JPS6154370B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to a pet collar, and more particularly to a pet collar that can be worn on fur-bearing pets such as dogs and cats to exterminate fleas and ticks that live in the pet's fur. Conventionally, pet collars that have the effect of exterminating fleas and ticks have been made using DDVP, or O,O-dimethyl O-(2,2-dichloro), which is volatile at room temperature.
It is known that vinyl phosphate is used as the main insecticide, and this is kneaded into vinyl chloride resin and molded. However, the DDVP used in this collar not only has the effect of inhibiting cholinesterase in pets, but also has the risk of causing dermatitis in pets, and is also harmful to children and others who often come into direct contact with pets. , which was extremely dangerous in practice. The present inventors have conducted various studies with the aim of providing a collar using a safer insecticide instead of the above-mentioned known pet collars. However, almost all insecticides conventionally known to be safer than DDVP are non-volatile at room temperature, and when mixed into resin like DDVP, they could not actually exhibit any insecticidal effect. Moreover, some of these insecticides decompose during kneading and molding, losing their effects, and it is difficult to knead them uniformly. In addition, in a series of studies using the above-mentioned highly safe non-volatile insecticides at room temperature, the insecticides were applied to ordinary synthetic leather and various natural or synthetic resin base materials for pet collars. It was confirmed that the collar thus obtained has approximately the same insecticidal effect against pests that come into direct contact with the collar as compared to the collar using known DDVP. However, in reality, it is extremely rare for pest insects such as fleas that live in the pet's body fur to come into direct contact with the above-mentioned collar, and when the above-mentioned collar is actually worn on a pet, it has an insecticidal effect on the entire pet's body. I couldn't have expected it at all. However, in subsequent research, the present inventors used a raised base material with naps of a specific height, which had never been used as a base material for a collar band of this type, and coated it with an insecticide that is non-volatile at room temperature. The collar obtained by the above method exhibits an excellent insecticidal effect, and surprisingly, when the collar is worn on a pet, it kills insects throughout the pet's body, even though the insecticide is non-volatile at room temperature. It was found that the effect was recognized. The present invention was completed based on the discovery of this new fact. That is, the present invention relates to a pet collar comprising a raised base material having a raised height of 2 to 15 mm and holding an insecticide that is nonvolatile at room temperature. The most important feature of the pet collar of the present invention is that it can exhibit an excellent insecticidal effect. This insecticidal effect is particularly observed throughout the pet's body.
Furthermore, since a highly safe insecticide can be used, its use is safe, and there is no risk of causing dermatitis in pets or cholinesterase inhibition, as seen with known collars using DDVP. In the present invention, as the raised base material, materials having various kinds of raised materials can be used. The material may be synthetic fiber, animal fiber, vegetable fiber, or inorganic fiber, and specifically, polypropylene, nylon, polyester, polyethylene, pig hair, silk thread, wool, raccoon hair, fluff, cellulose, hemp,
Examples include glass wool and asbestos. The height (length) of the nap needs to be 2 to 15 mm, although it varies slightly depending on the size of the target pest, the hardness of the nap, the diameter, etc. Outside this range, the insecticidal effect, especially the insecticidal effect on the pet's body in general, decreases. In addition, the diameter, density, condition, etc. of the nap can be selected as appropriate, and the diameter is usually about 10 μ to 1 mm, and the density is 20 to 4000 pieces/cm ²
It is preferable to set it as approximately. Although the manufacturing method thereof is arbitrary, it is preferable to use, for example, flocking. As long as the insecticide used in the present invention is nonvolatile at room temperature, various agents conventionally used for the purpose of exterminating pests can be used. The following are examples of typical drugs. (1) Pyrethroid insecticide Γ 3-allyl-2-methylcyclopentane-2-
En-4-one-1-yl chrysanthemate (generic name allethrin) Γ N-(3,4,5,6-tetrahydrophthalimide)-methyl chrysanthemate (generic name phthalthrin) Γ 5-benzyl-3-furyl Methyl chrysanthemate (generic name: resmethrin) Γ 5-propargyl-3-furylmethyl chrysanthemate (generic name: furamethrin) Γ 2-methyl-5-propargyl-3-furylmethyl chrysanthemate (generic name: proparsulin) Γ 3-Phenoxybenzyl d-cis/trans-chrysanthemate (generic name phenothrin) Γ 3-phenoxybenzyl 2,2-dimethyl-3-(β,β-dichlorovinyl)cyclopropane-carboxylate (general name Γ (R,S)-α-cyano-3-phenoxybenzyl (R,S)-2-(4-chlorophenyl)-3-methylbutyrate (generic name Fuenvalerate) Γ (R, S)-α-cyano-3-phenoxybenzyl 2,2,3,3-tetramethylcyclopropanecarboxylate and their steric and optical isomers Γ Optical isomers of allethrin (trade name Pinamin Forte; Sumitomo Chemical Co., Ltd. Γ Stereo-optical isomers of allethrin (product name: Exrin; manufactured by Sumitomo Chemical Co., Ltd., product name: Bioallethrin; manufactured by Roussel-Uclaf) Γ Optical isomers of resmethrin (product name: Chrysronforte; manufactured by Sumitomo Chemical Co., Ltd.) (manufactured by Kogyo Co., Ltd.) (2) Organophosphorus insecticide Γ O,O-dimethyl O-(3-methyl-4-
(3) Carbamate insecticides Γ 1-naphthyl N-methyl carbamate (common name Carbaryl) Γ o-isopropoxyphenyl N-methyl carbamate (common name Propoxar) The above insecticides These agents can be used alone or in combination of two or more. Furthermore, various additives that are usually added to this type of insecticide can be added to the insecticide. Typical additives include piperonyl butoxide, N-propylisome, and S-
Examples include potency enhancers such as 421, MGK-264, Cinepirin 222, and Cinepirin 500, deodorants such as lauric acid methacrylate, fragrances such as citral and citronellal, and thickeners such as silicic anhydride. The above-mentioned insecticide can be retained on the substrate by any method as long as the insecticide is adhered to and retained on the substrate. For example, the insecticide can be sprayed directly onto the substrate in powder form, but it is usually preferable to dissolve or disperse the insecticide in a suitable solvent, such as an oil, emulsion, or
It is preferable to use it in a liquid or paste form such as a spray agent, apply it to a substrate by a coating method, a spraying method, or an impregnation method, and then dry it as necessary to remove the solvent. When retaining the insecticide on the substrate, for example, vinyl acetate resin, acrylic resin, neoprene-based or chloroprene-based rubber,
Solutions or emulsions of nitrile rubber, natural rubber, SBR rubber, cyanoacrylate resins, cellulose, polyvinyl alcohol, etc. can be used to improve the retention of the insecticides on the substrate. The pet collar of the present invention can be obtained by cutting and processing the insecticide-retaining base material thus obtained into a suitable band shape according to a conventional method. Examples and comparative examples are given below to explain the present invention in more detail. Example 1 Each raised substrate (width 1.5 cm x length 60 cm) listed in Table 1 below was uniformly sprayed with a 2% n-hexane solution of various insecticides, or the above substrate was coated with the solution. immersed in the n-
Pet collar sample of the present invention by volatilizing hexane
Nos. 1 to 21 were obtained.

