JPH0146032B2 - - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION In the medical field, in order to test specimens such as blood and serum collected from patients, the present invention allows the specimens to be aspirated into a plurality of syringes (syringe barrels) that can be supported in parallel. This invention relates to an improvement in a syringe in a test dispensing device that dispenses a predetermined amount into test holes installed in parallel in a plurality of test tubes or titration plates that can be supported in parallel.

In the medical field, the above-mentioned test dispensing device, which dispenses specimens collected from patients into a large number of test tubes or titration plates arranged in parallel in order to be subjected to a large number of tests, is a conventional test dispensing device. In the case, as shown in Fig. 2, the mount 1 installed on the aircraft body a
A head 3, in which a large number of syringes 2 (syringe barrels) are supported in parallel, is supported so that it can freely move up and down with respect to the pedestal 1, and each syringe 2, in which the heads 3 are supported in parallel, is Each cylinder 20 is fixedly supported on a support base 30 fixed to the head 3, and the upper end of each piston 21 that is slidably fitted to each cylinder 20 is movable up and down with respect to the support base 30. Each of the pistons 21 is fixedly attached to the lifting plate 31 of the piston 21, and the lifting plate 31 is moved up and down with respect to the support base 30 by the operating member 4 provided on the head 3, so that each piston 21 is moved up and down at the same time. Each cylinder 20 is made to aspirate and discharge a specimen, and a test tube into which a specimen is injected is mounted on the sample testing station U of the machine a as shown in FIG. One of the test tube racks 5 supporting the test tubes 50 is moved by the guide rail 6 and positioned below the head 3. In this state, the head 3 is lowered, and then the elevator plate 31 is raised to place each syringe 2 on the rack. After the suction operation is performed, the head 3 is raised, and from that state the test tube rack 5 is sent to the sampled rack station V provided on the machine body a. One of the test tube racks 7 supporting the empty test tubes 70 stored in W is sent through the guide rail 6, and from this state the head 3 is lowered, and then the elevator plate 31 is lowered. Dispense the sample into each test tube 70..., send the dispensed test tube rack 7 to the dispensing rack station Y installed in the machine a, pull out a new empty test tube rack 7, and dispense. I try to continue.

After completing this dispensing operation, a new rack 5 is pulled out from the sample testing station U to aspirate the sample, and the same dispensing is continued. In order to prevent the newly sampled sample from being contaminated by the previous sample, a third
As shown in the figure, a disposable tip 8 (a cap-shaped pipette made of synthetic resin material) is attached in a removable manner, and the sample is drawn up only into this tip 8, and the sample is then dispensed. When finished, the tip 8 is removed from the tip of each syringe 2, a new tip 8 is attached, and the new tip 8 is used to aspirate the sample.

The attachment of this tip 8 to each syringe 2 is as follows:
The chips 8 are aligned and inserted into the respective holding holes 90 of a chip rack 9 which can be disposed below the head 3, and the head 3 is removed by lowering the head 3 or raising the chip rack 9.
This is done by pushing the tip of each syringe 2 supported by the tip into the open opening 80 at the top of each tip 8 held by the tip plug 9 and fitting each syringe 2 and each tip 8 together. .

By the way, if each tip 8 attached to the tip of each syringe 2 is not tightly and tightly fitted to the syringe 2 in this way, air leakage may occur when sampling a specimen by suction. This causes problems such as making it impossible to sample the specimen or insufficient suction volume, and causing the inconvenience that the tip 8 comes off when dispensing the specimen. This problem may be due to individual differences in the chip 8 itself, manufacturing errors in the holding holes 90 formed in the chip plate 9, or problems with the head 3.
Due to errors when assembling each syringe 2, some of the parallel syringes 2 inevitably end up with chips 8 that are incompletely fitted.

The purpose of the present invention is to reliably prevent misfitting of the tips 8 that may occur when the tip of the syringe 2 supported by the head 3 is fitted and attached to the tips 8 held in parallel on the tip rack 9. The aim is to propose new means of prevention.

Next, the means of the present invention for achieving this object will be explained in detail with reference to the drawings of the embodiments. In addition, the drawing code is
The same reference numerals are used for the same parts.

In Fig. 4, 1 is a mount to be mounted on the aircraft a, 3
A head is supported on the pedestal 1 so as to be able to rise and fall freely, and a syringe 2 is attached to the head 3 in parallel.

