JPS6123766B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to a dentifrice composition suitable for removing cigarette tar stuck to teeth, dentures, etc. Denture cleaners containing strong alkali as a main ingredient have been commercially available for the purpose of removing cigarette tar and dental plaque. Further, compositions containing organic acids such as citric acid, tartaric acid, malic acid, and their salts in combination have also been found to be effective in removing tar under strongly acidic conditions. Although these strongly alkaline or strongly acidic cleaning agents and compositions can be used to remove stains from dentures, there are problems in using them directly on natural teeth. A method of polishing and removing tar deposited on the teeth has been carried out using a dentifrice containing a dentifrice. However, with this method, it is difficult to completely remove the tar adhered to the teeth, and problems such as scratching and abrasion of the teeth may occur. The present inventors have conducted various studies to solve the above problems, and have found that phytic acid and its derivatives are extremely effective in removing cigarette tar stuck to teeth in a wide PH range including the neutral range. When the above-mentioned phytic acid and its derivatives coexist with polyvalent metal ions such as calcium ions and magnesium ions, the tar removal effect is greatly reduced. It was discovered that the tar removal effect could not be expected even if it was added to toothpaste containing phytic acid and its derivatives, and as a result of further research on these points, it was found that citric acid, citric acid,
When a predetermined amount of an organic acid selected from tartaric acid, malic acid, and fumaric acid or its salt is blended, it exhibits a strong tar removal effect even when polyvalent metal ions such as calcium ions, magnesium ions, and aluminum ions coexist. The present invention was completed based on this finding, and an object of the present invention is to provide a dentifrice composition containing a base that releases polyvalent metals, in which phytic acid or its derivatives are combined with citric acid, tartaric acid, and apple. By blending an organic acid selected from acid and fumaric acid or its salts,
An object of the present invention is to provide a toothpaste composition that is highly effective in removing tobacco tar. The present invention will be explained in detail below. The phytic acid used in the present invention is a hexaphosphoric acid ester of myo-inositol, and the phytic acid derivatives are those in which some or all of the hydrogen atoms of the phosphoric acid groups at positions 1 to 6 of phytic acid are replaced with an alkali metal. Alkali metal salts and ammonium salts of phytic acid such as sodium phytate and potassium phytate, as well as hydrogen atoms in some or all of the phosphoric acid groups at positions 1 to 6 of phytic acid replaced with alkyl groups, allyl groups, etc. things etc. can be used. The amount of these phytic acid and phytic acid derivatives is 0.1 to 50% by weight (hereinafter simply expressed as %) in terms of phytic acid based on the total weight of the dentifrice composition, especially 1%.
~20% is preferred. When the amount of phytic acid and phytic acid derivatives is less than 0.1%, the swelling effect of tar is insufficient, and it takes a long time to completely remove tar from the teeth. Organic acids include citric acid, tartaric acid, malic acid,
One or more types of fumaric acid can be used, and their alkali metal salts, ammonium salts, etc. can also be used. In this case, salts of organic acids, particularly sodium citrate, are particularly preferred since they also have the effect of softening the soapy taste of sodium phytate. The amount of organic acids and their salts is preferably 0.1 to 20% based on the total weight of the dentifrice. When the amount of organic acids and their salts is less than 0.1%, the time required to remove tar becomes longer. In addition, the polyvalent metal-releasing base (abrasive) used in the present invention is known, such as dibasic calcium phosphate dihydrate, dibasic calcium phosphate dihydrate, etc.
Anhydrous salts, tricalcium phosphate, calcium carbonate, calcium sulfate, aluminum hydroxide, calcium pyrophosphate, magnesium oxide, magnesium carbonate, magnesium silicate, etc. can be used, and the blending amount is usually 5 to 70% of the total weight of the dentifrice, especially Ten
~60% is preferred. Furthermore, non-polyvalent metal abrasives such as insoluble sodium metaphosphate, anhydrous silicic acid, and plastic powder may be blended with these. Other components of the present invention are the same as those of conventional dentifrice compositions, and various known components such as the following may be blended. Namely, thickeners such as glycerin, sorbitol, propylene glycol, and polyethylene glycol, binders such as sodium carboxymethyl cellulose, carrageenan, sodium alginate, and vegum, sweeteners such as sodium saccharin, glycyrrhizic acid, and stevioside, silicic anhydride, etc. non-abrasive inorganic powder, anionic activators such as sodium lauryl sulfate, olefin sulfonate, acyl sarcosinate, monoglysulfonate soap, sodium lauroyl sarcosine, stearic acid monoglyceride, lauryl diethanolamide, sucrose fatty acid ester, etc. Foaming agents such as nonionic activators and amphoteric activators, fluorides such as sodium fluoride, sodium monofluorophosphate, and tin fluoride, disinfectants such as chlorhexidine hydrochloride, enzymes such as dextranase and amylase, and epsilon aminocapron. Active ingredients such as acid, anti-inflammatory agents such as allantoin and tranexamic acid, fragrances such as l-menthol, l-carvone and anethole,
