the pH test paper or reagent.

The usage form of the pH test paper is not limited to the above two examples.

As another embodiment, it is also possible to insert several sheets of pH test paper of an appropriate size, preferably the number of sheets of gum board, between each packaged gum, either all at once or separately. be.

In any of the above embodiments, a color change chart of standard primary colors is printed or affixed on the outer box of the gum or printed or affixed on the wrapper of each gum board, and the pH of the saliva is determined. It will be offered to

According to the present invention, as described above, after enjoying the gum itself in the same way as regular gum, it is possible to easily know one's own health condition on that day, which is a novel gum that was completely unknown in the past. Provides ways to have fun.

Hereinafter, the present invention will be explained in more detail using specific examples together with the test results of oral changes in saliva.

Test example A panel test was conducted to examine oral changes in saliva.

A panel of 20 people (12 men, 4 women, and 4 children) determined the pH of each person's saliva using the BTBIJ Thomas test paper described above.

The test period was about 2 weeks, and tests were conducted once or twice a day.

The results are shown in Table 1.

The results revealed that the pH of human saliva varies considerably from time to time, even on the same day.

The pH range was from about pH 5.5 to about pH 7.8.
In addition, when a considerable amount of saliva was directly measured with a pH meter for a follow-up test, the results were almost the same as those in Table 1.Example 1 A small mixer was heated at 60°C.

Transfer 150g of neutral raw material gum base that was well melted and mixed at 120°C into this, then gradually add 400g of powdered sugar, 100g of glucose, 3og of starch syrup, 7g of sorbitol, and 5g of gluten, and mix until homogeneous. do.

Finally, add 2g of menthol and 4g of peppermint flavor, mix well, then remove from the mixer and cut into pieces.

If you chew this gum in your mouth for 3 minutes and then apply it to a BTB lidmus test strip, people with an acidic constitution (the pH of their saliva is acidic) will see the lidmus test strip turn yellow, while those with an alkaline constitution (the pH of their saliva is alkaline) ) will turn blue for people with this condition.

Example 2 Using di-reduced maltose aqueous solution, sorbitol and steviocyto instead of sugar to make sugarless gum.

200g of gum base made from neutral raw materials with high elasticity
Melt at 00°C and place in a small mixer kept at 60°C, add 200g of powdered sorbitol, 5 steviocyto
00■, reduced maltose 100g, locust bean gum 5
After gradually adding g1 and kneading well, 2 g of menthol and 4 g of cinnamon flavoring were added and mixed well.

This mixture is taken out from the mixer, rolled and cut appropriately.

If you chew this gum in your mouth for 3 minutes and then apply it to an MR-BTB mixed lidmus test strip, it will turn red for people with acidic constitutions, and blue for people with alkaline constitutions.

[Brief explanation of drawings]

FIG. 1 is a diagram showing the lidmus test paper used in the present invention incorporated into gum wrapping paper. FIG. 2 is a diagram showing a state in which the lidmus reagent used in the present invention is applied to gum wrapping paper.

Claims (1)

[Claims] 1. A method for measuring the pH of saliva, which is characterized by bringing saliva-resistant chewing gum into contact with pH test paper.