JPS6230023B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention provides
The present invention relates to a device that prevents calcium from being deposited in the dialysate in a dialysis machine that uses an artificial kidney dialysate containing HCO ₃ ^- ions.

In the artificial kidney dialysate (hereinafter simply referred to as dialysate), it is desirable to include HCO ₃ ^- ions in the dialysate, and this
It is well known in the art that acetic acid and sodium bicarbonate are used as sources of HCO ₃ ^-ions . HCO ₃ ^- ion is an important ion that exists in blood and controls acid-base balance.
HCO ₃ ^- ions tend to cause carbonate to precipitate in the dialysate, and therefore it has become popular to generate HCO ₃ ^- ions through metabolism in the body using acetate ions. However, if acetate ions enter the body in excess of a permissible amount, they cause various symptoms in patients undergoing dialysis. Therefore, in recent years, sodium bicarbonate has been used again.
The idea of supplying HCO ₃ ^- ions to achieve acid-base equilibrium is being reconsidered. As mentioned above,
The drawback of dialysate fluid containing HCO ₃ ^- ions is that carbonate tends to precipitate in the dialysate fluid, resulting in negative effects on patients due to lack of calcium, etc., and scaling in patient monitoring equipment and piping. It is said that it brings about the harmful effects of

Generally, a dialysis machine separates two types of liquids with different concentrations (in this case, dialysate and blood) with a semipermeable membrane, and uses the principles of diffusion, limit excess, and osmotic pressure to
It has the function of moving waste products, toxic substances, excess water, electrolytes, etc. in the blood into the dialysate and removing it, and consists of a supply device that supplies the dialysate, a patient monitoring device, and a dialyzer. Ru. and,
Today, known dialyzers of this type include a coil type dialyzer using a tube-shaped dialysis membrane, and a hollow fiber type dialyzer using a hollow fiber as the dialysis membrane.
In addition, patient monitoring devices are usually devices that safely perform hemodialysis, such as dialysate concentration meters, dialysate flow meters, dialysate thermometers, dialysate negative pressure gauges, air bubble detectors, blood leak meters, and pressure gauges. etc., to which the dialyzer can be attached.

As a result of extensive research, the present inventors have discovered that if dialysate containing HCO ₃ ^- ions is left for a certain period of time, carbonates tend to precipitate mainly in patient monitoring equipment and piping. It was also discovered that carbonate precipitation or scaling in the dialysate could be prevented if the dialysate stagnant in the patient monitoring device and piping was drained at regular intervals and replaced with fresh dialysate. Ta.

It is therefore a general object of the present invention to provide a dialysis solution containing HCO ₃ ^- ions supplied by sodium bicarbonate to prevent carbonate precipitation or scaling that occurs during retention of this dialysis solution. Provides dialysis equipment.

In order to achieve the above object, the present invention provides a dialysate supply device equipped with a storage tank for an artificial kidney dialysate containing HCO ₃ ^- ions obtained from sodium bicarbonate, and the dialysate is drawn out from the storage tank. The piping line is branched into a plurality of pipe lines, a patient monitoring device is connected to each branch piping line via an automatic valve, and a dialyzer is connected to the patient monitoring device so that the dialysate can be bypassed at its entrance and exit, and The automatic valve is configured to selectively perform dialysis operations on a plurality of patient monitoring devices and to bypass dialysate to the dialyzer to allow dialysate to flow through the patient monitoring device at predetermined time intervals when the dialysis operation is stopped. It is characterized by being provided with a control device that performs opening/closing control.

The dialysis apparatus according to the present invention is configured such that a piping line from a single dialysate storage tank is branched and connected to a plurality of patient monitoring devices, and all or some of the plurality of patient monitoring devices are stopped. It is particularly advantageous if applied in cases where

Of course, the dialyzer is required during dialysis operation, and when the dialysis operation is stopped, the dialyzer is not connected to the patient monitoring device, and a bypass connected to its entrance and exit is connected. The tubes are connected.

Calcium precipitation in the dialysate occurs significantly when the dialysate is retained for a certain period of time, that is, at an initial pH of 7.3 for one hour or more. Therefore,
In the dialysis apparatus of the present invention, a control device, for example, a timer control device provided in the dialysate supply device
It is sufficient to open and close the automatic valve within 0.5 hour intervals to allow new dialysate to flow through. The time interval set by the timer is desirably as short as possible from the point of view of scaling, but is determined by taking into account the cost of the dialysate to be discharged. Diaphragm valves are automatic valves,
Any automatic valve suitable for dialysate can be used, such as a solenoid valve.

