JPS6320550B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION <Industrial Field of Application> The present invention relates to an infusion bag. More specifically, glucose solution and amino acid solution can be stored separately.
The present invention relates to an infusion bag that allows the two infusion solutions to be mixed simply and aseptically prior to infusion.

<Conventional technology> In recent years, technological advances in high-calorie infusions and artificial intestinal tubes have been remarkable, and they are now being widely adopted for life support for many patients.However, in order to avoid deterioration of the infusions administered to patients, , multiple infusion solutions such as glucose solution and amino acid solution are stored separately in bottles,
Before use, the medicinal solution in each bottle is transferred and mixed into one bottle or bag using an infusion set or the like, or the two bottles are communicated with each other through a connecting tube with liquid guide needles at both ends. I was given an infusion.

<Problems to be Solved by the Invention> However, the above-mentioned method of transferring and mixing infusions into one bottle or bag requires a plurality of bottles containing infusions to be mixed, bottles or bags for mixing, infusion sets, etc. This problem not only requires a large number of containers and equipment, but also requires extremely careful handling in order to carry out the transfer and mixing operations aseptically.

In addition, the above-mentioned method of infusing the two bottles in fluid communication does not allow the two solutions to mix completely, especially when infusing glucose and amino acid solutions together, which are poorly absorbed in the body unless they are thoroughly mixed. However, there was a drawback that the glucose solution, which is a hypertonic solution, was injected first, and the amino acid solution was injected later, resulting in poor absorption of the medicinal solution into the body, which was a problem.

The present invention has been made in view of the above problems, and
The purpose is to provide an economical infusion bag that can separately contain a glucose solution and an amino acid solution and that can easily mix the two solutions in an aseptic manner.

<Means for Solving the Problems> That is, the present invention provides a flexible bag in which a first chamber containing an amino acid solution and a second chamber containing a glucose solution are defined in a fluid-tight manner. The volume of the second chamber is large enough to accommodate the entire amount of the amino acid solution in the first chamber in addition to the amount of glucose solution accommodated, and the volume of the second chamber is large enough to accommodate the entire amount of the amino acid solution in the first chamber. This is an infusion bag in which an openable communication means that enables communication between the two chambers is provided on the partition band of the chamber.

<Function> Since the infusion bag of the present invention has two chambers that are partitioned in a liquid-tight manner, a single bag can separately contain and store a glucose solution and an amino acid solution.

In addition, the volume of the second chamber is large enough to accommodate not only the amount of glucose solution contained therein but also the entire amount of amino acid solution in the first chamber, so by opening the communication means of the partition band, it is possible to prevent leakage from the outside. The entire amount of the amino acid solution can be transferred to the glucose solution by pressure, etc. Therefore, by placing the second chamber facing down and applying pressure from the outside or shaking, the drug solution can be mixed easily and aseptically. It can be performed.

<Example> Next, an example of the present invention will be described based on the drawings.

FIG. 1 is a front view of an infusion bag according to an embodiment of the present invention (the inlet for the drug solution is omitted), and FIGS. 2 to 6 are enlarged views of examples of communication means that can be opened. .

As shown in FIG. 1, an infusion bag 1 of the present invention is an infusion bag made of a flexible sheet, for example, a soft vinyl chloride sheet, and is divided into two chambers 4 and 5 by means such as fusing. The partition band 2 is provided with an openable communication means 3 that allows the two chambers 4 and 5 to communicate with each other. The volume of the second chamber 4 that accommodates the glucose solution is sufficiently larger than the amount of glucose solution that is accommodated, and the volume of the second chamber 4 that accommodates the glucose solution is sufficiently larger than that of the first chamber 5.
It is large enough to transfer the entire amount of amino acid solution stored in the container.

The communication means 3, as clearly shown in FIG.
Part of the partition strip 2 of the two adjacent chambers 4 and 5 is opened to form a flexible tube portion 6, and a rigid ball 7 made of stainless steel or the like is installed in the tube portion 6.
However, they are tightly fitted to close the tube portion 6 so that the liquids in both chambers 4 and 5 do not mix.

When in use, first hang the infusion bag 1 on a hanger or the like with the second chamber 4 facing down.
Next, the rigid ball 7 is detached from the tube part 6 with a finger to make the two chambers 4 and 5 communicate with each other, and the upper first
from chamber 5 to the second chamber below. Then, the amino acid solution and the glucose solution are mixed by manual pressure or shaking from the outside, and the infusion solution is supplied to the patient from the outlet port 8.

If it is necessary to add a small amount of ingredients such as vitamins or electrolyte solution, a self-closing plug 9 made of an elastic material such as rubber as shown in FIG. This plug 9 with a syringe needle
The liquid in the syringe can be supplied into the infusion bag by puncturing the syringe.

