JPS6127367B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to skin coloring compositions, more specifically,
This invention relates to a skin coloring composition used to change unhealthy pale skin to healthy, moderately tanned, so-called wheat-colored skin.

Conventionally, compositions containing dihydroxyacetone as a main component have been known as such skin coloring compositions, and are commercially available, for example, under trade names such as "Bronzer." It is thought that the composition produces coloration by binding to skin proteins through the so-called Mayer reaction (amino-carbonyl reaction), and in order to obtain an appropriate coloration of the skin in a relatively short time, it is necessary to irradiate it with infrared rays or the like. It is necessary to raise the temperature.

The present inventors have surprisingly found that when using a metabolite of dopa, dopamine, noradrenaline and/or adrenaline, which is an in vivo component, and a ferrous salt, unlike a conventional composition mainly composed of dihydroxyacetone, The present invention was completed based on the knowledge that appropriate skin coloration can be easily obtained at room temperature in a short time without the need for irradiation with infrared rays or the like.

That is, the present invention provides 3,4-dihydroxyphenylpyruvic acid, 3,4-dihydroxyphenylacetic acid, 3,4-dihydroxyphenylethanol, 3,4-dihydroxymandelic acid, 3,4-
The present invention provides a skin coloring composition containing one or more compounds selected from dihydroxyphenylethylene glycol and a ferrous salt. The skin coloring composition of the present invention has a coloring mechanism for the skin that differs from conventional compositions containing dihydroxyacetone as a main component, in that ferrous salt is first adsorbed to skin proteins, and then oxidized by air etc. Therefore, it is assumed that the divalent iron changes to trivalent iron, which combines with the above-mentioned metabolites to produce a moderate coloring on the skin. It is thought that it is possible to easily color the skin in a short time at room temperature without using it. In addition,
The composition of the present invention may be a so-called two-part type composition in which the composition containing the ferrous salt is the first part and the composition containing the metabolite is the second part. After treating the skin, using the second solution,
Coloring can be done more easily.

The metabolites used may be used alone or in combination of two or more, and the amount to be added can be selected as appropriate depending on the desired formulation, but from the viewpoint of solubility and combination effect,
The range is preferably 0.01 to 10% based on the total weight of the composition (in the case of a two-part type, the weight of the second part).

Examples of the ferrous salts used include ferrous sulfate, ferrous chloride, ferrous perchlorate, ferrous phosphate, and ferrous oxalate, which may be used alone or in combination of two or more. You may. From the viewpoint of coloring effect, it is preferable to use 0.01 to 2 parts by weight per 1 part by weight of the metabolite.

The skin coloring composition of the present invention can be in various dosage forms such as lotions, creams, and emulsions. , can be produced by conventional methods such as emulsification.

Next, the present invention will be explained in more detail with reference to Examples, but the present invention is not limited thereto.

Example 1 Lotion formula ingredients Weight % Ferrous sulfate 0.3 3,4-dihydroxymandelic acid 0.2 Sorbitol 5.0 Polyoxyethylene castor oil derivative 0.5 Citric acid 0.1 Sodium citrate 0.1 Methyl benzoate 0.1 Fragrance Appropriate amount Ethanol 12.0 Purified Water Adjust to 100% According to this recipe, obtain a lotion using the usual method. Take an appropriate amount of this lotion on a makeup cotton and apply it lightly to the entire face. After 5 to 10 minutes, the color will gradually change.
The skin has a moderate tan color.

Example 2 Cream formulation Ingredient A Weight% Stearic acid 15.0 Setanol 0.5 Vaseline 5.0 Isopropyl myristate 4.0 Butyl benzoate 0.1 Ingredient B Weight% Triethanolamine 0.7 Maltitol 2.0 Propylene glycol 3.0 Methyl benzoate 0.1 Ferrous sulfate 0.5 3.4 -Dihydroxymandelic acid 0.4 L-Ascorbic acid 0.3 Purified water Prepared to 100% C component fragrance Appropriate amount After heating and dissolving components A and B at 80°C, add component A to component B with stirring, then add component A to component B while stirring. , homogenize for approximately 5 minutes. Stir while cooling;
Add component C at 60°C, and further cool and stir to 35°C to obtain cream. Take an appropriate amount of this cream on a sponge or sponge and apply it evenly and thinly on your face.
In minutes, the skin becomes a moderate tan color.

Example 3 Emulsion formulation A component Weight % Liquid paraffin 7.0 Lanolin 3.0 Oleic acid 3.0 Butyl benzoate 0.1 B component Weight % Triethanolamine 1.2 Methyl benzoate 0.1 Ferrous chloride 0.7 3,4-dihydroxyphenylacetic acid 0.6 Purified water 100 Adjust to % C component fragrance Appropriate amount After heating and dissolving components A and B at 80°C, add component A to component B and homogenize for about 5 minutes. Next, the mixture is stirred while cooling, component C is added at 60°C, and the mixture is further cooled and stirred to 35°C to obtain a milky lotion. Take an appropriate amount of this emulsion on a cosmetic cotton or sponge and apply it evenly and thinly to your face, and within 5 to 10 minutes your skin will be colored to a suitable tan color.

