JPH0155015B2 - - Google Patents

Description

Detailed Description of the Invention (Field of Industrial Application) The present invention relates to an instrument for skin testing by injuring multiple points on the skin and supplying a test liquid. It relates to products used for skin tests such as functional tests or drug hypersensitivity reaction tests (hereinafter referred to as allergy).

(Prior Art) Allergy is a hypersensitive reaction caused by a certain substance acting on a living body, and can lead to diseases such as urticaria, allergic conjunctivitis, asthma, atopic dermatitis, and allergic rhinitis. In such allergy diagnosis, knowing what kind of substance the patient is allergic to and how many types there are is a medically important diagnostic tool and the first step in treatment.

Currently, the most common method is to intradermally inject the test solution into multiple points on the skin of the arm or back. If the patient exhibits symptoms such as wheals (swelling that looks like a mosquito bite), it is determined to be positive, and tests are conducted to determine if the patient is allergic to the substance. In this case, it was customary to test multiple points at once.

However, administering multiple injections not only takes time to conduct the test, but also poses a problem in that children in particular are reluctant to administer the test, and doctors must prepare hundreds of syringes in advance to accommodate the number of patients. It was hot. In addition, with intradermal injection, if the test solution accidentally enters the blood vessel, there is a risk that allergic symptoms will be induced rapidly and severely, resulting in shock symptoms.

The invention of a multi-point skin testing device disclosed in Japanese Patent Publication No. 14071/1983 is known as a solution to the above-mentioned problems caused by intradermal injection. This skin testing device consists of a handle portion in the form of an elongated flat plate, connecting members that extend from the left and right sides into a rod shape and whose distal ends are bent downward, and a handle portion that is directed downward from the distal ends of the connecting members and arranged at predetermined intervals. It is composed of press needles spaced apart from each other.

(Problems to be Solved by the Invention) According to such a device, a pressure needle must be inserted into the base block, which stores test liquids in respective recesses, as shown in Figure 5 of the same publication, and the test liquid must be applied. , there is a risk of contamination of the base block itself. In this case, as shown in FIG. 6 of the same publication, a structure may be considered in which a tube containing the test liquid is previously assembled to the pressure needle.

However, in any case, since the test liquid is predetermined, it has a fatal flaw in that it is impossible to perform tests that immediately respond to the patient's symptoms, and it has been impossible to put it into practical use.

Therefore, if it is combined with the technique for attaching and detaching the punch member and the holder shown in Japanese Patent Publications No. 49-19597, No. 51-19277, and No. 51-19719, it is predicted that the punch member can be magnetized and replaced with the connecting member. be done. However, the punch member disclosed in Japanese Patent Publication No. 49-19597 is equipped with a non-water-absorbing elastic filler and an easily penetrating body with liquid at the base of the pressing needle, whereas the punch member disclosed in Japanese Patent Publication No. 51-19277 is equipped with a non-water-absorbing elastic filler and an easily penetrating body with liquid at the tip of the pressing needle. A thermoplastic film with a wet, easy-to-penetrate mat attached is thermally bonded, and the one disclosed in Japanese Patent Publication No. 51-19719 is equipped with a locking ring on the outer diameter of the mouth rim to hold the liquid-retaining mat. . Therefore, each punch member has a complicated structure and is expensive, and a large number of these punch members must be attached and detached for each inspection, which increases the burden during inspection work.

In addition to the above, intradermal injection for allergen testing,
It is desirable to be able to adjust the amount of test liquid used depending on the thinness of the skin, the muscle condition of the region, or the patient's symptoms. For example, appropriate tests could not be obtained without procedures such as increasing the amount of test solution for patients with slow reactions or using less test solution for hypersensitive patients.

Therefore, the present invention was developed in view of the above-mentioned current situation, and an object of the present invention is to enable a multi-point allergy skin test depending on the patient's symptoms.

(Means for Solving the Problems) A multi-point skin testing device according to the present invention to achieve the above object has a plurality of punch members each having a plurality of pressure needles that injure the skin in a grippable holder body. They are spaced apart from each other, allowing multiple points of skin testing to be performed at once. Its feature is that it consists of a cartridge in which a large number of the above-mentioned punch members are integrally connected and detachably attached to the holder body at once, and the holder body supplies different test liquids to the pressing needles of each punch member. Each bottle is screwed together in a replaceable manner, and each bottle is provided with a retractable abdomen and an extraction port, and the abdomen that protrudes depending on the amount of screwing is pressed by the upper end surface of the punch member. The configuration is as follows.

