JPH0232242B2 - FURANBYOBOJOZAI - Google Patents
FURANBYOBOJOZAIInfo
- Publication number
- JPH0232242B2 JPH0232242B2 JP24492087A JP24492087A JPH0232242B2 JP H0232242 B2 JPH0232242 B2 JP H0232242B2 JP 24492087 A JP24492087 A JP 24492087A JP 24492087 A JP24492087 A JP 24492087A JP H0232242 B2 JPH0232242 B2 JP H0232242B2
- Authority
- JP
- Japan
- Prior art keywords
- hinokitiol
- rot
- causing
- area
- furanbyobojozai
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 claims description 22
- 229930007845 β-thujaplicin Natural products 0.000 claims description 11
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 claims description 10
- 201000010099 disease Diseases 0.000 claims description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims 1
- 229940090972 beta-thujaplicin Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 241000233866 Fungi Species 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 230000003902 lesion Effects 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000011550 stock solution Substances 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 238000003912 environmental pollution Methods 0.000 description 2
- 230000000887 hydrating effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 241001512566 Valsa mali Species 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- RIOXQFHNBCKOKP-UHFFFAOYSA-N benomyl Chemical compound C1=CC=C2N(C(=O)NCCCC)C(NC(=O)OC)=NC2=C1 RIOXQFHNBCKOKP-UHFFFAOYSA-N 0.000 description 1
- 229910052906 cristobalite Inorganic materials 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- 239000003673 groundwater Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000010721 machine oil Substances 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
イ 発明の目的
[産業上の利用分野]
本発明は、ヒノキチオールを用いた植物の腐乱
病原因真菌(VaIsa mali)防除剤に関するもの
である。下記にヒノキチオールの化学構造式を示
す。
[従来の技術]
従来は、トツプジン水和剤、ベンレート水和剤
及びベフラン液剤などの薬剤を用いているが、単
に消毒するだけで腐乱病原因真菌に直接作用する
適当な薬剤はない欠点があつた。また、病変部は
削り取るか、被害が多大な場合には伐採処理を行
つた後焼却しなければならないという欠点があつ
た。加えて、発芽時期の薬剤処理は薬害を生じる
欠点があつた。更に上記薬剤は天然に存在しない
合成化学薬品であり、毒物・劇物に指定されてい
ることから土壌及び地下水等の環境汚染が生じる
欠点があつた。
ロ 発明の構成
[問題点を解決するための手段]
そこで本発明はこれらの欠点を考慮し、ヒノキ
チオールの高い抗菌作用を用いて、安価で簡易
に、しかも環境汚染を伴わずに植物の腐乱病防除
剤の提供を図るものである。
[作用]
天然及び合成ヒノキチオールを用いて腐乱病の
病原真菌(Valsa mali)に対する抗菌性試験を
最少発育阻止濃度法(MIC法)によつて行つた
ところ、表1の通り25.0μg/mlの濃度で発育を
完全に阻止することが明らかとなつた。
[実施例]
以下、発明の実施例を示す。
実施例 (1)
ヒノキチオール1部を30%エタノール水溶液99
部に溶解し、これを原液とする。使用に際して
は、この原液を400倍に水で希釈し、病変部及び
その周辺を切除した部位に塗布又は噴霧する。
実施例 (2)
エタノール100mlにヒノキチオール1gを溶解
し、これをゼオライト、活性炭又はクリストバラ
イトの粉末1000cm3に吸着させる。使用時には、薬
剤1部に対しパラフイン24%製剤150部を混和す
る。
実施例 (3)
青森ヒバおがくず(ヒノキチオール0.02%含
有)1Kgに、実施例(1)の原液と酢酸ビニルエマル
ジヨンを重量比1:10の割合で混合したもの
100g混和し、病変部及びその周辺切除した部位
に塗布する。
実施例 (4)
エタノール5mlに0.05gのヒノキチオールを溶
解した後、マシン油乳剤1000mlに混和する。こ
れを病変部及びその周辺を切除した部位に塗布す
る。
ハ 発明の効果
以上のごとく、実施例にしたがつて実験を行つ
た結果、表2のとおり顕著な効果が認められた。
本薬剤の主成分であるヒノキチオールは、天然
系物質であり、生物に対する毒性は極めて弱く、
しかも、手軽に使用できる特徴がある。又、腐乱
病真菌に対するMIC値が特に低いので微量で多
大な効果がある。さらにまた、これまで腐乱病に
効果のある薬剤がないため主として毒
B. Object of the Invention [Field of Industrial Application] The present invention relates to a control agent for a plant rot-causing fungus (VaIsa mali) using hinokitiol. The chemical structural formula of hinokitiol is shown below. [Prior art] Conventionally, drugs such as Topudin hydrating powder, Benlate hydrating powder, and Befuran solution have been used, but there is a drawback that there is no suitable drug that directly acts on the fungus that causes rot disease by simply disinfecting. Ta. Another disadvantage is that the affected area must be scraped off, or if the damage is extensive, it must be cut down and then incinerated. In addition, chemical treatment during the germination period has the disadvantage of causing chemical damage. Furthermore, since the above-mentioned drugs are synthetic chemicals that do not exist in nature and are