JPS6139231B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a tube for filling semi-solid preparations such as ointments and creams.

Conventionally, as a filling tube for this type of semi-solid preparation, a cylindrical metal tube with a small-diameter threaded portion formed at one end so that a cap can be screwed in, and the other end closed by flattening the tube has been used. There is. However, such conventional filling tubes require complicated molding processes, and especially when the amount of drug to be filled is small, not only is the cost high, but also the filling operation is difficult. It was not suitable as a container for filling only the amount necessary for coating. In addition, applying semi-solid preparations directly to the fingers or having the opening of the filling tube come into direct contact with the affected area may result in dirty fingers and the risk of secondary infection, as well as contamination of the semi-solid preparations. There is a possibility that

This invention has been made in view of the above circumstances, and is a semi-solid preparation suitable for filling only the amount necessary for one application, and which can be applied easily and hygienically. The purpose of this invention is to provide a tube for filling pharmaceutical preparations.

That is, the present invention seals an upper sheet comprising a metal layer and a thermoplastic layer and a lower sheet comprising a metal layer and a thermoplastic layer together at an edge, and forms a dosing semi-solid material inside the edge. A container body having a formulation filling part formed therein, an opening provided at one end of the container body and communicating with the semi-solid formulation filling part, and a container body partially adhered to the container body so as to close the opening. The present invention provides a filling tube for filling a semi-solid drug for medication, comprising an opening piece and a pad made of a soft-touch material attached around the opening or on the inner surface of the opening piece. be.

Hereinafter, the present invention will be explained with reference to the illustrated embodiments. In the figure, 1 is the main body of the container, and sheets containing a metal layer and a thermoplastic layer, such as sheets laminated in the order of polyethylene, polyvinyl chloride, aluminum, and polyester, are used as the upper sheet 2 and the lower sheet 3, respectively. These are stacked on top of each other with the polyethylene layer inside and the edges 4 are heat-sealed to form a semi-solid preparation filling part 5 inside.

One end of this container body 1 is slightly tapered, and as shown in FIG. Conductive. An opening piece 8 made of, for example, a thermoplastic sheet is partially adhered to the upper sheet 2 to completely close the opening 7, and one end of the opening piece 8 is attached to the narrow width part 6, as shown in FIG. is folded back to the lower sheet 3 side and similarly partially adhered.
As shown in FIG. 2, the opening piece 8 adhered to the upper sheet 2 side is in a non-adhered state at its end.
It serves as a grip piece 9.

When filling a semi-solid preparation into this semi-solid preparation filling tube, leave the corresponding edge 4 on the side of the container body 1 opposite to the narrow width portion 6, and fill the other edge 4 with the other edge 4.
is completely sealed and the unsealing piece 8 is partially adhered, and then a predetermined semi-solid preparation is filled through this edge 4', and after filling is completed, only this edge 4' is heat-sealed. The sealed state of the semi-solid preparation can be maintained by sealing with a sealant or the like.
Note that the above-mentioned filling method is only an example, and it is of course possible to fill by other methods.

When using a tube filled with a semi-solid preparation in this way, as shown in Figure 3, the opening piece 8
Open the opening 7 by grasping the grip 9 with your fingers and pulling it in the direction of the arrow as shown in FIG. 3, then leave the opening piece 8 attached to the container body 1 without completely peeling it off. By keeping the container in this state and pressing the filling section 5, the semi-solid preparation can be pushed out through the opening 7. Next, this semi-solid preparation is applied to the required area, but in this case, if the peeled part of the opening piece 8 that has been partially peeled off is used as described above, the semi-solid preparation can be applied without staining the fingers. Semi-solid preparations can be applied hygienically and without contaminating the skin.

FIG. 4 shows another embodiment of the present invention, and in the embodiment shown in FIGS. 1 to 3 described above,
This embodiment is the same as the previous embodiment except that an annular pad 10 is further bonded around the opening 7. This pad 10 provides a buffering effect to soften the touch with the affected area when applying the filler preparation, thereby making the application operation easier and sanitary. The pad 10 is selected from a material that provides a soft feel, such as rayon, or a nonwoven fabric made of synthetic fibers such as polyester or nylon.