【table】

[Table] <Biological test 1> A biological test was conducted using the sample obtained above.
That is, cut the sample obtained above into a length of 10 cm, and
They were placed on the bottom of a plastic case measuring 1.5 cm, 5 cm high, and 10 cm long, and after releasing 10 dog fleas each, a net was placed on the top of the case to prevent the fleas from escaping.
The effectiveness was determined by measuring the time it took for all 10 animals to knock down, and observing the mortality rate after 24 hours in rearing conditions without any post-medication. The results are shown in Table 2 below.

【table】

[Table] Comparative Example 1 Various base materials listed in Table 3 below (width 1.5 cm x length 60
Comparative collars (Samples Nos. 1 to 10) were prepared by spraying permethrin, fenitrothion, or propoxar onto the collars (125 mg per base) in the same manner as in Example 1. Table 3 shows the results of performing biological test 1 similar to Example 1 on each of the obtained samples. Table 3 also shows commercially available DDVP
PVC resin band kneaded with 10% (sample
No. 14 (width 1.5 cm x length 60 cm x thickness 0.3 cm) and the method of making the band, apply 125 insecticides per band.
Similar test results are also shown for three types of vinyl chloride kneaded band samples Nos. 11 to 13 prepared so as to contain mg.

[Table] <Biological Test 2> Using each sample prepared in the Examples and Comparative Examples of the present invention, a test was conducted on the migration and diffusion of insecticides into the body hair of dogs. That is, each sample was separately attached to the neck of a male mongrel dog weighing approximately 15 kg, body length 45 cm, and body height 36 cm, and after 5 days, hair was removed from each dog's body in three locations 3 x 4.
The hair was cut in an area of cm ² and 200 mg of body hair was collected from each part on a waist-high shear, after which 10 dog fleas were released, and the efficacy was evaluated in the same manner as in biological test 1. The area to be cut is the area directly below the collar sample, and area 1.
The central part of the back 10 cm away from the collar sample was designated as site 2, and the central part of the back 45 cm away from the same sample was designated as site 3. The results are shown in Table 4.

[Table] <Biological Test 3> 20 dog fleas collected in advance before attaching the present invention sample and comparative material to the dog's neck.
After releasing the head onto a dog and confirming that the fleas had entered the dog's body hair, a collar was attached to each sample and the number of fleas remaining on the dog was visually counted every predetermined number of days. The dog used in the test weighed 15 kg, body length was 45 cm, and body height was 35 cm.
He is a CM male mongrel dog. . The results are shown in Table 5 below in percent remaining.

[Table] Example 2 Nylon, which is a typical brushed base material of the present invention (width 1.5 cm x length 60 cm, flocked, brushed height 5
This example was carried out ^by using permethrin, a typical pyrethroid, and adding various additives.

【table】

[Table] Example 3 and Comparative Example 2 The material of the nap is polypropylene and the height of the nap is 2
An insecticide solution was sprayed on a raised substrate having a diameter of 50 μm, a diameter of 50 μm, and a density of 100 rods/cm ² in the same manner as in Example 1, and dried in the same manner as in Example 1 to obtain pet collar sample No. of the present invention.
Got 30. Also, in the above, the height of the brushing is 0.5mm and 20mm.
Comparative pet collar samples No. 15, No. 16, and No. 17 were obtained in the same manner except that the collar was 25 mm. These samples as well as Samples No. 1 and No. 3 of Example 1
The results of biological test 1 and the results of biological test 2 for Comparative Sample No. 9 of Comparative Example 1 are shown in Table 6 and Table 7, respectively.

【table】

【table】

【table】

Claims (1)

[Claims] 1. A pet collar comprising a raised base material having a raised height of 2 to 15 mm and holding an insecticide that is non-volatile at room temperature. 2. The collar according to claim 1, wherein the insecticide that is nonvolatile at room temperature is selected from pyrethroid, organophosphorus, and carbamate insecticides. 3. The collar according to claim 2, wherein the insecticide that is nonvolatile at room temperature is a pyrethroid insecticide. 4. The collar according to claim 1, wherein the insecticide is retained on the raised substrate by a coating method, a spraying method, or an impregnation method.