JPS5930422B2 - biological tissue collector - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a biological tissue sampler, and particularly to a sampler suitable for removing and collecting a specimen of pathological tissue for uterine cancer screening.

Currently, histopathological examination is indispensable as a means of uterine cancer screening, and is also extremely important as a definitive diagnosis method. Therefore, obtaining a good specimen is an important condition for diagnosis.

However, in the field of gynecology, the so-called punch biopsy method has been used as a resection device for pathological tissue examination of the uterine arm, which involves grasping and cutting the tissue, which has various problems.

In other words, this resection method involves pressing a blade shaped like a ``crocodile's mouth'' onto the tissue to be removed, grasping it, and cutting it off.

Therefore, depending on how much pressure is applied, it may slip and destroy the epithelium, the resected specimen may be too thin, or the resected tissue may be crushed, resulting in inconvenience for diagnosis.

Since the aim of early detection of uterine cancer is to know the degree of spread of the initial cancer is extremely important in determining the surgical method, and the boundary between carcinoma in situ and invasive cancer is particularly important.

It has been extremely difficult to reliably excise and harvest such areas using the conventional punch biopsy method.

SUMMARY OF THE INVENTION An object of the present invention is to solve the problems of conventional tissue excision collectors and to provide a collector that can easily collect biological tissue at a predetermined depth even without special skill.

The collector of the present invention will be described in detail below along with an explanation of the drawings showing an example thereof.

Fig. 1 is a plan view of an example of the collector of the present invention, Fig. 2 is a side view of the device shown in Fig. 1, and Fig. 3 is a side view of the front part (left part in Fig. 1) of the device shown in Fig. 1. Figure 4 is a plan view of the front part, Figure 5 is a perspective view of the front part with the tubular blade and flat blade removed, and Figure 6 shows the collector shown in Figure 1. 7 is a plan view of the portion shown in FIG. 6, FIG. 8 is a cross-sectional view taken along line I-I in FIG. 7, and FIG. 9 is a side view of the front portion of the holding body. It is a side view of the front part of the sliding rod which constitutes the extractor shown, Comprising: It is also an explanatory view showing the point of attaching a flat blade to this part.

Figure 10 is a plan view of the flat blade used in the collector shown in Figure 1, Figure 11 is a schematic perspective view showing the flat blade attached to the front part of the sliding rod, and Figure 12. 1 is a side view of the tubular blade used in the collector shown in FIG. 1, FIG. 13 is a plan view of the blade shown in FIG. 12, FIG. 14 is a perspective view of the blade shown in FIG. 12, and FIG. FIG. 12 is a cross-sectional view taken along the line ■--■, and FIG. 16 is a schematic perspective view of the tip of the collector shown in FIG.

The main components of the collector of the present invention are (a) an elongated sliding rod;
(b) A rod-shaped holder that holds this sliding rod so that it can move back and forth in its axial direction; (c) A tubular portion provided at the front part of the holder is missing in its axial direction. It consists of a shaped blade (hereinafter referred to as the tubular blade) and a flat flexible blade (hereinafter referred to as the flat blade) provided at the front part of the sliding rod.

Furthermore, a guide portion for the flat blade is provided so that the flat blade moves while maintaining a specific relative positional relationship with respect to the tubular blade.

The holder 2 is in the shape of an elongated rod as shown in FIG. 1.2, and as seen in the cross section shown in FIG. 8, it has a hollow portion, that is, it has a tubular shape.

An elongated sliding rod 1 is inserted into the hollow portion, and the sliding rod 1 can freely move back and forth within the hollow portion of the holder 2.

As shown in FIGS. 12, 13, and 14, the tubular blade 4 has a shape in which a portion of the tubular shape is missing in the axial direction. The tip is thin to make it easier to cut into living tissue, but the rear part is thicker, making it difficult to deform the tubular blade, and at the same time, the front part 3 of the holder 2 is It serves as a fixing part 6 for fixing the blade 4.

The front part 3 of the holder 2 is tapered.

That is, its thickness is the thickness of the portion below the hollow portion of the cross section shown in FIG. 8, and the width is also smaller (see FIGS. 3, 4, and 5).

A tubular blade 4 is fixed to this narrowed portion.

