JPS626820B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention comprises a replaceable plate-like fluid module having a flow path with a monitoring device, and a control device for controlling fluid flowing through the fluid module to be supplied to and derived from a patient. The present invention relates to a device for processing blood in a bypass of a natural arterial system, in which an elastically deformable fluid conveying channel is actuated by a peristaltic pump arranged on the device side.

For example, such devices are used as so-called "artificial kidneys" and act as dialysis or hemofiltration devices. In all dialysis or hemofiltration devices currently on the market, blood, filtrate,
The flow path for introducing the substituent fluid or the dialysate consists of a tube set consisting of each tube and a branch pipe of each such tube. Molded members of a pressure regulating device, a blood detecting device, and an air detecting device are joined to appropriate positions of the tube assembly. Before each patient is treated, each tube must be fitted into a tube pump, heating device, and monitoring devices such as pressure regulators, blood detection devices, and air detection devices. These pretreatments were complicated and time consuming, and required great care by the operator to fit the correct tubes into the correct connections and monitoring equipment to prevent accidents from occurring.

An apparatus for performing peritoneal dialysis according to the preamble of claim 1 of U.S. Pat. As already used, in this device it is additionally necessary to connect a tube pump, which is part of the control device, to the tube-shaped conduit branching off from the module. In such "artificial kidneys" a large number of such peristaltic pumps are required for transporting blood, heparin, filtrate or dialysate, and for transporting replacement fluid, so the tubes are designed in this way. The one that fits into the pump is
Significant lag times occur between each treatment of different patients.

Because of the strict sterilization specifications for these procedures, these tube sets and modules are
These must be replaced after each treatment of a single patient, where strict sterilization requirements have made it common for these module and tube sets to be formed as single-use, disposable units. For example, such disposable units are also used to increase the oxygen content of the blood (DE-OS 2264848).

The object underlying the invention is therefore to develop a device of the above-mentioned type in a simple manner, with the flow path and the connection with the control and monitoring device of the device being significantly simplified, operationally stabilized and The goal is to make it smaller.

According to the invention, this task is achieved in that the plate-shaped fluid module covers the peristaltic pumps on the side facing the device and includes corresponding elastically deformable liquid conveying channels within the pumps. This is solved by

Other features of the invention are described in the other claims.

In the following, the invention, which allows for various embodiments, will be explained in more detail with reference to a number of exemplary embodiment drawings.

“Artificial kidney” shown as an example of use in Figure 1
operates according to the principle of a hemofiltration unit, as is known, for example, from DE 255 2 304 A1. Generally, this unit consists of a control device 1, a filtration module 2, a tube set for the flow channels and a frame 3 supporting the control device 1.

According to the invention, fluid modules 4, 5 are used instead of the tube set, which connect the flow channels 13, 1
4, 18 and 19 and surrounded therein,
It is formed by an air trap 12, a monitoring device formed by a substituent fluid heating device 17, an arterial low pressure regulator 22, a blood detection device 23, a venous pressure regulator 24 and a further pressure regulator 31.

The flow path 14 connects the substituent fluid storage container 25 to the conduit 10.
It operates in conjunction with a peristaltic pump 15 located on the side of the device for conveying the substituent fluid through the flow path, and conveys the blood from the arterial connection tube 8 to the conduit 19 and the filtrate from the filter 2 through the flow path. 18 and a peristaltic pump 21 for discharging through conduit 9 into a collection vessel 27 for the filtrate.

In the filtration module 2, substances excreted from the kidneys together with serum are removed from the blood, the concentrated blood being returned through the flow channel 13 into the venous connection 7 and thus to the patient. After the serum and other biologically necessary substances removed from the blood are at least partially replaced and together with heparin flow from the storage container 25 through the replacement fluid heating device 17, via the fluid line 14 into the air trap. 12, where it is mixed with blood to be concentrated and delivered to the patient.

Removal of substances excreted by the kidneys is carried out in the storage container 2.
5, the storage container 25 is hung on a scale connected to the control device 1 via the hook 26, and the collection container 27 is attached to the handle in the same manner. 29 and hang it on the hook 28 of the second weighing device or the common weighing device.

The fluid modules 3, 5 are precisely positioned in the control device 1 by means of a fixing device 6, in which case the members 16 and 20 of the peristaltic pumps 15 and 21, which are in contact with the fluid modules 4, 5, are positioned precisely in the flow path 1.
4, 18, and 19 intermittently. In the same way, sensors arranged on the instrument side, microswitches as well as an ultrasonic oscillator 32 (FIG. 7) acting on the air trap 12 are operatively connected to the fluid modules 4, 5.

Obviously, the filtration module 2 shown in FIGS. 1 and 2 can be replaced by a dialysis module. This requires a connection line for the dialysate supply, which corresponds to the channel 18. Advantageously, the fluid modules 4 , 5 can be supplemented with an additional dialysate pump, an additional flow path for the dialysate and a storage container for the dialysate arranged in the frame 3 . In this case, a collection container 27 serves to receive the used dialysate via the conduits 9, 18.