(Function) By screwing the bottle onto the holder body, the test solution corresponding to the patient's symptoms is prepared. At that time, by adjusting the amount of screw engagement depending on the patient, the type of test liquid, etc., the amount of protrusion of the abdomen is determined and the amount of test liquid to be used is determined.

If the holder main body is held in this state and the pressure needle is applied to the skin of the patient to be examined, and then the holder main body is pressed, the pressure needle of the punch member will damage the skin. At the same time, the abdomen of the bottle is pressed by the upper end surface of the punch member, so that the test liquid is supplied from the extraction port to each wound site on the skin, making it possible to conduct a skin test.

After that, the cartridge to which the punch member is connected may be removed from the holder body and a new cartridge may be installed.

(Embodiment) Figures 1 to 4 show a first embodiment of the multi-point skin testing device according to the present invention, with Figure 1 being a partially cutaway perspective view of the same, and Figure 2 being a partially cutaway view. FIG. 3 is a sectional view taken along the line -- in FIG. 1 to explain the state before pressing, and FIG. 4 is a sectional view taken along the line -- in FIG. 1 to explain the pressed state.

The skin test device is composed of a holder main body 1 of a size that can be grasped, a cartridge 2 that is detachably attached to the holder main body 1 and capable of damaging multiple points on the skin, and a supply section 3 for supplying a test liquid to the cartridge 2. There is.

To be more specific, the holder main body 1 has a flat holder part 11 formed below a grip part 10 in a substantially inverted T-shape as a whole. The gripping portion 10 has a thin structure with reinforcing ribs 12 to prevent deformation when pressed.
is provided. The holder part 11 has a desired thickness, and magnetized parts 14, 14 are provided at both lengthwise ends of the lower surface 13 to which the cartridge 2 is removably magnetized.
is formed. The magnetized portion 14 is located on the lower surface 13 of the holder.
It can be constructed from a yoke and a magnet on approximately the same plane as the yoke.

Further, in the holder section 11, bottles 30 constituting a supply section 3 for multiple types of test liquids are arranged at predetermined distances from each other. The bottle 30 contains a test liquid in its hollow interior, and has a male threaded portion 31 screwed into a female threaded hole 15 of the holder portion 11 . The bottle 30 has a retractable abdomen 32 and an extraction port 3.
3 is formed, and as shown in FIG. 3, the extraction port 33 is located inside the female screw hole 15 in the screwed mounting position.

Further, the cartridge 2 has a punch member 20.
A large number of ... are placed in positions corresponding to the number of bottles,
These are integrally connected by a frame portion 21. Further, the cartridge 2 is provided with metal pieces 22, 22 at both end positions in the length direction corresponding to the magnetized portion 14. It is preferable that the metal piece 22 is on the same plane as the frame part 21 as shown in the figure, but it can be made to protrude depending on the magnetizing force.

To explain the punch member 20 in detail, it has a cylindrical shape as a whole and has a cylindrical part 23 as a supply part 3, and an upper part 23a of the punch member 20 has a supply part 24 from a bottle 30, and a communication hole 25 is formed in the upper part 23a of the punch member 20. A pressing needle 26 protrudes from the end surface 23c of the lower cylindrical portion 23b.
The test liquid can be supplied to the The upper cylindrical portion 23a protrudes beyond the upper surface of the frame portion, and its upper end surface 23d is in contact with each shoulder portion 34 of each abdomen 32 in the attached state.

According to the above configuration, when the cartridge 2 is attached to the holder main body 1, if the cartridge 2 is positioned on the lower surface of the holder 11, the magnetized portion 14 magnetizes the metal piece 22. In this case, since the contractile force of the abdomen 32 is configured to be slightly stronger than the above-mentioned magnetic absorption force, it is temporarily fixed through the gap α as shown in FIG.

In use, if you hold the grip part 10 and press the pressure needle 26... on the skin (not shown),
As shown in FIG. 4, the abdomen 32 is in a contracted state at the upper end surface 23d of the cylindrical portion, and the pressing needle 25 is in a contracted state.
may damage multiple points on the skin at the same time. At the same time, a certain amount of each test liquid is dripped from the extraction port 33 as each abdomen 32 contracts. The test liquid flows from the supply path 24 through the communication hole 25 to the pressure needle 26, so that it is supplied to the wound site.

After use, when the grip part 10 is gripped and released from the arm part, the cartridge 2 is restored as shown in FIG. 3 by the restoring force of the abdomen 32, and the supply of the test liquid is also stopped. Therefore, the cartridge 2 can be removed against the magnetizing force, and a new cartridge 2 can be reinstalled and used in the same manner as described above.