FIG. 3 shows a communication means provided with a means for preventing the rigid ball 7 from unintentionally detaching from the tube portion 6 during transport of the infusion bag 1, and includes a flexible tube 10 extending slightly into both the upper and lower chambers. Partition band part 2
This tube 1 is connected by a rigid ball 7.
After closing the tube 10, the vertically extending portion of the tube 10 is closed with a hairpin-shaped clamp 11, thereby blocking communication between the upper and lower chambers. In use, the clamp 11 may be opened by operating from the outside of the infusion bag, the rigid ball 7 may be removed, and the upper and lower chambers may be communicated with each other.

The communication means shown in FIG. 4 has a rigid tube 12 made of synthetic resin sealed at one end placed in an opening provided in a part of the partition band 2 to block communication between the upper and lower chambers until use. be. When in use, the sealed end of the rigid tube 12 is held from the outside of the infusion bag and a threaded opening is made to communicate the upper and lower spaces.In order to facilitate thread cutting, a portion of the rigid tube 12 is weakened. It is preferable to provide a narrow part 13 as a part or to provide a cut on the outer periphery of this narrow part 13.

The communication means shown in FIG. 5 seals a tube-shaped opening provided in a part of the partition band 2 with a synthetic resin diaphragm 15, and when in use, a hollow needle 17 sealed in either the upper or lower chamber. Tsute diaphragm 15
It is used to pierce through and connect the upper and lower spaces.

As shown in the figure, if the hollow needle 17 is housed in the holding chamber 16 and a holding part that supports the proximal end of the hollow needle 17 is provided in the holding chamber 16 to fix the hollow needle 17, it is possible to Since the hollow needle 17 can be prevented from moving, the hollow needle 17 is prevented from piercing the diaphragm 15 or the sheet constituting the infusion bag until use.

The communication means shown in FIG. 6 consists of a diaphragm 19 disposed in a tube 18 extending from the opening of the partition band 2 to the outside of the bag, and a hollow needle 20 that can pierce the diaphragm 19. It is slidably and tightly fitted and supported within the tube 18. Communication operation is performed using the empty needle 20 located outside the bag.
By holding the proximal end of the tube 18 and advancing the empty needle 20 to break the diaphragm 19, the empty needle 20 is moved back to open the side hole 21 provided outside the diaphragm 19 of the tube 18. conduct. Since this communication means can directly hold the proximal end of the empty needle 20 without using an infusion bag, the communication operation becomes reliable.

Also, the empty needle 20 may accidentally fall off or the empty needle 2 may fall off accidentally.
In order to prevent liquid leakage between the empty needle 20 and the tube 18, the proximal end of the empty needle 20 can be sealed with a flexible bag 22.

<Effects> As is clear from the above explanation, the infusion bag of the present invention has the following advantages.

(1) A single bag can store and store separately an amino acid solution and a glucose solution in amounts that provide the desired mixing ratio.

(2) Since the second chamber is large enough to sufficiently accommodate the amino acid solution and glucose solution to be mixed, mixing of both solutions is easy.

(3) Amino acid solution and glucose solution can be mixed aseptically.

[Brief explanation of the drawing]

Figure 1 is a front view of an infusion bag according to an embodiment of the present invention (the drug solution inlet is omitted);
6 through 6 are enlarged views of examples of unsealable communication means, respectively. <Explanation of main symbols>, 1: Infusion bag, 2: Partition band, 3: Communication means, 4: Second chamber, 5: First
room.

Claims (1)

[Scope of Claims] 1. A flexible bag comprising a first chamber containing an amino acid solution and a second chamber containing a glucose solution, which are liquid-tightly defined, The volume of the chamber is large enough to accommodate not only the amount of glucose solution accommodated but also the entire amount of amino acid solution in the first chamber,
and on the partition band between the first chamber and the second chamber, said 2
An infusion bag provided with an openable communication means that enables communication between two chambers. 2. The infusion bag according to claim 1, wherein the communication means comprises a flexible tube and a rigid ball that closes the tube. 3. The infusion bag according to claim 1, wherein the communication means is a rigid tube sealed at one end and provided with a breakable weakened portion for opening the sealed portion. 4. The infusion bag according to claim 1, wherein the communication means comprises a tube-shaped opening, a diaphragm that seals the tube-shaped opening, and a hollow needle that can pierce the diaphragm. 5. The infusion bag according to claim 4, wherein the hollow needle is housed in a holding chamber provided with a holding part that supports the proximal end of the hollow needle within the flexible bag. 6. The communication means comprises a tube extending from the first chamber to the outside of the bag, a diaphragm disposed within the tube, and a hollow needle capable of piercing the diaphragm, and the body of the hollow needle slides inside the tube. A patent claim characterized in that the tube is movably supported in a tight fit, the tube is provided with a side hole communicating with the second chamber, and the proximal end of the empty needle is disposed outside the bag. The infusion bag according to item 1 of the scope of the invention. 7. The infusion bag according to claim 6, wherein the proximal end of the empty needle is sealed with a flexible bag.