As is clear from FIG.
8, 19 pass into the pluggable connecting tubes 2a, 2b, 2c of the filtration module 2, so that this filtration module together with the fluid modules 4, 5 can form an enclosed unit. In another direction, the connecting pipe 13 for connecting the channels 13, 14, 18, 19 with the tubes 7, 10, 9, 8
a, 14a, 18a, 19a. Peristaltic pumps 15 and 21 have one or more pumps acting on the flow channels 14, 18, 19 on their support discs arranged at a slight angle to the plane of the fluid modules 4, 5. Protrusions 16a and 20
These protrusions are arranged around the circumference of the support disk and act on the soft back surface of the plate 5 when rotated.

As can be clearly seen from FIG. 5, the peristaltic pump 15
A ball 16a mounted rotatably in the interior or its rotor intersects the surface of the module member 5 and deforms this member as shown in FIG. direction into the air trap. Peristaltic pump 21 works together with bulb 20 and channels 18, 19 according to the same principle. Due to the rotatably mounted ball 16a,
Friction resistance can be reduced. This also means that in the rotor of the peristaltic pump 15, 21,
This can be achieved by disposing pivotably mounted rollers instead of the balls 16a, which rollers project axially to the same extent as the pivotably mounted balls 16a. Instead of balls or rollers, fixed protrusions may also be used, which compress the elastically deformable members 14, 18, 19 of the fluid modules 4, 5 when the rotor rotates. In particular, in this case the friction between the protrusion surface and the plastic module is somewhat greater than if it were implemented using balls or rollers.

In the embodiment according to FIGS. 2 and 3, the fluid module 4, 5 consists of two half-shells 4 and 5a of essentially the same construction, in which case the side 4 facing away from the control device 1 is itself rigid. It is also used as a support plate 4 for another elastically deformable half shell 5a facing the control device 1. According to Figure 4, by transforming this,
The module half 5b facing the control device 1 can be designed as an unshaped planar plate.

In another embodiment according to FIG. 7, the fluid module consists of two flexible plates 4c, 5c, in which case the plate 5c facing the control device 1 rests flatly on the casing 1a and these two plates 4c and 5c is a hard pressure plate 33
is fixed to the casing 1a by. This localization is performed by the centering pin 6, and the fixing is performed by, for example, a toggle 6a disposed on the localization pin 6.
Or by other gripping members. In the area of the monitoring device and in the area of the flow channels 14, 18, 19 connecting with the peristaltic pumps 15, 21, cutouts 1b are provided in the casing 1a, so that, for example, the ultrasonic oscillator 32 and the air trap 12 can be in contact with the protrusions 16 with the balls 16a arranged on the support disk 15 and the flow channels 14, and these are deformed according to FIGS. 5 and 6.

Depending on the material used, for example the type of plastic, these two plates 4, 5 can be glued, welded or otherwise bonded tightly together to form tight channels 13, 14, 18 and 19. Airtightly connected.

In an embodiment not shown, two plates 4, 5 are provided which are not tightly connected to each other, into the molded space of which a self-tight tube assembly is fitted, which is pre-mounted. It also satisfies the above-mentioned conditions as a constituent member.

Also, instead of the peristaltic pumps 15 and 21 shown, other motor-driven pumps with eccentric plates and projections acting on the flow path can be provided. Obviously, it is also possible to arrange the support disk 15 inside the module, so that this disk can be connected with the motor 15a of the pump with a centering fitting joint. According to this, among other things,
The costs of disposable components are increased, which makes the fluid module expensive without any particular advantages being gained thereby.

The advantage of the fluid module 4, 5 is that the blood volume that is transported within this system and maintained in very short connecting tubes is very small, and that a specific filtration module or dialysis device is included in this module. It is possible to do so. Preparing the device for a new procedure is simple and can also be carried out by less trained personnel.
The irreplaceably fixed connecting tube further reduces the risk of the operation. Furthermore, the simple construction of the fluid modules 4, 5 is suitable for industrial manufacture, which is an advantage in such a disposable unit and does not have to be configured for long-term use.

[Brief explanation of the drawing]

1 is a perspective view showing one embodiment of the device according to the invention, FIG. 2 is an enlarged plan view showing one embodiment of the fluid module with its surface shell removed, and FIG. 3 is the same as in FIG. Part B of the fluid module
4 is a sectional view taken along line A--A of the fluid module shown in FIG. 1; FIG. 5 is an enlarged view taken along line C--C of FIG. 4 showing the action of the cam on the pipe line. The sectional view, FIG. 6, is D in FIG.
- A sectional view taken along line D and FIG. 7 are enlarged sectional views showing other embodiments of the fluid module. DESCRIPTION OF SYMBOLS 1... Control device, 2... Filtration module, 3... Frame, 4, 5... Fluid module, 7, 8, 9, 1
0... Conduit, 12... Air trap, 13, 14... Channel, 15... Peristaltic pump, 16... Pump member, 17
... Substitute fluid heating device, 18, 19... Channel, 20... Pump member, 21... Peristaltic pump, 22... Arterial low pressure regulator, 23... Blood detection device, 24... Venous pressure regulator,
25... Substitution liquid storage container, 26... Hook, 27... Filtrate collection container, 28... Hook, 29... Handle, 32...
Ultrasonic oscillator, 33...pressure plate.