According to the above embodiment, the following effects are achieved.

Since the structure is such that the test liquid is dripped at the same time as the skin is damaged, there is no contamination of the test liquid with bacteria, and accurate tests can be performed at all times. Additionally, since the structure is such that dripping stops when pressure is released, there is no possibility of bacteria entering the inside of the bottle.

By screwing the bottle 30 together, it is possible to replace the test liquid with the type that corresponds to the patient's symptoms, and also adjust the position of the bottle shoulder 34 depending on the amount of screwing to adjust the amount of dripping. can be fine-tuned.

Since each abdomen 32 is pressed uniformly by the upper end surface 23d of each cylindrical portion of the cartridge 2, the same appropriate amount of test liquid can be supplied to each wound site at multiple points.

Figures 5 and 6 show a second embodiment of the multi-point skin testing device according to the present invention, with Figure 5 being an exploded perspective view and Figure 6 being a cross-sectional view taken along the line - - of Figure 5. . Since the same reference numerals as in the first embodiment indicate equivalent parts, repeated explanation will be omitted.

An adhesive sheet material 27 is provided on the upper surface of the cartridge 2. As the adhesive sheet 27 material, a material having elasticity is used.

In use, when the release paper 28 is peeled off and the adhesive surface 27a is adhesively attached to the holder lower surface 13, a gap α is formed depending on its thickness. Therefore, when the punch members 20 are pressed against the skin surface, the adhesive sheet 27 is contracted and the test liquid is extracted from the bottle 30 at the same time. After use, the release sheet 27 is restored and separated by the elastic force of the release sheet 27, and by pulling it from the frame 21 of the cartridge 2, it can be removed from the adhesive surface 27a and replaced.

According to this embodiment, the bottle can be manufactured without considering the contraction force of the bottle abdomen 32, and
It can be easily attached by peeling off the release paper 28.

The configurations described in the first and second embodiments may be implemented in combination with each other to the extent possible, which is also included in the embodiments of the present invention.

Further, as for the attachment/detachment structure, in addition to magnetization or adhesion, it is also possible to change the design so that the cartridge engages male and female with unevenness or the like with respect to the lower surface of the holder.

(Effects of the Invention) As explained above, the multi-point skin testing device according to the present invention provides the following effects.

When performing skin tests on multiple points at once, you can easily select the test liquid according to the patient's symptoms by changing the bottle, as with conventional injections, and adjust the amount of liquid to the patient by adjusting the amount of screwing. This can contribute to the optimization of allergen testing.

Since the bottle can be replaced by screwing the bottle onto the holder body, it is possible to easily select the test liquid and prevent contamination with bacteria during replacement.

The test liquid is supplied externally from the extraction port only once when the abdomen is pressed at the same time as the skin is injured, so even if it is used on many patients, there is no possibility that the test liquid or the inside of the bottle will be contaminated with bacteria. There is no fear of contamination, each used punch member can be replaced at the same time using a cartridge, and accurate inspection can be performed continuously.

[Brief explanation of drawings]

Figures 1 to 4 show a first embodiment of the multi-point skin testing device according to the present invention, with Figure 1 being a partially cutaway perspective view of the same, and Figure 2 being a partially cutaway exploded view of the same. A perspective view, FIG. 3 is a sectional view taken along the - line in FIG. 1 to explain the state before pressing, FIG. 4 is a sectional view taken along the - line in FIG. A second embodiment of the multi-point skin testing device according to the invention is shown, and FIG. 5 is an exploded perspective view of the same;
FIG. 6 is a sectional view taken along the line -- in FIG. 5. 1...Holder body, 2...Cartridge, 3...
... Supply section, 10 ... Grip section, 11 ... Holder, 1
4... Magnetized part, 20... Punch member, 22... Metal piece, 27... Adhesive sheet material, 30... Bottle.

Claims (1)

[Scope of Claims] 1. An instrument in which a large number of punch members each having a plurality of pressure needles that injure the skin are arranged in a grippable holder body and are arranged at a distance from each other so that a skin test can be performed at multiple points at once, It consists of a cartridge in which a large number of the above-mentioned punch members are integrally connected and are detachably attached to the holder body at once, and each bottle that supplies a different test liquid to the pressing needle of each punch member can be replaced in the holder body. The bottle is provided with a retractable abdomen and an extraction port, and the abdomen that protrudes depending on the amount of screwing is pressed by the upper end surface of the punch member. Multi-point skin testing device.