JPH0130500B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a method for dispensing a medicinal solution using the pressure of compressed gas, and a medicinal solution storage and immediate-acting dispenser.

Traditionally, when injecting a drug solution into a patient, if the container containing the drug solution is glass, the process of transferring the drug solution to a syringe involves cutting open the head of the ampoule with a cutter and connecting it to the barrel of the syringe. The tip of the syringe needle is inserted into the drug solution in the ampoule through the cut-out opening of the ampoule, and the tip reaches the bottom of the ampoule. The piston, which is fitted in the cylinder body so that it can move forward and backward, is moved back and the drug solution is poured into the tube. At least three stages of inhalation work are required, which is complicated and time consuming.

In addition, when the operator cuts the ampoule, there is a risk of injuring the tip of the finger with the cut end or fragments, and if the operator is not skilled, there is a mental anxiety that the operator may not be able to properly incise the ampoule in the event of an emergency. Also, when the ampoule is cut open, microscopic fragments may get mixed into the drug solution, or when the ampoule is cut with a cutter, fine glass shavings may adhere to the cut end, and this powder may fall into the drug solution inside the ampoule. There was a risk of inhalation into the syringe, and if injected into the patient, there was a risk that it could enter the blood vessels or the body and cause adverse effects, or it could sting the skin of the fingertips of the person being treated. Furthermore, when a fingertip is injured, there is a risk of natural bacterial infection from the wound, or of bacterial infection from the patient to the treating person or from the treating person to the patient.

In addition, in the case of a drug vial whose opening is sealed with an airtight rubber cap, the problems encountered with ampoules are eliminated, but the two-step process of passing the needle through the cap and inhaling into the barrel is necessary. In addition, depending on the type of medicinal solution, the airtight rubber lid is thick, so there is a problem in that skill is required to penetrate the injection needle without bending or breaking it.

Furthermore, in the case of both ampoules and bottles, when the remaining amount of the drug solution becomes low, these containers must be tilted and inhaled into the syringe. Air often gets mixed into the syringe near the end of the process, and in this case it is necessary to turn the syringe upside down and push the piston upwards to expel the air.This step also involves drawing the drug into the syringe and injecting it. Since four to three stages of work are required to reach a possible state, it is time-consuming and labor-intensive when urgent treatment is required or when injecting a large number of patients, resulting in a lack of promptness.

Furthermore, when injecting a large amount of drug into a patient, the operator must hold the cylinder in one hand and press the piston with the fingers of the other hand, which occupies both hands and injects slowly. There is a problem in that the fingertips feel tired because they have to take a long time to administer the injections, and the degree of fatigue increases especially when injecting a large number of patients.

In addition to directly injecting the medicinal solution in the ampoule into the patient, when injecting a mixture of nutrients, hemostatic agents, antihypertensive agents, etc. into an intravenous drip container, it is also possible to inject one bottle of each of the above drugs from each ampoule or storage container. It is necessary to inhale and mix an appropriate amount of each drug into a syringe, and then inject it from the syringe through a needle into an IV container after inhalation. During injection, a thick needle is used, and in order to avoid leaving unnecessary needle hole marks on the lid of the drip container (to prevent oxidation due to air intrusion from the needle hole marks), it is necessary to replace the needle with a thinner needle. Similarly, it has the drawbacks of being cumbersome and lacking in speed, and since the syringe used to inhale various drugs has been mixed with other drugs, it has to be used again by inhaling different drugs into a separate drip container. Since it is not possible to do so, the uneconomical cost of discarding the syringe after each use cannot be avoided.

In addition, since antibiotics tend to deteriorate when stored in liquid form, they are usually powdered and stored in a sealed container, and when used, the container of the solvent solution stored in a separate ampoule or container is cut open. Alternatively, the number of steps required to insert or pierce the syringe needle into the lid of a storage bottle and aspirate the solvent solution into the syringe, the number of steps required to pierce the lid of the antibiotic sealed container with the syringe needle that inhaled the solvent solution, and the number of steps required to inhale the solvent solution into the syringe, This method requires four steps: injecting and mixing the powder into a sealed antibiotic container, melting the powder into a liquid form, and inhaling the liquid antibiotic into a syringe again, which is very time-consuming and time-consuming. There was a problem in that it was difficult to respond to emergencies.

In order to eliminate the various drawbacks of the conventional art, the present invention divides the inside of a single container with a sliding valve, stores the chemical solution in one chamber, and compresses and seals the gas in the other chamber. Formed so that the medicinal solution can be poured out by the expansion pressure,
Simplification of procedures, safety, cleanliness, ease of handling, and promptness in emergencies when injecting into patients, injecting various drugs into IV containers, and injecting solvent solutions into antibiotic storage containers, This invention aims to improve responsiveness to a large number of patients and eliminate fatigue in the fingers of the operator.