Furthermore, water and the like are selected depending on the properties of the dentifrice product, and the dentifrice composition is produced by a conventional method. For example, phytic acid is strongly acidic, and a toothpaste composition containing it will exhibit strong acidity, but by incorporating a PH regulator, it can be adjusted to any desired PH value without reducing the tar removal effect. be able to. As the PH adjuster, for example, organic acids such as acetic acid, citric acid, tartaric acid, malic acid, malonic acid, fumaric acid, and their alkali metal salts or ammonium salts can be used, as well as phosphoric acid,
There are inorganic acids such as hydrochloric acid, alkali metal hydroxides such as sodium hydroxide and potassium hydroxide, and alkalis such as ammonia, and these can be used alone or in an appropriate combination to adjust the desired pH value. The dentifrice composition of the present invention is used in a normal manner, and in this case, although the aqueous solution of phytic acid or its derivatives itself does not have a sufficient action of dissolving tar, the aqueous solution does not allow tar to stick to the solution. When a tooth is immersed, it is observed that the tar swells on the tooth surface and floats up like a resin, and when this is gently wiped, the tar detaches from the tooth surface, indicating that the aqueous solution of phytic acid and its derivatives is strongly resin-like. It has the effect of breaking down the resin structure of tar, and therefore tar can be removed satisfactorily by polishing teeth with the tooth brushing composition. As described above, the dentifrice composition according to the present invention has a compounding effect of phytic acid and its derivatives, which exhibits a tar removal effect in a wide PH range including the neutral range.
The PH value of the dentifrice composition can be set around normal neutrality, and therefore it is suitable as a dentifrice. Furthermore, the dentifrice composition of the present invention contains dibasic calcium phosphate dihydrate, which releases polyvalent metal ions such as calcium ions, magnesium ions, and aluminum ions, by blending an organic acid such as citric acid.
Even in the presence of a base (abrasive) such as calcium carbonate, magnesium oxide, or aluminum hydroxide, phytic acid or its derivatives have a remarkable swelling effect on tar, and when combined with the action of the abrasive, it has an extremely high tar removal effect. It is something that you have. In this case, products that do not contain these organic acids do not have a sufficient tar removal effect as described above, and cannot achieve the object of the present invention. Further, the abrasive can be freely selected to have an appropriate abrasive power that does not cause scratches or wear on the teeth. Note that phytic acid is extracted and separated from grains, and the PH value can be brought to around neutrality, so the present toothpaste composition is highly safe. Next, the present invention will be explained in more detail using experimental examples. [Experimental Example] A test sample having the composition shown in the table below was prepared by mixing phytic acid, an organic acid salt, and an abrasive. These test samples were then used to brush teeth twice a day for 30 days and their tar-removing effectiveness was evaluated. (Panel: 3 smokers who are prone to tar adhesion) Criteria for evaluation: The teeth were photographed and evaluated by observation. ++ Most of the tar was removed. + A large amount of tar was removed. ± Tar was slightly removed. - Almost no tar has been removed.

〔Example〕

A toothpaste was manufactured by blending each component of the composition shown in the table below according to a conventional method. 50% phytic acid aqueous solution 5.7 25% sodium hydroxide aqueous solution 5.1 Sodium citrate (dihydrate) 2.8 Dicalcium phosphate 40.0 Amorphous silica 3.0 Sorbitous 16.0 Sodium lauryl sulfate 2.0 Carboxymethyl cellulose 1.0 Satucalin 0.1 Flavor 1.0 Water Remaining total 100.0 ( %) This dentifrice was highly effective in removing stains and gave a refreshing feeling without the soapy taste of phytic acid.

Claims (1)

[Scope of Claims] 1. A dentifrice composition comprising a base that releases polyvalent cations, phytic acid or a derivative thereof;
A dentifrice composition comprising an organic acid selected from citric acid, tartaric acid, malic acid, and fumaric acid or a salt thereof. 2. The dentifrice composition according to claim 1, wherein the phytic acid equivalent content of phytic acid or its derivative is 0.1 to 50% by weight based on the total weight.