Claims (1)

Claims: 1. A replaceable plate-like fluid module having a flow path with a monitoring device and a control device for controlling fluid flowing through the fluid module to be supplied to and derived from a patient; In a device in which an elastically deformable fluid conveying channel is actuated by a peristaltic pump arranged on the device side, a plate-shaped fluid module covers the peristaltic pumps 15, 21 with the side facing the device 1 and the pump A device for processing blood in a bypass of the natural arterial system, characterized in that it includes within its scope elastically deformable liquid conveying channels 14, 18, 19 corresponding to these pumps. 2. The plate-shaped fluid module consists of two shell-shaped molded bodies 4 and 5 connected to each other,
Device for processing blood in a bypass of the natural arterial system according to claim 1, characterized in that flow channels (13, 14, 18, 19) are enclosed therein. 3 The shaped body is formed from two rigid plates 4, 5 connected to one another, of which the plate 5 facing the control device 1 is in elastically deformable contact with the peristaltic pumps 15, 21. The first and second claims are characterized in that:
A device for processing blood according to any of the preceding paragraphs in a bypass of the natural arterial system. 4 The molded bodies 4 and 5 are themselves hard support plates 4
and an elastic plate 5a or 5b facing the peristaltic pumps 15, 21 and deformable by the mechanical control members 16, 20, 32 of the control device 1. and a device for processing blood in a bypass of the natural arterial system according to any of the preceding clauses. 5. A fluid module formed from elastically deformable plate-shaped molded bodies 4c, 5c is fixed to the control device 1 between the pressure plate 33 and the casing of the control device 1. A device for processing blood according to any of clauses 1 and 2 in a bypass of the natural arterial system. 6 Half shells 4 whose molded bodies are generally the same,
Device for processing blood in a bypass of the natural arterial system according to any one of claims 1 to 5, characterized in that it is formed from 5a. 7 a plate 5 whose shaped body is generally flat;
5b, 5c, and shells 4, 4c that accommodate flow paths 13, 18, 19 and monitoring devices 12, 17, 22, 23, 24. 6. A device for processing blood in a bypass of the natural arterial system according to any of clauses 5. 8 flow paths 13, 18, 19 and monitoring device 12,
17, 22, 23, 24 are formed by a set of tubes fixed between the plates 4, 5, wherein blood is processed in a bypass of the natural arterial system according to claim 1. device to do. 9 Elastically deformable member 1 of fluid modules 4 and 5
4, 18, 19 are driven by motor-driven rotors 15, 2 rotating in the feed direction.
1, in which case each rotor 15, 21 has at least one roller or ball projecting axially and pivotably mounted in this rotor, or a fixed projection 16 projecting from the rotor 15, 21. , 20, when the rotors 15, 21 rotate, the fluid modules 4, 20
9. A device for treating blood in a bypass of a natural arterial system according to any one of claims 1 to 8, characterized in that the device compresses the elastically deformable members 14, 18, and 19 of No. 5. 10 The surfaces of rotation drawn by the rotors 15 and 21 or their rotational axes are slightly inclined with respect to the surfaces of the fluid modules 4 and 5, and the protrusions 16
A, 20 rotation surface is elastically deformable flow path 14,1
8 and 19, and compresses the flow channels 14, 18, 19. A device for processing during bypass of the arterial system. 11 Fluid modules 4 and 5 connect to connecting pipes 2a and 2
b, 2c, directly connected to the filter 2 or the dialysis machine to form the units 2, 4, 5. Equipment that processes during system bypass. 12 Flow paths 13, 14 of fluid modules 4, 5,
18, 19 are tube connection pipes 13a, 14a, 1
Device for processing blood in a bypass of the natural arterial system according to any one of claims 1 to 11, characterized in that it terminates in 8a, 19a. 13 The monitoring device includes an air trap 12, a heating device 17, a blood detection device 23, a pressure regulating device 22, 24,
31, which are arranged on the device side and form an ultrasonic oscillator 32 for the air trap 12.
Device for treating blood in a bypass of the natural arterial system according to any one of claims 1 to 12, characterized in that it corresponds to control elements, sensors and microswitches such as. 14. The fluid module according to any one of claims 1 to 13, characterized in that the filter module 2 or the dialysis device or the membrane filtration module is assembled as a molded member in the fluid modules 4 and 5. A device that processes blood in a bypass of the natural arterial system. 15. characterized in that a large number of channels 18, 19 are arranged in one common peristaltic pump 21,
Apparatus for treating blood in a bypass of the natural arterial system according to any one of claims 1 to 14.