An example of the implementation of the present invention will be described with reference to the drawings. 1 is a cylindrical container made of glass or synthetic resin that has pressure resistance and corrosion resistance; 2 is a vertical cross-section made of a material that has pressure resistance and corrosion resistance against chemical solutions; It is a sliding valve formed in a U-shape, and can be slid freely into the container 1 with the opening space 2c facing the front chamber 3 side and the front and rear bulging edges 2a, 2b in airtight contact with the inner surface 1a of the container 1. It is fitted. Bulging edges 2a, 2b are integrally provided on the front and rear peripheral edges of the outer peripheral wall of the sliding valve 2, and a small recess 2d is formed around the center. The outer diameter R of the sliding valve 2 at the formed portion is formed so that it is slightly larger than the inner diameter r of the container 1, so that the bulging edges 2a and 2b are formed on the inner surface 1a of the container 1.
(Fig. 2). A medical solution 4 is stored in the front chamber 3 of the container 1 divided by the sliding valve 2, and a front stopper 7 is airtightly fitted into the tip opening 1b. The front stopper 7 is made of a material that has not only pressure resistance, but also corrosion resistance and airtightness against the medicinal solution stored in the front chamber 3, and is also flexible enough to be penetrated by the injection needle 5. Further, the rear end opening 1c of the container 1 is hermetically fitted and sealed with a pressure-resistant and corrosion-resistant rear plug 8, and then gas is pressurized into the rear plug 8 through, for example, a syringe needle. A substance that does not cause a chemical change to or undergo a chemical change from the chemical liquid 4 stored in the chemical liquid 4 is press-fitted.

In the above embodiment, the rear plug 8 is fitted into the rear end opening 1c of the rear chamber 6 of the container 1, and then gas is filled in. However, when manufacturing the container 1, as shown in FIG. is sealed in advance, the sliding valve 2 is fitted from the tip of the container 1, the tip is curved, the front stopper 7 is fitted, and the space between the front stopper 7 and the sliding valve 2 is closed. Taking advantage of the fact that the volume of the rear chamber 6 is reduced by creating a vacuum and then sliding the slide valve 2 rearward while pressurizing the chemical solution 4 into the front chamber 3 through the front plug 7, Pressure can also be maintained by compressing the air inside 6.

In addition to the one shown in the figure, the injection needle 5 used when using the injector of the present invention is also pressure resistant and can open and close the passage of the needle each time it is used in order to make it possible to divide the number of injections of the drug solution. A device equipped with an on-off valve mechanism may also be used.

In the figure, 2c is an opening space opened to the sliding valve 2,
During injection, compressed gas G in the rear chamber 6 is released while the sliding valve 2 is sliding.
If even a small amount of gas enters the front chamber 3, at the end of the injection when the drug solution is gone, the gas will enter the opening space 2c.
This is the space where the injection remains and is not injected into the patient.

Since the present invention is configured as described above, when injecting, hold the container 1 in one hand and use the other hand to insert the rear end 5b of the injection needle 5 halfway into the front stopper 7, and then insert the tip 5a, for example. When the injection needle 5 is inserted into the patient's blood vessel, and then the middle part of the injection needle 5 is held between two fingers of the other hand and the rear end 5b is penetrated into the anterior chamber 3, the drug solution 4 in the anterior chamber 3 is injected. Since it is possible to inject into the blood vessel through the inside of the needle 5, the expansion force of the compressed gas in the rear chamber 6 pushes the sliding valve 2 toward the front chamber 3 side while maintaining airtightness with the inner surface 1a of the container 1. The medical solution 4 is injected into the blood vessel through the injection needle 5 until the compressed gas reaches its density at room temperature and the sliding valve 2 stops sliding.

According to the present invention, when the rear end of the syringe needle is passed through the front stopper, the liquid in the container is automatically transferred to the outside because the sliding valve slides toward the front chamber due to the expansion force of the compressed gas. It can be used as a syringe immediately by simply inserting a needle into the front chamber of the container.
The container itself serves to store the drug solution, and there is no need to cut open the ampoule, insert the needle into the ampoule, or draw the drug solution from the ampoule into the syringe, reducing the number of steps and time. In addition, concerns such as the possibility of injury to the fingertips when cutting the ampoule, and concerns about whether or not to open the ampoule properly are eliminated, allowing injections to be performed with mental stability, and there are no cuts to the fingertips of the person performing the treatment. Because of this, there is no risk of natural bacterial infection among the treating person, or from the treating person to the patient, or from the patient to the treating person.
Furthermore, there is no risk of fragments or fine powder powder from cutting the ampoule getting mixed into the drug solution or getting mixed into the patient's body along with the drug solution. Additionally, the need for skill in inserting a needle into the lid of a drug solution bottle is eliminated.

In addition, since the medicinal solution is used while stored in the front chamber of the container, even if the drug, such as a hematopoietic agent, oxidizes and loses half its potency when exposed to air, this reduction in potency will not occur. There is no danger, and the medicinal effects can be exerted as they were at the time of manufacture. Furthermore, by using thick and thin injection needles, it is possible to adjust the injection speed and amount of the drug solution depending on the patient's condition and whether the patient is elderly or young.