Example 4 Lotion prescription ingredients Weight % Ferrous sulfate 0.4 3,4-dihydroxyphenylpyruvic acid
0.2 Glycerin 6.0 Oleyl alcohol 0.1 Polyoxyethylene sorbitan monolaurate (20E.O.) 1.2 Polyoxyethylene lauryl ether (20E.O.) 0.7 Ethanol 12.0 Fragrance 0.1 Methyl benzoate 0.1 Purified water Adjusted to 100% This formula Obtain lotion by the usual method. Apply an appropriate amount of this lotion on a cotton pad and apply it lightly over the entire face. After 5 to 10 minutes, the skin will become gradually colored and the skin will take on a moderate tan color.

Example 5 Lotion formula ingredients Weight % Ferrous sulfate 0.05 3,4-dihydroxymandelic acid 0.2 3,4-dihydroxyphenyl Ethylene glycol 0.3 Glycerin 3.0 1,3-Butylene glycol 2.0 Polyethylene glycol 1000 1.0 Polyoxyethylene oleyl Ether (25E.O.) 1.5 Hydroxyethyl cellulose 0.2 Carrageenan 0.1 Ethanol 15.0 Fragrance 0.1 Methyl benzoate 0.2 EDTA-4Na 0.1 Purified water Adjusted to 100% According to this recipe, a lotion is obtained by a conventional method. Take an appropriate amount of this lotion on a cotton pad and apply it lightly over the entire face. After 5 to 10 minutes, the skin will gradually become colored and the skin will take on a moderate tan color.

Example 6 Cream formulation A ingredient Weight % Stearic acid 2.0 Stearyl alcohol 6.0 Deodorized lanolin 1.5 Squalane 5.5 Octyldodecanol 4.0 Polyoxyethylene cetyl ether (25E.O.) 3.0 Lipophilic glyceryl monostearate 1.8 Butyl benzoate 0.1 Dibutyl Hydroxytoluene 0.1 Component B Weight% Glycerin 6.0 Methyl benzoate 0.1 3,4-dihydroxyphenylethanol
0.5 Ferrous sulfate 0.005 Purified water Adjusted to 100% C component Weight% Fragrance 0.2 After heating and dissolving components A and B at 75℃,
Add component A to component B while stirring, then add about 5
Homogenize for minutes. Stir while cooling and heat to 60°C.
Add the ingredients and further cool and stir to 35°C to obtain cream. Take an appropriate amount of this cream on a sponge or sponge and apply it evenly and thinly to your face. Within 5 to 10 minutes, your skin will be colored to a moderate tan color.

Example 7 Emulsion formulation A component Weight % Squalane 3.0 Vaseline 2.0 Liquid paraffin 2.0 Beeswax 0.4 Sorbitan sesquioleate 0.8 Polyoxyethylene oleyl ether (20E.O.) 1.3 Butyl paraoxybenzoate 0.1 B component Weight % Ferrous sulfate 0.1 3,4-Dihydroxyphenyl Ethylene glycol 0.8 1,3-Butylene glycol 5.0 Methyl paraoxybenzoate 0.1 Purified water Adjusted to 100% C component Weight% Carboxyvinyl polymer (1.0% aqueous solution) 20.0 D component Weight% Potassium hydroxide (1 % aqueous solution) 10.0 Component E Weight % Ethanol 5.0 Fragrance 0.2 After heating and dissolving components A and B at 75°C,
Add component A to component B while stirring, then add about 5
Homogenize for minutes. Once the mixture was homogeneous, add component C and mix well, then add component D and mix for about 5 more minutes after neutralization.
Homogenize for minutes. Stir while cooling and heat to 60°C.
Add the ingredients and further cool and stir to 35°C to obtain a milky lotion. Take an appropriate amount of this emulsion on a sponge or sponge and apply it evenly and thinly to your face, and within 5 to 10 minutes your skin will be colored to a suitable tan color.

Claims (1)

[Claims] 1 3,4-dihydroxyphenylpyruvic acid,
Contains one or more compounds selected from 3,4-dihydroxyphenyl acetic acid, 3,4-dihydroxyphenylethanol, 3,4-dihydroxymandelic acid, and 3,4-dihydroxyphenylethylene glycol and ferrous salt. A skin coloring composition characterized by: 2. The skin coloring composition according to item 1 above, which contains 0.01 to 2 parts by weight of ferrous salt per 1 part by weight of the compound. 3. The skin coloring composition according to item 1 above, which is a two-part type, wherein the composition containing the ferrous salt is the first part, and the second part is the composition containing the compound.