In other words, the partially missing portion of the tubular blade 4 is positioned upward, and the fixed portion 6 of the tubular blade 4 surrounds the front portion of the holder 2 as shown in FIGS. 3 to 5.

Then, the split pins 10 and 11 are passed through the split pin insertion lower and 7' of the fixing portion 6, respectively, and then through the through holes 14 and 14' provided in the front portion 3 of the holder 2, thereby fixing the tubular blade.

On the other hand, the flat blade 4 has a flat shape, and this one has the sliding rod 1.
attached to the front part of the

As shown in FIGS. 5 and 9, the front part of the sliding rod 1 is stepped and thinned, and a flat blade 5 is placed on the top surface of this thinned part. A presser plate 19 is further placed on top of 5, and the presser bolts 17 and 18 are passed through through holes 20 and 21 provided in the presser plate 19, respectively, and then through through holes 24 and 25 provided in the flat blade 5, Finally, the presser bolts 17 and 1 are screwed into the female threaded holes 22 and 23 provided on the front part of the slide bar 1 to secure the presser bolts.
8 to fix the flat blade 5.

This state is shown in FIG.

A state in which the tubular blade 4 is thus attached to the front portion of the holder 2 and the flat blade 5 is attached to the front portion of the sliding rod 1 is shown in FIGS. 3 and 4.

A groove-shaped flat blade guide portion 12 is provided at the portion where both side edges of the flat blade 5 touch the thickened fixed portion 6 of the tubular blade 4.
An elongated bow-shaped guide portion 13 is formed at the thin end portion of the tubular blade 4 (see FIGS. 12, 14, and 15).

Therefore, when the sliding rod 1 is moved forward, the flat blade 5 is guided by the groove-shaped flat blade guiding part 12 in the thick fixed part 6 of the tubular blade 4, and further forward, the flat blade 5 moves forward. The tip advances along a curved and elongated bow-shaped guiding part 13 formed at the tip of the tubular blade, and curves in a semicircle.

Since the corner of the flat cutting edge 5 is recessed as shown in FIGS. 10 and 11, the cutting edge of the flat cutting edge 5 reaches the bottom surface of the tubular blade 4.

Since the flat blade 5 is thus curved toward the bottom surface of the tubular blade 4, it is preferable that it is made of spring steel with excellent elasticity and restorability, and that the tip is provided with a curvature that makes it easy to curve.

Furthermore, the tip of the curved and elongated bow-shaped guide portion 13 may be bent further inward.

When using the collector of the present invention constructed in this manner, when applying force to the tissue section to be resected with the tip of the collector, the tubular blade 4 makes an incision in the tissue, and the tip of the holder 2 The surface acts as a stopper and stops.

Next, when the sliding rod 1 is moved forward, the flat blade 5 moves forward and curves as described above to cut out a quarter circle of tissue.

To give an example of the size of the tubular blade 4, the width of the bottom surface is 4 mm and the height is 3.5 mm.

The length to the stopper is 5 mm in the one shown in FIG.

With this collector, the length to the stopper can be changed as appropriate.

That is, to explain using the diagram shown in FIG. 4, the split pins 10 and 11 are removed, the tubular blade 4 is shifted to the right in the figure, and the position of the split pin insertion hole 8 in the fixing part 6 is provided in the front part 3 of the holder 2. (In this way, the position of the split pin insertion hole 8' provided in the fixing part 6 matches the position of the through hole 15' provided in the holder 2), The tubular blade 4 is fixed by inserting split pins 10 and 11, respectively.

In this case, the distance between the tip of the tubular blade 5 and the stopper is 4 mm.

Similarly, if the positions of the split pin insertion holes 9 and 9' are aligned with the positions of the through holes 16 and 16', respectively, and fixed with split pins, the distance to the stopper will be 3 mm.

In this way, the depth of excision of the living tissue can be changed as desired.

In FIGS. 1 and 2, reference numeral 26 denotes a surface for pushing the sliding rod 1 during the operation of collecting a biological tissue specimen, and 27 is a part into which a finger is inserted to hold the holder 2 by hand during the collection operation.

What has been explained above and shown in the drawings is related to typical examples to aid understanding of the present invention, and the present invention is not limited to these examples, but may include other changes and modifications within the gist of the invention. An example can be taken.