In addition, if the degree of compression of the gas is calculated in advance and the volumes of the front and rear chambers are determined to store the chemical solution and compressed gas is sealed so that all the chemical solution can be poured out, no chemical solution will remain after use. There is no need to inhale air into the syringe by tilting the ampoule or liquid medicine bottle, as is the case with conventional methods, or to expel air mixed into the syringe just before the end of inhalation, making it possible to use the liquid medicine economically and effectively. It is easy to operate, and there is no need to press the piston with your fingertips, so there is no finger fatigue that occurs when injecting a large amount of medicinal solution. Furthermore, since the drug solution is dispensed by penetrating the syringe needle into the container, combined with the one-handed operation, it is possible to immediately respond to emergencies. If you use a needle with an on-off valve mechanism that can be operated from the outside and that can withstand the pressure of dispensing the drug solution in the passage through which the drug solution passes inside the needle, you can open and close the needle without injecting all the drug solution at once. Since the required amount can be automatically injected each time by opening and closing the valve mechanism, it is possible to efficiently save labor even when injecting many patients, and treatment can be performed without causing finger fatigue. It is something.

In addition, when injecting various medicinal solutions into an IV container, if you have multiple dispensers containing each medicinal solution, there is no need to change needles between inhalation and injection as in conventional methods. , since various medicines can be injected into the drip container at the same time by piercing the lid of the drip container with a needle that has passed through the drip container and each syringe, the time required for mixing and injecting is reduced compared to conventional methods. The number of steps required is significantly reduced, immediate efficacy can be achieved in emergencies and for a large number of patients, and each dispenser can be used until the drug runs out, so there is no waste. In addition, as shown in Fig. 5, the openings at both ends of the antibiotic container A that stores the antibiotic drug K are pressure-resistant, corrosion-resistant, and airtight, with a front stopper that is flexible enough to be penetrated by a syringe needle. If the rear stopper C is fitted in an airtight manner, the tip 5a of the injection needle 5 that is passed through the front stopper 7 of the syringe of the present invention is passed through the rear stopper C of the antibiotic container, and the antibiotic container The solvent solution 4 in the spout is passed through the syringe needle 5 by the pressure of compressed gas into the antibiotic container. Since the solvent solution 4 is poured out forcefully under pressure, the powder of the antibiotic agent K is melted and mixed at the same time as the injection, and the container is vibrated again to dissolve the antibiotic agent and the solvent. There is no need to mix the antibiotic solution with the antibiotic solution, and at the same time, the drug solution containing the antibiotic dissolved in the solvent solution is poured out from the injection needle N inserted through the front stopper R of the antibiotic container A. That is, the antibiotic-containing drug solution is dispensed into the patient's body by two operations: communicating the injector of the present invention and the antibiotic container with a syringe needle, and passing another syringe needle through the tip of the antibiotic container. Since it can be injected into a patient or injected into a drip container, it can significantly reduce the number of steps required compared to conventional methods, and as mentioned above, it can also be immediately effective in emergencies and when treating a large number of patients. Further, the dispenser of the present invention can be used as a dispenser for extinguishing fires, insecticidal solutions, cosmetic liquids, and other various drugs and medicinal solutions, and has an extremely wide range of applications.

[Brief explanation of drawings]

The drawings show an embodiment of the present invention, and FIG. 1 is a longitudinal sectional side view of the injector of the present invention, in which a hypodermic needle fitted into the injector is shown in imaginary lines. Figure 2 is a vertical side view of the sliding valve, Figure 3 is a vertical side view of the dispenser with the syringe needle passed through it, and Figure 4 is the rear end of the container sealed integrally with the container. A vertical sectional side view of an embodiment of
FIG. 5 is a sectional view showing a state in which the dispenser of the present invention is used in conjunction with an antibiotic storage container. Code: 1...Container, 1a...Inner surface, 1b...Tip opening, 1c...Rear end opening, 2...Sliding valve, 2
a, 2b... bulging edge, 2c... opening space, 2d
... recess, 3 ... front chamber, 4 ... drug solution, 5 ... injection needle, 5a ... tip, 5b ... rear end, 6 ... rear chamber,
7... Front plug, 8... Rear plug, R... Outer diameter (of the sliding valve), r... Inner diameter (of the container), G... Compressed gas, K
...Antibiotic drug, a...Antibiotic container, b...
Front stopper, Ha... Rear stopper, D... Syringe needle.

Claims (1)

[Claims] 1 A sliding valve 2 that slides with its peripheral edge in airtight contact with the inner surface 1a of the container 1 is fitted into the container 1, and the sliding valve 2
A medicinal solution 4 is stored in the front chamber 3 of the container 1, which is divided by
A front plug 7 made of a material that can be penetrated is hermetically fitted, and compressed gas G is filled in the rear chamber 6 to open the rear end opening 1c.
The rear stopper 8 is airtightly fitted to the injection needle 5, and the rear end 5b is sharpened so as to be able to penetrate the front stopper 7.
A medicinal liquid storage and immediate-acting dispenser consisting of.