designated as poisonous or deleterious substances, they have the disadvantage of causing environmental pollution such as soil and groundwater. B. Structure of the Invention [Means for Solving the Problems] Therefore, the present invention takes these drawbacks into consideration and uses the high antibacterial activity of hinokitiol to treat plant rot diseases inexpensively and easily, and without causing environmental pollution. The aim is to provide a pest control agent. [Effect] When natural and synthetic hinokitiol were used to conduct an antibacterial test against a rot-causing fungus (Valsa mali) using the minimum inhibitory concentration method (MIC method), the concentration was 25.0 μg/ml as shown in Table 1. It has become clear that the growth can be completely inhibited. [Examples] Examples of the invention will be shown below. Example (1) 1 part hinokitiol in 30% ethanol aqueous solution99
This is used as a stock solution. To use, dilute this stock solution 400 times with water and apply or spray it on the lesion and the area around it that has been excised. Example (2) Dissolve 1 g of hinokitiol in 100 ml of ethanol and adsorb it onto 1000 cm 3 of zeolite, activated carbon or cristobalite powder. When used, 150 parts of a 24% paraffin preparation is mixed with 1 part of the drug. Example (3) 1 kg of Aomori Hiba sawdust (containing 0.02% hinokitiol) was mixed with the stock solution of Example (1) and vinyl acetate emulsion at a weight ratio of 1:10.
Mix 100g and apply to the affected area and surrounding area that has been excised. Example (4) Dissolve 0.05 g of hinokitiol in 5 ml of ethanol and then mix with 1000 ml of machine oil emulsion. Apply this to the area where the lesion and surrounding areas have been excised. C. Effects of the invention As described above, as a result of conducting experiments according to the examples, remarkable effects were observed as shown in Table 2. Hinokitiol, the main component of this drug, is a natural substance and has extremely low toxicity to living organisms.
Moreover, it has the feature of being easy to use. In addition, since the MIC value against rot fungi is particularly low, a small amount can have a great effect. Furthermore, since there are currently no effective drugs against rot diseases, they are mainly poisonous.
【表】
−:発育なし +:発育あり
[Table] -: No growth +: Growth
【表】
腐乱病原因真菌 効果 効果 効果 効果
による病変部 あり あり あり あり
[Table] Rot-causing fungi Effect Effect Effect Effect Lesion area Yes Yes Yes Yes
Claims (1)
成分として含有することを特徴とする腐乱病防除
剤。1. A rot disease control agent characterized by containing hinokitiol (β-thujaplicin) as an active ingredient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24492087A JPH0232242B2 (en) | 1987-09-30 | 1987-09-30 | FURANBYOBOJOZAI |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24492087A JPH0232242B2 (en) | 1987-09-30 | 1987-09-30 | FURANBYOBOJOZAI |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6490102A JPS6490102A (en) | 1989-04-06 |
| JPH0232242B2 true JPH0232242B2 (en) | 1990-07-19 |
Family
ID=17125940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP24492087A Expired - Lifetime JPH0232242B2 (en) | 1987-09-30 | 1987-09-30 | FURANBYOBOJOZAI |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0232242B2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2184998A2 (en) * | 2007-07-24 | 2010-05-19 | Marrone Bio Innovations, Inc. | Hinokitiol as a plant pesticide |
| DE102009032895B4 (en) | 2009-07-10 | 2016-06-23 | Chevita Tierarzneimittel-Gesellschaft M.B.H. | Composition and method for the prevention and treatment of fire blight |
-
1987
- 1987-09-30 JP JP24492087A patent/JPH0232242B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6490102A (en) | 1989-04-06 |
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