For example, in the drawings, the tubular blade 4 has a U-shaped cross section, but it may also have a triangular or semicircular shape on the right side of the U-shape.

In this case, the tip of the flat blade 5 must also match this shape.

As described above, the collector of the present invention has the following effects.

(1) According to the harvester of the present invention, there is almost no difference in technique when resecting living tissue, and even an unskilled person can easily and reliably harvest tissue at a predetermined depth.

(2) Easily change the resection depth of living tissue to a desired value;
Can be adjusted.

(3) The collected specimen will not be crushed, making it extremely desirable as a diagnostic specimen.

(4) With the conventional type, when the blade becomes no longer sharp, the entire collector must be sent for sharpening, and a spare one is therefore required.

In the collector of the present invention, both the tubular blade and the flat blade can be easily attached to and removed from the main body, so it is only necessary to sharpen only the blade part, and therefore only the blade part needs to be kept as a spare.

[Brief explanation of drawings]

Fig. 1 is a plan view of an example of the collector of the present invention, Fig. 2 is a side view of the same, Fig. 3 is a side view of the front part (left part in Fig. 1) of the device shown in Fig. 1, and Fig. 4. 3 is a plan view of the portion shown in FIG. 3, FIG. 5 is a perspective view of the front portion shown in FIG. 3 with the tubular blade and flat blade removed, and FIG. 6 is the collector shown in FIG. 1. 7 is a plan view of the portion shown in FIG. 6, and FIG. 8 is a side view of the front part of the holder that constitutes the
9 is a side view of the front portion of the sliding rod constituting the collector shown in FIG. 1, and is also an explanatory view showing how to attach the flat blade to this portion. Figure 10 is a plan view of the flat blade used in the collector shown in Figure 1, and Figure 11 shows the flat blade attached to the front part of the sliding rod of the collector shown in Figure 1. A schematic perspective view, FIG. 12 is a side view of the tubular blade used in the collector shown in FIG. 1, FIG. 13 is a plan view, FIG. 14 is a perspective view, and FIG. FIG. 16 is a schematic perspective view of the tip of the collector shown in FIG. 1; In the figure, 1 is a sliding rod, 2 is a rod-shaped holder that holds the sliding rod 1 so that it can move forward and backward, 3 is the front part of the holder, and 4 is a tubular shape with a part missing in the axial direction. 7.7', 8. a blade, 5 a flat flexible blade; 6 integral with the blade 4; a fixing part for fixing the blade 4 to the front part of the holder 2; B', 9 and 9' are split pin insertion holes for fixing the blade 4 to the front part of the holder, 10 and 11 are split pins, and 12 is a groove-shaped blade 5 formed in the fixing part 6 of the blade 4. 13 is a guide portion of the elongated curved thank-you letter blade 5 formed on the blade 4, 14°14
', 15, 15', 16 and 16' are through holes for split pins provided in the front part of the holder 2, 17 and 18 are presser bolts, 19 is a presser plate for the blade 5, and 20 and 21 are presser plates 19
through-holes for presser bolts 17 and 18 provided in 2;
2 and 23 are female screw holes for fixing the presser bolts 17 and 18;
Reference numerals 24 and 25 are holes through which presser bolts provided on the blade 5 are passed.

Claims (1)

[Claims] 1. Consists of an elongated sliding rod and a rod-shaped holder that holds the sliding rod so that it can move back and forth in the axial direction. A blade with a missing shape (hereinafter referred to as a tubular blade) is provided at the front part of the sliding rod, and a flat flexible blade (hereinafter referred to as a flat blade) is provided at a position covering the partially missing part of the tubular blade. As the sliding rod moves forward, the flat blade advances to cover the partially missing part of the tubular blade, and when it reaches the tip of the tubular blade, the tip of the flat blade closes the opening of the tubular blade. A living tissue collector 2 provided with a guiding portion of a flat blade that moves forward while being curved so as to close its tip.The living tissue collecting device according to claim 1, wherein the tubular blade has a U-shaped cross section. Device 3: A biological tissue collector according to claim 1, in which the tubular blade is detachably attached to the front part of the holder. The living tissue sampler 5 according to claim 3, which is configured to be detachably attached to two or more places. Biological tissue sampler