The syringe 2 has a cylinder 20 that has a cylinder portion 20a that fits into the piston 21, and a tip 8.
The cylinder part 20a has a front end face of a support base 30 fixed to the head 3, and a holder 33 attached to the front end face with screws 32. The upper end side is held between them, and the lower end is supported by the notch groove 34 of another support stand 30 arranged below the fixed support stand 30 and fixed to the head 3. On the other hand, the tip 20b is supported in a fixed state, but the tip 20b is placed further below the fixed support base 30 and fixed to the head 3, as shown in FIG. Holding cylinder part 36
The head 3 is held in the holding cylinder part 36 so as to be freely movable up and down within a certain range, and is biased downwardly by a spring 37 so as to be located at the lower limit position. When the chip 8 is inserted into the chip 8 by lowering or raising the chip plug 9, the chip 8 is inserted with a constant spring pressure set by the spring 37, and is also fitted into the chip 8 with a predetermined pressure. After that, spring 37
is compressed so that the inside of the holding cylinder part 36 rises toward its upper limit position. The tip 20 is supported by the head 3 in a vertically movable manner.
b and the cylinder portion 20a fixedly supported by the head 3 are connected by a flexible tube 38 as shown in FIG.

The actuating member 4 for raising and lowering the piston 21 of the syringe 2 is rotatably supported by a piece 40 fixed to the head 3 on a lifting plate 31 to which the head of each piston 21 is connected. Screw rod 41...
The lower ends of each are connected by screws, and the lifting board 31 is suspended and supported by the screw rods 41, and the rotation of the motor M supported on the sprocket 42 provided at the upper end of the screw rods 41 and the head 3 is supported. A conduction chain 44 is routed around a sprocket 43 provided on the shaft, and the motor M is rotated in forward and reverse directions to rotate the screw rods 41 in forward and reverse directions, thereby raising and lowering the elevator plate 31.

In the illustrated embodiment, S is a photo sensor for counting the number of revolutions for controlling the amount of rotation of the motor M and setting the amount of dispensing;
Reference numeral 10 denotes a chip rack station provided on the machine body a to accommodate the chip rack 9, and a collection hopper 10 provided in the machine body 1 so as to be removable and inserted into the machine body 1 to collect used chips.

Next, to explain the operation and effect, as mentioned above, the inspection dispensing device according to the present invention has the following advantages:
The cylinder portion 20a that fits into the piston 21
The cylinder part 20a is fixed and supported by the head 3, and the tip part 20b is supported on the head 3 so as to be able to move up and down within a certain range, and is moved to the lowering side. Since the cylinder portion 20a and the tip portion 20b are biased by a spring 37 and connected by a flexible tube, the head 3 may be lowered relative to the tip plate 9 (and the tip plate 9 may be raised). ) Chip 8 aligned and held in the chip plate 9
When fitting the tips 20b of the syringes 2 supported in parallel to the head 3, the tip 8 and the tips 20b of the syringes 2 fitted first press against the spring 37. By being raised, the tips 20b of the other syringes 2 will fit deeply into the open openings 80 of the tips 8, so that the tips 8 will fully fit into the tips 20b of all the syringes 2. I will continue to do so.

[Brief explanation of drawings]

Fig. 1 is a schematic plan view of the inspection dispensing device, Fig. 2 is a perspective view of the main parts of the conventional device, Fig. 3 is a side view of the chip, and Fig. 4 is a partially broken view of the main parts of the device of the present invention. FIG. 5 is a longitudinal sectional front view of the same portion. Explanation of drawing symbols, a... Airframe, 1... Frame, 1
0...Collection hopper, 2...Syringe, 20...
Cylinder, 20a... Cylinder part, 20b... Tip, 21... Piston, 3... Head, 30...
...Support stand, 31...Elevating board, 32...Screw, 33
... Holder, 34 ... Notch, 35 ... Fixed plate, 36 ... Holding tube, 37 ... Spring, 38 ...
Tube, 4... Operating member, 40... Piece, 41...
...Threaded rod, 42... Sprocket, 43... Sprocket, 44... Conduction chain, 5... Test tube rack, 50... Test tube, 6... Rail, 7... Empty test tube rack, 70... Empty test tube, U...Sample texturing station, V...Sampled rack station, W...Empty rack station, Y...Dispensed rack station, X...
...chip station, 8...chip, 8
0...Top opening, 9...Chip plug, 90
...Holding hole, M...Motor, S...Photo sensor.

Claims (1)

[Claims] 1 Each cylinder 20 of the syringe 2... provided in parallel with the head 3 has a cylinder part 20a that fits into the piston 21, and a tip part 20 that fits the tip 8.
The cylinder part 20a is fixed and supported on the head 3, and the tip part 20b is supported on the head 3 so that it can move up and down within a certain range, and is biased downward by a spring 37. A dispensing device for inspection characterized by connecting a tip portion 20a and a tip portion 20b with a flexible tube.