JPS6031263B2 - Reagent addition position switching device in clinical automated chemistry analyzer - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a reagent addition layer switching device in an automatic clinical chemistry analyzer, and particularly to a device for arbitrarily setting the timing of adding a second reagent.

Generally, in a clinical automated chemical analyzer, it is necessary to inject a substance into a reaction tube and then inject a reagent into the reaction tube.

Usually, one type of reagent is sufficient in some cases, but depending on the measurement item, it is necessary to inject a second reagent or even a third reagent.
In addition, the second and third reagents must be injected after a predetermined period of time has elapsed from the time of injecting the first reagent, and the timing of injecting the second and third reagents may vary depending on the measurement item. Therefore, it is necessary to change the injection point depending on the measurement item. Conventional automated chemical analyzers include a vertically arranged cylindrical body with a rotating body that rotates around its axis, and a plurality of reaction tubes arranged and fixed in a ring shape around the central axis of the rotating body. , the rotating body is rotated intermittently so that the reaction tube is fed sequentially for each operation step,
A rotating rotor having a rotor that has a flow path that passes through each of these reaction tubes and rotates together with the rotating body, and a stator that has several thin flow paths that are connected to the flow path at the joint surface of the rotor. There is an apparatus that includes a valve, and each passage of the stator of the rotary valve is connected to a sample injection part, a first reagent source, a second reagent source, an air injection part, etc., respectively.

According to this device, the second reagent injection position, the damaged air supply V
Since the feed position is fixed and it is extremely difficult to change it, and the rotating body is rotated intermittently at regular intervals, it is difficult to measure different measurement items. Nevertheless, the time interval between the first reagent and the second reagent will be fixed.

Therefore, there is a drawback that it is not possible to perform an appropriate reaction according to the measurement item. The purpose of this invention is to eliminate the above-mentioned drawbacks, and it is possible to arbitrarily change the injection position of the second reagent and to arbitrarily select the injection point of the second reagent according to the measurement item after injection of the first reagent. The present invention provides a device that provides

The present invention will be explained in detail below based on the drawings.

FIG. 1 will be explained. A rotating member 14 is rotatably held on the cylindrical body 12 to which the base 10' is fixed, and a plate 16 is fixed to this rotating member 14. A plurality of reaction measurement tubes 20 are arranged on the lower annular receiving portion 18 of the rotation member 14 in a ring shape around the rotation axis of the rotation member, and the upper portions of these reaction measurement tubes are held down by the plate body 16. . These reaction measuring tubes are made of transparent material and have funnel-shaped bottoms. Rotors 2 of rotary valves 22 and 24 are installed at the upper and lower parts of the rotating body 14, respectively.
6 and 28 are fixed.

These rotors are provided with channels 30 and 32 that communicate with each reaction measuring tube 20, respectively, and each channel closes at the joint surface. The rotor 26 is connected to a fixed stator 38 via a base 1 side flange member 36 at its joint surface. The stator 38 includes a gas or liquid discharge pipe 40,
A flow path 44 communicating with 42 is provided. Rotor 28
An operation rotor 46 is connected to the operation rotor 46, and a drive plate 48 is fixed to this operation rotor, and this drive plate is rotated by a predetermined angle by a Geneva mechanism 52 operated by a motor 50. A stator 54 is further joined to the operating rotor 46 . The stator 54 is fixed to a holder 56 that is held in the cylindrical body 12 so that it can move in all directions of its axis but not rotate, and has a flow path 60 that communicates with the sample injection tube, the cleaning liquid supply tube, or the 9E liquid tube 58. ing. Figure 2 is A- in Figure 1.
This is a diagram showing cross section A, where the operating rotor 46 is the rotor 28.
a flow path 62 that corresponds to each of the flow paths 32 on the joint surface and is provided parallel to the axis of rotation, and a flow path 6 that allows the second reagent supply pipe 64 to pass through any one of the narrow paths 32 of the rotor 28.
6, and a damage air supply pipe 6 installed adjacent to this flow path.
8 and a flow path 70 extending through it.

The rotor, stator, rotating body, etc. of each valve are pressed against the flange member 36 by a disc spring 72. Light from the light source 74 is incident on the mirror 80 via the lens 76 and the filter 78, and passes through the through holes 82 provided in the rotating member 14 in the radial direction corresponding to each reaction measurement tube 201 and the reaction measurement tube 20 to the photoelectric element. 84 to perform colorimetric measurement of the reaction solution in the tube 20.

As explained above, according to the present invention, the operating roller 4
6, the injection position of the second reagent and the boundary air introduction position provided adjacent to the second reagent injection passage can be adjusted based on the fact that dehydration is required immediately after injecting the second reagent. Since they can be selected and set arbitrarily as a pair at the same time, it is extremely easy to set the second reagent injection time depending on the difference in measurement items.

Note that setting of the third reagent is possible by providing yet another operating rotor (not shown) for the third reagent.

[Brief explanation of the drawing]

FIG. 1 is an explanatory longitudinal sectional view showing an embodiment of the present invention, and FIG. 2 is a sectional view taken along A--A in FIG. 12... Cylindrical body, 14... Rotating member, 20
...Reaction measurement tube, 23, 24 ... Rotating valve, 26, 28 ... Rotor, 38, 54 ... Stator, 46 ... Operation rotor, 64 ... -Second reagent supply pipe, 68...Air supply pipe. Figure 1 Figure 2

Claims (1)

[Claims] 1. A vertically disposed member fixed to a base, a rotating member rotatably supported on the member so as to be rotatable around its central axis, and a plurality of members disposed on the rotating member in a circular manner about the central axis. a reaction measurement tube, a mechanism for rotating the rotating member intermittently at a predetermined angle, and a rotor that rotates together with the rotating member and has a plurality of channels that communicate with each of the reaction measurement tubes and open to a joint surface. , a stator fixed to the vertically disposed member or the base body and having a plurality of flow passages that communicate with a required liquid supply source or a liquid discharge part and open to a joint surface; In order to communicate the flow path of the rotor with the flow path of the stator, a flow path is provided that opens on both joint surfaces so as to face the opening of the joint surfaces of the rotor and the stator, and the axis of the vertically disposed member is and an operating rotor that can rotate around the center, and the operating rotor is provided with a reagent flow path that opens at a joint surface that joins with the joint surface of the rotor and that communicates with the reagent supply source without passing through the stator. A reagent addition position switching device for a clinical automated chemical analyzer, characterized in that a reagent supply position can be arbitrarily selected by rotating the operation rotor.