When compared with the embodiment shown in FIGS. 1 to 3, the embodiment shown in FIG. It is characterized by two points: a pad made of the same material as that described above is glued to it. That is, in this embodiment, instead of using the upper sheet 2 having an opening at the end as in the previous embodiment, the upper sheet 2 and the lower sheet 3, which do not have such an opening, are overlapped and the edges are 4 (for example, part of the narrow part 6)
The entire other edge is sealed, leaving a . Therefore, this non-sealed part 11 has an opening 12 formed at its end, which communicates with the inside of the drug filling part 5 of the container body 1, and the opening 12.
The filled formulation can be squeezed out through the .

On the other hand, a pad 13 of an appropriate size, for example a square shape, is adhered to the inner surface of the opening piece 8 that comes into contact with the upper sheet. Therefore, when the filled preparation is squeezed out with the opening piece 8 peeled off as shown in FIG.
Since the preparation is released onto this pad 13, the preparation can be hygienically applied to the affected area using this pad 13 without causing any damage to the affected area.

In addition, as other modifications corresponding to the embodiment shown in FIG. 5, pad 13 may be omitted, pad 1
3 may be adhered to the upper surface of the upper sheet 2 near the opening 12.

The filling tube for semi-solid preparations according to the present invention has many advantages compared to conventional cylindrical metal tubes. For example, it is very easy to fill a minute amount of a preparation, such as a single application amount. Therefore, the dosing schedule for semi-solid preparations, which has been difficult in the past, becomes easy, and there is no risk of secondary contamination as in the case of conventional cylindrical metal tubes that are used repeatedly. The manufacturing cost is low because the structure is simple. It is easy to open, and the filled preparation can be rubbed using the opening piece or pad, so it is hygienic and does not stain fingers.

Note that the material of the upper sheet and lower sheet forming the container body 1 is not limited to the four-layered material as in the above embodiment, but the number of laminated layers may be smaller or larger depending on the properties of the filling material. do not have. The material can be selected as appropriate, such as one with good corrosion resistance and gas barrier properties to keep the filling stable over time, and one with appropriate hardness to make it easier to extrude the filling. . When laminating and heat-sealing multiple plastics, select materials with relatively low melting points such as unoriented polypropylene, polyethylene, polystyrene, and ionomer resins for the inner layer, and select high-density polyethylene, ionomer resin, etc. for the outer layer. It is preferable to appropriately use materials having a higher melting point than the inner layer, such as oriented polypropylene, polyvinyl chloride, polystyrene, polycarbonate, polyvinylidene chloride, nylon, and cellophane.

The opening piece may be made of a material that is airtight enough to prevent the filling from leaking and is flexible enough to be rubbed, such as polyvinyl chloride, polyethylene, polyester, ethylene/vinyl acetate copolymer, A laminated film based on polypropylene or these synthetic resins, and a nonwoven fabric such as rayon, polyester, or nylon laminated inside the synthetic resin may be used.

This opening piece may be adhered to the upper sheet or the like constituting the container body before the filling tube is formed, or conversely, it may be adhered after the filling tube is formed.

[Brief explanation of the drawing]

FIG. 1 is a plan view of a tube for filling semi-solid preparations according to the present invention, FIG. 2 is a side view thereof, and FIG. 3 is a plan view showing an aspect of the filling tube shown in FIG. 1 with the opening piece peeled off. FIG. 4 is a plan view showing the main parts of a tube for filling semi-solid preparations according to another embodiment of the present invention, and FIG. 5 shows the main parts of a tube for filling semi-solid preparations according to another embodiment of the present invention. FIG. In the figure, 1...container body, 2...upper sheet, 3
... lower sheet, 4 ... edge, 5 ... filling part, 6
... Narrow width part, 7 ... Opening part, 8 ... Opening piece, 9 ...
...Gripping portion, 10...Padded, 11...Non-sealed portion, 12...Opening, 13...Padded.

Claims (1)

[Scope of Claims] 1. An upper sheet comprising a metal layer and a thermoplastic layer and a lower sheet comprising a metal layer and a thermoplastic layer are sealed to each other at an edge, and a dispensing device is provided inside the edge. a container body forming a semi-solid preparation filling part; an opening provided at one end of the container body and communicating with the semi-solid preparation filling part; a part formed in the container body so as to close the opening; 1. A tube for filling a semi-solid drug for medication, comprising: an opening piece adhered to the opening piece; and a pad made of a soft-touch material attached around the opening or on the inner surface of the opening piece. 2. The filling tube according to claim 1, wherein the opening is formed in the upper sheet. 3. The filling tube according to claim 1, wherein the opening is formed between the upper sheet and the lower sheet.