Hereinafter, the present invention will be further explained by way of examples with reference to the accompanying drawings.

A dialysate storage tank 1 is installed in a dialysate supply device 10 that can continuously produce dialysate containing HCO ₃ ^-ions .
2 will be provided. A plurality of patient monitoring devices 14, 16, which can link this storage tank 12 with a dialysate supply device,
18...Connect to i. This connection piping line L
are led out from the dialysate storage tank 12, and branch piping lines L ₁₄ , L ₁₆ ,
It is branched into L ₁₈ ,...Li, respectively. In addition, automatic valves are installed near the patient monitoring devices 14, 16, 18...i.
S ₁₄ , S ₁₆ , S ₁₈ , ...Si are connected, respectively. Note that the patient monitoring device is usually placed near the patient's bed. In FIG. 1, as an example, operating patient monitoring devices 16, 18, i and their branch piping lines are shown by solid lines, and stopped patient monitoring devices 14, 20, 22 and their branch piping lines are shown by broken lines.

_HCO3 obtained from sodium bicarbonate _NaHCO3 ^-
A dialysate containing ions is produced in a dialysate supply device 10, and the dialysate is supplied to a dialysate storage tank 1.
2 to each patient monitoring device 14, 16, 18,...i, but in FIG.
6, 18, i are undergoing dialysis operation, so the dialysate does not stagnate in the patient monitoring devices 16, 18, i and the branch piping lines L ₁₆ , L ₁₈ , ... Li, and therefore, the dialysis Calcium does not precipitate or scale in the liquid. however,
Since the dialysis operation of the patient monitoring devices 14, 20, 22 is stopped, the dialysate is
0, 22 and branch piping lines L ₁₄ , L ₂₀ , L ₂₂
Stagnant within. Note that dialysate will not remain in the connection piping line L unless all patient monitoring devices are stopped. If this retained dialysate continues to stay for a certain period of time or more, carbonates will precipitate in the dialysate retained in the patient monitoring device and the branch piping lines. Therefore, for example, if the patient monitoring device 14, 20, 2 is stopped,
2 and branch piping lines L ₁₄ , L ₂₀ , L ₂₂ ,
The solenoid valves S ₁₄ , S ₂₀ ,
The S ₂₂ was operated continuously open for 10 minutes to cycle through and stop the flow of dialysate, and the standing dialysate was drained to the drain line and replaced with fresh dialysate. That is,
In this embodiment, the bypass pipe automatically opens and closes when the patient monitoring device is stopped or when the patient monitoring device is in an empty state, so that the bypass pipe is automatically opened and closed so that the inside of the patient monitoring device and the branch piping line are protected. The stagnant dialysate can be periodically drained to the drain line.

When operated in this manner, no carbonate was deposited in the stopped patient monitoring device or in the branch piping line despite the long period of operation, and the operation was extremely stable and safe.

With the dialysis device of the present invention, there is no carbonate precipitation or scaling even in the stopped patient monitoring device, despite the presence of HCO ₃ ^- ions supplied from sodium bicarbonate in the dialysate.
I was able to drive for long periods of time with peace of mind. Additionally, the stopped vehicles were able to resume operation without any problems.

Although the present invention has been described above with reference to preferred embodiments, the present invention is not limited thereto, and it goes without saying that various design changes can be made without departing from the spirit of the present invention.

[Brief explanation of the drawing]

FIG. 1 is a system diagram showing an embodiment of the apparatus of the present invention. 10... Dialysate supply device, 12... Dialysate storage tank, 14, 16, 18, 20, 22, i... Patient monitoring device, L ₁₄ , L ₁₆ , L ₁₈ , L ₂₀ , L ₂₂ , Li... Branch piping line , S ₁₄ , S ₁₆ , S ₁₈ , S ₂₀ , S ₂₂ , Si...Solenoid valve.

Claims (1)

[Claims] 1. A dialysate supply device equipped with a storage tank for artificial kidney dialysate containing HCO ₃ ^- ions obtained from sodium bicarbonate is provided, and a piping line led out from the storage tank is branched into a plurality of branches to form each branch piping line. A patient monitoring device is connected to each of the patient monitoring devices via an automatic valve, a dialyzer is connected to the patient monitoring device in such a manner that dialysate can be bypassed at the inlet/outlet thereof, and the plurality of patient monitoring devices are selectively operated for dialysis. and a control device that controls the opening and closing of the automatic valve so that the dialysate bypasses the dialyzer and causes the dialysate to flow through the patient monitoring device at predetermined time intervals, stopping the dialysis operation. dialysis machine.